US20070010811A1 - energy delivery device for treating tissue - Google Patents
energy delivery device for treating tissue Download PDFInfo
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- US20070010811A1 US20070010811A1 US11/531,081 US53108106A US2007010811A1 US 20070010811 A1 US20070010811 A1 US 20070010811A1 US 53108106 A US53108106 A US 53108106A US 2007010811 A1 US2007010811 A1 US 2007010811A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1402—Probes for open surgery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/148—Probes or electrodes therefor having a short, rigid shaft for accessing the inner body transcutaneously, e.g. for neurosurgery or arthroscopy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
- A61N1/403—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00702—Power or energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00779—Power or energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1495—Electrodes being detachable from a support structure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
- A61B2090/065—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension for measuring contact or contact pressure
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Abstract
Description
- This application is a continuation of U.S. application Ser. No. 10/072,610, which is a continuation-in-part of U.S. application Ser. No. 09/522,275, filed Mar. 9, 2000, now U.S. Pat. No. 6,413,255, which claims the benefit of U.S. application Ser. No. 60/123,440, filed Mar. 9, 1999. The disclosure of each of these applications is hereby incorporated by reference herein in its entirety.
- This invention relates generally to an electrode delivery device for treating tissue for treating skin and underlying tissues.
- The human skin is composed of two elements: the epidermis and the underlying dermis. The epidermis with the stratum corneum serves as a biological barrier to the environment. In the basilar layer of the epidermis, pigment-forming cells called melanocytes are present. They are the main determinants of skin color.
- The underlying dermis provides the main structural support of the skin. It is composed mainly of an extra-cellular protein called collagen. Collagen is produced by fibroblasts and synthesized as a triple helix with three polypeptide chains that are connected with heat labile and heat stable chemical bonds. When collagen-containing tissue is heated, alterations in the physical properties of this protein matrix occur at a characteristic temperature. The structural transition of collagen contraction occurs at a specific “shrinkage” temperature. The shrinkage and remodeling of the collagen matrix with heat is the basis for the technology.
- Collagen crosslinks are either intramolecular (covalent or hydrogen bond) or intermolecular (covalent or ionic bonds). The thermal cleavage of intramolecular hydrogen crosslinks is a scalar process that is created by the balance between cleavage events and relaxation events (reforming of hydrogen bonds). No external force is required for this process to occur. As a result, intermolecular stress is created by the thermal cleavage of intramolecular hydrogen bonds. Essentially, the contraction of the tertiary structure of the molecule creates the initial intermolecular vector of contraction.
- Collagen fibrils in a matrix exhibit a variety of spatial orientations. The matrix is lengthened if the sum of all vectors acts to distract the fibril. Contraction of the matrix is facilitated if the sum of all extrinsic vectors acts to shorten the fibril. Thermal disruption of intramolecular hydrogen bonds and mechanical cleavage of intermolecular crosslinks is also affected by relaxation events that restore preexisting configurations. However, a permanent change of molecular length will occur if crosslinks are reformed after lengthening or contraction of the collagen fibril. The continuous application of an external mechanical force will increase the probability of crosslinks forming after lengthening or contraction of the fibril.
- Hydrogen bond cleavage is a quantum mechanical event that requires a threshold of energy. The amount of (intramolecular) hydrogen bond cleavage required corresponds to the combined ionic and covalent intermolecular bond strengths within the collagen fibril. Until this threshold is reached, little or no change in the quaternary structure of the collagen fibril will occur. When the intermolecular stress is adequate, cleavage of the ionic and covalent bonds will occur. Typically, the intermolecular cleavage of ionic and covalent bonds will occur with a ratcheting effect from the realignment of polar and nonpolar regions in the lengthened or contracted fibril.
- Cleavage of collagen bonds also occurs at lower temperatures but at a lower rate. Low-level thermal cleavage is frequently associated with relaxation phenomena in which bonds are reformed without a net change in molecular length. An external force that mechanically cleaves the fibril will reduce the probability of relaxation phenomena and provides a means to lengthen or contract the collagen matrix at lower temperatures while reducing the potential of surface ablation.
- Soft tissue remodeling is a biophysical phenomenon that occurs at cellular and molecular levels. Molecular contraction or partial denaturization of collagen involves the application of an energy source, which destabilizes the longitudinal axis of the molecule by cleaving the heat labile bonds of the triple helix. As a result, stress is created to break the intermolecular bonds of the matrix. This is essentially an immediate extra-cellular process, whereas cellular contraction requires a lag period for the migration and multiplication of fibroblasts into the wound as provided by the wound healing sequence. In higher developed animal species, the wound healing response to injury involves an initial inflammatory process that subsequently leads to the deposition of scar tissue.
- The initial inflammatory response consists of the infiltration by white blood cells or leukocytes that dispose of cellular debris. Seventy-two hours later, proliferation of fibroblasts at the injured site occurs. These cells differentiate into contractile myofibroblasts, which are the source of cellular soft tissue contraction. Following cellular contraction, collagen is laid down as a static supporting matrix in the tightened soft tissue structure. The deposition and subsequent remodeling of this nascent scar matrix provides the means to alter the consistency and geometry of soft tissue for aesthetic purposes.
- In light of the preceding discussion, there are a number of dermatological procedures that lend themselves to treatments which deliver thermal energy to the skin and underlying tissue to cause a contraction of collagen, and/or initiate a would healing response. Such procedures include skin remodeling/resurfacing, wrinkle removal, and treatment of the sebaceous glands, hair follicles adipose tissue and spider veins. Currently available technologies that deliver thermal energy to the skin and underlying tissue include Radio Frequency (RF), optical (laser) and other forms of electromagnetic energy. However, these technologies have a number of technical limitations and clinical issues which limit the effectiveness of the treatment and/or preclude treatment altogether. These issues include the following: i) achieving a uniform thermal effect across a large area of tissue, ii) controlling the depth of the thermal effect to target selected tissue and prevent unwanted thermal damage to both target and non-target tissue, iii) reducing adverse tissue effects such as burns, redness blistering, iv) replacing the practice of delivery energy/treatment in a patchwork fashion with a more continuous delivery of treatment (e.g. by a sliding or painting motion), v) improving access to difficult-to-reach areas of the skin surface and vi) reducing procedure time and number of patient visits required to complete treatment. As will be discussed herein the current invention provides an apparatus for solving these and other limitations.
- One of the key shortcomings of currently available RF technology for treating the skin is the edge effect phenomenon. In general, when RF energy is being applied or delivered to tissue through an electrode which is in contact with that tissue, the current patterns concentrate around the edges of the electrode, sharp edges in particular. This effect is generally known as the edge effect. In the case of a circular disc electrode, the effect manifests as a higher current density around the perimeter of that circular disc and a relatively low current density in the center. For a square- shaped electrode there is typically a high current density around the entire perimeter, and an even higher current density at the corners where there is a sharp edge.
- Edge effects cause problems in treating the skin for several reasons. First, they result in a non-uniform thermal effect over the electrode surface. In various treatments of the skin, it is important to have a uniform thermal effect over a relatively large surface area, particularly for dermatologic treatments. Large in this case being on the order of several square millimeters or even several square centimeters. In electrosurgical applications for cutting tissue, there typically is a point type applicator designed with the goal of getting a hot spot at that point for cutting or even coagulating tissue. However, this point design is undesirable for creating a reasonably gentle thermal effect over a large surface area. What is needed is an electrode design to deliver uniform thermal energy to skin and underlying tissue without hot spots.
- A uniform thermal effect is particularly important when cooling is combined with heating in skin/tissue treatment procedure. As is discussed below, a non-uniform thermal pattern makes cooling of the skin difficult and hence the resulting treatment process as well. When heating the skin with RF energy, the tissue at the electrode surface tends to be warmest with a decrease in temperature moving deeper into the tissue. One approach to overcome this thermal gradient and create a thermal effect at a set distance away from the electrode is to cool the layers of skin that are in contact with the electrode. However, cooling of the skin is made difficult if there is a non-uniform heating pattern. If the skin is sufficiently cooled such that there are no burns at the corners of a square or rectangular electrode, or at the perimeter of a circular disc electrode, then there will probably be overcooling in the center and there won't be any significant thermal effect (i.e. tissue heating) under the center of the electrode. Contrarily, if the cooling effect is decreased to the point where there is a good thermal effect in the center of the electrode, then there probably will not be sufficient cooling to protect tissue in contact with the edges of the electrode. As a result of these limitations, in the typical application of a standard electrode there is usually an area of non-uniform treatment and/or burns on the skin surface. So uniformity of the heating pattern is very important. It is particularly important in applications treating skin where collagen-containing layers are heated to produce a collagen contraction response for tightening of the skin. For this and related applications, if the collagen contraction and resulting skin tightening effect are non-uniform, then a medically undesirable result may occur.
- There is a need for an improved RF handpiece for cosmetic applications.
- Accordingly, an object of the present invention is to provide an RF handpiece which provides a substantially uniform delivery of energy to a target tissue site.
- Another object of the present invention is to provide an RF handpiece which includes at least one RF electrode that is capacitively coupled to a skin surface when at least a portion of the RF electrode is in contact with the skin surface.
- Yet another object of the present invention is to provide an RF handpiece that provides a uniform thermal effect in tissue at a selected depth, while preventing or minimizing thermal damage to a skin surface and other non-target tissue.
- A further object of the present invention is to provide an RF handpiece configured to reduce or eliminate the edge effects and hot spots of RF electrodes applied to skin surfaces.
- Another object of the present invention is to provide an RF handpiece configured to provide an atomizing delivery of a cooling fluidic medium to the RF electrode.
- Still another object of the present invention is to provide an RF handpiece configured to evaporatively cool the back surface of the RF electrode, and conductively cool a skin surface adjacent to a front surface of the RF electrode.
- A further object of the present invention is to provide an RF handpiece configured to controllably deliver a cooling fluidic medium to the back surface of the RF electrode at substantially any orientation of the front surface of the RF electrode relative to a direction of gravity.
- Yet another object of the present invention is to provide an RF handpiece that includes an RF electrode with both conductive and dielectric portions.
- Another object of the present invention is to provide an RF handpiece that includes a force sensor that zeros out gravity effects created by the weight of the electrode assembly of the RF handpiece in any orientation of the front surface of the RF electrode relative to a direction of gravity.
- These and other objects of the present invention are achieved in a handpiece that has a handpiece assembly. The handpiece assembly includes a handpiece housing and a cooling fluidic medium valve member. An electrode assembly is coupled to the handpiece housing. The electrode assembly has a least one RF electrode that is capacitively coupled to a skin surface when at least a portion of the RF electrode is in contact with the skin surface.
- In another embodiment of the present invention a handpiece, a handpiece assembly includes a handpiece housing and a cooling fluidic medium valve member with an inlet and an outlet. An electrode assembly is removeably coupled to the handpiece housing. The electrode assembly has a least one RF electrode with a front surface and a back surface. The RF electrode is capacitively coupled to a skin surface when at least a portion of the RF electrode is in contact with the skin surface.
- In another embodiment of the present invention, a handpiece includes a handpiece assembly with a handpiece housing. An insert is at least partially positionable in the handpiece housing. An RF electrode is coupled to the insert. The RF electrode has a back surface that faces the handpiece housing and an opposing front surface. A cooling fluidic medium dispensing assembly is coupled to the handpiece housing and the insert.
- In another embodiment of the present invention, a handpiece includes a handpiece assembly with a handpiece housing. An insert is detachably coupled to the handpiece housing. The insert includes an RF electrode with a conductive portion and a dielectric.
- In another embodiment of the present invention, a handpiece includes a handpiece assembly with a handpiece housing. An insert is detachably coupled to the handpiece housing. An RF electrode is positioned in the insert. The RF electrode includes a flex circuit.
- In another embodiment of the present invention, a handpiece includes a handpiece assembly with a handpiece housing. An insert is detachably coupled to the handpiece housing. The insert includes a flex circuit and an RF electrode that with a conductive portion and a dielectric.
- In another embodiment, an electrode assembly is adapted to be coupled with a handpiece and powered to treat skin and underlying tissues. A sensor is coupled to the energy delivery device. The sensor may comprise, for example, a force sensor or a thermal sensor.
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FIG. 1 is a cross-sectional view of one embodiment of the handpiece of the present invention. -
FIG. 2 is an exploded view of theFIG. 1 insert assembly. -
FIG. 3 is a close-up view of one embodiment of an RF electrode of the present invention. -
FIG. 4 is another cross-sectional view of a portion of the handpiece housing fromFIG. 1 . -
FIG. 5 is a cross-sectional view of the insert fromFIG. 1 . - Referring now to
FIG. 1 , one embodiment of the present invention is ahandpiece 10 with a handpiece assembly 12. Handpiece assembly 12 includes ahandpiece housing 14 and a cooling fluidicmedium valve member 16. Anelectrode assembly 18 is coupled to handpiecehousing 14.Electrode assembly 18 has a least oneRF electrode 20 that is capacitively coupled to a skin surface when at least a portion ofRF electrode 20 is in contact with the skin surface. Without limiting the scope of the present invention,RF electrode 20 can have a thickness in the range of 0.010 to 1.0 mm. -
Handpiece 10 provides a more uniform thermal effect in tissue at a selected depth, while preventing or minimizing thermal damage to the skin surface and other non-target tissue.Handpiece 10 is coupled to an RF generator.RF electrode 20 can be operated either in mono-polar or bi-polar modes.Handpiece 10 is configured to reduce, or preferably eliminate edge effects and hot spots. The result is an improved aesthetic result/clinical outcome with an elimination/reduction in adverse effects and healing time. - A
fluid delivery member 22 is coupled to cooling fluidicmedium valve member 16.Fluid delivery member 22 and cooling fluidicmedium valve member 16 collectively form a cooling fluidic medium dispensing assembly.Fluid delivery member 16 is configured to provide an atomizing delivery of a cooling fluidic medium toRF electrode 20. The atomizing delivery is a mist or fine spray. A phase transition, from liquid to gas, of the cooling fluidic medium occurs when it hits the surface ofRF electrode 20. The transition from liquid to gas creates the cooling. If the transition before the cooling fluidic medium hitsRF electrode 20 the cooling ofRF electrode 20 will not be as effective. - In one embodiment, the cooling fluidic medium is a cryogenic spray, commercially available from Honeywell, Morristown, N.J. A specific example of a suitable cryogenic spray is R134A2, available from Refron, Inc., 38-18 33rd St., Long Island City, N.Y. 11101. The use of a cryogenic cooling fluidic medium provides the capability to use a number of different types of algorithms for skin treatment. For example, the cryogenic cooling fluidic medium can be applied milliseconds before and after the delivery of RF energy to the desired tissue. This is achieved with the use of cooling fluidic
medium valve member 16 coupled to a cryogen supply, including but not limited to a compressed gas canister. In various embodiments, cooling fluidicmedium valve member 16 can be coupled to a computer control system and/or manually controlled by the physician by means of a foot switch or similar device. - A key advantage of providing a spray, or atomization, of cryogenic cooling fluidic medium is the availability to implement rapid on and off control. Cryogenic cooling fluidic medium allows more precise temporal control of the cooling process. This is because cooling only occurs when the refrigerant is sprayed and is in an evaporative state, the latter being a very fast short-lived event. Thus, cooling ceases rapidly after the cryogenic cooling fluidic medium is stopped. The overall effect is to confer very precise time on-off control of cryogenic cooling fluidic medium.
