US20060111744A1 - Method and system for treatment of sweat glands - Google Patents
Method and system for treatment of sweat glands Download PDFInfo
- Publication number
- US20060111744A1 US20060111744A1 US11/163,152 US16315205A US2006111744A1 US 20060111744 A1 US20060111744 A1 US 20060111744A1 US 16315205 A US16315205 A US 16315205A US 2006111744 A1 US2006111744 A1 US 2006111744A1
- Authority
- US
- United States
- Prior art keywords
- treatment
- ultrasound
- imaging
- transducer
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/42—Details of probe positioning or probe attachment to the patient
- A61B8/4272—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue
- A61B8/4281—Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue characterised by sound-transmitting media or devices for coupling the transducer to the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320069—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic for ablating tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0078—Ultrasound therapy with multiple treatment transducers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
Definitions
- This invention generally relates to a therapeutic ultrasound method and system, and more particularly, to a method and system for ultrasound treatment for superficial tissue containing sweat glands.
- the sweat glands in the body are of divided into apocrine and eccrine glands.
- Apocrine glands are similar to sebaceous glands, and are present mainly in the axillae. These glands, like sebaceous glands, secrete an oily proteinaceous product into the follicles. Bacterial digestion of apocrine sweat is largely responsible for underarm “body odor”.
- eccrine sweat glands are present deep in the dermis in the palms, soles and armpits and are responsible for temperature regulation resulting from sweating. Excessive activity of these glands also results in copious amounts of abnormal sweating (“hyperhidrosis”), primarily under autonomic neuronal control.
- the present invention describes a non-invasive method and system for using therapeutic ultrasound energy for the treatment of conditions resulting from sweat gland disorders.
- An ultrasound system and method comprises a transducer probe and control system configured to deliver ultrasound energy to the regions of the superficial tissue (e.g., skin) such that the energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
- the ultrasound transducer can be driven at a number of different frequency regimes such that the depth and shape of energy concentration can match the region of treatment.
- the ultrasound source or beam radiated from the transducer can be highly focused, weakly focused, or divergent, each in a cylindrical or spherical geometric configuration, and/or can also be planar to radiate a directive beam through the tissue, or various other configurations.
- the ultrasound field can be varied spatially and temporally in a suitable manner to achieve the optimal tissue effect and/or type of conformal lesion for treating the sweat glands.
- FIG. 1 illustrates a block diagram of an ultrasound therapy system for treating sweat glands in accordance with an exemplary embodiment of the present invention
- FIG. 2A-2E illustrates schematic diagrams of ultrasound treatment systems configured to treat the sweat glands via direct targeting of heating and damage within the treatment layer in accordance with various exemplary embodiments of the present invention
- FIGS. 3A and 3B illustrate block diagrams of an exemplary control system in accordance with exemplary embodiments of the present invention
- FIGS. 4A and 4B illustrate block diagrams of an exemplary probe system in accordance with exemplary embodiments of the present invention
- FIG. 5 illustrates a cross-sectional diagram of an exemplary transducer in accordance with an exemplary embodiment of the present invention
- FIGS. 6A and 6B illustrate cross-sectional diagrams of an exemplary transducer in accordance with exemplary embodiments of the present invention
- FIG. 7 illustrates exemplary transducer configurations for ultrasound treatment in accordance with various exemplary embodiments of the present invention
- FIGS. 8A and 8B illustrate cross-sectional diagrams of an exemplary transducer in accordance with another exemplary embodiment of the present invention
- FIG. 9 illustrates an exemplary transducer configured as a two-dimensional array for ultrasound treatment in accordance with an exemplary embodiment of the present invention
- FIGS. 10A-10F illustrate cross-sectional diagrams of exemplary transducers in accordance with other exemplary embodiments of the present invention.
- FIG. 11 illustrates a schematic diagram of an acoustic coupling and cooling system in accordance with an exemplary embodiment of the present invention
- FIG. 12 illustrates a block diagram of an ultrasound treatment system combined with additional subsystems and methods of treatment monitoring and/or treatment imaging as well as a secondary treatment subsystem in accordance with an exemplary embodiment of the present invention.
- FIG. 13 illustrates a schematic diagram with imaging, therapy, or monitoring being provided with one or more active or passive oral inserts in accordance with an exemplary embodiment of the present invention.
- the present invention may be described herein in terms of various components and processing steps. It should be appreciated that such components and steps may be realized by any number of hardware components configured to perform the specified functions.
- the present invention may be configured with various medical treatment devices, visual imaging and display devices, input terminals and the like, which may carry out a variety of functions under the control of one or more control systems or other control devices.
- the present invention may be practiced in any number of medical or treatment contexts and that the exemplary embodiments relating to a method and system for sweat gland treatment as described herein are merely a few of the exemplary applications for the invention.
- the principles, features and methods discussed may be applied to any medical or other tissue or treatment application.
- an ultrasound transducer probe and control system are configured to deliver ultrasound energy to a targeted/specified depth and zone where the sweat gland population is required to be treated.
- the ultrasound beam from the transducer probe can be spatially and/or temporally adjusted, modified or otherwise controlled to match the adequate treatment of the sweat glands in the region of interest.
- an exemplary treatment system 100 configured to treat a region of interest (ROI) 106 comprises a control system 102 , an imaging/therapy probe with acoustic coupling 104 , and a display system 108 .
- ROI region of interest
- Control system 102 and display 108 can comprise various configurations for controlling functionality of probe 104 and system 100 , including for example a microprocessor with software and a plurality of input/output and communication devices, a system for controlling electronic and/or mechanical scanning and/or multiplexing of transducers, a system for power delivery, systems for monitoring, systems for sensing the spatial parameters and/or temporal parameters of the probe and transducers, and/or systems for handling user input and recording treatment input and results, among others.
- Imaging/therapy probe 104 can comprise various probe and/or transducer configurations.
- probe 104 can be configured for a combined dual-mode imaging/therapy transducer, coupled or co-housed imaging/therapy transducers, a separate therapy probe and separate imaging probe, or a single therapy probe.
- imaging transducers may operate at frequencies from approximately 2 MHz to 75 MHz or more, while therapy energy can be delivered at frequencies from approximately 500 kHz to 15 MHz, with 2 MHz to 25 MHz being typical.
- sweat glands 230 are generally located within a dermis layer 214 at a depth close to hair bulbs 236 .
- an ultrasound transducer probe can be coupled to the skin tissue using one of the numerous coupling media, such as water, mineral oils, gels, and the like.
- an exemplary treatment method and system are configured for initially imaging a region 222 within a region of interest 206 and displaying that region 224 on a display 208 to facilitate localization of the treatment area and surrounding structures, e.g., identification of sweat glands 230 , such as within the axillary region (armpit), the palms and soles or any other tissue or skin surrounding sweat glands.
- localization e.g., delivery of ultrasound energy 220 at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect of thermal ablation to treat a sweat gland 230 is provided.
- monitoring of the treatment area and surrounding structures can be conducted to further planning and assessing of the results and/or providing feedback to control system 202 and a system operator.
- localization can be facilitated through ultrasound imaging that can be used to define the position of a sweat gland 230 and/or the depth of sweat glands 230 over a region of interest before depositing in a defined pattern at a target region 220 .
- ultrasound imaging can also be used for safety purposes, namely, to avoid injuring vital structures, such as nerve endings 240 .
- localization can also be accomplished without imaging region 222 , but instead can be based on prior known depths of sweat glands or other target regions, and thus be configured geometrically and/or electronically to selectively deposit energy at a particular known depth below skin surface 210 to a target region 220 .
- the ultrasound beam from probe 204 can be spatially and/or temporally controlled by changing the spatial parameters of the transducer, such as the placement, distance, treatment depth and transducer structure, as well as by changing the temporal parameters of transducer, such as the frequency, drive amplitude, and timing, with such control handled via control system 202 .
- the temporal energy exposure at one location may range from approximately to 40 ms to 40 seconds, while the corresponding source frequency can suitably range from approximately 500 kHz to 15 MHz.
- Such spatial and temporal parameters can also be suitably monitored and/or utilized in open-loop and/or closed-loop feedback systems within treatment system 200 .
- conformal lesions of various, specifically targeted, shapes, sizes and orientations can be configured within target region 220 .
- the treatment resulting from ultrasound energy delivery in the region of sweat glands 230 can be used to achieve selective ablation of regions of sub-epidermal region (0.5-10 mm diameter zones).
- one or more treated zones 242 can be configured to produce regions of ablative damage in spatially defined patterns, such as a discrete locus of spaced treatment spots or two- or three- dimensional matrix of damage or destroyed tissue, e.g., a matrix of cross-stitched, ellipsoidal/cigar-shaped, wedge-shaped, mushroom-shaped or any other conformal lesions, rather than heating and destroying the entire volume of the target layer of tissue.
- the surrounding undamaged tissue aids rapid healing and recovery.
- treatment system 200 could be configured to “carpet bomb” the fat layer at 1-7 mm depth, e.g., up to 90% of the sweat glands in the armpit can be ablated without any physiologic issues.
- an exemplary monitoring method may comprise monitoring the temperature profile or other tissue parameters of the region of interest 206 , such as attenuation, speed of sound, or mechanical properties such as stiffness and strain of the treatment region and suitably adjust the spatial and/or temporal characteristics and energy levels of the ultrasound therapy transducer of probe 204 .
- the results of such monitoring techniques may be indicated on display 208 by means of one-, two-, or three-dimensional images of monitoring results 250 , or may simply comprise a success or fail-type indicator 252 , or combinations thereof.
- Additional treatment monitoring techniques may be based on one or more of temperature, video, profilometry, and/or stiffness or strain gauges or any other suitable sensing technique.
- the non-thermal effects from an acoustic field can also “shock” the sweat producing apocrine and eccrine cells in to reduced activity.
- These effects mentioned here as examples are, but not limited to, acoustic cavitation, acoustic streaming, inter-cellular shear effects, cell resonant effects, and the like.
- focused or directive ultrasound energy can be used for the treatment of sweat glands in the armpit (without the combination of pharmacological formulations).
- a clinical indication would be to use in the management of Hidradenitis suppurativa .
- Ultrasound energy deposited at a selective depth can also be used in combination with a number of pharmaceutical formulations that are currently prescribed for the treatment of sweat gland hyperactivity in the axillary region, palms and soles.
- the ultrasound energy delivered to the target region in combination with the pharmaceutical agents such as BOTOX® or retinoids can help synergistically treat the sweat gland region by, (1) increasing activity of the agents due to the thermal and non-thermal mechanisms, (2) reduced requirement of overall drug dosage, as well as reducing the drug toxicity, (3) increase local effect of drug in a site selective manner.
- an exemplary control system 300 can be configured for coordination and control of the entire therapeutic treatment process to achieve the desired therapeutic effect of thermal ablation to treat a sweat gland.
- control system 300 can suitably comprise power source components 302 , sensing and monitoring components 304 , cooling and coupling controls 306 , and/or processing and control logic components 308 .
- Control system 300 can be configured and optimized in a variety of ways with more or less subsystems and components to implement the therapeutic system for controlled thermal injury of sweat glands, and the embodiments in FIGS. 3A and 3B are merely for illustration purposes.
- control system 300 can comprise one or more direct current (DC) power supplies 303 configured to provide electrical energy for entire control system 300 , including power required by a transducer electronic amplifier/driver 312 .
- a DC current sense device 305 can also be provided to confirm the level of power going into amplifiers/drivers 312 for safety and monitoring purposes.
- Amplifiers/drivers 312 can comprise multi-channel or single channel power amplifiers and/or drivers. In accordance with an exemplary embodiment for transducer array configurations, amplifiers/drivers 312 can also be configured with a beamformer to facilitate array focusing. An exemplary beamformer can be electrically excited by an oscillator/digitally controlled waveform synthesizer 310 with related switching logic.
- the power sourcing components can also include various filtering configurations 314 .
- switchable harmonic filters and/or matching may be used at the output of amplifier/driver 312 to increase the drive efficiency and effectiveness.
- Power detection components 316 may also be included to confirm appropriate operation and calibration. For example, electric power and other energy detection components 316 may be used to monitor the amount of power going to an exemplary probe system.
- sensing and monitoring components 304 may also be suitably implemented within control system 300 .
- monitoring, sensing and interface control components 324 may be configured to operate with various motion detection systems implemented within transducer probe 204 to receive and process information such as acoustic or other spatial and temporal information from a region of interest.
- Sensing and monitoring components can also include various controls, interfacing and switches 309 and/or power detectors 316 .
- Such sensing and monitoring components 304 can facilitate open-loop and/or closed-loop feedback systems within treatment system 200 .
- Cooling/coupling control systems 306 may be provided to remove waste heat from an exemplary probe 204 , provide a controlled temperature at the superficial tissue interface and deeper into tissue, and/or provide acoustic coupling from transducer probe 204 to region-of-interest 206 . Such cooling/coupling control systems 306 can also be configured to operate in both open-loop and/or closed-loop feedback arrangements with various coupling and feedback components.
- Processing and control logic components 308 can comprise various system processors and digital control logic 307 , such as one or more of microcontrollers, microprocessors, field-programmable gate arrays (FPGAs), computer boards, and associated components, including firmware and control software 326 , which interfaces to user controls and interfacing circuits as well as input/output circuits and systems for communications, displays, interfacing, storage, documentation, and other useful functions.
- System software and firmware 326 controls all initialization, timing, level setting, monitoring, safety monitoring, and all other system functions required to accomplish user-defined treatment objectives.
- various control switches 308 can also be suitably configured to control operation.
- transducer probe 204 can also be configured in various manners and comprise a number of reusable and/or disposable components and parts in various embodiments to facilitate its operation.
- transducer probe 204 can be configured within any type of transducer probe housing or arrangement for facilitating the coupling of transducer to a tissue interface, with such housing comprising various shapes, contours and configurations.
- Transducer probe 204 can comprise any type of matching, such as for example, electric matching, which may be electrically switchable; multiplexer circuits and/or aperture/element selection circuits; and/or probe identification devices, to certify probe handle, electric matching, transducer usage history and calibration, such as one or more serial EEPROM (memories).
- Transducer probe 204 may also comprise cables and connectors; motion mechanisms, motion sensors and encoders; thermal monitoring sensors; and/or user control and status related switches, and indicators such as LEDs.
- a motion mechanism in probe 204 may be used to controllably create multiple lesions, or sensing of probe motion itself may be used to controllably create multiple lesions and/or stop creation of lesions, e.g. for safety reasons if probe 204 is suddenly jerked or is dropped.
- an external motion encoder arm may be used to hold the probe during use, whereby the spatial position and attitude of probe 104 is sent to the control system to help controllably create lesions.
- other sensing functionality such as profilometers or other imaging modalities may be integrated into the probe in accordance with various exemplary embodiments.
- a transducer probe 400 can comprise a control interface 402 , a transducer 404 , coupling components 406 , and monitoring/sensing components 408 , and/or motion mechanism 410 .
- transducer probe 400 can be configured and optimized in a variety of ways with more or less parts and components to provide treatment of sweat glands, and the embodiments in FIGS. 4A and 4B are merely for illustration purposes.
- Control interface 402 is configured for interfacing with control system 300 to facilitate control of transducer probe 400 .
- Control interface components 402 can comprise multiplexer/aperture select 424 , switchable electric matching networks 426 , serial EEPROMs and/or other processing components and matching and probe usage information 430 and interface connectors 432 .
- Coupling components 406 can comprise various devices to facilitate coupling of transducer probe 400 to a region of interest.
- coupling components 406 can comprise cooling and acoustic coupling system 420 configured for acoustic coupling of ultrasound energy and signals.
- Acoustic cooling/coupling system 420 with possible connections such as manifolds may be utilized to couple sound into the region-of-interest, control temperature at the interface and deeper into tissue, provide liquid-filled lens focusing, and/or to remove transducer waste heat.
- Coupling system 420 may facilitate such coupling through use of various coupling mediums, including air and other gases, water and other fluids, gels, solids, and/or any combination thereof, or any other medium that allows for signals to be transmitted between transducer active elements 412 and a region of interest.
- coupling system 420 can also be configured for providing temperature control during the treatment application.
- coupling system 420 can be configured for controlled cooling of an interface surface or region between transducer probe 400 and a region of interest and beyond by suitably controlling the temperature of the coupling medium.
- the suitable temperature for such coupling medium can be achieved in various manners, and utilize various feedback systems, such as thermocouples, thermistors or any other device or system configured for temperature measurement of a coupling medium.
- Such controlled cooling can be configured to further facilitate spatial and/or thermal energy control of transducer probe 400 .
- acoustic coupling and cooling 1140 can be provided to acoustically couple energy and imaging signals from transducer probe 1104 to and from the region of interest 1106 and deeper into tissue, to provide thermal control at the probe to region-of-interest interface 1110 , and to remove potential waste heat from the transducer probe at region 1144 .
- Temperature monitoring can be provided at the coupling interface via a thermal sensor 1146 to provide a mechanism of temperature measurement 1148 and control via control system 1102 and a thermal control system 1142 .
- Thermal control may consist of passive cooling such as via heat sinks or natural conduction and convection or via active cooling such as with peltier thermoelectric coolers, refrigerants, or fluid-based systems comprised of pump, fluid reservoir, bubble detection, flow sensor, flow channels/tubing 1144 and thermal control 1142 .
- monitoring and sensing components 408 can comprise various motion and/or position sensors 416 , temperature monitoring sensors 418 , user control and feedback switches 414 and other like components for facilitating control by control system 300 , e.g., to facilitate spatial and/or temporal control through open-loop and closed-loop feedback arrangements that monitor various spatial and temporal characteristics.
- Motion mechanism 410 can comprise manual operation, mechanical arrangements, or some combination thereof.
- a motion mechanism 422 can be suitably controlled by control system 300 , such as through the use of accelerometers, encoders or other position/orientation devices 416 to determine and enable movement and positions of transducer probe 400 .
- Linear, rotational or variable movement can be facilitated, e.g., those depending on the treatment application and tissue contour surface.
- Transducer 404 can comprise one or more transducers configured for treating of sweat glands and targeted regions. Transducer 404 can also comprise one or more transduction elements and/or lenses 412 .
- the transduction elements can comprise a piezoelectrically active material, such as lead zirconante titanate (PZT), or any other piezoelectrically active material, such as a piezoelectric ceramic, crystal, plastic, and/or composite materials, as well as lithium niobate, lead titanate, barium titanate, and/or lead metaniobate.
- PZT lead zirconante titanate
- transducer 404 can comprise any other materials configured for generating radiation and/or acoustical energy.
- Transducer 404 can also comprise one or more matching layers configured along with the transduction element such as coupled to the piezoelectrically active material. Acoustic matching layers and/or damping may be employed as necessary to achieve the desired electroacoustic response.
- the thickness of the transduction element of transducer 404 can be configured to be uniform. That is, a transduction element 412 can be configured to have a thickness that is substantially the same throughout. In accordance with another exemplary embodiment, the thickness of a transduction element 412 can also be configured to be variable. For example, transduction element(s) 412 of transducer 404 can be configured to have a first thickness selected to provide a center operating frequency of approximately 2 kHz to 75 MHz, such as for imaging applications. Transduction element 412 can also be configured with a second thickness selected to provide a center operating frequency of approximately 2 to 50 MHz, and typically between 2 MHz and 25 MHz for therapy application.
- Transducer 404 can be configured as a single broadband transducer excited with at least two or more frequencies to provide an adequate output for generating a desired response. Transducer 404 can also be configured as two or more individual transducers, wherein each transducer comprises one or more transduction element. The thickness of the transduction elements can be configured to provide center-operating frequencies in a desired treatment range.
- Transducer 404 may be composed of one or more individual transducers in any combination of focused, planar, or unfocused single-element, multi-element, or array transducers, including 1-D, 2-D, and annular arrays; linear, curvilinear, sector, or spherical arrays; spherically, cylindrically, and/or electronically focused, defocused, and/or lensed sources.
- transducer 500 can be configured as an acoustic array to facilitate phase focusing. That is, transducer 500 can be configured as an array of electronic apertures that may be operated by a variety of phases via variable electronic time delays.
- the electronic apertures of transducer 500 may be manipulated, driven, used, and/or configured to produce and/or deliver an energy beam corresponding to the phase variation caused by the electronic time delay.
- these phase variations can be used to deliver defocused beams, planar beams, and/or focused beams, each of which may be used in combination to achieve different physiological effects in a region of interest 510 .
- Transducer 500 may additionally comprise any software and/or other hardware for generating, producing and or driving a phased aperture array with one or more electronic time delays.
- Transducer 500 can also be configured to provide focused treatment to one or more regions of interest using various frequencies.
- transducer 500 can be configured with one or more variable depth devices to facilitate treatment.
- transducer 500 may be configured with variable depth devices disclosed in U.S. patent application Ser. No. 10/944,500, entitled “System and Method for Variable Depth Ultrasound”, filed on Sep. 16, 2004, having at least one common inventor and a common Assignee as the present application, and incorporated herein by reference.
- transducer 500 can also be configured to treat one or more additional ROI 510 through the enabling of sub-harmonics or pulse-echo imaging, as disclosed in U.S. patent application Ser. No. 10/944,499, entitled “Method and System for Ultrasound Treatment with a Multi-directional Transducer”, filed on Sep. 16, 2004, having at least one common inventor and a common Assignee as the present application, and also incorporated herein by reference.
- transducer 600 may also be configured with an electronic focusing array 604 in combination with one or more transduction elements 606 to facilitate increased flexibility in treating ROI 610 .
- Array 604 may be configured in a manner similar to transducer 502 . That is, array 604 can be configured as an array of electronic apertures that may be operated by a variety of phases via variable electronic time delays, for example, T 1 , T 2 . . . T j .
- the electronic apertures of array 604 may be manipulated, driven, used, and/or configured to produce and/or deliver energy in a manner corresponding to the phase variation caused by the electronic time delay.
- these phase variations can be used to deliver defocused beams, planar beams, and/or focused beams, each of which may be used in combination to achieve different physiological effects in ROI 610 .
- Transduction elements 606 may be configured to be concave, convex, and/or planar.
- transduction elements 606 A are configured to be concave in order to provide focused energy for treatment of ROI 610 . Additional embodiments are disclosed in U.S. patent application Ser. No. 10/944,500, entitled “Variable Depth Transducer System and Method”, and again incorporated herein by reference.
- transduction elements 606 B can be configured to be substantially flat in order to provide substantially uniform energy to ROI 610 .
- transduction elements 604 can be configured to be any combination of concave, convex, and/or substantially flat structures.
- a first transduction element can be configured to be concave
- a second transduction element can be configured to be substantially flat.
- transducer 404 can be configured as single-element arrays, wherein a single-element 802 , e.g., a transduction element of various structures and materials, can be configured with a plurality of masks 804 , such masks comprising ceramic, metal or any other material or structure for masking or altering energy distribution from element 802 , creating an array of energy distributions 808 .
- Masks 804 can be coupled directly to element 802 or separated by a standoff 806 , such as any suitably solid or liquid material.
- An exemplary transducer 404 can also be configured as an annular array to provide planar, focused and/or defocused acoustical energy.
- an annular array 1000 can comprise a plurality of rings 1012 , 1014 , 1016 to N. Rings 1012 , 1014 , 1016 to N can be mechanically and electrically isolated into a set of individual elements, and can create planar, focused, or defocused waves. For example, such waves can be centered on-axis, such as by methods of adjusting corresponding transmit and/or receive delays, ⁇ 1 , ⁇ 2 , ⁇ 3 . . . ⁇ N .
- An electronic focus can be suitably moved along various depth positions, and can enable variable strength or beam tightness, while an electronic defocus can have varying amounts of defocusing.
- a lens and/or convex or concave shaped annular array 1000 can also be provided to aid focusing or defocusing such that any time differential delays can be reduced. Movement of annular array 800 in one, two or three-dimensions, or along any path, such as through use of probes and/or any conventional robotic arm mechanisms, may be implemented to scan and/or treat a volume or any corresponding space within a region of interest.
- Transducer 404 can also be configured in other annular or non-array configurations for imaging/therapy functions.
- a transducer can comprise an imaging element 1012 configured with therapy element(s) 1014 .
- Elements 1012 and 1014 can comprise a single-transduction element, e.g., a combined imaging/transducer element, or separate elements, can be electrically isolated 1022 within the same transduction element or between separate imaging and therapy elements, and/or can comprise standoff 1024 or other matching layers, or any combination thereof.
- a transducer can comprise an imaging element 1012 having a surface 1028 configured for focusing, defocusing or planar energy distribution, with therapy elements 1014 including a stepped-configuration lens configured for focusing, defocusing, or planar energy distribution.
- transducer 404 may be configured to provide one, two and/or three-dimensional treatment applications for focusing acoustic energy to one or more regions of interest.
- transducer 404 can be suitably diced to form a one-dimensional array, e.g., transducer 602 comprising a single array of sub-transduction elements.
- transducer 404 may be suitably diced in two-dimensions to form a two-dimensional array.
- an exemplary two-dimensional array 900 can be suitably diced into a plurality of two-dimensional portions 902 .
- Two-dimensional portions 902 can be suitably configured to focus on the treatment region at a certain depth, and thus provide respective slices 904 of the treatment region.
- the two-dimensional array 900 can provide a two-dimensional slicing of the image place of a treatment region, thus providing two-dimensional treatment.
- transducer 404 may be suitably configured to provide three-dimensional treatment.
- a three-dimensional system can comprise a transducer within probe 104 configured with an adaptive algorithm, such as, for example, one utilizing three-dimensional graphic software, contained in a control system, such as control system 102 .
- the adaptive algorithm is suitably configured to receive two-dimensional imaging, temperature and/or treatment or other tissue parameter information relating to the region of interest, process the received information, and then provide corresponding three-dimensional imaging, temperature and/or treatment information.
- an exemplary three-dimensional system can comprise a two-dimensional array 900 configured with an adaptive algorithm to suitably receive 904 slices from different image planes of the treatment region, process the received information, and then provide volumetric information 906 , e.g., three-dimensional imaging, temperature and/or treatment information. Moreover, after processing the received information with the adaptive algorithm, the two-dimensional array 900 may suitably provide therapeutic heating to the volumetric region 906 as desired.
- an exemplary three-dimensional system can comprise a single transducer 404 configured within a probe arrangement to operate from various rotational and/or translational positions relative to a target region.
- ultrasound therapy transducer 700 can be configured for a single focus, an array of foci, a locus of foci, a line focus, and/or diffraction patterns.
- Transducer 700 can also comprise single elements, multiple elements, annular arrays, one-, two-, or three-dimensional arrays, broadband transducers, and/or combinations thereof, with or without lenses, acoustic components, and mechanical and/or electronic focusing.
- Transducers configured as spherically focused single elements 702 , annular arrays 704 , annular arrays with damped regions 706 , line focused single elements 708 , 1-D linear arrays 710 , 1-D curvilinear arrays in concave or convex form, with or without elevation focusing, 2-D arrays, and 3-D spatial arrangements of transducers may be used to perform therapy and/or imaging and acoustic monitoring functions.
- focusing and/or defocusing may be in one plane or two planes via mechanical focus 720 , convex lens 722 , concave lens 724 , compound or multiple lenses 726 , planar form 728 , or stepped form, such as illustrated in FIG. 10F .
- any transducer or combination of transducers may be utilized for treatment.
- an annular transducer may be used with an outer portion dedicated to therapy and the inner disk dedicated to broadband imaging wherein such imaging transducer and therapy transducer have different acoustic lenses and design, such as illustrated in FIG. 10C-10F .
- transduction elements 700 may comprise a piezoelectrically active material, such as lead zirconante titanate (PZT), or any other piezoelectrically active material, such as a piezoelectric ceramic, crystal, plastic, and/or composite materials, as well as lithium niobate, lead titanate, barium titanate, and/or lead metaniobate.
- Transduction elements 700 may also comprise one or more matching layers configured along with the piezoelectrically active material.
- transduction elements 700 can comprise any other materials configured for generating radiation and/or acoustical energy. A means of transferring energy to and from the transducer to the region of interest is provided.
- an exemplary treatment system 200 can be configured with and/or combined with various auxiliary systems to provide additional functions.
- an exemplary treatment system 1200 for treatment of sweat glands can further comprise an auxiliary imaging modality 1272 and/or auxiliary monitoring modality 1274 may be based upon at least one of photography and other visual optical methods, magnetic resonance imaging (MRI), computed tomography (CT), optical coherence tomography (OCT), electromagnetic, microwave, or radio frequency (RF) methods, positron emission tomography (PET), infrared, ultrasound, acoustic, or any other suitable method of visualization, localization, or monitoring of the region-of-interest, including imaging/monitoring enhancements.
- MRI magnetic resonance imaging
- CT computed tomography
- OCT optical coherence tomography
- RF radio frequency
- Such imaging/monitoring enhancement for ultrasound imaging via probe 1204 and control system 1202 can comprise M-mode, persistence, filtering, color, Doppler, and harmonic imaging among others; furthermore an ultrasound treatment system 1270 , as a primary source of treatment, may be combined with a secondary source of treatment 1276 , including radio frequency (RF), intense pulsed light (IPL), laser, infrared laser, microwave, or any other suitable energy source.
- RF radio frequency
- IPL intense pulsed light
- laser infrared laser
- microwave or any other suitable energy source.
- treatment composed of imaging, monitoring, and/or therapy to a region of interest 1302 and/or 1308 may be aided, augmented, and/or delivered with passive or active devices 1304 and/or 1306 within the oral and/or nasal cavity, respectively.
- passive or active device 1304 and/or 1306 are second transducers or acoustic reflectors acoustically coupled to the mucous membranes it is possible to obtain through transmission, tomographic, or round-trip acoustic waves which are useful for treatment monitoring, such as in measuring acoustic speed of sound and attenuation, which are temperature dependent; furthermore such transducers could be used to treat and/or image.
- an active, passive, or active/passive object 1304 and/or 1306 may be used to flatten the skin, and/or may be used as an imaging grid, marker, or beacon, to aid determination of position.
- a passive or active device 1304 and/or 1306 may also be used to aid cooling or temperature control.
- Natural air in the oral cavity and/or nasal cavity may also be used as passive device 1304 and/or 1306 whereby it may be utilized to as an acoustic reflector to aid thickness measurement and monitoring function.
- the present invention may be described herein in terms of various functional components and processing steps. It should be appreciated that such components and steps may be realized by any number of hardware components configured to perform the specified functions.
- the present invention may employ various medical treatment devices, visual imaging and display devices, input terminals and the like, which may carry out a variety of functions under the control of one or more control systems or other control devices.
- the present invention may be practiced in any number of medical contexts and that the exemplary embodiments relating to a system as described herein are merely indicative of exemplary applications for the invention.
