US20090240265A1 - Eversion apparatus and methods - Google Patents
Eversion apparatus and methods Download PDFInfo
- Publication number
- US20090240265A1 US20090240265A1 US12/235,445 US23544508A US2009240265A1 US 20090240265 A1 US20090240265 A1 US 20090240265A1 US 23544508 A US23544508 A US 23544508A US 2009240265 A1 US2009240265 A1 US 2009240265A1
- Authority
- US
- United States
- Prior art keywords
- vessel
- eversion
- handle
- graft
- everting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
Definitions
- This invention relates to apparatus and methods for preparing a tubular graft for an anastomosis procedure. More particularly, the invention involves apparatus and methods for everting a graft prior to anastomosing the graft to another tubular structure such as an aorta.
- occlusion of the arteries can lead to insufficient blood flow resulting in discomfort and risks of angina and ischemia.
- Significant blockage of blood flow in the coronary artery can result in damage to the myocardial tissue or death of the patient.
- occlusion of the artery results from progressive long term deposits of plaque along the artery wall. While such deposits may be concentrated and occlude the artery at a particular site, the deposits are most certainly present throughout the arteries and the vascular system.
- Coronary artery bypass graft (CABG) surgery is a surgical procedure performed in severe cases of coronary blockages.
- CABG procedures involve anastomosing an artery to a graft, such as a vascular graft, which restores the flow of blood by establishing another pathway around the occluded vasculature.
- a vein or other conduit can be attached proximally to the patient's aorta. The other end is attached to the blocked artery, downstream from the obstruction, thus bypassing the coronary occlusion.
- CABG procedures can be done by placing the patient on a heart-lung machine and stopping the heart from beating or they can be done on a beating heart without a heart lung machine.
- Vessel eversion apparatus have been disclosed to prepare vascular grafts for anastomosis.
- vessel everting apparatus is described in U.S. Pat. No. 5,076,161 to Kirsch, et al. and U.S. Pat. No. 6,176,413 to Heck, et al.
- the present invention involves improvements in anastomosis apparatus and methods for anastomosing a first tubular structure to a second tubular structure.
- eversion apparatus for preparing a conduit, such as a vessel, for anastomosis in a human patient comprises an everting member having a loop shaped portion adapted to be inserted into an end portion of a conduit from a human patient and configured to fold a portion of the conduit end portion over itself when it is moved away from the conduit end and along the conduit while a portion of the conduit is held fixed relative thereto.
- the eversion apparatus facilitates eversion of a vascular or nonvascular graft, for example, so that the intimal surface of the graft and the intimal surface of the target conduit, such as a vessel, can be placed in contact with one another for the anastomosis.
- the eversion apparatus also facilitates rapid graft eversion which can expedite the anastomosis procedure. In cases where the surgeon must complete the graft in as little time as possible due to the absence of blood flowing through a vessel such as the aorta in a CABG procedure, this can be especially advantageous. If blood flow is not promptly restored, sometimes in as little as 30 minutes, the tissues the artery supplies may experience significant damage or necrosis.
- a conduit or vessel eversion system for preparing a conduit or vessel for anastomosis in a human patient comprises a conduit or vessel support device having a proximal end and a distal end; and everting apparatus comprising an everting member, the everting member having a loop shaped portion adapted to be inserted into a portion of a conduit or vessel to be prepared for an anastomosis in a human patient and evert the portion of the conduit or vessel over the conduit or vessel support device when the conduit or vessel is coupled to the support device with an end portion thereof extending from the distal end of the support device.
- a method of everting a graft comprises positioning a graft in a support device such that an end portion of the graft extends therefrom; introducing a generally looped shaped member into the end portion of the graft extending from said support device; and moving the looped shaped member over the support device to fold at least a portion of the end portion of the graft over the support device.
- FIG. 1 is a perspective view of an eversion tool constructed according to the principles of the present invention
- FIG. 2 is a side elevational view of the eversion tool of FIG. 1 ;
- FIGS. 3A and 3B are top plan views of the eversion tool of FIG. 1 where FIG. 3A shows the everting member or loop adjusted to a first diameter and FIG. 3B shows the everting member or loop adjusted to a second larger diameter;
- FIGS. 4A and 4B illustrate another embodiment of the eversion tool where FIG. 4A shows the everting member or loop adjusted to a first diameter and FIG. 4B shows the everting member or loop adjusted to a second larger diameter;
- FIG. 5 illustrates another embodiment of the eversion tool
- FIGS. 6A-6D schematically illustrate everting a graft vessel using the eversion tool of any one of FIGS. 1-5 , where FIG. 6A illustrates presenting the distal end portion of the graft vessel in a graft support device, FIG. 6B illustrates insertion of the eversion tool in the distal end portion of the graft vessel, FIG. 6C illustrates everting the distal end portion of the graft vessel, and FIG. 6D illustrates removing the eversion tool from the everted graft and graft support device;
- FIGS. 7A-7D depicts another support or anastomosis device apparatus with which the eversion tool can be used, where FIG. 7A is a partial sectional view of the support device, FIG. 7B is an enlarged partial sectional view of the apparatus of FIG. 7A taken generally along line 7 B- 7 B;
- FIG. 7C shows the apparatus of FIG. 7A in a radially collapsed state with the mandrel or slide retracted allowing the arms to progressively move radially inward along the distal portion thereof
- FIG. 7D shows the apparatus of FIG. 7A in a radially expanded state with the mandrel longitudinally extended toward the distal end of the apparatus urging the arms radially outward;
- FIGS. 7E-7H illustrate everting a graft vessel using the eversion tool of any one of FIGS. 1-5 , where FIG. 7E illustrates presenting the distal end portion of the graft vessel in the graft support device of FIG. 7A , FIG. 7F illustrates insertion of the eversion tool in the distal end portion of the graft vessel, FIG. 7C illustrates everting the distal end portion of the graft vessel with the eversion tool, and FIG. 7D illustrates extending piercing member through the distal end portion of the graft vessel after the eversion tool has been removed.
- the apparatus, systems, and methods described herein can be used to connect or anastomose tubular structures or conduits together.
- the tubular structures can be vascular or nonvascular structures.
- the apparatus, systems, and methods described herein can be used in connection with coronary artery bypass grafting procedures during which a vascular conduit or graft structure, such as a vein (e.g., a saphenous vein), artery (e.g., an internal mammary artery), or an artificial conduit or graft structure, is anastomosed to an aorta, the example target structure.
- a vascular conduit or graft structure such as a vein (e.g., a saphenous vein), artery (e.g., an internal mammary artery), or an artificial conduit or graft structure, is anastomosed to an aorta, the example target structure.
- nonvascular lumens can include, but are not intended to be limited to, the bile duct, the urethra, the urinary bladder, intestines, esophagus, stomach, and bowel.
- the ideal anastomotic connection can be created when the component vessels are arranged in a situation that provides intima-to-intima contact.
- Standard suturing techniques provide some degree of this attribute, but there are inconsistencies owing to, for example, variation in operator technique and vessel preparation.
- the vessel can be everted (or cuffed). This involves manipulation of the vessel to turn a defined section inside-out to expose the internal lumen and intimal surface.
- This everted section can also be utilized to create a seal (or gasket) between the graft and the native vessel.
- the everted section can be used to form the interface at the anastomotic site that also provides a medium for desired tissue healing.
- One difficulty of vessel eversion arises when attempting to manually manipulate the tissue to create the everted section or cuff. As the tissue is semi-elastic, it has a tendency to resist manual eversion.
- the invention involves graft or vessel everting apparatus, systems and methods to prepare grafts and vessels for anastomosis and assist with the anastomosis.
- the eversion tool or apparatus of the present invention generally comprises an everting member, which comprises a flexible or pliable member or portion.
- the flexible or pliable member or portion can be semi-rigid and can be generally oval or circular with a closed or nearly closed turn. In other words, the flexible or pliable member or portion can be in the form of a loop.
- the everting member loop is inserted into one end of a graft or vessel and then manipulated to expand the graft or vessel radially outward so that the graft or vessel can be everted or draped over a vessel holder or support device, which will be described in more detail below.
- the everting member loop can have variable shapes and/or diameters to accommodate variously sized vessel support devices and to facilitate ease of its removal therefrom.
- the eversion tool also can include a handle to support the everting member.
- Eversion tool 100 generally comprises an everting member 104 , which comprises a flexible or pliable member having a portion that is in the form of a circular loop.
- the generally circular loop can be nearly closed or closed. It should be understood, however, the flexible and/or pliable characteristics allow the loop to be readily reshaped.
- One suitable material for flexible or pliable member 104 can be stainless steel wire, such as 304 series stainless steel wire, or nitinol wire. The wire typically will have a diameter ranging from about 0.002 to 0.015 inch.
- eversion tool 100 includes handle 102 for supporting everting member 104 .
- handle 102 can be tubular. It also can have a collar at its distal end as shown in FIGS. 7E-G .
- the handle can be made from any suitable material such as a machined metal (e.g., stainless steel) or injection molded plastic.
- everting member 104 is slidably mounted in handle 102 . More specifically, the ends of a straight wire (e.g., a nitinol wire) can be brought together and inserted into the handle without platically deforming the wire. This facilitates adjustment of the size of the everting member loop extending from handle 102 by moving the ends of the wire. One can move proximally located everting member ends 104 a and 104 b relative to handle 102 to adjust the length of the elongated everting member portion extending from the distal end of handle 102 to adjust the loop size. In FIG. 3A , the distal ends 104 a and 104 b are in first position and in FIG.
- a straight wire e.g., a nitinol wire
- Eversion tool 100 ′ is the same as eversion tool 100 with the exception that one portion of everting member 104 is fixedly secured to handle 102 .
- everting member 104 b is fixedly secured to handle 102 .
- the loop can be preformed with other shapes such as oblong, oval or teardrop shapes.
- Eversion tool 100 ′′ is the same as eversion tool 100 with the exception that two portions of everting member 104 are fixedly secured to handle 102 so that the length of the loop extending from the distal end of the handle is fixed.
- everting member ends 104 a and 104 b can be fixedly secured to handle 102 .
- graft support device 200 In order to assist in the understanding of the operation of the eversion tool, graft support device 200 will first be described.
- Anastomosis or support device 200 is used to hold the everted graft tubular structure (e.g., graft vessel) adjacent to or in an opening formed in a target tubular structure (e.g., target vessel) to which the graft tubular structure is to be anastomosed. More specifically, the support device supports or holds the graft tubular structure in a position relative to the target tubular structure so that the graft and target tubular structure can be secured to one another with known fasteners such as sutures or surgical clips.
- graft tubular structure e.g., graft vessel
- target tubular structure e.g., target vessel
- Anastomosis or support device 200 comprises a proximal portion and a distal portion.
- the distal portion has a plurality of arms (or fingers) 206 that are configured to hold the everted portion or flap “E” of a tubular graft structure “G” as shown in FIGS. 6C and 6D .
- Adjacent arms are configured and arranged to form spaces, such as spaces 208 , suitable for receiving surgical fasteners therethrough.
- Support device 200 can be described as a slotted tubular member, each slot having an open distal end and a closed end. After the support device has been positioned in the desired position and fasteners passed through a desired number of the slots through graft tubular structure and the target tubular structure, the open ends allow removal of the anastomosis or support device without disrupting the fasteners.
- Anastomosis device or support 200 can be made from any suitable plastic or metal.
- the device can be made from ABS plastic material or stainless steel tubing such as 304 stainless steel tubing.
- the length of the device typically ranges from about 25 mm to about 125 mm depending on the application. In aortic applications, it typically ranges from about 25 mm to about 70 mm.
- the inner diameter of the tube typically ranges from about 1 mm to about 25 mm also depending on the application. For example, the inner diameter typically can vary from about 3 mm to about 6 mm when sized for an aortic anastomosis where the tube thickness can range from 0.1 mm to 2 mm.
- the tube inner diameter can be up to about 25 mm when sized for applications concerning the bowel.
- the tube can have any number of slots or openings, but typically will have 4 to 12 slots cut into its side or the number of arms selected and arranged to form 4 to 12 openings.
- the slots or openings typically extend a length of about 2 mm to about 25 mm and have a width of about 0.2 mm to about 5 mm. In aortic applications, the slot length typically can range from about 5 mm to about 25 mm and the slot width typically can range from about 0.2 mm to 2.5 mm.
- the desired number of sutures or clips to be used for a particular anastomosis can determine the number of spaces or slots that the anastomosis device should have. That is the number of openings can match the number desired fasteners. However, it should be understood that the number of openings need not necessarily match the number of fasteners.
- the tube can be split down the side to facilitate its placement in and removal from the tubular graft structure.
- the split allows the tube to be compressed and deformed to fit into small openings in the target vessel.
- the split can be expanded to assist in removing the graft from the device.
- the tube can comprise or be made of shape memory material or alloy so that the compressed split tube returns to a shape memory tubular shape that is approximately equal to or slightly larger the opening into which it is inserted.
- the tube construction can provide for some elastic deformation in the radial direction if radially compressed so that its annular dimension can be decreased to some degree, which can be desirable when introducing the device into an opening formed in a vessel where the opening is slightly smaller in diameter than the diameter of device 200 in the uncompressed state.
- the wall thickness can be selected (e.g., reduced) to provide such elastic deformation.
- Other factors that can be used to achieve this effect include, but are not limited to a slot number, slit width, and material selection as would be apparent to one of skill in the art.
- the tubular member can comprise or be made of nitinol.
- Support device 200 can be cylindrical as shown in the drawings or it can have other shapes suitable for the intended purpose. For example, it can have a rectangular or oval configuration. Other construction examples include, but are not limited to, mesh tubes, wire framed constructions, or other nonsolid wall constructions.
- tubular graft structure (e.g., graft vessel) “G” is passed between adjacent fingers 206 of support device 200 and the distal end thereof positioned to extend distally from the support device lumen.
- the tubular graft structure can be presented through the proximal end of support device 200 so that it passes along the length of the support device and extends from both the distal and proximal ends thereof.
- Eversion tool 100 or 100 ′ is prepared for insertion into the distal end of the tubular graft structure. This can include bending the everting member portion that extends from handle 102 so that the plane in which the everting member loop lies forms an angle of about 90 degrees with the longitudinal axis of the handle as shown in FIG. 6A .
- the everting member loop is adjusted to have a diameter that allows it to be readily inserted into the end of graft G.
- the loop diameter can be selected to be less than the inner diameter of the end of graft G as shown in FIG. 6A .
- the everting member loop diameter is then enlarged to mechanically expand graft G, which in this example is semi-elastic, and increase the diameter of the graft as shown in FIG. 6B .
- the eversion tool is then moved so that the everting member passes over the distal end of the support device, thereby mechanically draping the expanded end of the graft over the support device distal end as shown in FIG. 6C .
- the eversion tool can be retracted as shown in FIG. 6D .
- eversion tool 100 ′ When eversion tool 100 ′ is used with a fixed loop length, one typically does not bend the everting member to form an angle with handle 102 . In this case, the loop is inserted into the graft and pulled over the graft support device as shown in FIGS. 7E-G , which will be described in detail below.
- FIGS. 7A-D illustrate a support device 700 that also can be used in conjunction with eversion tool or apparatus 100 , 100 ′, or 100 ′′′ in accordance with the principles of the present invention.
- Support device 700 is described in co-pending U.S. patent application Ser. Nos. 10/340,161 and 10/340,164, both of which were filed on Jan. 10, 2003 and entitled Anastomosis Apparatus and Methods.
- Anastomosis or graft support device 700 generally includes a proximal portion and a distal portion, which includes a plurality of arms 706 in which piercing members 710 can be slidably mounted. More specifically, each arm forms a pathway in which a piercing member 710 is slidably mounted. Arms 706 can be tubular members (e.g., hypotubes) each having a lumen through which a piercing member 706 can slide.
- tubular members e.g., hypotubes
- Arms 706 are biased radially inward and have outer diameters that can range from 0.5 mm to 2 mm, for example, in aortic applications.
- anastomosis apparatus 700 includes a mandrel or slide 722 for radially expanding the piercing member carrying or support arms 706 .
- Each arm 706 has a proximal end secured to tubular member or arm support 720 which tapers so that the annular dimension of the arms, taken collectively, progressively decreases in the distal direction when the slide 722 is in a retracted position adjacent to arm support 720 as shown in FIG. 7A .
- the arms can be secured in circumferentially spaced longitudinal grooves formed in arm support 720 by gluing or other suitable means.
- the arms also extend along longitudinal grooves formed in mandrel or slide 722 .
- Actuator or plunger 718 extends through the device with its end secured to mandrel or slide 722 so that when the pusher is moved forwardly, it pushes the mandrel or slide 722 distally and radially expands the arms.
- a graft is everted over the distal ends of the arms as will be described below, it can be desirable to radially expand the arms when graft holder or support 700 is positioned in an opening in a target tubular structure (e.g., target vessel) to which the tubular graft structure (e.g., graft vessel) is to be anatomosed.
- a target tubular structure e.g., target vessel
- the tubular graft structure e.g., graft vessel
- the radial expansion of the arms can enhance or form a seal between the graft and the target tubular structure (e.g., an aorta).
- apparatus or device 700 further includes piercing members 710 , which are slidably mounted in arms 706 .
- Piercing members 710 have proximal portions 710 a and distal portions 710 b.
- Piercing members 710 extend from arms 706 proximally toward cylindrical piercing member support 721 where proximal portions 710 a are secured in grooves formed in cylindrical piercing member support 721 .
- Support 721 is slidably mounted on actuator or pusher 718 and secured to cylindrical knob or finger grip 714 by fastener or screw 716 ( FIG. 7B ). When knob 714 is pushed forwardly in a distal direction, the piercing members are extended as shown in FIGS.
- Housing or tubular body 712 can have a longitudinal slot 717 through which screw 716 can slide so that knob 714 can move independently from housing 712 .
- the radius of curvature of the memory shaped distal portions 710 b of the piercing members can vary. For example, a larger radius of curvature may be desired if the user wants to insert part of the device into the opening in the target structure or vessel to which the graft is to be anastomosed. On the other hand, a smaller radius of curvature may be desired if the user wants to tack the device down around the opening in the target structure or vessel, thereby seating the device on the outer wall and covering the opening with the graft.
- Distal portions 710 b have the desired memory shape to pierce the graft and vessel to which the graft is to be anastomosed when the piercing members are advanced.