- Referring now to
FIG. 2 ,fluid delivery member 22 can be positioned inhandpiece housing 14 orelectrode assembly 18.Fluid delivery member 22 is configured to controllably deliver a cooling fluidic medium to aback surface 24 ofRF electrode 20 and maintain backsurface 24 at a desired temperature. The cooling fluidic medium evaporatively coolsRF electrode 20 and maintains a substantially uniform temperature offront surface 26 ofRF electrode 20.Front surface 26 can be sufficiently flexible and conformable to the skin, but still have sufficient strength and/or structure to provide good thermal coupling when pressed against the skin surface. -
RF electrode 20 then conductively cools a skin surface that is adjacent to afront surface 26 ofRF electrode 20. Suitable fluidic media include a variety of refrigerants such as R134A and freon.Fluid delivery member 22 is configured to controllably deliver the cooling fluidic medium to backsurface 24 at substantially any orientation offront surface 26 relative to a direction of gravity. A geometry and positioning offluid delivery member 22 are selected to provide a substantially uniform distribution of cooling fluidic medium onback surface 24. The delivery of the cooling fluidic medium can be by spray of droplets or fine mist, flooding backsurface 24, and the like. Cooling occurs at the interface of the cooling fluidic medium with atmosphere, which is where evaporation occurs. If there is a thick layer of fluid onback surface 24 the heat removed from the treated skin will need to pass through the thick layer of cooling fluidic medium, increasing thermal resistance. To maximize cooling rates, it is desirable to apply a very thin layer of cooling fluidic medium. IfRF electrode 20 is not horizontal, and if there is a thick layer of cooling fluidic medium, or if there are large drops of cooling fluidic medium onback surface 24, the cooling fluidic medium can run down the surface ofRF electrode 20 and pool at one edge or corner, causing uneven cooling. Therefore, it is desirable to apply a thin layer of cooling fluidic medium with a fine spray. - In various embodiments,
RF electrode 20, as illustrated inFIG. 3 , has aconductive portion 28 and adielectric portion 30.Conductive portion 28 can be a metal including but not limited to copper, gold, silver, aluminum and the like.Dielectric portion 30 can be made of a variety of different materials including but not limited to polyimide, and the like. Other dielectric materials include but are not limited to silicon, sapphire, diamond, zirconium-toughened alumina (ZTA), alumina and the like.Dielectric portion 30 can be positioned around at least a portion, or the entirety of a periphery ofconductive portion 28. Suitable materials for adielectric portion 30 include, but are not limited to, Teflon® and the like, silicon nitride, polysilanes, polysilazanes, polyimides, Kapton and other polymers, antenna dielectrics and other dielectric materials well known in the art. In another embodiment,RF electrode 20 is made of a composite material, including but not limited to gold-plated copper, copper-polyimide, silicon/silicon-nitride and the like. -
Dielectric portion 30 creates an increased impedance to the flow of electrical current throughRF electrode 20. This increased impedance causes current to travel a path straight down throughconductive portion 28 to the skin surface. Electric field edge effects, caused by a concentration of current flowing out of the edges ofRF electrode 20, are reduced. -
Dielectric portion 30 produces a more uniform impedance throughRF electrode 20 and causes a more uniform current to flow throughconductive portion 28. The resulting effect minimizes or even eliminates, edge effects around the edges ofRF electrode 20. - In one embodiment,
conductive portion 28 adheres todielectric portion 30 which can be substrate with a thickness, by way of example and without limitation, of about 0.001″. This embodiment is similar to a standard flex circuit board material commercially available in the electronics industry. In this embodiment,dielectric portion 30 is in contact with the tissue, the skin, andconductive portion 28 is separated from the skin. The thickness of thedielectric portion 30 can be decreased by growingconductive portion 28 ondielectric portion 30 using a variety of techniques, including but not limited to, sputtering, electro deposition, chemical vapor deposition, plasma deposition and other deposition techniques known in the art. Additionally, these same processes can be used to depositdielectric portion 30 ontoconductive portion 28. In one embodimentdielectric portion 30 is an oxide layer which can be grown onconductive portion 28. An oxide layer has a low thermal resistance and improves the cooling efficiency of the skin compared with many other dielectrics such as polymers. -
Fluid delivery member 22 has aninlet 32 and anoutlet 34.Outlet 34 can have a smaller cross-sectional area than a cross-sectional area ofinlet 32. In one embodiment,fluid delivery member 22 is anozzle 36. - Cooling fluidic
medium valve member 16 can be configured to provide a pulsed delivery of the cooling fluidic medium. Pulsing the delivery of cooling fluidic medium is a simple way to control the rate of cooling fluidic medium application. In one embodiment, cooling fluidicmedium valve member 16 is a solenoid valve. An example of a suitable solenoid valve is a solenoid pinch valve manufactured by the N-Research Corporation, West Caldwell, N.J. If the fluid is pressurized, then opening of the valve results in fluid flow. If the fluid is maintained at a constant pressure, then the flow rate is constant and a simple open/close solenoid valve can be used, the effective flow rate being determined by the pulse duty cycle. A higher duty cycle, close to 100% increases cooling, while a lower duty cycle, closer to 0%, reduces cooling. The duty cycle can be achieved by turning on the valve for a short duration of time at a set frequency. The duration of the open time can be 1 to 50 milliseconds or longer. The frequency of pulsing can be 1 to 50 Hz or faster. - Alternatively, cooling fluidic medium flow rate can be controlled by a metering valve or controllable-rate pump such as a peristaltic pump. One advantage of pulsing is that it is easy to control using simple electronics and control algorithms.
-
Electrode assembly 18 is sufficiently sealed so that the cooling fluidic medium does not leak fromback surface 24 onto a skin surface in contact with a front surface ofRF electrode 20. This helps provide an even energy delivery through the skin surface. In one embodiment,electrode assembly 18, and more specificallyRF electrode 20, has a geometry that creates a reservoir at backsurface 24 to hold and gather cooling fluidic medium that has collected at backsurface 24. Back surface 24 can be formed with “hospital corners” to create this reservoir. Optionally,electrode assembly 18 includes avent 38 that permits vaporized cooling fluidic medium to escape fromelectrode assembly 18. This reduces the chance of cooling fluidic medium collecting at backsurface 24. This can occur when cooling fluidic medium is delivered to backsurface 24 in vapor form and then, following cooling ofback surface 24, the vapor condenses to a liquid. -
Vent 38 prevents pressure from building up inelectrode assembly 18.Vent 38 can be a pressure relief valve that is vented to the atmosphere or a vent line. When the cooling fluidic medium comes into contact withRF electrode 20 and evaporates, the resulting gas pressurizes the inside ofelectrode assembly 18. This can causeRF electrode 20 to partially inflate and bow out fromfront surface 26. Theinflated RF electrode 20 can enhance the thermal contact with the skin and also result in some degree of conformance ofRF electrode 20 to the skin surface. An electronic controller can be provided. The electronic controller sends a signal to openvent 38 when a programmed pressure has been reached. - Various leads 40 are coupled to
RF electrode 20. One or morethermal sensors 42 are coupled to RF electrode. Suitablethermal sensors 42 include but are not limited to thermocouples, thermistors, infrared photo-emitters and a thermally sensitive diode. In one embodiment, athermal sensor 42 is positioned at each comer ofRF electrode 20. A sufficient number ofthermal sensors 42 are provided in order to acquire sufficient thermal data of the skin surface.Thermal sensors 42 are electrically isolated fromRF electrode 20. -
Thermal sensors 42 measure temperature and can provide feedback for monitoring temperature ofRF electrode 20 and/or the tissue during treatment.Thermal sensors 42 can be thermistors, thermocouples, thermally sensitive diodes, capacitors, inductors or other devices for measuring temperature. Preferably,thermal sensors 42 provide electronic feedback to a microprocessor of the RF generator coupled toRF electrode 20 in order to facilitate control of the treatment. - The measurements from
thermal sensors 42 can be used to help control the rate of application of cooling fluidic medium. For example, the cooling control algorithm can be used to apply cooling fluidic medium toRF electrode 20 at a high flow rate until the temperature fell below a target temperature, and then slow down or stop. A PID, or proportional-integral-differential, algorithm can be used to precisely controlRF electrode 20 temperature to a predetermined value. -
Thermal sensors 42 can be positioned placed onback surface 24 ofRF electrode 20 away from the tissue. This configuration is preferable ideal for controlling the temperature of theRF electrode 20. Alternatively,thermal sensors 42 can be positioned onfront surface 26 ofRF electrode 10 in direct contact with the tissue. This embodiment can be more suitable for monitoring tissue temperature. Algorithms are utilized withthermal sensors 42 to calculate a temperature profile of the treated tissue.Thermal sensors 42 can be used to develop a temperature profile of the skin which is then used for process control purposes to assure that the proper amounts of heating and cooling are delivered to achieve a desired elevated deep tissue temperature while maintaining skin tissue layers below a threshold temperature and avoid thermal injury. The physician can use the measured temperature profile to assure that he stays within the boundary of an ideal/average profile for a given type of treatment.Thermal sensors 42 can be used for additional purposes. When the temperature ofthermal sensors 42 is monitored it is possible to detect whenRF electrode 20 is in contact with the skin surface. This can be achieved by detecting a direct change in temperature when skin contact is made or examining the rate of change of temperature which is affected by contact with the skin. Similarly, if there is more than onethermal sensor 42, thethermal sensors 42 can be used to detect whether a portion ofRF electrode 20 is lifted or out of contact with skin. This can be important because the current density (amperes per unit area) delivered to the skin can vary if the contact area changes. In particular, if part of the surface ofRF electrode 20 is not in contact with the skin, the resulting current density is higher than expected. - Referring now to
FIG. 4 , aforce sensor 44 is also coupled toelectrode assembly 18.Force sensor 44 detects an amount of force applied byelectrode assembly 18, via the physician, against an applied skin surface.Force sensor 44 zeros out gravity effects of the weight ofelectrode assembly 18 in any orientation offront surface 26 ofRF electrode 20 relative to a direction of gravity. Additionally,force sensor 44 provides an indication whenRF electrode 20 is in contact with a skin surface.Force sensor 44 also provides a signal indicating that a force applied byRF electrode 20 to a contacted skin surface is, (i) below a minimum threshold or (ii) above a maximum threshold. - An
activation button 46 is used in conjunction with the force sensor. Just prior to activatingRF electrode 20, the physician holdshandpiece 10 in position just off the surface of the skin. The orientation ofhandpiece 10 can be any angle relative to the angle of gravity. Toarm handpiece 10, the physician can pressactivation button 46 which tares forcesensor 44, by setting it to read zero. This cancels the force due to gravity in that particular treatment orientation. This method allows consistent force application ofRF electrode 20 to the skin surface regardless of the angle ofhandpiece 10 relative to the direction of gravity. -
RF electrode 20 can be a flex circuit, which can include trace components. Additionally,thermal sensor 42 andforce sensor 44 can be part of the flex circuit. Further, the flex circuit can include a dielectric that forms a part ofRF electrode 20. -
Electrode assembly 18 can be moveable positioned within handpiece housing 12. In one embodiment,electrode assembly 18 is slideably moveable along a longitudinal axis of handpiece housing 12.Electrode assembly 18 can be rotatably mounted in handpiece housing 12. Additionally,RF electrode 20 can be rotatably positioned inelectrode assembly 18.Electrode assembly 18 can be removably coupled to handpiece housing 12 as a disposable ornon-disposable insert 52, seeFIG. 5 . For purposes of this disclosure,electrode assembly 18 is the same asinsert 52. Once movably mounted to handpiece housing 12, insert 52 can be coupled to handpiece housing 12 viaforce sensor 44.Force sensor 44 can be of the type that is capable of measuring both compressive and tensile forces. In other embodiments,force sensor 44 only measures compressive forces, or only measures tensile forces. -
Insert 52 can be spring-loaded with aspring 48. In one embodiment,spring 48biases RF electrode 20 in a direction toward handpiece housing 12. This pre-loadsforce sensor 44 and keeps insert 52 pressed againstforce sensor 44. The pre-load force is tared whenactivation button 46 is pressed just prior to application ofRF electrode 20 to the skin surface. - A
shroud 50 is optionally coupled tohandpiece 10.Shroud 50 serves to keep the user from touchinginsert 52 during use which can cause erroneous force readings. - A
non-volatile memory 54 can be included withinsert 52. Additionally, non-volatile memory can be included with handpiece housing 12.Non-volatile memory 54 can be an EPROM and the like. Additionally, a secondnon-volatile memory 56 can be included in handpiece housing 12 for purposes of storinghandpiece 10 information such as but not limited to, handpiece model number or version, handpiece software version, number of RF applications that handpiece 10 has delivered, expiration date and manufacture date. Handpiece housing 12 can also contain amicroprocessor 58 for purposes of acquiring and analyzing data from various sensors on handpiece housing 12 or insert 52 including but not limited tothermal sensors 42,force sensors 44, fluid pressure gauges, switches, buttons and the like.Microprocessor 58 can also control components onhandpiece 10 including but not limited to lights, LEDs, valves, pumps or other electronic components.Microprocessor 58 can also communicate data to a microprocessor of the RF generator. -
Non-volatile memory 54 can store a variety of data that can facilitate control and operation ofhandpiece 10 and its associated system including but not limited to, (i) controlling the amount of current delivered byRF electrode 20, (ii) controlling the duty cycle of thefluid delivery member 22, (iii) controlling the energy delivery duration time of theRF electrode 20, (iv) controlling the temperature ofRF electrode 20 relative to a target temperature, (v) providing a maximum number of firings ofRF electrode 20, (vi) providing a maximum allowed voltage that is deliverable byRF electrode 20, (vii) providing a history ofRF electrode 20 use, (viii) providing a controllable duty cycle tofluid delivery member 22 for the delivery of the cooling fluidic medium to backsurface 24 ofRF electrode 20, (ix) providing a controllable delivery rate of cooling fluidic medium delivered fromfluid delivery member 22 to backsurface 24, and the like. -
Handpiece 10 can be used to deliver thermal energy to modify tissue including, but not limited to, collagen containing tissue, in the epidermal, dermal and subcutaneous tissue layers, including adipose tissue. The modification of the tissue includes modifying a physical feature of the tissue, a structure of the tissue or a physical property of the tissue. The modification can be achieved by delivering sufficient energy to cause collagen shrinkage, and/or a wound healing response including the deposition of new or nascent collagen. -
Handpiece 10 can be utilized for performing a number of treatments of the skin and underlying tissue including but not limited to, (i) dermal remodeling and tightening, (ii) wrinkle reduction, (iii) elastosis reduction, (iv) sebaceous gland removal/deactivation, (v) hair follicle removal, (vi) adipose tissue remodeling/removal, (vii) spider vein removal, and the like. - In various embodiments,
handpiece 10 can be utilized in a variety of treatment processes, including but not limited to, (i) pre-cooling, before the delivery of energy to the tissue has begun, (ii) an on phase or energy delivery phase in conjunction with cooling and (iii) post cooling after the delivery of energy to tissue has stopped. -
Handpiece 10 can be used to pre-cool the surface layers of the target tissue so that whenRF electrode 20 is in contact with the tissue, or prior to turning on the RF energy source, the superficial layers of the target tissue are already cooled. When RF energy source is turned on or delivery of RF to the tissue otherwise begins, resulting in heating of the tissues, the tissue that has been cooled is protected from thermal effects including thermal damage. The tissue that has not been cooled will warm up to therapeutic temperatures resulting in the desired therapeutic effect. - Pre-cooling gives time for the thermal effects of cooling to propagate down into the tissue. More specifically, pre-cooling allows the achievement of a desired tissue depth thermal profile, with a minimum desired temperature being achieved at a selectable depth. The amount or duration of pre-cooling can be used to select the depth of the protected zone of untreated tissue. Longer durations of pre-cooling produce a deeper protected zone and hence a deeper level in tissue for the start of the treatment zone. The opposite is true for shorter periods of pre-cooling. The temperature of
front surface 26 ofRF electrode 20 also affects the temperature profile. The colder the temperature offront surface 26, the faster and deeper the cooling, and vice verse. - Post-cooling can be important because it prevents and/or reduces heat delivered to the deeper layers from conducting upward and heating the more superficial layers possibly to therapeutic or damaging temperature range even though external energy delivery to the tissue has ceased. In order to prevent this and related thermal phenomena, it can be desirable to maintain cooling of the treatment surface for a period of time after application of the RF energy has ceased. In various embodiments, varying amounts of post cooling can be combined with real-time cooling and/or pre-cooling.
- In various embodiments,
handpiece 10 can be used in a varied number of pulse on-off type cooling sequences and algorithms may be employed. In one embodiment, the treatment algorithm provides for pre-cooling of the tissue by starting a spray of cryogenic cooling fluidic medium, followed by a short pulse of RF energy into the tissue. In this embodiment, the spray of cryogenic cooling fluidic medium continues while the RF energy is delivered, and is stopping shortly thereafter, e.g. on the order of milliseconds. This or another treatment sequence can be repeated again. Thus in various embodiments, the treatment sequence can include a pulsed sequence of cooling on, heat, cooling off, cooling on, heat, cool off, and with cooling and heating durations on orders of tens of milliseconds. In these embodiments, every time the surface of the tissue of the skin is cooled, heat is removed from the skin surface. Cryogenic cooling fluidic medium spray duration, and intervals between sprays, can be in the tens of milliseconds ranges, which allows surface cooling while still delivering the desired thermal effect into the deeper target tissue. - In various embodiments, the target tissue zone for therapy, also called therapeutic zone or thermal effect zone, can be at a tissue depth from approximately 100 μm beneath the surface of the skin down to as deep as 10 millimeters, depending upon the type of treatment. For treatments involving collagen contraction, it can be desirable to cool both the epidermis and the superficial layers of the dermis of the skin that lies beneath the epidermis, to a cooled depth range between 100 μm two millimeters. Different treatment algorithms can incorporate different amounts of pre-cooling, heating and post cooling phases in order to produce a desired tissue effect at a desired depth.
- Various duty cycles, on and off times, of cooling and heating are utilized depending on the type of treatment. The cooling and heating duty cycles can be controlled and dynamically varied by an electronic control system known in the art. Specifically the control system can be used to control cooling fluidic
medium valve member 16 and the RF power source. - The foregoing description of a preferred embodiment of the invention has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations will be apparent to practitioners skilled in this art. It is intended that the scope of the invention be defined by the following claims and their equivalents.