- the principles, features and methods discussed may be applied to any medical application.
- various aspects of the present invention may be suitably applied to other applications, such as other medical or industrial applications.
Abstract
A method and system for ultrasound treatment of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
Description
- Application claims priority to and benefit of U.S. Provisional Application No. 60/61 7,752, entitled “Method and System for Treatment of Sweat Glands”, and filed on Oct. 6, 2004.
- This invention generally relates to a therapeutic ultrasound method and system, and more particularly, to a method and system for ultrasound treatment for superficial tissue containing sweat glands.
- The sweat glands in the body are of divided into apocrine and eccrine glands. Apocrine glands are similar to sebaceous glands, and are present mainly in the axillae. These glands, like sebaceous glands, secrete an oily proteinaceous product into the follicles. Bacterial digestion of apocrine sweat is largely responsible for underarm “body odor”. Similarly, eccrine sweat glands are present deep in the dermis in the palms, soles and armpits and are responsible for temperature regulation resulting from sweating. Excessive activity of these glands also results in copious amounts of abnormal sweating (“hyperhidrosis”), primarily under autonomic neuronal control. Reduction of sweating from under the armpits and other regions is a particularly desirable effect within the modern society. Presently, chemical antiperspirants and deodorants are used frequently as a matter of personal hygiene. Antiperspirants are aluminum based salts that block the sweat gland ducts. The deodorant changes the pH of the skin milieu thereby minimizing the presence of (smell inducing) bacteria. The effects with both these components however, are temporary and these chemicals are known to irritate the skin in a good percentage of users.
- Further, there is currently a significant unmet need in managing the excessive sweating and concomitant issues with odor as a result of Hydradenitis suppurativa (irritable infected armpit). This acne-like process in apocine follicles also causes hydradenitis suppurativa, which is often a devastating condition in which very painful cysts and scarring occurs repeatedly in the axillae. The etiology (causes) of this clinical condition is not well understood. However, there are a number of marginally effective approaches to manage this condition. Retinoid drug therapy works marginally but is associated with severe toxicity. Some prescription formulations of antiperspirants can be used, but they are not particularly effective. These preparations can be applied with the addition of an iontophoretic device. This technique however, is not known to be any more effective than the formulation. The sweat glands can be surgically removed from the armpits and/or the sympathetic nerve supply can be interrupted surgically. This approach is fraught with its own drawbacks in terms of morbidity, scarring and cost. BOTOX® is being used ever more for paralyzing the nerve connections that induce excessive sweating in the armpits. However, this is a new approach yet to be completely validated. This technique requires multiple injections (painful) and the results last a few months only (3-4 months), hence need to be repeated. This technique does not get rid of the odor associated with the condition.
- The present invention describes a non-invasive method and system for using therapeutic ultrasound energy for the treatment of conditions resulting from sweat gland disorders. An ultrasound system and method comprises a transducer probe and control system configured to deliver ultrasound energy to the regions of the superficial tissue (e.g., skin) such that the energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
- In accordance with various exemplary embodiments, the ultrasound transducer can be driven at a number of different frequency regimes such that the depth and shape of energy concentration can match the region of treatment. In addition, the ultrasound source or beam radiated from the transducer can be highly focused, weakly focused, or divergent, each in a cylindrical or spherical geometric configuration, and/or can also be planar to radiate a directive beam through the tissue, or various other configurations. Further, the ultrasound field can be varied spatially and temporally in a suitable manner to achieve the optimal tissue effect and/or type of conformal lesion for treating the sweat glands.
- The subject matter of the invention is particularly pointed out in the concluding portion of the specification. The invention, however, both as to organization and method of operation, may best be understood by reference to the following description taken in conjunction with the accompanying drawing figures, in which like parts may be referred to by like numerals:
-
FIG. 1 illustrates a block diagram of an ultrasound therapy system for treating sweat glands in accordance with an exemplary embodiment of the present invention; -
FIG. 2A-2E illustrates schematic diagrams of ultrasound treatment systems configured to treat the sweat glands via direct targeting of heating and damage within the treatment layer in accordance with various exemplary embodiments of the present invention; -
FIGS. 3A and 3B illustrate block diagrams of an exemplary control system in accordance with exemplary embodiments of the present invention; -
FIGS. 4A and 4B illustrate block diagrams of an exemplary probe system in accordance with exemplary embodiments of the present invention; -
FIG. 5 illustrates a cross-sectional diagram of an exemplary transducer in accordance with an exemplary embodiment of the present invention; -
FIGS. 6A and 6B illustrate cross-sectional diagrams of an exemplary transducer in accordance with exemplary embodiments of the present invention; -
FIG. 7 illustrates exemplary transducer configurations for ultrasound treatment in accordance with various exemplary embodiments of the present invention; -
FIGS. 8A and 8B illustrate cross-sectional diagrams of an exemplary transducer in accordance with another exemplary embodiment of the present invention; -
FIG. 9 illustrates an exemplary transducer configured as a two-dimensional array for ultrasound treatment in accordance with an exemplary embodiment of the present invention; -
FIGS. 10A-10F illustrate cross-sectional diagrams of exemplary transducers in accordance with other exemplary embodiments of the present invention; -
FIG. 11 illustrates a schematic diagram of an acoustic coupling and cooling system in accordance with an exemplary embodiment of the present invention; -
FIG. 12 illustrates a block diagram of an ultrasound treatment system combined with additional subsystems and methods of treatment monitoring and/or treatment imaging as well as a secondary treatment subsystem in accordance with an exemplary embodiment of the present invention; and -
FIG. 13 illustrates a schematic diagram with imaging, therapy, or monitoring being provided with one or more active or passive oral inserts in accordance with an exemplary embodiment of the present invention. - The present invention may be described herein in terms of various components and processing steps. It should be appreciated that such components and steps may be realized by any number of hardware components configured to perform the specified functions. For example, the present invention may be configured with various medical treatment devices, visual imaging and display devices, input terminals and the like, which may carry out a variety of functions under the control of one or more control systems or other control devices. In addition, the present invention may be practiced in any number of medical or treatment contexts and that the exemplary embodiments relating to a method and system for sweat gland treatment as described herein are merely a few of the exemplary applications for the invention. For example, the principles, features and methods discussed may be applied to any medical or other tissue or treatment application.
- In accordance with various aspects of the present invention, a non-invasive method and system for the treatment of sweat glands is described. In accordance with an exemplary embodiment, an ultrasound transducer probe and control system are configured to deliver ultrasound energy to a targeted/specified depth and zone where the sweat gland population is required to be treated. The ultrasound beam from the transducer probe can be spatially and/or temporally adjusted, modified or otherwise controlled to match the adequate treatment of the sweat glands in the region of interest.
- For example, in accordance with an exemplary embodiment, with reference to
FIG. 1 , an exemplary treatment system 100 configured to treat a region of interest (ROI) 106 comprises acontrol system 102, an imaging/therapy probe withacoustic coupling 104, and adisplay system 108. -
Control system 102 and display 108 can comprise various configurations for controlling functionality ofprobe 104 and system 100, including for example a microprocessor with software and a plurality of input/output and communication devices, a system for controlling electronic and/or mechanical scanning and/or multiplexing of transducers, a system for power delivery, systems for monitoring, systems for sensing the spatial parameters and/or temporal parameters of the probe and transducers, and/or systems for handling user input and recording treatment input and results, among others. Imaging/therapy probe 104 can comprise various probe and/or transducer configurations. For example, probe 104 can be configured for a combined dual-mode imaging/therapy transducer, coupled or co-housed imaging/therapy transducers, a separate therapy probe and separate imaging probe, or a single therapy probe. In accordance with exemplary embodiments, imaging transducers may operate at frequencies from approximately 2 MHz to 75 MHz or more, while therapy energy can be delivered at frequencies from approximately 500 kHz to 15 MHz, with 2 MHz to 25 MHz being typical. - With reference to
FIG. 2A ,sweat glands 230 are generally located within adermis layer 214 at a depth close tohair bulbs 236. In order to treat sweat glands that require treatment in particular anatomical sites, such as, for example but not limited to, the axillary region (armpit), the palms and soles, an ultrasound transducer probe can be coupled to the skin tissue using one of the numerous coupling media, such as water, mineral oils, gels, and the like. - For example, with reference to
FIG. 2B , in accordance with an exemplary embodiment an exemplary treatment method and system are configured for initially imaging aregion 222 within a region ofinterest 206 and displaying that region 224 on adisplay 208 to facilitate localization of the treatment area and surrounding structures, e.g., identification ofsweat glands 230, such as within the axillary region (armpit), the palms and soles or any other tissue or skin surrounding sweat glands. After localization, delivery ofultrasound energy 220 at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect of thermal ablation to treat asweat gland 230 is provided. Before, during, and/or after therapy, i.e., before, during and/or after delivery of ultrasound energy, monitoring of the treatment area and surrounding structures can be conducted to further planning and assessing of the results and/or providing feedback to controlsystem 202 and a system operator. - In accordance with an exemplary embodiment, localization can be facilitated through ultrasound imaging that can be used to define the position of a
sweat gland 230 and/or the depth ofsweat glands 230 over a region of interest before depositing in a defined pattern at atarget region 220. Such glands can be seen lying alonghair follicles 232 andbulbs 236 and their image may be further enhanced via signal and image processing. Ultrasound imaging can also be used for safety purposes, namely, to avoid injuring vital structures, such asnerve endings 240. In accordance with other exemplary embodiments, localization can also be accomplished withoutimaging region 222, but instead can be based on prior known depths of sweat glands or other target regions, and thus be configured geometrically and/or electronically to selectively deposit energy at a particular known depth belowskin surface 210 to atarget region 220. - The ultrasound beam from
probe 204 can be spatially and/or temporally controlled by changing the spatial parameters of the transducer, such as the placement, distance, treatment depth and transducer structure, as well as by changing the temporal parameters of transducer, such as the frequency, drive amplitude, and timing, with such control handled viacontrol system 202. For example, in some applications, the temporal energy exposure at one location may range from approximately to 40 ms to 40 seconds, while the corresponding source frequency can suitably range from approximately 500 kHz to 15 MHz. Such spatial and temporal parameters can also be suitably monitored and/or utilized in open-loop and/or closed-loop feedback systems within treatment system 200. As a result of such spatial and/or temporal control, conformal lesions of various, specifically targeted, shapes, sizes and orientations can be configured withintarget region 220. - In accordance with an exemplary embodiment, the treatment resulting from ultrasound energy delivery in the region of
sweat glands 230 can be used to achieve selective ablation of regions of sub-epidermal region (0.5-10 mm diameter zones). For example, one or more treatedzones 242 can be configured to produce regions of ablative damage in spatially defined patterns, such as a discrete locus of spaced treatment spots or two- or three- dimensional matrix of damage or destroyed tissue, e.g., a matrix of cross-stitched, ellipsoidal/cigar-shaped, wedge-shaped, mushroom-shaped or any other conformal lesions, rather than heating and destroying the entire volume of the target layer of tissue. In such a treatment where surrounding regions are spared of damage, the surrounding undamaged tissue aids rapid healing and recovery. - In accordance with another exemplary embodiment, a whole contiguous sheet of treatment area can be achieved, whereby all the sweat glands within the said area are ablated. In addition to selective treatment of sweat gland regions, in accordance with another exemplary embodiment, treatment system 200 could be configured to “carpet bomb” the fat layer at 1-7 mm depth, e.g., up to 90% of the sweat glands in the armpit can be ablated without any physiologic issues.
- In accordance with another exemplary embodiment of the present invention, an exemplary monitoring method may comprise monitoring the temperature profile or other tissue parameters of the region of
interest 206, such as attenuation, speed of sound, or mechanical properties such as stiffness and strain of the treatment region and suitably adjust the spatial and/or temporal characteristics and energy levels of the ultrasound therapy transducer ofprobe 204. The results of such monitoring techniques may be indicated ondisplay 208 by means of one-, two-, or three-dimensional images ofmonitoring results 250, or may simply comprise a success or fail-type indicator 252, or combinations thereof. Additional treatment monitoring techniques may be based on one or more of temperature, video, profilometry, and/or stiffness or strain gauges or any other suitable sensing technique. - The non-thermal effects from an acoustic field can also “shock” the sweat producing apocrine and eccrine cells in to reduced activity. These effects mentioned here as examples are, but not limited to, acoustic cavitation, acoustic streaming, inter-cellular shear effects, cell resonant effects, and the like.
- In accordance with an exemplary embodiment, focused or directive ultrasound energy can be used for the treatment of sweat glands in the armpit (without the combination of pharmacological formulations). For example, a clinical indication would be to use in the management of Hidradenitis suppurativa. Ultrasound energy deposited at a selective depth can also be used in combination with a number of pharmaceutical formulations that are currently prescribed for the treatment of sweat gland hyperactivity in the axillary region, palms and soles. The ultrasound energy delivered to the target region in combination with the pharmaceutical agents such as BOTOX® or retinoids can help synergistically treat the sweat gland region by, (1) increasing activity of the agents due to the thermal and non-thermal mechanisms, (2) reduced requirement of overall drug dosage, as well as reducing the drug toxicity, (3) increase local effect of drug in a site selective manner.
- An
exemplary control system 202 anddisplay system 208 may be configured in various manners for controlling probe and system functionality for providing the various exemplary treatment methods illustrated above. For example, with reference toFIGS. 3A and 3B , in accordance with exemplary embodiments, anexemplary control system 300 can be configured for coordination and control of the entire therapeutic treatment process to achieve the desired therapeutic effect of thermal ablation to treat a sweat gland. For example,control system 300 can suitably comprisepower source components 302, sensing andmonitoring components 304, cooling and coupling controls 306, and/or processing andcontrol logic components 308.Control system 300 can be configured and optimized in a variety of ways with more or less subsystems and components to implement the therapeutic system for controlled thermal injury of sweat glands, and the embodiments inFIGS. 3A and 3B are merely for illustration purposes. - For example, for
power sourcing components 302,control system 300 can comprise one or more direct current (DC)power supplies 303 configured to provide electrical energy forentire control system 300, including power required by a transducer electronic amplifier/driver 312. A DCcurrent sense device 305 can also be provided to confirm the level of power going into amplifiers/drivers 312 for safety and monitoring purposes. - Amplifiers/
drivers 312 can comprise multi-channel or single channel power amplifiers and/or drivers. In accordance with an exemplary embodiment for transducer array configurations, amplifiers/drivers 312 can also be configured with a beamformer to facilitate array focusing. An exemplary beamformer can be electrically excited by an oscillator/digitally controlledwaveform synthesizer 310 with related switching logic. - The power sourcing components can also include
various filtering configurations 314. For example, switchable harmonic filters and/or matching may be used at the output of amplifier/driver 312 to increase the drive efficiency and effectiveness.Power detection components 316 may also be included to confirm appropriate operation and calibration. For example, electric power and otherenergy detection components 316 may be used to monitor the amount of power going to an exemplary probe system. - Various sensing and
monitoring components 304 may also be suitably implemented withincontrol system 300. For example, in accordance with an exemplary embodiment, monitoring, sensing andinterface control components 324 may be configured to operate with various motion detection systems implemented withintransducer probe 204 to receive and process information such as acoustic or other spatial and temporal information from a region of interest. Sensing and monitoring components can also include various controls, interfacing andswitches 309 and/orpower detectors 316. Such sensing andmonitoring components 304 can facilitate open-loop and/or closed-loop feedback systems within treatment system 200. - Cooling/
coupling control systems 306 may be provided to remove waste heat from anexemplary probe 204, provide a controlled temperature at the superficial tissue interface and deeper into tissue, and/or provide acoustic coupling fromtransducer probe 204 to region-of-interest 206. Such cooling/coupling control systems 306 can also be configured to operate in both open-loop and/or closed-loop feedback arrangements with various coupling and feedback components. - Processing and
control logic components 308 can comprise various system processors anddigital control logic 307, such as one or more of microcontrollers, microprocessors, field-programmable gate arrays (FPGAs), computer boards, and associated components, including firmware andcontrol software 326, which interfaces to user controls and interfacing circuits as well as input/output circuits and systems for communications, displays, interfacing, storage, documentation, and other useful functions. System software andfirmware 326 controls all initialization, timing, level setting, monitoring, safety monitoring, and all other system functions required to accomplish user-defined treatment objectives. Further,various control switches 308 can also be suitably configured to control operation. - An
exemplary transducer probe 204 can also be configured in various manners and comprise a number of reusable and/or disposable components and parts in various embodiments to facilitate its operation. For example,transducer probe 204 can be configured within any type of transducer probe housing or arrangement for facilitating the coupling of transducer to a tissue interface, with such housing comprising various shapes, contours and configurations.Transducer probe 204 can comprise any type of matching, such as for example, electric matching, which may be electrically switchable; multiplexer circuits and/or aperture/element selection circuits; and/or probe identification devices, to certify probe handle, electric matching, transducer usage history and calibration, such as one or more serial EEPROM (memories).Transducer probe 204 may also comprise cables and connectors; motion mechanisms, motion sensors and encoders; thermal monitoring sensors; and/or user control and status related switches, and indicators such as LEDs. For example, a motion mechanism inprobe 204 may be used to controllably create multiple lesions, or sensing of probe motion itself may be used to controllably create multiple lesions and/or stop creation of lesions, e.g. for safety reasons ifprobe 204 is suddenly jerked or is dropped. In addition, an external motion encoder arm may be used to hold the probe during use, whereby the spatial position and attitude ofprobe 104 is sent to the control system to help controllably create lesions. Furthermore, other sensing functionality such as profilometers or other imaging modalities may be integrated into the probe in accordance with various exemplary embodiments. - With reference to
FIGS. 4A and 4B , in accordance with an exemplary embodiment, atransducer probe 400 can comprise acontrol interface 402, atransducer 404,coupling components 406, and monitoring/sensing components 408, and/ormotion mechanism 410. However,transducer probe 400 can be configured and optimized in a variety of ways with more or less parts and components to provide treatment of sweat glands, and the embodiments inFIGS. 4A and 4B are merely for illustration purposes. -
Control interface 402 is configured for interfacing withcontrol system 300 to facilitate control oftransducer probe 400.Control interface components 402 can comprise multiplexer/aperture select 424, switchable electric matching networks 426, serial EEPROMs and/or other processing components and matching and probeusage information 430 andinterface connectors 432. - Coupling
components 406 can comprise various devices to facilitate coupling oftransducer probe 400 to a region of interest. For example,coupling components 406 can comprise cooling andacoustic coupling system 420 configured for acoustic coupling of ultrasound energy and signals. Acoustic cooling/coupling system 420 with possible connections such as manifolds may be utilized to couple sound into the region-of-interest, control temperature at the interface and deeper into tissue, provide liquid-filled lens focusing, and/or to remove transducer waste heat.Coupling system 420 may facilitate such coupling through use of various coupling mediums, including air and other gases, water and other fluids, gels, solids, and/or any combination thereof, or any other medium that allows for signals to be transmitted between transduceractive elements 412 and a region of interest. In addition to providing a coupling function, in accordance with an exemplary embodiment,coupling system 420 can also be configured for providing temperature control during the treatment application. For example,coupling system 420 can be configured for controlled cooling of an interface surface or region betweentransducer probe 400 and a region of interest and beyond by suitably controlling the temperature of the coupling medium. The suitable temperature for such coupling medium can be achieved in various manners, and utilize various feedback systems, such as thermocouples, thermistors or any other device or system configured for temperature measurement of a coupling medium. Such controlled cooling can be configured to further facilitate spatial and/or thermal energy control oftransducer probe 400. - In accordance with an exemplary embodiment, with additional reference to
FIG. 11 , acoustic coupling and cooling 1140 can be provided to acoustically couple energy and imaging signals fromtransducer probe 1104 to and from the region ofinterest 1106 and deeper into tissue, to provide thermal control at the probe to region-of-interest interface 1110, and to remove potential waste heat from the transducer probe atregion 1144. Temperature monitoring can be provided at the coupling interface via athermal sensor 1146 to provide a mechanism oftemperature measurement 1148 and control viacontrol system 1102 and athermal control system 1142. Thermal control may consist of passive cooling such as via heat sinks or natural conduction and convection or via active cooling such as with peltier thermoelectric coolers, refrigerants, or fluid-based systems comprised of pump, fluid reservoir, bubble detection, flow sensor, flow channels/tubing 1144 andthermal control 1142. - With continued reference to
FIG. 4 , monitoring andsensing components 408 can comprise various motion and/orposition sensors 416,temperature monitoring sensors 418, user control and feedback switches 414 and other like components for facilitating control bycontrol system 300, e.g., to facilitate spatial and/or temporal control through open-loop and closed-loop feedback arrangements that monitor various spatial and temporal characteristics. -
Motion mechanism 410 can comprise manual operation, mechanical arrangements, or some combination thereof. For example, amotion mechanism 422 can be suitably controlled bycontrol system 300, such as through the use of accelerometers, encoders or other position/orientation devices 416 to determine and enable movement and positions oftransducer probe 400. Linear, rotational or variable movement can be facilitated, e.g., those depending on the treatment application and tissue contour surface. -
Transducer 404 can comprise one or more transducers configured for treating of sweat glands and targeted regions.Transducer 404 can also comprise one or more transduction elements and/orlenses 412. The transduction elements can comprise a piezoelectrically active material, such as lead zirconante titanate (PZT), or any other piezoelectrically active material, such as a piezoelectric ceramic, crystal, plastic, and/or composite materials, as well as lithium niobate, lead titanate, barium titanate, and/or lead metaniobate. In addition to, or instead of, a piezoelectrically active material,transducer 404 can comprise any other materials configured for generating radiation and/or acoustical energy.Transducer 404 can also comprise one or more matching layers configured along with the transduction element such as coupled to the piezoelectrically active material. Acoustic matching layers and/or damping may be employed as necessary to achieve the desired electroacoustic response. - In accordance with an exemplary embodiment, the thickness of the transduction element of
transducer 404 can be configured to be uniform. That is, atransduction element 412 can be configured to have a thickness that is substantially the same throughout. In accordance with another exemplary embodiment, the thickness of atransduction element 412 can also be configured to be variable. For example, transduction element(s) 412 oftransducer 404 can be configured to have a first thickness selected to provide a center operating frequency of approximately 2 kHz to 75 MHz, such as for imaging applications.Transduction element 412 can also be configured with a second thickness selected to provide a center operating frequency of approximately 2 to 50 MHz, and typically between 2 MHz and 25 MHz for therapy application.Transducer 404 can be configured as a single broadband transducer excited with at least two or more frequencies to provide an adequate output for generating a desired response.Transducer 404 can also be configured as two or more individual transducers, wherein each transducer comprises one or more transduction element. The thickness of the transduction elements can be configured to provide center-operating frequencies in a desired treatment range. -
Transducer 404 may be composed of one or more individual transducers in any combination of focused, planar, or unfocused single-element, multi-element, or array transducers, including 1-D, 2-D, and annular arrays; linear, curvilinear, sector, or spherical arrays; spherically, cylindrically, and/or electronically focused, defocused, and/or lensed sources. For example, with reference to an exemplary embodiment depicted inFIG. 5 ,transducer 500 can be configured as an acoustic array to facilitate phase focusing. That is,transducer 500 can be configured as an array of electronic apertures that may be operated by a variety of phases via variable electronic time delays. By the term “operated,” the electronic apertures oftransducer 500 may be manipulated, driven, used, and/or configured to produce and/or deliver an energy beam corresponding to the phase variation caused by the electronic time delay. For example, these phase variations can be used to deliver defocused beams, planar beams, and/or focused beams, each of which may be used in combination to achieve different physiological effects in a region ofinterest 510.Transducer 500 may additionally comprise any software and/or other hardware for generating, producing and or driving a phased aperture array with one or more electronic time delays. -
Transducer 500 can also be configured to provide focused treatment to one or more regions of interest using various frequencies. In order to provide focused treatment,transducer 500 can be configured with one or more variable depth devices to facilitate treatment. For example,transducer 500 may be configured with variable depth devices disclosed in U.S. patent application Ser. No. 10/944,500, entitled “System and Method for Variable Depth Ultrasound”, filed on Sep. 16, 2004, having at least one common inventor and a common Assignee as the present application, and incorporated herein by reference. In addition,transducer 500 can also be configured to treat one or moreadditional ROI 510 through the enabling of sub-harmonics or pulse-echo imaging, as disclosed in U.S. patent application Ser. No. 10/944,499, entitled “Method and System for Ultrasound Treatment with a Multi-directional Transducer”, filed on Sep. 16, 2004, having at least one common inventor and a common Assignee as the present application, and also incorporated herein by reference. - Moreover, any variety of mechanical lenses or variable focus lenses, e.g. liquid-filled lenses, may also be used to focus and or defocus the sound field. For example, with reference to exemplary embodiments depicted in
FIGS. 6A and 6B ,transducer 600 may also be configured with an electronic focusingarray 604 in combination with one ormore transduction elements 606 to facilitate increased flexibility in treatingROI 610.Array 604 may be configured in a manner similar to transducer 502. That is,array 604 can be configured as an array of electronic apertures that may be operated by a variety of phases via variable electronic time delays, for example, T1, T2 . . . Tj. By the term “operated,” the electronic apertures ofarray 604 may be manipulated, driven, used, and/or configured to produce and/or deliver energy in a manner corresponding to the phase variation caused by the electronic time delay. For example, these phase variations can be used to deliver defocused beams, planar beams, and/or focused beams, each of which may be used in combination to achieve different physiological effects inROI 610. -
Transduction elements 606 may be configured to be concave, convex, and/or planar. For example, in an exemplary embodiment depicted inFIG. 6A , transduction elements 606A are configured to be concave in order to provide focused energy for treatment ofROI 610. Additional embodiments are disclosed in U.S. patent application Ser. No. 10/944,500, entitled “Variable Depth Transducer System and Method”, and again incorporated herein by reference. - In another exemplary embodiment, depicted in
FIG. 6B , transduction elements 606B can be configured to be substantially flat in order to provide substantially uniform energy toROI 610. WhileFIGS. 6A and 6B depict exemplary embodiments withtransduction elements 604 configured as concave and substantially flat, respectively,transduction elements 604 can be configured to be concave, convex, and/or substantially flat. In addition,transduction elements 604 can be configured to be any combination of concave, convex, and/or substantially flat structures. For example, a first transduction element can be configured to be concave, while a second transduction element can be configured to be substantially flat. - With reference to
FIGS. 8A and 8B ,transducer 404 can be configured as single-element arrays, wherein a single-element 802, e.g., a transduction element of various structures and materials, can be configured with a plurality ofmasks 804, such masks comprising ceramic, metal or any other material or structure for masking or altering energy distribution fromelement 802, creating an array of energy distributions 808.Masks 804 can be coupled directly toelement 802 or separated by astandoff 806, such as any suitably solid or liquid material. - An
exemplary transducer 404 can also be configured as an annular array to provide planar, focused and/or defocused acoustical energy. For example, with reference toFIGS. 10A and 10B , in accordance with an exemplary embodiment, anannular array 1000 can comprise a plurality ofrings N. Rings annular array 1000 can also be provided to aid focusing or defocusing such that any time differential delays can be reduced. Movement of annular array 800 in one, two or three-dimensions, or along any path, such as through use of probes and/or any conventional robotic arm mechanisms, may be implemented to scan and/or treat a volume or any corresponding space within a region of interest. -
Transducer 404 can also be configured in other annular or non-array configurations for imaging/therapy functions. For example, with reference toFIGS. 10C-10F , a transducer can comprise animaging element 1012 configured with therapy element(s) 1014.Elements standoff 1024 or other matching layers, or any combination thereof. For example, with particular reference toFIG. 10F , a transducer can comprise animaging element 1012 having asurface 1028 configured for focusing, defocusing or planar energy distribution, withtherapy elements 1014 including a stepped-configuration lens configured for focusing, defocusing, or planar energy distribution. - In accordance with various exemplary embodiments of the present invention,
transducer 404 may be configured to provide one, two and/or three-dimensional treatment applications for focusing acoustic energy to one or more regions of interest. For example, as discussed above,transducer 404 can be suitably diced to form a one-dimensional array, e.g.,transducer 602 comprising a single array of sub-transduction elements. - In accordance with another exemplary embodiment,
transducer 404 may be suitably diced in two-dimensions to form a two-dimensional array. For example, with reference toFIG. 9 , an exemplary two-dimensional array 900 can be suitably diced into a plurality of two-dimensional portions 902. Two-dimensional portions 902 can be suitably configured to focus on the treatment region at a certain depth, and thus providerespective slices 904 of the treatment region. As a result, the two-dimensional array 900 can provide a two-dimensional slicing of the image place of a treatment region, thus providing two-dimensional treatment. - In accordance with another exemplary embodiment,
transducer 404 may be suitably configured to provide three-dimensional treatment. For example, to provide-three dimensional treatment of a region of interest, with reference again toFIG. 1 , a three-dimensional system can comprise a transducer withinprobe 104 configured with an adaptive algorithm, such as, for example, one utilizing three-dimensional graphic software, contained in a control system, such ascontrol system 102. The adaptive algorithm is suitably configured to receive two-dimensional imaging, temperature and/or treatment or other tissue parameter information relating to the region of interest, process the received information, and then provide corresponding three-dimensional imaging, temperature and/or treatment information. - In accordance with an exemplary embodiment, with reference again to
FIG. 9 , an exemplary three-dimensional system can comprise a two-dimensional array 900 configured with an adaptive algorithm to suitably receive 904 slices from different image planes of the treatment region, process the received information, and then providevolumetric information 906, e.g., three-dimensional imaging, temperature and/or treatment information. Moreover, after processing the received information with the adaptive algorithm, the two-dimensional array 900 may suitably provide therapeutic heating to thevolumetric region 906 as desired. - In accordance with other exemplary embodiments, rather than utilizing an adaptive algorithm, such as three-dimensional software, to provide three-dimensional imaging and/or temperature information, an exemplary three-dimensional system can comprise a
single transducer 404 configured within a probe arrangement to operate from various rotational and/or translational positions relative to a target region. - To further illustrate the various structures for
transducer 404, with reference toFIG. 7 ,ultrasound therapy transducer 700 can be configured for a single focus, an array of foci, a locus of foci, a line focus, and/or diffraction patterns.Transducer 700 can also comprise single elements, multiple elements, annular arrays, one-, two-, or three-dimensional arrays, broadband transducers, and/or combinations thereof, with or without lenses, acoustic components, and mechanical and/or electronic focusing. Transducers configured as spherically focusedsingle elements 702,annular arrays 704, annular arrays with damped regions 706, line focusedsingle elements 708, 1-Dlinear arrays 710, 1-D curvilinear arrays in concave or convex form, with or without elevation focusing, 2-D arrays, and 3-D spatial arrangements of transducers may be used to perform therapy and/or imaging and acoustic monitoring functions. For any transducer configuration, focusing and/or defocusing may be in one plane or two planes viamechanical focus 720,convex lens 722,concave lens 724, compound or multiple lenses 726,planar form 728, or stepped form, such as illustrated inFIG. 10F . Any transducer or combination of transducers may be utilized for treatment. For example, an annular transducer may be used with an outer portion dedicated to therapy and the inner disk dedicated to broadband imaging wherein such imaging transducer and therapy transducer have different acoustic lenses and design, such as illustrated inFIG. 10C-10F . - Moreover,
such transduction elements 700 may comprise a piezoelectrically active material, such as lead zirconante titanate (PZT), or any other piezoelectrically active material, such as a piezoelectric ceramic, crystal, plastic, and/or composite materials, as well as lithium niobate, lead titanate, barium titanate, and/or lead metaniobate.Transduction elements 700 may also comprise one or more matching layers configured along with the piezoelectrically active material. In addition to or instead of piezoelectrically active material,transduction elements 700 can comprise any other materials configured for generating radiation and/or acoustical energy. A means of transferring energy to and from the transducer to the region of interest is provided. - In accordance with another exemplary embodiment, with reference to
FIG. 12 , an exemplary treatment system 200 can be configured with and/or combined with various auxiliary systems to provide additional functions. For example, anexemplary treatment system 1200 for treatment of sweat glands can further comprise anauxiliary imaging modality 1272 and/orauxiliary monitoring modality 1274 may be based upon at least one of photography and other visual optical methods, magnetic resonance imaging (MRI), computed tomography (CT), optical coherence tomography (OCT), electromagnetic, microwave, or radio frequency (RF) methods, positron emission tomography (PET), infrared, ultrasound, acoustic, or any other suitable method of visualization, localization, or monitoring of the region-of-interest, including imaging/monitoring enhancements. Such imaging/monitoring enhancement for ultrasound imaging viaprobe 1204 andcontrol system 1202 can comprise M-mode, persistence, filtering, color, Doppler, and harmonic imaging among others; furthermore anultrasound treatment system 1270, as a primary source of treatment, may be combined with a secondary source oftreatment 1276, including radio frequency (RF), intense pulsed light (IPL), laser, infrared laser, microwave, or any other suitable energy source. - In accordance with another exemplary embodiment, with reference to
FIG. 13 , treatment composed of imaging, monitoring, and/or therapy to a region ofinterest 1302 and/or 1308 may be aided, augmented, and/or delivered with passive oractive devices 1304 and/or 1306 within the oral and/or nasal cavity, respectively. For example, if passive oractive device 1304 and/or 1306 are second transducers or acoustic reflectors acoustically coupled to the mucous membranes it is possible to obtain through transmission, tomographic, or round-trip acoustic waves which are useful for treatment monitoring, such as in measuring acoustic speed of sound and attenuation, which are temperature dependent; furthermore such transducers could be used to treat and/or image. In addition an active, passive, or active/passive object 1304 and/or 1306 may be used to flatten the skin, and/or may be used as an imaging grid, marker, or beacon, to aid determination of position. A passive oractive device 1304 and/or 1306 may also be used to aid cooling or temperature control. Natural air in the oral cavity and/or nasal cavity may also be used aspassive device 1304 and/or 1306 whereby it may be utilized to as an acoustic reflector to aid thickness measurement and monitoring function. - The present invention may be described herein in terms of various functional components and processing steps. It should be appreciated that such components and steps may be realized by any number of hardware components configured to perform the specified functions. For example, the present invention may employ various medical treatment devices, visual imaging and display devices, input terminals and the like, which may carry out a variety of functions under the control of one or more control systems or other control devices. In addition, the present invention may be practiced in any number of medical contexts and that the exemplary embodiments relating to a system as described herein are merely indicative of exemplary applications for the invention. For example, the principles, features and methods discussed may be applied to any medical application. Further, various aspects of the present invention may be suitably applied to other applications, such as other medical or industrial applications.