- the piercing members comprise shape memory material so that the distal portions 710 b can be provided with a hook configured memory shape, which is one suitable shape for holding the graft and vessel together during the anastomosis.
- the piercing members can be made of nitinol wire and the distal portions provided with the desired memory shape as is known in the art so that they return to their memory shape when in an unbiased state (e.g., extended from arms 706 ).
- the shape memory alloy distal portions exhibit pseudoelastic (superelastic) behavior.
- Graft structure e.g., graft vessel
- the everting member loop of eversion tool 100 is introduced through the distal end of the graft structure and inserted into the graft lumen shown in FIG. 7F .
- the diameter of the everting member or loop can be increased as described above in connection with embodiments 100 and 100 ′ to expand or increase the diameter of the graft vessel to make it easier to evert the distal end portion of the graft structure over the distal end of the graft holding device.
- the everting member loop is then turned or oriented so that it can pass over the distal end portion of the support member and moved to pass over the support member distal end portion or arms 706 , thereby everting graft structure G over the support member distal end portion and forming everted portion E with the intimal surface of the graft lumen exposed and facing radially outward.
- the support device can be positioned in an opening formed in the target tubular structure and the piercing members extended as shown in FIG. 7H to hold the graft and target tubular structures together, while fasteners are used to secure the graft and target structures together.
- the surgeon cuts a hole or opening in the target tubular structure or vessel (e.g., the aorta) using a scalpel and an aorta cutting device or punch
- the surgeon covers the hole with either a finger or other suitable tool.
- the distal portion of the support device and the portion of the graft everted thereover are positioned in the vessel opening.
- the distal portions of the piercing members are extended and the mandrel is moved distally to expand the arms and everted graft against the tissue surrounding the opening so as to form a seal therewith.
- the arms can be expanded to urge the everted graft against the tissue surrounding the target vessel opening to seal the connection between the graft and target vessel.
- the piercing members are retracted and anastomosis device 700 pulled off of the graft and target structures. Additional fasteners or clips can be placed at the connection, if any blood appears to be seeping out from the graft and target vessel.
- any fastener can be used to secure the tubular graft and target structures together.
- suitable fasteners include conventional sutures and surgical clips such as the surgical clips disclosed in U.S. Pat. Nos. 5,972,024 to Northrup, et al., 6,607,541 to Gardiner, et al., 6,514,265 to Ho, et al., U.S. Patent Publication No. 2002-0010490 of U.S. patent application Ser. No. 09/260,623 filed Mar. 1, 1999 and entitled Tissue Connector Methods and Apparatus and U.S. patent application Ser. No. 09/090,305 filed Jun. 3, 1998 and entitled Tissue Connector Apparatus and Methods.
Abstract
Surgical eversion apparatus for preparing a conduit for anastomosis in a human patient comprises an everting member having a loop shaped portion adapted to be inserted into an end portion of a conduit harvested from a human patient and configured to fold a portion of the conduit end portion over itself when moved proximally away from the end of the conduit and along the conduit while a portion of the conduit is held fixed relative thereto. A method of everting a graft comprises positioning a graft in a support device such that an end portion of the graft extends therefrom; introducing a generally looped shaped member into the end portion of the graft extending from said support device; and moving the looped shaped member over the support device to fold at least a portion of the end portion of the graft over the support device.
Description
- This application is a continuation of U.S. Ser. No. 10/646,254, filed Aug. 22, 2003, entitled “Eversion Apparatus and Methods”, and bearing Attorney Docket No. P0022020.00; and the entire teachings of which are incorporated herein by reference.
- This invention relates to apparatus and methods for preparing a tubular graft for an anastomosis procedure. More particularly, the invention involves apparatus and methods for everting a graft prior to anastomosing the graft to another tubular structure such as an aorta.
- The occlusion of the arteries can lead to insufficient blood flow resulting in discomfort and risks of angina and ischemia. Significant blockage of blood flow in the coronary artery can result in damage to the myocardial tissue or death of the patient. In most cases, occlusion of the artery results from progressive long term deposits of plaque along the artery wall. While such deposits may be concentrated and occlude the artery at a particular site, the deposits are most certainly present throughout the arteries and the vascular system.
- Coronary artery bypass graft (CABG) surgery is a surgical procedure performed in severe cases of coronary blockages. CABG procedures involve anastomosing an artery to a graft, such as a vascular graft, which restores the flow of blood by establishing another pathway around the occluded vasculature. During coronary artery bypass graft surgery, a vein or other conduit can be attached proximally to the patient's aorta. The other end is attached to the blocked artery, downstream from the obstruction, thus bypassing the coronary occlusion. CABG procedures can be done by placing the patient on a heart-lung machine and stopping the heart from beating or they can be done on a beating heart without a heart lung machine.
- Vessel eversion apparatus have been disclosed to prepare vascular grafts for anastomosis. For example, vessel everting apparatus is described in U.S. Pat. No. 5,076,161 to Kirsch, et al. and U.S. Pat. No. 6,176,413 to Heck, et al. However, there remains a need to provide improved everting apparatus and methods.
- The present invention involves improvements in anastomosis apparatus and methods for anastomosing a first tubular structure to a second tubular structure.
- According to one embodiment of the invention, eversion apparatus for preparing a conduit, such as a vessel, for anastomosis in a human patient comprises an everting member having a loop shaped portion adapted to be inserted into an end portion of a conduit from a human patient and configured to fold a portion of the conduit end portion over itself when it is moved away from the conduit end and along the conduit while a portion of the conduit is held fixed relative thereto.
- The eversion apparatus facilitates eversion of a vascular or nonvascular graft, for example, so that the intimal surface of the graft and the intimal surface of the target conduit, such as a vessel, can be placed in contact with one another for the anastomosis. The eversion apparatus also facilitates rapid graft eversion which can expedite the anastomosis procedure. In cases where the surgeon must complete the graft in as little time as possible due to the absence of blood flowing through a vessel such as the aorta in a CABG procedure, this can be especially advantageous. If blood flow is not promptly restored, sometimes in as little as 30 minutes, the tissues the artery supplies may experience significant damage or necrosis.
- According to another embodiment of the invention, a conduit or vessel eversion system for preparing a conduit or vessel for anastomosis in a human patient comprises a conduit or vessel support device having a proximal end and a distal end; and everting apparatus comprising an everting member, the everting member having a loop shaped portion adapted to be inserted into a portion of a conduit or vessel to be prepared for an anastomosis in a human patient and evert the portion of the conduit or vessel over the conduit or vessel support device when the conduit or vessel is coupled to the support device with an end portion thereof extending from the distal end of the support device.
- According to another embodiment of the invention, a method of everting a graft comprises positioning a graft in a support device such that an end portion of the graft extends therefrom; introducing a generally looped shaped member into the end portion of the graft extending from said support device; and moving the looped shaped member over the support device to fold at least a portion of the end portion of the graft over the support device.
- The above is a brief description of some deficiencies in the prior art and advantages of the present invention. Other features, advantages, and embodiments of the invention will be apparent to those skilled in the art from the following description, accompanying drawings, wherein, for purposes of illustration only, specific forms of the invention are set forth in detail.
-
FIG. 1 is a perspective view of an eversion tool constructed according to the principles of the present invention; -
FIG. 2 is a side elevational view of the eversion tool ofFIG. 1 ; -
FIGS. 3A and 3B are top plan views of the eversion tool ofFIG. 1 whereFIG. 3A shows the everting member or loop adjusted to a first diameter andFIG. 3B shows the everting member or loop adjusted to a second larger diameter; -
FIGS. 4A and 4B illustrate another embodiment of the eversion tool whereFIG. 4A shows the everting member or loop adjusted to a first diameter andFIG. 4B shows the everting member or loop adjusted to a second larger diameter; -
FIG. 5 illustrates another embodiment of the eversion tool; -
FIGS. 6A-6D schematically illustrate everting a graft vessel using the eversion tool of any one ofFIGS. 1-5 , whereFIG. 6A illustrates presenting the distal end portion of the graft vessel in a graft support device,FIG. 6B illustrates insertion of the eversion tool in the distal end portion of the graft vessel,FIG. 6C illustrates everting the distal end portion of the graft vessel, andFIG. 6D illustrates removing the eversion tool from the everted graft and graft support device; -
FIGS. 7A-7D depicts another support or anastomosis device apparatus with which the eversion tool can be used, whereFIG. 7A is a partial sectional view of the support device,FIG. 7B is an enlarged partial sectional view of the apparatus ofFIG. 7A taken generally alongline 7B-7B; -
FIG. 7C shows the apparatus ofFIG. 7A in a radially collapsed state with the mandrel or slide retracted allowing the arms to progressively move radially inward along the distal portion thereof, andFIG. 7D shows the apparatus ofFIG. 7A in a radially expanded state with the mandrel longitudinally extended toward the distal end of the apparatus urging the arms radially outward; and -
FIGS. 7E-7H illustrate everting a graft vessel using the eversion tool of any one ofFIGS. 1-5 , whereFIG. 7E illustrates presenting the distal end portion of the graft vessel in the graft support device ofFIG. 7A ,FIG. 7F illustrates insertion of the eversion tool in the distal end portion of the graft vessel,FIG. 7C illustrates everting the distal end portion of the graft vessel with the eversion tool, andFIG. 7D illustrates extending piercing member through the distal end portion of the graft vessel after the eversion tool has been removed. - Before the present invention is described, it is to be understood that this invention is not limited to the particular embodiments or examples described herein, as such may, of course, vary. Further, when referring to the drawings, like numerals indicate like elements.
- The apparatus, systems, and methods described herein can be used to connect or anastomose tubular structures or conduits together. The tubular structures can be vascular or nonvascular structures. Thus, the apparatus, systems, and methods described herein can be used in connection with coronary artery bypass grafting procedures during which a vascular conduit or graft structure, such as a vein (e.g., a saphenous vein), artery (e.g., an internal mammary artery), or an artificial conduit or graft structure, is anastomosed to an aorta, the example target structure. They also can be used in connection with the anastomosis of internal mammary arteries to coronary arteries, and saphenous veins to coronary, femoral or popliteal arteries. The apparatus, systems, and methods described herein also can be used in connection with connecting other body lumens including nonvascular lumens, which can include, but are not intended to be limited to, the bile duct, the urethra, the urinary bladder, intestines, esophagus, stomach, and bowel.
- The ideal anastomotic connection can be created when the component vessels are arranged in a situation that provides intima-to-intima contact. Standard suturing techniques provide some degree of this attribute, but there are inconsistencies owing to, for example, variation in operator technique and vessel preparation. To ensure providing exposure of the graft vessel intima, the vessel can be everted (or cuffed). This involves manipulation of the vessel to turn a defined section inside-out to expose the internal lumen and intimal surface. This everted section can also be utilized to create a seal (or gasket) between the graft and the native vessel. The everted section can be used to form the interface at the anastomotic site that also provides a medium for desired tissue healing. One difficulty of vessel eversion arises when attempting to manually manipulate the tissue to create the everted section or cuff. As the tissue is semi-elastic, it has a tendency to resist manual eversion.
- The invention involves graft or vessel everting apparatus, systems and methods to prepare grafts and vessels for anastomosis and assist with the anastomosis. The eversion tool or apparatus of the present invention generally comprises an everting member, which comprises a flexible or pliable member or portion. The flexible or pliable member or portion can be semi-rigid and can be generally oval or circular with a closed or nearly closed turn. In other words, the flexible or pliable member or portion can be in the form of a loop. In operation, the everting member loop is inserted into one end of a graft or vessel and then manipulated to expand the graft or vessel radially outward so that the graft or vessel can be everted or draped over a vessel holder or support device, which will be described in more detail below. The everting member loop can have variable shapes and/or diameters to accommodate variously sized vessel support devices and to facilitate ease of its removal therefrom. The eversion tool also can include a handle to support the everting member.
- Referring to
FIGS. 1 , 2, 3A, and 3B, one embodiment of an eversion tool constructed in accordance with the principles of the present invention is shown and generally designated withreference numeral 100.Eversion tool 100 generally comprises an evertingmember 104, which comprises a flexible or pliable member having a portion that is in the form of a circular loop. The generally circular loop can be nearly closed or closed. It should be understood, however, the flexible and/or pliable characteristics allow the loop to be readily reshaped. One suitable material for flexible orpliable member 104 can be stainless steel wire, such as 304 series stainless steel wire, or nitinol wire. The wire typically will have a diameter ranging from about 0.002 to 0.015 inch. - In the illustrative embodiment,
eversion tool 100 includes handle 102 for supportingeverting member 104. As shown in the illustrative embodiments, handle 102 can be tubular. It also can have a collar at its distal end as shown inFIGS. 7E-G . The handle can be made from any suitable material such as a machined metal (e.g., stainless steel) or injection molded plastic. - In the embodiment illustrated in
FIGS. 3A and 3B , evertingmember 104 is slidably mounted inhandle 102. More specifically, the ends of a straight wire (e.g., a nitinol wire) can be brought together and inserted into the handle without platically deforming the wire. This facilitates adjustment of the size of the everting member loop extending fromhandle 102 by moving the ends of the wire. One can move proximally located everting member ends 104 a and 104 b relative to handle 102 to adjust the length of the elongated everting member portion extending from the distal end ofhandle 102 to adjust the loop size. InFIG. 3A , the distal ends 104 a and 104 b are in first position and inFIG. 3B they have been moved in a distal direction as shown with arrows to enlarge the loop diameter from a first diameter D1 to a second larger diameter D2. From the position shown inFIG. 3B , either one or both of the distal ends can be moved proximally to return the loop diameter toward or to DI or make the loop smaller than D1. - Referring to
