US20080281258A1 - Coupling device and medical line set including same - Google Patents
Coupling device and medical line set including same Download PDFInfo
- Publication number
- US20080281258A1 US20080281258A1 US12/176,709 US17670908A US2008281258A1 US 20080281258 A1 US20080281258 A1 US 20080281258A1 US 17670908 A US17670908 A US 17670908A US 2008281258 A1 US2008281258 A1 US 2008281258A1
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- United States
- Prior art keywords
- line set
- coupling device
- connector
- connecting part
- central part
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/288—Priming
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M2039/1061—Break-apart tubing connectors or couplings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/06—Packaging for specific medical equipment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
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- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
Description
- The present invention refers generally to the medical field and specifically to the field of dialysis, such as peritoneal dialysis (PD). More particularly the present invention refers to a medical line set and to a breakable coupling device to be used in such a medical line set. The medical line set may be a peritoneal dialysis line set (PD line set), including a liquid introducing portion connectable with medical supply bags for holding medical solutions, a liquid distribution portion (PD portion) and a drain portion for extracting the solutions, the line set particularly including said coupling device for connecting and disconnecting the liquid introducing portion for introducing and extracting spent medical solution.
- Dialysis is widely used within medical therapy in the treatment of various diseases and disorders. One example is dialysis in the treatment of patients suffering from different stages of acute and chronic renal diseases. These patients are generally treated either by haemodialysis (HD) or peritoneal dialysis PD). During HD the metabolic waste products are cleared by means of an artificial membrane outside the body, whereas during PD the waste products are cleared by means of a biological membrane, such as the peritoneum or peritoneal membrane. There are both manual and automated modes of PD and to find the right treatment mode for each patient, medical, social and economical aspects have to be considered.
- Continuous Ambulatory Peritoneal Dialysis (CAPD) is a frequently used form of PD. It is a manual method where each exchange is taken care of by the patient himself. To increase the efficiency of CAPD and to help the patient with the exchanges, a machine (e.g. a PD cycler) can be used. A PD cycler is a machine that automatically administers all exchanges of PD solutions according to a predetermined schedule. There are different PD applications when using a machine, all summarised with the term APD, Automated Peritoneal Dialysis.
- In the different modes of PD, especially in an APD assembly, a connector is often used to detach a multi-divider tubing system of the PD medical assembly, including the empty PD bags from the PD portion, in order to transfer the empty medical supply bags to the drain portion for discharge of spent PD solution during the following treatment. This is to assist the patient in the situation where there is no sink or the like available for discharge of spent PD solution during the treatment.
- Presently known is an APD system including a standard luer lock connection having a female connecting part and a male connecting part for connecting the liquid introducing portion to the PD portion. The connection is mounted before sterilisation of the whole assembly. After sterilisation and completion of the dialysis procedure the connection is unscrewed and the liquid introducing portion is connected to the drain portion of the next PD medical assembly.
- One major disadvantage with said connection is that the connector tends to get loose during sterilisation as well as during storage and air may be sucked into or leak into the tubing system of the assembly. Air in the system may cause pain to the patient and may even be fatal. Moreover, a loose-fitting connector provides a potential for bacterial contamination of the line set, which in turn may result in serious inflammation of the peritoneum of the patient.
- A further disadvantage with the above construction is, due to the construction of the distinct elements forming the connector ends, that each connector end is required to be manufactured separately, which is time-consuming and increases costs.
- It is towards the need for an improved medical assembly with a safe and simple construction which may be sterilised and stored without the risk of air leakage or bacterial contamination, that the present invention is directed.
- Thus, one object of the invention is to provide a medical line set, including a coupling device, which is safe as regards the risk of air leakage or bacterial contamination after sterilisation and during storage.
- One further object is to provide an improved coupling device for said medical line set which has a simple construction resulting in a low manufacturing cost.
- In order to fulfil the above objects the present invention provides a medical line set having a liquid introducing portion with at least one first connector, a liquid distribution portion with a second connector and a drain portion with a third connector, the line set further comprising a coupling device for connecting the liquid introducing portion to the liquid distribution portion, said coupling device having
- a first connecting part connectable with the liquid distribution portion;
a central part;
a second connecting part connectable with the liquid introducing portion, the central part and the second connecting part being integrally formed with the first connecting part; and
a predetermined breaking section between the central part and the first connecting part. - In one aspect of the invention the medical line set is a PD line set and in a preferred aspect it is an APD line set.