Claims (22)
1. An ultrasound treatment system configured for treatment of sweat glands, said ultrasound treatment system comprising:
a control system for facilitating control of the ultrasound treatment system; and
a probe system configured for targeted delivery of ultrasound energy to produce a treatment region for destroying said sweat gland.
2. The ultrasound treatment system according to claim 1 , wherein said probe system is configured for destroying the sweat gland within a specified treatment depth identified through localization of said sweat gland.
3. The ultrasound treatment system according to claim 1 , wherein said spatially defined patterns comprise a discrete locus of spaced lesions comprising at least one of cross-stitch, cigar-shaped, ellipsoidal, mushroom-shaped and wedge-shaped lesions.
4. The ultrasound treatment system of claim 1 , wherein said control system comprises an imaging system configured for monitoring of said treatment region prior to, during and after delivery of ultrasound energy into said sweat gland.
5. The ultrasound treatment system of claim 4 , wherein said imaging system is configured to provide feedback to facilitate said targeted delivery.
6. The ultrasound treatment system according to claim 1 , wherein said display system comprises a display of images corresponding to a temperature profile of said treatment region.
7. The ultrasound treatment system according to claim 1 , wherein said probe system comprises an imaging and therapy transducer configured for targeted delivery of ablative ultrasound within said sweat gland.
8. The ultrasound treatment system according to claim 7 , wherein said imaging and therapy transducer comprise a combined transducer within an electronic array of transduction elements.
9. The ultrasound treatment system according to claim 7 , wherein said imaging and therapy transducer comprises a single element array comprising a single transduction element and a plurality of masks configured for generating a plurality of ablative zones with each of said plurality of ablative zones providing at least one of focused, defocused and planar ultrasound energy distribution.
10. The ultrasound treatment system according to claim 1 , wherein said probe is configured for targeted delivery of ultrasound energy through adjustable control of spatial parameters and temporal parameters of said probe to generate conformal lesions of specifically targeted shapes, sizes and orientations.
11. The ultrasound treatment system according to claim 1 , wherein said treatment system comprises an imaging, therapy, and treatment monitoring system combined with auxiliary imaging and treatment monitoring apparatus and secondary therapy systems, and wherein said auxiliary imaging apparatus comprises at least one of a photographic instrument and an optical modality.
12. The ultrasound treatment system according to claim 1 , wherein said control system comprises an imaging system configured for facilitating at least one of one-dimensional, two-dimensional and three-dimensional imaging or therapy.
13. A method for providing treatment of acne and sweat glands, said method comprising:
localizing of at least one targeted region within a region of interest, said localizing configured for identifying at least one sweat gland;
targeting of delivery of ablative ultrasound energy from a transducer probe to said at least one sweat gland; and
monitoring of results of said targeted delivery within said at least one sweat gland during and after said targeted delivery to continue planning of treatment.
14. The method of claim 13 , wherein said localizing comprises imaging a region of interest to identify said at least one sweat gland.
15. The method of claim 13 , said targeting of delivery of ultrasound energy comprises destroying said sweat gland within a specified treatment depth identified through localization of said sweat gland.
16. The method of claim 13 , wherein said targeting of delivery comprises adjustable control of spatial parameters and temporal parameters of said transducer probe to generate conformal lesions of specifically targeted shapes, sizes and orientations.
17. The method of claim 13 , wherein said monitoring of results comprises measurement of results of treatment of said at least one sweat gland as visualized during and after said target delivery of ablative ultrasound.
18. The method of claim 13 , wherein said monitoring comprises monitoring the temperature profile of said targeted region.
19. The method of claim 13 , wherein said targeted delivery comprises producing of a matrix of spaced treatment spots comprising at least one of two-dimensional and three-dimensional matrix of lesions along a scanned pattern created by scanning of said transducer probe.
20. The method according to claim 19 , wherein producing said spatially defined patterns comprises producing a discrete locus of spaced conformal lesions based on control of spatial and temporal parameters.
21. The method according to claim 13 , wherein said localizing comprises generating three-dimensional imaging information and said targeting comprises treating three-dimensional treatment region.
22. The method according to claim 13 , wherein said targeting of delivery further comprises cooling through any tissue regions between and including skin and said at least one sweat gland to facilitate treatment.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/163,152 US20060111744A1 (en) | 2004-10-13 | 2005-10-06 | Method and system for treatment of sweat glands |
US13/444,485 US8282554B2 (en) | 2004-10-06 | 2012-04-11 | Methods for treatment of sweat glands |
US13/603,279 US8523775B2 (en) | 2004-10-06 | 2012-09-04 | Energy based hyperhidrosis treatment |
US13/603,159 US8333700B1 (en) | 2004-10-06 | 2012-09-04 | Methods for treatment of hyperhidrosis |
US13/950,728 US8932224B2 (en) | 2004-10-06 | 2013-07-25 | Energy based hyperhidrosis treatment |
US14/571,835 US9421029B2 (en) | 2004-10-06 | 2014-12-16 | Energy based hyperhidrosis treatment |
US15/243,081 US10046181B2 (en) | 2004-10-06 | 2016-08-22 | Energy based hyperhidrosis treatment |
US16/049,364 US10960235B2 (en) | 2004-10-06 | 2018-07-30 | Energy based hyperhidrosis treatment |
US17/209,808 US11235179B2 (en) | 2004-10-06 | 2021-03-23 | Energy based skin gland treatment |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61775204P | 2004-10-13 | 2004-10-13 | |
US11/163,152 US20060111744A1 (en) | 2004-10-13 | 2005-10-06 | Method and system for treatment of sweat glands |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/444,485 Continuation US8282554B2 (en) | 2004-10-06 | 2012-04-11 | Methods for treatment of sweat glands |
Publications (1)
Publication Number | Publication Date |
---|---|
US20060111744A1 true US20060111744A1 (en) | 2006-05-25 |
Family
ID=46577903
Family Applications (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/163,152 Abandoned US20060111744A1 (en) | 2004-10-06 | 2005-10-06 | Method and system for treatment of sweat glands |
US13/444,485 Active US8282554B2 (en) | 2004-10-06 | 2012-04-11 | Methods for treatment of sweat glands |
US13/603,279 Active US8523775B2 (en) | 2004-10-06 | 2012-09-04 | Energy based hyperhidrosis treatment |
US13/603,159 Active US8333700B1 (en) | 2004-10-06 | 2012-09-04 | Methods for treatment of hyperhidrosis |
US13/950,728 Active US8932224B2 (en) | 2004-10-06 | 2013-07-25 | Energy based hyperhidrosis treatment |
US14/571,835 Active 2025-11-23 US9421029B2 (en) | 2004-10-06 | 2014-12-16 | Energy based hyperhidrosis treatment |
US15/243,081 Active 2026-02-13 US10046181B2 (en) | 2004-10-06 | 2016-08-22 | Energy based hyperhidrosis treatment |
US16/049,364 Active 2026-09-03 US10960235B2 (en) | 2004-10-06 | 2018-07-30 | Energy based hyperhidrosis treatment |
Family Applications After (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/444,485 Active US8282554B2 (en) | 2004-10-06 | 2012-04-11 | Methods for treatment of sweat glands |
US13/603,279 Active US8523775B2 (en) | 2004-10-06 | 2012-09-04 | Energy based hyperhidrosis treatment |
US13/603,159 Active US8333700B1 (en) | 2004-10-06 | 2012-09-04 | Methods for treatment of hyperhidrosis |
US13/950,728 Active US8932224B2 (en) | 2004-10-06 | 2013-07-25 | Energy based hyperhidrosis treatment |
US14/571,835 Active 2025-11-23 US9421029B2 (en) | 2004-10-06 | 2014-12-16 | Energy based hyperhidrosis treatment |
US15/243,081 Active 2026-02-13 US10046181B2 (en) | 2004-10-06 | 2016-08-22 | Energy based hyperhidrosis treatment |
US16/049,364 Active 2026-09-03 US10960235B2 (en) | 2004-10-06 | 2018-07-30 | Energy based hyperhidrosis treatment |
Country Status (1)
Country | Link |
---|---|
US (8) | US20060111744A1 (en) |
Cited By (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060089632A1 (en) * | 2004-10-06 | 2006-04-27 | Guided Therapy Systems, L.L.C. | Method and system for treating acne and sebaceous glands |
US20070213705A1 (en) * | 2006-03-08 | 2007-09-13 | Schmid Peter M | Insulated needle and system |
US20080021353A1 (en) * | 2005-12-30 | 2008-01-24 | Manfred Menzi | Acoustic pressure wave applicator system with conduction pad |
US20080139974A1 (en) * | 2006-12-04 | 2008-06-12 | Da Silva Luiz B | Devices and Methods for Treatment of Skin Conditions |
US20090062724A1 (en) * | 2007-08-31 | 2009-03-05 | Rixen Chen | System and apparatus for sonodynamic therapy |
US20090093737A1 (en) * | 2007-10-09 | 2009-04-09 | Cabochon Aesthetics, Inc. | Ultrasound apparatus with treatment lens |
WO2008131302A3 (en) * | 2007-04-19 | 2009-12-30 | The Foundry, Inc. | Methods and apparatus for reducing sweat production |
ITTR20080006A1 (en) * | 2008-12-17 | 2010-06-18 | Med Elettronica Srl | TRANSDUCER FOR LOCALIZED TREATMENTS BY MECHANICAL ULTRASOUND STRENGTH WITH COOLING SYSTEM WITH INTEGRATED SINK |
US7758524B2 (en) | 2004-10-06 | 2010-07-20 | Guided Therapy Systems, L.L.C. | Method and system for ultra-high frequency ultrasound treatment |
US20100222852A1 (en) * | 2009-02-24 | 2010-09-02 | Vasily David B | Apparatus and Method for Decolonizing Microbes on the Surfaces of the Skin and In Body Cavities |
US7824348B2 (en) | 2004-09-16 | 2010-11-02 | Guided Therapy Systems, L.L.C. | System and method for variable depth ultrasound treatment |
US20110196365A1 (en) * | 2008-10-22 | 2011-08-11 | Miramar Labs, Inc. | Systems, Apparatus, Methods, and Procedures for the Non-Invasive Treatment of Tissue Using Microwave Energy |
US20110201976A1 (en) * | 2005-06-01 | 2011-08-18 | Focus Surgery, Inc. | Laparoscopic hifu probe |
US8073550B1 (en) | 1997-07-31 | 2011-12-06 | Miramar Labs, Inc. | Method and apparatus for treating subcutaneous histological features |
US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
US8166332B2 (en) | 2005-04-25 | 2012-04-24 | Ardent Sound, Inc. | Treatment system for enhancing safety of computer peripheral for use with medical devices by isolating host AC power |
US20120165668A1 (en) * | 2010-08-02 | 2012-06-28 | Guided Therapy Systems, Llc | Systems and methods for treating acute and/or chronic injuries in soft tissue |
US8235909B2 (en) | 2004-05-12 | 2012-08-07 | Guided Therapy Systems, L.L.C. | Method and system for controlled scanning, imaging and/or therapy |
US8282554B2 (en) | 2004-10-06 | 2012-10-09 | Guided Therapy Systems, Llc | Methods for treatment of sweat glands |
WO2013009785A2 (en) | 2011-07-10 | 2013-01-17 | Guided Therapy Systems, Llc. | Systems and methods for improving an outside appearance of skin using ultrasound as an energy source |
WO2013012641A1 (en) | 2011-07-11 | 2013-01-24 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US8401668B2 (en) | 2007-04-19 | 2013-03-19 | Miramar Labs, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
US8406894B2 (en) | 2007-12-12 | 2013-03-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US8409097B2 (en) | 2000-12-28 | 2013-04-02 | Ardent Sound, Inc | Visual imaging system for ultrasonic probe |
US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
US20130123625A1 (en) * | 2011-11-14 | 2013-05-16 | Boston Scientific Scimed, Inc. | Integrated ultrasound ablation and imaging device and related methods |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US8469951B2 (en) | 2011-08-01 | 2013-06-25 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US8480585B2 (en) | 1997-10-14 | 2013-07-09 | Guided Therapy Systems, Llc | Imaging, therapy and temperature monitoring ultrasonic system and method |
JP2013176628A (en) * | 2007-04-19 | 2013-09-09 | Miramar Labs Inc | Method and apparatus for reducing sweat production |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US8574251B2 (en) | 2005-09-07 | 2013-11-05 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
DE102012209008A1 (en) * | 2012-05-29 | 2013-12-05 | Wellcomet Gmbh | Device for generation of e.g. radio frequency current for pressurization of human tissue with frequency current, has motion sensor cooperating with control unit such that intensity of wave is controlled depending on measurement signals |
US8663112B2 (en) | 2004-10-06 | 2014-03-04 | Guided Therapy Systems, Llc | Methods and systems for fat reduction and/or cellulite treatment |
US8688228B2 (en) | 2007-04-19 | 2014-04-01 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US8764687B2 (en) | 2007-05-07 | 2014-07-01 | Guided Therapy Systems, Llc | Methods and systems for coupling and focusing acoustic energy using a coupler member |
US8852103B2 (en) | 2011-10-17 | 2014-10-07 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
US8915870B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Method and system for treating stretch marks |
US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
US9114247B2 (en) | 2004-09-16 | 2015-08-25 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment with a multi-directional transducer |
US9216276B2 (en) | 2007-05-07 | 2015-12-22 | Guided Therapy Systems, Llc | Methods and systems for modulating medicants using acoustic energy |
US9241763B2 (en) | 2007-04-19 | 2016-01-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US9241683B2 (en) | 2006-10-04 | 2016-01-26 | Ardent Sound Inc. | Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
US9272124B2 (en) | 2005-12-02 | 2016-03-01 | Ulthera, Inc. | Systems and devices for selective cell lysis and methods of using same |
US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US9566454B2 (en) | 2006-09-18 | 2017-02-14 | Guided Therapy Systems, Llc | Method and sysem for non-ablative acne treatment and prevention |
US20170080198A1 (en) * | 2015-09-22 | 2017-03-23 | Johnson & Johnson Consummer Inc. | Devices and methods for enhancing the topical application of a benefit agent |
US9667889B2 (en) | 2013-04-03 | 2017-05-30 | Butterfly Network, Inc. | Portable electronic devices with integrated imaging capabilities |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US20170340384A1 (en) * | 2007-04-19 | 2017-11-30 | Mark E. Deem | Systems and methods for creating an effect using microwave energy to specified tissue |
US20190009110A1 (en) * | 2017-07-06 | 2019-01-10 | Slender Medical Ltd. | Ultrasound energy applicator |
US10420960B2 (en) | 2013-03-08 | 2019-09-24 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
US10463429B2 (en) | 2007-04-19 | 2019-11-05 | Miradry, Inc. | Methods, devices, and systems for non-invasive delivery of microwave therapy |
US10537304B2 (en) | 2008-06-06 | 2020-01-21 | Ulthera, Inc. | Hand wand for ultrasonic cosmetic treatment and imaging |
US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
US10561862B2 (en) | 2013-03-15 | 2020-02-18 | Guided Therapy Systems, Llc | Ultrasound treatment device and methods of use |
US10603521B2 (en) | 2014-04-18 | 2020-03-31 | Ulthera, Inc. | Band transducer ultrasound therapy |
US10779885B2 (en) | 2013-07-24 | 2020-09-22 | Miradry. Inc. | Apparatus and methods for the treatment of tissue using microwave energy |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US11224895B2 (en) | 2016-01-18 | 2022-01-18 | Ulthera, Inc. | Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board and method of assembly thereof |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US11241218B2 (en) | 2016-08-16 | 2022-02-08 | Ulthera, Inc. | Systems and methods for cosmetic ultrasound treatment of skin |
US11717661B2 (en) | 2007-05-07 | 2023-08-08 | Guided Therapy Systems, Llc | Methods and systems for ultrasound assisted delivery of a medicant to tissue |
US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US11944849B2 (en) | 2018-02-20 | 2024-04-02 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
US11969609B2 (en) | 2022-12-05 | 2024-04-30 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8840608B2 (en) | 2002-03-15 | 2014-09-23 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
EP1490005B1 (en) * | 2002-03-15 | 2008-02-20 | The General Hospital Corporation | Devices for selective disruption of fatty tissue by controlled cooling |
BRPI0418242A (en) * | 2003-12-30 | 2007-04-17 | Liposonix Inc | transducer for ultrasound, transducer assemblies and interchangeable electronic medical instruments |
EP1699407A4 (en) * | 2003-12-30 | 2010-12-01 | Medicis Technologies Corp | Ultrasound therapy head with movement control |
US7530356B2 (en) * | 2004-10-06 | 2009-05-12 | Guided Therapy Systems, Inc. | Method and system for noninvasive mastopexy |
US10219815B2 (en) | 2005-09-22 | 2019-03-05 | The Regents Of The University Of Michigan | Histotripsy for thrombolysis |
US8920320B2 (en) * | 2006-03-10 | 2014-12-30 | Liposonix, Inc. | Methods and apparatus for coupling a HIFU transducer to a skin surface |
US8192474B2 (en) | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US9132031B2 (en) | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US20080287839A1 (en) | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
US8285390B2 (en) | 2007-08-21 | 2012-10-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
CN101959556B (en) * | 2008-02-01 | 2013-11-27 | 麦迪斯技术公司 | Therapy head for use with ultrasound system |
US20090248578A1 (en) * | 2008-03-20 | 2009-10-01 | Liposonix, Inc. | Methods and apparatus for medical device investment recovery |
US8603073B2 (en) | 2008-12-17 | 2013-12-10 | Zeltiq Aesthetics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
AR076081A1 (en) * | 2009-03-04 | 2011-05-18 | Medicis Technologies Corp | PROVISION FOR THE TREATMENT BY ULTRASOUND OF TISSUE ADIPOSE TO MULTIPLE DEPTHS |
PL2411095T3 (en) * | 2009-03-23 | 2016-02-29 | Liposonix Inc | Method of determining functionality of an ultrasound therapy head |
CA3075147C (en) | 2009-04-30 | 2022-06-21 | Zeltiq Aesthetics, Inc. | Device, system and method of removing heat from subcutaneous lipid-rich cells |
US8932238B2 (en) * | 2009-09-29 | 2015-01-13 | Liposonix, Inc. | Medical ultrasound device with liquid dispensing device coupled to a therapy head |
EP2528560A1 (en) | 2010-01-25 | 2012-12-05 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods |
US20110196438A1 (en) * | 2010-02-10 | 2011-08-11 | Lukas Mnozil | Therapy device and method for treating underlying tissue using electrical and acoustic energies |
US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
US8573392B2 (en) | 2010-09-22 | 2013-11-05 | Liposonix, Inc. | Modified atmosphere packaging for ultrasound transducer cartridge |
US10722395B2 (en) | 2011-01-25 | 2020-07-28 | Zeltiq Aesthetics, Inc. | Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells |
US9675819B2 (en) * | 2012-07-16 | 2017-06-13 | Mirabilis Medica, Inc. | Human interface and device for ultrasound guided treatment |
EP2903688A4 (en) | 2012-10-05 | 2016-06-15 | Univ Michigan | Bubble-induced color doppler feedback during histotripsy |
US20140207213A1 (en) * | 2013-01-23 | 2014-07-24 | Khalilullah A. Khatri | Laser method for treating hyperhidrosis targeting sweat glands |
US20140221877A1 (en) * | 2013-02-01 | 2014-08-07 | Moshe Ein-Gal | Pressure-assisted irreversible electroporation |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
US20140276053A1 (en) * | 2013-03-14 | 2014-09-18 | SonaCare Medical, LLC | Multi-element therapy and imaging transducer for ultrasound therapy |
US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
WO2015003154A1 (en) | 2013-07-03 | 2015-01-08 | Histosonics, Inc. | Articulating arm limiter for cavitational ultrasound therapy system |
US10780298B2 (en) | 2013-08-22 | 2020-09-22 | The Regents Of The University Of Michigan | Histotripsy using very short monopolar ultrasound pulses |
WO2015117001A1 (en) | 2014-01-31 | 2015-08-06 | Zeltiq Aesthetics, Inc. | Compositions, treatment systems and methods for improved cooling of lipid-rich tissue |
US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US10004610B2 (en) | 2015-02-04 | 2018-06-26 | DePuy Synthes Products, Inc. | Non-invasive methods for modifying tissue to facilitate treatment |
WO2016210133A1 (en) | 2015-06-24 | 2016-12-29 | The Regents Of The Universtiy Of Michigan | Histotripsy therapy systems and methods for the treatment of brain tissue |
WO2017070112A1 (en) | 2015-10-19 | 2017-04-27 | Zeltiq Aesthetics, Inc. | Vascular treatment systems, cooling devices, and methods for cooling vascular structures |
CA3009414A1 (en) | 2016-01-07 | 2017-07-13 | Zeltiq Aesthetics, Inc. | Temperature-dependent adhesion between applicator and skin during cooling of tissue |
US11213350B2 (en) | 2016-02-12 | 2022-01-04 | Sciton, Inc. | Devices for image-guided light treatment of skin |
US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
US11076879B2 (en) | 2017-04-26 | 2021-08-03 | Zeltiq Aesthetics, Inc. | Shallow surface cryotherapy applicators and related technology |
WO2020028472A1 (en) | 2018-07-31 | 2020-02-06 | Zeltiq Aesthetics, Inc. | Methods, devices, and systems for improving skin characteristics |
AU2019389001A1 (en) | 2018-11-28 | 2021-06-10 | Histosonics, Inc. | Histotripsy systems and methods |
US11813485B2 (en) | 2020-01-28 | 2023-11-14 | The Regents Of The University Of Michigan | Systems and methods for histotripsy immunosensitization |
Citations (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3913386A (en) * | 1973-01-16 | 1975-10-21 | Commissariat Energie Atomique | Method of compensation for the angle of refraction of an ultrasonic beam and a device for the application of said method |
US3965455A (en) * | 1974-04-25 | 1976-06-22 | The United States Of America As Represented By The Secretary Of The Navy | Focused arc beam transducer-reflector |
US3992925A (en) * | 1973-12-10 | 1976-11-23 | U.S. Philips Corporation | Device for ultrasonic scanning |
US4039312A (en) * | 1972-07-04 | 1977-08-02 | Marcel Joseph Gaston Patru | Bacteriostatic, fungistatic and algicidal compositions, particularly for submarine paints |
US4059098A (en) * | 1975-07-21 | 1977-11-22 | Stanford Research Institute | Flexible ultrasound coupling system |
US4101795A (en) * | 1976-10-25 | 1978-07-18 | Matsushita Electric Industrial Company | Ultrasonic probe |
US4213344A (en) * | 1978-10-16 | 1980-07-22 | Krautkramer-Branson, Incorporated | Method and apparatus for providing dynamic focussing and beam steering in an ultrasonic apparatus |
US4276491A (en) * | 1979-10-02 | 1981-06-30 | Ausonics Pty. Limited | Focusing piezoelectric ultrasonic medical diagnostic system |
US4315514A (en) * | 1980-05-08 | 1982-02-16 | William Drewes | Method and apparatus for selective cell destruction |
US4325381A (en) * | 1979-11-21 | 1982-04-20 | New York Institute Of Technology | Ultrasonic scanning head with reduced geometrical distortion |
US4343301A (en) * | 1979-10-04 | 1982-08-10 | Robert Indech | Subcutaneous neural stimulation or local tissue destruction |
US4381007A (en) * | 1981-04-30 | 1983-04-26 | The United States Of America As Represented By The United States Department Of Energy | Multipolar corneal-shaping electrode with flexible removable skirt |
US4381787A (en) * | 1980-08-15 | 1983-05-03 | Technicare Corporation | Ultrasound imaging system combining static B-scan and real-time sector scanning capability |
US4397314A (en) * | 1981-08-03 | 1983-08-09 | Clini-Therm Corporation | Method and apparatus for controlling and optimizing the heating pattern for a hyperthermia system |
US4409839A (en) * | 1981-07-01 | 1983-10-18 | Siemens Ag | Ultrasound camera |
US4441486A (en) * | 1981-10-27 | 1984-04-10 | Board Of Trustees Of Leland Stanford Jr. University | Hyperthermia system |
US4452084A (en) * | 1982-10-25 | 1984-06-05 | Sri International | Inherent delay line ultrasonic transducer and systems |
US4484569A (en) * | 1981-03-13 | 1984-11-27 | Riverside Research Institute | Ultrasonic diagnostic and therapeutic transducer assembly and method for using |
US4513749A (en) * | 1982-11-18 | 1985-04-30 | Board Of Trustees Of Leland Stanford University | Three-dimensional temperature probe |
US4527550A (en) * | 1983-01-28 | 1985-07-09 | The United States Of America As Represented By The Department Of Health And Human Services | Helical coil for diathermy apparatus |
US4528979A (en) * | 1982-03-18 | 1985-07-16 | Kievsky Nauchno-Issledovatelsky Institut Otolaringologii Imeni Professora A.S. Kolomiiobenka | Cryo-ultrasonic surgical instrument |
US4567895A (en) * | 1984-04-02 | 1986-02-04 | Advanced Technology Laboratories, Inc. | Fully wetted mechanical ultrasound scanhead |
US4586512A (en) * | 1981-06-26 | 1986-05-06 | Thomson-Csf | Device for localized heating of biological tissues |
US4601296A (en) * | 1983-10-07 | 1986-07-22 | Yeda Research And Development Co., Ltd. | Hyperthermia apparatus |
US4646756A (en) * | 1982-10-26 | 1987-03-03 | The University Of Aberdeen | Ultra sound hyperthermia device |
US4663358A (en) * | 1985-05-01 | 1987-05-05 | Biomaterials Universe, Inc. | Porous and transparent poly(vinyl alcohol) gel and method of manufacturing the same |
US4668516A (en) * | 1983-03-30 | 1987-05-26 | Alain Duraffourd | Composition for regenerating the collagen of connective skin tissue and a process for its preparation |
US4697588A (en) * | 1984-12-27 | 1987-10-06 | Siemens Aktiengesellschaft | Shock wave tube for the fragmentation of concrements |
US4757820A (en) * | 1985-03-15 | 1988-07-19 | Kabushiki Kaisha Toshiba | Ultrasound therapy system |
US4807633A (en) * | 1986-05-21 | 1989-02-28 | Indianapolis Center For Advanced Research | Non-invasive tissue thermometry system and method |
US4858613A (en) * | 1988-03-02 | 1989-08-22 | Laboratory Equipment, Corp. | Localization and therapy system for treatment of spatially oriented focal disease |
US4860732A (en) * | 1987-11-25 | 1989-08-29 | Olympus Optical Co., Ltd. | Endoscope apparatus provided with endoscope insertion aid |