FIGS. 4A and 4B another embodiment of the eversion tool is shown and generally designated withreference numeral 100′.Eversion tool 100′ is the same aseversion tool 100 with the exception that one portion of evertingmember 104 is fixedly secured to handle 102. In the example illustrated inFIGS. 4A and 4B , evertingmember 104 b is fixedly secured to handle 102. Accordingly, one can enlarge the everting member loop diameter DI as shown inFIG. 4A by moving or sliding everting member end 104 a in a distal direction as shown with the arrow inFIG. 4B to enlarge the diameter D1 to D2. One can retract everting member end 104 a to return the loop diameter toward or to D1 or reduce the loop diameter to a diameter less than D1. According to further variations, the loop can be preformed with other shapes such as oblong, oval or teardrop shapes. - Referring to
FIG. 5 , another embodiment of the eversion tool is shown and generally designated withreference numeral 100″.Eversion tool 100″ is the same aseversion tool 100 with the exception that two portions of evertingmember 104 are fixedly secured to handle 102 so that the length of the loop extending from the distal end of the handle is fixed. In the illustrative embodiment, everting member ends 104 a and 104 b can be fixedly secured to handle 102. - Referring to
FIGS. 6A-D , operation of the eversion tool will be described in conjunction with a graft support device which is schematically shown and generally indicated withreference numeral 200. In order to assist in the understanding of the operation of the eversion tool,graft support device 200 will first be described. - Anastomosis or
support device 200 is used to hold the everted graft tubular structure (e.g., graft vessel) adjacent to or in an opening formed in a target tubular structure (e.g., target vessel) to which the graft tubular structure is to be anastomosed. More specifically, the support device supports or holds the graft tubular structure in a position relative to the target tubular structure so that the graft and target tubular structure can be secured to one another with known fasteners such as sutures or surgical clips. - Anastomosis or
support device 200 comprises a proximal portion and a distal portion. The distal portion has a plurality of arms (or fingers) 206 that are configured to hold the everted portion or flap “E” of a tubular graft structure “G” as shown inFIGS. 6C and 6D . Adjacent arms are configured and arranged to form spaces, such asspaces 208, suitable for receiving surgical fasteners therethrough.Support device 200 can be described as a slotted tubular member, each slot having an open distal end and a closed end. After the support device has been positioned in the desired position and fasteners passed through a desired number of the slots through graft tubular structure and the target tubular structure, the open ends allow removal of the anastomosis or support device without disrupting the fasteners. - Anastomosis device or
support 200 can be made from any suitable plastic or metal. For example, the device can be made from ABS plastic material or stainless steel tubing such as 304 stainless steel tubing. The length of the device typically ranges from about 25 mm to about 125 mm depending on the application. In aortic applications, it typically ranges from about 25 mm to about 70 mm. The inner diameter of the tube typically ranges from about 1 mm to about 25 mm also depending on the application. For example, the inner diameter typically can vary from about 3 mm to about 6 mm when sized for an aortic anastomosis where the tube thickness can range from 0.1 mm to 2 mm. On the other hand, the tube inner diameter can be up to about 25 mm when sized for applications concerning the bowel. The tube can have any number of slots or openings, but typically will have 4 to 12 slots cut into its side or the number of arms selected and arranged to form 4 to 12 openings. The slots or openings typically extend a length of about 2 mm to about 25 mm and have a width of about 0.2 mm to about 5 mm. In aortic applications, the slot length typically can range from about 5 mm to about 25 mm and the slot width typically can range from about 0.2 mm to 2.5 mm. The desired number of sutures or clips to be used for a particular anastomosis can determine the number of spaces or slots that the anastomosis device should have. That is the number of openings can match the number desired fasteners. However, it should be understood that the number of openings need not necessarily match the number of fasteners. - The tube can be split down the side to facilitate its placement in and removal from the tubular graft structure. Regarding the former, the split allows the tube to be compressed and deformed to fit into small openings in the target vessel. On the other hand, the split can be expanded to assist in removing the graft from the device. The tube can comprise or be made of shape memory material or alloy so that the compressed split tube returns to a shape memory tubular shape that is approximately equal to or slightly larger the opening into which it is inserted. The tube construction can provide for some elastic deformation in the radial direction if radially compressed so that its annular dimension can be decreased to some degree, which can be desirable when introducing the device into an opening formed in a vessel where the opening is slightly smaller in diameter than the diameter of
device 200 in the uncompressed state. The wall thickness can be selected (e.g., reduced) to provide such elastic deformation. Other factors that can be used to achieve this effect include, but are not limited to a slot number, slit width, and material selection as would be apparent to one of skill in the art. For example, the tubular member can comprise or be made of nitinol. -
Support device 200 can be cylindrical as shown in the drawings or it can have other shapes suitable for the intended purpose. For example, it can have a rectangular or oval configuration. Other construction examples include, but are not limited to, mesh tubes, wire framed constructions, or other nonsolid wall constructions. - Referring to
FIG. 6A , tubular graft structure (e.g., graft vessel) “G” is passed betweenadjacent fingers 206 ofsupport device 200 and the distal end thereof positioned to extend distally from the support device lumen. Alternatively, the tubular graft structure can be presented through the proximal end ofsupport device 200 so that it passes along the length of the support device and extends from both the distal and proximal ends thereof.Eversion tool handle 102 so that the plane in which the everting member loop lies forms an angle of about 90 degrees with the longitudinal axis of the handle as shown inFIG. 6A . The everting member loop is adjusted to have a diameter that allows it to be readily inserted into the end of graft G. The loop diameter can be selected to be less than the inner diameter of the end of graft G as shown inFIG. 6A . The everting member loop diameter is then enlarged to mechanically expand graft G, which in this example is semi-elastic, and increase the diameter of the graft as shown inFIG. 6B . The eversion tool is then moved so that the everting member passes over the distal end of the support device, thereby mechanically draping the expanded end of the graft over the support device distal end as shown inFIG. 6C . With the graft everted oversupport device 200, the eversion tool can be retracted as shown inFIG. 6D . Optionally, one can detach one end of evertingmember 104 fromhandle 102 for easier removal (FIG. 6D ). - When
eversion tool 100′ is used with a fixed loop length, one typically does not bend the everting member to form an angle withhandle 102. In this case, the loop is inserted into the graft and pulled over the graft support device as shown inFIGS. 7E-G , which will be described in detail below. -
FIGS. 7A-D illustrate asupport device 700 that also can be used in conjunction with eversion tool orapparatus Support device 700 is described in co-pending U.S. patent application Ser. Nos. 10/340,161 and 10/340,164, both of which were filed on Jan. 10, 2003 and entitled Anastomosis Apparatus and Methods. - Anastomosis or
graft support device 700 generally includes a proximal portion and a distal portion, which includes a plurality ofarms 706 in which piercingmembers 710 can be slidably mounted. More specifically, each arm forms a pathway in which a piercingmember 710 is slidably mounted.Arms 706 can be tubular members (e.g., hypotubes) each having a lumen through which a piercingmember 706 can slide. -
Arms 706 are biased radially inward and have outer diameters that can range from 0.5 mm to 2 mm, for example, in aortic applications. In the illustrative embodiment,anastomosis apparatus 700 includes a mandrel or slide 722 for radially expanding the piercing member carrying or supportarms 706. - Each
arm 706 has a proximal end secured to tubular member orarm support 720 which tapers so that the annular dimension of the arms, taken collectively, progressively decreases in the distal direction when theslide 722 is in a retracted position adjacent toarm support 720 as shown inFIG. 7A . The arms can be secured in circumferentially spaced longitudinal grooves formed inarm support 720 by gluing or other suitable means. The arms also extend along longitudinal grooves formed in mandrel orslide 722. Actuator orplunger 718 extends through the device with its end secured to mandrel or slide 722 so that when the pusher is moved forwardly, it pushes the mandrel or slide 722 distally and radially expands the arms. After a graft is everted over the distal ends of the arms as will be described below, it can be desirable to radially expand the arms when graft holder orsupport 700 is positioned in an opening in a target tubular structure (e.g., target vessel) to which the tubular graft structure (e.g., graft vessel) is to be anatomosed. The radial expansion of the arms can enhance or form a seal between the graft and the target tubular structure (e.g., an aorta). - Referring to
FIGS. 7C and 7D , apparatus ordevice 700 further includes piercingmembers 710, which are slidably mounted inarms 706. Piercingmembers 710 haveproximal portions 710 a anddistal portions 710 b. Piercingmembers 710 extend fromarms 706 proximally toward cylindrical piercingmember support 721 whereproximal portions 710 a are secured in grooves formed in cylindrical piercingmember support 721.Support 721 is slidably mounted on actuator orpusher 718 and secured to cylindrical knob orfinger grip 714 by fastener or screw 716 (FIG. 7B ). Whenknob 714 is pushed forwardly in a distal direction, the piercing members are extended as shown inFIGS. 7C and 7D . Moving theknob 714 proximally retracts the piercing members as shown inFIG. 7A . Housing ortubular body 712 can have alongitudinal slot 717 through which screw 716 can slide so thatknob 714 can move independently fromhousing 712. - The radius of curvature of the memory shaped
distal portions 710 b of the piercing members can vary. For example, a larger radius of curvature may be desired if the user wants to insert part of the device into the opening in the target structure or vessel to which the graft is to be anastomosed. On the other hand, a smaller radius of curvature may be desired if the user wants to tack the device down around the opening in the target structure or vessel, thereby seating the device on the outer wall and covering the opening with the graft. -
Distal portions 710 b have the desired memory shape to pierce the graft and vessel to which the graft is to be anastomosed when the piercing members are advanced. In the illustrative embodiment, the piercing members comprise shape memory material so that thedistal portions 710 b can be provided with a hook configured memory shape, which is one suitable shape for holding the graft and vessel together during the anastomosis. Thus, the piercing members can be made of nitinol wire and the distal portions provided with the desired memory shape as is known in the art so that they return to their memory shape when in an unbiased state (e.g., extended from arms 706). In other words, the shape memory alloy distal portions exhibit pseudoelastic (superelastic) behavior. - Referring to
FIGS. 7E-G , eversion of a graft over the distal end portion of support member orapparatus 700 using any one of theeversion tools apparatus 700 with the distal end of graft structure G extending from the distal end of the support device as shown inFIG. 7E . The everting member loop ofeversion tool 100 is introduced through the distal end of the graft structure and inserted into the graft lumen shown inFIG. 7F . The diameter of the everting member or loop can be increased as described above in connection withembodiments arms 706, thereby everting graft structure G over the support member distal end portion and forming everted portion E with the intimal surface of the graft lumen exposed and facing radially outward. In this manner the graft is prepared for an anastomosis where an intima-to-intima connection can be readily achieved. The support device can be positioned in an opening formed in the target tubular structure and the piercing members extended as shown inFIG. 7H to hold the graft and target tubular structures together, while fasteners are used to secure the graft and target structures together. - More specifically, after the surgeon cuts a hole or opening in the target tubular structure or vessel (e.g., the aorta) using a scalpel and an aorta cutting device or punch, the surgeon covers the hole with either a finger or other suitable tool. The distal portion of the support device and the portion of the graft everted thereover are positioned in the vessel opening. The distal portions of the piercing members are extended and the mandrel is moved distally to expand the arms and everted graft against the tissue surrounding the opening so as to form a seal therewith. In other words, the arms can be expanded to urge the everted graft against the tissue surrounding the target vessel opening to seal the connection between the graft and target vessel. After the fasteners have been placed to connect the graft and target tubular structures, the piercing members are retracted and
anastomosis device 700 pulled off of the graft and target structures. Additional fasteners or clips can be placed at the connection, if any blood appears to be seeping out from the graft and target vessel. - Any fastener can be used to secure the tubular graft and target structures together. Examples of suitable fasteners include conventional sutures and surgical clips such as the surgical clips disclosed in U.S. Pat. Nos. 5,972,024 to Northrup, et al., 6,607,541 to Gardiner, et al., 6,514,265 to Ho, et al., U.S. Patent Publication No. 2002-0010490 of U.S. patent application Ser. No. 09/260,623 filed Mar. 1, 1999 and entitled Tissue Connector Methods and Apparatus and U.S. patent application Ser. No. 09/090,305 filed Jun. 3, 1998 and entitled Tissue Connector Apparatus and Methods.
- Variations and modifications of the devices and methods disclosed herein will be readily apparent to persons skilled in the art. As such, it should be understood that the foregoing detailed description and the accompanying illustrations, are made for purposes of clarity and understanding, and are not intended to limit the scope of the invention, which is defined by the claims appended hereto.
Claims (14)
1. Surgical eversion apparatus for preparing a conduit for anastomosis in a human patient using a device with multiple piercing members, said eversion apparatus comprising a handle coupled to an everting member having a loop shaped portion adapted to be inserted into an end portion of a conduit from a human patient and configured to fold a portion of the conduit over itself when it is moved away from the conduit end portion and along the conduit while a portion of the conduit is held fixed relative thereto, wherein said handle defines a major longitudinal axis and further wherein said eversion apparatus is configured to provide a first state in which said loop shaped portion extends from said handle in a plane parallel with said major longitudinal axis.
2. The eversion apparatus of claim 1 wherein said everting member comprises a flexible member having two ends, said two ends being movable relative to said handle and portions of said flexible member being slidably mounted to said handle.
3. The eversion apparatus of claim 1 wherein said everting member comprises a flexible member having two ends, one of said ends being movable relative to said handle, the other one of said two ends being fixedly secured to said handle.
4. The eversion apparatus of claim 1 wherein said everting member comprises a flexible member having two ends, both of said ends being fixedly attached to said handle.
5. The eversion apparatus of any one of claims 2 -4 wherein said flexible member comprises a pliable wire.
6. The eversion apparatus of claim 1 wherein said loop shaped portion has an adjustable diameter.