- According to the present invention there is also provided a coupling device, which is particularly useful in a medical dialysis line set having a liquid introducing portion with at least one first connector, a liquid distribution portion with a second connector and a drain portion with a third connector for connecting the liquid introducing portion to the liquid distribution portion, said coupling device comprising
- a first connecting part connectable with the liquid distribution portion;
a central part;
a second connecting part connectable with the liquid introducing portion, the central part and the second connecting part being integrally formed with the first connecting part; and
a predetermined breaking section between the central part and the first connecting part. - In a preferred embodiment the central part of the coupling device of said medical line set is adapted to be connectable with the third connector.
- In a further preferred embodiment the predetermined breaking section of the coupling device of said medical line set is defined by a groove in the junction between the central part and the first connecting part and is breakable at finger pressure.
- In one aspect the coupling device is adapted to be used in a PD line set and in a preferred aspect it is adapted to be used in an APD line set.
- Moreover, the present invention provides a method for performing dialysis in a medical line set having a liquid introducing portion with at least one first connector, a liquid distribution portion with a second connector and a drain portion with a third connector, the line set further comprising a coupling device for connecting the liquid introducing portion to the liquid distribution portion.
- According to a preferred aspect the method refers to a method of performing dialysis in an PD line set and more preferably in an APD line set.
- By means of the present invention the risk for patients on dialysis to be harmed due to air leakage into the system or bacterial contamination thereof is minimised. A further benefit provided by the present invention is that the coupling device is easy to produce and easy to mount, which makes the coupling device, as well as the medical line set including the coupling device, safe and economical. Moreover, by manufacturing the coupling device as an integrated moulded product, the cost of manufacturing the PD tubing set is decreased.
-
FIG. 1 is a schematic view of a medical line set according to the present invention including a coupling device according to the invention; -
FIG. 2 is a front view of a coupling device according to the present invention; and -
FIG. 3 is a cross sectional view of a coupling device according to the present invention. - The medical line set according to the invention has a liquid introducing portion, a liquid distribution portion, a drain portion and a coupling device for connecting the liquid introducing portion to the liquid distribution portion.
- The medical line set of the invention is preferably a medical dialysis line set, such as a PD line set and more particularly an APD line set.
- Referring to
FIG. 1 one embodiment of a medical line set according to the present invention is shown. The medical line set 10 is a medical line set for APD. TheAPD line set 10 includes aliquid introducing portion 20, a liquid distribution portion orPD portion 40, adrain portion 80 and acoupling device 90. According to the embodiment shown inFIG. 1 thecoupling device 90 is placed between theliquid introducing portion 20 and theliquid distribution portion 40. Thecoupling device 90 has a first connectingpart 92, asecond connecting part 94 and acentral part 96. The first connectingpart 92 of thecoupling device 90 is connected to theliquid distribution portion 40 and the second connectingpart 94 of thecoupling device 90 is connected to theliquid introducing portion 20. - The
liquid introducing portion 20 includesconnection tubes 22 with clamps 26 a and one or morefirst connectors 24 adapted for the introduction of different medical solutions from medical supply bags (not shown). Theliquid introducing portion 20 further includes adistributor 28 and afirst feed line 30 for delivering the medical solutions to theliquid distribution portion 40. - The
liquid distribution portion 40 includes according to the embodiment shown inFIG. 1 aheater bag 54 and adrain bag 56. Theheater bag 54 is used for the medical solution, e.g. a PD solution, to be preheated, weighted and introduced into the patient and thedrain bag 56 is intended for the spent PD solution being extracted from the patient after the peritoneal dialysis is finished. - In connection with the
heater bag 54 there is provided asecond feed line 42, adose valve 46, a first F-connector 44, athird feed line 50 provided with a clamp 26 b and a first seal 52 a for introducing medical solutions from theliquid introducing portion 20 to theheater bag 54. Liquid from theheater bag 54 flows into a patient via aninflow valve 48, aninflow line 58, a Y-connector 62, apatient line 64 provided with a clamp 26 d and aninjection port 68, and asecond connector 66 attached to a PD catheter (not shown) entered into the peritoneal cavity of the patient. - In connection with the
drain bag 56 of theliquid distribution portion 40 there is provided a second seal 52 b, afirst drain line 74, a second F-connector 72, asampling port 76 and anoutflow line 60 having anoutflow valve 70 for allowing liquid to flow, on one hand, from the patient to thedrain bag 56 and, on the other hand, from thedrain bag 56 to thedrain portion 80. - The
drain portion 80 of the medical line set 10 includes asecond drain line 84, having adrain valve 82 and a clamp 26 c, and athird connector 86. Saidthird connector 86 is adapted to be connectable with thecoupling device 90 for discharge of used PD solution. - According to a preferred embodiment the
coupling device 90 and thethird connector 86 are both standard luer lock or luer cone connectors. -
- The present invention also refers to a coupling device which may be used in a medical line set as described above.