US4865041A (en) * | 1987-02-04 | 1989-09-12 | Siemens Aktiengesellschaft | Lithotripter having an ultrasound locating system integrated therewith |
US4865042A (en) * | 1985-08-16 | 1989-09-12 | Hitachi, Ltd. | Ultrasonic irradiation system |
US4867169A (en) * | 1986-07-29 | 1989-09-19 | Kaoru Machida | Attachment attached to ultrasound probe for clinical application |
US4874562A (en) * | 1986-02-13 | 1989-10-17 | Biomaterials Universe, Inc. | Method of molding a polyvinyl alcohol contact lens |
US4875487A (en) * | 1986-05-02 | 1989-10-24 | Varian Associates, Inc. | Compressional wave hyperthermia treating method and apparatus |
US4893624A (en) * | 1988-06-21 | 1990-01-16 | Massachusetts Institute Of Technology | Diffuse focus ultrasound hyperthermia system |
US4917096A (en) * | 1987-11-25 | 1990-04-17 | Laboratory Equipment, Corp. | Portable ultrasonic probe |
US4938216A (en) * | 1988-06-21 | 1990-07-03 | Massachusetts Institute Of Technology | Mechanically scanned line-focus ultrasound hyperthermia system |
US4938217A (en) * | 1988-06-21 | 1990-07-03 | Massachusetts Institute Of Technology | Electronically-controlled variable focus ultrasound hyperthermia system |
US4947046A (en) * | 1988-05-27 | 1990-08-07 | Konica Corporation | Method for preparation of radiographic image conversion panel and radiographic image conversion panel thereby |
US4951653A (en) * | 1988-03-02 | 1990-08-28 | Laboratory Equipment, Corp. | Ultrasound brain lesioning system |
US4955365A (en) * | 1988-03-02 | 1990-09-11 | Laboratory Equipment, Corp. | Localization and therapy system for treatment of spatially oriented focal disease |
US4958626A (en) * | 1986-04-22 | 1990-09-25 | Nippon Oil Co., Ltd. | Method for applying electromagnetic wave and ultrasonic wave therapies |
US4973096A (en) * | 1989-08-21 | 1990-11-27 | Joyce Patrick H | Shoe transporting device |
US4976709A (en) * | 1988-12-15 | 1990-12-11 | Sand Bruce J | Method for collagen treatment |
US4979501A (en) * | 1987-05-19 | 1990-12-25 | Vissh Voennomedicinski Institut | Method and apparatus for medical treatment of the pathological state of bones |
US5012797A (en) * | 1990-01-08 | 1991-05-07 | Montefiore Hospital Association Of Western Pennsylvania | Method for removing skin wrinkles |
US5036855A (en) * | 1988-03-02 | 1991-08-06 | Laboratory Equipment, Corp. | Localization and therapy system for treatment of spatially oriented focal disease |
US5054470A (en) * | 1988-03-02 | 1991-10-08 | Laboratory Equipment, Corp. | Ultrasonic treatment transducer with pressurized acoustic coupling |
US5115814A (en) * | 1989-08-18 | 1992-05-26 | Intertherapy, Inc. | Intravascular ultrasonic imaging probe and methods of using same |
US5117832A (en) * | 1990-09-21 | 1992-06-02 | Diasonics, Inc. | Curved rectangular/elliptical transducer |
US5123418A (en) * | 1989-02-28 | 1992-06-23 | Centre National De La Recherche Scientifique-C.N.R.S | Micro-echographic probe for ultrasound collimation through a deformable surface |
US5143074A (en) * | 1983-12-14 | 1992-09-01 | Edap International | Ultrasonic treatment device using a focussing and oscillating piezoelectric element |
US5143063A (en) * | 1988-02-09 | 1992-09-01 | Fellner Donald G | Method of removing adipose tissue from the body |
US5150714A (en) * | 1991-05-10 | 1992-09-29 | Sri International | Ultrasonic inspection method and apparatus with audible output |
US5150711A (en) * | 1983-12-14 | 1992-09-29 | Edap International, S.A. | Ultra-high-speed extracorporeal ultrasound hyperthermia treatment device |
US5156144A (en) * | 1989-10-20 | 1992-10-20 | Olympus Optical Co., Ltd. | Ultrasonic wave therapeutic device |
US5158536A (en) * | 1989-08-28 | 1992-10-27 | Biopulmonics, Inc. | Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids |
US5163421A (en) * | 1988-01-22 | 1992-11-17 | Angiosonics, Inc. | In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging |
US5191880A (en) * | 1990-07-31 | 1993-03-09 | Mcleod Kenneth J | Method for the promotion of growth, ingrowth and healing of bone tissue and the prevention of osteopenia by mechanical loading of the bone tissue |
US5209720A (en) * | 1989-12-22 | 1993-05-11 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes |
US5224467A (en) * | 1991-10-30 | 1993-07-06 | Kabushiki Kaisha Machida Seisakusho | Endoscope with direction indication mechanism |
US5230334A (en) * | 1992-01-22 | 1993-07-27 | Summit Technology, Inc. | Method and apparatus for generating localized hyperthermia |
US5230338A (en) * | 1987-11-10 | 1993-07-27 | Allen George S | Interactive image-guided surgical system for displaying images corresponding to the placement of a surgical tool or the like |
US5265614A (en) * | 1988-08-30 | 1993-11-30 | Fujitsu Limited | Acoustic coupler |
US5267985A (en) * | 1993-02-11 | 1993-12-07 | Trancell, Inc. | Drug delivery by multiple frequency phonophoresis |
US5269297A (en) * | 1992-02-27 | 1993-12-14 | Angiosonics Inc. | Ultrasonic transmission apparatus |
US5282797A (en) * | 1989-05-30 | 1994-02-01 | Cyrus Chess | Method for treating cutaneous vascular lesions |
US5295484A (en) * | 1992-05-19 | 1994-03-22 | Arizona Board Of Regents For And On Behalf Of The University Of Arizona | Apparatus and method for intra-cardiac ablation of arrhythmias |
US5304169A (en) * | 1985-09-27 | 1994-04-19 | Laser Biotech, Inc. | Method for collagen shrinkage |
US5321520A (en) * | 1992-07-20 | 1994-06-14 | Automated Medical Access Corporation | Automated high definition/resolution image storage, retrieval and transmission system |
US5360268A (en) * | 1992-11-02 | 1994-11-01 | Nippon Soken Inc. | Ultrasonic temperature measuring apparatus |
US5371483A (en) * | 1993-12-20 | 1994-12-06 | Bhardwaj; Mahesh C. | High intensity guided ultrasound source |
US5370121A (en) * | 1992-09-07 | 1994-12-06 | Siemens Aktiengesellschaft | Method and apparatus for non-invasive measurement of a temperature change in a subject |
US5380280A (en) * | 1993-11-12 | 1995-01-10 | Peterson; Erik W. | Aspiration system having pressure-controlled and flow-controlled modes |
US5419327A (en) * | 1992-12-07 | 1995-05-30 | Siemens Aktiengesellschaft | Acoustic therapy means |
US5435311A (en) * | 1989-06-27 | 1995-07-25 | Hitachi, Ltd. | Ultrasound therapeutic system |
US5458596A (en) * | 1994-05-06 | 1995-10-17 | Dorsal Orthopedic Corporation | Method and apparatus for controlled contraction of soft tissue |
US5460595A (en) * | 1993-06-01 | 1995-10-24 | Dynatronics Laser Corporation | Multi-frequency ultrasound therapy systems and methods |
US5471488A (en) * | 1994-04-05 | 1995-11-28 | International Business Machines Corporation | Clock fault detection circuit |
US5487388A (en) * | 1994-11-01 | 1996-01-30 | Interspec. Inc. | Three dimensional ultrasonic scanning devices and techniques |
US5492126A (en) * | 1994-05-02 | 1996-02-20 | Focal Surgery | Probe for medical imaging and therapy using ultrasound |
US5496256A (en) * | 1994-06-09 | 1996-03-05 | Sonex International Corporation | Ultrasonic bone healing device for dental application |
US5501655A (en) * | 1992-03-31 | 1996-03-26 | Massachusetts Institute Of Technology | Apparatus and method for acoustic heat generation and hyperthermia |
US5503320A (en) * | 1993-08-19 | 1996-04-02 | United States Surgical Corporation | Surgical apparatus with indicator |
US5507790A (en) * | 1994-03-21 | 1996-04-16 | Weiss; William V. | Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism |
US5520188A (en) * | 1994-11-02 | 1996-05-28 | Focus Surgery Inc. | Annular array transducer |
US5522869A (en) * | 1994-05-17 | 1996-06-04 | Burdette; Everette C. | Ultrasound device for use in a thermotherapy apparatus |
US5524620A (en) * | 1991-11-12 | 1996-06-11 | November Technologies Ltd. | Ablation of blood thrombi by means of acoustic energy |
US5524624A (en) * | 1994-05-05 | 1996-06-11 | Amei Technologies Inc. | Apparatus and method for stimulating tissue growth with ultrasound |
US5526812A (en) * | 1993-06-21 | 1996-06-18 | General Electric Company | Display system for enhancing visualization of body structures during medical procedures |
US6315741B1 (en) * | 1997-10-31 | 2001-11-13 | Roy W. Martin | Method and apparatus for medical procedures using high-intensity focused ultrasound |
US6413254B1 (en) * | 2000-01-19 | 2002-07-02 | Medtronic Xomed, Inc. | Method of tongue reduction by thermal ablation using high intensity focused ultrasound |
US20030176790A1 (en) * | 2000-12-28 | 2003-09-18 | Guided Therapy Systems, Inc. | Visual imaging system for ultrasonic probe |
US6623430B1 (en) * | 1997-10-14 | 2003-09-23 | Guided Therapy Systems, Inc. | Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system |
US20040267252A1 (en) * | 2003-06-30 | 2004-12-30 | Ethicon, Inc. | Multi-modality ablation device |
US20050154332A1 (en) * | 2004-01-12 | 2005-07-14 | Onda | Methods and systems for removing hair using focused acoustic energy |
Family Cites Families (814)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1004618A (en) | 1911-01-21 | 1911-10-03 | Joseph J Bennett | Trolley-head. |
US2427348A (en) | 1941-08-19 | 1947-09-16 | Bell Telephone Labor Inc | Piezoelectric vibrator |
US2792829A (en) | 1952-02-06 | 1957-05-21 | Raytheon Mfg Co | Frequency modulated ultrasonic therapeutic apparatus |
JPS5343987A (en) | 1976-09-30 | 1978-04-20 | Tokyo Shibaura Electric Co | Ultrasonic diagnostic device |
AT353506B (en) | 1976-10-19 | 1979-11-26 | List Hans | PIEZOELECTRIC RESONATOR |
US4211949A (en) | 1978-11-08 | 1980-07-08 | General Electric Company | Wear plate for piezoelectric ultrasonic transducer arrays |
US4211948A (en) | 1978-11-08 | 1980-07-08 | General Electric Company | Front surface matched piezoelectric ultrasonic transducer array with wide field of view |
JPS5686121A (en) | 1979-12-14 | 1981-07-13 | Teijin Ltd | Antitumor proten complex and its preparation |
US4372296A (en) | 1980-11-26 | 1983-02-08 | Fahim Mostafa S | Treatment of acne and skin disorders and compositions therefor |
JPS6336171Y2 (en) | 1981-03-12 | 1988-09-26 | ||
US4622972A (en) | 1981-10-05 | 1986-11-18 | Varian Associates, Inc. | Ultrasound hyperthermia applicator with variable coherence by multi-spiral focusing |
DE3300121A1 (en) | 1982-01-07 | 1983-07-14 | Technicare Corp., 80112 Englewood, Col. | METHOD AND DEVICE FOR IMAGING AND THERMALLY TREATING TISSUE BY MEANS OF ULTRASOUND |
US4431008A (en) | 1982-06-24 | 1984-02-14 | Wanner James F | Ultrasonic measurement system using a perturbing field, multiple sense beams and receivers |
US4534221A (en) | 1982-09-27 | 1985-08-13 | Technicare Corporation | Ultrasonic diagnostic imaging systems for varying depths of field |
US4507582A (en) | 1982-09-29 | 1985-03-26 | New York Institute Of Technology | Matching region for damped piezoelectric ultrasonic apparatus |
JPH064074B2 (en) | 1983-02-14 | 1994-01-19 | 株式会社日立製作所 | Ultrasonic diagnostic device and sound velocity measuring method using the same |
EP0142215A3 (en) | 1983-05-26 | 1987-03-11 | Advanced Technology Laboratories, Inc. | Ultrasound transducer with improved vibrational modes |
US4900540A (en) | 1983-06-20 | 1990-02-13 | Trustees Of The University Of Massachusetts | Lipisomes containing gas for ultrasound detection |
DE3476132D1 (en) | 1983-06-23 | 1989-02-16 | Matsushita Electric Ind Co Ltd | Ultrasonic probe having dual-motion transducer |
FR2551611B1 (en) | 1983-08-31 | 1986-10-24 | Labo Electronique Physique | NOVEL ULTRASONIC TRANSDUCER STRUCTURE AND ULTRASONIC ECHOGRAPHY MEDIA EXAMINATION APPARATUS COMPRISING SUCH A STRUCTURE |
US4513750A (en) | 1984-02-22 | 1985-04-30 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Method for thermal monitoring subcutaneous tissue |
US4620546A (en) | 1984-06-30 | 1986-11-04 | Kabushiki Kaisha Toshiba | Ultrasound hyperthermia apparatus |
DE3501808A1 (en) | 1985-01-21 | 1986-07-24 | Siemens AG, 1000 Berlin und 8000 München | ULTRASONIC CONVERTER |
DE3611669A1 (en) | 1985-04-10 | 1986-10-16 | Hitachi Medical Corp., Tokio/Tokyo | ULTRASONIC CONVERTER |
DE3650004T2 (en) | 1985-05-20 | 1995-02-23 | Matsushita Electric Ind Co Ltd | Ultrasound probe. |
US5054310A (en) | 1985-09-13 | 1991-10-08 | The California Province Of The Society Of Jesus | Test object and method of measurement of an ultrasonic beam |
US4817615A (en) | 1985-12-13 | 1989-04-04 | Matsushita Electric Industrial Co., Ltd. | Ultrasonic temperature measurement apparatus |
JPS62258597A (en) | 1986-04-25 | 1987-11-11 | Yokogawa Medical Syst Ltd | Ultrasonic transducer |
US4803625A (en) | 1986-06-30 | 1989-02-07 | Buddy Systems, Inc. | Personal health monitor |
JPS6336171A (en) | 1986-07-29 | 1988-02-16 | Toshiba Corp | Ultrasonic coupler |
US4801459A (en) | 1986-08-05 | 1989-01-31 | Liburdy Robert P | Technique for drug and chemical delivery |
JPS63122923A (en) | 1986-11-13 | 1988-05-26 | Agency Of Ind Science & Technol | Ultrasonic thermometric apparatus |
JPS63220847A (en) | 1987-03-10 | 1988-09-14 | 松下電器産業株式会社 | Ultrasonic probe |
US5178135A (en) | 1987-04-16 | 1993-01-12 | Olympus Optical Co., Ltd. | Therapeutical apparatus of extracorporeal type |
US4891043A (en) | 1987-05-28 | 1990-01-02 | Board Of Trustees Of The University Of Illinois | System for selective release of liposome encapsulated material via laser radiation |
JPH0348299Y2 (en) | 1987-05-29 | 1991-10-15 | ||
USD306965S (en) | 1987-09-04 | 1990-04-03 | Mark Jaworski | Dispenser for soap, lotions, or condiments |
US4932414A (en) | 1987-11-02 | 1990-06-12 | Cornell Research Foundation, Inc. | System of therapeutic ultrasound and real-time ultrasonic scanning |
US5040537A (en) | 1987-11-24 | 1991-08-20 | Hitachi, Ltd. | Method and apparatus for the measurement and medical treatment using an ultrasonic wave |
US5251127A (en) | 1988-02-01 | 1993-10-05 | Faro Medical Technologies Inc. | Computer-aided surgery apparatus |
US5665141A (en) | 1988-03-30 | 1997-09-09 | Arjo Hospital Equipment Ab | Ultrasonic treatment process |
JP2615132B2 (en) | 1988-05-19 | 1997-05-28 | 富士通株式会社 | Ultrasonic probe |
US4966953A (en) | 1988-06-02 | 1990-10-30 | Takiron Co., Ltd. | Liquid segment polyurethane gel and couplers for ultrasonic diagnostic probe comprising the same |
US5018508A (en) | 1988-06-03 | 1991-05-28 | Fry Francis J | System and method using chemicals and ultrasound or ultrasound alone to replace more conventional surgery |
US4896673A (en) | 1988-07-15 | 1990-01-30 | Medstone International, Inc. | Method and apparatus for stone localization using ultrasound imaging |
US5054491A (en) | 1988-10-17 | 1991-10-08 | Olympus Optical Co., Ltd. | Ultrasonic endoscope apparatus |
US5159931A (en) | 1988-11-25 | 1992-11-03 | Riccardo Pini | Apparatus for obtaining a three-dimensional reconstruction of anatomic structures through the acquisition of echographic images |
EP0390311B1 (en) | 1989-03-27 | 1994-12-28 | Kabushiki Kaisha Toshiba | Mechanical ultrasonic scanner |
JP2745147B2 (en) | 1989-03-27 | 1998-04-28 | 三菱マテリアル 株式会社 | Piezoelectric transducer |
DE3914619A1 (en) | 1989-05-03 | 1990-11-08 | Kontron Elektronik | DEVICE FOR TRANSOESOPHAGEAL ECHOCARDIOGRAPHY |
US6016255A (en) | 1990-11-19 | 2000-01-18 | Dallas Semiconductor Corp. | Portable data carrier mounting system |
US5212671A (en) | 1989-06-22 | 1993-05-18 | Terumo Kabushiki Kaisha | Ultrasonic probe having backing material layer of uneven thickness |
JPH03123559A (en) | 1989-10-09 | 1991-05-27 | Ya Man Ltd | Ultrasonic beauty apparatus |
US5240003A (en) | 1989-10-16 | 1993-08-31 | Du-Med B.V. | Ultrasonic instrument with a micro motor having stator coils on a flexible circuit board |
JPH03136642A (en) | 1989-10-20 | 1991-06-11 | Olympus Optical Co Ltd | Ultrasonic treatment device |
DE69019289T2 (en) | 1989-10-27 | 1996-02-01 | Storz Instr Co | Method for driving an ultrasonic transducer. |
US5070879A (en) | 1989-11-30 | 1991-12-10 | Acoustic Imaging Technologies Corp. | Ultrasound imaging method and apparatus |
CA2032204C (en) | 1989-12-14 | 1995-03-14 | Takashi Mochizuki | Three-dimensional ultrasonic scanner |
US5149319A (en) | 1990-09-11 | 1992-09-22 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids |
US5580575A (en) | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
US5305757A (en) | 1989-12-22 | 1994-04-26 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
US5469854A (en) | 1989-12-22 | 1995-11-28 | Imarx Pharmaceutical Corp. | Methods of preparing gas-filled liposomes |
JP3015481B2 (en) | 1990-03-28 | 2000-03-06 | 株式会社東芝 | Ultrasonic probe system |
IN172208B (en) | 1990-04-02 | 1993-05-01 | Sint Sa | |
JPH03297475A (en) | 1990-04-16 | 1991-12-27 | Ken Ishihara | Controlling method for emission of medicine by means of resonance sound wave |
US5205287A (en) | 1990-04-26 | 1993-04-27 | Hoechst Aktiengesellschaft | Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents |
DE4117638A1 (en) | 1990-05-30 | 1991-12-05 | Toshiba Kawasaki Kk | SHOCK WAVE GENERATOR WITH A PIEZOELECTRIC ELEMENT |
US5215680A (en) | 1990-07-10 | 1993-06-01 | Cavitation-Control Technology, Inc. | Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles |
JP3044054B2 (en) | 1990-07-31 | 2000-05-22 | ヤーマン株式会社 | Ultrasonic beauty device with variable contact temperature |
US5174929A (en) | 1990-08-31 | 1992-12-29 | Ciba-Geigy Corporation | Preparation of stable polyvinyl alcohol hydrogel contact lens |
DE4029175C2 (en) | 1990-09-13 | 1993-10-28 | Lauerer Friedrich | Electrical protection device |
SE501045C2 (en) | 1990-09-17 | 1994-10-24 | Roofer Int Ab | Method of laying roofing board and device for carrying out the procedure |
JPH04150847A (en) | 1990-10-12 | 1992-05-25 | Katsuya Takasu | Armpit smell surgical apparatus and chip for operation |
US5685820A (en) | 1990-11-06 | 1997-11-11 | Partomed Medizintechnik Gmbh | Instrument for the penetration of body tissue |
GB9025431D0 (en) | 1990-11-22 | 1991-01-09 | Advanced Tech Lab | Three dimensional ultrasonic imaging |
US5997497A (en) | 1991-01-11 | 1999-12-07 | Advanced Cardiovascular Systems | Ultrasound catheter having integrated drug delivery system and methods of using same |
US5957882A (en) | 1991-01-11 | 1999-09-28 | Advanced Cardiovascular Systems, Inc. | Ultrasound devices for ablating and removing obstructive matter from anatomical passageways and blood vessels |
FR2672486A1 (en) | 1991-02-11 | 1992-08-14 | Technomed Int Sa | Ultrasound apparatus for extracorporeal therapeutic treatment of superficial varicose veins |
FR2679125B1 (en) | 1991-07-19 | 1993-11-26 | Technomed International | USE OF AT LEAST ONE COMPOSITE PIEZOELECTRIC TRANSDUCER FOR THE MANUFACTURE OF AN ULTRASONIC THERAPY APPARATUS FOR THERAPY IN PARTICULAR OF CONCRETIONS, FABRICS OR BONES OF A LIVING BEING. |
US5255681A (en) | 1991-03-20 | 1993-10-26 | Olympus Optical Co., Ltd. | Ultrasonic wave diagnosing apparatus having an ultrasonic wave transmitting and receiving part transmitting and receiving ultrasonic waves |
DE69208141T2 (en) | 1991-04-15 | 1996-07-18 | Toshiba Kawasaki Kk | Device for destroying concretions |
US5429582A (en) | 1991-06-14 | 1995-07-04 | Williams; Jeffery A. | Tumor treatment |
JP3123559B2 (en) | 1991-06-29 | 2001-01-15 | 東芝ライテック株式会社 | Lighting equipment |
US5383917A (en) * | 1991-07-05 | 1995-01-24 | Jawahar M. Desai | Device and method for multi-phase radio-frequency ablation |
US5327895A (en) | 1991-07-10 | 1994-07-12 | Kabushiki Kaisha Toshiba | Ultrasonic probe and ultrasonic diagnosing system using ultrasonic probe |
US5704361A (en) | 1991-11-08 | 1998-01-06 | Mayo Foundation For Medical Education And Research | Volumetric image ultrasound transducer underfluid catheter system |
US5329202A (en) | 1991-11-22 | 1994-07-12 | Advanced Imaging Systems | Large area ultrasonic transducer |
US5601526A (en) | 1991-12-20 | 1997-02-11 | Technomed Medical Systems | Ultrasound therapy apparatus delivering ultrasound waves having thermal and cavitation effects |
FR2685872A1 (en) | 1992-01-07 | 1993-07-09 | Edap Int | APPARATUS OF EXTRACORPOREAL ULTRASONIC HYPERTHERMIA WITH VERY HIGH POWER AND ITS OPERATING METHOD. |
WO1993016641A1 (en) | 1992-02-21 | 1993-09-02 | Diasonics, Inc. | Ultrasound intracavity system for imaging therapy planning and treatment of focal disease |
JP3386488B2 (en) | 1992-03-10 | 2003-03-17 | 株式会社東芝 | Ultrasound therapy equipment |
US5690608A (en) | 1992-04-08 | 1997-11-25 | Asec Co., Ltd. | Ultrasonic apparatus for health and beauty |
US5257970A (en) | 1992-04-09 | 1993-11-02 | Health Research, Inc. | In situ photodynamic therapy |
JPH0773576B2 (en) | 1992-05-27 | 1995-08-09 | アロカ株式会社 | Ultrasonic probe for 3D data acquisition |
JP3257640B2 (en) | 1992-06-09 | 2002-02-18 | オリンパス光学工業株式会社 | Stereoscopic endoscope device |
WO1994006380A1 (en) | 1992-09-16 | 1994-03-31 | Hitachi, Ltd. | Ultrasonic irradiation apparatus and processor using the same |
US5626631A (en) | 1992-10-20 | 1997-05-06 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5391197A (en) | 1992-11-13 | 1995-02-21 | Dornier Medical Systems, Inc. | Ultrasound thermotherapy probe |
US5620479A (en) | 1992-11-13 | 1997-04-15 | The Regents Of The University Of California | Method and apparatus for thermal therapy of tumors |
US6537306B1 (en) | 1992-11-13 | 2003-03-25 | The Regents Of The University Of California | Method of manufacture of a transurethral ultrasound applicator for prostate gland thermal therapy |
US5370122A (en) | 1992-11-18 | 1994-12-06 | Kunig; Horst E. | Method and apparatus for measuring myocardial impairment, dysfunctions, sufficiency, and insufficiency |
JP3272792B2 (en) | 1992-12-15 | 2002-04-08 | フクダ電子株式会社 | Ultrasonic coupler manufacturing method |
US5573497A (en) | 1994-11-30 | 1996-11-12 | Technomed Medical Systems And Institut National | High-intensity ultrasound therapy method and apparatus with controlled cavitation effect and reduced side lobes |
FR2717942B1 (en) | 1994-03-01 | 1996-05-31 | Technomed Int Sa | Method and apparatus for therapy generating high intensity ultrasound with controlled cavitation effect. |
DE4302538C1 (en) | 1993-01-29 | 1994-04-07 | Siemens Ag | Ultrasonic therapy device for tumour treatment lithotripsy or osteorestoration - with ultrasonic imaging and ultrasonic treatment modes using respective acoustic wave frequencies |
US5423220A (en) | 1993-01-29 | 1995-06-13 | Parallel Design | Ultrasonic transducer array and manufacturing method thereof |
DE4302537C1 (en) | 1993-01-29 | 1994-04-28 | Siemens Ag | Ultrasound imaging and therapy device - generates imaging waves and focussed treatment waves having two differing frequencies for location and treatment of e.g tumours |
US5453575A (en) | 1993-02-01 | 1995-09-26 | Endosonics Corporation | Apparatus and method for detecting blood flow in intravascular ultrasonic imaging |
DE69431741T2 (en) | 1993-03-12 | 2003-09-11 | Toshiba Kawasaki Kk | Device for medical treatment with ultrasound |
US5307812A (en) | 1993-03-26 | 1994-05-03 | General Electric Company | Heat surgery system monitored by real-time magnetic resonance profiling |
DE4310924C2 (en) | 1993-04-02 | 1995-01-26 | Siemens Ag | Therapy device for the treatment of pathological tissue with ultrasound waves and a catheter |
US5305756A (en) | 1993-04-05 | 1994-04-26 | Advanced Technology Laboratories, Inc. | Volumetric ultrasonic imaging with diverging elevational ultrasound beams |
US5817021A (en) | 1993-04-15 | 1998-10-06 | Siemens Aktiengesellschaft | Therapy apparatus for treating conditions of the heart and heart-proximate vessels |
CA2161430C (en) | 1993-04-26 | 2001-07-03 | Richard D. Bucholz | System and method for indicating the position of a surgical probe |
DE4318237A1 (en) | 1993-06-01 | 1994-12-08 | Storz Medical Ag | Device for the treatment of biological tissue and body concretions |
US5392259A (en) | 1993-06-15 | 1995-02-21 | Bolorforosh; Mir S. S. | Micro-grooves for the design of wideband clinical ultrasonic transducers |
US5398689A (en) | 1993-06-16 | 1995-03-21 | Hewlett-Packard Company | Ultrasonic probe assembly and cable therefor |
US5413550A (en) | 1993-07-21 | 1995-05-09 | Pti, Inc. | Ultrasound therapy system with automatic dose control |
DE69414121T2 (en) | 1993-07-26 | 1999-06-10 | Technomed Medical Systems | ENDOSCOPIC PROBE FOR IMAGING AND THERAPY AND YOUR TREATMENT SYSTEM |
JP2998505B2 (en) | 1993-07-29 | 2000-01-11 | 富士写真光機株式会社 | Radial ultrasonic scanner |
US5792058A (en) | 1993-09-07 | 1998-08-11 | Acuson Corporation | Broadband phased array transducer with wide bandwidth, high sensitivity and reduced cross-talk and method for manufacture thereof |
US5438998A (en) | 1993-09-07 | 1995-08-08 | Acuson Corporation | Broadband phased array transducer design with frequency controlled two dimension capability and methods for manufacture thereof |
JPH0780087A (en) | 1993-09-16 | 1995-03-28 | Aaku Techno Res Kk | Face wrinkle remover |
US5379773A (en) | 1993-09-17 | 1995-01-10 | Hornsby; James J. | Echographic suction cannula and electronics therefor |
US5661235A (en) | 1993-10-01 | 1997-08-26 | Hysitron Incorporated | Multi-dimensional capacitive transducer |
US20050288748A1 (en) | 1993-10-04 | 2005-12-29 | Huan-Chen Li | Medical device for treating skin problems |
IL107523A (en) | 1993-11-07 | 2000-01-31 | Ultraguide Ltd | Articulated needle guide for ultrasound imaging and method of using same |
US5526814A (en) | 1993-11-09 | 1996-06-18 | General Electric Company | Automatically positioned focussed energy system guided by medical imaging |
US5445611A (en) | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
US5814599A (en) | 1995-08-04 | 1998-09-29 | Massachusetts Insitiute Of Technology | Transdermal delivery of encapsulated drugs |
US20020169394A1 (en) | 1993-11-15 | 2002-11-14 | Eppstein Jonathan A. | Integrated tissue poration, fluid harvesting and analysis device, and method therefor |
US5609562A (en) | 1993-11-16 | 1997-03-11 | Worldwide Optical Trocar Licensing Corporation | Visually directed trocar and method |
JPH07136162A (en) | 1993-11-17 | 1995-05-30 | Fujitsu Ltd | Ultrasonic coupler |
US5842473A (en) | 1993-11-29 | 1998-12-01 | Life Imaging Systems | Three-dimensional imaging system |
US5471988A (en) | 1993-12-24 | 1995-12-05 | Olympus Optical Co., Ltd. | Ultrasonic diagnosis and therapy system in which focusing point of therapeutic ultrasonic wave is locked at predetermined position within observation ultrasonic scanning range |
EP0659387B1 (en) | 1993-12-24 | 2003-04-16 | Olympus Optical Co., Ltd. | Ultrasonic diagnosis and therapy system in which focusing point of therapeutic ultrasonic wave is locked at predetermined position within observation ultrasonic scanning range |