7. The eversion apparatus of claim 1 , wherein said overting member is bendable from said first state such that said eversion apparatus is configured to be transitionable to a second state in which said loop shaped portion extends from said handle in a plane forming an angle of about 90 degrees with said major longitudinal axis.
8. A vessel eversion system for preparing a vessel for anastomosis in a human patient, said vessel eversion system comprising: a vessel support device having a proximal end and a distal end forming a plurality of piercing members; and an everting apparatus comprising an everting member, said everting member having a loop shaped portion adapted to be inserted into a portion of a vessel to be prepared for an anastomosis in a human patient and evert the portion of the vessel over said plurality of piercing members when said vessel is coupled to said support device with an end portion thereof extending from said distal end of said support device.
9. The vessel eversion system of claim 8 wherein said everting apparatus includes a handle and said everting member is coupled to said handle.
10. The vessel eversion system of claim 9 wherein said everting member comprises a flexible member having two ends, said two ends being movable relative to said handle and portions of said flexible member being slidably mounted to said handle.
11. The vessel eversion system of claim 9 wherein said everting member comprises a flexible member having two ends, one of said ends being movable relative to said handle, the other one of said two ends being fixedly secured to said handle.
12. The vessel eversion system of claim 9 wherein said everting member comprises a flexible member having two ends, both of said ends being fixedly attached to said handle.
13. The vessel eversion system of any one of claims 10 -12 wherein said flexible member comprises a pliable wire.
14. The vessel eversion system of claim 8 wherein said loop shaped portion has an adjustable diameter.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/235,445 US20090240265A1 (en) | 2003-08-22 | 2008-09-22 | Eversion apparatus and methods |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/646,254 US20050043749A1 (en) | 2003-08-22 | 2003-08-22 | Eversion apparatus and methods |
US12/235,445 US20090240265A1 (en) | 2003-08-22 | 2008-09-22 | Eversion apparatus and methods |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/646,254 Continuation US20050043749A1 (en) | 2003-08-22 | 2003-08-22 | Eversion apparatus and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
US20090240265A1 true US20090240265A1 (en) | 2009-09-24 |
Family
ID=34194487
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/646,254 Abandoned US20050043749A1 (en) | 2003-08-22 | 2003-08-22 | Eversion apparatus and methods |
US11/521,152 Expired - Fee Related US8029519B2 (en) | 2003-08-22 | 2006-09-14 | Eversion apparatus and methods |
US12/235,445 Abandoned US20090240265A1 (en) | 2003-08-22 | 2008-09-22 | Eversion apparatus and methods |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/646,254 Abandoned US20050043749A1 (en) | 2003-08-22 | 2003-08-22 | Eversion apparatus and methods |
US11/521,152 Expired - Fee Related US8029519B2 (en) | 2003-08-22 | 2006-09-14 | Eversion apparatus and methods |
Country Status (1)
Country | Link |
---|---|
US (3) | US20050043749A1 (en) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6613059B2 (en) | 1999-03-01 | 2003-09-02 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
US6945980B2 (en) * | 1998-06-03 | 2005-09-20 | Medtronic, Inc. | Multiple loop tissue connector apparatus and methods |
US6641593B1 (en) | 1998-06-03 | 2003-11-04 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
US6607541B1 (en) * | 1998-06-03 | 2003-08-19 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
US8118822B2 (en) * | 1999-03-01 | 2012-02-21 | Medtronic, Inc. | Bridge clip tissue connector apparatus and methods |
US6695859B1 (en) * | 1999-04-05 | 2004-02-24 | Coalescent Surgical, Inc. | Apparatus and methods for anastomosis |
US8529583B1 (en) | 1999-09-03 | 2013-09-10 | Medtronic, Inc. | Surgical clip removal apparatus |
US6926730B1 (en) * | 2000-10-10 | 2005-08-09 | Medtronic, Inc. | Minimally invasive valve repair procedure and apparatus |
US6551332B1 (en) | 2000-03-31 | 2003-04-22 | Coalescent Surgical, Inc. | Multiple bias surgical fastener |
US20060293701A1 (en) * | 2001-05-02 | 2006-12-28 | Medtronic, Inc. | Self-closing surgical clip for tissue |
US7201771B2 (en) | 2001-12-27 | 2007-04-10 | Arbor Surgical Technologies, Inc. | Bioprosthetic heart valve |
US20030199974A1 (en) * | 2002-04-18 | 2003-10-23 | Coalescent Surgical, Inc. | Annuloplasty apparatus and methods |
US7959674B2 (en) | 2002-07-16 | 2011-06-14 | Medtronic, Inc. | Suture locking assembly and method of use |
US7155273B2 (en) * | 2002-07-29 | 2006-12-26 | Taylor Geoffrey L | Blanching response pressure sore detector apparatus and method |
US8066724B2 (en) | 2002-09-12 | 2011-11-29 | Medtronic, Inc. | Anastomosis apparatus and methods |
US8105345B2 (en) * | 2002-10-04 | 2012-01-31 | Medtronic, Inc. | Anastomosis apparatus and methods |
US9060844B2 (en) | 2002-11-01 | 2015-06-23 | Valentx, Inc. | Apparatus and methods for treatment of morbid obesity |
US8551162B2 (en) | 2002-12-20 | 2013-10-08 | Medtronic, Inc. | Biologically implantable prosthesis |
US20050075659A1 (en) * | 2003-03-30 | 2005-04-07 | Fidel Realyvasquez | Apparatus and methods for minimally invasive valve surgery |
US7182769B2 (en) * | 2003-07-25 | 2007-02-27 | Medtronic, Inc. | Sealing clip, delivery systems, and methods |
US8021421B2 (en) | 2003-08-22 | 2011-09-20 | Medtronic, Inc. | Prosthesis heart valve fixturing device |
US20050043749A1 (en) * | 2003-08-22 | 2005-02-24 | Coalescent Surgical, Inc. | Eversion apparatus and methods |
US8394114B2 (en) | 2003-09-26 | 2013-03-12 | Medtronic, Inc. | Surgical connection apparatus and methods |
US7556647B2 (en) * | 2003-10-08 | 2009-07-07 | Arbor Surgical Technologies, Inc. | Attachment device and methods of using the same |
US7879047B2 (en) | 2003-12-10 | 2011-02-01 | Medtronic, Inc. | Surgical connection apparatus and methods |
US7763037B2 (en) * | 2005-03-18 | 2010-07-27 | Castlewood Surgical, Inc. | System and method for attaching a vein, an artery, or a tube in a vascular environment |
US7513909B2 (en) | 2005-04-08 | 2009-04-07 | Arbor Surgical Technologies, Inc. | Two-piece prosthetic valves with snap-in connection and methods for use |
WO2006130505A2 (en) | 2005-05-27 | 2006-12-07 | Arbor Surgical Technologies, Inc. | Gasket with collar for prosthetic heart valves and methods for using them |
US7967857B2 (en) | 2006-01-27 | 2011-06-28 | Medtronic, Inc. | Gasket with spring collar for prosthetic heart valves and methods for making and using them |
WO2007106755A1 (en) * | 2006-03-10 | 2007-09-20 | Arbor Surgical Technologies, Inc. | Valve introducers and methods for making and using them |
EP2023860A2 (en) | 2006-04-29 | 2009-02-18 | Arbor Surgical Technologies, Inc. | Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them |
US8118774B2 (en) * | 2006-09-25 | 2012-02-21 | Valentx, Inc. | Toposcopic access and delivery devices |
US7914552B2 (en) * | 2006-11-09 | 2011-03-29 | Ethicon Endo-Surgery, Inc. | Method of performing an end-to-end anastomosis using a stent and an adhesive |
WO2008067384A2 (en) * | 2006-11-30 | 2008-06-05 | Wilson-Cook Medical, Inc. | Visceral anchors for purse-string closure of perforations |
WO2008086287A2 (en) * | 2007-01-05 | 2008-07-17 | Medtronic, Inc. | Anastomosis systems and methods |
US20080262597A1 (en) * | 2007-04-17 | 2008-10-23 | Medtronic Vascular, Inc. | Prosthesis Fixation Apparatus and Methods |
US8486094B2 (en) | 2007-08-21 | 2013-07-16 | Castlewood Surgical, Inc. | System and method for providing an obturator for enhanced directional capabilities in a vascular environment |
US8728101B2 (en) * | 2007-08-21 | 2014-05-20 | Castlewood Surgical, Inc. | System and method for providing an obturator for enhanced directional capabilities in a vascular environment |
US20090307066A1 (en) * | 2007-12-11 | 2009-12-10 | Interactive Marketing, Incorporate | Coupon dispensing methods and systems |
US8177836B2 (en) * | 2008-03-10 | 2012-05-15 | Medtronic, Inc. | Apparatus and methods for minimally invasive valve repair |
US20090270912A1 (en) * | 2008-04-23 | 2009-10-29 | Wilson-Cook Medical Inc. | Tacking device |
US8900250B2 (en) * | 2008-08-19 | 2014-12-02 | Cook Medical Technologies, LLC | Apparatus and methods for removing lymph nodes or anchoring into tissue during a translumenal procedure |
US8192461B2 (en) * | 2008-09-11 | 2012-06-05 | Cook Medical Technologies Llc | Methods for facilitating closure of a bodily opening using one or more tacking devices |
US20100076376A1 (en) * | 2008-09-19 | 2010-03-25 | Sorin Biomedica Cardio S. r. l. | Surgical tool for vascular exposure and access |
EP2384149B1 (en) * | 2008-12-05 | 2015-12-02 | Cook Medical Technologies LLC | Tissue anchors for purse-string closure of perforations |
US8500760B2 (en) | 2008-12-09 | 2013-08-06 | Cook Medical Technologies Llc | Retractable tacking device |
EP2373224A1 (en) * | 2008-12-09 | 2011-10-12 | Wilson-Cook Medical Inc. | Apparatus and methods for controlled release of tacking devices |
WO2010080386A2 (en) * | 2008-12-19 | 2010-07-15 | Wilson-Cook Medical Inc. | Clip devices and methods of delivery and deployment |
JP2012512715A (en) * | 2008-12-19 | 2012-06-07 | クック メディカル テクノロジーズ エルエルシー | A tacking device of varying thickness and method of delivery and deployment thereof |
CA2757494C (en) * | 2009-04-03 | 2013-11-12 | Cook Medical Technologies Llc | Medical devices, systems, and methods for rapid deployment and fixation of tissue anchors |
WO2010115072A1 (en) | 2009-04-03 | 2010-10-07 | Wilson-Cook Medical, Inc. | Tissue anchors and medical devices for rapid deployment of tissue anchors |
US8518060B2 (en) | 2009-04-09 | 2013-08-27 | Medtronic, Inc. | Medical clip with radial tines, system and method of using same |
US8668704B2 (en) | 2009-04-24 | 2014-03-11 | Medtronic, Inc. | Medical clip with tines, system and method of using same |
CA2763133A1 (en) * | 2009-05-28 | 2010-12-02 | Cook Medical Technologies Llc | Tacking device and methods of deployment |
US8740970B2 (en) * | 2009-12-02 | 2014-06-03 | Castlewood Surgical, Inc. | System and method for attaching a vessel in a vascular environment |
CN102247186A (en) * | 2011-04-12 | 2011-11-23 | 西安交通大学 | Auxiliary device suitable for vascular magnetic anastomosis rings |
US9681975B2 (en) | 2012-05-31 | 2017-06-20 | Valentx, Inc. | Devices and methods for gastrointestinal bypass |
US9451960B2 (en) | 2012-05-31 | 2016-09-27 | Valentx, Inc. | Devices and methods for gastrointestinal bypass |
US9566181B2 (en) | 2012-05-31 | 2017-02-14 | Valentx, Inc. | Devices and methods for gastrointestinal bypass |
US9757264B2 (en) | 2013-03-13 | 2017-09-12 | Valentx, Inc. | Devices and methods for gastrointestinal bypass |
Citations (100)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US424518A (en) * | 1890-04-01 | Needle-threader | ||
US1087186A (en) * | 1909-03-22 | 1914-02-17 | Socrates Scholfield | Illustrative educational device. |
US1167014A (en) * | 1915-06-25 | 1916-01-04 | William R O'brien | Veterinary surgical instrument. |
US2042403A (en) * | 1935-02-27 | 1936-05-26 | Hrivnak Andrew | Needle threader |
US3082426A (en) * | 1960-06-17 | 1963-03-26 | George Oliver Halsted | Surgical stapling device |
US3404707A (en) * | 1966-06-29 | 1968-10-08 | Henry Heckmann | Thread pulling needle devices |
US3570497A (en) * | 1969-01-16 | 1971-03-16 | Gerald M Lemole | Suture apparatus and methods |
US3638654A (en) * | 1969-07-11 | 1972-02-01 | Uche Akuba | Suturing instrument |
US4006747A (en) * | 1975-04-23 | 1977-02-08 | Ethicon, Inc. | Surgical method |
US4073179A (en) * | 1976-06-01 | 1978-02-14 | Codman & Shurtleff, Inc. | Clip removing device |
US4102478A (en) * | 1976-12-27 | 1978-07-25 | Constantin Samoilov | Needle threader |
US4140125A (en) * | 1976-02-25 | 1979-02-20 | Med-Pro, Ltd. | Surgical tape device |
US4185636A (en) * | 1977-12-29 | 1980-01-29 | Albert Einstein College Of Medicine Of Yeshiva University | Suture organizer, prosthetic device holder, and related surgical procedures |
US4192315A (en) * | 1976-12-23 | 1980-03-11 | Aesculap-Werke Aktiengesellschaft Vormals Jetter & Scheerer | Clip for surgical purposes |
US4243048A (en) * | 1976-09-21 | 1981-01-06 | Jim Zegeer | Biopsy device |
US4366819A (en) * | 1980-11-17 | 1983-01-04 | Kaster Robert L | Anastomotic fitting |
US4492229A (en) * | 1982-09-03 | 1985-01-08 | Grunwald Ronald P | Suture guide holder |
US4523592A (en) * | 1983-04-25 | 1985-06-18 | Rollin K. Daniel P.S.C. | Anastomotic coupling means capable of end-to-end and end-to-side anastomosis |
US4576605A (en) * | 1985-03-01 | 1986-03-18 | Nauchno-Issledovatelsky Institut Khirurgii Imeni A.V. Vishnevskogo | Cardiac valve prosthesis |
US4637380A (en) * | 1985-06-24 | 1987-01-20 | Orejola Wilmo C | Surgical wound closures |
US4641652A (en) * | 1984-04-12 | 1987-02-10 | Richard Wolf Gmbh | Applicator for tying sewing threads |
US4719924A (en) * | 1986-09-09 | 1988-01-19 | C. R. Bard, Inc. | Small diameter steerable guidewire with adjustable tip |
US4719917A (en) * | 1987-02-17 | 1988-01-19 | Minnesota Mining And Manufacturing Company | Surgical staple |
US4730615A (en) * | 1986-03-03 | 1988-03-15 | Pfizer Hospital Products Group, Inc. | Sternum closure device |
US4732151A (en) * | 1986-10-08 | 1988-03-22 | Patent Research & Development Corp. | Low trauma suturing |
US4779616A (en) * | 1986-02-04 | 1988-10-25 | Johnson Lanny L | Surgical suture-snagging method |
US4809695A (en) * | 1981-10-21 | 1989-03-07 | Owen M. Gwathmey | Suturing assembly and method |
US4890615A (en) * | 1987-11-05 | 1990-01-02 | Concept, Inc. | Arthroscopic suturing instrument |
US4896668A (en) * | 1986-04-10 | 1990-01-30 | Peters | Plate set for osteal fixation, equipped with suture strands |
US4899744A (en) * | 1988-12-15 | 1990-02-13 | Tatsuo Fujitsuka | Apparatus for anastomosing digestive tract |
US4901721A (en) * | 1988-08-02 | 1990-02-20 | Hakki Samir I | Suturing device |
US5088692A (en) * | 1990-09-04 | 1992-02-18 | Weiler Raywood C | Heavy duty staple remover |
US5100421A (en) * | 1991-02-05 | 1992-03-31 | Cyprus Endosurgical Tools, Inc. | Christoudias curved needle suture assembly |
US5100418A (en) * | 1987-05-14 | 1992-03-31 | Inbae Yoon | Suture tie device system and applicator therefor |
US5178634A (en) * | 1989-03-31 | 1993-01-12 | Wilson Ramos Martinez | Aortic valved tubes for human implants |
US5192294A (en) * | 1989-05-02 | 1993-03-09 | Blake Joseph W Iii | Disposable vascular punch |
US5196022A (en) * | 1988-12-12 | 1993-03-23 | Ethicon, Inc. | Ligature system for use in endoscopic surgery, ligature and handling instrument for said system |
US5282825A (en) * | 1993-06-02 | 1994-02-01 | Muck Kin C | Surgical ligaturing and animal restraining device |
US5290289A (en) * | 1990-05-22 | 1994-03-01 | Sanders Albert E | Nitinol spinal instrumentation and method for surgically treating scoliosis |
US5382259A (en) * | 1992-10-26 | 1995-01-17 | Target Therapeutics, Inc. | Vasoocclusion coil with attached tubular woven or braided fibrous covering |
US5383904A (en) * | 1992-10-13 | 1995-01-24 | United States Surgical Corporation | Stiffened surgical device |
US5387227A (en) * | 1992-09-10 | 1995-02-07 | Grice; O. Drew | Method for use of a laparo-suture needle |
US5480405A (en) * | 1987-05-14 | 1996-01-02 | Yoon; Inbae | Anchor applier instrument for use in suturing tissue |
US5486187A (en) * | 1994-01-04 | 1996-01-23 | Schenck; Robert R. | Anastomosis device and method |
US5486197A (en) * | 1994-03-24 | 1996-01-23 | Ethicon, Inc. | Two-piece suture anchor with barbs |
US5488958A (en) * | 1992-11-09 | 1996-02-06 | Vance Products Incorporated | Surgical cutting instrument for coring tissue affixed thereto |
US5496334A (en) * | 1993-03-31 | 1996-03-05 | J. Stro/ bel & Sohne GmbH & Co. | Suturing apparatus |
US5499990A (en) * | 1992-05-23 | 1996-03-19 | Forschungszentrum Karlsruhe Gmbh | Suturing instrument |
US5500000A (en) * | 1993-07-01 | 1996-03-19 | United States Surgical Corporation | Soft tissue repair system and method |
US5501692A (en) * | 1994-01-28 | 1996-03-26 | Riza; Erol D. | Laparoscopic suture snare |
US5707362A (en) * | 1992-04-15 | 1998-01-13 | Yoon; Inbae | Penetrating instrument having an expandable anchoring portion for triggering protrusion of a safety member and/or retraction of a penetrating member |
US5707380A (en) * | 1996-07-23 | 1998-01-13 | United States Surgical Corporation | Anastomosis instrument and method |
US5709695A (en) * | 1994-08-10 | 1998-01-20 | Segmed, Inc. | Apparatus for reducing the circumference of a vascular structure |
US5709693A (en) * | 1996-02-20 | 1998-01-20 | Cardiothoracic System, Inc. | Stitcher |
US5715987A (en) * | 1994-04-05 | 1998-02-10 | Tracor Incorporated | Constant width, adjustable grip, staple apparatus and method |