Claims (13)
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US14/074,927 US9636175B2 (en) | 1999-03-09 | 2013-11-08 | Apparatus for transcutaneously treating tissue |
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Cited By (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050222565A1 (en) * | 2004-04-01 | 2005-10-06 | Dieter Manstein | Method and apparatus for dermatological treatment and tissue reshaping |
US20080009923A1 (en) * | 2006-06-14 | 2008-01-10 | Paithankar Dilip Y | Treatment of Skin by Spatial Modulation of Thermal Heating |
US20080077201A1 (en) * | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
US20080269734A1 (en) * | 2007-04-26 | 2008-10-30 | Agustina Vila Echague | Optical Array for Treating Biological Tissue |
US20080306418A1 (en) * | 2007-06-05 | 2008-12-11 | Reliant Technologies, Inc. | Method for Reducing Pain of Dermatological Treatments |
US20090043301A1 (en) * | 2007-08-09 | 2009-02-12 | Asthmatx, Inc. | Monopolar energy delivery devices and methods for controlling current density in tissue |
US20090281540A1 (en) * | 2008-05-06 | 2009-11-12 | Blomgren Richard D | Apparatus, Systems and Methods for Treating a Human Tissue Condition |
US20100179455A1 (en) * | 2009-01-12 | 2010-07-15 | Solta Medical, Inc. | Tissue treatment apparatus with functional mechanical stimulation and methods for reducing pain during tissue treatments |
US20100280582A1 (en) * | 2009-04-30 | 2010-11-04 | Zeltiq Aesthetics, Inc. | Device, system and method of removing heat from subcutaneous lipid-rich cells |
US20100298825A1 (en) * | 2009-05-08 | 2010-11-25 | Cellutions, Inc. | Treatment System With A Pulse Forming Network For Achieving Plasma In Tissue |
US20110202048A1 (en) * | 2010-02-12 | 2011-08-18 | Solta Medical, Inc. | Methods for pain reduction with functional thermal stimulation and tissue treatment systems |
US20110238051A1 (en) * | 2010-01-25 | 2011-09-29 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods |
US8073550B1 (en) | 1997-07-31 | 2011-12-06 | Miramar Labs, Inc. | Method and apparatus for treating subcutaneous histological features |
US8401668B2 (en) | 2007-04-19 | 2013-03-19 | Miramar Labs, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
US8406894B2 (en) | 2007-12-12 | 2013-03-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
US8788060B2 (en) | 2009-07-16 | 2014-07-22 | Solta Medical, Inc. | Tissue treatment systems with high powered functional electrical stimulation and methods for reducing pain during tissue treatments |
US8882758B2 (en) | 2009-01-09 | 2014-11-11 | Solta Medical, Inc. | Tissue treatment apparatus and systems with pain mitigation and methods for mitigating pain during tissue treatments |
WO2015160076A1 (en) * | 2014-04-17 | 2015-10-22 | 주식회사 제이에스온 | High-frequency thermotherapy device |
US9277958B2 (en) | 2012-02-22 | 2016-03-08 | Candela Corporation | Reduction of RF electrode edge effect |
US9375345B2 (en) | 2006-09-26 | 2016-06-28 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US9408745B2 (en) | 2007-08-21 | 2016-08-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
US9655770B2 (en) | 2007-07-13 | 2017-05-23 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
US9737434B2 (en) | 2008-12-17 | 2017-08-22 | Zeltiq Aestehtics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
US9861421B2 (en) | 2014-01-31 | 2018-01-09 | Zeltiq Aesthetics, Inc. | Compositions, treatment systems and methods for improved cooling of lipid-rich tissue |
US9889297B2 (en) | 2012-02-22 | 2018-02-13 | Candela Corporation | Reduction of RF electrode edge effect |
US10383787B2 (en) | 2007-05-18 | 2019-08-20 | Zeltiq Aesthetics, Inc. | Treatment apparatus for removing heat from subcutaneous lipid-rich cells and massaging tissue |
US10524956B2 (en) | 2016-01-07 | 2020-01-07 | Zeltiq Aesthetics, Inc. | Temperature-dependent adhesion between applicator and skin during cooling of tissue |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
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US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
US11395760B2 (en) | 2006-09-26 | 2022-07-26 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US11446175B2 (en) | 2018-07-31 | 2022-09-20 | Zeltiq Aesthetics, Inc. | Methods, devices, and systems for improving skin characteristics |
USD971415S1 (en) | 2019-12-30 | 2022-11-29 | Cynosure, Llc | Flexible applicator |
Families Citing this family (299)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7267675B2 (en) * | 1996-01-05 | 2007-09-11 | Thermage, Inc. | RF device with thermo-electric cooler |
US7473251B2 (en) * | 1996-01-05 | 2009-01-06 | Thermage, Inc. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US7229436B2 (en) | 1996-01-05 | 2007-06-12 | Thermage, Inc. | Method and kit for treatment of tissue |
US10285694B2 (en) | 2001-10-20 | 2019-05-14 | Covidien Lp | Surgical stapler with timer and feedback display |
US7464847B2 (en) | 2005-06-03 | 2008-12-16 | Tyco Healthcare Group Lp | Surgical stapler with timer and feedback display |
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US8361067B2 (en) | 2002-09-30 | 2013-01-29 | Relievant Medsystems, Inc. | Methods of therapeutically heating a vertebral body to treat back pain |
US7244257B2 (en) * | 2002-11-05 | 2007-07-17 | Sherwood Services Ag | Electrosurgical pencil having a single button variable control |
JP4469843B2 (en) | 2003-02-20 | 2010-06-02 | コヴィディエン アクチェンゲゼルシャフト | Motion detector for controlling electrosurgical output |
US11311291B2 (en) | 2003-10-17 | 2022-04-26 | Covidien Lp | Surgical adapter assemblies for use between surgical handle assembly and surgical end effectors |
US10022123B2 (en) | 2012-07-09 | 2018-07-17 | Covidien Lp | Surgical adapter assemblies for use between surgical handle assembly and surgical end effectors |
US10041822B2 (en) | 2007-10-05 | 2018-08-07 | Covidien Lp | Methods to shorten calibration times for powered devices |
US9055943B2 (en) | 2007-09-21 | 2015-06-16 | Covidien Lp | Hand held surgical handle assembly, surgical adapters for use between surgical handle assembly and surgical end effectors, and methods of use |
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US8968276B2 (en) | 2007-09-21 | 2015-03-03 | Covidien Lp | Hand held surgical handle assembly, surgical adapters for use between surgical handle assembly and surgical end effectors, and methods of use |
US7503917B2 (en) | 2003-11-20 | 2009-03-17 | Covidien Ag | Electrosurgical pencil with improved controls |
US7879033B2 (en) | 2003-11-20 | 2011-02-01 | Covidien Ag | Electrosurgical pencil with advanced ES controls |
US7156842B2 (en) | 2003-11-20 | 2007-01-02 | Sherwood Services Ag | Electrosurgical pencil with improved controls |
US7476242B2 (en) | 2004-01-30 | 2009-01-13 | Ams Research Corporation | Electrically heated/phase change probe temperature control |
US20060047281A1 (en) | 2004-09-01 | 2006-03-02 | Syneron Medical Ltd. | Method and system for invasive skin treatment |
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US7500974B2 (en) | 2005-06-28 | 2009-03-10 | Covidien Ag | Electrode with rotatably deployable sheath |
US7828794B2 (en) | 2005-08-25 | 2010-11-09 | Covidien Ag | Handheld electrosurgical apparatus for controlling operating room equipment |
US20070078502A1 (en) * | 2005-10-05 | 2007-04-05 | Thermage, Inc. | Method and apparatus for estimating a local impedance factor |
US7957815B2 (en) * | 2005-10-11 | 2011-06-07 | Thermage, Inc. | Electrode assembly and handpiece with adjustable system impedance, and methods of operating an energy-based medical system to treat tissue |
US8702691B2 (en) * | 2005-10-19 | 2014-04-22 | Thermage, Inc. | Treatment apparatus and methods for delivering energy at multiple selectable depths in tissue |
WO2007092610A2 (en) * | 2006-02-07 | 2007-08-16 | Tivamed, Inc. | Vaginal remodeling device and methods |
JP5055500B2 (en) * | 2006-04-04 | 2012-10-24 | 並木精密宝石株式会社 | Therapeutic antenna probe, method of use thereof, and electromagnetic therapeutic system |
US20070260240A1 (en) | 2006-05-05 | 2007-11-08 | Sherwood Services Ag | Soft tissue RF transection and resection device |
US8317782B1 (en) * | 2006-10-13 | 2012-11-27 | Ellman International, Inc. | Non-ablative radio-frequency treatment of skin tissue |
US8142426B2 (en) | 2006-10-16 | 2012-03-27 | Syneron Medical Ltd. | Methods and devices for treating tissue |
US8133216B2 (en) | 2006-10-16 | 2012-03-13 | Syneron Medical Ltd. | Methods and devices for treating tissue |
US8007493B2 (en) | 2006-10-16 | 2011-08-30 | Syneron Medical Ltd. | Methods and devices for treating tissue |
US8273080B2 (en) | 2006-10-16 | 2012-09-25 | Syneron Medical Ltd. | Methods and devices for treating tissue |
US8226648B2 (en) | 2007-12-31 | 2012-07-24 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Pressure-sensitive flexible polymer bipolar electrode |
US10085798B2 (en) * | 2006-12-29 | 2018-10-02 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation electrode with tactile sensor |
WO2008091983A2 (en) * | 2007-01-25 | 2008-07-31 | Thermage, Inc. | Treatment apparatus and methods for inducing microburn patterns in tissue |
US20080200969A1 (en) * | 2007-02-16 | 2008-08-21 | Thermage, Inc. | Temperature sensing apparatus and methods for treatment devices used to deliver high frequency energy to tissue |
US8688228B2 (en) | 2007-04-19 | 2014-04-01 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
EP2767308B1 (en) | 2007-04-19 | 2016-04-13 | Miramar Labs, Inc. | Devices, and systems for non-invasive delivery of microwave therapy |
US9241763B2 (en) | 2007-04-19 | 2016-01-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
WO2008131306A1 (en) | 2007-04-19 | 2008-10-30 | The Foundry, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
EP3391844A1 (en) | 2007-04-19 | 2018-10-24 | Miramar Labs, Inc. | Apparatus for reducing sweat production |
US8845630B2 (en) | 2007-06-15 | 2014-09-30 | Syneron Medical Ltd | Devices and methods for percutaneous energy delivery |
WO2009009661A1 (en) * | 2007-07-10 | 2009-01-15 | Thermage, Inc. | Treatment apparatus and methods for delivering high frequency energy across large tissue areas |
US8202272B2 (en) | 2007-07-19 | 2012-06-19 | Avedro, Inc. | Eye therapy system |
US8992516B2 (en) * | 2007-07-19 | 2015-03-31 | Avedro, Inc. | Eye therapy system |
US8506565B2 (en) | 2007-08-23 | 2013-08-13 | Covidien Lp | Electrosurgical device with LED adapter |
US8287579B2 (en) * | 2007-09-17 | 2012-10-16 | Thermage, Inc. | Method of using cryogenic compositions for cooling heated skin |
US9023014B2 (en) | 2007-09-21 | 2015-05-05 | Covidien Lp | Quick connect assembly for use between surgical handle assembly and surgical accessories |
JP5357161B2 (en) | 2007-09-21 | 2013-12-04 | コヴィディエン リミテッド パートナーシップ | Surgical equipment |
US8517241B2 (en) | 2010-04-16 | 2013-08-27 | Covidien Lp | Hand-held surgical devices |
US10498269B2 (en) | 2007-10-05 | 2019-12-03 | Covidien Lp | Powered surgical stapling device |
US10779818B2 (en) | 2007-10-05 | 2020-09-22 | Covidien Lp | Powered surgical stapling device |
EP2227197A4 (en) | 2007-12-05 | 2011-06-22 | Avedro Inc | Eye therapy system |
US8235987B2 (en) | 2007-12-05 | 2012-08-07 | Tyco Healthcare Group Lp | Thermal penetration and arc length controllable electrosurgical pencil |
US20090149930A1 (en) * | 2007-12-07 | 2009-06-11 | Thermage, Inc. | Apparatus and methods for cooling a treatment apparatus configured to non-invasively deliver electromagnetic energy to a patient's tissue |
US8180458B2 (en) * | 2007-12-17 | 2012-05-15 | Thermage, Inc. | Method and apparatus for digital signal processing for radio frequency surgery measurements |
EP2561819B1 (en) | 2008-01-17 | 2015-01-07 | Syneron Medical Ltd. | Hair removal apparatus for personal use |
US8409189B2 (en) * | 2008-01-23 | 2013-04-02 | Avedro, Inc. | System and method for reshaping an eye feature |
US8348935B2 (en) * | 2008-01-23 | 2013-01-08 | Avedro, Inc. | System and method for reshaping an eye feature |
US8469952B2 (en) | 2008-01-23 | 2013-06-25 | Avedro, Inc. | System and method for positioning an eye therapy device |
US20120022512A1 (en) * | 2008-01-24 | 2012-01-26 | Boris Vaynberg | Device, apparatus, and method of adipose tissue treatment |
WO2010029529A1 (en) * | 2008-09-11 | 2010-03-18 | Syneron Medical Ltd. | A device, apparatus, and method of adipose tissue treatment |
WO2009093230A2 (en) | 2008-01-24 | 2009-07-30 | Syneron Medical Ltd. | A device, apparatus, and method of adipose tissue treatment |
US8321031B1 (en) * | 2008-02-04 | 2012-11-27 | Ellman International, Inc | Radio-frequency treatment of skin tissue with temperature sensing |
US8597292B2 (en) | 2008-03-31 | 2013-12-03 | Covidien Lp | Electrosurgical pencil including improved controls |
US8636733B2 (en) | 2008-03-31 | 2014-01-28 | Covidien Lp | Electrosurgical pencil including improved controls |
US8632536B2 (en) | 2008-03-31 | 2014-01-21 | Covidien Lp | Electrosurgical pencil including improved controls |
US8515553B2 (en) * | 2008-04-28 | 2013-08-20 | Thermage, Inc. | Methods and apparatus for predictively controlling the temperature of a coolant delivered to a treatment device |
US20090275936A1 (en) * | 2008-05-01 | 2009-11-05 | David Muller | System and method for applying therapy to an eye using energy conduction |
US8285392B2 (en) * | 2008-06-19 | 2012-10-09 | Thermage, Inc. | Leakage-resistant tissue treatment apparatus and methods of using such tissue treatment apparatus |
US8121704B2 (en) * | 2008-06-19 | 2012-02-21 | Thermage, Inc. | Leakage-resistant tissue treatment apparatus and methods of using same |
US8162937B2 (en) | 2008-06-27 | 2012-04-24 | Tyco Healthcare Group Lp | High volume fluid seal for electrosurgical handpiece |
US8986323B2 (en) | 2008-08-22 | 2015-03-24 | Envy Medical, Inc. | Microdermabrasion system upgrade kit |
US8945104B2 (en) * | 2008-08-22 | 2015-02-03 | Envy Medical, Inc. | Microdermabrasion system with combination skin therapies |
US8702769B2 (en) * | 2008-09-11 | 2014-04-22 | Syneron Medical Ltd | Safe skin treatment apparatus for personal use and method for its use |
JP2012501788A (en) * | 2008-09-11 | 2012-01-26 | アヴェドロ・インコーポレーテッド | Eye treatment system |
US8398628B2 (en) * | 2008-09-19 | 2013-03-19 | Avedro, Inc. | Eye therapy system |
WO2010032235A1 (en) | 2008-09-21 | 2010-03-25 | Syneron Medical Ltd. | A method and apparatus for personal skin treatment |
US10028753B2 (en) | 2008-09-26 | 2018-07-24 | Relievant Medsystems, Inc. | Spine treatment kits |
US8366689B2 (en) | 2008-09-30 | 2013-02-05 | Avedro, Inc. | Method for making structural changes in corneal fibrils |
US8460278B2 (en) | 2008-10-01 | 2013-06-11 | Avedro, Inc. | Eye therapy system |
WO2010056848A1 (en) | 2008-11-11 | 2010-05-20 | Avedro, Inc. | Eye therapy system |
US8231620B2 (en) | 2009-02-10 | 2012-07-31 | Tyco Healthcare Group Lp | Extension cutting blade |