JPH07184907A (en) | 1993-12-28 | 1995-07-25 | Toshiba Corp | Ultrasonic treating device |
DE4443947B4 (en) | 1994-01-14 | 2005-09-22 | Siemens Ag | endoscope |
FR2715313B1 (en) | 1994-01-27 | 1996-05-31 | Edap Int | Method for controlling a hyperthermia treatment device using ultrasound. |
JP3378336B2 (en) | 1994-02-08 | 2003-02-17 | 株式会社アバン | Beauty equipment |
AU1889595A (en) | 1994-03-07 | 1995-09-25 | Medisonic A/S | Apparatus for non-invasive tissue destruction by means of ultrasound |
US5511296A (en) | 1994-04-08 | 1996-04-30 | Hewlett Packard Company | Method for making integrated matching layer for ultrasonic transducers |
AU2373695A (en) | 1994-05-03 | 1995-11-29 | Board Of Regents, The University Of Texas System | Apparatus and method for noninvasive doppler ultrasound-guided real-time control of tissue damage in thermal therapy |
US5396143A (en) | 1994-05-20 | 1995-03-07 | Hewlett-Packard Company | Elevation aperture control of an ultrasonic transducer |
US5575807A (en) | 1994-06-10 | 1996-11-19 | Zmd Corporation | Medical device power supply with AC disconnect alarm and method of supplying power to a medical device |
US5560362A (en) | 1994-06-13 | 1996-10-01 | Acuson Corporation | Active thermal control of ultrasound transducers |
US5540235A (en) | 1994-06-30 | 1996-07-30 | Wilson; John R. | Adaptor for neurophysiological monitoring with a personal computer |
FR2722358B1 (en) | 1994-07-08 | 1996-08-14 | Thomson Csf | BROADBAND MULTI-FREQUENCY ACOUSTIC TRANSDUCER |
NO300407B1 (en) | 1994-08-30 | 1997-05-26 | Vingmed Sound As | Apparatus for endoscope or gastroscope examination of patients |
US5829444A (en) | 1994-09-15 | 1998-11-03 | Visualization Technology, Inc. | Position tracking and imaging system for use in medical applications |
US5694936A (en) | 1994-09-17 | 1997-12-09 | Kabushiki Kaisha Toshiba | Ultrasonic apparatus for thermotherapy with variable frequency for suppressing cavitation |
US5443068A (en) | 1994-09-26 | 1995-08-22 | General Electric Company | Mechanical positioner for magnetic resonance guided ultrasound therapy |
US5810009A (en) | 1994-09-27 | 1998-09-22 | Kabushiki Kaisha Toshiba | Ultrasonic probe, ultrasonic probe device having the ultrasonic probe, and method of manufacturing the ultrasonic probe |
US5503152A (en) | 1994-09-28 | 1996-04-02 | Tetrad Corporation | Ultrasonic transducer assembly and method for three-dimensional imaging |
US5577507A (en) | 1994-11-21 | 1996-11-26 | General Electric Company | Compound lens for ultrasound transducer probe |
DE4446429C1 (en) | 1994-12-23 | 1996-08-22 | Siemens Ag | Device for treating an object with focused ultrasound waves |
US5999843A (en) | 1995-01-03 | 1999-12-07 | Omnicorder Technologies, Inc. | Detection of cancerous lesions by their effect on the spatial homogeneity of skin temperature |
US5626554A (en) | 1995-02-21 | 1997-05-06 | Exogen, Inc. | Gel containment structure |
US6019724A (en) | 1995-02-22 | 2000-02-01 | Gronningsaeter; Aage | Method for ultrasound guidance during clinical procedures |
DE19609034C2 (en) | 1995-03-10 | 1998-03-05 | Karlsruhe Forschzent | Device for guiding surgical instruments for endoscopic surgery |
US6246898B1 (en) | 1995-03-28 | 2001-06-12 | Sonometrics Corporation | Method for carrying out a medical procedure using a three-dimensional tracking and imaging system |
US5658328A (en) | 1995-03-30 | 1997-08-19 | Johnson; Gerald W. | Endoscopic assisted mastopexy |
US5899861A (en) | 1995-03-31 | 1999-05-04 | Siemens Medical Systems, Inc. | 3-dimensional volume by aggregating ultrasound fields of view |
US5984881A (en) | 1995-03-31 | 1999-11-16 | Kabushiki Kaisha Toshiba | Ultrasound therapeutic apparatus using a therapeutic ultrasonic wave source and an ultrasonic probe |
US5655535A (en) | 1996-03-29 | 1997-08-12 | Siemens Medical Systems, Inc. | 3-Dimensional compound ultrasound field of view |
US5873902A (en) | 1995-03-31 | 1999-02-23 | Focus Surgery, Inc. | Ultrasound intensity determining method and apparatus |
US5924989A (en) | 1995-04-03 | 1999-07-20 | Polz; Hans | Method and device for capturing diagnostically acceptable three-dimensional ultrasound image data records |
US5644085A (en) | 1995-04-03 | 1997-07-01 | General Electric Company | High density integrated ultrasonic phased array transducer and a method for making |
US5577502A (en) | 1995-04-03 | 1996-11-26 | General Electric Company | Imaging of interventional devices during medical procedures |
US5701900A (en) | 1995-05-01 | 1997-12-30 | Cedars-Sinai Medical Center | Ultrasonic transducer orientation sensing and display apparatus and method |
US5735280A (en) | 1995-05-02 | 1998-04-07 | Heart Rhythm Technologies, Inc. | Ultrasound energy delivery system and method |
US5660836A (en) | 1995-05-05 | 1997-08-26 | Knowlton; Edward W. | Method and apparatus for controlled contraction of collagen tissue |
US5755753A (en) | 1995-05-05 | 1998-05-26 | Thermage, Inc. | Method for controlled contraction of collagen tissue |
US6430446B1 (en) | 1995-05-05 | 2002-08-06 | Thermage, Inc. | Apparatus for tissue remodeling |
US6425912B1 (en) * | 1995-05-05 | 2002-07-30 | Thermage, Inc. | Method and apparatus for modifying skin surface and soft tissue structure |
US6241753B1 (en) | 1995-05-05 | 2001-06-05 | Thermage, Inc. | Method for scar collagen formation and contraction |
US5558092A (en) | 1995-06-06 | 1996-09-24 | Imarx Pharmaceutical Corp. | Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously |
US5605154A (en) | 1995-06-06 | 1997-02-25 | Duke University | Two-dimensional phase correction using a deformable ultrasonic transducer array |
US5755228A (en) | 1995-06-07 | 1998-05-26 | Hologic, Inc. | Equipment and method for calibration and quality assurance of an ultrasonic bone anaylsis apparatus |
WO1997000482A1 (en) | 1995-06-15 | 1997-01-03 | The Regents Of The University Of Michigan | Method and apparatus for composition and display of three-dimensional image from two-dimensional ultrasound |
US5655538A (en) | 1995-06-19 | 1997-08-12 | General Electric Company | Ultrasonic phased array transducer with an ultralow impedance backfill and a method for making |
US6248073B1 (en) | 1995-06-29 | 2001-06-19 | Teratech Corporation | Ultrasound scan conversion with spatial dithering |
US6216029B1 (en) | 1995-07-16 | 2001-04-10 | Ultraguide Ltd. | Free-hand aiming of a needle guide |
US5706564A (en) | 1995-07-27 | 1998-01-13 | General Electric Company | Method for designing ultrasonic transducers using constraints on feasibility and transitional Butterworth-Thompson spectrum |
DE19528754A1 (en) | 1995-08-04 | 1997-02-06 | Trw Repa Gmbh | Airbag restraint module |
JPH0947458A (en) | 1995-08-09 | 1997-02-18 | Toshiba Corp | Ultrasonic therapeupic device and applicator |
US5638819A (en) | 1995-08-29 | 1997-06-17 | Manwaring; Kim H. | Method and apparatus for guiding an instrument to a target |
US5662116A (en) | 1995-09-12 | 1997-09-02 | Fuji Photo Optical Co., Ltd. | Multi-plane electronic scan ultrasound probe |
US5964749A (en) | 1995-09-15 | 1999-10-12 | Esc Medical Systems Ltd. | Method and apparatus for skin rejuvenation and wrinkle smoothing |
US5622175A (en) | 1995-09-29 | 1997-04-22 | Hewlett-Packard Company | Miniaturization of a rotatable sensor |
US5615091A (en) | 1995-10-11 | 1997-03-25 | Biochem International, Inc. | Isolation transformer for medical equipment |
JP2741493B2 (en) | 1995-10-18 | 1998-04-15 | 勝男 曽我 | Ultrasonic diffusion oscillator for beauty |
US5618275A (en) | 1995-10-27 | 1997-04-08 | Sonex International Corporation | Ultrasonic method and apparatus for cosmetic and dermatological applications |
WO1997017018A1 (en) | 1995-11-09 | 1997-05-15 | Brigham & Women's Hospital | Aperiodic ultrasound phased array |
US5895356A (en) | 1995-11-15 | 1999-04-20 | American Medical Systems, Inc. | Apparatus and method for transurethral focussed ultrasound therapy |
US7115123B2 (en) | 1996-01-05 | 2006-10-03 | Thermage, Inc. | Handpiece with electrode and non-volatile memory |
US7006874B2 (en) | 1996-01-05 | 2006-02-28 | Thermage, Inc. | Treatment apparatus with electromagnetic energy delivery device and non-volatile memory |
US6350276B1 (en) | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
US20040000316A1 (en) | 1996-01-05 | 2004-01-01 | Knowlton Edward W. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US20030212393A1 (en) | 1996-01-05 | 2003-11-13 | Knowlton Edward W. | Handpiece with RF electrode and non-volatile memory |
US7189230B2 (en) | 1996-01-05 | 2007-03-13 | Thermage, Inc. | Method for treating skin and underlying tissue |
US7473251B2 (en) | 1996-01-05 | 2009-01-06 | Thermage, Inc. | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient |
US5715823A (en) | 1996-02-27 | 1998-02-10 | Atlantis Diagnostics International, L.L.C. | Ultrasonic diagnostic imaging system with universal access to diagnostic information and images |
US5603323A (en) | 1996-02-27 | 1997-02-18 | Advanced Technology Laboratories, Inc. | Medical ultrasonic diagnostic system with upgradeable transducer probes and other features |
EP0883860B1 (en) | 1996-02-29 | 2006-08-23 | Acuson Corporation | Multiple ultrasound image registration system, method and transducer |
US6190323B1 (en) | 1996-03-13 | 2001-02-20 | Agielnt Technologies | Direct contact scanner and related method |
US5817013A (en) | 1996-03-19 | 1998-10-06 | Enable Medical Corporation | Method and apparatus for the minimally invasive harvesting of a saphenous vein and the like |
US5676692A (en) | 1996-03-28 | 1997-10-14 | Indianapolis Center For Advanced Research, Inc. | Focussed ultrasound tissue treatment method |
US5673699A (en) | 1996-05-31 | 1997-10-07 | Duke University | Method and apparatus for abberation correction in the presence of a distributed aberrator |
US5749364A (en) | 1996-06-21 | 1998-05-12 | Acuson Corporation | Method and apparatus for mapping pressure and tissue properties |
US5746762A (en) | 1996-06-24 | 1998-05-05 | Bass; Lawrence S. | Device and method for surgical flap dissection |
JP2002515786A (en) | 1996-06-28 | 2002-05-28 | ソントラ メディカル,エル.ピー. | Ultrasound enhancement of transdermal delivery |
US5671746A (en) | 1996-07-29 | 1997-09-30 | Acuson Corporation | Elevation steerable ultrasound transducer array |
US5763886A (en) | 1996-08-07 | 1998-06-09 | Northrop Grumman Corporation | Two-dimensional imaging backscatter probe |
US5971949A (en) | 1996-08-19 | 1999-10-26 | Angiosonics Inc. | Ultrasound transmission apparatus and method of using same |
US5984882A (en) | 1996-08-19 | 1999-11-16 | Angiosonics Inc. | Methods for prevention and treatment of cancer and other proliferative diseases with ultrasonic energy |
US6605041B2 (en) | 1996-08-22 | 2003-08-12 | Synthes (U.S.A.) | 3-D ultrasound recording device |
DE59712045D1 (en) | 1996-08-22 | 2004-12-02 | Storz Medical Ag Kreuzlingen | DEVICE FOR TREATING THE HEART |
US5844140A (en) | 1996-08-27 | 1998-12-01 | Seale; Joseph B. | Ultrasound beam alignment servo |
DE19635593C1 (en) | 1996-09-02 | 1998-04-23 | Siemens Ag | Ultrasound transducer for diagnostic and therapeutic use |
US5795297A (en) | 1996-09-12 | 1998-08-18 | Atlantis Diagnostics International, L.L.C. | Ultrasonic diagnostic imaging system with personal computer architecture |
US5727554A (en) | 1996-09-19 | 1998-03-17 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Apparatus responsive to movement of a patient during treatment/diagnosis |
US5879303A (en) | 1996-09-27 | 1999-03-09 | Atl Ultrasound | Ultrasonic diagnostic imaging of response frequency differing from transmit frequency |
US5957941A (en) | 1996-09-27 | 1999-09-28 | Boston Scientific Corporation | Catheter system and drive assembly thereof |
US5665053A (en) | 1996-09-27 | 1997-09-09 | Jacobs; Robert A. | Apparatus for performing endermology with ultrasound |
US6283919B1 (en) | 1996-11-26 | 2001-09-04 | Atl Ultrasound | Ultrasonic diagnostic imaging with blended tissue harmonic signals |
US5746005A (en) | 1996-10-22 | 1998-05-05 | Powerhorse Corporation | Angular position sensor |
US6719755B2 (en) | 1996-10-22 | 2004-04-13 | Epicor Medical, Inc. | Methods and devices for ablation |
US5769790A (en) | 1996-10-25 | 1998-06-23 | General Electric Company | Focused ultrasound surgery system guided by ultrasound imaging |
DE69732511T2 (en) | 1996-10-29 | 2006-01-12 | Koninklijke Philips Electronics N.V. | Processing method for signals of objects with moving parts and echography apparatus therefor |
US5827204A (en) | 1996-11-26 | 1998-10-27 | Grandia; Willem | Medical noninvasive operations using focused modulated high power ultrasound |
US5810008A (en) | 1996-12-03 | 1998-09-22 | Isg Technologies Inc. | Apparatus and method for visualizing ultrasonic images |
FR2756741B1 (en) | 1996-12-05 | 1999-01-08 | Cird Galderma | USE OF A CHROMOPHORE IN A COMPOSITION INTENDED TO BE APPLIED TO THE SKIN BEFORE LASER TREATMENT |
US5820564A (en) | 1996-12-16 | 1998-10-13 | Albatross Technologies, Inc. | Method and apparatus for surface ultrasound imaging |
IL120079A (en) | 1997-01-27 | 2001-03-19 | Technion Res & Dev Foundation | Ultrasound system and cosmetic methods utilizing same |
US7789841B2 (en) | 1997-02-06 | 2010-09-07 | Exogen, Inc. | Method and apparatus for connective tissue treatment |
US7108663B2 (en) | 1997-02-06 | 2006-09-19 | Exogen, Inc. | Method and apparatus for cartilage growth stimulation |
US5904659A (en) | 1997-02-14 | 1999-05-18 | Exogen, Inc. | Ultrasonic treatment for wounds |
JPH10248850A (en) | 1997-03-11 | 1998-09-22 | Olympus Optical Co Ltd | Ultrasonic probe |
US5853367A (en) | 1997-03-17 | 1998-12-29 | General Electric Company | Task-interface and communications system and method for ultrasound imager control |
JP4322322B2 (en) | 1997-03-31 | 2009-08-26 | 株式会社東芝 | Ultrasonic therapy device |
US5938612A (en) | 1997-05-05 | 1999-08-17 | Creare Inc. | Multilayer ultrasonic transducer array including very thin layer of transducer elements |
US5840032A (en) | 1997-05-07 | 1998-11-24 | General Electric Company | Method and apparatus for three-dimensional ultrasound imaging using transducer array having uniform elevation beamwidth |
CN1154462C (en) | 1997-05-15 | 2004-06-23 | 松下电工株式会社 | Ultrasonic device |
JP2002505596A (en) | 1997-05-23 | 2002-02-19 | トランサージカル,インコーポレイテッド | MRI guided therapy device and method |
US5931805A (en) | 1997-06-02 | 1999-08-03 | Pharmasonics, Inc. | Catheters comprising bending transducers and methods for their use |
JP3783339B2 (en) | 1997-06-13 | 2006-06-07 | 松下電工株式会社 | Ultrasonic beauty device |
ES2129364B1 (en) | 1997-06-20 | 2000-01-16 | Medicina En Forma S L | A TEAM FOR THE TREATMENT OF CAPSULAR CONTRACTS IN BREAST FACILITIES AND ITS APPLICATION PROCEDURE. |
EP1018955A4 (en) | 1997-06-24 | 2001-06-20 | Laser Aesthetics Inc | Pulsed filament lamp for dermatological treatment |
US5810888A (en) | 1997-06-26 | 1998-09-22 | Massachusetts Institute Of Technology | Thermodynamic adaptive phased array system for activating thermosensitive liposomes in targeted drug delivery |
US5876341A (en) | 1997-06-30 | 1999-03-02 | Siemens Medical Systems, Inc. | Removing beam interleave effect on doppler spectrum in ultrasound imaging |
US20030040442A1 (en) | 1997-07-02 | 2003-02-27 | Nsk Ltd. | Rolling bearing |
US6547788B1 (en) | 1997-07-08 | 2003-04-15 | Atrionx, Inc. | Medical device with sensor cooperating with expandable member |
US6093883A (en) | 1997-07-15 | 2000-07-25 | Focus Surgery, Inc. | Ultrasound intensity determining method and apparatus |
TW370458B (en) | 1997-08-11 | 1999-09-21 | Matsushita Electric Works Ltd | Ultrasonic facial apparatus |
US7981112B1 (en) | 1997-08-12 | 2011-07-19 | Joseph Neev | Home use device and methods for treating skin conditions |
US20020169442A1 (en) | 1997-08-12 | 2002-11-14 | Joseph Neev | Device and a method for treating skin conditions |
ATE326913T1 (en) | 1997-08-13 | 2006-06-15 | Solarant Medical Inc | NON-INVASIVE DEVICES AND SYSTEMS FOR SHRINKING TISSUES |
US6413253B1 (en) | 1997-08-16 | 2002-07-02 | Cooltouch Corporation | Subsurface heating of material |
US6126619A (en) | 1997-09-02 | 2000-10-03 | Transon Llc | Multiple transducer assembly and method for coupling ultrasound energy to a body |
US5990598A (en) | 1997-09-23 | 1999-11-23 | Hewlett-Packard Company | Segment connections for multiple elevation transducers |
US6113558A (en) | 1997-09-29 | 2000-09-05 | Angiosonics Inc. | Pulsed mode lysis method |
US5923099A (en) | 1997-09-30 | 1999-07-13 | Lam Research Corporation | Intelligent backup power controller |
US6049159A (en) | 1997-10-06 | 2000-04-11 | Albatros Technologies, Inc. | Wideband acoustic transducer |
US6500121B1 (en) | 1997-10-14 | 2002-12-31 | Guided Therapy Systems, Inc. | Imaging, therapy, and temperature monitoring ultrasonic system |
US6050943A (en) | 1997-10-14 | 2000-04-18 | Guided Therapy Systems, Inc. | Imaging, therapy, and temperature monitoring ultrasonic system |
JPH11123226A (en) | 1997-10-21 | 1999-05-11 | Prism Rira:Kk | Aesthetic probe using pure titanium |
US6325758B1 (en) | 1997-10-27 | 2001-12-04 | Nomos Corporation | Method and apparatus for target position verification |
US6071239A (en) | 1997-10-27 | 2000-06-06 | Cribbs; Robert W. | Method and apparatus for lipolytic therapy using ultrasound energy |
US20060184071A1 (en) | 1997-12-29 | 2006-08-17 | Julia Therapeutics, Llc | Treatment of skin with acoustic energy |
US20020040199A1 (en) | 1997-12-29 | 2002-04-04 | Klopotek Peter J. | Method and apparatus for therapeutic treatment of skin |
US6325769B1 (en) * | 1998-12-29 | 2001-12-04 | Collapeutics, Llc | Method and apparatus for therapeutic treatment of skin |
US20080027328A1 (en) | 1997-12-29 | 2008-01-31 | Julia Therapeutics, Llc | Multi-focal treatment of skin with acoustic energy |
US6113559A (en) | 1997-12-29 | 2000-09-05 | Klopotek; Peter J. | Method and apparatus for therapeutic treatment of skin with ultrasound |
US6575956B1 (en) | 1997-12-31 | 2003-06-10 | Pharmasonics, Inc. | Methods and apparatus for uniform transcutaneous therapeutic ultrasound |
US6171244B1 (en) | 1997-12-31 | 2001-01-09 | Acuson Corporation | Ultrasonic system and method for storing data |
JPH11244386A (en) | 1998-01-01 | 1999-09-14 | Ge Yokogawa Medical Systems Ltd | Method for stopping blood circulation and heater |
DE19800416C2 (en) | 1998-01-08 | 2002-09-19 | Storz Karl Gmbh & Co Kg | Device for the treatment of body tissue, in particular soft tissue close to the surface, by means of ultrasound |
CN1058905C (en) | 1998-01-25 | 2000-11-29 | 重庆海扶(Hifu)技术有限公司 | High-intensity focus supersonic tumor scanning therapy system |
AU9762998A (en) | 1998-02-05 | 1999-08-23 | Miwa Science Laboratory Inc. | Ultrasonic wave irradiation apparatus |
IL132226A0 (en) | 1998-02-10 | 2001-03-19 | Biosense Inc | Improved catheter calibration |
US20020055702A1 (en) | 1998-02-10 | 2002-05-09 | Anthony Atala | Ultrasound-mediated drug delivery |
US6101407A (en) | 1998-02-13 | 2000-08-08 | Eastman Kodak Company | Method and system for remotely viewing and configuring output from a medical imaging device |
US6325798B1 (en) | 1998-02-19 | 2001-12-04 | Curon Medical, Inc. | Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions |
US6039689A (en) | 1998-03-11 | 2000-03-21 | Riverside Research Institute | Stripe electrode transducer for use with therapeutic ultrasonic radiation treatment |
US6013032A (en) | 1998-03-13 | 2000-01-11 | Hewlett-Packard Company | Beamforming methods and apparatus for three-dimensional ultrasound imaging using two-dimensional transducer array |
US6605080B1 (en) | 1998-03-27 | 2003-08-12 | The General Hospital Corporation | Method and apparatus for the selective targeting of lipid-rich tissues |
US6685640B1 (en) | 1998-03-30 | 2004-02-03 | Focus Surgery, Inc. | Ablation system |
WO1999049788A1 (en) | 1998-03-30 | 1999-10-07 | Focus Surgery, Inc. | Ablation system |
US6432057B1 (en) | 1998-03-31 | 2002-08-13 | Lunar Corporation | Stabilizing acoustic coupler for limb densitometry |
US6030374A (en) | 1998-05-29 | 2000-02-29 | Mcdaniel; David H. | Ultrasound enhancement of percutaneous drug absorption |
US6039048A (en) | 1998-04-08 | 2000-03-21 | Silberg; Barry | External ultrasound treatment of connective tissue |
US6022327A (en) | 1998-05-04 | 2000-02-08 | Chang; Henry Ping | Facial steamer machine with detachable function units |
US6004262A (en) | 1998-05-04 | 1999-12-21 | Ad-Tech Medical Instrument Corp. | Visually-positioned electrical monitoring apparatus |
US5977538A (en) | 1998-05-11 | 1999-11-02 | Imarx Pharmaceutical Corp. | Optoacoustic imaging system |
US6186951B1 (en) | 1998-05-26 | 2001-02-13 | Riverside Research Institute | Ultrasonic systems and methods for fluid perfusion and flow rate measurement |
US6440121B1 (en) | 1998-05-28 | 2002-08-27 | Pearl Technology Holdings, Llc. | Surgical device for performing face-lifting surgery using radiofrequency energy |
US6432101B1 (en) | 1998-05-28 | 2002-08-13 | Pearl Technology Holdings, Llc | Surgical device for performing face-lifting using electromagnetic radiation |
US7494488B2 (en) | 1998-05-28 | 2009-02-24 | Pearl Technology Holdings, Llc | Facial tissue strengthening and tightening device and methods |
US6077294A (en) | 1998-06-11 | 2000-06-20 | Cynosure, Inc. | Method for non-invasive wrinkle removal and skin treatment |
US6425865B1 (en) | 1998-06-12 | 2002-07-30 | The University Of British Columbia | Robotically assisted medical ultrasound |
US6322532B1 (en) | 1998-06-24 | 2001-11-27 | 3M Innovative Properties Company | Sonophoresis method and apparatus |
US6036646A (en) | 1998-07-10 | 2000-03-14 | Guided Therapy Systems, Inc. | Method and apparatus for three dimensional ultrasound imaging |
US6889089B2 (en) | 1998-07-28 | 2005-05-03 | Scimed Life Systems, Inc. | Apparatus and method for treating tumors near the surface of an organ |
WO2000006032A1 (en) | 1998-07-29 | 2000-02-10 | Pharmasonics, Inc. | Ultrasonic enhancement of drug injection |
US20030009153A1 (en) | 1998-07-29 | 2003-01-09 | Pharmasonics, Inc. | Ultrasonic enhancement of drug injection |
US6443914B1 (en) | 1998-08-10 | 2002-09-03 | Lysonix, Inc. | Apparatus and method for preventing and treating cellulite |
US6042556A (en) | 1998-09-04 | 2000-03-28 | University Of Washington | Method for determining phase advancement of transducer elements in high intensity focused ultrasound |
CA2343361A1 (en) | 1998-09-11 | 2000-03-23 | Berkshire Laboratories, Inc. | Methods for using resonant acoustic energy to detect or effect structures |
IL126236A0 (en) | 1998-09-16 | 1999-05-09 | Ultra Cure Ltd | A method device and system for skin peeling |
US6425867B1 (en) | 1998-09-18 | 2002-07-30 | University Of Washington | Noise-free real time ultrasonic imaging of a treatment site undergoing high intensity focused ultrasound therapy |
US7686763B2 (en) | 1998-09-18 | 2010-03-30 | University Of Washington | Use of contrast agents to increase the effectiveness of high intensity focused ultrasound therapy |
JP3330092B2 (en) | 1998-09-30 | 2002-09-30 | 松下電器産業株式会社 | Ultrasound diagnostic equipment |
JP4460691B2 (en) | 1998-09-30 | 2010-05-12 | 株式会社東芝 | Ultrasonic therapy device |
IL126505A0 (en) | 1998-10-09 | 1999-08-17 | Ultra Cure Ltd | A method and device for hair removal |
US6302848B1 (en) | 1999-07-01 | 2001-10-16 | Sonotech, Inc. | In vivo biocompatible acoustic coupling media |
US6540700B1 (en) | 1998-10-26 | 2003-04-01 | Kabushiki Kaisha Toshiba | Ultrasound treatment apparatus |
JP2000126310A (en) | 1998-10-26 | 2000-05-09 | Ya Man Ltd | Ultrasonic friction cosmetic therapy device |
JP4095729B2 (en) | 1998-10-26 | 2008-06-04 | 株式会社日立製作所 | Therapeutic ultrasound system |
EP1125121B1 (en) | 1998-10-28 | 2007-12-12 | Covaris, Inc. | Apparatus and methods for controlling sonic treatment |
US6948843B2 (en) | 1998-10-28 | 2005-09-27 | Covaris, Inc. | Method and apparatus for acoustically controlling liquid solutions in microfluidic devices |
US6080108A (en) | 1998-11-17 | 2000-06-27 | Atl Ultrasound, Inc. | Scanning aid for quantified three dimensional ultrasonic diagnostic imaging |
US6645145B1 (en) | 1998-11-19 | 2003-11-11 | Siemens Medical Solutions Usa, Inc. | Diagnostic medical ultrasound systems and transducers utilizing micro-mechanical components |
US6605043B1 (en) | 1998-11-19 | 2003-08-12 | Acuson Corp. | Diagnostic medical ultrasound systems and transducers utilizing micro-mechanical components |
US6159150A (en) | 1998-11-20 | 2000-12-12 | Acuson Corporation | Medical diagnostic ultrasonic imaging system with auxiliary processor |
US6142946A (en) | 1998-11-20 | 2000-11-07 | Atl Ultrasound, Inc. | Ultrasonic diagnostic imaging system with cordless scanheads |
AU1128600A (en) | 1998-11-20 | 2000-06-13 | Joie P. Jones | Methods for selectively dissolving and removing materials using ultra-high frequency ultrasound |
US6676655B2 (en) | 1998-11-30 | 2004-01-13 | Light Bioscience L.L.C. | Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen |
US6887260B1 (en) | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
US6936044B2 (en) | 1998-11-30 | 2005-08-30 | Light Bioscience, Llc | Method and apparatus for the stimulation of hair growth |
JP4089058B2 (en) | 1998-12-10 | 2008-05-21 | ソニー株式会社 | Cleaning device and cleaning method for printing screen |
US6309355B1 (en) | 1998-12-22 | 2001-10-30 | The Regents Of The University Of Michigan | Method and assembly for performing ultrasound surgery using cavitation |
US6296619B1 (en) | 1998-12-30 | 2001-10-02 | Pharmasonics, Inc. | Therapeutic ultrasonic catheter for delivering a uniform energy dose |
US6428532B1 (en) | 1998-12-30 | 2002-08-06 | The General Hospital Corporation | Selective tissue targeting by difference frequency of two wavelengths |
US6183773B1 (en) | 1999-01-04 | 2001-02-06 | The General Hospital Corporation | Targeting of sebaceous follicles as a treatment of sebaceous gland disorders |
JP2000214966A (en) | 1999-01-20 | 2000-08-04 | Ricoh Co Ltd | Portable information processor |
US6200308B1 (en) | 1999-01-29 | 2001-03-13 | Candela Corporation | Dynamic cooling of tissue for radiation treatment |
JP2000233009A (en) | 1999-02-16 | 2000-08-29 | Ya Man Ltd | Temperature-controlled probe of ultrasonic cosmetic unit |
US6139499A (en) | 1999-02-22 | 2000-10-31 | Wilk; Peter J. | Ultrasonic medical system and associated method |
KR20000059516A (en) | 1999-03-04 | 2000-10-05 | 임영환 | Method of transmitting and executing multimedia presentation mail and apparatus thereby |
US6508774B1 (en) | 1999-03-09 | 2003-01-21 | Transurgical, Inc. | Hifu applications with feedback control |
EP1158919B1 (en) | 1999-03-09 | 2005-06-29 | Thermage, Inc. | Apparatus for treatment of tissue |