US5720755A (en) * | 1995-01-18 | 1998-02-24 | Dakov; Pepi | Tubular suturing device and methods of use |
US5725542A (en) * | 1995-03-09 | 1998-03-10 | Yoon; Inbae | Multifunctional spring clips and cartridges and applicators therefor |
US5725539A (en) * | 1993-12-01 | 1998-03-10 | Klinikum Der Albert-Ludwigs-Universitat Freiburg | Surgical instrument used to clamp a vessel or the like |
US5728135A (en) * | 1996-02-09 | 1998-03-17 | Ethicon, Inc. | Stiffened suture for use in a suturing device |
US5732872A (en) * | 1994-06-17 | 1998-03-31 | Heartport, Inc. | Surgical stapling instrument |
US5855614A (en) * | 1993-02-22 | 1999-01-05 | Heartport, Inc. | Method and apparatus for thoracoscopic intracardiac procedures |
US5868702A (en) * | 1991-07-16 | 1999-02-09 | Heartport, Inc. | System for cardiac procedures |
US5868763A (en) * | 1996-09-16 | 1999-02-09 | Guidant Corporation | Means and methods for performing an anastomosis |
US5871528A (en) * | 1996-06-28 | 1999-02-16 | Medtronic, Inc. | Temporary bipolar heart wire |
US5879371A (en) * | 1997-01-09 | 1999-03-09 | Elective Vascular Interventions, Inc. | Ferruled loop surgical fasteners, instruments, and methods for minimally invasive vascular and endoscopic surgery |
US5881943A (en) * | 1994-06-17 | 1999-03-16 | Heartport, Inc. | Surgical anastomosis apparatus and method thereof |
US6010531A (en) * | 1993-02-22 | 2000-01-04 | Heartport, Inc. | Less-invasive devices and methods for cardiac valve surgery |
US6013084A (en) * | 1995-06-30 | 2000-01-11 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils (II) |
US6022367A (en) * | 1997-06-18 | 2000-02-08 | United States Surgical | Surgical apparatus for forming a hole in a blood vessel |
US6024748A (en) * | 1996-07-23 | 2000-02-15 | United States Surgical Corporation | Singleshot anastomosis instrument with detachable loading unit and method |
US6033419A (en) * | 1998-05-15 | 2000-03-07 | Sulzer Carbomedics Inc. | Apparatus and method for cutting a heart valve annulus |
US6032849A (en) * | 1995-08-28 | 2000-03-07 | United States Surgical | Surgical stapler |
US6036699A (en) * | 1992-12-10 | 2000-03-14 | Perclose, Inc. | Device and method for suturing tissue |
US6036710A (en) * | 1996-10-04 | 2000-03-14 | United States Surgical | Apparatus for formation of a hole in a blood vessel |
US6036703A (en) * | 1998-02-06 | 2000-03-14 | Ethicon Endo-Surgery Inc. | Method and apparatus for establishing anastomotic passageways |
US6042607A (en) * | 1996-02-23 | 2000-03-28 | Cardiovascular Technologies Llc | Means and method of replacing a heart valve in a minimally invasive manner |
US6171320B1 (en) * | 1996-12-25 | 2001-01-09 | Niti Alloys Technologies Ltd. | Surgical clip |
US6171321B1 (en) * | 1995-02-24 | 2001-01-09 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US6176864B1 (en) * | 1998-03-09 | 2001-01-23 | Corvascular, Inc. | Anastomosis device and method |
US6179840B1 (en) * | 1999-07-23 | 2001-01-30 | Ethicon, Inc. | Graft fixation device and method |
US6179849B1 (en) * | 1999-06-10 | 2001-01-30 | Vascular Innovations, Inc. | Sutureless closure for connecting a bypass graft to a target vessel |
US6179848B1 (en) * | 1996-07-24 | 2001-01-30 | Jan Otto Solem | Anastomotic fitting |
US6183512B1 (en) * | 1999-04-16 | 2001-02-06 | Edwards Lifesciences Corporation | Flexible annuloplasty system |
US6190373B1 (en) * | 1992-11-13 | 2001-02-20 | Scimed Life Systems, Inc. | Axially detachable embolic coil assembly |
US6193733B1 (en) * | 1997-06-20 | 2001-02-27 | Boston Scientific Corporation | Hemostatic clips |
US6193734B1 (en) * | 1998-01-23 | 2001-02-27 | Heartport, Inc. | System for performing vascular anastomoses |
US6197037B1 (en) * | 1999-07-29 | 2001-03-06 | John Hunter Hair | Surgical fastener for joining adjacent bone portions |
US20020010490A1 (en) * | 1999-03-01 | 2002-01-24 | Laurent Schaller | Tissue connector apparatus and methods |
US6346074B1 (en) * | 1993-02-22 | 2002-02-12 | Heartport, Inc. | Devices for less invasive intracardiac interventions |
US6350269B1 (en) * | 1999-03-01 | 2002-02-26 | Apollo Camera, L.L.C. | Ligation clip and clip applier |
US6514265B2 (en) * | 1999-03-01 | 2003-02-04 | Coalescent Surgical, Inc. | Tissue connector apparatus with cable release |
US6517558B2 (en) * | 1999-01-15 | 2003-02-11 | Ventrica, Inc. | Methods and devices for forming vascular anastomoses |
US6524338B1 (en) * | 2000-08-25 | 2003-02-25 | Steven R. Gundry | Method and apparatus for stapling an annuloplasty band in-situ |
US6682540B1 (en) * | 1999-11-05 | 2004-01-27 | Onux Medical, Inc. | Apparatus and method for placing multiple sutures |
US6695859B1 (en) * | 1999-04-05 | 2004-02-24 | Coalescent Surgical, Inc. | Apparatus and methods for anastomosis |
US20050004582A1 (en) * | 2002-12-16 | 2005-01-06 | Edoga John K. | Endovascular stapler |
US20050021054A1 (en) * | 2003-07-25 | 2005-01-27 | Coalescent Surgical, Inc. | Sealing clip, delivery systems, and methods |
US20050043749A1 (en) * | 2003-08-22 | 2005-02-24 | Coalescent Surgical, Inc. | Eversion apparatus and methods |
US20060004389A1 (en) * | 1998-06-03 | 2006-01-05 | Medtronic, Inc. | Multiple loop tissue connector apparatus and methods |
US20070027461A1 (en) * | 1998-06-03 | 2007-02-01 | Barry Gardiner | Tissue connector apparatus and methods |
Family Cites Families (432)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US43098A (en) | 1864-06-14 | Improvement in suture-instruments | ||
US2715486A (en) | 1955-08-16 | Fast-threading needls with trailing flexible link | ||
US636728A (en) | 1899-05-24 | 1899-11-07 | George J Kindel | Tape-needle. |
US655190A (en) | 1899-11-27 | 1900-08-07 | Louis Bramson | Suturating instrument. |
US1539221A (en) | 1923-10-30 | 1925-05-26 | Tennant John William | Welder's rod holder |
US1583271A (en) | 1925-01-14 | 1926-05-04 | Biro Ladislaus | Surgical instrument |
US1625602A (en) | 1926-04-06 | 1927-04-19 | Harold G Gould | Surgical appliance |
US1867624A (en) | 1930-04-01 | 1932-07-19 | Memorial Hospital For The Trea | Device for obtaining biopsy specimens |
US2201610A (en) | 1938-05-20 | 1940-05-21 | Jr James C Dawson | Wound clip |
US2240330A (en) | 1938-07-11 | 1941-04-29 | Andrew B Flagg | Surgical needle or the like |
US2256382A (en) | 1939-03-06 | 1941-09-16 | Edward H Kruse | Surgical ligature applicator |
US2264679A (en) | 1940-10-29 | 1941-12-02 | Ravel Vincent Marvin | Surgical instrument |
US2430293A (en) | 1944-10-21 | 1947-11-04 | John N M Howells | Means for applying fastening devices |
US2413142A (en) | 1945-06-11 | 1946-12-24 | Edwin M Jones | Suturing assembly and method |
US2516710A (en) | 1947-05-12 | 1950-07-25 | Delfino P Mascolo | Double point surgical needle |
US2505358A (en) | 1949-04-20 | 1950-04-25 | Sklar Mfg Co Inc J | Double-cutting biopsy bistoury |
US2890519A (en) | 1955-08-01 | 1959-06-16 | Storz Instr Co | Surgical spring clip forceps |
US2940452A (en) | 1958-11-07 | 1960-06-14 | Ca Nat Research Council | Vascular evertor |
US3055689A (en) | 1960-06-29 | 1962-09-25 | Clarence H Jorgensen | Holding device for doors and the like |
US3057355A (en) | 1960-07-08 | 1962-10-09 | Canadian Patents Dev | Vascular everter |
US3150379A (en) | 1962-03-01 | 1964-09-29 | Ernest C Wood | Single clip disposable applicator |
US3143742A (en) | 1963-03-19 | 1964-08-11 | Surgitool Inc | Prosthetic sutureless heart valve |
US3180337A (en) | 1963-04-25 | 1965-04-27 | Ca Nat Research Council | Vascular everting device |
US3249104A (en) | 1963-06-21 | 1966-05-03 | George J Hohnstein | Surgical needle |
GB1021589A (en) | 1963-12-05 | 1966-03-02 | Down Brothers And Mayer And Ph | Improvements in and relating to clamping devices |
US3547103A (en) | 1965-10-29 | 1970-12-15 | William A Cook | Coil spring guide |
US3452740A (en) | 1966-05-31 | 1969-07-01 | Us Catheter & Instr Corp | Spring guide manipulator |
US3506012A (en) | 1967-08-01 | 1970-04-14 | Ivan E Brown | Polyp clamp and applier therefor |
US3509882A (en) | 1967-09-18 | 1970-05-05 | American Hospital Supply Corp | Parallel jaw spring clip and applicator |
NL143127B (en) | 1969-02-04 | 1974-09-16 | Rhone Poulenc Sa | REINFORCEMENT DEVICE FOR A DEFECTIVE HEART VALVE. |
US3674304A (en) * | 1970-01-02 | 1972-07-04 | Raymond W Swanson | Releasable automatic fastener for a truck stake and like |
US3608095A (en) | 1970-03-05 | 1971-09-28 | Federal Tool Eng Co | Method of fixing hair pieces to scalps |
USRE27391E (en) | 1970-10-12 | 1972-06-20 | Connector for holding articles together | |
US3802438A (en) | 1972-03-31 | 1974-04-09 | Technibiotics | Surgical instrument |
US3753438A (en) | 1972-04-25 | 1973-08-21 | E Wood | Suture clip |
US3776237A (en) | 1972-05-11 | 1973-12-04 | Tecna Corp | Surgical tool and method of providing a surgical opening |
US3874388A (en) | 1973-02-12 | 1975-04-01 | Ochsner Med Found Alton | Shunt defect closure system |
US3825009A (en) | 1973-03-19 | 1974-07-23 | J Williams | Method of surgically repairing damaged ear drums |
US3875648A (en) | 1973-04-04 | 1975-04-08 | Dennison Mfg Co | Fastener attachment apparatus and method |
GB1413191A (en) | 1973-07-04 | 1975-11-12 | Vnii Khirurgicheskoi Apparatur | Device for the eversion of hollow organs and vascular stapling instrument incorporating same |
US3837345A (en) | 1973-08-31 | 1974-09-24 | A Matar | Venous valve snipper |
US3910281A (en) | 1973-10-09 | 1975-10-07 | Bio Medicus Inc | Suture anchor |
JPS5320957Y2 (en) | 1973-11-14 | 1978-06-01 | ||
US3905403A (en) | 1973-12-26 | 1975-09-16 | Kuhlman Corp | Methods of manufacturing dual interlocked safety spring assemblies |
US3976079A (en) | 1974-08-01 | 1976-08-24 | Samuels Peter B | Securing devices for sutures |
US4129059A (en) | 1974-11-07 | 1978-12-12 | Eck William F Van | Staple-type fastener |
US4018228A (en) | 1975-02-24 | 1977-04-19 | Goosen Carl C | Surgical punch apparatus |
US4038725A (en) | 1975-03-20 | 1977-08-02 | Monarch Marking Systems, Inc. | Fastener and method of using same |
SU566574A1 (en) | 1975-05-04 | 1977-07-30 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Apparatus for applying linear agraffe suture on organs and tissue |
US3995619A (en) | 1975-10-14 | 1976-12-07 | Glatzer Stephen G | Combination subcutaneous suture remover, biopsy sampler and syringe |
SU577022A1 (en) | 1976-06-25 | 1977-10-30 | Всесоюзный Научно-Исследовательский Институт Клинической И Экспериментальной Хирургии | Cardiac valve prosthesis |
US4042979A (en) | 1976-07-12 | 1977-08-23 | Angell William W | Valvuloplasty ring and prosthetic method |
DE2703529A1 (en) | 1977-01-28 | 1978-08-03 | Krupp Gmbh | IMPLANT TO CONNECT SEPARATION SITES IN LIVING TISSUE |
US4170990A (en) | 1977-01-28 | 1979-10-16 | Fried. Krupp Gesellschaft Mit Beschrankter Haftung | Method for implanting and subsequently removing mechanical connecting elements from living tissue |
US4103690A (en) | 1977-03-21 | 1978-08-01 | Cordis Corporation | Self-suturing cardiac pacer lead |
US4217902A (en) | 1977-05-02 | 1980-08-19 | March Alfred L | Hemostatic clip |
US4222594A (en) * | 1978-07-10 | 1980-09-16 | Daymond Limited | Swivel couplings |
US4214587A (en) * | 1979-02-12 | 1980-07-29 | Sakura Chester Y Jr | Anastomosis device and method |
US4352358A (en) | 1979-12-28 | 1982-10-05 | Angelchik Jean P | Apparatus for effecting anastomotic procedures |
US4396139A (en) | 1980-02-15 | 1983-08-02 | Technalytics, Inc. | Surgical stapling system, apparatus and staple |
US4345601A (en) | 1980-04-07 | 1982-08-24 | Mamoru Fukuda | Continuous suturing device |
US4324248A (en) | 1980-05-30 | 1982-04-13 | Metatech Corporation | Microsurgical clip |
US4522207A (en) | 1981-02-06 | 1985-06-11 | Charles H. Klieman | Spring activated hemostatic clip applicator |
DD158084A1 (en) | 1981-05-08 | 1982-12-29 | Joachim Heinke | CLOSURE BODY AND METHOD FOR ITS MANUFACTURE |
US4416266A (en) | 1981-05-15 | 1983-11-22 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Medical clip |
US4485816A (en) | 1981-06-25 | 1984-12-04 | Alchemia | Shape-memory surgical staple apparatus and method for use in surgical suturing |
AU8679382A (en) | 1981-08-10 | 1983-02-17 | Ethicon Inc. | Polyolefin surgical device |
US4465071A (en) | 1981-10-26 | 1984-08-14 | Samuels Peter B | Method of applying skin clips |
US4586502A (en) | 1982-02-03 | 1986-05-06 | Ethicon, Inc. | Surgical instrument actuator with non-collinear hydraulic pistons |
US4474181A (en) | 1982-02-18 | 1984-10-02 | Schenck Robert R | Method and apparatus for anastomosing small blood vessels |
US4624255A (en) | 1982-02-18 | 1986-11-25 | Schenck Robert R | Apparatus for anastomosing living vessels |
DE3227984C2 (en) | 1982-07-27 | 1985-10-17 | Abdoll-Hossein Dr. med. 4330 Mülheim Towfigh | Device for producing a tendon butt seam |
US4470533A (en) | 1982-08-13 | 1984-09-11 | Ethicon, Inc. | Surgical instrument for suturing tissues and organs |
US4470415A (en) | 1982-08-19 | 1984-09-11 | The Johns Hopkins University | Sutureless vascular anastomosis means and method |
US4456017A (en) | 1982-11-22 | 1984-06-26 | Cordis Corporation | Coil spring guide with deflectable tip |
SU1186199A1 (en) | 1983-02-15 | 1985-10-23 | Tyumenskij Med I | Method of making anastomoses |
JPS59168848A (en) | 1983-03-11 | 1984-09-22 | エチコン・インコ−ポレ−テツド | Antiseptic surgical apparatus made of nonmetal having affinity to organism |
US4595007A (en) | 1983-03-14 | 1986-06-17 | Ethicon, Inc. | Split ring type tissue fastener |
US4535764A (en) | 1983-04-15 | 1985-08-20 | Tayco Developments, Inc. | Surgical bone tie |
US4573469A (en) | 1983-06-20 | 1986-03-04 | Ethicon, Inc. | Two-piece tissue fastener with coinable leg staple and retaining receiver and method and instrument for applying same |
US4532927A (en) | 1983-06-20 | 1985-08-06 | Ethicon, Inc. | Two-piece tissue fastener with non-reentry bent leg staple and retaining receiver |
US4548202A (en) | 1983-06-20 | 1985-10-22 | Ethicon, Inc. | Mesh tissue fasteners |
EP0140557A3 (en) | 1983-09-12 | 1986-09-03 | Edward Lee Blackwood | Surgical instrument |
DE3335985C2 (en) | 1983-10-04 | 1986-12-04 | Aesculap-Werke Ag Vormals Jetter & Scheerer, 7200 Tuttlingen | Magazine for holding C-shaped scalp clips |
US4665906A (en) | 1983-10-14 | 1987-05-19 | Raychem Corporation | Medical devices incorporating sim alloy elements |
US5190546A (en) | 1983-10-14 | 1993-03-02 | Raychem Corporation | Medical devices incorporating SIM alloy elements |
US4586503A (en) | 1983-12-01 | 1986-05-06 | University Of New Mexico | Surgical microclip |
US4929240A (en) | 1983-12-01 | 1990-05-29 | University Of New Mexico | Surgical clip and applier |
DE3504202A1 (en) | 1984-02-07 | 1985-08-29 | Michael M. Dr. 2000 Wedel Schikorski | Ligation material for ligating tubular organs in human or animal bodies during surgical interventions |
US4549545A (en) | 1984-03-05 | 1985-10-29 | Ethicon Inc. | Segmented polyurethane surgical buttressing pledgets |
US4873975A (en) | 1984-04-10 | 1989-10-17 | Walsh Manufacturing (Mississauga) Limited | Anastomosis device and method |
US6106538A (en) | 1984-05-14 | 2000-08-22 | Shiber; Samuel | Method for forming an internal coronary bypass |
US4932955A (en) | 1984-06-29 | 1990-06-12 | Baxter International Inc. | Clip |
US4706362A (en) | 1984-09-25 | 1987-11-17 | Monarch Marking Systems, Inc. | Method of attaching tags |
US4665917A (en) | 1985-01-28 | 1987-05-19 | Ethicon, Inc. | Tissue gripper for use with intraluminal stapling device |
US4593693A (en) | 1985-04-26 | 1986-06-10 | Schenck Robert R | Methods and apparatus for anastomosing living vessels |
US4683895A (en) | 1985-07-25 | 1987-08-04 | Cordis Corporation | Suture sleeve anchoring device |
US4622970A (en) | 1985-08-29 | 1986-11-18 | The Johns Hopkins University | Vascular everting instrument |
SU1456109A1 (en) | 1986-07-23 | 1989-02-07 | Сибирский физико-технический институт им.В.Д.Кузнецова при Томском государственном университете | Arrangement for bringing together the wound edges |
US5258011A (en) | 1987-01-12 | 1993-11-02 | Drews Robert C | Corneal rivet |
US5119983A (en) | 1987-05-26 | 1992-06-09 | United States Surgical Corporation | Surgical stapler apparatus |
US5171250A (en) | 1987-05-14 | 1992-12-15 | Inbae Yoon | Surgical clips and surgical clip applicator and cutting and transection device |
US5366459A (en) | 1987-05-14 | 1994-11-22 | Inbae Yoon | Surgical clip and clip application procedures |
US4957498A (en) | 1987-11-05 | 1990-09-18 | Concept, Inc. | Suturing instrument |
US4820298A (en) | 1987-11-20 | 1989-04-11 | Leveen Eric G | Internal vascular prosthesis |
US4968315A (en) | 1987-12-15 | 1990-11-06 | Mitek Surgical Products, Inc. | Suture anchor and suture anchor installation tool |
US5084057A (en) | 1989-07-18 | 1992-01-28 | United States Surgical Corporation | Apparatus and method for applying surgical clips in laparoscopic or endoscopic procedures |
JP2561853B2 (en) | 1988-01-28 | 1996-12-11 | 株式会社ジェイ・エム・エス | Shaped memory molded article and method of using the same |
US4926860A (en) | 1988-02-05 | 1990-05-22 | Flexmedics Corporation | ARthroscopic instrumentation and method |