- Referring now to
FIGS. 2 and 3 there is shown one embodiment of a coupling device according to the invention. Thecoupling device 90 has a first connectingpart 92, acentral part 96 and a second connectingpart 94. These threeparts - The
central part 96 is provided with apredetermined breaking section 100 defined by a circumferential groove in the junction between thecentral part 96 and the first connectingpart 92. Thecoupling device 90 is adapted to be broken along thispredetermined breaking section 100 into two pieces. The thickness of the material of thebreaking section 100 is such that thebreaking section 100 may be broken when either of the first connectingpart 92 and the second connectingpart 94 is twisted or bent. Thebreaking section 100 is breakable at finger pressure. - Furthermore, the
central part 96 of thecoupling device 90 is preferably provided withthreads 98 along the whole or part of its length. With reference toFIG. 2 acoupling device 90 is shown wherein thecentral part 96 is provided withthreads 98 along part of its length, i.e. the part close to the breaking section. In order to facilitate the manufacturing of thecoupling device 90 as an integral piece thethreads 98 of the central part may, as shown inFIG. 2 , be divided into two parts along the circumference of thecentral part 96. As appears fromFIG. 2 part of the threads may be bevelled resulting in bevelled surfaces 102. Alternatively, the threads may be distinctly divided into two or more groups. - In the embodiment shown in
FIGS. 2 and 3 , thecentral part 96 is shaped in the form of a male luer cone having standard luer cone dimensions. Said standard dimensions of a male luer cone connector is as follows: the connection diameter is 4.29 mm and the length of the cone is at least 7.5 mm with a cone angle of 1°43′6″ towards the smallest diameter of the luer cone. The connection diameter of the luer cone is, with reference toFIG. 2 , the diameter adjacent the first connectingpart 92 at thepredetermined breaking section 100 and the smallest diameter of the luer cone is the one adjacent the second connectingpart 94. - The second connecting
part 94 is preferably provided with two or moregripping surfaces 104 for twisting said second connectingpart 94 around its axis with the fingers in order to separate the second connectingpart 94 and thecentral part 96 from the first connectingpart 92. The second connectingpart 94 of thecoupling device 90 shown inFIG. 2 is provided with four gripping surfaces regularly arranged around said second connectingpart 94. While any number of gripping surfaces may be provided, the number is suitably at least two. - Preferably the coupling device has the form of a luer lock connector, the central part thereof having the form of a male luer cone.
-
- According to another embodiment the luer cone luer lock connector may be presented without threads, the central part having the form of a male luer cone adapted to be pressed into a mating female luer connector.
- Moreover, the present coupling device may have any suitable dimensions as long as it is adapted to be coupled to a mating connector, shown as the
third connector 86 inFIG. 1 . Thecentral part 96 may e.g. vary in length. - Breaking the
present coupling device 90 along thepredetermined breaking section 100 results in two pieces, one piece comprising the threaded part or the cone formed part to be the drain portion, i.e. thecentral part 96 and the second connectingpart 94, and connected to the other piece comprising the first connectingpart 92. - The coupling device of the present invention is produced in one piece through any suitable known technique, such as injection moulding and form pressing. The coupling device may be made of any suitable material, e.g. thermoplastic polymers, such as polyvinyl chloride, polystyrene and polyurethane, or combinations thereof.
- According to a preferred embodiment the coupling device according to the invention is made of polyvinyl chloride by injection moulding under standard process conditions well known within the art.