US6775404B1 (en) | 1999-03-18 | 2004-08-10 | University Of Washington | Apparatus and method for interactive 3D registration of ultrasound and magnetic resonance images based on a magnetic position sensor |
US6375672B1 (en) | 1999-03-22 | 2002-04-23 | Board Of Trustees Of Michigan State University | Method for controlling the chemical and heat induced responses of collagenous materials |
US6461304B1 (en) | 1999-03-30 | 2002-10-08 | Fuji Photo Optical Co., Ltd. | Ultrasound inspection apparatus detachably connected to endoscope |
US6488626B1 (en) | 1999-04-07 | 2002-12-03 | Riverside Research Institute | Ultrasonic sensing by induced tissue motion |
US6408212B1 (en) | 1999-04-13 | 2002-06-18 | Joseph Neev | Method for treating acne |
US6210327B1 (en) | 1999-04-28 | 2001-04-03 | General Electric Company | Method and apparatus for sending ultrasound image data to remotely located device |
US6268405B1 (en) | 1999-05-04 | 2001-07-31 | Porex Surgical, Inc. | Hydrogels and methods of making and using same |
US6251088B1 (en) | 1999-05-12 | 2001-06-26 | Jonathan J. Kaufman | Ultrasonic plantar fasciitis therapy: apparatus and method |
US6666835B2 (en) | 1999-05-14 | 2003-12-23 | University Of Washington | Self-cooled ultrasonic applicator for medical applications |
US20030060736A1 (en) | 1999-05-14 | 2003-03-27 | Martin Roy W. | Lens-focused ultrasonic applicator for medical applications |
US6217530B1 (en) | 1999-05-14 | 2001-04-17 | University Of Washington | Ultrasonic applicator for medical applications |
US6233476B1 (en) | 1999-05-18 | 2001-05-15 | Mediguide Ltd. | Medical positioning system |
US7399279B2 (en) | 1999-05-28 | 2008-07-15 | Physiosonics, Inc | Transmitter patterns for multi beam reception |
US20040015079A1 (en) | 1999-06-22 | 2004-01-22 | Teratech Corporation | Ultrasound probe with integrated electronics |
US6193658B1 (en) | 1999-06-24 | 2001-02-27 | Martin E Wendelken | Method and kit for wound evaluation |
US6287257B1 (en) | 1999-06-29 | 2001-09-11 | Acuson Corporation | Method and system for configuring a medical diagnostic ultrasound imaging system |
CA2471783A1 (en) | 1999-06-30 | 2003-07-03 | Edward W. Knowlton | Liquid cooled rf handpiece |
GB9915707D0 (en) | 1999-07-05 | 1999-09-08 | Young Michael J R | Method and apparatus for focused treatment of subcutaneous blood vessels |
US20030216795A1 (en) | 1999-07-07 | 2003-11-20 | Yoram Harth | Apparatus and method for high energy photodynamic therapy of acne vulgaris, seborrhea and other skin disorders |
EP1207788A4 (en) | 1999-07-19 | 2009-12-09 | St Jude Medical Atrial Fibrill | Apparatus and method for ablating tissue |
US6390982B1 (en) | 1999-07-23 | 2002-05-21 | Univ Florida | Ultrasonic guidance of target structures for medical procedures |
US6307302B1 (en) | 1999-07-23 | 2001-10-23 | Measurement Specialities, Inc. | Ultrasonic transducer having impedance matching layer |
US6451007B1 (en) | 1999-07-29 | 2002-09-17 | Dale E. Koop | Thermal quenching of tissue |
US6533726B1 (en) | 1999-08-09 | 2003-03-18 | Riverside Research Institute | System and method for ultrasonic harmonic imaging for therapy guidance and monitoring |
US20020173721A1 (en) | 1999-08-20 | 2002-11-21 | Novasonics, Inc. | User interface for handheld imaging devices |
AU7362400A (en) | 1999-09-10 | 2001-04-10 | Transurgical, Inc. | Occlusion of tubular anatomical structures by energy application |
US7510536B2 (en) | 1999-09-17 | 2009-03-31 | University Of Washington | Ultrasound guided high intensity focused ultrasound treatment of nerves |
US6123081A (en) | 1999-09-22 | 2000-09-26 | Durette; Jean-Francois | Ocular surgical protective shield |
US6301989B1 (en) | 1999-09-30 | 2001-10-16 | Civco Medical Instruments, Inc. | Medical imaging instrument positioning device |
US6198956B1 (en) | 1999-09-30 | 2001-03-06 | Oti Ophthalmic Technologies Inc. | High speed sector scanning apparatus having digital electronic control |
US20040158150A1 (en) | 1999-10-05 | 2004-08-12 | Omnisonics Medical Technologies, Inc. | Apparatus and method for an ultrasonic medical device for tissue remodeling |
US6287304B1 (en) | 1999-10-15 | 2001-09-11 | Neothermia Corporation | Interstitial cauterization of tissue volumes with electrosurgically deployed electrodes |
US6440071B1 (en) | 1999-10-18 | 2002-08-27 | Guided Therapy Systems, Inc. | Peripheral ultrasound imaging system |
WO2001028623A2 (en) | 1999-10-18 | 2001-04-26 | Focus Surgery, Inc. | Split beam transducer |
US6656136B1 (en) | 1999-10-25 | 2003-12-02 | Therus Corporation | Use of focused ultrasound for vascular sealing |
US20050240170A1 (en) | 1999-10-25 | 2005-10-27 | Therus Corporation | Insertable ultrasound probes, systems, and methods for thermal therapy |
US20030229331A1 (en) | 1999-11-05 | 2003-12-11 | Pharmasonics, Inc. | Methods and apparatus for uniform transcutaneous therapeutic ultrasound |
US6338716B1 (en) | 1999-11-24 | 2002-01-15 | Acuson Corporation | Medical diagnostic ultrasonic transducer probe and imaging system for use with a position and orientation sensor |
US6626855B1 (en) | 1999-11-26 | 2003-09-30 | Therus Corpoation | Controlled high efficiency lesion formation using high intensity ultrasound |
US6325540B1 (en) | 1999-11-29 | 2001-12-04 | General Electric Company | Method and apparatus for remotely configuring and servicing a field replaceable unit in a medical diagnostic system |
US6356780B1 (en) | 1999-12-22 | 2002-03-12 | General Electric Company | Method and apparatus for managing peripheral devices in a medical imaging system |
JP2004512856A (en) | 1999-12-23 | 2004-04-30 | シーラス、コーポレイション | Imaging and therapeutic ultrasound transducers |
US6436061B1 (en) | 1999-12-29 | 2002-08-20 | Peter D. Costantino | Ultrasound treatment of varicose veins |
US6699237B2 (en) | 1999-12-30 | 2004-03-02 | Pearl Technology Holdings, Llc | Tissue-lifting device |
US6451013B1 (en) | 2000-01-19 | 2002-09-17 | Medtronic Xomed, Inc. | Methods of tonsil reduction using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
US6595934B1 (en) | 2000-01-19 | 2003-07-22 | Medtronic Xomed, Inc. | Methods of skin rejuvenation using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
US7338434B1 (en) | 2002-08-21 | 2008-03-04 | Medtronic, Inc. | Method and system for organ positioning and stabilization |
US6447443B1 (en) | 2001-01-13 | 2002-09-10 | Medtronic, Inc. | Method for organ positioning and stabilization |
US7706882B2 (en) | 2000-01-19 | 2010-04-27 | Medtronic, Inc. | Methods of using high intensity focused ultrasound to form an ablated tissue area |
US6692450B1 (en) | 2000-01-19 | 2004-02-17 | Medtronic Xomed, Inc. | Focused ultrasound ablation devices having selectively actuatable ultrasound emitting elements and methods of using the same |
US6409720B1 (en) | 2000-01-19 | 2002-06-25 | Medtronic Xomed, Inc. | Methods of tongue reduction using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
US6361531B1 (en) | 2000-01-21 | 2002-03-26 | Medtronic Xomed, Inc. | Focused ultrasound ablation devices having malleable handle shafts and methods of using the same |
US6517484B1 (en) | 2000-02-28 | 2003-02-11 | Wilk Patent Development Corporation | Ultrasonic imaging system and associated method |
US6511427B1 (en) | 2000-03-10 | 2003-01-28 | Acuson Corporation | System and method for assessing body-tissue properties using a medical ultrasound transducer probe with a body-tissue parameter measurement mechanism |
US6428477B1 (en) | 2000-03-10 | 2002-08-06 | Koninklijke Philips Electronics, N.V. | Delivery of theraputic ultrasound by two dimensional ultrasound array |
US6613004B1 (en) | 2000-04-21 | 2003-09-02 | Insightec-Txsonics, Ltd. | Systems and methods for creating longer necrosed volumes using a phased array focused ultrasound system |
US6419648B1 (en) | 2000-04-21 | 2002-07-16 | Insightec-Txsonics Ltd. | Systems and methods for reducing secondary hot spots in a phased array focused ultrasound system |
AU2001257328A1 (en) | 2000-04-28 | 2001-11-12 | Focus Surgery, Inc. | Ablation system with visualization |
AU2001255724A1 (en) | 2000-04-29 | 2001-11-12 | Focus Surgery, Inc. | Non-invasive tissue characterization |
US6312385B1 (en) | 2000-05-01 | 2001-11-06 | Ge Medical Systems Global Technology Company, Llc | Method and apparatus for automatic detection and sizing of cystic objects |
WO2001089723A1 (en) | 2000-05-22 | 2001-11-29 | Miwa Science Laboratory Inc. | Ultrasonic irradiation apparatus |
WO2002003873A2 (en) | 2000-07-10 | 2002-01-17 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH | Radiofrequency probes for tissue treatment and methods of use |
US6506171B1 (en) | 2000-07-27 | 2003-01-14 | Insightec-Txsonics, Ltd | System and methods for controlling distribution of acoustic energy around a focal point using a focused ultrasound system |
US6582381B1 (en) | 2000-07-31 | 2003-06-24 | Txsonics Ltd. | Mechanical positioner for MRI guided ultrasound therapy system |
AU2000264703A1 (en) | 2000-07-31 | 2002-02-13 | El. En. S.P.A. | Method and device for epilation by ultrasound |
JP3556582B2 (en) | 2000-08-02 | 2004-08-18 | 松下電器産業株式会社 | Ultrasound diagnostic equipment |
ATE463237T1 (en) | 2000-08-16 | 2010-04-15 | Gen Hospital Corp | TOPICAL AMINOLEVULIC ACID PHOTODYNAMIC THERAPY FOR ACNE VULGARIS |
US20040073115A1 (en) | 2000-08-24 | 2004-04-15 | Timi 3 Systems, Inc. | Systems and methods for applying ultrasound energy to increase tissue perfusion and/or vasodilation without substantial deep heating of tissue |
WO2002015768A2 (en) | 2000-08-24 | 2002-02-28 | Timi 3 Systems, Inc. | Systems and method for applying ultrasonic energy |
US20020072691A1 (en) | 2000-08-24 | 2002-06-13 | Timi 3 Systems, Inc. | Systems and methods for applying ultrasonic energy to the thoracic cavity |
US7335169B2 (en) | 2000-08-24 | 2008-02-26 | Timi 3 Systems, Inc. | Systems and methods for delivering ultrasound energy at an output power level that remains essentially constant despite variations in transducer impedance |
US6790187B2 (en) | 2000-08-24 | 2004-09-14 | Timi 3 Systems, Inc. | Systems and methods for applying ultrasonic energy |
US20020082529A1 (en) | 2000-08-24 | 2002-06-27 | Timi 3 Systems, Inc. | Systems and methods for applying pulsed ultrasonic energy |
JP2002078764A (en) | 2000-09-06 | 2002-03-19 | Purotec Fuji:Kk | Portable cosmetic massage machine |
WO2002024050A2 (en) | 2000-09-19 | 2002-03-28 | Focus Surgery, Inc. | Tissue treatment method and apparatus |
US6524250B1 (en) | 2000-09-19 | 2003-02-25 | Pearl Technology Holdings, Llc | Fat layer thickness mapping system to guide liposuction surgery |
US6910139B2 (en) | 2000-10-02 | 2005-06-21 | Fujitsu Limited | Software processing apparatus with a switching processing unit for displaying animation images in an environment operating base on type of power supply |
KR100400870B1 (en) | 2000-10-10 | 2003-10-08 | 김영애 | remote dermal diagnosing and curing device |
US6882884B1 (en) | 2000-10-13 | 2005-04-19 | Soundskin, L.L.C. | Process for the stimulation of production of extracellular dermal proteins in human tissue |
JP2001170068A (en) | 2000-10-16 | 2001-06-26 | Toshiba Corp | Ultrasonic treatment instrument |
US7778685B2 (en) | 2000-10-18 | 2010-08-17 | Paieon Inc. | Method and system for positioning a device in a tubular organ |
US6540685B1 (en) | 2000-11-09 | 2003-04-01 | Koninklijke Philips Electronics N.V. | Ultrasound diagnostic device |
US6821274B2 (en) | 2001-03-07 | 2004-11-23 | Gendel Ltd. | Ultrasound therapy for selective cell ablation |
US6618620B1 (en) | 2000-11-28 | 2003-09-09 | Txsonics Ltd. | Apparatus for controlling thermal dosing in an thermal treatment system |
AU2002239360A1 (en) | 2000-11-28 | 2002-06-11 | Allez Physionix Limited | Systems and methods for making non-invasive physiological assessments |
GB0030449D0 (en) | 2000-12-13 | 2001-01-24 | Deltex Guernsey Ltd | Improvements in or relating to doppler haemodynamic monitors |
US6746444B2 (en) | 2000-12-18 | 2004-06-08 | Douglas J. Key | Method of amplifying a beneficial selective skin response to light energy |
US6761729B2 (en) | 2000-12-22 | 2004-07-13 | Advanced Medicalapplications, Inc. | Wound treatment method and device with combination of ultrasound and laser energy |
US6626854B2 (en) | 2000-12-27 | 2003-09-30 | Insightec - Txsonics Ltd. | Systems and methods for ultrasound assisted lipolysis |
US6645162B2 (en) | 2000-12-27 | 2003-11-11 | Insightec - Txsonics Ltd. | Systems and methods for ultrasound assisted lipolysis |
CN101194856A (en) | 2000-12-28 | 2008-06-11 | 帕洛玛医疗技术有限公司 | Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor |
US7914453B2 (en) | 2000-12-28 | 2011-03-29 | Ardent Sound, Inc. | Visual imaging system for ultrasonic probe |
US20080183162A1 (en) | 2000-12-28 | 2008-07-31 | Palomar Medical Technologies, Inc. | Methods And Devices For Fractional Ablation Of Tissue |
BR0116707A (en) | 2001-01-03 | 2005-08-16 | Ultrashape Inc | Non-evasive ultrasonic body contour |
US7347855B2 (en) | 2001-10-29 | 2008-03-25 | Ultrashape Ltd. | Non-invasive ultrasonic body contouring |
US6607498B2 (en) | 2001-01-03 | 2003-08-19 | Uitra Shape, Inc. | Method and apparatus for non-invasive body contouring by lysing adipose tissue |
US6645150B2 (en) | 2001-01-05 | 2003-11-11 | Bjorn A. J. Angelsen | Wide or multiple frequency band ultrasound transducer and transducer arrays |
US6569099B1 (en) | 2001-01-12 | 2003-05-27 | Eilaz Babaev | Ultrasonic method and device for wound treatment |
JP2002209905A (en) | 2001-01-22 | 2002-07-30 | Hitachi Medical Corp | Ultrasonic therapy probe and ultrasonic therapy apparatus |
US6626834B2 (en) | 2001-01-25 | 2003-09-30 | Shane Dunne | Spiral scanner with electronic control |
US6740040B1 (en) | 2001-01-30 | 2004-05-25 | Advanced Cardiovascular Systems, Inc. | Ultrasound energy driven intraventricular catheter to treat ischemia |
JP2002238919A (en) | 2001-02-20 | 2002-08-27 | Olympus Optical Co Ltd | Control apparatus for medical care system and medical care system |
JP2002248153A (en) | 2001-02-23 | 2002-09-03 | Matsushita Electric Works Ltd | Ultrasonic cosmetic device |
US6569108B2 (en) | 2001-03-28 | 2003-05-27 | Profile, Llc | Real time mechanical imaging of the prostate |
US6804327B2 (en) | 2001-04-03 | 2004-10-12 | Lambda Physik Ag | Method and apparatus for generating high output power gas discharge based source of extreme ultraviolet radiation and/or soft x-rays |
US20020165529A1 (en) | 2001-04-05 | 2002-11-07 | Danek Christopher James | Method and apparatus for non-invasive energy delivery |
US6478754B1 (en) | 2001-04-23 | 2002-11-12 | Advanced Medical Applications, Inc. | Ultrasonic method and device for wound treatment |
US6663627B2 (en) | 2001-04-26 | 2003-12-16 | Medtronic, Inc. | Ablation system and method of use |
WO2002087692A1 (en) | 2001-04-26 | 2002-11-07 | The Procter & Gamble Company | A method and apparatus for the treatment of cosmetic skin conditioins |
GB0111440D0 (en) | 2001-05-10 | 2001-07-04 | Procter & Gamble | Method and kit for the treatment or prevention of cosmetic skin conditions |
JP3937755B2 (en) | 2001-05-28 | 2007-06-27 | 松下電工株式会社 | Ultrasonic beauty device |
US7846096B2 (en) | 2001-05-29 | 2010-12-07 | Ethicon Endo-Surgery, Inc. | Method for monitoring of medical treatment using pulse-echo ultrasound |
US20030092988A1 (en) | 2001-05-29 | 2003-05-15 | Makin Inder Raj S. | Staging medical treatment using ultrasound |
US7058440B2 (en) | 2001-06-28 | 2006-06-06 | Koninklijke Philips Electronics N.V. | Dynamic computed tomography imaging using positional state modeling |
US6659956B2 (en) | 2001-06-29 | 2003-12-09 | Barzell-Whitmore Maroon Bells, Inc. | Medical instrument positioner |
US7056331B2 (en) | 2001-06-29 | 2006-06-06 | Quill Medical, Inc. | Suture method |
US6932771B2 (en) | 2001-07-09 | 2005-08-23 | Civco Medical Instruments Co., Inc. | Tissue warming device and method |
JP5041636B2 (en) | 2001-07-12 | 2012-10-03 | 株式会社Adeka | Antimicrobial composition for medical devices |
FR2827149B1 (en) | 2001-07-13 | 2003-10-10 | Technomed Medical Systems | FOCUSED ULTRASOUND TREATMENT PROBE |
JP2003050298A (en) | 2001-08-06 | 2003-02-21 | Fuji Photo Film Co Ltd | Radiographic image conversion panel and its manufacturing method |
US7018396B2 (en) | 2001-08-07 | 2006-03-28 | New England Medical Center Hospitals, Inc. | Method of treating acne |
US20030032900A1 (en) | 2001-08-08 | 2003-02-13 | Engii (2001) Ltd. | System and method for facial treatment |
DE10140064A1 (en) | 2001-08-16 | 2003-03-13 | Rainer Weismueller | Cosmetic or medical treatment of the skin using ultrasound waves, e.g. permanent hair removal using a simple device comprising a mechanical oscillator and focussing lenses with a spacer for varying the distance to the skin |
US7094252B2 (en) | 2001-08-21 | 2006-08-22 | Cooltouch Incorporated | Enhanced noninvasive collagen remodeling |
US6537220B1 (en) | 2001-08-31 | 2003-03-25 | Siemens Medical Solutions Usa, Inc. | Ultrasound imaging with acquisition of imaging data in perpendicular scan planes |
US6773409B2 (en) | 2001-09-19 | 2004-08-10 | Surgrx Llc | Surgical system for applying ultrasonic energy to tissue |
US6638226B2 (en) | 2001-09-28 | 2003-10-28 | Teratech Corporation | Ultrasound imaging system |
US6974417B2 (en) | 2001-10-05 | 2005-12-13 | Queen's University At Kingston | Ultrasound transducer array |
US6659223B2 (en) | 2001-10-05 | 2003-12-09 | Collins & Aikman Products Co. | Sound attenuating material for use within vehicles and methods of making same |
US6709397B2 (en) | 2001-10-16 | 2004-03-23 | Envisioneering, L.L.C. | Scanning probe |
US6920883B2 (en) | 2001-11-08 | 2005-07-26 | Arthrocare Corporation | Methods and apparatus for skin treatment |
US7115093B2 (en) | 2001-11-21 | 2006-10-03 | Ge Medical Systems Global Technology Company, Llc | Method and system for PDA-based ultrasound system |
US7317818B2 (en) | 2001-11-26 | 2008-01-08 | L'ORéAL S.A. | Method of enabling an analysis of an external body portion |
US7601120B2 (en) | 2001-11-30 | 2009-10-13 | Petro Moilanen | Method and device for the non-invasive assessment of bones |
US6554771B1 (en) | 2001-12-18 | 2003-04-29 | Koninklijke Philips Electronics N.V. | Position sensor in ultrasound transducer probe |
US6746402B2 (en) | 2002-01-02 | 2004-06-08 | E. Tuncay Ustuner | Ultrasound system and method |
JP2003204982A (en) | 2002-01-09 | 2003-07-22 | Byeong Gon Kim | Abdomen warming and vibrating belt |
SE520857C2 (en) | 2002-01-15 | 2003-09-02 | Ultrazonix Dnt Ab | Device with both therapeutic and diagnostic sensors for mini-invasive ultrasound treatment of an object, where the therapeutic sensor is thermally insulated |
AU2003209287A1 (en) | 2002-01-15 | 2003-07-30 | The Regents Of The University Of California | System and method providing directional ultrasound therapy to skeletal joints |
TWI220386B (en) | 2002-01-21 | 2004-08-21 | Matsushita Electric Works Ltd | Ultrasonic transdermal permeation device |
US7819826B2 (en) | 2002-01-23 | 2010-10-26 | The Regents Of The University Of California | Implantable thermal treatment method and apparatus |
JP4363987B2 (en) | 2002-01-29 | 2009-11-11 | ヤング、マイケル・ジョン・ラドリー | Device for converging ultrasonic vibration beams |
US6755789B2 (en) | 2002-02-05 | 2004-06-29 | Inceptio Medical Technologies, Llc | Ultrasonic vascular imaging system and method of blood vessel cannulation |
JP2005517183A (en) | 2002-02-07 | 2005-06-09 | ベーリンガー インゲルハイム (カナダ) リミテッド | E2 displacement assay to identify inhibitors of HPV |
JP4265139B2 (en) | 2002-02-18 | 2009-05-20 | コニカミノルタホールディングス株式会社 | Radiation image conversion panel and radiation image reading apparatus |
WO2003070105A1 (en) | 2002-02-20 | 2003-08-28 | Liposonix, Inc. | Ultrasonic treatment and imaging of adipose tissue |
JP2003248097A (en) | 2002-02-25 | 2003-09-05 | Konica Corp | Radiation image conversion panel and its production method |
US6648839B2 (en) | 2002-02-28 | 2003-11-18 | Misonix, Incorporated | Ultrasonic medical treatment device for RF cauterization and related method |
US20030171701A1 (en) | 2002-03-06 | 2003-09-11 | Eilaz Babaev | Ultrasonic method and device for lypolytic therapy |
US6824516B2 (en) | 2002-03-11 | 2004-11-30 | Medsci Technologies, Inc. | System for examining, mapping, diagnosing, and treating diseases of the prostate |
US8840608B2 (en) | 2002-03-15 | 2014-09-23 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
IL148791A0 (en) | 2002-03-20 | 2002-09-12 | Yoni Iger | Method and apparatus for altering activity of tissue layers |
US6662054B2 (en) | 2002-03-26 | 2003-12-09 | Syneron Medical Ltd. | Method and system for treating skin |
US7534211B2 (en) | 2002-03-29 | 2009-05-19 | Sonosite, Inc. | Modular apparatus for diagnostic ultrasound |
JP2003309890A (en) | 2002-04-17 | 2003-10-31 | Matsushita Electric Ind Co Ltd | Ultrasonic probe |
JP2003305050A (en) | 2002-04-17 | 2003-10-28 | Olympus Optical Co Ltd | Ultrasonic operation apparatus |
US6887239B2 (en) | 2002-04-17 | 2005-05-03 | Sontra Medical Inc. | Preparation for transmission and reception of electrical signals |
US7000126B2 (en) | 2002-04-18 | 2006-02-14 | Intel Corporation | Method for media content presentation in consideration of system power |
DE10219297A1 (en) | 2002-04-25 | 2003-11-06 | Laser & Med Tech Gmbh | Medical instrument for generation of scar tissue to stiffen soft tissue, combines an ultrasound generator with a laser so that electromagnetic and or ultrasound energy can be coupled into the tissue via an opto-acoustic coupler |
US20030236487A1 (en) | 2002-04-29 | 2003-12-25 | Knowlton Edward W. | Method for treatment of tissue with feedback |
DE10219217B3 (en) | 2002-04-29 | 2004-02-12 | Creative-Line Gmbh | Object with picture built up from lines, e.g. for decoration, has line pattern eroded into main surface |
US6992305B2 (en) | 2002-05-08 | 2006-01-31 | Konica Corporation | Radiation image converting panel and production method of the same |
US20030212129A1 (en) | 2002-05-13 | 2003-11-13 | Liu Kay Miyakawa | System and method for revitalizing human skin |
US6846290B2 (en) * | 2002-05-14 | 2005-01-25 | Riverside Research Institute | Ultrasound method and system |
US7359745B2 (en) | 2002-05-15 | 2008-04-15 | Case Western Reserve University | Method to correct magnetic field/phase variations in proton resonance frequency shift thermometry in magnetic resonance imaging |
WO2003096883A2 (en) | 2002-05-16 | 2003-11-27 | Barbara Ann Karmanos Cancer Institute | Combined diagnostic and therapeutic ultrasound system |
US7967839B2 (en) | 2002-05-20 | 2011-06-28 | Rocky Mountain Biosystems, Inc. | Electromagnetic treatment of tissues and cells |
US6958043B2 (en) | 2002-05-21 | 2005-10-25 | Medtronic Xomed, Inc. | Apparatus and method for displacing the partition between the middle ear and the inner ear using a manually powered device |
US7179238B2 (en) | 2002-05-21 | 2007-02-20 | Medtronic Xomed, Inc. | Apparatus and methods for directly displacing the partition between the middle ear and inner ear at an infrasonic frequency |
JP2005526579A (en) | 2002-05-23 | 2005-09-08 | ジェンデル・リミテッド | Shochu device |
US20070213698A1 (en) | 2006-03-10 | 2007-09-13 | Palomar Medical Technologies, Inc. | Photocosmetic device |
WO2003101530A2 (en) | 2002-05-30 | 2003-12-11 | University Of Washington | Solid hydrogel coupling for ultrasound imaging and therapy |
US20030233085A1 (en) | 2002-06-18 | 2003-12-18 | Pedro Giammarusti | Optimization of transcutaneous active permeation of compounds through the synergistic use of ultrasonically generated mechanical abrasion of the skin, chemical enhancers and simultaneous application of sonophoresis, iontophoresis, electroporation, mechanical vibrations and magnetophoresis through single application devices |
JP2005535370A (en) | 2002-06-19 | 2005-11-24 | パロマー・メディカル・テクノロジーズ・インコーポレイテッド | Method and apparatus for treating skin and subcutaneous conditions |
AU2002345319B2 (en) | 2002-06-25 | 2008-03-06 | Ultrashape Ltd. | Devices and methodologies useful in body aesthetics |
US20040001809A1 (en) | 2002-06-26 | 2004-01-01 | Pharmasonics, Inc. | Methods and apparatus for enhancing a response to nucleic acid vaccines |
US7022080B2 (en) | 2002-06-27 | 2006-04-04 | Acuson Corporation | Electrical and mechanical enhancements for a modular transducer system |
US20040082859A1 (en) | 2002-07-01 | 2004-04-29 | Alan Schaer | Method and apparatus employing ultrasound energy to treat body sphincters |
US20040049134A1 (en) | 2002-07-02 | 2004-03-11 | Tosaya Carol A. | System and methods for treatment of alzheimer's and other deposition-related disorders of the brain |
KR100872242B1 (en) | 2002-08-29 | 2008-12-05 | 엘지전자 주식회사 | Computor of Portable composition type |
JP3728283B2 (en) | 2002-08-30 | 2005-12-21 | キヤノン株式会社 | Recording device |
JP2004147719A (en) | 2002-10-29 | 2004-05-27 | Toshiba Corp | Ultrasonic wave irradiation apparatus |
US20040122493A1 (en) | 2002-09-09 | 2004-06-24 | Kabushiki Kaisha Toshiba | Ultrasonic irradiation apparatus |
US7234106B2 (en) | 2002-09-10 | 2007-06-19 | Simske Steven J | System for and method of generating image annotation information |
US20070219604A1 (en) | 2006-03-20 | 2007-09-20 | Palomar Medical Technologies, Inc. | Treatment of tissue with radiant energy |
US6669638B1 (en) | 2002-10-10 | 2003-12-30 | Koninklijke Philips Electronics N.V. | Imaging ultrasound transducer temperature control system and method |
US6709392B1 (en) | 2002-10-10 | 2004-03-23 | Koninklijke Philips Electronics N.V. | Imaging ultrasound transducer temperature control system and method using feedback |
US7004940B2 (en) | 2002-10-10 | 2006-02-28 | Ethicon, Inc. | Devices for performing thermal ablation having movable ultrasound transducers |
US6921371B2 (en) | 2002-10-14 | 2005-07-26 | Ekos Corporation | Ultrasound radiating members for catheter |
US6860852B2 (en) | 2002-10-25 | 2005-03-01 | Compex Medical S.A. | Ultrasound therapeutic device |
AU2003278424A1 (en) | 2002-11-06 | 2004-06-07 | Koninklijke Philips Electronics N.V. | Phased array acoustic system for 3d imaging of moving parts_____ |
US7676047B2 (en) | 2002-12-03 | 2010-03-09 | Bose Corporation | Electroacoustical transducing with low frequency augmenting devices |
US8088067B2 (en) | 2002-12-23 | 2012-01-03 | Insightec Ltd. | Tissue aberration corrections in ultrasound therapy |
US20040143297A1 (en) | 2003-01-21 | 2004-07-22 | Maynard Ramsey | Advanced automatic external defibrillator powered by alternative and optionally multiple electrical power sources and a new business method for single use AED distribution and refurbishment |
US7150716B2 (en) | 2003-02-20 | 2006-12-19 | Siemens Medical Solutions Usa, Inc. | Measuring transducer movement methods and systems for multi-dimensional ultrasound imaging |