US5002562A (en) * | 1988-06-03 | 1991-03-26 | Oberlander Michael A | Surgical clip |
US5154189A (en) | 1988-06-03 | 1992-10-13 | Oberlander Michael A | Method for repairing a torn meniscus |
SU1560133A1 (en) | 1988-07-11 | 1990-04-30 | Сибирский Физико-Технический Институт При Томском Государственном Университете Им.В.В.Куйбышева | Device for connecting lips of wound |
GB2223410A (en) | 1988-08-31 | 1990-04-11 | Fixit | Surgical device for wound closure and retraction |
US4844318A (en) | 1988-09-06 | 1989-07-04 | Kunreuther Steven J | Needle assembly |
US4990152A (en) * | 1988-10-12 | 1991-02-05 | Inbae Yoon | Applicator device housing multiple elastic ligatures in series and for dilating and applying elastic ligatures onto anatomical tissue |
US5047047A (en) | 1988-10-26 | 1991-09-10 | Inbae Yoon | Wound closing device |
US4924866A (en) | 1988-10-26 | 1990-05-15 | Inbae Yoon | Wound-closing device |
US4994069A (en) * | 1988-11-02 | 1991-02-19 | Target Therapeutics | Vaso-occlusion coil and method |
US4950283A (en) | 1988-12-29 | 1990-08-21 | John Lezdey | Surgical clip |
US4950015A (en) | 1989-01-23 | 1990-08-21 | Design Specialties Laboratories, Inc. | Syringe cap clamp tool |
US5336233A (en) | 1989-01-26 | 1994-08-09 | Chen Fusen H | Anastomotic device |
US4997439A (en) * | 1989-01-26 | 1991-03-05 | Chen Fusen H | Surgical closure or anastomotic device |
WO1990009153A1 (en) | 1989-02-13 | 1990-08-23 | Baxter International Inc. | Selectively flexible annuloplasty ring |
US4930674A (en) | 1989-02-24 | 1990-06-05 | Abiomed, Inc. | Surgical stapler |
US4983176A (en) * | 1989-03-06 | 1991-01-08 | University Of New Mexico | Deformable plastic surgical clip |
US5007920A (en) | 1989-03-24 | 1991-04-16 | Torre Randall J | Tendon sectioning support clamp |
US5020713A (en) | 1989-05-04 | 1991-06-04 | Kunreuther Steven J | Assembly of attachments and device for attaching same |
US5222976A (en) | 1989-05-16 | 1993-06-29 | Inbae Yoon | Suture devices particularly useful in endoscopic surgery |
US5053047A (en) | 1989-05-16 | 1991-10-01 | Inbae Yoon | Suture devices particularly useful in endoscopic surgery and methods of suturing |
US5074874A (en) | 1989-05-16 | 1991-12-24 | Inbae Yoon | Suture devices particularly useful in endoscopic surgery |
US5002550A (en) * | 1989-06-06 | 1991-03-26 | Mitek Surgical Products, Inc. | Suture anchor installation tool |
US5011481A (en) | 1989-07-17 | 1991-04-30 | Medtronic, Inc. | Holder for annuloplasty ring |
US5290300A (en) | 1989-07-31 | 1994-03-01 | Baxter International Inc. | Flexible suture guide and holder |
US5350420A (en) | 1989-07-31 | 1994-09-27 | Baxter International Inc. | Flexible annuloplasty ring and holder |
US5632746A (en) * | 1989-08-16 | 1997-05-27 | Medtronic, Inc. | Device or apparatus for manipulating matter |
US4935027A (en) | 1989-08-21 | 1990-06-19 | Inbae Yoon | Surgical suture instrument with remotely controllable suture material advancement |
US5123913A (en) | 1989-11-27 | 1992-06-23 | Wilk Peter J | Suture device |
US4950285A (en) | 1989-11-27 | 1990-08-21 | Wilk Peter J | Suture device |
US5026379A (en) | 1989-12-05 | 1991-06-25 | Inbae Yoon | Multi-functional instruments and stretchable ligating and occluding devices |
CA2029671A1 (en) | 1989-12-11 | 1991-06-12 | Paul M. Vernon | Grip surgical clip |
US5222961A (en) | 1989-12-26 | 1993-06-29 | Naomi Nakao | Endoscopic stapling device and related staple |
IT1238173B (en) | 1990-01-15 | 1993-07-09 | FOUR-TWO-TWO-TWO-CONVERGENT METAL STITCH SUITABLE FOR CONTEMPORARY SUTURE OF THE SKIN AND SUB-SKIN FABRIC | |
US4991567A (en) * | 1990-01-16 | 1991-02-12 | Mccuen Ii Brooks W | Micro-iris retractor |
US5035692A (en) | 1990-02-13 | 1991-07-30 | Nicholas Herbert | Hemostasis clip applicator |
US5002563A (en) * | 1990-02-22 | 1991-03-26 | Raychem Corporation | Sutures utilizing shape memory alloys |
US5032127A (en) | 1990-03-07 | 1991-07-16 | Frazee John G | Hemostatic clip and applicator therefor |
US5035702A (en) | 1990-06-18 | 1991-07-30 | Taheri Syde A | Method and apparatus for providing an anastomosis |
US5269809A (en) | 1990-07-02 | 1993-12-14 | American Cyanamid Company | Locking mechanism for use with a slotted suture anchor |
US5127413A (en) | 1990-08-09 | 1992-07-07 | Ebert Edward A | Sinous suture |
US5366462A (en) | 1990-08-28 | 1994-11-22 | Robert L. Kaster | Method of side-to-end vascular anastomotic stapling |
US5234447A (en) | 1990-08-28 | 1993-08-10 | Robert L. Kaster | Side-to-end vascular anastomotic staple apparatus |
CA2049103C (en) | 1990-09-06 | 1996-10-01 | Royce Lewis | Implant assist apparatus |
US5353804A (en) | 1990-09-18 | 1994-10-11 | Peb Biopsy Corporation | Method and device for percutaneous exisional breast biopsy |
US5129913A (en) | 1990-10-04 | 1992-07-14 | Norbert Ruppert | Surgical punch apparatus |
US5042707A (en) | 1990-10-16 | 1991-08-27 | Taheri Syde A | Intravascular stapler, and method of operating same |
US5108422A (en) | 1990-10-22 | 1992-04-28 | United States Surgical Corporation | Skin fastener |
FR2668361A1 (en) | 1990-10-30 | 1992-04-30 | Mai Christian | OSTEOSYNTHESIS CLIP AND PLATE WITH SELF-RETENTIVE DYNAMIC COMPRESSION. |
US5519937A (en) * | 1990-11-14 | 1996-05-28 | Soriano; Louis | Guiding method and device for the automatic introduction of a male piece into a female piece |
CA2055985A1 (en) | 1990-12-20 | 1992-06-21 | Daniel Shichman | Fascia clip |
US5221259A (en) | 1990-12-27 | 1993-06-22 | Novoste Corporation | Wound treating device and method of using same |
US5259846A (en) | 1991-01-07 | 1993-11-09 | United States Surgical Corporation | Loop threaded combined surgical needle-suture device |
US5064431A (en) | 1991-01-16 | 1991-11-12 | St. Jude Medical Incorporated | Annuloplasty ring |
US5171252A (en) | 1991-02-05 | 1992-12-15 | Friedland Thomas W | Surgical fastening clip formed of a shape memory alloy, a method of making such a clip and a method of using such a clip |
US5269783A (en) | 1991-05-13 | 1993-12-14 | United States Surgical Corporation | Device and method for repairing torn tissue |
US5217027A (en) | 1991-05-30 | 1993-06-08 | Medtronic, Inc. | Temporary cardiac lead |
GB9111972D0 (en) | 1991-06-04 | 1991-07-24 | Clinical Product Dev Ltd | Medical/surgical devices |
US5452733A (en) | 1993-02-22 | 1995-09-26 | Stanford Surgical Technologies, Inc. | Methods for performing thoracoscopic coronary artery bypass |
US5735290A (en) | 1993-02-22 | 1998-04-07 | Heartport, Inc. | Methods and systems for performing thoracoscopic coronary bypass and other procedures |
US5370685A (en) | 1991-07-16 | 1994-12-06 | Stanford Surgical Technologies, Inc. | Endovascular aortic valve replacement |
US5236435A (en) | 1991-07-22 | 1993-08-17 | Sewell Jr Frank | Laparoscopic surgical staple system |
US5219358A (en) | 1991-08-29 | 1993-06-15 | Ethicon, Inc. | Shape memory effect surgical needles |
DE4133800C1 (en) | 1991-10-12 | 1993-01-21 | Ethicon Gmbh & Co Kg, 2000 Norderstedt, De | |
US5289963A (en) | 1991-10-18 | 1994-03-01 | United States Surgical Corporation | Apparatus and method for applying surgical staples to attach an object to body tissue |
US5152769A (en) | 1991-11-04 | 1992-10-06 | Will Baber | Apparatus for laparoscopic suturing with improved suture needle |
US5242456A (en) | 1991-11-21 | 1993-09-07 | Kensey Nash Corporation | Apparatus and methods for clamping tissue and reflecting the same |
US5163942A (en) * | 1991-12-09 | 1992-11-17 | Everest Medical Corporation | Surgical instrument with grasping loop for laparoscopic procedures |
CA2128338C (en) | 1992-01-21 | 2004-10-12 | Gladwin S. Das | Septal defect closure device |
IL100721A (en) | 1992-01-21 | 1996-12-05 | Milo Simcha | Punch for opening passages between two compartments |
US5201880A (en) | 1992-01-27 | 1993-04-13 | Pioneering Technologies, Inc. | Mitral and tricuspid annuloplasty rings |
US5306296A (en) | 1992-08-21 | 1994-04-26 | Medtronic, Inc. | Annuloplasty and suture rings |
US5628757A (en) | 1992-02-04 | 1997-05-13 | Hasson; Harrith M. | Surgical instrument for holding a needle |
US5261917A (en) | 1992-02-19 | 1993-11-16 | Hasson Harrith M | Suture tying forceps with a plurality of suture holders and method of tying a suture |
US5174087A (en) | 1992-02-19 | 1992-12-29 | Mitek Surgical Products, Inc. | Suture anchor assembly packaging system |
US5178629A (en) | 1992-03-03 | 1993-01-12 | Ethicon, Inc. | Method of forming a suture knot |
DE4303374A1 (en) | 1992-03-12 | 1993-09-23 | Wolf Gmbh Richard | |
US5417700A (en) | 1992-03-30 | 1995-05-23 | Thomas D. Egan | Automatic suturing and ligating device |
US5236440A (en) | 1992-04-14 | 1993-08-17 | American Cyanamid Company | Surgical fastener |
US5355897A (en) | 1992-04-16 | 1994-10-18 | Ethicon, Inc. | Method of performing a pyloroplasty/pylorectomy using a stapler having a shield |
US5242457A (en) | 1992-05-08 | 1993-09-07 | Ethicon, Inc. | Surgical instrument and staples for applying purse string sutures |
US5484451A (en) | 1992-05-08 | 1996-01-16 | Ethicon, Inc. | Endoscopic surgical instrument and staples for applying purse string sutures |
DE4215449C1 (en) | 1992-05-11 | 1993-09-02 | Ethicon Gmbh & Co Kg, 2000 Norderstedt, De | |
US5250053A (en) | 1992-05-29 | 1993-10-05 | Linvatec Corporation | Suture shuttle device |
US5207694A (en) | 1992-06-18 | 1993-05-04 | Surgical Invent Ab | Method for performing a surgical occlusion, and kit and applicator for carrying out the method |
US5653718A (en) | 1994-05-16 | 1997-08-05 | Yoon; Inbae | Cannula anchoring system |
US5334196A (en) | 1992-10-05 | 1994-08-02 | United States Surgical Corporation | Endoscopic fastener remover |
EP0673230A1 (en) | 1992-10-05 | 1995-09-27 | Albert E. Sanders | Nitinol instrumentation and method for treating scoliosis |
CA2133687C (en) | 1992-10-09 | 2007-03-27 | David T. Green | Surgical clip applier |
US5725538A (en) | 1992-10-09 | 1998-03-10 | United States Surgical Corporation | Surgical clip applier |
US5409498A (en) | 1992-11-05 | 1995-04-25 | Ethicon, Inc. | Rotatable articulating endoscopic fastening instrument |
US5304117A (en) | 1992-11-27 | 1994-04-19 | Wilk Peter J | Closure method for use in laparoscopic surgery |
US5403346A (en) | 1992-12-31 | 1995-04-04 | Loeser; Edward A. | Self-affixing suture assembly |
US5632753A (en) | 1992-12-31 | 1997-05-27 | Loeser; Edward A. | Surgical procedures |
US5336239A (en) | 1993-01-15 | 1994-08-09 | Gimpelson Richard J | Surgical needle |
US5366461A (en) | 1993-01-25 | 1994-11-22 | William Blasnik | Sternum banding assembly |
US5356424A (en) | 1993-02-05 | 1994-10-18 | American Cyanamid Co. | Laparoscopic suturing device |
US5304204A (en) | 1993-02-09 | 1994-04-19 | Ethicon, Inc. | Receiverless surgical fasteners |
US5522884A (en) | 1993-02-19 | 1996-06-04 | Medtronic, Inc. | Holder for adjustable mitral & tricuspid annuloplasty rings |
US5569274A (en) | 1993-02-22 | 1996-10-29 | Heartport, Inc. | Endoscopic vascular clamping system and method |
US5799661A (en) | 1993-02-22 | 1998-09-01 | Heartport, Inc. | Devices and methods for port-access multivessel coronary artery bypass surgery |
AU6405994A (en) | 1993-03-11 | 1994-09-26 | Wilson Greatbatch Ltd. | Laparoscopic surgical grasper |
US5312436A (en) | 1993-03-11 | 1994-05-17 | Coffey William R | Suture for use in endoscopic surgery |
US5403331A (en) | 1993-03-12 | 1995-04-04 | United States Surgical Corporation | Looped suture ligating device containing a heat-shrinkable element |
US5346459A (en) | 1993-04-14 | 1994-09-13 | Minnesota Mining And Manufacturing Company | Trocar |
JP3180219B2 (en) | 1993-07-09 | 2001-06-25 | ニプロ株式会社 | Trocar |
US5462561A (en) | 1993-08-05 | 1995-10-31 | Voda; Jan K. | Suture device |
AU7568994A (en) * | 1993-08-25 | 1995-03-21 | Apollo Camera, L.L.C. | Surgical ligation clip |
US5450860A (en) | 1993-08-31 | 1995-09-19 | W. L. Gore & Associates, Inc. | Device for tissue repair and method for employing same |
FR2710254B1 (en) | 1993-09-21 | 1995-10-27 | Mai Christian | Multi-branch osteosynthesis clip with self-retaining dynamic compression. |
CA2132917C (en) | 1993-10-07 | 2004-12-14 | John Charles Robertson | Circular anastomosis device |
US5569301A (en) | 1993-10-08 | 1996-10-29 | United States Surgical Corporation | Surgical incision members for endoscopic suturing apparatus |
US5632752A (en) | 1993-10-12 | 1997-05-27 | Urohealth Systems, Inc. | Surgical suturing device |
WO1995011630A1 (en) | 1993-10-25 | 1995-05-04 | Children's Medical Center Corporation | Retractable suture needle with self-contained driver |
US5503635A (en) | 1993-11-12 | 1996-04-02 | United States Surgical Corporation | Apparatus and method for performing compressional anastomoses |
WO1995016407A1 (en) | 1993-12-13 | 1995-06-22 | Brigham And Women's Hospital | Aortic valve supporting device |
US5527342A (en) | 1993-12-14 | 1996-06-18 | Pietrzak; William S. | Method and apparatus for securing soft tissues, tendons and ligaments to bone |
US5376096A (en) | 1993-12-17 | 1994-12-27 | Vance Products Inc. | Medical instrument for driving a suture needle |
DK145593A (en) | 1993-12-23 | 1995-06-24 | Joergen A Rygaard | Surgical double instrument for performing connection mlm. arteries (end-to-side anastomosis) |
US5782397A (en) | 1994-01-04 | 1998-07-21 | Alpha Surgical Technologies, Inc. | Stapling device |
US5437681A (en) | 1994-01-13 | 1995-08-01 | Suturtek Inc. | Suturing instrument with thread management |
US5423821A (en) | 1994-01-18 | 1995-06-13 | Pasque; Michael K. | Sternal closure device |
DE4402058C1 (en) | 1994-01-25 | 1995-04-13 | Andreas Dr Med Asch | Implantable temporary electrode cable |
US5538509A (en) | 1994-01-31 | 1996-07-23 | Richard-Allan Medical Industries, Inc. | Trocar assembly |
US5456246A (en) | 1994-02-23 | 1995-10-10 | Arthrex, Inc. | Fat pad retractor |
US5431666A (en) | 1994-02-24 | 1995-07-11 | Lasersurge, Inc. | Surgical suture instrument |
US5451231A (en) | 1994-03-11 | 1995-09-19 | Ryder International Corporation | Surgical staple remover |
JP3526609B2 (en) * | 1994-03-31 | 2004-05-17 | テルモ株式会社 | Suture instrument |
US5601571A (en) * | 1994-05-17 | 1997-02-11 | Moss; Gerald | Surgical fastener implantation device |
EP0765137B1 (en) | 1994-06-17 | 2003-07-30 | Heartport, Inc. | Surgical stapling instrument |
US5569205A (en) | 1994-07-14 | 1996-10-29 | Hart; Charles C. | Multiport trocar |
US5582616A (en) | 1994-08-05 | 1996-12-10 | Origin Medsystems, Inc. | Surgical helical fastener with applicator |
US5562685A (en) | 1994-09-16 | 1996-10-08 | General Surgical Innovations, Inc. | Surgical instrument for placing suture or fasteners |
CA2157744C (en) | 1994-10-07 | 2005-08-23 | Charles R. Sherts | Endoscopic vascular suturing apparatus |
US5571090A (en) | 1994-10-07 | 1996-11-05 | United States Surgical Corporation | Vascular suturing apparatus |
CA2162620A1 (en) | 1994-11-11 | 1996-05-12 | Gene Samson | Microcatheter-less coil delivery device |
US5643305A (en) | 1994-11-18 | 1997-07-01 | Al-Tameem; Moshin | Device for excision of a fistula |
US5653716A (en) | 1994-12-29 | 1997-08-05 | Acufex Microsurgical, Inc. | Suture manipulating instrument with grasping members |
US5643295A (en) | 1994-12-29 | 1997-07-01 | Yoon; Inbae | Methods and apparatus for suturing tissue |
US5665109A (en) | 1994-12-29 | 1997-09-09 | Yoon; Inbae | Methods and apparatus for suturing tissue |
US5797933A (en) | 1996-07-16 | 1998-08-25 | Heartport, Inc. | Coronary shunt and method of use |
US5976159A (en) | 1995-02-24 | 1999-11-02 | Heartport, Inc. | Surgical clips and methods for tissue approximation |
US5695504A (en) | 1995-02-24 | 1997-12-09 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US5795308A (en) | 1995-03-09 | 1998-08-18 | Russin; Lincoln D. | Apparatus for coaxial breast biopsy |
DE19509115C2 (en) | 1995-03-16 | 1997-11-27 | Deutsche Forsch Luft Raumfahrt | Surgical device for preparing an anastomosis using minimally invasive surgical techniques |
CA2173023C (en) | 1995-03-30 | 2001-08-28 | David Kupiecki | Liquid coils with secondary shape |
US5591179A (en) * | 1995-04-19 | 1997-01-07 | Applied Medical Resources Corporation | Anastomosis suturing device and method |
US5609608A (en) | 1995-10-27 | 1997-03-11 | Regents Of The University Of California | Miniature plastic gripper and fabrication method |
US5630540A (en) | 1995-05-24 | 1997-05-20 | United States Surgical Corporation | Surgical staple and staple drive member |
US5660186A (en) | 1995-06-07 | 1997-08-26 | Marshfield Clinic | Spiral biopsy stylet |
US6132438A (en) | 1995-06-07 | 2000-10-17 | Ep Technologies, Inc. | Devices for installing stasis reducing means in body tissue |
US5571175A (en) | 1995-06-07 | 1996-11-05 | St. Jude Medical, Inc. | Suture guard for prosthetic heart valve |
WO1997001368A1 (en) | 1995-06-26 | 1997-01-16 | Trimedyne, Inc. | Therapeutic appliance releasing device |
US5582619A (en) | 1995-06-30 | 1996-12-10 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils |
US5533236A (en) | 1995-08-08 | 1996-07-09 | Chun-Hsiung Hsu | Paper holder |
US5601600A (en) * | 1995-09-08 | 1997-02-11 | Conceptus, Inc. | Endoluminal coil delivery system having a mechanical release mechanism |