US9278230B2 (en) | 2009-02-25 | 2016-03-08 | Syneron Medical Ltd | Electrical skin rejuvenation |
WO2010114987A2 (en) * | 2009-04-01 | 2010-10-07 | The General Hospital Corporation | Apparatus and method for fat removal |
WO2010115121A1 (en) | 2009-04-02 | 2010-10-07 | Avedro, Inc. | Eye therapy system |
US8211103B2 (en) * | 2009-04-24 | 2012-07-03 | Megadyne Medical Products, Inc. | Electrosurgical instrument with adjustable power cable |
US8882768B2 (en) | 2009-04-24 | 2014-11-11 | Megadyne Medical Products, Inc. | Hand piece with adjustable utility conduit |
US8882767B2 (en) | 2009-04-24 | 2014-11-11 | Megadyne Medical Products, Inc. | Electrosurgical instrument with adjustable utility conduit |
ES2559809T3 (en) | 2009-09-18 | 2016-02-16 | Viveve Inc. | Vaginal Remodeling Device |
US8574277B2 (en) | 2009-10-21 | 2013-11-05 | Avedro Inc. | Eye therapy |
WO2011053768A2 (en) * | 2009-10-30 | 2011-05-05 | Avedro, Inc. | System and method for stabilizing corneal tissue after treatment |
US9060798B2 (en) * | 2009-11-16 | 2015-06-23 | Covidien Lp | Surgical forceps capable of adjusting sealing pressure based on vessel size |
US9050133B1 (en) | 2009-12-22 | 2015-06-09 | Envy Medical, Inc. | Skin treatment system with adjustable height wand |
WO2011116306A2 (en) | 2010-03-19 | 2011-09-22 | Avedro, Inc. | Systems and methods for applying and monitoring eye therapy |
BR112012026871A2 (en) * | 2010-04-19 | 2017-06-06 | Procter & Gamble | combined application of topical composition and energy to regulate mammalian skin condition |
EP2394693A1 (en) * | 2010-06-10 | 2011-12-14 | Golsen Limited | Electrical impulse stimulation device for the healing of wounds |
US8292150B2 (en) | 2010-11-02 | 2012-10-23 | Tyco Healthcare Group Lp | Adapter for powered surgical devices |
DE102010060336B4 (en) * | 2010-11-04 | 2015-03-26 | Erbe Elektromedizin Gmbh | Electrode device of an electrosurgical instrument |
DE102011014624B4 (en) | 2011-03-21 | 2013-09-05 | Viemedic Schönheitstechnik GmbH | Device for the cosmetic treatment of facial skin |
US9044308B2 (en) | 2011-05-24 | 2015-06-02 | Avedro, Inc. | Systems and methods for reshaping an eye feature |
EP2713849B1 (en) | 2011-06-02 | 2017-02-15 | Avedro, Inc. | Systems for monitoring time based photo active agent delivery or photo active marker presence |
US8768455B2 (en) * | 2011-06-13 | 2014-07-01 | Triune Ip Llc | Topical applicator |
US9314301B2 (en) | 2011-08-01 | 2016-04-19 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US9480492B2 (en) | 2011-10-25 | 2016-11-01 | Covidien Lp | Apparatus for endoscopic procedures |
US8672206B2 (en) | 2011-10-25 | 2014-03-18 | Covidien Lp | Apparatus for endoscopic procedures |
US11207089B2 (en) | 2011-10-25 | 2021-12-28 | Covidien Lp | Apparatus for endoscopic procedures |
US9492146B2 (en) | 2011-10-25 | 2016-11-15 | Covidien Lp | Apparatus for endoscopic procedures |
US9364231B2 (en) | 2011-10-27 | 2016-06-14 | Covidien Lp | System and method of using simulation reload to optimize staple formation |
KR101290606B1 (en) * | 2011-12-29 | 2013-07-30 | 김선환 | Stimulating Apparatus for Curing Skin Tissue |
US10390877B2 (en) | 2011-12-30 | 2019-08-27 | Relievant Medsystems, Inc. | Systems and methods for treating back pain |
CN103301567B (en) | 2012-03-16 | 2016-04-06 | 女康乐公司 | A kind of therapeutic apparatus repairing vagina tissue |
US10080563B2 (en) | 2012-06-01 | 2018-09-25 | Covidien Lp | Loading unit detection assembly and surgical device for use therewith |
US9868198B2 (en) | 2012-06-01 | 2018-01-16 | Covidien Lp | Hand held surgical handle assembly, surgical adapters for use between surgical handle assembly and surgical loading units, and methods of use |
US9597104B2 (en) | 2012-06-01 | 2017-03-21 | Covidien Lp | Handheld surgical handle assembly, surgical adapters for use between surgical handle assembly and surgical end effectors, and methods of use |
GB201210296D0 (en) | 2012-06-12 | 2012-07-25 | Gyrus Medical Ltd | Electrosurgical instrument & system |
US9364220B2 (en) | 2012-06-19 | 2016-06-14 | Covidien Lp | Apparatus for endoscopic procedures |
US9839480B2 (en) | 2012-07-09 | 2017-12-12 | Covidien Lp | Surgical adapter assemblies for use between surgical handle assembly and surgical end effectors |
US10492814B2 (en) | 2012-07-09 | 2019-12-03 | Covidien Lp | Apparatus for endoscopic procedures |
WO2013059837A2 (en) | 2012-07-16 | 2013-04-25 | Avedro, Inc. | Systems and methods for corneal cross-linking with pulsed light |
US9402604B2 (en) | 2012-07-20 | 2016-08-02 | Covidien Lp | Apparatus for endoscopic procedures |
DE102012015482A1 (en) * | 2012-08-07 | 2014-02-13 | Cinogy Gmbh | Electrode arrangement for a disabled plasma |
JP6301926B2 (en) | 2012-08-09 | 2018-03-28 | ユニバーシティ オブ アイオワ リサーチ ファウンデーション | Catheter, catheter system, and method for piercing tissue structure |
US10588691B2 (en) | 2012-09-12 | 2020-03-17 | Relievant Medsystems, Inc. | Radiofrequency ablation of tissue within a vertebral body |
US9421014B2 (en) | 2012-10-18 | 2016-08-23 | Covidien Lp | Loading unit velocity and position feedback |
JP6195625B2 (en) | 2012-11-05 | 2017-09-13 | リリーバント メドシステムズ、インコーポレイテッド | System and method for creating a curved pathway through bone and regulating nerves within the bone |
US9782187B2 (en) | 2013-01-18 | 2017-10-10 | Covidien Lp | Adapter load button lockout |
US10918364B2 (en) | 2013-01-24 | 2021-02-16 | Covidien Lp | Intelligent adapter assembly for use with an electromechanical surgical system |
US9421003B2 (en) | 2013-02-18 | 2016-08-23 | Covidien Lp | Apparatus for endoscopic procedures |
US9216013B2 (en) | 2013-02-18 | 2015-12-22 | Covidien Lp | Apparatus for endoscopic procedures |
US9492189B2 (en) | 2013-03-13 | 2016-11-15 | Covidien Lp | Apparatus for endoscopic procedures |
WO2014153149A1 (en) | 2013-03-14 | 2014-09-25 | Ellman International, Inc. | Electrosurgical systems and methods |
WO2014145148A2 (en) | 2013-03-15 | 2014-09-18 | Ellman International, Inc. | Surgical instruments and systems with multimodes of treatments and electrosurgical operation |
KR101743706B1 (en) | 2013-03-28 | 2017-06-07 | 주식회사 루트로닉 | A treatment apparatus using radio frequency energy |
US20140303608A1 (en) | 2013-04-08 | 2014-10-09 | Scientific Image Center Management, Inc. | System and method for providing treatment feedback for a thermal treatment device |
US9775610B2 (en) | 2013-04-09 | 2017-10-03 | Covidien Lp | Apparatus for endoscopic procedures |
US9700318B2 (en) | 2013-04-09 | 2017-07-11 | Covidien Lp | Apparatus for endoscopic procedures |
US9801646B2 (en) | 2013-05-30 | 2017-10-31 | Covidien Lp | Adapter load button decoupled from loading unit sensor |
US9498114B2 (en) | 2013-06-18 | 2016-11-22 | Avedro, Inc. | Systems and methods for determining biomechanical properties of the eye for applying treatment |
WO2014205145A1 (en) | 2013-06-18 | 2014-12-24 | Avedro, Inc. | Systems and methods for determining biomechanical properties of the eye for applying treatment |
US9797486B2 (en) | 2013-06-20 | 2017-10-24 | Covidien Lp | Adapter direct drive with manual retraction, lockout and connection mechanisms |
US10779885B2 (en) | 2013-07-24 | 2020-09-22 | Miradry. Inc. | Apparatus and methods for the treatment of tissue using microwave energy |
US9724151B2 (en) | 2013-08-08 | 2017-08-08 | Relievant Medsystems, Inc. | Modulating nerves within bone using bone fasteners |
US9955966B2 (en) | 2013-09-17 | 2018-05-01 | Covidien Lp | Adapter direct drive with manual retraction, lockout, and connection mechanisms for improper use prevention |
US10271840B2 (en) | 2013-09-18 | 2019-04-30 | Covidien Lp | Apparatus and method for differentiating between tissue and mechanical obstruction in a surgical instrument |
US9974540B2 (en) | 2013-10-18 | 2018-05-22 | Covidien Lp | Adapter direct drive twist-lock retention mechanism |
US9295522B2 (en) | 2013-11-08 | 2016-03-29 | Covidien Lp | Medical device adapter with wrist mechanism |
US10236616B2 (en) | 2013-12-04 | 2019-03-19 | Covidien Lp | Adapter assembly for interconnecting surgical devices and surgical attachments, and surgical systems thereof |
US9918713B2 (en) | 2013-12-09 | 2018-03-20 | Covidien Lp | Adapter assembly for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
EP3578119B1 (en) | 2013-12-11 | 2021-03-17 | Covidien LP | Wrist and jaw assemblies for robotic surgical systems |
CN105813580B (en) | 2013-12-12 | 2019-10-15 | 柯惠Lp公司 | Gear train for robotic surgical system |
US9808245B2 (en) | 2013-12-13 | 2017-11-07 | Covidien Lp | Coupling assembly for interconnecting an adapter assembly and a surgical device, and surgical systems thereof |
EP3091921B1 (en) | 2014-01-06 | 2019-06-19 | Farapulse, Inc. | Apparatus for renal denervation ablation |
JP6611722B2 (en) * | 2014-01-06 | 2019-11-27 | ファラパルス,インコーポレイテッド | Devices and methods for delivering therapeutic electrical impulses |
US10226305B2 (en) | 2014-02-12 | 2019-03-12 | Covidien Lp | Surgical end effectors and pulley assemblies thereof |
US9301691B2 (en) | 2014-02-21 | 2016-04-05 | Covidien Lp | Instrument for optically detecting tissue attributes |
EP3125785B1 (en) | 2014-03-31 | 2020-03-04 | Covidien LP | Wrist and jaw assemblies for robotic surgical systems |
US10164466B2 (en) | 2014-04-17 | 2018-12-25 | Covidien Lp | Non-contact surgical adapter electrical interface |
US10080552B2 (en) | 2014-04-21 | 2018-09-25 | Covidien Lp | Adapter assembly with gimbal for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
WO2015171921A2 (en) | 2014-05-07 | 2015-11-12 | Mickelson Steven R | Methods and apparatus for selective tissue ablation |
WO2015192027A1 (en) | 2014-06-12 | 2015-12-17 | Iowa Approach Inc. | Method and apparatus for rapid and selective transurethral tissue ablation |
EP3154464A4 (en) | 2014-06-12 | 2018-01-24 | Iowa Approach Inc. | Method and apparatus for rapid and selective tissue ablation with cooling |
US9987095B2 (en) | 2014-06-26 | 2018-06-05 | Covidien Lp | Adapter assemblies for interconnecting electromechanical handle assemblies and surgical loading units |
US10163589B2 (en) | 2014-06-26 | 2018-12-25 | Covidien Lp | Adapter assemblies for interconnecting surgical loading units and handle assemblies |
US10561418B2 (en) | 2014-06-26 | 2020-02-18 | Covidien Lp | Adapter assemblies for interconnecting surgical loading units and handle assemblies |
US9839425B2 (en) | 2014-06-26 | 2017-12-12 | Covidien Lp | Adapter assembly for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
US9763661B2 (en) | 2014-06-26 | 2017-09-19 | Covidien Lp | Adapter assembly for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
WO2016057225A1 (en) | 2014-10-07 | 2016-04-14 | Covidien Lp | Handheld electromechanical surgical system |
WO2016060983A1 (en) | 2014-10-14 | 2016-04-21 | Iowa Approach Inc. | Method and apparatus for rapid and safe pulmonary vein cardiac ablation |
US10729443B2 (en) | 2014-10-21 | 2020-08-04 | Covidien Lp | Adapter, extension, and connector assemblies for surgical devices |
US10226254B2 (en) | 2014-10-21 | 2019-03-12 | Covidien Lp | Adapter, extension, and connector assemblies for surgical devices |
US10085750B2 (en) | 2014-10-22 | 2018-10-02 | Covidien Lp | Adapter with fire rod J-hook lockout |
US9949737B2 (en) | 2014-10-22 | 2018-04-24 | Covidien Lp | Adapter assemblies for interconnecting surgical loading units and handle assemblies |
KR102545628B1 (en) | 2014-10-27 | 2023-06-20 | 아베드로 인코퍼레이티드 | Systems and methods for cross-linking treatments of an eye |
WO2016077747A1 (en) | 2014-11-13 | 2016-05-19 | Avedro, Inc. | Multipass virtually imaged phased array etalon |
US10111665B2 (en) | 2015-02-19 | 2018-10-30 | Covidien Lp | Electromechanical surgical systems |
US10190888B2 (en) | 2015-03-11 | 2019-01-29 | Covidien Lp | Surgical stapling instruments with linear position assembly |
US10226239B2 (en) | 2015-04-10 | 2019-03-12 | Covidien Lp | Adapter assembly with gimbal for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
US10327779B2 (en) | 2015-04-10 | 2019-06-25 | Covidien Lp | Adapter, extension, and connector assemblies for surgical devices |
US11432902B2 (en) | 2015-04-10 | 2022-09-06 | Covidien Lp | Surgical devices with moisture control |
US10426468B2 (en) | 2015-04-22 | 2019-10-01 | Covidien Lp | Handheld electromechanical surgical system |
US11278286B2 (en) | 2015-04-22 | 2022-03-22 | Covidien Lp | Handheld electromechanical surgical system |
WO2016172695A1 (en) | 2015-04-24 | 2016-10-27 | Avedro, Inc. | Systems and methods for photoactivating a photosensitizer applied to an eye |
US10028657B2 (en) | 2015-05-22 | 2018-07-24 | Avedro, Inc. | Systems and methods for monitoring cross-linking activity for corneal treatments |
CN108025011A (en) | 2015-07-21 | 2018-05-11 | 艾维德洛公司 | With the system and method for photosensitizing agents eyes |
US10751058B2 (en) | 2015-07-28 | 2020-08-25 | Covidien Lp | Adapter assemblies for surgical devices |
WO2017053363A1 (en) | 2015-09-25 | 2017-03-30 | Covidien Lp | Robotic surgical assemblies and instrument drive connectors thereof |
US10371238B2 (en) | 2015-10-09 | 2019-08-06 | Covidien Lp | Adapter assembly for surgical device |
US10413298B2 (en) | 2015-10-14 | 2019-09-17 | Covidien Lp | Adapter assembly for surgical devices |
US10292705B2 (en) | 2015-11-06 | 2019-05-21 | Covidien Lp | Surgical apparatus |
US10939952B2 (en) | 2015-11-06 | 2021-03-09 | Covidien Lp | Adapter, extension, and connector assemblies for surgical devices |
US10729435B2 (en) | 2015-11-06 | 2020-08-04 | Covidien Lp | Adapter assemblies for interconnecting surgical loading units and handle assemblies |
US10617411B2 (en) | 2015-12-01 | 2020-04-14 | Covidien Lp | Adapter assembly for surgical device |
US10433841B2 (en) | 2015-12-10 | 2019-10-08 | Covidien Lp | Adapter assembly for surgical device |
US10420554B2 (en) | 2015-12-22 | 2019-09-24 | Covidien Lp | Personalization of powered surgical devices |
US10253847B2 (en) | 2015-12-22 | 2019-04-09 | Covidien Lp | Electromechanical surgical devices with single motor drives and adapter assemblies therfor |
US10130423B1 (en) | 2017-07-06 | 2018-11-20 | Farapulse, Inc. | Systems, devices, and methods for focal ablation |
US10660702B2 (en) | 2016-01-05 | 2020-05-26 | Farapulse, Inc. | Systems, devices, and methods for focal ablation |
US10172673B2 (en) | 2016-01-05 | 2019-01-08 | Farapulse, Inc. | Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue |
US20170189097A1 (en) | 2016-01-05 | 2017-07-06 | Iowa Approach Inc. | Systems, apparatuses and methods for delivery of ablative energy to tissue |
US10314579B2 (en) | 2016-01-07 | 2019-06-11 | Covidien Lp | Adapter assemblies for interconnecting surgical loading units and handle assemblies |
US10524797B2 (en) | 2016-01-13 | 2020-01-07 | Covidien Lp | Adapter assembly including a removable trocar assembly |
US10660623B2 (en) | 2016-01-15 | 2020-05-26 | Covidien Lp | Centering mechanism for articulation joint |