US20120035473A1 (en) | 2003-03-10 | 2012-02-09 | Focus Surgery, Inc. | Laparoscopic hifu probe |
US20030191396A1 (en) | 2003-03-10 | 2003-10-09 | Sanghvi Narendra T | Tissue treatment method and apparatus |
US7914469B2 (en) | 2003-03-13 | 2011-03-29 | Real Aesthetics Ltd. | Cellulite ultrasound treatment |
US6918907B2 (en) | 2003-03-13 | 2005-07-19 | Boston Scientific Scimed, Inc. | Surface electrode multiple mode operation |
US6733449B1 (en) | 2003-03-20 | 2004-05-11 | Siemens Medical Solutions Usa, Inc. | System and method for real-time streaming of ultrasound data to a diagnostic medical ultrasound streaming application |
JP2004297951A (en) | 2003-03-27 | 2004-10-21 | Olympus Corp | Ultrasonic vibrator and ultrasonic motor |
WO2004089188A2 (en) | 2003-03-31 | 2004-10-21 | Liposonix, Inc. | Vortex transducer |
US20040206365A1 (en) | 2003-03-31 | 2004-10-21 | Knowlton Edward Wells | Method for treatment of tissue |
US9149322B2 (en) | 2003-03-31 | 2015-10-06 | Edward Wells Knowlton | Method for treatment of tissue |
ATE411836T1 (en) | 2003-05-19 | 2008-11-15 | Ust Inc | GEOMETRIC SHAPED HYDROGEL COUPLING BODY FOR HIGH-INTENSITY FOCUSED ULTRASOUND TREATMENT |
EP1628577A2 (en) | 2003-05-21 | 2006-03-01 | Dietrich, René | Ultrasound coupling medium for use in medical diagnostics |
ITSV20030023A1 (en) | 2003-05-22 | 2004-11-23 | Esaote Spa | METHOD FOR THE OPTIMIZATION OF ULTRASONIC IMPULSES IN |
US6896657B2 (en) | 2003-05-23 | 2005-05-24 | Scimed Life Systems, Inc. | Method and system for registering ultrasound image in three-dimensional coordinate system |
JP4041014B2 (en) | 2003-06-06 | 2008-01-30 | オリンパス株式会社 | Ultrasonic surgical device |
EP1635709B1 (en) | 2003-06-12 | 2013-10-30 | Bracco Suisse SA | Blood flow estimates through replenishment curve fitting in ultrasound contrast imaging |
CN100460032C (en) | 2003-06-13 | 2009-02-11 | 松下电工株式会社 | Ultrasound applying skin care device |
US7303555B2 (en) | 2003-06-30 | 2007-12-04 | Depuy Products, Inc. | Imaging and therapeutic procedure for carpal tunnel syndrome |
US20050033316A1 (en) | 2003-07-14 | 2005-02-10 | M. Glen Kertz | Ultrasonic skin cleaner |
US20050070961A1 (en) | 2003-07-15 | 2005-03-31 | Terumo Kabushiki Kaisha | Energy treatment apparatus |
US20050102009A1 (en) | 2003-07-31 | 2005-05-12 | Peter Costantino | Ultrasound treatment and imaging system |
JP4472395B2 (en) | 2003-08-07 | 2010-06-02 | オリンパス株式会社 | Ultrasonic surgery system |
WO2005015728A1 (en) | 2003-08-08 | 2005-02-17 | Matsushita Electric Industrial Co., Ltd. | Ultrasonic motor drive device and ultrasonic diagnosis apparatus |
US7398116B2 (en) | 2003-08-11 | 2008-07-08 | Veran Medical Technologies, Inc. | Methods, apparatuses, and systems useful in conducting image guided interventions |
US7294125B2 (en) | 2003-08-22 | 2007-11-13 | Scimed Life Systems, Inc. | Methods of delivering energy to body portions to produce a therapeutic response |
US20080086056A1 (en) | 2003-08-25 | 2008-04-10 | Industrial Technology Research Institute | Micro ultrasonic transducers |
US20050080469A1 (en) | 2003-09-04 | 2005-04-14 | Larson Eugene A. | Treatment of cardiac arrhythmia utilizing ultrasound |
WO2005025403A2 (en) | 2003-09-08 | 2005-03-24 | Board Of Trustees Of The University Of Arkansas | Ultrasound apparatus and method for augmented clot lysis |
US20050055018A1 (en) | 2003-09-08 | 2005-03-10 | Michael Kreindel | Method and device for sub-dermal tissue treatment |
DE20314479U1 (en) | 2003-09-13 | 2004-02-12 | Peter Krauth Gmbh | Low frequency ultrasound treatment unit for wet use has electronic unit with detachable connection to sealed titanium or stainless steel membrane ultrasound head |
FR2859983B1 (en) | 2003-09-22 | 2006-03-10 | Valois Sas | FIXING DEVICE AND MOUNTING METHOD FOR FIXING A DISTRIBUTION MEMBER ON A TANK OPENING |
US20050074407A1 (en) | 2003-10-01 | 2005-04-07 | Sonotech, Inc. | PVP and PVA as in vivo biocompatible acoustic coupling medium |
US20050085731A1 (en) | 2003-10-21 | 2005-04-21 | Miller David G. | Ultrasound transducer finger probe |
US7332985B2 (en) | 2003-10-30 | 2008-02-19 | Avago Technologies Wireless Ip (Singapore) Pte Ltd. | Cavity-less film bulk acoustic resonator (FBAR) devices |
US7296318B2 (en) | 2003-11-04 | 2007-11-20 | University Of Washington | Toothbrush employing an acoustic waveguide |
US20050113689A1 (en) | 2003-11-21 | 2005-05-26 | Arthur Gritzky | Method and apparatus for performing multi-mode imaging |
US20050131302A1 (en) | 2003-12-16 | 2005-06-16 | Poland Mckee D. | Ultrasonic probe having a selector switch |
US20110040171A1 (en) | 2003-12-16 | 2011-02-17 | University Of Washington | Image guided high intensity focused ultrasound treatment of nerves |
US20050137656A1 (en) | 2003-12-23 | 2005-06-23 | American Environmental Systems, Inc. | Acoustic-optical therapeutical devices and methods |
EP1699407A4 (en) | 2003-12-30 | 2010-12-01 | Medicis Technologies Corp | Ultrasound therapy head with movement control |
BRPI0418242A (en) | 2003-12-30 | 2007-04-17 | Liposonix Inc | transducer for ultrasound, transducer assemblies and interchangeable electronic medical instruments |
KR20060113930A (en) | 2003-12-30 | 2006-11-03 | 리포소닉스 인코포레이티드 | Systems and methods for the destruction of adipose tissue |
US20050154308A1 (en) | 2003-12-30 | 2005-07-14 | Liposonix, Inc. | Disposable transducer seal |
US7857773B2 (en) | 2003-12-30 | 2010-12-28 | Medicis Technologies Corporation | Apparatus and methods for the destruction of adipose tissue |
US20050193451A1 (en) | 2003-12-30 | 2005-09-01 | Liposonix, Inc. | Articulating arm for medical procedures |
US8343051B2 (en) | 2003-12-30 | 2013-01-01 | Liposonix, Inc. | Apparatus and methods for the destruction of adipose tissue |
US8337407B2 (en) | 2003-12-30 | 2012-12-25 | Liposonix, Inc. | Articulating arm for medical procedures |
WO2005065407A2 (en) | 2003-12-30 | 2005-07-21 | Liposonix, Inc. | Position tracking device |
US7905836B2 (en) | 2004-02-06 | 2011-03-15 | Technion Research And Development Foundation | Localized production of microbubbles and control of cavitational and heating effects by use of enhanced ultrasound |
CA2555396C (en) | 2004-02-06 | 2016-03-15 | Daniel Barolet | Method and device for the treatment of mammalian tissues |
JP2005245521A (en) | 2004-03-01 | 2005-09-15 | Japan Natural Laboratory Co Ltd | Skin care or beauty system using ion introducer, ultrasonic wave facial treatment device, and cosmetic additives |
US7662114B2 (en) | 2004-03-02 | 2010-02-16 | Focus Surgery, Inc. | Ultrasound phased arrays |
JP4453701B2 (en) | 2004-03-02 | 2010-04-21 | 株式会社村田製作所 | Surface acoustic wave device |
US20050193820A1 (en) | 2004-03-04 | 2005-09-08 | Siemens Medical Solutions Usa, Inc. | Integrated sensor and motion sensing for ultrasound and other devices |
EP2835642B1 (en) | 2004-03-12 | 2018-01-17 | University Of Virginia Patent Foundation | Electron transfer dissociation for biopolymer sequence analysis |
US20050228281A1 (en) | 2004-03-31 | 2005-10-13 | Nefos Thomas P | Handheld diagnostic ultrasound system with head mounted display |
BRPI0509744A (en) | 2004-04-09 | 2007-09-25 | Palomar Medical Tech Inc | methods and products for producing emr-treated islet lattices in fabrics and their uses |
JP4100372B2 (en) | 2004-05-10 | 2008-06-11 | 松下電工株式会社 | Ultrasonic beauty equipment |
US8235909B2 (en) | 2004-05-12 | 2012-08-07 | Guided Therapy Systems, L.L.C. | Method and system for controlled scanning, imaging and/or therapy |
JP2007537013A (en) | 2004-05-14 | 2007-12-20 | メドトロニック・インコーポレーテッド | Method for forming an ablated tissue region using high intensity focused ultrasound |
US7951095B2 (en) | 2004-05-20 | 2011-05-31 | Ethicon Endo-Surgery, Inc. | Ultrasound medical system |
US7806839B2 (en) | 2004-06-14 | 2010-10-05 | Ethicon Endo-Surgery, Inc. | System and method for ultrasound therapy using grating lobes |
US7837675B2 (en) | 2004-07-22 | 2010-11-23 | Shaser, Inc. | Method and device for skin treatment with replaceable photosensitive window |
JP2008507310A (en) | 2004-07-23 | 2008-03-13 | アサーム | Ultrasonic therapy apparatus and ultrasonic therapy method |
US7699780B2 (en) | 2004-08-11 | 2010-04-20 | Insightec—Image-Guided Treatment Ltd. | Focused ultrasound system with adaptive anatomical aperture shaping |
US7310928B2 (en) | 2004-08-24 | 2007-12-25 | Curry Janine V | Retractable spurs |
US7105986B2 (en) | 2004-08-27 | 2006-09-12 | General Electric Company | Ultrasound transducer with enhanced thermal conductivity |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
US7393325B2 (en) | 2004-09-16 | 2008-07-01 | Guided Therapy Systems, L.L.C. | Method and system for ultrasound treatment with a multi-directional transducer |
US7824348B2 (en) | 2004-09-16 | 2010-11-02 | Guided Therapy Systems, L.L.C. | System and method for variable depth ultrasound treatment |
US20080114254A1 (en) | 2004-09-19 | 2008-05-15 | Bioscan Ltd. | Intravascular Ultrasound Imaging Device |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US20150165243A1 (en) | 2004-09-24 | 2015-06-18 | Guided Therapy Systems, Llc | System and Method for Treating Cartilage and Injuries to Joints and Connective Tissue |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US7530958B2 (en) | 2004-09-24 | 2009-05-12 | Guided Therapy Systems, Inc. | Method and system for combined ultrasound treatment |
US20130096471A1 (en) | 2010-08-02 | 2013-04-18 | Guided Therapy Systems, Llc | Systems and methods for treating injuries to joints and connective tissue |
US20060111744A1 (en) | 2004-10-13 | 2006-05-25 | Guided Therapy Systems, L.L.C. | Method and system for treatment of sweat glands |
EP2279698A3 (en) | 2004-10-06 | 2014-02-19 | Guided Therapy Systems, L.L.C. | Method and system for non-invasive cosmetic enhancement of stretch marks |
JP5094402B2 (en) | 2004-10-06 | 2012-12-12 | ガイデッド セラピー システムズ, エル.エル.シー. | Method and system for ultrasonic tissue processing |
ES2705758T3 (en) | 2004-10-06 | 2019-03-26 | Guided Therapy Systems Llc | System for controlled heat treatment of human surface tissue |
US7530356B2 (en) | 2004-10-06 | 2009-05-12 | Guided Therapy Systems, Inc. | Method and system for noninvasive mastopexy |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US7758524B2 (en) | 2004-10-06 | 2010-07-20 | Guided Therapy Systems, L.L.C. | Method and system for ultra-high frequency ultrasound treatment |
US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US8690778B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Energy-based tissue tightening |
US20120046547A1 (en) | 2004-10-06 | 2012-02-23 | Guided Therapy Systems, Llc | System and method for cosmetic treatment |
US20150217141A1 (en) | 2004-10-06 | 2015-08-06 | Guided Therapy Systems, Llc | Energy-based tissue tightening system |
US20060079868A1 (en) | 2004-10-07 | 2006-04-13 | Guided Therapy Systems, L.L.C. | Method and system for treatment of blood vessel disorders |
US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
US20060089688A1 (en) | 2004-10-25 | 2006-04-27 | Dorin Panescu | Method and apparatus to reduce wrinkles through application of radio frequency energy to nerves |
US20060094988A1 (en) | 2004-10-28 | 2006-05-04 | Tosaya Carol A | Ultrasonic apparatus and method for treating obesity or fat-deposits or for delivering cosmetic or other bodily therapy |
US20060122509A1 (en) | 2004-11-24 | 2006-06-08 | Liposonix, Inc. | System and methods for destroying adipose tissue |
US20060116583A1 (en) | 2004-11-26 | 2006-06-01 | Yoichi Ogasawara | Ultrasonic diagnostic apparatus and control method thereof |
US8162858B2 (en) | 2004-12-13 | 2012-04-24 | Us Hifu, Llc | Ultrasonic medical treatment device with variable focal zone |
JP4095639B2 (en) | 2004-12-22 | 2008-06-04 | キヤノン株式会社 | Image processing apparatus and image processing apparatus control method |
CN100542635C (en) | 2005-01-10 | 2009-09-23 | 重庆海扶(Hifu)技术有限公司 | High intensity focused ultrasound therapy device and method |
US7918795B2 (en) | 2005-02-02 | 2011-04-05 | Gynesonics, Inc. | Method and device for uterine fibroid treatment |
US7553284B2 (en) | 2005-02-02 | 2009-06-30 | Vaitekunas Jeffrey J | Focused ultrasound for pain reduction |
JP2008529580A (en) | 2005-02-06 | 2008-08-07 | ウルトラシェイプ エルティーディー. | Non-thermal sonic texture modification |
US20060241440A1 (en) | 2005-02-07 | 2006-10-26 | Yoram Eshel | Non-thermal acoustic tissue modification |
US7537240B2 (en) | 2005-02-22 | 2009-05-26 | Automotive Systems Laboratory, Inc. | Gas generating system |
US7771418B2 (en) | 2005-03-09 | 2010-08-10 | Sunnybrook Health Sciences Centre | Treatment of diseased tissue using controlled ultrasonic heating |
US7931611B2 (en) | 2005-03-23 | 2011-04-26 | Misonix, Incorporated | Ultrasonic wound debrider probe and method of use |
US20060224090A1 (en) | 2005-03-29 | 2006-10-05 | Isaac Ostrovsky | Apparatus and method for stiffening tissue |
US7335997B2 (en) | 2005-03-31 | 2008-02-26 | Ethicon Endo-Surgery, Inc. | System for controlling ultrasonic clamping and cutting instruments |
US7571336B2 (en) | 2005-04-25 | 2009-08-04 | Guided Therapy Systems, L.L.C. | Method and system for enhancing safety with medical peripheral device by monitoring if host computer is AC powered |
US7909836B2 (en) | 2005-05-20 | 2011-03-22 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8454511B2 (en) | 2005-05-27 | 2013-06-04 | Board Of Regents, The University Of Texas System | Magneto-motive ultrasound detection of magnetic nanoparticles |
US8038631B1 (en) | 2005-06-01 | 2011-10-18 | Sanghvi Narendra T | Laparoscopic HIFU probe |
US20070016039A1 (en) | 2005-06-21 | 2007-01-18 | Insightec-Image Guided Treatment Ltd. | Controlled, non-linear focused ultrasound treatment |
US7785277B2 (en) | 2005-06-23 | 2010-08-31 | Celleration, Inc. | Removable applicator nozzle for ultrasound wound therapy device |
US7330578B2 (en) | 2005-06-23 | 2008-02-12 | Accuray Inc. | DRR generation and enhancement using a dedicated graphics device |
US8182428B2 (en) | 2005-07-26 | 2012-05-22 | Surf Technology As | Dual frequency band ultrasound transducer arrays |
US7955262B2 (en) | 2005-07-26 | 2011-06-07 | Syneron Medical Ltd. | Method and apparatus for treatment of skin using RF and ultrasound energies |
LT1912749T (en) | 2005-07-26 | 2021-10-25 | Surf Technology As | Dual frequency band ultrasound transducer arrays |
WO2007019365A2 (en) | 2005-08-03 | 2007-02-15 | Massachusetts Eye & Ear Infirmary | Targeted muscle ablation for reducing signs of aging |
US7621873B2 (en) | 2005-08-17 | 2009-11-24 | University Of Washington | Method and system to synchronize acoustic therapy with ultrasound imaging |
US20070065420A1 (en) | 2005-08-23 | 2007-03-22 | Johnson Lanny L | Ultrasound Therapy Resulting in Bone Marrow Rejuvenation |
US7517315B2 (en) | 2005-08-26 | 2009-04-14 | Boston Scientific Scimed, Inc. | System and method for determining the proximity between a medical probe and a tissue surface |
US8057408B2 (en) | 2005-09-22 | 2011-11-15 | The Regents Of The University Of Michigan | Pulsed cavitational ultrasound therapy |
US20070083120A1 (en) | 2005-09-22 | 2007-04-12 | Cain Charles A | Pulsed cavitational ultrasound therapy |
WO2007037619A1 (en) | 2005-09-27 | 2007-04-05 | Medison Co., Ltd. | Probe for ultrasound diagnosis and ultrasound diagnostic system using the same |
US20070088346A1 (en) | 2005-10-14 | 2007-04-19 | Mirizzi Michael S | Method and apparatus for varicose vein treatment using acoustic hemostasis |
US8357095B2 (en) | 2005-10-20 | 2013-01-22 | The General Hospital Corporation | Non-invasive treatment of fascia |
WO2007051261A1 (en) | 2005-11-07 | 2007-05-10 | Signostics Pty Ltd | Ultrasound measurement system and method |
DE102005053918A1 (en) | 2005-11-11 | 2007-05-16 | Zimmer Elektromedizin Gmbh | Method and device for irradiating ultrasound in tissue |
US20080146970A1 (en) | 2005-12-06 | 2008-06-19 | Julia Therapeutics, Llc | Gel dispensers for treatment of skin with acoustic energy |
US8287337B2 (en) | 2006-01-11 | 2012-10-16 | Hcr Incorporated | Cold storage doorway with airflow control system and method |
US9017717B2 (en) | 2006-01-16 | 2015-04-28 | Peach Technologies Llc | Bandage for facilitating transdermal respiration and healing |
BRPI0706605B8 (en) | 2006-01-17 | 2021-06-22 | Endymed Medical Ltd | electrosurgical system employing phase-controlled radiofrequency energy |
US8133191B2 (en) | 2006-02-16 | 2012-03-13 | Syneron Medical Ltd. | Method and apparatus for treatment of adipose tissue |
US20090048514A1 (en) | 2006-03-09 | 2009-02-19 | Slender Medical Ltd. | Device for ultrasound monitored tissue treatment |
US7828734B2 (en) | 2006-03-09 | 2010-11-09 | Slender Medical Ltd. | Device for ultrasound monitored tissue treatment |
US20110251524A1 (en) | 2006-03-09 | 2011-10-13 | Slender Medical, Ltd. | Device for ultrasound treatment and monitoring tissue treatment |
US9107798B2 (en) | 2006-03-09 | 2015-08-18 | Slender Medical Ltd. | Method and system for lipolysis and body contouring |
US8920320B2 (en) | 2006-03-10 | 2014-12-30 | Liposonix, Inc. | Methods and apparatus for coupling a HIFU transducer to a skin surface |
ITBO20060221A1 (en) | 2006-03-30 | 2006-06-29 | Massimo Santangelo | METHOD AND EQUIPMENT TO INDUCE OSTEOGENESIS IN A BONE REGION OF THE PATIENT. |
US20070239079A1 (en) | 2006-04-07 | 2007-10-11 | The General Hospital Corporation | Method and apparatus for selective treatment of biological tissue using ultrasound energy |
JP3123559U (en) | 2006-05-10 | 2006-07-20 | ニチハ株式会社 | Makeup corner material |
US20070264625A1 (en) | 2006-05-11 | 2007-11-15 | Reliant Technologies, Inc. | Apparatus and Method for Ablation-Related Dermatological Treatment of Selected Targets |
FR2903316B1 (en) | 2006-07-05 | 2009-06-26 | Edap S A | THERAPY PROBE AND THERAPY APPARATUS INCLUDING SUCH A PROBE |
US20100030076A1 (en) | 2006-08-01 | 2010-02-04 | Kobi Vortman | Systems and Methods for Simultaneously Treating Multiple Target Sites |
US20080039724A1 (en) | 2006-08-10 | 2008-02-14 | Ralf Seip | Ultrasound transducer with improved imaging |
FR2905277B1 (en) | 2006-08-29 | 2009-04-17 | Centre Nat Rech Scient | DEVICE FOR THE VOLUMIC TREATMENT OF BIOLOGICAL TISSUES |
US20080097214A1 (en) | 2006-09-05 | 2008-04-24 | Capistrano Labs, Inc. | Ophthalmic ultrasound probe assembly |
US20080195000A1 (en) | 2006-09-06 | 2008-08-14 | Spooner Gregory J R | System and Method for Dermatological Treatment Using Ultrasound |
US20080183110A1 (en) | 2006-09-06 | 2008-07-31 | Davenport Scott A | Ultrasound system and method for hair removal |
US8262591B2 (en) | 2006-09-07 | 2012-09-11 | Nivasonix, Llc | External ultrasound lipoplasty |
US7955281B2 (en) | 2006-09-07 | 2011-06-07 | Nivasonix, Llc | External ultrasound lipoplasty |
US8334637B2 (en) | 2006-09-18 | 2012-12-18 | Liposonix, Inc. | Transducer with shield |
US7652411B2 (en) | 2006-09-18 | 2010-01-26 | Medicis Technologies Corporation | Transducer with shield |
US9566454B2 (en) | 2006-09-18 | 2017-02-14 | Guided Therapy Systems, Llc | Method and sysem for non-ablative acne treatment and prevention |
ES2579765T3 (en) | 2006-09-19 | 2016-08-16 | Guided Therapy Systems, L.L.C. | System for the treatment of muscle, tendon, ligamentous and cartilaginous tissue |
US9241683B2 (en) | 2006-10-04 | 2016-01-26 | Ardent Sound Inc. | Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid |
US20080183077A1 (en) | 2006-10-19 | 2008-07-31 | Siemens Corporate Research, Inc. | High intensity focused ultrasound path determination |
US8758253B2 (en) | 2006-11-08 | 2014-06-24 | Hitachi Medical Corporation | Ultrasonic probe and ultrasonic diagnostic apparatus using the same |
US8656783B2 (en) | 2006-11-10 | 2014-02-25 | Siemens Medical Solutions Usa, Inc. | Transducer array imaging system |
US20100056925A1 (en) | 2006-11-28 | 2010-03-04 | Chongqing Ronghai Medical Ultrasound Industry Ltd. | Ultrasonic Therapeutic Device Capable of Multipoint Transmitting |
US9492686B2 (en) | 2006-12-04 | 2016-11-15 | Koninklijke Philips N.V. | Devices and methods for treatment of skin conditions |
US8382689B2 (en) | 2007-02-08 | 2013-02-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Device and method for high intensity focused ultrasound ablation with acoustic lens |
US20120046553A9 (en) | 2007-01-18 | 2012-02-23 | General Electric Company | Ultrasound catheter housing with electromagnetic shielding properties and methods of manufacture |
US9706976B2 (en) | 2007-02-08 | 2017-07-18 | Siemens Medical Solutions Usa, Inc. | Ultrasound imaging systems and methods of performing ultrasound procedures |
US8231533B2 (en) | 2007-02-16 | 2012-07-31 | Buchalter Neal | Ultrasound coupling device |
DK1970059T3 (en) | 2007-03-12 | 2009-12-21 | Dobavet Gmbh | Calcium dobesilate drug for the treatment and prophylaxis of tendon disorders |
US8273037B2 (en) | 2007-03-19 | 2012-09-25 | Syneron Medical Ltd | Method and system for soft tissue destruction |
US8142200B2 (en) | 2007-03-26 | 2012-03-27 | Liposonix, Inc. | Slip ring spacer and method for its use |
EP2532320A3 (en) | 2007-04-19 | 2013-04-03 | Miramar Labs, Inc. | Apparatus for reducing sweat production |
US8038619B2 (en) | 2007-04-30 | 2011-10-18 | General Electric Company | Motor driver for ultrasound system |
JP2010526589A (en) | 2007-05-07 | 2010-08-05 | ガイデッド セラピー システムズ, エル.エル.シー. | Method and system for modulating a mediant using acoustic energy |
PT2152167T (en) | 2007-05-07 | 2018-12-10 | Guided Therapy Systems Llc | Methods and systems for coupling and focusing acoustic energy using a coupler member |
US20150174388A1 (en) | 2007-05-07 | 2015-06-25 | Guided Therapy Systems, Llc | Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue |
WO2008144274A2 (en) | 2007-05-14 | 2008-11-27 | Sono Esthetx, Inc. | Method, system, and apparatus for line-focused ultrasound therapy |
RU2502470C2 (en) | 2007-06-01 | 2013-12-27 | Конинклейке Филипс Электроникс, Н.В. | Light-weight wireless ultrasonic sensor |
CN101784236A (en) | 2007-07-26 | 2010-07-21 | 赛诺龙医疗公司 | A method and apparatus for ultrasound tissue treatment |
WO2009023568A1 (en) | 2007-08-10 | 2009-02-19 | Eleme Medical Inc. | Multi-module skin or body treatment device and the method of using |
US7631611B1 (en) | 2007-08-21 | 2009-12-15 | The United States Of America As Represented By The Secretary Of The Navy | Underwater vehicle |
US8235902B2 (en) | 2007-09-11 | 2012-08-07 | Focus Surgery, Inc. | System and method for tissue change monitoring during HIFU treatment |
EP2254477B1 (en) | 2007-09-28 | 2013-05-29 | Nivasonix, LLC. | Handheld transducer scanning speed guides and position detectors |
EP2209424A1 (en) | 2007-10-09 | 2010-07-28 | Cabochon Aesthetics, Inc. | Ultrasound apparatus with treatment lens |
US20100274161A1 (en) | 2007-10-15 | 2010-10-28 | Slender Medical, Ltd. | Implosion techniques for ultrasound |
WO2009073884A1 (en) | 2007-12-06 | 2009-06-11 | Measurement Specialties, Inc. | Multilayer backing absorber for ultrasonic transducer |
US20090163807A1 (en) | 2007-12-21 | 2009-06-25 | Sliwa John W | Finger-mounted or robot-mounted transducer device |
US20090177123A1 (en) | 2007-12-28 | 2009-07-09 | Celleration, Inc. | Methods for treating inflammatory disorders |
EP2231279A1 (en) | 2007-12-28 | 2010-09-29 | Celleration, Inc. | Methods for treating inflammatory skin disorders |
CN101959556B (en) | 2008-02-01 | 2013-11-27 | 麦迪斯技术公司 | Therapy head for use with ultrasound system |
US20090198157A1 (en) | 2008-02-01 | 2009-08-06 | Eilaz Babaev | Ultrasound moxibustion method and device |
US8461108B2 (en) | 2008-03-07 | 2013-06-11 | Myoscience, Inc. | Subdermal tissue remodeling using myostatin, methods and related systems |
US20090230823A1 (en) | 2008-03-13 | 2009-09-17 | Leonid Kushculey | Operation of patterned ultrasonic transducers |
KR102352609B1 (en) | 2008-06-06 | 2022-01-18 | 얼테라, 인크 | Ultrasound treatment system |
US20090312693A1 (en) | 2008-06-13 | 2009-12-17 | Vytronus, Inc. | System and method for delivering energy to tissue |
US20100022919A1 (en) | 2008-07-22 | 2010-01-28 | Celleration, Inc. | Methods of Skin Grafting Using Ultrasound |
US20100042020A1 (en) | 2008-08-13 | 2010-02-18 | Shmuel Ben-Ezra | Focused energy delivery apparatus method and system |
WO2010029555A1 (en) | 2008-09-12 | 2010-03-18 | Slender Medical, Ltd. | Virtual ultrasonic scissors |
US20100113983A1 (en) | 2008-10-31 | 2010-05-06 | Microsoft Corporation | Utilizing ultrasound to disrupt pathogens |
US20100130891A1 (en) | 2008-11-21 | 2010-05-27 | Taggart Rebecca M | Wearable Therapeutic Ultrasound Article |
US8585618B2 (en) | 2008-12-22 | 2013-11-19 | Cutera, Inc. | Broad-area irradiation of small near-field targets using ultrasound |
JP2012513837A (en) | 2008-12-24 | 2012-06-21 | ガイデッド セラピー システムズ, エルエルシー | Method and system for fat loss and / or cellulite treatment |
US20100191120A1 (en) | 2009-01-28 | 2010-07-29 | General Electric Company | Apparatus and method for controlling an ultrasound system based on contact with an ultrasound probe |
AR076081A1 (en) | 2009-03-04 | 2011-05-18 | Medicis Technologies Corp | PROVISION FOR THE TREATMENT BY ULTRASOUND OF TISSUE ADIPOSE TO MULTIPLE DEPTHS |
US8486001B2 (en) | 2009-03-12 | 2013-07-16 | Tim Weyant | Method of treating capsular contracture |
US7905007B2 (en) | 2009-03-18 | 2011-03-15 | General Electric Company | Method for forming a matching layer structure of an acoustic stack |
US8208346B2 (en) | 2009-03-23 | 2012-06-26 | Liposonix, Inc. | Selectable tuning transformer |
US8298163B1 (en) | 2009-05-01 | 2012-10-30 | Body Beam Research Inc. | Non-invasive ultrasonic soft-tissue treatment apparatus |
US20100286518A1 (en) | 2009-05-11 | 2010-11-11 | General Electric Company | Ultrasound system and method to deliver therapy based on user defined treatment spaces |
US20120123304A1 (en) | 2009-06-16 | 2012-05-17 | Wavomed Ltd. | Moving standing waves |
EP2461752B1 (en) | 2009-08-07 | 2017-03-15 | Thayer Intellectual Property Inc. | Systems for treatment of compressed nerves |
US20120143100A1 (en) | 2009-08-14 | 2012-06-07 | University Of Southern California | Extended depth-of-focus high intensity ultrasonic transducer |
US9114245B2 (en) | 2009-08-14 | 2015-08-25 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical apparatus and methods for use thereof |
AU2010284313B2 (en) | 2009-08-17 | 2016-01-28 | Histosonics, Inc. | Disposable acoustic coupling medium container |
US8264126B2 (en) | 2009-09-01 | 2012-09-11 | Measurement Specialties, Inc. | Multilayer acoustic impedance converter for ultrasonic transducers |