CA2184958A1 (en) | 1995-09-22 | 1997-03-23 | John S. Gentelia | Improved trocar-cannulla device |
US5702412A (en) | 1995-10-03 | 1997-12-30 | Cedars-Sinai Medical Center | Method and devices for performing vascular anastomosis |
US5690662A (en) | 1995-10-12 | 1997-11-25 | The Trustees Of Columbia University In The City Of New York | Device and method to create a smooth opening on a tubular structure such as an artery or a vein |
IL124037A (en) | 1995-10-13 | 2003-01-12 | Transvascular Inc | Device and system for interstitial transvascular intervention |
US5700271A (en) | 1995-10-20 | 1997-12-23 | United States Surgical Corporation | Apparatus for applying surgical clips |
US5700270A (en) | 1995-10-20 | 1997-12-23 | United States Surgical Corporation | Surgical clip applier |
US5941442A (en) | 1995-10-27 | 1999-08-24 | United States Surgical | Surgical stapler |
ATE188862T1 (en) | 1995-10-31 | 2000-02-15 | Oticon As | ANASTOMOTIC INSTRUMENT FOR USE IN A TERMINOLATERAL ANASTOMOSIS |
BE1009746A3 (en) | 1995-11-07 | 1997-07-01 | Dereume Jean Pierre Georges Em | Capture device introduced in a cavity of a human or animal body. |
US5645568A (en) | 1995-11-20 | 1997-07-08 | Medicinelodge, Inc. | Expandable body suture |
US5658308A (en) | 1995-12-04 | 1997-08-19 | Target Therapeutics, Inc. | Bioactive occlusion coil |
DE19547617C1 (en) | 1995-12-20 | 1997-09-18 | Malte Neus | Appliance for inserting and replacing surgical implant |
US5810853A (en) | 1996-01-16 | 1998-09-22 | Yoon; Inbae | Knotting element for use in suturing anatomical tissue and methods therefor |
RU2110222C1 (en) | 1996-01-18 | 1998-05-10 | Устинова Елена Юрьевна | Device for forming of intestinal end-to-end anastomosis |
US5827265A (en) | 1996-02-07 | 1998-10-27 | Regents Of The University Of California | Intraluminal tissue welding for anastomosis |
US5769870A (en) | 1996-02-20 | 1998-06-23 | Cardiothoracic Systems, Inc. | Perfusion device for maintaining blood flow in a vessel while isolating an anastomosis |
US5891160A (en) | 1996-02-23 | 1999-04-06 | Cardiovascular Technologies, Llc | Fastener delivery and deployment mechanism and method for placing the fastener in minimally invasive surgery |
JP3776529B2 (en) | 1996-02-29 | 2006-05-17 | オリンパス株式会社 | Clip device |
EP0889704A1 (en) | 1996-02-29 | 1999-01-13 | Oticon A/S | Method and anastomotic instrument for use when performing an end-to-side anastomosis |
US5810851A (en) | 1996-03-05 | 1998-09-22 | Yoon; Inbae | Suture spring device |
US5782844A (en) | 1996-03-05 | 1998-07-21 | Inbae Yoon | Suture spring device applicator |
EP0904019B1 (en) | 1996-04-30 | 2002-05-22 | Oticon A/S | Anastomotic instrument for use when performing an end-to-side anastomosis |
US5746753A (en) | 1996-05-13 | 1998-05-05 | Boston Scientific Corporation | Needle grasping apparatus |
US5800421A (en) | 1996-06-12 | 1998-09-01 | Lemelson; Jerome H. | Medical devices using electrosensitive gels |
US5676670A (en) | 1996-06-14 | 1997-10-14 | Beth Israel Deaconess Medical Center | Catheter apparatus and method for creating a vascular bypass in-vivo |
US5797920A (en) | 1996-06-14 | 1998-08-25 | Beth Israel Deaconess Medical Center | Catheter apparatus and method using a shape-memory alloy cuff for creating a bypass graft in-vivo |
US6007544A (en) | 1996-06-14 | 1999-12-28 | Beth Israel Deaconess Medical Center | Catheter apparatus having an improved shape-memory alloy cuff and inflatable on-demand balloon for creating a bypass graft in-vivo |
JP3304346B2 (en) | 1996-06-20 | 2002-07-22 | ニプロ株式会社 | Suture for endocardial suture surgery |
US5833698A (en) | 1996-07-23 | 1998-11-10 | United States Surgical Corporation | Anastomosis instrument and method |
US5820631A (en) | 1996-08-01 | 1998-10-13 | Nr Medical, Inc. | Device and method for suturing tissue adjacent to a blood vessel |
FR2751867B1 (en) | 1996-08-05 | 1999-05-21 | Leriche Rene Ass | PROSTHESIS COLLERETTE |
US5697913A (en) | 1996-08-09 | 1997-12-16 | Ethicon Endo-Surgery, Inc. | Trocar including cannula with stepped region |
US5683417A (en) | 1996-08-14 | 1997-11-04 | Cooper; William I. | Suture and method for endoscopic surgery |
US5810848A (en) | 1996-08-21 | 1998-09-22 | Hayhurst; John O. | Suturing system |
US5871495A (en) | 1996-09-13 | 1999-02-16 | Eclipse Surgical Technologies, Inc. | Method and apparatus for mechanical transmyocardial revascularization of the heart |
US5976164A (en) | 1996-09-13 | 1999-11-02 | Eclipse Surgical Technologies, Inc. | Method and apparatus for myocardial revascularization and/or biopsy of the heart |
US5830221A (en) | 1996-09-20 | 1998-11-03 | United States Surgical Corporation | Coil fastener applier |
DE29616632U1 (en) | 1996-09-24 | 1996-11-28 | Aesculap Ag | Surgical application device for U-shaped clips |
US5762646A (en) * | 1996-09-30 | 1998-06-09 | Duxbury Scientific, Inc. | Blood collection system and coupling |
US5941434A (en) | 1996-10-11 | 1999-08-24 | Green; Mark R. | Multi-strap holder |
US5755778A (en) | 1996-10-16 | 1998-05-26 | Nitinol Medical Technologies, Inc. | Anastomosis device |
US5941908A (en) | 1997-04-23 | 1999-08-24 | Vascular Science, Inc. | Artificial medical graft with a releasable retainer |
US5976178A (en) | 1996-11-07 | 1999-11-02 | Vascular Science Inc. | Medical grafting methods |
EP1011458A2 (en) | 1996-11-08 | 2000-06-28 | Russell A. Houser | Percutaneous bypass graft and securing system |
CA2224366C (en) | 1996-12-11 | 2006-10-31 | Ethicon, Inc. | Meniscal repair device |
US5911352A (en) | 1996-12-17 | 1999-06-15 | United States Surgical Corporation | Surgical stapling apparatus |
US5972024A (en) | 1996-12-24 | 1999-10-26 | Metacardia, Inc. | Suture-staple apparatus and method |
US6074401A (en) | 1997-01-09 | 2000-06-13 | Coalescent Surgical, Inc. | Pinned retainer surgical fasteners, instruments and methods for minimally invasive vascular and endoscopic surgery |
US6149658A (en) | 1997-01-09 | 2000-11-21 | Coalescent Surgical, Inc. | Sutured staple surgical fasteners, instruments and methods for minimally invasive vascular and endoscopic surgery |
US5961539A (en) | 1997-01-17 | 1999-10-05 | Segmed, Inc. | Method and apparatus for sizing, stabilizing and/or reducing the circumference of an anatomical structure |
US5957938A (en) | 1997-02-05 | 1999-09-28 | United States Surgical Corporation | Tissue everting needle |
US5893369A (en) | 1997-02-24 | 1999-04-13 | Lemole; Gerald M. | Procedure for bypassing an occlusion in a blood vessel |
US5944730A (en) | 1997-05-19 | 1999-08-31 | Cardio Medical Solutions, Inc. | Device and method for assisting end-to-side anastomosis |
US6409739B1 (en) | 1997-05-19 | 2002-06-25 | Cardio Medical Solutions, Inc. | Device and method for assisting end-to side anastomosis |
US5908428A (en) | 1997-05-27 | 1999-06-01 | United States Surgical Corporation | Stitching devices for heart valve replacement surgery |
US5827316A (en) | 1997-06-05 | 1998-10-27 | Atrion Medical Products, Inc. | Rotating aortic punch |
EP0930845B1 (en) | 1997-06-27 | 2009-10-14 | The Trustees Of Columbia University In The City Of New York | Apparatus for circulatory valve repair |
US6071292A (en) | 1997-06-28 | 2000-06-06 | Transvascular, Inc. | Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures |
US5997556A (en) | 1997-06-30 | 1999-12-07 | Eva Corporation | Surgical fastener |
US5957940A (en) | 1997-06-30 | 1999-09-28 | Eva Corporation | Fasteners for use in the surgical repair of aneurysms |
DE19732234A1 (en) | 1997-07-26 | 1999-01-28 | Georg Dr Med Quatchadze | Surgical endoscopic instrument |
US6063070A (en) | 1997-08-05 | 2000-05-16 | Target Therapeutics, Inc. | Detachable aneurysm neck bridge (II) |
US5964782A (en) | 1997-09-18 | 1999-10-12 | Scimed Life Systems, Inc. | Closure device and method |
US5984959A (en) | 1997-09-19 | 1999-11-16 | United States Surgical | Heart valve replacement tools and procedures |
US5893865A (en) | 1997-09-23 | 1999-04-13 | Baxter Research Medical, Inc. | Apparatus and method for improved aortic incision |
US6074416A (en) | 1997-10-09 | 2000-06-13 | St. Jude Medical Cardiovascular Group, Inc. | Wire connector structures for tubular grafts |
NL1007349C2 (en) | 1997-10-24 | 1999-04-27 | Suyker Wilhelmus Joseph Leonardus | System for the mechanical production of anastomoses between hollow structures; as well as device and applicator for use therewith. |
US5989268A (en) | 1997-10-28 | 1999-11-23 | Boston Scientific Corporation | Endoscopic hemostatic clipping device |
US6139540A (en) | 1997-10-30 | 2000-10-31 | Lake Region Manufacturing, Inc. | Guidewire with disposition to coil |
US6159165A (en) | 1997-12-05 | 2000-12-12 | Micrus Corporation | Three dimensional spherical micro-coils manufactured from radiopaque nickel-titanium microstrand |
US6241691B1 (en) | 1997-12-05 | 2001-06-05 | Micrus Corporation | Coated superelastic stent |
US6332893B1 (en) | 1997-12-17 | 2001-12-25 | Myocor, Inc. | Valve to myocardium tension members device and method |
US5976161A (en) | 1998-01-07 | 1999-11-02 | University Of New Mexico | Tissue everting apparatus and method |
US5919199A (en) | 1998-01-14 | 1999-07-06 | Mers Kelly; William Charles | Suture device |
IT1304761B1 (en) | 1998-01-20 | 2001-03-29 | Nardino Righi | DISPOSABLE SAFETY SYRINGE. |
US6416527B1 (en) | 1998-01-28 | 2002-07-09 | St. Jude Medical Cardiovascular Group, Inc. | Vessel cutting device |
JP4187411B2 (en) | 1998-01-30 | 2008-11-26 | セント ジュード メディカル エーティージー, インコーポレイテッド | Device for use in closing a septal defect |
US6651670B2 (en) | 1998-02-13 | 2003-11-25 | Ventrica, Inc. | Delivering a conduit into a heart wall to place a coronary vessel in communication with a heart chamber and removing tissue from the vessel or heart wall to facilitate such communication |
US6352543B1 (en) | 2000-04-29 | 2002-03-05 | Ventrica, Inc. | Methods for forming anastomoses using magnetic force |
US6280460B1 (en) | 1998-02-13 | 2001-08-28 | Heartport, Inc. | Devices and methods for performing vascular anastomosis |
US5941888A (en) | 1998-02-18 | 1999-08-24 | Target Therapeutics, Inc. | Vaso-occlusive member assembly with multiple detaching points |
US5951576A (en) | 1998-03-02 | 1999-09-14 | Wakabayashi; Akio | End-to-side vascular anastomosing stapling device |
US6110188A (en) | 1998-03-09 | 2000-08-29 | Corvascular, Inc. | Anastomosis method |
US6241741B1 (en) | 1998-03-09 | 2001-06-05 | Corvascular Surgical Systems, Inc. | Anastomosis device and method |
NO981277D0 (en) | 1998-03-20 | 1998-03-20 | Erik Fosse | Method and apparatus for suture-free anastomosis |
US6056751A (en) | 1998-04-16 | 2000-05-02 | Axya Medical, Inc. | Sutureless soft tissue fixation assembly |
US6074418A (en) | 1998-04-20 | 2000-06-13 | St. Jude Medical, Inc. | Driver tool for heart valve prosthesis fasteners |
US6113611A (en) | 1998-05-28 | 2000-09-05 | Advanced Vascular Technologies, Llc | Surgical fastener and delivery system |
US7063711B1 (en) | 1998-05-29 | 2006-06-20 | By-Pass, Inc. | Vascular surgery |
KR20010052459A (en) | 1998-05-29 | 2001-06-25 | 바이-패스, 인크. | Methods and devices for vascular surgery |
US6979338B1 (en) | 1998-05-29 | 2005-12-27 | By-Pass Inc. | Low profile anastomosis connector |
US5919207A (en) | 1998-06-02 | 1999-07-06 | Taheri; Syde A. | Percutaneous arterial closure with staples |
US6641593B1 (en) | 1998-06-03 | 2003-11-04 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
EP1005294A1 (en) | 1998-06-10 | 2000-06-07 | Advanced Bypass Technologies, Inc. | Sutureless anastomosis systems |
US6250308B1 (en) | 1998-06-16 | 2001-06-26 | Cardiac Concepts, Inc. | Mitral valve annuloplasty ring and method of implanting |
US6165183A (en) | 1998-07-15 | 2000-12-26 | St. Jude Medical, Inc. | Mitral and tricuspid valve repair |
US6418597B1 (en) | 1998-07-15 | 2002-07-16 | Avery Dennison Corporation | Plastic fastener, fastener clip, fastener dispensing tool and method of fastening objects |
US6461320B1 (en) | 1998-08-12 | 2002-10-08 | Cardica, Inc. | Method and system for attaching a graft to a blood vessel |
US6206913B1 (en) | 1998-08-12 | 2001-03-27 | Vascular Innovations, Inc. | Method and system for attaching a graft to a blood vessel |
US6143004A (en) | 1998-08-18 | 2000-11-07 | Atrion Medical Products, Inc. | Suturing device |
US6296622B1 (en) | 1998-12-21 | 2001-10-02 | Micrus Corporation | Endoluminal device delivery system using axially recovering shape memory material |
US6083237A (en) | 1998-10-23 | 2000-07-04 | Ethico Endo-Surgery, Inc. | Biopsy instrument with tissue penetrating spiral |
US6475222B1 (en) | 1998-11-06 | 2002-11-05 | St. Jude Medical Atg, Inc. | Minimally invasive revascularization apparatus and methods |
US6152937A (en) | 1998-11-06 | 2000-11-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical graft connector and methods of making and installing same |
US6113612A (en) | 1998-11-06 | 2000-09-05 | St. Jude Medical Cardiovascular Group, Inc. | Medical anastomosis apparatus |
US6221083B1 (en) | 1998-11-16 | 2001-04-24 | Paul W. Mayer | Synchronized stapler/needle driver/forceps for motion in all planes |
GB9827415D0 (en) | 1998-12-11 | 1999-02-03 | Wild Andrew M | Surgical apparatus and method for occluding a body passageway |
US6120524A (en) | 1999-02-16 | 2000-09-19 | Taheri; Syde A. | Device for closing an arterial puncture and method |
US8118822B2 (en) | 1999-03-01 | 2012-02-21 | Medtronic, Inc. | Bridge clip tissue connector apparatus and methods |
US6406492B1 (en) | 1999-04-08 | 2002-06-18 | Sulzer Carbomedics Inc. | Annuloplasty ring holder |
US6248117B1 (en) | 1999-04-16 | 2001-06-19 | Vital Access Corp | Anastomosis apparatus for use in intraluminally directed vascular anastomosis |
US6623494B1 (en) | 1999-04-16 | 2003-09-23 | Integrated Vascular Interventional Technologies, L.C. (Ivit, Lc) | Methods and systems for intraluminally directed vascular anastomosis |
US6743244B2 (en) | 1999-04-16 | 2004-06-01 | Integrated Vascular Interventional Technologies, L.C. | Soft anvil apparatus for cutting anastomosis fenestra |
AU5143000A (en) | 1999-05-18 | 2000-12-05 | Vascular Innovations, Inc. | Implantable medical device such as an anastomosis device |
US6428550B1 (en) | 1999-05-18 | 2002-08-06 | Cardica, Inc. | Sutureless closure and deployment system for connecting blood vessels |
US6217611B1 (en) | 1999-05-26 | 2001-04-17 | Sulzer Carbomedics Inc. | Modular heart valve prothesis |
US6699256B1 (en) | 1999-06-04 | 2004-03-02 | St. Jude Medical Atg, Inc. | Medical grafting apparatus and methods |
US7192442B2 (en) | 1999-06-30 | 2007-03-20 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
US6165185A (en) | 1999-07-28 | 2000-12-26 | Vasconnect, Inc. | Method for interconnecting vessels in a patient |
US6391038B2 (en) | 1999-07-28 | 2002-05-21 | Cardica, Inc. | Anastomosis system and method for controlling a tissue site |
US6635214B2 (en) | 1999-09-10 | 2003-10-21 | Ventrica, Inc. | Manufacturing conduits for use in placing a target vessel in fluid communication with a source of blood |
CA2381818C (en) | 1999-09-13 | 2009-08-04 | Rex Medical, L.P. | Vascular closure |
US6358258B1 (en) | 1999-09-14 | 2002-03-19 | Abbott Laboratories | Device and method for performing end-to-side anastomosis |
US6926730B1 (en) | 2000-10-10 | 2005-08-09 | Medtronic, Inc. | Minimally invasive valve repair procedure and apparatus |
US6402764B1 (en) | 1999-11-15 | 2002-06-11 | Cardica, Inc. | Everter and threadthrough system for attaching graft vessel to anastomosis device |
US6428555B1 (en) | 2000-01-28 | 2002-08-06 | J. Kenneth Koster, Jr. | Anastomosis punch device and method |
US6797002B2 (en) | 2000-02-02 | 2004-09-28 | Paul A. Spence | Heart valve repair apparatus and methods |
US6551332B1 (en) | 2000-03-31 | 2003-04-22 | Coalescent Surgical, Inc. | Multiple bias surgical fastener |
US6802847B1 (en) | 2000-04-29 | 2004-10-12 | Ventrica, Inc. | Devices and methods for forming magnetic anastomoses and ports in vessels |
US6368348B1 (en) | 2000-05-15 | 2002-04-09 | Shlomo Gabbay | Annuloplasty prosthesis for supporting an annulus of a heart valve |
US6869444B2 (en) | 2000-05-22 | 2005-03-22 | Shlomo Gabbay | Low invasive implantable cardiac prosthesis and method for helping improve operation of a heart valve |
US6419695B1 (en) | 2000-05-22 | 2002-07-16 | Shlomo Gabbay | Cardiac prosthesis for helping improve operation of a heart valve |
US6406493B1 (en) | 2000-06-02 | 2002-06-18 | Hosheng Tu | Expandable annuloplasty ring and methods of use |
EP1330189B1 (en) | 2000-06-23 | 2007-12-19 | Viacor Incorporated | Automated annular plication for mitral valve repair |
US6409758B2 (en) | 2000-07-27 | 2002-06-25 | Edwards Lifesciences Corporation | Heart valve holder for constricting the valve commissures and methods of use |
EP1331889A1 (en) | 2000-09-01 | 2003-08-06 | Advanced Vascular Technologies LLC | Vascular bypass grafting instrument and method |
US6918917B1 (en) | 2000-10-10 | 2005-07-19 | Medtronic, Inc. | Minimally invasive annuloplasty procedure and apparatus |
US6776785B1 (en) | 2000-10-12 | 2004-08-17 | Cardica, Inc. | Implantable superelastic anastomosis device |