US10508720B2 (en) | 2016-01-21 | 2019-12-17 | Covidien Lp | Adapter assembly with planetary gear drive for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
US10398439B2 (en) | 2016-02-10 | 2019-09-03 | Covidien Lp | Adapter, extension, and connector assemblies for surgical devices |
US10799239B2 (en) | 2016-05-09 | 2020-10-13 | Covidien Lp | Adapter assembly with pulley system and worm gear drive for interconnecting electromechanical surgical devices and surgical end effectors |
US10588610B2 (en) | 2016-05-10 | 2020-03-17 | Covidien Lp | Adapter assemblies for surgical devices |
US10736637B2 (en) | 2016-05-10 | 2020-08-11 | Covidien Lp | Brake for adapter assemblies for surgical devices |
US10702302B2 (en) | 2016-05-17 | 2020-07-07 | Covidien Lp | Adapter assembly including a removable trocar assembly |
US10463374B2 (en) | 2016-05-17 | 2019-11-05 | Covidien Lp | Adapter assembly for a flexible circular stapler |
WO2017205310A1 (en) | 2016-05-26 | 2017-11-30 | Covidien Lp | Robotic surgical assemblies |
WO2017218734A1 (en) | 2016-06-16 | 2017-12-21 | Iowa Approach, Inc. | Systems, apparatuses, and methods for guide wire delivery |
US20180333195A1 (en) * | 2017-05-18 | 2018-11-22 | Megadyne Medical Products, Inc. | Hand-held instrument with body-swivel |
US10653398B2 (en) | 2016-08-05 | 2020-05-19 | Covidien Lp | Adapter assemblies for surgical devices |
EP3522807A1 (en) | 2016-10-04 | 2019-08-14 | Avent, Inc. | Cooled rf probes |
USD843053S1 (en) * | 2016-11-08 | 2019-03-12 | Fenghua Bida Machinery Manufacture Co., Ltd. | Cosmetic sprayer |
US11116594B2 (en) | 2016-11-08 | 2021-09-14 | Covidien Lp | Surgical systems including adapter assemblies for interconnecting electromechanical surgical devices and end effectors |
KR101905830B1 (en) | 2016-11-15 | 2018-10-08 | 울산과학기술원 | Cryoanesthesia device, method for controlling cryoanesthesia device and temperature controller of coolant in cryoanesthesia device |
US10631945B2 (en) | 2017-02-28 | 2020-04-28 | Covidien Lp | Autoclavable load sensing device |
US10299790B2 (en) | 2017-03-03 | 2019-05-28 | Covidien Lp | Adapter with centering mechanism for articulation joint |
US11272929B2 (en) | 2017-03-03 | 2022-03-15 | Covidien Lp | Dynamically matching input and output shaft speeds of articulating adapter assemblies for surgical instruments |
US10660641B2 (en) | 2017-03-16 | 2020-05-26 | Covidien Lp | Adapter with centering mechanism for articulation joint |
US11896823B2 (en) | 2017-04-04 | 2024-02-13 | Btl Healthcare Technologies A.S. | Method and device for pelvic floor tissue treatment |
US9987081B1 (en) | 2017-04-27 | 2018-06-05 | Iowa Approach, Inc. | Systems, devices, and methods for signal generation |
US10617867B2 (en) | 2017-04-28 | 2020-04-14 | Farapulse, Inc. | Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue |
US10603035B2 (en) | 2017-05-02 | 2020-03-31 | Covidien Lp | Surgical loading unit including an articulating end effector |
US11324502B2 (en) | 2017-05-02 | 2022-05-10 | Covidien Lp | Surgical loading unit including an articulating end effector |
US10390858B2 (en) | 2017-05-02 | 2019-08-27 | Covidien Lp | Powered surgical device with speed and current derivative motor shut off |
US11311295B2 (en) | 2017-05-15 | 2022-04-26 | Covidien Lp | Adaptive powered stapling algorithm with calibration factor |
US20180333194A1 (en) * | 2017-05-16 | 2018-11-22 | Megadyne Medical Products, Inc. | Swivel instrument with flex circuit |
KR20180131355A (en) | 2017-05-30 | 2018-12-10 | 주식회사 리센스메디컬 | Disposable cooling medium |
WO2018221848A1 (en) | 2017-05-30 | 2018-12-06 | 주식회사 리센스메디컬 | Medical cooling device |
US10772700B2 (en) | 2017-08-23 | 2020-09-15 | Covidien Lp | Contactless loading unit detection |
US11583358B2 (en) | 2017-09-06 | 2023-02-21 | Covidien Lp | Boundary scaling of surgical robots |
CN115844523A (en) | 2017-09-12 | 2023-03-28 | 波士顿科学医学有限公司 | Systems, devices, and methods for ventricular focal ablation |
KR102517065B1 (en) | 2017-12-29 | 2023-04-03 | 주식회사 리센스메디컬 | Cooling generator |
EP3735196A4 (en) | 2018-01-04 | 2022-01-12 | Covidien LP | Robotic surgical instrument including high articulation wrist assembly with torque transmission and mechanical manipulation |
US11478298B2 (en) * | 2018-01-24 | 2022-10-25 | Medtronic Ardian Luxembourg S.A.R.L. | Controlled irrigation for neuromodulation systems and associated methods |
US11819259B2 (en) | 2018-02-07 | 2023-11-21 | Cynosure, Inc. | Methods and apparatus for controlled RF treatments and RF generator system |
US11160556B2 (en) | 2018-04-23 | 2021-11-02 | Covidien Lp | Threaded trocar for adapter assemblies |
KR102160855B1 (en) * | 2018-04-27 | 2020-09-28 | 울산과학기술원 | Medical cooling method and medical cooling device |
EP4154832A1 (en) | 2018-04-27 | 2023-03-29 | Recensmedical, Inc. | Cooling apparatus and cooling method |
US11534172B2 (en) | 2018-05-07 | 2022-12-27 | Covidien Lp | Electromechanical surgical stapler including trocar assembly release mechanism |
US11896230B2 (en) | 2018-05-07 | 2024-02-13 | Covidien Lp | Handheld electromechanical surgical device including load sensor having spherical ball pivots |
CN112087978B (en) | 2018-05-07 | 2023-01-17 | 波士顿科学医学有限公司 | Epicardial ablation catheter |
CN115836908A (en) | 2018-05-07 | 2023-03-24 | 波士顿科学医学有限公司 | Systems, devices, and methods for delivering ablation energy to tissue |
US11399839B2 (en) | 2018-05-07 | 2022-08-02 | Covidien Lp | Surgical devices including trocar lock and trocar connection indicator |
WO2019217317A1 (en) | 2018-05-07 | 2019-11-14 | Farapulse, Inc. | Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation |
KR102048384B1 (en) * | 2018-05-23 | 2020-01-08 | (주)클래시스 | Fluid rf electrode assembly for beauty treatment of skin and handpiece for beauty treatment of skin using the same |
BR112020025344A2 (en) | 2018-06-11 | 2021-03-09 | Aigain Beauty Ltd. | ARTIFICIAL INTELLIGENCE IN IMPROVED SKIN TENSIONING PROCEDURE |
US20190388091A1 (en) | 2018-06-21 | 2019-12-26 | Covidien Lp | Powered surgical devices including strain gauges incorporated into flex circuits |
AU2019204574A1 (en) | 2018-06-27 | 2020-01-23 | Viveve, Inc. | Methods for treating urinary stress incontinence |
US11241233B2 (en) | 2018-07-10 | 2022-02-08 | Covidien Lp | Apparatus for ensuring strain gauge accuracy in medical reusable device |
US20210113365A1 (en) * | 2018-07-27 | 2021-04-22 | Recensmedical, Inc. | Medical cooling device and cooling method using the same |
US11596496B2 (en) | 2018-08-13 | 2023-03-07 | Covidien Lp | Surgical devices with moisture control |
US11076858B2 (en) | 2018-08-14 | 2021-08-03 | Covidien Lp | Single use electronics for surgical devices |
KR102251808B1 (en) | 2018-08-17 | 2021-05-20 | 박성일 | Trigger type hand piece |
US11666479B2 (en) | 2018-08-19 | 2023-06-06 | Recensmedical, Inc. | Device for cooling anesthesia by chilled fluidic cooling medium |
US11403386B2 (en) | 2018-08-31 | 2022-08-02 | Bausch Health Ireland Limited | Encrypted memory device |
US10687892B2 (en) | 2018-09-20 | 2020-06-23 | Farapulse, Inc. | Systems, apparatuses, and methods for delivery of pulsed electric field ablative energy to endocardial tissue |
US11510669B2 (en) | 2020-09-29 | 2022-11-29 | Covidien Lp | Hand-held surgical instruments |
US11717276B2 (en) | 2018-10-30 | 2023-08-08 | Covidien Lp | Surgical devices including adapters and seals |
KR20200070095A (en) * | 2018-12-07 | 2020-06-17 | 울산과학기술원 | Cooling device and cooling method |
KR102140561B1 (en) * | 2019-01-07 | 2020-08-03 | (주)클래시스 | Rf electrode assembly for beauty treatment of skin and handpiece for beauty treatment of skin using the same |
US11241228B2 (en) | 2019-04-05 | 2022-02-08 | Covidien Lp | Surgical instrument including an adapter assembly and an articulating surgical loading unit |
US11369378B2 (en) | 2019-04-18 | 2022-06-28 | Covidien Lp | Surgical instrument including an adapter assembly and an articulating surgical loading unit |
USD921211S1 (en) | 2019-06-21 | 2021-06-01 | Recensmedical, Inc. | Medical cooling device |
USD921911S1 (en) | 2019-06-21 | 2021-06-08 | Recensmedical, Inc. | Medical cooling device |
US11464541B2 (en) | 2019-06-24 | 2022-10-11 | Covidien Lp | Retaining mechanisms for trocar assembly |
US11426168B2 (en) | 2019-07-05 | 2022-08-30 | Covidien Lp | Trocar coupling assemblies for a surgical stapler |
US11058429B2 (en) | 2019-06-24 | 2021-07-13 | Covidien Lp | Load sensing assemblies and methods of manufacturing load sensing assemblies |
US11446035B2 (en) | 2019-06-24 | 2022-09-20 | Covidien Lp | Retaining mechanisms for trocar assemblies |
US11123101B2 (en) | 2019-07-05 | 2021-09-21 | Covidien Lp | Retaining mechanisms for trocar assemblies |
USD1005484S1 (en) | 2019-07-19 | 2023-11-21 | Cynosure, Llc | Handheld medical instrument and docking base |
WO2021050767A1 (en) | 2019-09-12 | 2021-03-18 | Relievant Medsystems, Inc. | Systems and methods for tissue modulation |
US10625080B1 (en) | 2019-09-17 | 2020-04-21 | Farapulse, Inc. | Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation |
US11065047B2 (en) | 2019-11-20 | 2021-07-20 | Farapulse, Inc. | Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses |
US11497541B2 (en) | 2019-11-20 | 2022-11-15 | Boston Scientific Scimed, Inc. | Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses |
US10842572B1 (en) | 2019-11-25 | 2020-11-24 | Farapulse, Inc. | Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines |
US11564732B2 (en) | 2019-12-05 | 2023-01-31 | Covidien Lp | Tensioning mechanism for bipolar pencil |
US11737747B2 (en) | 2019-12-17 | 2023-08-29 | Covidien Lp | Hand-held surgical instruments |
US11583275B2 (en) | 2019-12-27 | 2023-02-21 | Covidien Lp | Surgical instruments including sensor assembly |
TW202139937A (en) * | 2020-03-05 | 2021-11-01 | 愛爾蘭商博士健康愛爾蘭有限公司 | Electrode assemblies with non-contact temperature sensing for thermal measursements |
US11504117B2 (en) | 2020-04-02 | 2022-11-22 | Covidien Lp | Hand-held surgical instruments |
US11278341B2 (en) | 2020-07-14 | 2022-03-22 | Recensmedical, Inc. | Method of safely using controlled cooling systems and devices |
KR102409465B1 (en) | 2020-07-28 | 2022-06-16 | 원텍 주식회사 | Apparatus for delivering high frequency energy |
USD968627S1 (en) | 2020-08-07 | 2022-11-01 | Recensmedical, Inc. | Medical cooling device |
USD968626S1 (en) | 2020-08-07 | 2022-11-01 | Recensmedical, Inc. | Medical cooling device |
USD977633S1 (en) | 2020-08-07 | 2023-02-07 | Recensmedical, Inc. | Cradle for a medical cooling device |
US11660091B2 (en) | 2020-09-08 | 2023-05-30 | Covidien Lp | Surgical device with seal assembly |
US11571192B2 (en) | 2020-09-25 | 2023-02-07 | Covidien Lp | Adapter assembly for surgical devices |
KR102375903B1 (en) * | 2021-05-10 | 2022-03-17 | 텐텍 주식회사 | Handpieces for skin treatment using high frequency |
CN113350696B (en) * | 2021-06-10 | 2024-01-19 | 上海茜茜纤美美容科技有限公司 | Ion explosion hand tool and system |
US11786248B2 (en) | 2021-07-09 | 2023-10-17 | Covidien Lp | Surgical stapling device including a buttress retention assembly |
US11819209B2 (en) | 2021-08-03 | 2023-11-21 | Covidien Lp | Hand-held surgical instruments |
US11862884B2 (en) | 2021-08-16 | 2024-01-02 | Covidien Lp | Surgical instrument with electrical connection |
KR20230128909A (en) | 2022-02-28 | 2023-09-05 | 원텍 주식회사 | A skin treatment device capable of automatically outputting high-frequency energy and control method |
Citations (91)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3327712A (en) * | 1961-09-15 | 1967-06-27 | Ira H Kaufman | Photocoagulation type fiber optical surgical device |
US3658051A (en) * | 1967-11-13 | 1972-04-25 | Kenneth Sheldon Maclean | Method of treating living things using high intensity pulsed magnetic field |
US3800802A (en) * | 1972-01-07 | 1974-04-02 | Int Medical Electronics Ltd | Short-wave therapy apparatus |
US3818129A (en) * | 1971-06-30 | 1974-06-18 | Hitachi Ltd | Laser imaging device |
US3930504A (en) * | 1973-12-12 | 1976-01-06 | Clinitex, Inc. | Portable light coagulator |
US4093975A (en) * | 1977-01-05 | 1978-06-06 | Roberts Wallace A | High-voltage apparatus for skin therapy |
US4140130A (en) * | 1977-05-31 | 1979-02-20 | Storm Iii Frederick K | Electrode structure for radio frequency localized heating of tumor bearing tissue |
US4186729A (en) * | 1977-11-25 | 1980-02-05 | Donald L. Morton & Associates | Deep heating electrode |
US4315503A (en) * | 1976-11-17 | 1982-02-16 | Electro-Biology, Inc. | Modification of the growth, repair and maintenance behavior of living tissues and cells by a specific and selective change in electrical environment |
US4316474A (en) * | 1979-08-17 | 1982-02-23 | Firma Electric Electronic Service Jens Spethmann | High frequency radiation therapy apparatus |
US4321930A (en) * | 1977-06-28 | 1982-03-30 | Duke University, Inc. | Apparatus for monitoring metabolism in body organs |
US4388924A (en) * | 1981-05-21 | 1983-06-21 | Weissman Howard R | Method for laser depilation |
US4444190A (en) * | 1980-11-24 | 1984-04-24 | Mutzhas Maximilian F | Device for the phototherapeutic treatment of hyperbilirubinemia |
US4497018A (en) * | 1983-05-05 | 1985-01-29 | Candela Corporation | Series inverter for capacitor charging |
US4506196A (en) * | 1980-11-13 | 1985-03-19 | Candela Corporation | Series inverter for capacitor charging |
US4522210A (en) * | 1982-04-02 | 1985-06-11 | Philippe Simonin | Method of skin treatment and device for carrying out the said method |
US4564011A (en) * | 1982-03-22 | 1986-01-14 | Leon Goldman | Laser optic device and method |
US4589423A (en) * | 1980-04-02 | 1986-05-20 | Bsd Medical Corporation | Apparatus for creating hyperthermia in tissue |
US4645980A (en) * | 1982-08-11 | 1987-02-24 | Yang Tai Her | Lighting system having photosensing timing switch circuit |
US4647830A (en) * | 1980-11-13 | 1987-03-03 | Candela Corporation | Series inverter circuit with timing responsive to reflective current |
US4653495A (en) * | 1984-01-13 | 1987-03-31 | Kabushiki Kaisha Toshiba | Laser medical apparatus |
US4671286A (en) * | 1983-03-04 | 1987-06-09 | Compagnie Francaise d'Electronique Medicale International SA (C.O.F.R.E.M. International SA) | RF therapy apparatus |
US4672969A (en) * | 1983-10-06 | 1987-06-16 | Sonomo Corporation | Laser healing method |
US4726377A (en) * | 1985-05-02 | 1988-02-23 | Jegers Viktor J | Modular control for tanning beds |
US4733660A (en) * | 1984-08-07 | 1988-03-29 | Medical Laser Research And Development Corporation | Laser system for providing target specific energy deposition and damage |
US4798215A (en) * | 1984-03-15 | 1989-01-17 | Bsd Medical Corporation | Hyperthermia apparatus |
US4810658A (en) * | 1984-06-13 | 1989-03-07 | Ares-Serono Research & Development | Photometric instruments, their use in methods of optical analysis, and ancillary devices therefor |