- The method for performing dialysis in a dialysis line set according to the present invention is described with reference to
FIG. 1 . It implies the use of a medical line set 10 having aliquid introducing portion 20 with at least onefirst connector 24, a liquid distribution portion orPD portion 40 with aheater bag 54, adrain bag 56 and asecond connector 66, and adrain portion 80 with athird connector 86, the line set further comprising acoupling device 90 having a first connectingpart 92 connectable with theliquid distribution portion 40; acentral part 96 adapted to be connected with thethird connector 86; a second connectingpart 94 connectable with theliquid introducing portion 20, thecentral part 96 and the second connectingpart 94 being integrally formed with the first connectingpart 92; and apredetermined breaking section 100 defined by a groove in the junction between thecentral part 96 and the first connectingpart 92 and being breakable at finger pressure. Said method comprises the steps of - introducing a PD solution via the
liquid introducing portion 20 into theheater bag 54 to prepare a predetermined dose of the PD solution;
introducing said dose of PD solution into the peritoneal cavity of a patient;
allowing the predetermined dose of PD solution to reside in the peritoneal cavity of the patient for a predetermined dwell period;
extracting the used PD solution from peritoneal cavity of the patient and allowing said used solution to enter thedrain bag 56;
separating theliquid introducing portion 20 from theliquid distribution portion 40 through breaking thepredetermined breaking section 100, thus separating thecentral part 96 and the second connectingpart 94 of the coupling device from the first connectingpart 92; and
connecting thecentral part 96 and the second connectingpart 94 to thethird connector 86 of thedrain portion 80 for draining the used PD solution via thedrain portion 80 to the medical supply bags (not shown). - The coupling device and the medical line set of the invention is preferably used in an APD system, but may also be used in other systems, having the need for a coupling device according to the invention.
- The function of a medical line set according to the invention will now be described with reference to the embodiment shown in
FIG. 1 , wherein the medical line set is an APD medical line set. - First a sterile medical line set 10 is mounted on a PD cycler (not shown). The PD cycler includes four valves,
dose valve 46,inflow valve 48,outflow valve 70 anddrain valve 82, which are all initially closed. The liquid flow on the PD cycler can be created optional, by e.g. gravitation, in a pressure chamber, with a pump etc. Clamps 26 a,b,c,d of the PD medical line set 10 shall now be closed. Thefirst connectors 24, which may be screw connectors, piercing connectors etc., are attached to medical supply bags (not shown) including for the treatment required solutions. The liquid introducing portion of a medical PD line set used in a previous treatment (not shown) is attached to thethird connector 86 of thedrain portion 80. Now the clamps 26 a are opened and the PD medical line set is automatically primed with PD solution. Thedose valve 46 of the PD cycler and clamp 26 b are opened and liquid from the medical supply bags flows through first andsecond feed lines connector 44 and thethird feed line 50 to theheater bag 54 to prepare a required and predetermined dose of a PD solution. When the required dose has been filled into theheater bag 54 thedose valve 46 is closed. In the meantime thesecond connector 66 is connected to a PD catheter (not shown) of a patient to be treated. The PD solution in theheater bag 54 is heated to around body temperature and weighed a first time to define a first weight. Theinflow valve 48 and the clamp 26 d are opened and the PD solution is allowed to flow through theinflow line 58 and thepatient line 64 into the peritoneal cavity of the patient via thesecond connector 66 and the PD catheter of the patient. When the required dose of PD solution has been distributed to the patient theinflow valve 48 is closed. Theinjection port 68 on thepatient line 64 may be used for injecting into the patient any further solution, substance, etc. such as insulin and antibiotics. Alternatively, it may be used for taking samples, such as samples of the spent PD solution. - After a predetermined dwell period, i.e. the time during which the PD solution is residing in the peritoneal cavity without being administered or drained and during which time the dialysis exchange is taking place, the
outflow valve 70 is opened and the spent PD solution is allowed to enter thedrain bag 56 throughpatient line 64,outflow line 60, second F-connector 72 andfirst drain line 74. Theoutflow valve 70 is closed, the spent PD solution, now in thedrain bag 56, is weighed a second time to define a second weight. Said second weight is compared to the first weight of theheater bag 54 and the difference between the two weights is calculated for monitoring and controlling the treatment. Thesampling port 76 may be used for taking samples of the spent PD solution. - Finally, the
drain valve 82 and the clamp 26 c are opened and the spent and weighed PD solution is drained through thesecond drain line 84 into the empty medical supply bags used in a previous treatment and attached via thethird connector 86. After completion of a treatment theliquid introduction portion 20 of the medical PD line set used in the previous treatment is disconnected from thethird connector 86 of thedrain portion 80 and discarded. In this final step thecoupling device 90 of the now used medical line set (10) is separated into two pieces, one piece comprising the first connectingpart 92 and the other piece comprising the second connectingpart 94 and thecentral part 96, by breaking thepredetermined breaking section 100 through twisting or bending either of the connecting parts. The resulting second connectingpart 94 together with thecentral part 96 having the shape of a luer lock is then connected to the matingthird connector 86, which has the form of a mating luer lock. In general the patient does not separate the coupling device into two pieces, thus moving the liquid introducing portion to the drain portion, until just before the next treatment. - The medical line set including the coupling device according to the invention may, if needed and suitable, include two or more of said coupling devices.
- One example of liquid used in the medical line set according to the invention is a PD solution and it may be any PD solution known in the art.
- The integrally formed coupling device of the invention is easy, safe and economic to manufacture. Moreover, mounting of the coupling device is easy and safe. Being formed in one piece the coupling device is safe from air-leakage and bacterial contamination after sterilisation and during storage.
- A preferred embodiment of the invention has been described. However, many variations of the invention, which are within the spirit and scope of the invention as claimed in the following claims, may be made.
-
- 10 medical line set
- 20 liquid introducing portion
- 22 connection tube
- 24 first connector
- 26 a,b,c,d clamp
- 28 distributor
- 30 feed line, first
- 40 liquid distribution portion/PD portion
- 42 second feed line
- 44 first F-connector
- 46 dose valve
- 48 inflow valve
- 50 third feed line
- 52 a,b seal
- 54 heater bag
- 56 drain bag
- 58 inflow line
- 60 outflow line
- 62 Y-connector
- 64 patient line
- 66 second connector
- 68 Injection port
- 70 outflow valve
- 72 second F-connector
- 74 first drain line
- 76 sampling port
- 80 drain portion
- 82 drain valve
- 84 second drain line
- 86 third connector
- 90 coupling device
- 92 first connecting part
- 94 second connecting part
- 96 central part
- 98 thread
- 100 predetermined breaking section
- 102 bevelled surface
- 104 gripping surface
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/176,709 US20080281258A1 (en) | 2001-01-08 | 2008-07-21 | Coupling device and medical line set including same |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0100043A SE523860C2 (en) | 2001-01-08 | 2001-01-08 | Coupling device and medical wiring set with such coupling device |
SE0100043-9 | 2001-01-08 | ||
US10/250,482 US7452346B2 (en) | 2001-01-08 | 2001-12-19 | Coupling device and medical line set including same |
PCT/SE2001/002813 WO2002053211A1 (en) | 2001-01-08 | 2001-12-19 | Coupling device and medical line set including same |
US12/176,709 US20080281258A1 (en) | 2001-01-08 | 2008-07-21 | Coupling device and medical line set including same |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE2001/002813 Division WO2002053211A1 (en) | 2001-01-08 | 2001-12-19 | Coupling device and medical line set including same |
US10/250,482 Division US7452346B2 (en) | 2001-01-08 | 2001-12-19 | Coupling device and medical line set including same |
Publications (1)
Publication Number | Publication Date |
---|---|
US20080281258A1 true US20080281258A1 (en) | 2008-11-13 |
Family
ID=20282566
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/250,482 Expired - Lifetime US7452346B2 (en) | 2001-01-08 | 2001-12-19 | Coupling device and medical line set including same |
US12/176,709 Abandoned US20080281258A1 (en) | 2001-01-08 | 2008-07-21 | Coupling device and medical line set including same |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/250,482 Expired - Lifetime US7452346B2 (en) | 2001-01-08 | 2001-12-19 | Coupling device and medical line set including same |
Country Status (9)
Country | Link |
---|---|
US (2) | US7452346B2 (en) |
EP (1) | EP1351726B1 (en) |
JP (1) | JP4009194B2 (en) |
KR (1) | KR100813371B1 (en) |
AT (1) | ATE354385T1 (en) |
DE (1) | DE60126826T2 (en) |
ES (1) | ES2282199T3 (en) |
SE (1) | SE523860C2 (en) |
WO (1) | WO2002053211A1 (en) |
Cited By (1)
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WO2020164038A1 (en) * | 2019-02-14 | 2020-08-20 | Fresenius Medical Care Deutschland Gmbh | Anti-contamination adapter, connector, set for peritoneal dialysis, and use thereof in peritoneal dialysis |
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Also Published As
Publication number | Publication date |
---|---|
SE0100043L (en) | 2002-07-09 |
DE60126826D1 (en) | 2007-04-05 |
US20040067161A1 (en) | 2004-04-08 |
KR100813371B1 (en) | 2008-03-12 |
US7452346B2 (en) | 2008-11-18 |
KR20040004488A (en) | 2004-01-13 |
ES2282199T3 (en) | 2007-10-16 |
SE523860C2 (en) | 2004-05-25 |
EP1351726A1 (en) | 2003-10-15 |
DE60126826T2 (en) | 2007-06-28 |
EP1351726B1 (en) | 2007-02-21 |
WO2002053211A1 (en) | 2002-07-11 |
JP2004516894A (en) | 2004-06-10 |
SE0100043D0 (en) | 2001-01-08 |
ATE354385T1 (en) | 2007-03-15 |
JP4009194B2 (en) | 2007-11-14 |
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