US6425900B1 (en) | 2000-10-19 | 2002-07-30 | Ethicon Endo-Surgery | Method for attaching hernia mesh |
US7070618B2 (en) | 2000-10-25 | 2006-07-04 | Viacor, Inc. | Mitral shield |
EP1210912A3 (en) * | 2000-11-27 | 2003-12-17 | Terumo Kabushiki Kaisha | Instrument for extroverting blood vessel |
US6537286B2 (en) | 2001-01-19 | 2003-03-25 | Sergio Acampora | Device for fastening a cranial flap to the cranial vault |
JP4097924B2 (en) | 2001-02-05 | 2008-06-11 | オリンパス株式会社 | Biological tissue clip device |
US20020173803A1 (en) | 2001-05-01 | 2002-11-21 | Stephen Ainsworth | Self-closing surgical clip for tissue |
US20060293701A1 (en) | 2001-05-02 | 2006-12-28 | Medtronic, Inc. | Self-closing surgical clip for tissue |
US6562053B2 (en) | 2001-05-21 | 2003-05-13 | Ethicon, Inc. | Curved mandrel for assisting vessel eversion |
US6547799B2 (en) | 2001-06-26 | 2003-04-15 | Ethicon, Inc. | Vessel eversion instrument with pressurizable membrane |
US6776782B2 (en) | 2001-06-26 | 2004-08-17 | Ethicon, Inc. | Vessel eversion instrument with wiping element |
US6589255B2 (en) | 2001-06-28 | 2003-07-08 | Ethicon, Inc. | Vessel eversion instrument with filament elements |
US6629988B2 (en) | 2001-08-28 | 2003-10-07 | Ethicon, Inc. | Composite staple for completing an anastomosis |
US6776784B2 (en) | 2001-09-06 | 2004-08-17 | Core Medical, Inc. | Clip apparatus for closing septal defects and methods of use |
US6712829B2 (en) | 2001-09-10 | 2004-03-30 | Ethicon, Inc. | Vessel eversion instrument with conical, expandable mandrel |
US6575985B2 (en) | 2001-09-10 | 2003-06-10 | Ethicon, Inc. | Vessel eversion instrument with conical holder |
US6821286B1 (en) | 2002-01-23 | 2004-11-23 | Cardica, Inc. | System for preparing a graft vessel for anastomosis |
US20030199974A1 (en) | 2002-04-18 | 2003-10-23 | Coalescent Surgical, Inc. | Annuloplasty apparatus and methods |
US7056330B2 (en) | 2002-05-31 | 2006-06-06 | Ethicon Endo-Surgery, Inc. | Method for applying tissue fastener |
US8066724B2 (en) | 2002-09-12 | 2011-11-29 | Medtronic, Inc. | Anastomosis apparatus and methods |
US8105345B2 (en) | 2002-10-04 | 2012-01-31 | Medtronic, Inc. | Anastomosis apparatus and methods |
US7399310B2 (en) | 2002-12-16 | 2008-07-15 | Edrich Vascular Devices, Inc. | Endovascular stapler |
US8377082B2 (en) | 2003-01-14 | 2013-02-19 | Medtronic, Inc. | Methods and apparatus for making precise incisions in body vessels |
US20040193259A1 (en) | 2003-03-25 | 2004-09-30 | Shlomo Gabbay | Sizing apparatus for cardiac prostheses and method of using same |
US20050107871A1 (en) | 2003-03-30 | 2005-05-19 | Fidel Realyvasquez | Apparatus and methods for valve repair |
US20060271081A1 (en) | 2003-03-30 | 2006-11-30 | Fidel Realyvasquez | Apparatus and methods for valve repair |
US20050075659A1 (en) | 2003-03-30 | 2005-04-07 | Fidel Realyvasquez | Apparatus and methods for minimally invasive valve surgery |
US8394114B2 (en) | 2003-09-26 | 2013-03-12 | Medtronic, Inc. | Surgical connection apparatus and methods |
US7556647B2 (en) | 2003-10-08 | 2009-07-07 | Arbor Surgical Technologies, Inc. | Attachment device and methods of using the same |
US7879047B2 (en) | 2003-12-10 | 2011-02-01 | Medtronic, Inc. | Surgical connection apparatus and methods |
JP2007537794A (en) | 2004-05-14 | 2007-12-27 | セント ジュード メディカル インコーポレイテッド | System and method for holding an annuloplasty ring |
-
2003
- 2003-08-22 US US10/646,254 patent/US20050043749A1/en not_active Abandoned
-
2006
- 2006-09-14 US US11/521,152 patent/US8029519B2/en not_active Expired - Fee Related
-
2008
- 2008-09-22 US US12/235,445 patent/US20090240265A1/en not_active Abandoned
Patent Citations (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US424518A (en) * | 1890-04-01 | Needle-threader | ||
US1087186A (en) * | 1909-03-22 | 1914-02-17 | Socrates Scholfield | Illustrative educational device. |
US1167014A (en) * | 1915-06-25 | 1916-01-04 | William R O'brien | Veterinary surgical instrument. |
US2042403A (en) * | 1935-02-27 | 1936-05-26 | Hrivnak Andrew | Needle threader |
US3082426A (en) * | 1960-06-17 | 1963-03-26 | George Oliver Halsted | Surgical stapling device |
US3404707A (en) * | 1966-06-29 | 1968-10-08 | Henry Heckmann | Thread pulling needle devices |
US3570497A (en) * | 1969-01-16 | 1971-03-16 | Gerald M Lemole | Suture apparatus and methods |
US3638654A (en) * | 1969-07-11 | 1972-02-01 | Uche Akuba | Suturing instrument |
US4006747A (en) * | 1975-04-23 | 1977-02-08 | Ethicon, Inc. | Surgical method |
US4140125A (en) * | 1976-02-25 | 1979-02-20 | Med-Pro, Ltd. | Surgical tape device |
US4073179A (en) * | 1976-06-01 | 1978-02-14 | Codman & Shurtleff, Inc. | Clip removing device |
US4243048A (en) * | 1976-09-21 | 1981-01-06 | Jim Zegeer | Biopsy device |
US4192315A (en) * | 1976-12-23 | 1980-03-11 | Aesculap-Werke Aktiengesellschaft Vormals Jetter & Scheerer | Clip for surgical purposes |
US4102478A (en) * | 1976-12-27 | 1978-07-25 | Constantin Samoilov | Needle threader |
US4185636A (en) * | 1977-12-29 | 1980-01-29 | Albert Einstein College Of Medicine Of Yeshiva University | Suture organizer, prosthetic device holder, and related surgical procedures |
US4366819A (en) * | 1980-11-17 | 1983-01-04 | Kaster Robert L | Anastomotic fitting |
US4809695A (en) * | 1981-10-21 | 1989-03-07 | Owen M. Gwathmey | Suturing assembly and method |
US4492229A (en) * | 1982-09-03 | 1985-01-08 | Grunwald Ronald P | Suture guide holder |
US4523592A (en) * | 1983-04-25 | 1985-06-18 | Rollin K. Daniel P.S.C. | Anastomotic coupling means capable of end-to-end and end-to-side anastomosis |
US4641652A (en) * | 1984-04-12 | 1987-02-10 | Richard Wolf Gmbh | Applicator for tying sewing threads |
US4576605A (en) * | 1985-03-01 | 1986-03-18 | Nauchno-Issledovatelsky Institut Khirurgii Imeni A.V. Vishnevskogo | Cardiac valve prosthesis |
US4637380A (en) * | 1985-06-24 | 1987-01-20 | Orejola Wilmo C | Surgical wound closures |
US4779616A (en) * | 1986-02-04 | 1988-10-25 | Johnson Lanny L | Surgical suture-snagging method |
US4730615A (en) * | 1986-03-03 | 1988-03-15 | Pfizer Hospital Products Group, Inc. | Sternum closure device |
US4896668A (en) * | 1986-04-10 | 1990-01-30 | Peters | Plate set for osteal fixation, equipped with suture strands |
US4719924A (en) * | 1986-09-09 | 1988-01-19 | C. R. Bard, Inc. | Small diameter steerable guidewire with adjustable tip |
US4732151A (en) * | 1986-10-08 | 1988-03-22 | Patent Research & Development Corp. | Low trauma suturing |
US4719917A (en) * | 1987-02-17 | 1988-01-19 | Minnesota Mining And Manufacturing Company | Surgical staple |
US5100418A (en) * | 1987-05-14 | 1992-03-31 | Inbae Yoon | Suture tie device system and applicator therefor |
US5480405A (en) * | 1987-05-14 | 1996-01-02 | Yoon; Inbae | Anchor applier instrument for use in suturing tissue |
US4890615A (en) * | 1987-11-05 | 1990-01-02 | Concept, Inc. | Arthroscopic suturing instrument |
US4890615B1 (en) * | 1987-11-05 | 1993-11-16 | Linvatec Corporation | Arthroscopic suturing instrument |
US4901721A (en) * | 1988-08-02 | 1990-02-20 | Hakki Samir I | Suturing device |
US5196022A (en) * | 1988-12-12 | 1993-03-23 | Ethicon, Inc. | Ligature system for use in endoscopic surgery, ligature and handling instrument for said system |
US4899744A (en) * | 1988-12-15 | 1990-02-13 | Tatsuo Fujitsuka | Apparatus for anastomosing digestive tract |
US5178634A (en) * | 1989-03-31 | 1993-01-12 | Wilson Ramos Martinez | Aortic valved tubes for human implants |
US5192294A (en) * | 1989-05-02 | 1993-03-09 | Blake Joseph W Iii | Disposable vascular punch |
US5290289A (en) * | 1990-05-22 | 1994-03-01 | Sanders Albert E | Nitinol spinal instrumentation and method for surgically treating scoliosis |
US5088692A (en) * | 1990-09-04 | 1992-02-18 | Weiler Raywood C | Heavy duty staple remover |
US5100421A (en) * | 1991-02-05 | 1992-03-31 | Cyprus Endosurgical Tools, Inc. | Christoudias curved needle suture assembly |
US5868702A (en) * | 1991-07-16 | 1999-02-09 | Heartport, Inc. | System for cardiac procedures |
US5707362A (en) * | 1992-04-15 | 1998-01-13 | Yoon; Inbae | Penetrating instrument having an expandable anchoring portion for triggering protrusion of a safety member and/or retraction of a penetrating member |
US5882340A (en) * | 1992-04-15 | 1999-03-16 | Yoon; Inbae | Penetrating instrument having an expandable anchoring portion for triggering protrusion of a safety member and/or retraction of a penetrating member |
US5499990A (en) * | 1992-05-23 | 1996-03-19 | Forschungszentrum Karlsruhe Gmbh | Suturing instrument |
US5387227A (en) * | 1992-09-10 | 1995-02-07 | Grice; O. Drew | Method for use of a laparo-suture needle |
US5383904A (en) * | 1992-10-13 | 1995-01-24 | United States Surgical Corporation | Stiffened surgical device |
US5382259A (en) * | 1992-10-26 | 1995-01-17 | Target Therapeutics, Inc. | Vasoocclusion coil with attached tubular woven or braided fibrous covering |
US5488958A (en) * | 1992-11-09 | 1996-02-06 | Vance Products Incorporated | Surgical cutting instrument for coring tissue affixed thereto |
US6190373B1 (en) * | 1992-11-13 | 2001-02-20 | Scimed Life Systems, Inc. | Axially detachable embolic coil assembly |
US6036699A (en) * | 1992-12-10 | 2000-03-14 | Perclose, Inc. | Device and method for suturing tissue |
US5855614A (en) * | 1993-02-22 | 1999-01-05 | Heartport, Inc. | Method and apparatus for thoracoscopic intracardiac procedures |
US6346074B1 (en) * | 1993-02-22 | 2002-02-12 | Heartport, Inc. | Devices for less invasive intracardiac interventions |
US6010531A (en) * | 1993-02-22 | 2000-01-04 | Heartport, Inc. | Less-invasive devices and methods for cardiac valve surgery |
US5496334A (en) * | 1993-03-31 | 1996-03-05 | J. Stro/ bel & Sohne GmbH & Co. | Suturing apparatus |
US5282825A (en) * | 1993-06-02 | 1994-02-01 | Muck Kin C | Surgical ligaturing and animal restraining device |
US5500000A (en) * | 1993-07-01 | 1996-03-19 | United States Surgical Corporation | Soft tissue repair system and method |
US5725539A (en) * | 1993-12-01 | 1998-03-10 | Klinikum Der Albert-Ludwigs-Universitat Freiburg | Surgical instrument used to clamp a vessel or the like |
US5486187A (en) * | 1994-01-04 | 1996-01-23 | Schenck; Robert R. | Anastomosis device and method |
US5501692A (en) * | 1994-01-28 | 1996-03-26 | Riza; Erol D. | Laparoscopic suture snare |
US5486197A (en) * | 1994-03-24 | 1996-01-23 | Ethicon, Inc. | Two-piece suture anchor with barbs |
US5715987A (en) * | 1994-04-05 | 1998-02-10 | Tracor Incorporated | Constant width, adjustable grip, staple apparatus and method |
US5881943A (en) * | 1994-06-17 | 1999-03-16 | Heartport, Inc. | Surgical anastomosis apparatus and method thereof |
US5732872A (en) * | 1994-06-17 | 1998-03-31 | Heartport, Inc. | Surgical stapling instrument |
US6176413B1 (en) * | 1994-06-17 | 2001-01-23 | Heartport, Inc. | Surgical anastomosis apparatus and method thereof |
US5709695A (en) * | 1994-08-10 | 1998-01-20 | Segmed, Inc. | Apparatus for reducing the circumference of a vascular structure |
US5720755A (en) * | 1995-01-18 | 1998-02-24 | Dakov; Pepi | Tubular suturing device and methods of use |
US6171321B1 (en) * | 1995-02-24 | 2001-01-09 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US5725542A (en) * | 1995-03-09 | 1998-03-10 | Yoon; Inbae | Multifunctional spring clips and cartridges and applicators therefor |
US6013084A (en) * | 1995-06-30 | 2000-01-11 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils (II) |
US6032849A (en) * | 1995-08-28 | 2000-03-07 | United States Surgical | Surgical stapler |
US5728135A (en) * | 1996-02-09 | 1998-03-17 | Ethicon, Inc. | Stiffened suture for use in a suturing device |
US5709693A (en) * | 1996-02-20 | 1998-01-20 | Cardiothoracic System, Inc. | Stitcher |
US6042607A (en) * | 1996-02-23 | 2000-03-28 | Cardiovascular Technologies Llc | Means and method of replacing a heart valve in a minimally invasive manner |
US5871528A (en) * | 1996-06-28 | 1999-02-16 | Medtronic, Inc. | Temporary bipolar heart wire |
US6024748A (en) * | 1996-07-23 | 2000-02-15 | United States Surgical Corporation | Singleshot anastomosis instrument with detachable loading unit and method |
US5707380A (en) * | 1996-07-23 | 1998-01-13 | United States Surgical Corporation | Anastomosis instrument and method |
US6179848B1 (en) * | 1996-07-24 | 2001-01-30 | Jan Otto Solem | Anastomotic fitting |
US5868763A (en) * | 1996-09-16 | 1999-02-09 | Guidant Corporation | Means and methods for performing an anastomosis |
US6036710A (en) * | 1996-10-04 | 2000-03-14 | United States Surgical | Apparatus for formation of a hole in a blood vessel |
US6171320B1 (en) * | 1996-12-25 | 2001-01-09 | Niti Alloys Technologies Ltd. | Surgical clip |
US5879371A (en) * | 1997-01-09 | 1999-03-09 | Elective Vascular Interventions, Inc. | Ferruled loop surgical fasteners, instruments, and methods for minimally invasive vascular and endoscopic surgery |
US6022367A (en) * | 1997-06-18 | 2000-02-08 | United States Surgical | Surgical apparatus for forming a hole in a blood vessel |
US6346112B2 (en) * | 1997-06-20 | 2002-02-12 | Boston Scientific Corporation | Hemostatic clips |
US6193733B1 (en) * | 1997-06-20 | 2001-02-27 | Boston Scientific Corporation | Hemostatic clips |
US6193734B1 (en) * | 1998-01-23 | 2001-02-27 | Heartport, Inc. | System for performing vascular anastomoses |
US6036703A (en) * | 1998-02-06 | 2000-03-14 | Ethicon Endo-Surgery Inc. | Method and apparatus for establishing anastomotic passageways |
US6176864B1 (en) * | 1998-03-09 | 2001-01-23 | Corvascular, Inc. | Anastomosis device and method |
US6033419A (en) * | 1998-05-15 | 2000-03-07 | Sulzer Carbomedics Inc. | Apparatus and method for cutting a heart valve annulus |
US20070027461A1 (en) * | 1998-06-03 | 2007-02-01 | Barry Gardiner | Tissue connector apparatus and methods |
US20060004389A1 (en) * | 1998-06-03 | 2006-01-05 | Medtronic, Inc. | Multiple loop tissue connector apparatus and methods |
US6517558B2 (en) * | 1999-01-15 | 2003-02-11 | Ventrica, Inc. | Methods and devices for forming vascular anastomoses |
US6350269B1 (en) * | 1999-03-01 | 2002-02-26 | Apollo Camera, L.L.C. | Ligation clip and clip applier |
US6514265B2 (en) * | 1999-03-01 | 2003-02-04 | Coalescent Surgical, Inc. | Tissue connector apparatus with cable release |
US20020010490A1 (en) * | 1999-03-01 | 2002-01-24 | Laurent Schaller | Tissue connector apparatus and methods |
US6695859B1 (en) * | 1999-04-05 | 2004-02-24 | Coalescent Surgical, Inc. | Apparatus and methods for anastomosis |
US6183512B1 (en) * | 1999-04-16 | 2001-02-06 | Edwards Lifesciences Corporation | Flexible annuloplasty system |
US6179849B1 (en) * | 1999-06-10 | 2001-01-30 | Vascular Innovations, Inc. | Sutureless closure for connecting a bypass graft to a target vessel |
US6179840B1 (en) * | 1999-07-23 | 2001-01-30 | Ethicon, Inc. | Graft fixation device and method |
US6197037B1 (en) * | 1999-07-29 | 2001-03-06 | John Hunter Hair | Surgical fastener for joining adjacent bone portions |
US6682540B1 (en) * | 1999-11-05 | 2004-01-27 | Onux Medical, Inc. | Apparatus and method for placing multiple sutures |
US6524338B1 (en) * | 2000-08-25 | 2003-02-25 | Steven R. Gundry | Method and apparatus for stapling an annuloplasty band in-situ |
US20050004582A1 (en) * | 2002-12-16 | 2005-01-06 | Edoga John K. | Endovascular stapler |
US20050021054A1 (en) * | 2003-07-25 | 2005-01-27 | Coalescent Surgical, Inc. | Sealing clip, delivery systems, and methods |
US7182769B2 (en) * | 2003-07-25 | 2007-02-27 | Medtronic, Inc. | Sealing clip, delivery systems, and methods |
US20050043749A1 (en) * | 2003-08-22 | 2005-02-24 | Coalescent Surgical, Inc. | Eversion apparatus and methods |
US20070010835A1 (en) * | 2003-08-22 | 2007-01-11 | Tom Breton | Eversion apparatus and methods |
Also Published As
Publication number | Publication date |
---|---|
US20070010835A1 (en) | 2007-01-11 |
US20050043749A1 (en) | 2005-02-24 |
US8029519B2 (en) | 2011-10-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8029519B2 (en) | Eversion apparatus and methods | |
US7763041B2 (en) | Surgical clips and methods for tissue approximation | |
US6402764B1 (en) | Everter and threadthrough system for attaching graft vessel to anastomosis device | |
US6171321B1 (en) | Devices and methods for performing a vascular anastomosis | |
US8105345B2 (en) | Anastomosis apparatus and methods | |
US7976556B2 (en) | Anastomosis apparatus and methods | |
AU735199B2 (en) | Coronary shunt and method of use | |
US6893449B2 (en) | Device for cutting and anastomosing tissue | |
US7175637B2 (en) | Sutureless closure and deployment system for connecting blood vessels | |
WO1996025886A9 (en) | Devices and methods for performing a vascular anastomosis | |
US6596003B1 (en) | Vascular anastomosis device | |
JP2004528120A (en) | Medical implantation method and device | |
US20050267498A1 (en) | Tissue everting device and method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: MEDTRONIC, INC., MINNESOTA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:COALESCENT SURGICAL, INC.;REEL/FRAME:026680/0626 Effective date: 20040910 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |