US20070270750A1 - Drug delivery device - Google Patents
Drug delivery device Download PDFInfo
- Publication number
- US20070270750A1 US20070270750A1 US11/435,906 US43590606A US2007270750A1 US 20070270750 A1 US20070270750 A1 US 20070270750A1 US 43590606 A US43590606 A US 43590606A US 2007270750 A1 US2007270750 A1 US 2007270750A1
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- US
- United States
- Prior art keywords
- handpiece
- tip
- drug
- delivery device
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8262—Internal energy supply devices connectable to external power source, e.g. connecting to automobile battery through the cigarette lighter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/484—Regulating injection pressure
Definitions
- the present invention generally pertains to the delivery of ophthalmically acceptable pharmaceutically active agents to the back of the eye and more particularly to an apparatus for delivery of precise amounts of a liquid or phase transition drug under controlled back pressure and flow conditions.
- Age related macular degeneration is the leading cause of blindness in the elderly. It attacks the center of vision and blurs it, making reading, driving, and other detailed tasks difficult or impossible. Current estimates reveal that approximately forty percent of the population over age 75, and approximately twenty percent of the population over age 60, suffer from some degree of macular degeneration. In “wet” ARMD, the type that most often causes blindness, newly formed choroidal blood vessels (CNV) leak fluid and cause progressive damage to the retina. Two main methods of treatment are currently being performed, (a) photocoagulation and (b) the use of angiogenesis inhibitors.
- CNV choroidal blood vessels
- Photocoagulation can be harmful to the retina and is impractical when the CNV is in proximity of the fovea. Furthermore, photocoagulation often results in recurrent CNV over time.
- Angiogenesis inhibitors may be administered orally, by intraocular injections, by extraocular sub-Tennon injections, or by local implants.
- a physician disposes the tip of a curved needle externally around the eye near the macula, and releases a precise amount of the drug.
- a concern with sub-Tenon delivery is that the drug must be administered slowly and under relatively low pressure so as to be retained in the tissue rather than leaking back out, around the needle.
- the present invention improves upon the prior art by providing a syringe-like device having a drug dispensing tip connected to a motorized handpiece.
- the tip may be packaged pre-loaded with an amount of a liquid or phase transition drug or may be shipped empty and loaded with a liquid or phase transition drug by the user.
- the motorized handpiece contains suitable sensors and controllers for precisely actuating the tip for the controlled delivery of the liquid or phase transition drug in the tip.
- the handpiece may contain an internal power source, such as a battery, or may be connected to an external power source and/or control unit.
- one objective of the present invention is to provide a syringe-like device having a drug dispensing tip.
- Another objective of the present invention is to provide a device for the delivery of a drug to the human eye and having a drug dispensing tip actuated by a motorized handpiece.
- Yet another objective of the present invention is to provide a drug delivery device wherein the flow rate of the drug being delivered can be controlled.
- FIG. 1 is an enlarged, schematical view of a first embodiment of the drug deliver device of the present invention.
- FIG. 2 is an enlarged, schematical view of a second embodiment of the drug deliver device of the present invention.
- drug delivery device 10 of the present invention generally comprises tip 12 and handpiece 14 .
- Tip 12 generally contains delivery cannula or needle 16 and body 18 .
- Needle 16 may be any suitably sized needle of conventional construction.
- Body 18 generally is of a construction similar to a standard hypodermic syringe, e.g., cylindrical and tubular, made from glass, metal or a suitable plastic. Body 18 is sized and shaped to hold a suitable amount of a liquid or phase transition drug.
- Handpiece 14 generally is sized and shape similar to body 18 , e.g., cylindrical, and has distal end 20 adapted to allow tip 12 to be mechanically connected to handpiece 14 .
- Handpiece 14 contains drive mechanism 22 , with associated driver electronics 24 , to push plunger 21 in body 18 to force the liquid or phase transition drug contained in body 18 out needle 16 .
- Suitable drive mechanisms include, for example, piezoelectric linear motors, such motors being well-known in the art (as described in U.S. Pat. No. 6,940,209 (Henderson)), and available from sources such as New Scale Technologies, Inc., Victor, N.Y.
- power for driver 22 and control electronics 24 is provided from power source 26 , such as a battery, located internal to handpiece 14 .
- power source 26 such as a battery, located internal to handpiece 14 .
- electronics 24 can provide a feedback mechanism that senses the back pressure being exerted against the expression of the drug out of needle 16 and make appropriate adjustments to the speed and direction of motor 22 .
- drug delivery device 110 of the present invention may also generally comprise tip 112 and handpiece 114 .
- Tip 112 generally contains delivery cannula or needle 116 and body 118 .
- Needle 116 may be any suitably sized needle of conventional construction.
- Body 118 is generally is of construction similar to a standard hypodermic syringe, e.g., cylindrical and tubular, made from glass, metal or a suitable plastic. Body 118 is sized and shaped to hold a suitable amount of a liquid or phase transition drug.
- Handpiece 114 generally is sized and shaped similar to body 118 , e.g., cylindrical, and has distal end 120 adapted so allow tip 112 to be mechanically connected to handpiece 114 .
- Handpiece 114 contains drive mechanism 122 , with associated driver electronics 124 , to push plunger 121 in body 118 to force the liquid or phase transition drug contained in body 118 out needle 116 .
- control electronics 124 are located external to handpiece 114 and power and control signals are provided to drive mechanism 122 through cable 123 .
- Power for driver 122 and electronics 124 is provided from external source 126 through electrical cable 128 . Such a construction allows for a smaller handpiece 114 .
Abstract
A syringe-like device having a drug dispensing tip connected to a motorized handpiece. The tip may be packaged pre-loaded with an amount of a liquid or phase transition drug or may be shipped empty and loaded with a liquid or phase transition drug by the user. The motorized handpiece contains suitable sensors and controllers for precisely actuating the tip for the controlled delivery of the liquid or phase transition drug in the tip. The handpiece by contain an internal power source, such as a battery, or may be connected to an external power source and/or control unit.
Description
- The present invention generally pertains to the delivery of ophthalmically acceptable pharmaceutically active agents to the back of the eye and more particularly to an apparatus for delivery of precise amounts of a liquid or phase transition drug under controlled back pressure and flow conditions.
- Age related macular degeneration (ARMD) is the leading cause of blindness in the elderly. It attacks the center of vision and blurs it, making reading, driving, and other detailed tasks difficult or impossible. Current estimates reveal that approximately forty percent of the population over age 75, and approximately twenty percent of the population over age 60, suffer from some degree of macular degeneration. In “wet” ARMD, the type that most often causes blindness, newly formed choroidal blood vessels (CNV) leak fluid and cause progressive damage to the retina. Two main methods of treatment are currently being performed, (a) photocoagulation and (b) the use of angiogenesis inhibitors.
- Photocoagulation can be harmful to the retina and is impractical when the CNV is in proximity of the fovea. Furthermore, photocoagulation often results in recurrent CNV over time.
- Angiogenesis inhibitors may be administered orally, by intraocular injections, by extraocular sub-Tennon injections, or by local implants. In the sub-Tenon injection method, a physician disposes the tip of a curved needle externally around the eye near the macula, and releases a precise amount of the drug. However, a concern with sub-Tenon delivery is that the drug must be administered slowly and under relatively low pressure so as to be retained in the tissue rather than leaking back out, around the needle.
- Therefore, a need exists in the field of ophthalmology for an improved apparatus for controlled delivery of a drug to the human eye.
- The present invention improves upon the prior art by providing a syringe-like device having a drug dispensing tip connected to a motorized handpiece. The tip may be packaged pre-loaded with an amount of a liquid or phase transition drug or may be shipped empty and loaded with a liquid or phase transition drug by the user. The motorized handpiece contains suitable sensors and controllers for precisely actuating the tip for the controlled delivery of the liquid or phase transition drug in the tip. The handpiece may contain an internal power source, such as a battery, or may be connected to an external power source and/or control unit.
- Accordingly, one objective of the present invention is to provide a syringe-like device having a drug dispensing tip.
- Another objective of the present invention is to provide a device for the delivery of a drug to the human eye and having a drug dispensing tip actuated by a motorized handpiece.
- Yet another objective of the present invention is to provide a drug delivery device wherein the flow rate of the drug being delivered can be controlled.
- Yet another objective of the present invention is to provide a drug delivery device wherein the amount of the drug being delivered can be controlled.
- These and other advantages and objectives of the present invention will become apparent from the detailed description and claims that follow.
-
FIG. 1 is an enlarged, schematical view of a first embodiment of the drug deliver device of the present invention. -
FIG. 2 is an enlarged, schematical view of a second embodiment of the drug deliver device of the present invention. - As best seen in
FIG. 1 ,drug delivery device 10 of the present invention generally comprisestip 12 andhandpiece 14.Tip 12 generally contains delivery cannula orneedle 16 andbody 18.Needle 16 may be any suitably sized needle of conventional construction.Body 18 generally is of a construction similar to a standard hypodermic syringe, e.g., cylindrical and tubular, made from glass, metal or a suitable plastic.Body 18 is sized and shaped to hold a suitable amount of a liquid or phase transition drug.Handpiece 14 generally is sized and shape similar tobody 18, e.g., cylindrical, and hasdistal end 20 adapted to allowtip 12 to be mechanically connected tohandpiece 14.Handpiece 14 containsdrive mechanism 22, with associateddriver electronics 24, to pushplunger 21 inbody 18 to force the liquid or phase transition drug contained inbody 18 outneedle 16. Suitable drive mechanisms include, for example, piezoelectric linear motors, such motors being well-known in the art (as described in U.S. Pat. No. 6,940,209 (Henderson)), and available from sources such as New Scale Technologies, Inc., Victor, N.Y. In the embodiment illustrated inFIG. 1 , power fordriver 22 andcontrol electronics 24 is provided frompower source 26, such as a battery, located internal tohandpiece 14. Such a construction allows for very precise and controlled movement ofplunger 21. In addition,electronics 24 can provide a feedback mechanism that senses the back pressure being exerted against the expression of the drug out ofneedle 16 and make appropriate adjustments to the speed and direction ofmotor 22. - As best seen in
FIG. 2 ,drug delivery device 110 of the present invention may also generally comprisetip 112 andhandpiece 114.Tip 112 generally contains delivery cannula or needle 116 andbody 118. Needle 116 may be any suitably sized needle of conventional construction.Body 118 is generally is of construction similar to a standard hypodermic syringe, e.g., cylindrical and tubular, made from glass, metal or a suitable plastic.Body 118 is sized and shaped to hold a suitable amount of a liquid or phase transition drug.Handpiece 114 generally is sized and shaped similar tobody 118, e.g., cylindrical, and hasdistal end 120 adapted so allowtip 112 to be mechanically connected tohandpiece 114.Handpiece 114 containsdrive mechanism 122, with associateddriver electronics 124, to pushplunger 121 inbody 118 to force the liquid or phase transition drug contained inbody 118 out needle 116. In the embodiment illustrated inFIG. 2 ,control electronics 124 are located external tohandpiece 114 and power and control signals are provided to drivemechanism 122 throughcable 123. Power fordriver 122 andelectronics 124 is provided fromexternal source 126 throughelectrical cable 128. Such a construction allows for asmaller handpiece 114. - This description is given for purposes of illustration and explanation. It will be apparent to those skilled in the relevant art that changes and modifications may be made to the invention described above without departing from its scope or spirit.
Claims (6)
1. A drug delivery device, comprising:
a) a handpiece;
b) a tip having a body, the body being removably attached to the handpiece;
c) a cannula generally located on the body opposite the handpiece;
d) a plunger located in the tip body; and
e) a drive mechanism located in the handpiece, the drive mechanism providing movement of the plunger when the tip is connected to the handpiece.
2. The drug delivery device of claim 1 wherein the drive mechanism comprises a piezoelectric linear motor.
3. The drug delivery device of claim 1 wherein the handpiece further comprises an internal power source for the drive mechanism.
4. The drug delivery device of claim 1 wherein the handpiece further comprises internal control electronics for the drive mechanism.
5. The drug delivery device of claim 1 further comprising external control electronics for the drive mechanism.
6. The drug delivery device of claim 1 wherein the handpiece further comprises an external power source for the drive mechanism.
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/435,906 US20070270750A1 (en) | 2006-05-17 | 2006-05-17 | Drug delivery device |
US11/688,573 US7811252B2 (en) | 2006-05-17 | 2007-03-20 | Dosage control device |
CA002588519A CA2588519A1 (en) | 2006-05-17 | 2007-05-15 | Drug delivery device |
EP07108293A EP1857130A1 (en) | 2006-05-17 | 2007-05-15 | Drug delivery device |
TW096117365A TW200744558A (en) | 2006-05-17 | 2007-05-16 | Drug delivery device |
MX2007005846A MX2007005846A (en) | 2006-05-17 | 2007-05-16 | Drug delivery device. |
BRPI0702340-5A BRPI0702340A (en) | 2006-05-17 | 2007-05-16 | drug delivery device |
ARP070102129A AR061002A1 (en) | 2006-05-17 | 2007-05-17 | FARMACOS ADMINISTRATION DEVICE |
KR1020070048065A KR20070111394A (en) | 2006-05-17 | 2007-05-17 | Drug delivery device |
AU2007202216A AU2007202216A1 (en) | 2006-05-17 | 2007-05-17 | Drug delivery device |
IL183295A IL183295A0 (en) | 2006-05-17 | 2007-05-17 | Drug delivery device |
CNA200710104927XA CN101073682A (en) | 2006-05-17 | 2007-05-17 | Medicine conveying device |
JP2007131544A JP2007307376A (en) | 2006-05-17 | 2007-05-17 | Drug delivery device |
US11/752,064 US7862540B2 (en) | 2006-05-17 | 2007-05-22 | Ophthalmic injection device using shape memory alloy |
US11/751,934 US20070268340A1 (en) | 2006-05-17 | 2007-05-22 | Ophthalmic Injection System and Method Using Piezoelectric Array |
US11/751,981 US7674243B2 (en) | 2006-05-17 | 2007-05-22 | Ophthalmic injection device using piezoelectric array |
US11/752,011 US20070270768A1 (en) | 2006-05-17 | 2007-05-22 | Mechanical Linkage Mechanism For Ophthalmic Injection Device |
US11/762,844 US7762981B2 (en) | 2006-05-17 | 2007-06-14 | Temperature release mechanism for injection device |
US11/777,408 US8821440B2 (en) | 2006-05-17 | 2007-07-13 | Dual thermal coefficient dispensing chamber |
US11/832,301 US7887521B2 (en) | 2006-05-17 | 2007-08-01 | Ophthalmic injection system |
US11/832,333 US7815603B2 (en) | 2006-05-17 | 2007-08-01 | Ophthalmic injection method |
US11/832,364 US20070270744A1 (en) | 2006-05-17 | 2007-08-01 | Limited Reuse Assembly For Ophthalmic Injection Device |
US11/832,243 US7871399B2 (en) | 2006-05-17 | 2007-08-01 | Disposable ophthalmic injection device |
US11/833,471 US20080021412A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage and Seal For Ophthalmic Medical Device |
US11/833,668 US7887517B2 (en) | 2006-05-17 | 2007-08-03 | Drug casting |
US11/833,518 US20080021419A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage Method For Ophthalmic Medical Device |
PCT/US2007/080505 WO2008105954A2 (en) | 2006-05-17 | 2007-10-05 | Disposable ophthalmic injection device |
PCT/US2007/080673 WO2008105956A2 (en) | 2006-05-17 | 2007-10-08 | Ophthalmic injection method |
US12/443,898 US8118790B2 (en) | 2006-05-17 | 2007-10-09 | Battery operated surgical hand piece with disposable end |
US12/109,079 US20080197035A1 (en) | 2006-05-17 | 2008-04-24 | Sharps Container System for Two Piece Injection Device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/435,906 US20070270750A1 (en) | 2006-05-17 | 2006-05-17 | Drug delivery device |
Related Child Applications (15)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US92149706P Continuation-In-Part | 2006-05-17 | 2006-10-16 | |
US58162906A Continuation-In-Part | 2006-05-17 | 2006-10-16 | |
US11/688,573 Continuation-In-Part US7811252B2 (en) | 2006-05-17 | 2007-03-20 | Dosage control device |
US11/752,064 Continuation-In-Part US7862540B2 (en) | 2006-05-17 | 2007-05-22 | Ophthalmic injection device using shape memory alloy |
US11/762,844 Continuation-In-Part US7762981B2 (en) | 2006-05-17 | 2007-06-14 | Temperature release mechanism for injection device |
US11/777,408 Continuation-In-Part US8821440B2 (en) | 2006-05-17 | 2007-07-13 | Dual thermal coefficient dispensing chamber |
US11/832,301 Continuation-In-Part US7887521B2 (en) | 2006-05-17 | 2007-08-01 | Ophthalmic injection system |
US11/832,333 Continuation-In-Part US7815603B2 (en) | 2006-05-17 | 2007-08-01 | Ophthalmic injection method |
US11/832,243 Continuation-In-Part US7871399B2 (en) | 2006-05-17 | 2007-08-01 | Disposable ophthalmic injection device |
US11/832,364 Continuation-In-Part US20070270744A1 (en) | 2006-05-17 | 2007-08-01 | Limited Reuse Assembly For Ophthalmic Injection Device |
US11/833,518 Continuation-In-Part US20080021419A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage Method For Ophthalmic Medical Device |
US11/833,668 Continuation-In-Part US7887517B2 (en) | 2006-05-17 | 2007-08-03 | Drug casting |
US11/833,471 Continuation-In-Part US20080021412A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage and Seal For Ophthalmic Medical Device |
US12/443,898 Continuation-In-Part US8118790B2 (en) | 2006-05-17 | 2007-10-09 | Battery operated surgical hand piece with disposable end |
US12/109,079 Continuation-In-Part US20080197035A1 (en) | 2006-05-17 | 2008-04-24 | Sharps Container System for Two Piece Injection Device |
Publications (1)
Publication Number | Publication Date |
---|---|
US20070270750A1 true US20070270750A1 (en) | 2007-11-22 |
Family
ID=38420664
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/435,906 Abandoned US20070270750A1 (en) | 2006-05-17 | 2006-05-17 | Drug delivery device |
US11/762,844 Expired - Fee Related US7762981B2 (en) | 2006-05-17 | 2007-06-14 | Temperature release mechanism for injection device |
US11/777,408 Expired - Fee Related US8821440B2 (en) | 2006-05-17 | 2007-07-13 | Dual thermal coefficient dispensing chamber |
US11/833,471 Abandoned US20080021412A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage and Seal For Ophthalmic Medical Device |
US11/833,668 Expired - Fee Related US7887517B2 (en) | 2006-05-17 | 2007-08-03 | Drug casting |
US11/833,518 Abandoned US20080021419A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage Method For Ophthalmic Medical Device |
US12/109,079 Abandoned US20080197035A1 (en) | 2006-05-17 | 2008-04-24 | Sharps Container System for Two Piece Injection Device |
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US11/762,844 Expired - Fee Related US7762981B2 (en) | 2006-05-17 | 2007-06-14 | Temperature release mechanism for injection device |
US11/777,408 Expired - Fee Related US8821440B2 (en) | 2006-05-17 | 2007-07-13 | Dual thermal coefficient dispensing chamber |
US11/833,471 Abandoned US20080021412A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage and Seal For Ophthalmic Medical Device |
US11/833,668 Expired - Fee Related US7887517B2 (en) | 2006-05-17 | 2007-08-03 | Drug casting |
US11/833,518 Abandoned US20080021419A1 (en) | 2006-05-17 | 2007-08-03 | Plunger Linkage Method For Ophthalmic Medical Device |
US12/109,079 Abandoned US20080197035A1 (en) | 2006-05-17 | 2008-04-24 | Sharps Container System for Two Piece Injection Device |
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-
2006
- 2006-05-17 US US11/435,906 patent/US20070270750A1/en not_active Abandoned
-
2007
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- 2007-05-15 CA CA002588519A patent/CA2588519A1/en not_active Abandoned
- 2007-05-16 TW TW096117365A patent/TW200744558A/en unknown
- 2007-05-16 BR BRPI0702340-5A patent/BRPI0702340A/en not_active IP Right Cessation
- 2007-05-16 MX MX2007005846A patent/MX2007005846A/en not_active Application Discontinuation
- 2007-05-17 IL IL183295A patent/IL183295A0/en unknown
- 2007-05-17 AU AU2007202216A patent/AU2007202216A1/en not_active Abandoned
- 2007-05-17 CN CNA200710104927XA patent/CN101073682A/en active Pending
- 2007-05-17 AR ARP070102129A patent/AR061002A1/en unknown
- 2007-05-17 KR KR1020070048065A patent/KR20070111394A/en not_active Application Discontinuation
- 2007-05-17 JP JP2007131544A patent/JP2007307376A/en active Pending
- 2007-06-14 US US11/762,844 patent/US7762981B2/en not_active Expired - Fee Related
- 2007-07-13 US US11/777,408 patent/US8821440B2/en not_active Expired - Fee Related
- 2007-08-03 US US11/833,471 patent/US20080021412A1/en not_active Abandoned
- 2007-08-03 US US11/833,668 patent/US7887517B2/en not_active Expired - Fee Related
- 2007-08-03 US US11/833,518 patent/US20080021419A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
---|---|
AU2007202216A1 (en) | 2007-12-06 |
MX2007005846A (en) | 2008-12-01 |
US20080015545A1 (en) | 2008-01-17 |
US7887517B2 (en) | 2011-02-15 |
TW200744558A (en) | 2007-12-16 |
CN101073682A (en) | 2007-11-21 |
CA2588519A1 (en) | 2007-11-17 |
EP1857130A1 (en) | 2007-11-21 |
IL183295A0 (en) | 2007-12-03 |
US7762981B2 (en) | 2010-07-27 |
AR061002A1 (en) | 2008-07-30 |
US20080021413A1 (en) | 2008-01-24 |
US8821440B2 (en) | 2014-09-02 |
US20080021419A1 (en) | 2008-01-24 |
US20080197035A1 (en) | 2008-08-21 |
JP2007307376A (en) | 2007-11-29 |
BRPI0702340A (en) | 2008-01-15 |
US20080021412A1 (en) | 2008-01-24 |
KR20070111394A (en) | 2007-11-21 |
US20080097311A1 (en) | 2008-04-24 |
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