US4829262A (en) * | 1984-10-25 | 1989-05-09 | Candela Laser Corporation | Long pulse tunable light amplifier |
US4835749A (en) * | 1985-09-11 | 1989-05-30 | Welton Truett T | Safe tanning lamp control system |
US4901720A (en) * | 1986-04-08 | 1990-02-20 | C. R. Bard, Inc. | Power control for beam-type electrosurgical unit |
US5008579A (en) * | 1989-03-03 | 1991-04-16 | E. F. Johnson Co. | Light emitting polymer electrical energy source |
US5011483A (en) * | 1989-06-26 | 1991-04-30 | Dennis Sleister | Combined electrosurgery and laser beam delivery device |
US5012816A (en) * | 1989-08-31 | 1991-05-07 | Gabor Lederer | Electronic acupuncture device |
US5083093A (en) * | 1990-06-22 | 1992-01-21 | Varian Associates, Inc. | Circuit for coupling energy to pulse forming network or capacitor |
US5085227A (en) * | 1989-02-15 | 1992-02-04 | Gerard Ramon | Conductive cutaneous coating for applying electric currents for therapeutic or beauty treatment |
US5097844A (en) * | 1980-04-02 | 1992-03-24 | Bsd Medical Corporation | Hyperthermia apparatus having three-dimensional focusing |
US5113462A (en) * | 1990-06-01 | 1992-05-12 | Candela Laser Corporation | High energy fiber optica coupler |
US5186181A (en) * | 1990-07-27 | 1993-02-16 | Cafiero Franconi | Radio frequency thermotherapy |
US5194723A (en) * | 1991-12-24 | 1993-03-16 | Maxwell Laboratories, Inc. | Photoacoustic control of a pulsed light material removal process |
US5281798A (en) * | 1991-12-24 | 1994-01-25 | Maxwell Laboratories, Inc. | Method and system for selective removal of material coating from a substrate using a flashlamp |
US5282797A (en) * | 1989-05-30 | 1994-02-01 | Cyrus Chess | Method for treating cutaneous vascular lesions |
US5290274A (en) * | 1992-06-16 | 1994-03-01 | Laser Medical Technology, Inc. | Laser apparatus for medical and dental treatments |
US5290273A (en) * | 1991-08-12 | 1994-03-01 | Tan Oon T | Laser treatment method for removing pigement containing lesions from the skin of a living human |
US5312395A (en) * | 1990-03-14 | 1994-05-17 | Boston University | Method of treating pigmented lesions using pulsed irradiation |
US5383874A (en) * | 1991-11-08 | 1995-01-24 | Ep Technologies, Inc. | Systems for identifying catheters and monitoring their use |
US5396887A (en) * | 1993-09-23 | 1995-03-14 | Cardiac Pathways Corporation | Apparatus and method for detecting contact pressure |
US5401272A (en) * | 1992-09-25 | 1995-03-28 | Envision Surgical Systems, Inc. | Multimodality probe with extendable bipolar electrodes |
US5400791A (en) * | 1991-10-11 | 1995-03-28 | Candela Laser Corporation | Infrared fundus video angiography system |
US5405368A (en) * | 1992-10-20 | 1995-04-11 | Esc Inc. | Method and apparatus for therapeutic electromagnetic treatment |
US5484432A (en) * | 1985-09-27 | 1996-01-16 | Laser Biotech, Inc. | Collagen treatment apparatus |
US5489279A (en) * | 1994-03-21 | 1996-02-06 | Dusa Pharmaceuticals, Inc. | Method of applying photodynamic therapy to dermal lesion |
US5507790A (en) * | 1994-03-21 | 1996-04-16 | Weiss; William V. | Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism |
US5509916A (en) * | 1994-08-12 | 1996-04-23 | Valleylab Inc. | Laser-assisted electrosurgery system |
US5514130A (en) * | 1994-10-11 | 1996-05-07 | Dorsal Med International | RF apparatus for controlled depth ablation of soft tissue |
US5595568A (en) * | 1995-02-01 | 1997-01-21 | The General Hospital Corporation | Permanent hair removal using optical pulses |
US5620478A (en) * | 1992-10-20 | 1997-04-15 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5626631A (en) * | 1992-10-20 | 1997-05-06 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5707403A (en) * | 1993-02-24 | 1998-01-13 | Star Medical Technologies, Inc. | Method for the laser treatment of subsurface blood vessels |
US5720772A (en) * | 1992-10-20 | 1998-02-24 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5723803A (en) * | 1993-09-30 | 1998-03-03 | Yamaha Corporation | Automatic performance apparatus |
US5725565A (en) * | 1995-12-04 | 1998-03-10 | Smith; Daniel E. | Tanning bed safety device |
US5728141A (en) * | 1994-05-04 | 1998-03-17 | Indiba, S.A. | Electrotherapy apparatus |
US5735844A (en) * | 1995-02-01 | 1998-04-07 | The General Hospital Corporation | Hair removal using optical pulses |
US5755753A (en) * | 1995-05-05 | 1998-05-26 | Thermage, Inc. | Method for controlled contraction of collagen tissue |
US5885273A (en) * | 1995-03-29 | 1999-03-23 | Esc Medical Systems, Ltd. | Method for depilation using pulsed electromagnetic radiation |
US6009876A (en) * | 1997-05-20 | 2000-01-04 | Yavitz; Edward Q. | Method for modifying and reshaping collagen beneath the surface of skin |
US6014579A (en) * | 1997-07-21 | 2000-01-11 | Cardiac Pathways Corp. | Endocardial mapping catheter with movable electrode |
USRE36634E (en) * | 1991-12-12 | 2000-03-28 | Ghaffari; Shahriar | Optical system for treatment of vascular lesions |
US6047215A (en) * | 1998-03-06 | 2000-04-04 | Sonique Surgical Systems, Inc. | Method and apparatus for electromagnetically assisted liposuction |
US6053909A (en) * | 1998-03-27 | 2000-04-25 | Shadduck; John H. | Ionothermal delivery system and technique for medical procedures |
US6053910A (en) * | 1996-10-30 | 2000-04-25 | Megadyne Medical Products, Inc. | Capacitive reusable electrosurgical return electrode |
US6171332B1 (en) * | 1992-10-23 | 2001-01-09 | Photo Therapeutics Limited | Light source |
US6214034B1 (en) * | 1996-09-04 | 2001-04-10 | Radiancy, Inc. | Method of selective photothermolysis |
US6350276B1 (en) * | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
US6377854B1 (en) * | 1995-05-05 | 2002-04-23 | Thermage, Inc. | Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers |
US6387380B1 (en) * | 1995-05-05 | 2002-05-14 | Thermage, Inc. | Apparatus for controlled contraction of collagen tissue |
US6514243B1 (en) * | 1992-10-20 | 2003-02-04 | Lumenis Ltd. | Method and apparatus for electromagnetic treatment of the skin, including hair depilation |
US6533781B2 (en) * | 1997-12-23 | 2003-03-18 | Team Medical Llc | Electrosurgical instrument |
US6544258B2 (en) * | 1996-10-30 | 2003-04-08 | Mega-Dyne Medical Products, Inc. | Pressure sore pad having self-limiting electrosurgical return electrode properties and optional heating/cooling capabilities |
US6567262B2 (en) * | 2001-06-01 | 2003-05-20 | Active Cool Ltd. | Liquid cooled TEC based system and method for cooling heat sensitive elements |
US20040002704A1 (en) * | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Treatment apparatus with electromagnetic energy delivery device and non-volatile memory |
US20040000316A1 (en) * | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US20040002705A1 (en) * | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US6684107B1 (en) * | 2001-08-01 | 2004-01-27 | Voyager Medical Corporation | Wrinkle-reducing system |
US6690976B2 (en) * | 2000-04-13 | 2004-02-10 | Celsion Corporation | Thermotherapy method for treatment and prevention of breast cancer and cancer in other organs |
US20040030332A1 (en) * | 1996-01-05 | 2004-02-12 | Knowlton Edward W. | Handpiece with electrode and non-volatile memory |
US20040034346A1 (en) * | 1996-01-05 | 2004-02-19 | Stern Roger A. | RF device with thermo-electric cooler |
US6702808B1 (en) * | 2000-09-28 | 2004-03-09 | Syneron Medical Ltd. | Device and method for treating skin |
US6981970B2 (en) * | 2002-12-16 | 2006-01-03 | Msq (M2) Ltd. | Device and method for treating skin |
US6997923B2 (en) * | 2000-12-28 | 2006-02-14 | Palomar Medical Technologies, Inc. | Method and apparatus for EMR treatment |
US7022121B2 (en) * | 1999-03-09 | 2006-04-04 | Thermage, Inc. | Handpiece for treatment of tissue |
Family Cites Families (149)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3831604A (en) | 1973-04-18 | 1974-08-27 | C Neefe | Method of reshaping the cornea |
US4074718A (en) | 1976-03-17 | 1978-02-21 | Valleylab, Inc. | Electrosurgical instrument |
US4164226A (en) | 1976-08-25 | 1979-08-14 | Robert Tapper | Iontophoretic burn-protection electrode structure |
USRE32849E (en) | 1978-04-13 | 1989-01-31 | Litton Systems, Inc. | Method for fabricating multi-layer optical films |
US4346715A (en) | 1978-07-12 | 1982-08-31 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Hyperthermia heating apparatus |
CA1105565A (en) * | 1978-09-12 | 1981-07-21 | Kaufman (John G.) Hospital Products Ltd. | Electrosurgical electrode |
US4341227A (en) | 1979-01-11 | 1982-07-27 | Bsd Corporation | System for irradiating living tissue or simulations thereof |
US4585237A (en) | 1979-01-15 | 1986-04-29 | Hastings Manufacturing Company | Piston and oil control ring therefor |
US4290435A (en) | 1979-09-07 | 1981-09-22 | Thermatime A.G. | Internally cooled electrode for hyperthermal treatment and method of use |
US4343301A (en) | 1979-10-04 | 1982-08-10 | Robert Indech | Subcutaneous neural stimulation or local tissue destruction |
US4375220A (en) | 1980-05-09 | 1983-03-01 | Matvias Fredrick M | Microwave applicator with cooling mechanism for intracavitary treatment of cancer |
US4381007A (en) | 1981-04-30 | 1983-04-26 | The United States Of America As Represented By The United States Department Of Energy | Multipolar corneal-shaping electrode with flexible removable skirt |
US4441486A (en) | 1981-10-27 | 1984-04-10 | Board Of Trustees Of Leland Stanford Jr. University | Hyperthermia system |
US4756310A (en) | 1982-05-28 | 1988-07-12 | Hemodynamics Technology, Inc. | System for cooling an area of the surface of an object |
JPS599626A (en) * | 1982-07-08 | 1984-01-19 | Ricoh Co Ltd | Optical deflector |
CA1244889A (en) | 1983-01-24 | 1988-11-15 | Kureha Chemical Ind Co Ltd | Device for hyperthermia |
US4545368A (en) | 1983-04-13 | 1985-10-08 | Rand Robert W | Induction heating method for use in causing necrosis of neoplasm |
US4646737A (en) * | 1983-06-13 | 1987-03-03 | Laserscope, Inc. | Localized heat applying medical device |
JPS6055966A (en) | 1983-09-05 | 1985-04-01 | オリンパス光学工業株式会社 | Medical electrode apparatus |
US4556070A (en) | 1983-10-31 | 1985-12-03 | Varian Associates, Inc. | Hyperthermia applicator for treatment with microwave energy and ultrasonic wave energy |
JPS6137259A (en) | 1984-07-31 | 1986-02-22 | 菊地 真 | Heating apparatus for hyperthermia |
US4754754A (en) | 1984-08-20 | 1988-07-05 | Garito Jon C | Electrosurgical handpiece for blades and needles |
US4655215A (en) * | 1985-03-15 | 1987-04-07 | Harold Pike | Hand control for electrosurgical electrodes |
IT206759Z2 (en) | 1985-07-08 | 1987-10-01 | Indiba Sa | ELECTRONIC DEVICE FOR COSMETIC MEDICAL THERAPY. |
US5137530A (en) | 1985-09-27 | 1992-08-11 | Sand Bruce J | Collagen treatment apparatus |
US4976709A (en) | 1988-12-15 | 1990-12-11 | Sand Bruce J | Method for collagen treatment |
US5304169A (en) | 1985-09-27 | 1994-04-19 | Laser Biotech, Inc. | Method for collagen shrinkage |
GB8529446D0 (en) | 1985-11-29 | 1986-01-08 | Univ Aberdeen | Divergent ultrasound arrays |
US4891820A (en) * | 1985-12-19 | 1990-01-02 | Rofin-Sinar, Inc. | Fast axial flow laser circulating system |
US4709372A (en) | 1985-12-19 | 1987-11-24 | Spectra-Physics, Inc. | Fast axial flow laser circulating system |
US4709701A (en) | 1986-04-15 | 1987-12-01 | Medical Research & Development Associates | Apparatus for medical treatment by hyperthermia |
JPS62280781A (en) * | 1986-05-30 | 1987-12-05 | Mita Ind Co Ltd | Developing device for image forming machine |
US4962761A (en) | 1987-02-24 | 1990-10-16 | Golden Theodore A | Thermal bandage |
US5003991A (en) | 1987-03-31 | 1991-04-02 | Olympus Optical Co., Ltd. | Hyperthermia apparatus |
JPS6456060A (en) | 1987-08-27 | 1989-03-02 | Hayashibara Takeshi | Low frequency medical treatment device |
JPH0669429B2 (en) * | 1987-12-16 | 1994-09-07 | リンナイ株式会社 | Bath |
US4957480A (en) | 1988-02-02 | 1990-09-18 | Universal Health Products, Inc. | Method of facial toning |
US5143063A (en) | 1988-02-09 | 1992-09-01 | Fellner Donald G | Method of removing adipose tissue from the body |
US4864098A (en) | 1988-05-19 | 1989-09-05 | Rofin-Sinar, Inc. | High powered beam dump |
US4881543A (en) | 1988-06-28 | 1989-11-21 | Massachusetts Institute Of Technology | Combined microwave heating and surface cooling of the cornea |
US6066130A (en) * | 1988-10-24 | 2000-05-23 | The General Hospital Corporation | Delivering laser energy |
US5486172A (en) | 1989-05-30 | 1996-01-23 | Chess; Cyrus | Apparatus for treating cutaneous vascular lesions |
US5041110A (en) * | 1989-07-10 | 1991-08-20 | Beacon Laboratories, Inc. | Cart for mobilizing and interfacing use of an electrosurgical generator and inert gas supply |
US5364394A (en) | 1989-12-21 | 1994-11-15 | Mehl Thomas L | Method of removing hair from the body and inhibiting future growth |
US5131904A (en) | 1990-05-04 | 1992-07-21 | Richard Markoll | Treatment of arthritis with magnetic field therapy and apparatus therefor |
US5100402A (en) * | 1990-10-05 | 1992-03-31 | Megadyne Medical Products, Inc. | Electrosurgical laparoscopic cauterization electrode |
US5304171A (en) * | 1990-10-18 | 1994-04-19 | Gregory Kenton W | Catheter devices and methods for delivering |
US5300097A (en) * | 1991-02-13 | 1994-04-05 | Lerner Ethan A | Fiber optic psoriasis treatment device |
US5190031A (en) * | 1991-03-11 | 1993-03-02 | Raul Guibert | Universal thermotherapy applicator |
US5107832A (en) | 1991-03-11 | 1992-04-28 | Raul Guibert | Universal thermotherapy applicator |
US5136676A (en) | 1991-05-01 | 1992-08-04 | Coherent, Inc. | Coupler for a laser delivery system |
US5190517A (en) | 1991-06-06 | 1993-03-02 | Valleylab Inc. | Electrosurgical and ultrasonic surgical system |
US5234428A (en) * | 1991-06-11 | 1993-08-10 | Kaufman David I | Disposable electrocautery/cutting instrument with integral continuous smoke evacuation |
US5249192A (en) | 1991-06-27 | 1993-09-28 | Laserscope | Multiple frequency medical laser |
FR2680965B1 (en) | 1991-09-05 | 1993-11-12 | Gabriel Bernaz | APPARATUS AND METHOD FOR TREATING SKIN. |
US5370642A (en) | 1991-09-25 | 1994-12-06 | Keller; Gregory S. | Method of laser cosmetic surgery |
US5249575A (en) | 1991-10-21 | 1993-10-05 | Adm Tronics Unlimited, Inc. | Corona discharge beam thermotherapy system |
US6210402B1 (en) * | 1995-11-22 | 2001-04-03 | Arthrocare Corporation | Methods for electrosurgical dermatological treatment |
US5366443A (en) | 1992-01-07 | 1994-11-22 | Thapliyal And Eggers Partners | Method and apparatus for advancing catheters through occluded body lumens |
US5230334A (en) | 1992-01-22 | 1993-07-27 | Summit Technology, Inc. | Method and apparatus for generating localized hyperthermia |
CA2158739C (en) | 1992-03-20 | 2004-09-21 | R. Rox Anderson | Laser illuminator |
US5423807A (en) | 1992-04-16 | 1995-06-13 | Implemed, Inc. | Cryogenic mapping and ablation catheter |
US5562720A (en) | 1992-05-01 | 1996-10-08 | Vesta Medical, Inc. | Bipolar/monopolar endometrial ablation device and method |
US5496314A (en) * | 1992-05-01 | 1996-03-05 | Hemostatic Surgery Corporation | Irrigation and shroud arrangement for electrically powered endoscopic probes |
WO1994002077A2 (en) * | 1992-07-15 | 1994-02-03 | Angelase, Inc. | Ablation catheter system |
US5556377A (en) | 1992-08-12 | 1996-09-17 | Vidamed, Inc. | Medical probe apparatus with laser and/or microwave monolithic integrated circuit probe |
DE59300999D1 (en) * | 1992-09-18 | 1996-01-04 | Basf Ag | Process for the preparation of N-hydroxy-N'-diazenium oxides. |
US5342357A (en) | 1992-11-13 | 1994-08-30 | American Cardiac Ablation Co., Inc. | Fluid cooled electrosurgical cauterization system |
US5334193A (en) | 1992-11-13 | 1994-08-02 | American Cardiac Ablation Co., Inc. | Fluid cooled ablation catheter |
US5348554A (en) | 1992-12-01 | 1994-09-20 | Cardiac Pathways Corporation | Catheter for RF ablation with cooled electrode |
US5360447A (en) | 1993-02-03 | 1994-11-01 | Coherent, Inc. | Laser assisted hair transplant method |
US5527350A (en) | 1993-02-24 | 1996-06-18 | Star Medical Technologies, Inc. | Pulsed infrared laser treatment of psoriasis |
US5476495A (en) * | 1993-03-16 | 1995-12-19 | Ep Technologies, Inc. | Cardiac mapping and ablation systems |
US5395363A (en) * | 1993-06-29 | 1995-03-07 | Utah Medical Products | Diathermy coagulation and ablation apparatus and method |
US5397327A (en) | 1993-07-27 | 1995-03-14 | Coherent, Inc. | Surgical laser handpiece for slit incisions |
US5496312A (en) | 1993-10-07 | 1996-03-05 | Valleylab Inc. | Impedance and temperature generator control |
US5628744A (en) * | 1993-12-21 | 1997-05-13 | Laserscope | Treatment beam handpiece |
US5462521A (en) | 1993-12-21 | 1995-10-31 | Angeion Corporation | Fluid cooled and perfused tip for a catheter |
US5571216A (en) | 1994-01-19 | 1996-11-05 | The General Hospital Corporation | Methods and apparatus for joining collagen-containing materials |
US5556612A (en) | 1994-03-15 | 1996-09-17 | The General Hospital Corporation | Methods for phototherapeutic treatment of proliferative skin diseases |
US5456260A (en) | 1994-04-05 | 1995-10-10 | The General Hospital Corporation | Fluorescence detection of cell proliferation |
JP3263275B2 (en) * | 1994-04-05 | 2002-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Apparatus for laser treatment of living tissue and laser treatment apparatus for flame-like nevus |
US5464436A (en) | 1994-04-28 | 1995-11-07 | Lasermedics, Inc. | Method of performing laser therapy |
US5458596A (en) | 1994-05-06 | 1995-10-17 | Dorsal Orthopedic Corporation | Method and apparatus for controlled contraction of soft tissue |
US5730719A (en) * | 1994-05-09 | 1998-03-24 | Somnus Medical Technologies, Inc. | Method and apparatus for cosmetically remodeling a body structure |
US5531739A (en) | 1994-09-23 | 1996-07-02 | Coherent, Inc. | Method of treating veins |
US5522813A (en) | 1994-09-23 | 1996-06-04 | Coherent, Inc. | Method of treating veins |
US5746735A (en) * | 1994-10-26 | 1998-05-05 | Cynosure, Inc. | Ultra long pulsed dye laser device for treatment of ectatic vessels and method therefor |
WO1996017656A1 (en) * | 1994-12-09 | 1996-06-13 | Cynosure, Inc. | Near-infrared selective photothermolysis for vascular targets |
US5558667A (en) | 1994-12-14 | 1996-09-24 | Coherent, Inc. | Method and apparatus for treating vascular lesions |
US5880880A (en) * | 1995-01-13 | 1999-03-09 | The General Hospital Corp. | Three-dimensional scanning confocal laser microscope |
US5599342A (en) * | 1995-01-27 | 1997-02-04 | Candela Laser Corporation | Method for treating pigmentation abnormalities using pulsed laser radiation with an elongated cross-section and apparatus for providing same |
US5630426A (en) | 1995-03-03 | 1997-05-20 | Neovision Corporation | Apparatus and method for characterization and treatment of tumors |
US5554172A (en) * | 1995-05-09 | 1996-09-10 | The Larren Corporation | Directed energy surgical method and assembly |
AU5740496A (en) * | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
US5624435A (en) * | 1995-06-05 | 1997-04-29 | Cynosure, Inc. | Ultra-long flashlamp-excited pulse dye laser for therapy and method therefor |
US5879376A (en) * | 1995-07-12 | 1999-03-09 | Luxar Corporation | Method and apparatus for dermatology treatment |
US5964749A (en) * | 1995-09-15 | 1999-10-12 | Esc Medical Systems Ltd. | Method and apparatus for skin rejuvenation and wrinkle smoothing |
US6228078B1 (en) | 1995-11-22 | 2001-05-08 | Arthrocare Corporation | Methods for electrosurgical dermatological treatment |
US5837001A (en) * | 1995-12-08 | 1998-11-17 | C. R. Bard | Radio frequency energy delivery system for multipolar electrode catheters |
US5879346A (en) * | 1995-12-18 | 1999-03-09 | Esc Medical Systems, Ltd. | Hair removal by selective photothermolysis with an alexandrite laser |
US7229436B2 (en) | 1996-01-05 | 2007-06-12 | Thermage, Inc. | Method and kit for treatment of tissue |
US7189230B2 (en) | 1996-01-05 | 2007-03-13 | Thermage, Inc. | Method for treating skin and underlying tissue |
US6266551B1 (en) * | 1996-02-15 | 2001-07-24 | Biosense, Inc. | Catheter calibration and usage monitoring system |
US5609573A (en) | 1996-02-28 | 1997-03-11 | Conmed Corporation | Electrosurgical suction/irrigation instrument |
KR100376650B1 (en) * | 1996-04-09 | 2003-08-25 | 싸이노슈어, 인코포레이티드 | Alexander laser system for the treatment of skin pathological specimens |
US5871479A (en) * | 1996-11-07 | 1999-02-16 | Cynosure, Inc. | Alexandrite laser system for hair removal and method therefor |
US5743901A (en) * | 1996-05-15 | 1998-04-28 | Star Medical Technologies, Inc. | High fluence diode laser device and method for the fabrication and use thereof |
US5976123A (en) * | 1996-07-30 | 1999-11-02 | Laser Aesthetics, Inc. | Heart stabilization |
US6228075B1 (en) * | 1996-11-07 | 2001-05-08 | Cynosure, Inc. | Alexandrite laser system for hair removal |
US6015404A (en) * | 1996-12-02 | 2000-01-18 | Palomar Medical Technologies, Inc. | Laser dermatology with feedback control |
US7204832B2 (en) * | 1996-12-02 | 2007-04-17 | Pálomar Medical Technologies, Inc. | Cooling system for a photo cosmetic device |
US6273884B1 (en) * | 1997-05-15 | 2001-08-14 | Palomar Medical Technologies, Inc. | Method and apparatus for dermatology treatment |
US6162211A (en) * | 1996-12-05 | 2000-12-19 | Thermolase Corporation | Skin enhancement using laser light |
US5906609A (en) * | 1997-02-05 | 1999-05-25 | Sahar Technologies | Method for delivering energy within continuous outline |
US5885274A (en) * | 1997-06-24 | 1999-03-23 | New Star Lasers, Inc. | Filament lamp for dermatological treatment |
GB9900964D0 (en) * | 1999-01-15 | 1999-03-10 | Gyrus Medical Ltd | An electrosurgical system |
US6168590B1 (en) * | 1997-08-12 | 2001-01-02 | Y-Beam Technologies, Inc. | Method for permanent hair removal |
AU732188B2 (en) * | 1997-08-13 | 2001-04-12 | Surx, Inc. | Noninvasive devices, methods, and systems for shrinking of tissues |
US6007532A (en) * | 1997-08-29 | 1999-12-28 | 3M Innovative Properties Company | Method and apparatus for detecting loss of contact of biomedical electrodes with patient skin |
IL122840A (en) * | 1997-12-31 | 2002-04-21 | Radiancy Inc | Apparatus and methods for removing hair |
AU3450799A (en) * | 1998-03-12 | 1999-09-27 | Palomar Medical Technologies, Inc. | System for electromagnetic radiation of the skin |
ES2403359T3 (en) * | 1998-03-27 | 2013-05-17 | The General Hospital Corporation | Procedure and apparatus for the selective determination of lipid rich tissues |
US6139543A (en) * | 1998-07-22 | 2000-10-31 | Endovasix, Inc. | Flow apparatus for the disruption of occlusions |
US6212433B1 (en) * | 1998-07-28 | 2001-04-03 | Radiotherapeutics Corporation | Method for treating tumors near the surface of an organ |
US6139569A (en) | 1998-07-31 | 2000-10-31 | Surx, Inc. | Interspersed heating/cooling to shrink tissues for incontinence |
US6126655A (en) * | 1998-08-11 | 2000-10-03 | The General Hospital Corporation | Apparatus and method for selective laser-induced heating of biological tissue |
US6936044B2 (en) * | 1998-11-30 | 2005-08-30 | Light Bioscience, Llc | Method and apparatus for the stimulation of hair growth |
US6183773B1 (en) * | 1999-01-04 | 2001-02-06 | The General Hospital Corporation | Targeting of sebaceous follicles as a treatment of sebaceous gland disorders |
US6200308B1 (en) * | 1999-01-29 | 2001-03-13 | Candela Corporation | Dynamic cooling of tissue for radiation treatment |
US20020156471A1 (en) * | 1999-03-09 | 2002-10-24 | Stern Roger A. | Method for treatment of tissue |
JP4102031B2 (en) * | 1999-03-09 | 2008-06-18 | サーメイジ インコーポレイテッド | Apparatus and method for treating tissue |
US6569155B1 (en) * | 1999-03-15 | 2003-05-27 | Altus Medical, Inc. | Radiation delivery module and dermal tissue treatment method |
US6383176B1 (en) * | 1999-03-15 | 2002-05-07 | Altus Medical, Inc. | Hair removal device and method |
US6533775B1 (en) * | 1999-05-05 | 2003-03-18 | Ioana M. Rizoiu | Light-activated hair treatment and removal device |
US6235024B1 (en) * | 1999-06-21 | 2001-05-22 | Hosheng Tu | Catheters system having dual ablation capability |
US6451007B1 (en) * | 1999-07-29 | 2002-09-17 | Dale E. Koop | Thermal quenching of tissue |
US20020016601A1 (en) * | 2000-01-03 | 2002-02-07 | Shadduck John H. | Instruments and techniques for inducing neocollagenesis in skin treatments |
US6706032B2 (en) * | 2000-06-08 | 2004-03-16 | Massachusetts Institute Of Technology | Localized molecular and ionic transport to and from tissues |
US6702838B1 (en) * | 2000-09-18 | 2004-03-09 | Lumenis Inc. | Method of treating hypotrophic scars enlarged pores |
US6529543B1 (en) * | 2000-11-21 | 2003-03-04 | The General Hospital Corporation | Apparatus for controlling laser penetration depth |
US7217266B2 (en) * | 2001-05-30 | 2007-05-15 | Anderson R Rox | Apparatus and method for laser treatment with spectroscopic feedback |
WO2003003903A2 (en) * | 2001-07-02 | 2003-01-16 | Palomar Medical Technologies, Inc. | Laser device for medical/cosmetic procedures |
US6939344B2 (en) * | 2001-08-02 | 2005-09-06 | Syneron Medical Ltd. | Method for controlling skin temperature during thermal treatment |
US7094252B2 (en) * | 2001-08-21 | 2006-08-22 | Cooltouch Incorporated | Enhanced noninvasive collagen remodeling |
US6685927B2 (en) * | 2001-09-27 | 2004-02-03 | Ceramoptec Industries, Inc. | Topical application of chromophores for hair removal |
EP1482848A4 (en) * | 2002-03-12 | 2007-08-15 | Palomar Medical Tech Inc | Method and apparatus for hair growth management |
US7322972B2 (en) * | 2002-04-10 | 2008-01-29 | The Regents Of The University Of California | In vivo port wine stain, burn and melanin depth determination using a photoacoustic probe |
DE102009048801B4 (en) | 2009-10-08 | 2022-06-23 | Andreas Stihl Ag & Co. Kg | Spark plug connector and arrangement of a spark plug and a spark plug connector |
-
2002
- 2002-02-06 US US10/072,610 patent/US7141049B2/en not_active Expired - Lifetime
-
2003
- 2003-02-05 ES ES03706097T patent/ES2314180T3/en not_active Expired - Lifetime
- 2003-02-05 WO PCT/US2003/003507 patent/WO2003065916A1/en active Application Filing
- 2003-02-05 CN CNA038034026A patent/CN1627923A/en active Pending
- 2003-02-05 AT AT03706097T patent/ATE411778T1/en not_active IP Right Cessation
- 2003-02-05 EP EP03706097A patent/EP1471845B1/en not_active Expired - Lifetime
- 2003-02-05 BR BR0307392-0A patent/BR0307392A/en not_active IP Right Cessation
- 2003-02-05 KR KR1020047012078A patent/KR100706155B1/en active IP Right Grant
- 2003-02-05 JP JP2003565346A patent/JP2005516666A/en active Pending
- 2003-02-05 EP EP07008905A patent/EP1808145A2/en not_active Withdrawn
- 2003-02-05 CA CA002474421A patent/CA2474421A1/en not_active Abandoned
- 2003-02-05 DE DE60324249T patent/DE60324249D1/en not_active Expired - Lifetime
- 2003-02-05 AU AU2003207858A patent/AU2003207858B2/en not_active Expired
-
2006
- 2006-09-12 US US11/531,081 patent/US20070010811A1/en not_active Abandoned
-
2009
- 2009-07-22 US US12/507,405 patent/US8603088B2/en not_active Expired - Lifetime
-
2013
- 2013-11-08 US US14/074,927 patent/US9636175B2/en not_active Expired - Fee Related
-
2017
- 2017-04-10 US US15/483,556 patent/US20170209212A1/en not_active Abandoned
-
2018
- 2018-11-20 US US16/196,114 patent/US20190090947A1/en not_active Abandoned
Patent Citations (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3327712A (en) * | 1961-09-15 | 1967-06-27 | Ira H Kaufman | Photocoagulation type fiber optical surgical device |
US3658051A (en) * | 1967-11-13 | 1972-04-25 | Kenneth Sheldon Maclean | Method of treating living things using high intensity pulsed magnetic field |
US3818129A (en) * | 1971-06-30 | 1974-06-18 | Hitachi Ltd | Laser imaging device |
US3800802A (en) * | 1972-01-07 | 1974-04-02 | Int Medical Electronics Ltd | Short-wave therapy apparatus |
US3930504A (en) * | 1973-12-12 | 1976-01-06 | Clinitex, Inc. | Portable light coagulator |
US4315503A (en) * | 1976-11-17 | 1982-02-16 | Electro-Biology, Inc. | Modification of the growth, repair and maintenance behavior of living tissues and cells by a specific and selective change in electrical environment |
US4093975A (en) * | 1977-01-05 | 1978-06-06 | Roberts Wallace A | High-voltage apparatus for skin therapy |
US4140130A (en) * | 1977-05-31 | 1979-02-20 | Storm Iii Frederick K | Electrode structure for radio frequency localized heating of tumor bearing tissue |
US4321930A (en) * | 1977-06-28 | 1982-03-30 | Duke University, Inc. | Apparatus for monitoring metabolism in body organs |
US4380240A (en) * | 1977-06-28 | 1983-04-19 | Duke University, Inc. | Apparatus for monitoring metabolism in body organs |
US4186729A (en) * | 1977-11-25 | 1980-02-05 | Donald L. Morton & Associates | Deep heating electrode |
US4316474A (en) * | 1979-08-17 | 1982-02-23 | Firma Electric Electronic Service Jens Spethmann | High frequency radiation therapy apparatus |
US5097844A (en) * | 1980-04-02 | 1992-03-24 | Bsd Medical Corporation | Hyperthermia apparatus having three-dimensional focusing |
US4589423A (en) * | 1980-04-02 | 1986-05-20 | Bsd Medical Corporation | Apparatus for creating hyperthermia in tissue |
US4506196A (en) * | 1980-11-13 | 1985-03-19 | Candela Corporation | Series inverter for capacitor charging |
US4647830A (en) * | 1980-11-13 | 1987-03-03 | Candela Corporation | Series inverter circuit with timing responsive to reflective current |
US4444190A (en) * | 1980-11-24 | 1984-04-24 | Mutzhas Maximilian F | Device for the phototherapeutic treatment of hyperbilirubinemia |
US4388924A (en) * | 1981-05-21 | 1983-06-21 | Weissman Howard R | Method for laser depilation |
US4564011A (en) * | 1982-03-22 | 1986-01-14 | Leon Goldman | Laser optic device and method |
US4522210A (en) * | 1982-04-02 | 1985-06-11 | Philippe Simonin | Method of skin treatment and device for carrying out the said method |
US4645980A (en) * | 1982-08-11 | 1987-02-24 | Yang Tai Her | Lighting system having photosensing timing switch circuit |
US4671286A (en) * | 1983-03-04 | 1987-06-09 | Compagnie Francaise d'Electronique Medicale International SA (C.O.F.R.E.M. International SA) | RF therapy apparatus |
US4497018A (en) * | 1983-05-05 | 1985-01-29 | Candela Corporation | Series inverter for capacitor charging |
US4672969A (en) * | 1983-10-06 | 1987-06-16 | Sonomo Corporation | Laser healing method |
US4653495A (en) * | 1984-01-13 | 1987-03-31 | Kabushiki Kaisha Toshiba | Laser medical apparatus |
US4798215A (en) * | 1984-03-15 | 1989-01-17 | Bsd Medical Corporation | Hyperthermia apparatus |
US4810658A (en) * | 1984-06-13 | 1989-03-07 | Ares-Serono Research & Development | Photometric instruments, their use in methods of optical analysis, and ancillary devices therefor |
US4733660A (en) * | 1984-08-07 | 1988-03-29 | Medical Laser Research And Development Corporation | Laser system for providing target specific energy deposition and damage |
US4829262A (en) * | 1984-10-25 | 1989-05-09 | Candela Laser Corporation | Long pulse tunable light amplifier |
US4726377A (en) * | 1985-05-02 | 1988-02-23 | Jegers Viktor J | Modular control for tanning beds |
US4729375A (en) * | 1985-05-02 | 1988-03-08 | Sun Time, Inc. | Modular control for tanning beds |
US4835749A (en) * | 1985-09-11 | 1989-05-30 | Welton Truett T | Safe tanning lamp control system |
US5618284A (en) * | 1985-09-27 | 1997-04-08 | Sunrise Technologies | Collagen treatment apparatus |
US5484432A (en) * | 1985-09-27 | 1996-01-16 | Laser Biotech, Inc. | Collagen treatment apparatus |
US4901720A (en) * | 1986-04-08 | 1990-02-20 | C. R. Bard, Inc. | Power control for beam-type electrosurgical unit |
US5085227A (en) * | 1989-02-15 | 1992-02-04 | Gerard Ramon | Conductive cutaneous coating for applying electric currents for therapeutic or beauty treatment |
US5008579A (en) * | 1989-03-03 | 1991-04-16 | E. F. Johnson Co. | Light emitting polymer electrical energy source |
US5282797A (en) * | 1989-05-30 | 1994-02-01 | Cyrus Chess | Method for treating cutaneous vascular lesions |
US5011483A (en) * | 1989-06-26 | 1991-04-30 | Dennis Sleister | Combined electrosurgery and laser beam delivery device |
US5012816A (en) * | 1989-08-31 | 1991-05-07 | Gabor Lederer | Electronic acupuncture device |
US5312395A (en) * | 1990-03-14 | 1994-05-17 | Boston University | Method of treating pigmented lesions using pulsed irradiation |
US5113462A (en) * | 1990-06-01 | 1992-05-12 | Candela Laser Corporation | High energy fiber optica coupler |
US5083093A (en) * | 1990-06-22 | 1992-01-21 | Varian Associates, Inc. | Circuit for coupling energy to pulse forming network or capacitor |
US5186181A (en) * | 1990-07-27 | 1993-02-16 | Cafiero Franconi | Radio frequency thermotherapy |
US5290273A (en) * | 1991-08-12 | 1994-03-01 | Tan Oon T | Laser treatment method for removing pigement containing lesions from the skin of a living human |
US5400791A (en) * | 1991-10-11 | 1995-03-28 | Candela Laser Corporation | Infrared fundus video angiography system |
US5383874A (en) * | 1991-11-08 | 1995-01-24 | Ep Technologies, Inc. | Systems for identifying catheters and monitoring their use |
USRE36634E (en) * | 1991-12-12 | 2000-03-28 | Ghaffari; Shahriar | Optical system for treatment of vascular lesions |
US5281798A (en) * | 1991-12-24 | 1994-01-25 | Maxwell Laboratories, Inc. | Method and system for selective removal of material coating from a substrate using a flashlamp |
US5194723A (en) * | 1991-12-24 | 1993-03-16 | Maxwell Laboratories, Inc. | Photoacoustic control of a pulsed light material removal process |
US5290274A (en) * | 1992-06-16 | 1994-03-01 | Laser Medical Technology, Inc. | Laser apparatus for medical and dental treatments |
US5401272A (en) * | 1992-09-25 | 1995-03-28 | Envision Surgical Systems, Inc. | Multimodality probe with extendable bipolar electrodes |
US5720772A (en) * | 1992-10-20 | 1998-02-24 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US6514243B1 (en) * | 1992-10-20 | 2003-02-04 | Lumenis Ltd. | Method and apparatus for electromagnetic treatment of the skin, including hair depilation |
US6174325B1 (en) * | 1992-10-20 | 2001-01-16 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5755751A (en) * | 1992-10-20 | 1998-05-26 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5405368A (en) * | 1992-10-20 | 1995-04-11 | Esc Inc. | Method and apparatus for therapeutic electromagnetic treatment |
US5620478A (en) * | 1992-10-20 | 1997-04-15 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5626631A (en) * | 1992-10-20 | 1997-05-06 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US6171332B1 (en) * | 1992-10-23 | 2001-01-09 | Photo Therapeutics Limited | Light source |
US5707403A (en) * | 1993-02-24 | 1998-01-13 | Star Medical Technologies, Inc. | Method for the laser treatment of subsurface blood vessels |
US5396887A (en) * | 1993-09-23 | 1995-03-14 | Cardiac Pathways Corporation | Apparatus and method for detecting contact pressure |
US5723803A (en) * | 1993-09-30 | 1998-03-03 | Yamaha Corporation | Automatic performance apparatus |
US5507790A (en) * | 1994-03-21 | 1996-04-16 | Weiss; William V. | Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism |
US5489279A (en) * | 1994-03-21 | 1996-02-06 | Dusa Pharmaceuticals, Inc. | Method of applying photodynamic therapy to dermal lesion |
US5728141A (en) * | 1994-05-04 | 1998-03-17 | Indiba, S.A. | Electrotherapy apparatus |
US5509916A (en) * | 1994-08-12 | 1996-04-23 | Valleylab Inc. | Laser-assisted electrosurgery system |
US5514130A (en) * | 1994-10-11 | 1996-05-07 | Dorsal Med International | RF apparatus for controlled depth ablation of soft tissue |
US5735844A (en) * | 1995-02-01 | 1998-04-07 | The General Hospital Corporation | Hair removal using optical pulses |
US5595568A (en) * | 1995-02-01 | 1997-01-21 | The General Hospital Corporation | Permanent hair removal using optical pulses |
US5885273A (en) * | 1995-03-29 | 1999-03-23 | Esc Medical Systems, Ltd. | Method for depilation using pulsed electromagnetic radiation |
US6377854B1 (en) * | 1995-05-05 | 2002-04-23 | Thermage, Inc. | Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers |
US6377855B1 (en) * | 1995-05-05 | 2002-04-23 | Thermage, Inc. | Method and apparatus for controlled contraction of collagen tissue |
US6387380B1 (en) * | 1995-05-05 | 2002-05-14 | Thermage, Inc. | Apparatus for controlled contraction of collagen tissue |
US6381498B1 (en) * | 1995-05-05 | 2002-04-30 | Thermage, Inc. | Method and apparatus for controlled contraction of collagen tissue |
US5755753A (en) * | 1995-05-05 | 1998-05-26 | Thermage, Inc. | Method for controlled contraction of collagen tissue |
US6381497B1 (en) * | 1995-05-05 | 2002-04-30 | Thermage, Inc. | Method for smoothing contour irregularity of skin surface by controlled contraction of collagen tissue |
US5725565A (en) * | 1995-12-04 | 1998-03-10 | Smith; Daniel E. | Tanning bed safety device |
US20040034346A1 (en) * | 1996-01-05 | 2004-02-19 | Stern Roger A. | RF device with thermo-electric cooler |
US20040002704A1 (en) * | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Treatment apparatus with electromagnetic energy delivery device and non-volatile memory |
US6350276B1 (en) * | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
US20040002705A1 (en) * | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US20040030332A1 (en) * | 1996-01-05 | 2004-02-12 | Knowlton Edward W. | Handpiece with electrode and non-volatile memory |
US20040000316A1 (en) * | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US6214034B1 (en) * | 1996-09-04 | 2001-04-10 | Radiancy, Inc. | Method of selective photothermolysis |
US6053910A (en) * | 1996-10-30 | 2000-04-25 | Megadyne Medical Products, Inc. | Capacitive reusable electrosurgical return electrode |
US6544258B2 (en) * | 1996-10-30 | 2003-04-08 | Mega-Dyne Medical Products, Inc. | Pressure sore pad having self-limiting electrosurgical return electrode properties and optional heating/cooling capabilities |
US6009876A (en) * | 1997-05-20 | 2000-01-04 | Yavitz; Edward Q. | Method for modifying and reshaping collagen beneath the surface of skin |
US6014579A (en) * | 1997-07-21 | 2000-01-11 | Cardiac Pathways Corp. | Endocardial mapping catheter with movable electrode |
US6533781B2 (en) * | 1997-12-23 | 2003-03-18 | Team Medical Llc | Electrosurgical instrument |
US6047215A (en) * | 1998-03-06 | 2000-04-04 | Sonique Surgical Systems, Inc. | Method and apparatus for electromagnetically assisted liposuction |
US6053909A (en) * | 1998-03-27 | 2000-04-25 | Shadduck; John H. | Ionothermal delivery system and technique for medical procedures |
US7022121B2 (en) * | 1999-03-09 | 2006-04-04 | Thermage, Inc. | Handpiece for treatment of tissue |
US6690976B2 (en) * | 2000-04-13 | 2004-02-10 | Celsion Corporation | Thermotherapy method for treatment and prevention of breast cancer and cancer in other organs |
US6702808B1 (en) * | 2000-09-28 | 2004-03-09 | Syneron Medical Ltd. | Device and method for treating skin |
US6997923B2 (en) * | 2000-12-28 | 2006-02-14 | Palomar Medical Technologies, Inc. | Method and apparatus for EMR treatment |
US6567262B2 (en) * | 2001-06-01 | 2003-05-20 | Active Cool Ltd. | Liquid cooled TEC based system and method for cooling heat sensitive elements |
US6684107B1 (en) * | 2001-08-01 | 2004-01-27 | Voyager Medical Corporation | Wrinkle-reducing system |
US6981970B2 (en) * | 2002-12-16 | 2006-01-03 | Msq (M2) Ltd. | Device and method for treating skin |
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US20110046615A1 (en) * | 2004-04-01 | 2011-02-24 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
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US20080009923A1 (en) * | 2006-06-14 | 2008-01-10 | Paithankar Dilip Y | Treatment of Skin by Spatial Modulation of Thermal Heating |
US9486285B2 (en) | 2006-06-14 | 2016-11-08 | Candela Corporation | Treatment of skin by spatial modulation of thermal heating |
US8246611B2 (en) | 2006-06-14 | 2012-08-21 | Candela Corporation | Treatment of skin by spatial modulation of thermal heating |
US10292859B2 (en) | 2006-09-26 | 2019-05-21 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US11219549B2 (en) | 2006-09-26 | 2022-01-11 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
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US20080077201A1 (en) * | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
US11395760B2 (en) | 2006-09-26 | 2022-07-26 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US9375345B2 (en) | 2006-09-26 | 2016-06-28 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US9427285B2 (en) | 2007-04-19 | 2016-08-30 | Miramar Labs, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
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US20080269734A1 (en) * | 2007-04-26 | 2008-10-30 | Agustina Vila Echague | Optical Array for Treating Biological Tissue |
US20080269735A1 (en) * | 2007-04-26 | 2008-10-30 | Agustina Vila Echague | Optical array for treating biological tissue |
US10383787B2 (en) | 2007-05-18 | 2019-08-20 | Zeltiq Aesthetics, Inc. | Treatment apparatus for removing heat from subcutaneous lipid-rich cells and massaging tissue |
US11291606B2 (en) | 2007-05-18 | 2022-04-05 | Zeltiq Aesthetics, Inc. | Treatment apparatus for removing heat from subcutaneous lipid-rich cells and massaging tissue |
US20080306418A1 (en) * | 2007-06-05 | 2008-12-11 | Reliant Technologies, Inc. | Method for Reducing Pain of Dermatological Treatments |
US9364287B2 (en) | 2007-06-05 | 2016-06-14 | Reliant Technologies, Inc. | Method for reducing pain of dermatological treatments |
US9655770B2 (en) | 2007-07-13 | 2017-05-23 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
US20090043301A1 (en) * | 2007-08-09 | 2009-02-12 | Asthmatx, Inc. | Monopolar energy delivery devices and methods for controlling current density in tissue |
US10675178B2 (en) | 2007-08-21 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
US11583438B1 (en) | 2007-08-21 | 2023-02-21 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
US9408745B2 (en) | 2007-08-21 | 2016-08-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
US8406894B2 (en) | 2007-12-12 | 2013-03-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US20090281540A1 (en) * | 2008-05-06 | 2009-11-12 | Blomgren Richard D | Apparatus, Systems and Methods for Treating a Human Tissue Condition |
US8348938B2 (en) | 2008-05-06 | 2013-01-08 | Old Dominian University Research Foundation | Apparatus, systems and methods for treating a human tissue condition |
US9737434B2 (en) | 2008-12-17 | 2017-08-22 | Zeltiq Aestehtics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
US8882758B2 (en) | 2009-01-09 | 2014-11-11 | Solta Medical, Inc. | Tissue treatment apparatus and systems with pain mitigation and methods for mitigating pain during tissue treatments |
US8506506B2 (en) | 2009-01-12 | 2013-08-13 | Solta Medical, Inc. | Tissue treatment apparatus with functional mechanical stimulation and methods for reducing pain during tissue treatments |
US20100179455A1 (en) * | 2009-01-12 | 2010-07-15 | Solta Medical, Inc. | Tissue treatment apparatus with functional mechanical stimulation and methods for reducing pain during tissue treatments |
US9861520B2 (en) | 2009-04-30 | 2018-01-09 | Zeltiq Aesthetics, Inc. | Device, system and method of removing heat from subcutaneous lipid-rich cells |
US20100280582A1 (en) * | 2009-04-30 | 2010-11-04 | Zeltiq Aesthetics, Inc. | Device, system and method of removing heat from subcutaneous lipid-rich cells |
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US8788060B2 (en) | 2009-07-16 | 2014-07-22 | Solta Medical, Inc. | Tissue treatment systems with high powered functional electrical stimulation and methods for reducing pain during tissue treatments |
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US9636175B2 (en) | 2017-05-02 |
AU2003207858B2 (en) | 2006-08-10 |
ATE411778T1 (en) | 2008-11-15 |
EP1471845B1 (en) | 2008-10-22 |
US20040111087A1 (en) | 2004-06-10 |
BR0307392A (en) | 2004-11-09 |
AU2003207858A1 (en) | 2003-09-02 |
KR20040093706A (en) | 2004-11-08 |
CA2474421A1 (en) | 2003-08-14 |
JP2005516666A (en) | 2005-06-09 |
DE60324249D1 (en) | 2008-12-04 |
US20170209212A1 (en) | 2017-07-27 |
US7141049B2 (en) | 2006-11-28 |
AU2003207858A2 (en) | 2003-09-02 |
EP1471845A1 (en) | 2004-11-03 |
EP1808145A2 (en) | 2007-07-18 |
WO2003065916A1 (en) | 2003-08-14 |
US20090287207A1 (en) | 2009-11-19 |
CN1627923A (en) | 2005-06-15 |
US20190090947A1 (en) | 2019-03-28 |
US20140066918A1 (en) | 2014-03-06 |
US8603088B2 (en) | 2013-12-10 |
KR100706155B1 (en) | 2007-04-11 |
ES2314180T3 (en) | 2009-03-16 |
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