US8932238B2 (en) | 2009-09-29 | 2015-01-13 | Liposonix, Inc. | Medical ultrasound device with liquid dispensing device coupled to a therapy head |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US20110190745A1 (en) | 2009-12-04 | 2011-08-04 | Uebelhoer Nathan S | Treatment of sweat glands |
US20110144490A1 (en) | 2009-12-10 | 2011-06-16 | General Electric Company | Devices and methods for adipose tissue reduction and skin contour irregularity smoothing |
US20110319794A1 (en) | 2010-01-15 | 2011-12-29 | Michael Gertner | Convective Energy Transfer into the Eye |
US8398549B2 (en) | 2010-02-16 | 2013-03-19 | Duke University | Ultrasound methods, systems and computer program products for imaging contrasting objects using combined images |
US20110270137A1 (en) | 2010-04-29 | 2011-11-03 | Applisonix Ltd. | Method and system for treating skin tissue |
WO2011138722A1 (en) | 2010-05-03 | 2011-11-10 | Andrey Rybyanets | Resonantly amplified shear waves |
FR2960789B1 (en) | 2010-06-07 | 2013-07-19 | Image Guided Therapy | ULTRASOUND TRANSDUCER FOR MEDICAL USE |
WO2012006053A1 (en) | 2010-06-29 | 2012-01-12 | Kullervo Henrik Hynynen | Thermal therapy apparatus and method using focused ultrasonic sound fields |
TW201208734A (en) | 2010-07-24 | 2012-03-01 | Medicis Technologies Corp | Apparatus and methods for non-invasive body contouring |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US10183182B2 (en) | 2010-08-02 | 2019-01-22 | Guided Therapy Systems, Llc | Methods and systems for treating plantar fascia |
US8686335B2 (en) | 2011-12-31 | 2014-04-01 | Seno Medical Instruments, Inc. | System and method for adjusting the light output of an optoacoustic imaging system |
US8573392B2 (en) | 2010-09-22 | 2013-11-05 | Liposonix, Inc. | Modified atmosphere packaging for ultrasound transducer cartridge |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
US20120191020A1 (en) | 2011-01-25 | 2012-07-26 | Shuki Vitek | Uniform thermal treatment of tissue interfaces |
US8968205B2 (en) | 2011-02-10 | 2015-03-03 | Siemens Medical Solutions Usa, Inc. | Sub-aperture control in high intensity focused ultrasound |
US20120271202A1 (en) | 2011-03-23 | 2012-10-25 | Cutera, Inc. | Ultrasonic therapy device with diffractive focusing |
FR2973250B1 (en) | 2011-03-29 | 2015-01-02 | Edap Tms France | THERAPY PROBE FOR TREATING TISSUE THROUGH CROSS-FOCUSED ULTRASONIC WAVE |
EP2709726B1 (en) | 2011-05-19 | 2015-11-04 | Alma Lasers Ltd | Apparatus for concurrent treatment with ultrasonic energy and thermal rf energy |
US20120296240A1 (en) | 2011-05-20 | 2012-11-22 | Slender Medical Ltd. | Ultrasound eye bag treatment |
KR20120131552A (en) | 2011-05-25 | 2012-12-05 | 삼성전자주식회사 | Method and system for diagnosis and treatment using ultrasound |
US20120330283A1 (en) | 2011-06-23 | 2012-12-27 | Elwha LLC, a limited liability company of the State of Delaware | Systems, devices, and methods to induce programmed cell death in adipose tissue |
US8752467B2 (en) | 2011-06-30 | 2014-06-17 | Elwha Llc | Wearable air blast protection device having at least two attenuating regions |
US9452302B2 (en) | 2011-07-10 | 2016-09-27 | Guided Therapy Systems, Llc | Systems and methods for accelerating healing of implanted material and/or native tissue |
EP2731675B1 (en) | 2011-07-11 | 2023-05-03 | Guided Therapy Systems, L.L.C. | Systems and methods for coupling an ultrasound source to tissue |
KR20130009138A (en) | 2011-07-14 | 2013-01-23 | 삼성전자주식회사 | Focused ultrasound therapy apparatus and focal point controlling method thereof |
US8583211B2 (en) | 2011-08-10 | 2013-11-12 | Siemens Aktiengesellschaft | Method for temperature control in magnetic resonance-guided volumetric ultrasound therapy |
KR20130026327A (en) | 2011-09-05 | 2013-03-13 | 삼성전자주식회사 | Medical treatment apparutus using ultrasound and controlling method thereof |
US20130066237A1 (en) | 2011-09-09 | 2013-03-14 | Palomar Medical Technologies, Inc. | Methods and devices for inflammation treatment |
US8954155B2 (en) | 2011-09-19 | 2015-02-10 | Biotalk Technologies Inc | Apparatus and method for rejuvenating skin |
WO2013048912A2 (en) | 2011-09-26 | 2013-04-04 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US20130338475A1 (en) | 2012-06-13 | 2013-12-19 | Seno Medical Instruments, Inc. | Optoacoustic imaging system with fiber optic cable |
US9392992B2 (en) | 2012-02-28 | 2016-07-19 | Siemens Medical Solutions Usa, Inc. | High intensity focused ultrasound registration with imaging |
US8836203B2 (en) | 2012-03-30 | 2014-09-16 | Measurement Specialties, Inc. | Signal return for ultrasonic transducers |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
US20130296743A1 (en) | 2012-05-02 | 2013-11-07 | Siemens Medical Solutions Usa, Inc. | Ultrasound for Therapy Control or Monitoring |
KR101365946B1 (en) | 2012-05-07 | 2014-02-24 | 주식회사 하이로닉 | High intensity focused ultrasound generating device for the deduction of fat tissue |
EP2857066A4 (en) | 2012-05-29 | 2016-03-23 | Lissot Mailin Auxiliadora Franco | Method and apparatus for treating periprosthetic capsular contracture |
BR112015005842A2 (en) | 2012-09-20 | 2017-07-04 | Koninklijke Philips Nv | method of treating an area of skin tissue, and apparatus for treating an area of skin tissue |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US20150258351A1 (en) | 2012-10-02 | 2015-09-17 | Ardent Sound, Inc. | Motion Mechanisms for Ultrasound Transducer Modules |
JP6496662B2 (en) | 2012-10-12 | 2019-04-03 | プロファウンド メディカル インク | Multi-focus ultrasound irradiation for hyperthermia treatment using magnetic resonance guided focused ultrasound |
WO2014127091A1 (en) | 2013-02-14 | 2014-08-21 | Thync, Inc. | Transcranial ultrasound systems |
KR102189678B1 (en) | 2013-02-15 | 2020-12-11 | 삼성전자주식회사 | A method, apparatus and HIFU system for generating ultrasound forming multi-focuses using medical image in region of interest |
KR101335476B1 (en) | 2013-02-25 | 2013-12-11 | 주식회사 코러스트 | Line-focus type ultrasound transducer and high intensity focused ultrasound generating apparatus including the same |
CN113648551A (en) | 2013-03-08 | 2021-11-16 | 奥赛拉公司 | Apparatus and method for multi-focal ultrasound therapy |
WO2014207665A2 (en) | 2013-06-28 | 2014-12-31 | Koninklijke Philips N.V. | Transducer placement and registration for image-guided sonothrombolysis |
US20150164734A1 (en) | 2013-12-12 | 2015-06-18 | Guided Therapy Systems, Llc | System and Method for Cosmetic Enhancement of Lips |
WO2015089425A1 (en) | 2013-12-13 | 2015-06-18 | Guided Therapy Systems, Llc | System and method for non-invasive treatment with improved efficiency |
EP3096838B1 (en) | 2014-01-20 | 2022-11-16 | Guided Therapy Systems, LLC | Systems for controlling acoustic energy deposition in various media |
US10272272B2 (en) | 2014-03-18 | 2019-04-30 | Hironic Co., Ltd. | High-intensity focused ultrasound operation device and operation method thereof |
MX371246B (en) | 2014-04-18 | 2020-01-22 | Ulthera Inc | Band transducer ultrasound therapy. |
PT3154633T (en) | 2014-06-13 | 2019-03-14 | Guided Therapy Systems Llc | System for fast ultrasound treatment |
WO2015200762A1 (en) | 2014-06-27 | 2015-12-30 | Guided Therapy Systems, Llc | Methods and systems for tattoo removal |
WO2016054155A1 (en) | 2014-09-30 | 2016-04-07 | Primegen Biotech, Llc. | Treatment of fibrosis using deep tissue heating and stem cell therapy |
WO2016118595A1 (en) | 2015-01-20 | 2016-07-28 | Guided Therapy Systems, Llc | Methods and systems for removal of a targeted tissue from the body |
US10624660B2 (en) | 2015-01-20 | 2020-04-21 | Guided Therapy Systems, Llc | Methods and systems for removal of a foreign object from tissue |
US10765851B2 (en) | 2015-03-03 | 2020-09-08 | Guided Therapy Systems Llc | Methods and systems for material transport across an impermeable or semi-permeable membrane via artificially created microchannels |
US20160296769A1 (en) | 2015-04-08 | 2016-10-13 | Guided Therapy Systems, Llc | System and Method for Increased Control of Ultrasound Treatments |
WO2017127328A1 (en) | 2016-01-18 | 2017-07-27 | Ulthera, Inc. | Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board and method of assembly thereof |
CA3016756C (en) | 2016-03-03 | 2023-03-21 | Alma Lasers Ltd. | Sonotrode |
JP7266795B2 (en) | 2016-03-23 | 2023-05-01 | ソリトン, インコーポレイテッド | Pulsed Acoustic Skin Clearing System and Method |
IL308833A (en) | 2016-06-06 | 2024-01-01 | Sofwave Medical Ltd | Ultrasound transducer and system |
RU2748788C2 (en) | 2016-08-16 | 2021-05-31 | Ультера, Инк. | Systems and methods for cosmetic ultrasonic skin treatment |
-
2005
- 2005-10-06 US US11/163,152 patent/US20060111744A1/en not_active Abandoned
-
2012
- 2012-04-11 US US13/444,485 patent/US8282554B2/en active Active
- 2012-09-04 US US13/603,279 patent/US8523775B2/en active Active
- 2012-09-04 US US13/603,159 patent/US8333700B1/en active Active
-
2013
- 2013-07-25 US US13/950,728 patent/US8932224B2/en active Active
-
2014
- 2014-12-16 US US14/571,835 patent/US9421029B2/en active Active
-
2016
- 2016-08-22 US US15/243,081 patent/US10046181B2/en active Active
-
2018
- 2018-07-30 US US16/049,364 patent/US10960235B2/en active Active
Patent Citations (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4039312A (en) * | 1972-07-04 | 1977-08-02 | Marcel Joseph Gaston Patru | Bacteriostatic, fungistatic and algicidal compositions, particularly for submarine paints |
US3913386A (en) * | 1973-01-16 | 1975-10-21 | Commissariat Energie Atomique | Method of compensation for the angle of refraction of an ultrasonic beam and a device for the application of said method |
US3992925A (en) * | 1973-12-10 | 1976-11-23 | U.S. Philips Corporation | Device for ultrasonic scanning |
US3965455A (en) * | 1974-04-25 | 1976-06-22 | The United States Of America As Represented By The Secretary Of The Navy | Focused arc beam transducer-reflector |
US4059098A (en) * | 1975-07-21 | 1977-11-22 | Stanford Research Institute | Flexible ultrasound coupling system |
US4101795A (en) * | 1976-10-25 | 1978-07-18 | Matsushita Electric Industrial Company | Ultrasonic probe |
US4213344A (en) * | 1978-10-16 | 1980-07-22 | Krautkramer-Branson, Incorporated | Method and apparatus for providing dynamic focussing and beam steering in an ultrasonic apparatus |
US4276491A (en) * | 1979-10-02 | 1981-06-30 | Ausonics Pty. Limited | Focusing piezoelectric ultrasonic medical diagnostic system |
US4343301A (en) * | 1979-10-04 | 1982-08-10 | Robert Indech | Subcutaneous neural stimulation or local tissue destruction |
US4325381A (en) * | 1979-11-21 | 1982-04-20 | New York Institute Of Technology | Ultrasonic scanning head with reduced geometrical distortion |
US4315514A (en) * | 1980-05-08 | 1982-02-16 | William Drewes | Method and apparatus for selective cell destruction |
US4381787A (en) * | 1980-08-15 | 1983-05-03 | Technicare Corporation | Ultrasound imaging system combining static B-scan and real-time sector scanning capability |
US4484569A (en) * | 1981-03-13 | 1984-11-27 | Riverside Research Institute | Ultrasonic diagnostic and therapeutic transducer assembly and method for using |
US4381007A (en) * | 1981-04-30 | 1983-04-26 | The United States Of America As Represented By The United States Department Of Energy | Multipolar corneal-shaping electrode with flexible removable skirt |
US4586512A (en) * | 1981-06-26 | 1986-05-06 | Thomson-Csf | Device for localized heating of biological tissues |
US4409839A (en) * | 1981-07-01 | 1983-10-18 | Siemens Ag | Ultrasound camera |
US4397314A (en) * | 1981-08-03 | 1983-08-09 | Clini-Therm Corporation | Method and apparatus for controlling and optimizing the heating pattern for a hyperthermia system |
US4441486A (en) * | 1981-10-27 | 1984-04-10 | Board Of Trustees Of Leland Stanford Jr. University | Hyperthermia system |
US4528979A (en) * | 1982-03-18 | 1985-07-16 | Kievsky Nauchno-Issledovatelsky Institut Otolaringologii Imeni Professora A.S. Kolomiiobenka | Cryo-ultrasonic surgical instrument |
US4452084A (en) * | 1982-10-25 | 1984-06-05 | Sri International | Inherent delay line ultrasonic transducer and systems |
US4646756A (en) * | 1982-10-26 | 1987-03-03 | The University Of Aberdeen | Ultra sound hyperthermia device |
US4513749A (en) * | 1982-11-18 | 1985-04-30 | Board Of Trustees Of Leland Stanford University | Three-dimensional temperature probe |
US4527550A (en) * | 1983-01-28 | 1985-07-09 | The United States Of America As Represented By The Department Of Health And Human Services | Helical coil for diathermy apparatus |
US4668516A (en) * | 1983-03-30 | 1987-05-26 | Alain Duraffourd | Composition for regenerating the collagen of connective skin tissue and a process for its preparation |
US4601296A (en) * | 1983-10-07 | 1986-07-22 | Yeda Research And Development Co., Ltd. | Hyperthermia apparatus |
US5150711A (en) * | 1983-12-14 | 1992-09-29 | Edap International, S.A. | Ultra-high-speed extracorporeal ultrasound hyperthermia treatment device |
US5143074A (en) * | 1983-12-14 | 1992-09-01 | Edap International | Ultrasonic treatment device using a focussing and oscillating piezoelectric element |
US4567895A (en) * | 1984-04-02 | 1986-02-04 | Advanced Technology Laboratories, Inc. | Fully wetted mechanical ultrasound scanhead |
US4697588A (en) * | 1984-12-27 | 1987-10-06 | Siemens Aktiengesellschaft | Shock wave tube for the fragmentation of concrements |
US4757820A (en) * | 1985-03-15 | 1988-07-19 | Kabushiki Kaisha Toshiba | Ultrasound therapy system |
US4663358A (en) * | 1985-05-01 | 1987-05-05 | Biomaterials Universe, Inc. | Porous and transparent poly(vinyl alcohol) gel and method of manufacturing the same |
US4865042A (en) * | 1985-08-16 | 1989-09-12 | Hitachi, Ltd. | Ultrasonic irradiation system |
US5304169A (en) * | 1985-09-27 | 1994-04-19 | Laser Biotech, Inc. | Method for collagen shrinkage |
US4874562A (en) * | 1986-02-13 | 1989-10-17 | Biomaterials Universe, Inc. | Method of molding a polyvinyl alcohol contact lens |
US4958626A (en) * | 1986-04-22 | 1990-09-25 | Nippon Oil Co., Ltd. | Method for applying electromagnetic wave and ultrasonic wave therapies |
US4875487A (en) * | 1986-05-02 | 1989-10-24 | Varian Associates, Inc. | Compressional wave hyperthermia treating method and apparatus |
US4807633A (en) * | 1986-05-21 | 1989-02-28 | Indianapolis Center For Advanced Research | Non-invasive tissue thermometry system and method |
US4867169A (en) * | 1986-07-29 | 1989-09-19 | Kaoru Machida | Attachment attached to ultrasound probe for clinical application |
US4865041A (en) * | 1987-02-04 | 1989-09-12 | Siemens Aktiengesellschaft | Lithotripter having an ultrasound locating system integrated therewith |
US4979501A (en) * | 1987-05-19 | 1990-12-25 | Vissh Voennomedicinski Institut | Method and apparatus for medical treatment of the pathological state of bones |
US5230338A (en) * | 1987-11-10 | 1993-07-27 | Allen George S | Interactive image-guided surgical system for displaying images corresponding to the placement of a surgical tool or the like |
US4917096A (en) * | 1987-11-25 | 1990-04-17 | Laboratory Equipment, Corp. | Portable ultrasonic probe |
US4860732A (en) * | 1987-11-25 | 1989-08-29 | Olympus Optical Co., Ltd. | Endoscope apparatus provided with endoscope insertion aid |
US5163421A (en) * | 1988-01-22 | 1992-11-17 | Angiosonics, Inc. | In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging |
US5143063A (en) * | 1988-02-09 | 1992-09-01 | Fellner Donald G | Method of removing adipose tissue from the body |
US5036855A (en) * | 1988-03-02 | 1991-08-06 | Laboratory Equipment, Corp. | Localization and therapy system for treatment of spatially oriented focal disease |
US4858613A (en) * | 1988-03-02 | 1989-08-22 | Laboratory Equipment, Corp. | Localization and therapy system for treatment of spatially oriented focal disease |
US4955365A (en) * | 1988-03-02 | 1990-09-11 | Laboratory Equipment, Corp. | Localization and therapy system for treatment of spatially oriented focal disease |
US5054470A (en) * | 1988-03-02 | 1991-10-08 | Laboratory Equipment, Corp. | Ultrasonic treatment transducer with pressurized acoustic coupling |
US4951653A (en) * | 1988-03-02 | 1990-08-28 | Laboratory Equipment, Corp. | Ultrasound brain lesioning system |
US4947046A (en) * | 1988-05-27 | 1990-08-07 | Konica Corporation | Method for preparation of radiographic image conversion panel and radiographic image conversion panel thereby |
US4938217A (en) * | 1988-06-21 | 1990-07-03 | Massachusetts Institute Of Technology | Electronically-controlled variable focus ultrasound hyperthermia system |
US4893624A (en) * | 1988-06-21 | 1990-01-16 | Massachusetts Institute Of Technology | Diffuse focus ultrasound hyperthermia system |
US4938216A (en) * | 1988-06-21 | 1990-07-03 | Massachusetts Institute Of Technology | Mechanically scanned line-focus ultrasound hyperthermia system |
US5265614A (en) * | 1988-08-30 | 1993-11-30 | Fujitsu Limited | Acoustic coupler |
US4976709A (en) * | 1988-12-15 | 1990-12-11 | Sand Bruce J | Method for collagen treatment |
US5123418A (en) * | 1989-02-28 | 1992-06-23 | Centre National De La Recherche Scientifique-C.N.R.S | Micro-echographic probe for ultrasound collimation through a deformable surface |
US5282797A (en) * | 1989-05-30 | 1994-02-01 | Cyrus Chess | Method for treating cutaneous vascular lesions |
US5435311A (en) * | 1989-06-27 | 1995-07-25 | Hitachi, Ltd. | Ultrasound therapeutic system |
US5115814A (en) * | 1989-08-18 | 1992-05-26 | Intertherapy, Inc. | Intravascular ultrasonic imaging probe and methods of using same |
US4973096A (en) * | 1989-08-21 | 1990-11-27 | Joyce Patrick H | Shoe transporting device |
US5158536A (en) * | 1989-08-28 | 1992-10-27 | Biopulmonics, Inc. | Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids |
US5156144A (en) * | 1989-10-20 | 1992-10-20 | Olympus Optical Co., Ltd. | Ultrasonic wave therapeutic device |
US5209720A (en) * | 1989-12-22 | 1993-05-11 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes |
US5012797A (en) * | 1990-01-08 | 1991-05-07 | Montefiore Hospital Association Of Western Pennsylvania | Method for removing skin wrinkles |
US5191880A (en) * | 1990-07-31 | 1993-03-09 | Mcleod Kenneth J | Method for the promotion of growth, ingrowth and healing of bone tissue and the prevention of osteopenia by mechanical loading of the bone tissue |
US5117832A (en) * | 1990-09-21 | 1992-06-02 | Diasonics, Inc. | Curved rectangular/elliptical transducer |
US5150714A (en) * | 1991-05-10 | 1992-09-29 | Sri International | Ultrasonic inspection method and apparatus with audible output |
US5224467A (en) * | 1991-10-30 | 1993-07-06 | Kabushiki Kaisha Machida Seisakusho | Endoscope with direction indication mechanism |
US5524620A (en) * | 1991-11-12 | 1996-06-11 | November Technologies Ltd. | Ablation of blood thrombi by means of acoustic energy |
US5230334A (en) * | 1992-01-22 | 1993-07-27 | Summit Technology, Inc. | Method and apparatus for generating localized hyperthermia |
US5269297A (en) * | 1992-02-27 | 1993-12-14 | Angiosonics Inc. | Ultrasonic transmission apparatus |
US5501655A (en) * | 1992-03-31 | 1996-03-26 | Massachusetts Institute Of Technology | Apparatus and method for acoustic heat generation and hyperthermia |
US5295484A (en) * | 1992-05-19 | 1994-03-22 | Arizona Board Of Regents For And On Behalf Of The University Of Arizona | Apparatus and method for intra-cardiac ablation of arrhythmias |
US5321520A (en) * | 1992-07-20 | 1994-06-14 | Automated Medical Access Corporation | Automated high definition/resolution image storage, retrieval and transmission system |
US5370121A (en) * | 1992-09-07 | 1994-12-06 | Siemens Aktiengesellschaft | Method and apparatus for non-invasive measurement of a temperature change in a subject |
US5360268A (en) * | 1992-11-02 | 1994-11-01 | Nippon Soken Inc. | Ultrasonic temperature measuring apparatus |
US5419327A (en) * | 1992-12-07 | 1995-05-30 | Siemens Aktiengesellschaft | Acoustic therapy means |
US5267985A (en) * | 1993-02-11 | 1993-12-07 | Trancell, Inc. | Drug delivery by multiple frequency phonophoresis |
US5460595A (en) * | 1993-06-01 | 1995-10-24 | Dynatronics Laser Corporation | Multi-frequency ultrasound therapy systems and methods |
US5526812A (en) * | 1993-06-21 | 1996-06-18 | General Electric Company | Display system for enhancing visualization of body structures during medical procedures |
US5503320A (en) * | 1993-08-19 | 1996-04-02 | United States Surgical Corporation | Surgical apparatus with indicator |
US5380280A (en) * | 1993-11-12 | 1995-01-10 | Peterson; Erik W. | Aspiration system having pressure-controlled and flow-controlled modes |
US5371483A (en) * | 1993-12-20 | 1994-12-06 | Bhardwaj; Mahesh C. | High intensity guided ultrasound source |
US5507790A (en) * | 1994-03-21 | 1996-04-16 | Weiss; William V. | Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism |
US5471488A (en) * | 1994-04-05 | 1995-11-28 | International Business Machines Corporation | Clock fault detection circuit |
US5492126A (en) * | 1994-05-02 | 1996-02-20 | Focal Surgery | Probe for medical imaging and therapy using ultrasound |
US5524624A (en) * | 1994-05-05 | 1996-06-11 | Amei Technologies Inc. | Apparatus and method for stimulating tissue growth with ultrasound |
US5458596A (en) * | 1994-05-06 | 1995-10-17 | Dorsal Orthopedic Corporation | Method and apparatus for controlled contraction of soft tissue |
US5522869A (en) * | 1994-05-17 | 1996-06-04 | Burdette; Everette C. | Ultrasound device for use in a thermotherapy apparatus |
US5496256A (en) * | 1994-06-09 | 1996-03-05 | Sonex International Corporation | Ultrasonic bone healing device for dental application |
US5487388A (en) * | 1994-11-01 | 1996-01-30 | Interspec. Inc. | Three dimensional ultrasonic scanning devices and techniques |
US5520188A (en) * | 1994-11-02 | 1996-05-28 | Focus Surgery Inc. | Annular array transducer |
US6623430B1 (en) * | 1997-10-14 | 2003-09-23 | Guided Therapy Systems, Inc. | Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system |
US6315741B1 (en) * | 1997-10-31 | 2001-11-13 | Roy W. Martin | Method and apparatus for medical procedures using high-intensity focused ultrasound |
US6413254B1 (en) * | 2000-01-19 | 2002-07-02 | Medtronic Xomed, Inc. | Method of tongue reduction by thermal ablation using high intensity focused ultrasound |
US20030176790A1 (en) * | 2000-12-28 | 2003-09-18 | Guided Therapy Systems, Inc. | Visual imaging system for ultrasonic probe |
US20040267252A1 (en) * | 2003-06-30 | 2004-12-30 | Ethicon, Inc. | Multi-modality ablation device |
US20050154332A1 (en) * | 2004-01-12 | 2005-07-14 | Onda | Methods and systems for removing hair using focused acoustic energy |
Cited By (212)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8853600B2 (en) | 1997-07-31 | 2014-10-07 | Miramar Labs, Inc. | Method and apparatus for treating subcutaneous histological features |
US8073550B1 (en) | 1997-07-31 | 2011-12-06 | Miramar Labs, Inc. | Method and apparatus for treating subcutaneous histological features |
US8480585B2 (en) | 1997-10-14 | 2013-07-09 | Guided Therapy Systems, Llc | Imaging, therapy and temperature monitoring ultrasonic system and method |
US9272162B2 (en) | 1997-10-14 | 2016-03-01 | Guided Therapy Systems, Llc | Imaging, therapy, and temperature monitoring ultrasonic method |
US9907535B2 (en) | 2000-12-28 | 2018-03-06 | Ardent Sound, Inc. | Visual imaging system for ultrasonic probe |
US8409097B2 (en) | 2000-12-28 | 2013-04-02 | Ardent Sound, Inc | Visual imaging system for ultrasonic probe |
US8235909B2 (en) | 2004-05-12 | 2012-08-07 | Guided Therapy Systems, L.L.C. | Method and system for controlled scanning, imaging and/or therapy |
US9114247B2 (en) | 2004-09-16 | 2015-08-25 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment with a multi-directional transducer |
US8708935B2 (en) | 2004-09-16 | 2014-04-29 | Guided Therapy Systems, Llc | System and method for variable depth ultrasound treatment |
US10039938B2 (en) | 2004-09-16 | 2018-08-07 | Guided Therapy Systems, Llc | System and method for variable depth ultrasound treatment |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
US7824348B2 (en) | 2004-09-16 | 2010-11-02 | Guided Therapy Systems, L.L.C. | System and method for variable depth ultrasound treatment |
US9095697B2 (en) | 2004-09-24 | 2015-08-04 | Guided Therapy Systems, Llc | Methods for preheating tissue for cosmetic treatment of the face and body |
US10328289B2 (en) | 2004-09-24 | 2019-06-25 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US11590370B2 (en) | 2004-09-24 | 2023-02-28 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US9895560B2 (en) | 2004-09-24 | 2018-02-20 | Guided Therapy Systems, Llc | Methods for rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US8672848B2 (en) | 2004-10-06 | 2014-03-18 | Guided Therapy Systems, Llc | Method and system for treating cellulite |
US10245450B2 (en) | 2004-10-06 | 2019-04-02 | Guided Therapy Systems, Llc | Ultrasound probe for fat and cellulite reduction |
US9283409B2 (en) | 2004-10-06 | 2016-03-15 | Guided Therapy Systems, Llc | Energy based fat reduction |
US11179580B2 (en) | 2004-10-06 | 2021-11-23 | Guided Therapy Systems, Llc | Energy based fat reduction |
US8066641B2 (en) | 2004-10-06 | 2011-11-29 | Guided Therapy Systems, L.L.C. | Method and system for treating photoaged tissue |
US8282554B2 (en) | 2004-10-06 | 2012-10-09 | Guided Therapy Systems, Llc | Methods for treatment of sweat glands |
US11167155B2 (en) | 2004-10-06 | 2021-11-09 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US8333700B1 (en) | 2004-10-06 | 2012-12-18 | Guided Therapy Systems, L.L.C. | Methods for treatment of hyperhidrosis |
US10960236B2 (en) | 2004-10-06 | 2021-03-30 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US10888718B2 (en) | 2004-10-06 | 2021-01-12 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US8366622B2 (en) | 2004-10-06 | 2013-02-05 | Guided Therapy Systems, Llc | Treatment of sub-dermal regions for cosmetic effects |
US10888716B2 (en) | 2004-10-06 | 2021-01-12 | Guided Therapy Systems, Llc | Energy based fat reduction |
US10888717B2 (en) | 2004-10-06 | 2021-01-12 | Guided Therapy Systems, Llc | Probe for ultrasound tissue treatment |
US9283410B2 (en) | 2004-10-06 | 2016-03-15 | Guided Therapy Systems, L.L.C. | System and method for fat and cellulite reduction |
US11207547B2 (en) | 2004-10-06 | 2021-12-28 | Guided Therapy Systems, Llc | Probe for ultrasound tissue treatment |
US10610705B2 (en) | 2004-10-06 | 2020-04-07 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US8460193B2 (en) | 2004-10-06 | 2013-06-11 | Guided Therapy Systems Llc | System and method for ultra-high frequency ultrasound treatment |
US10610706B2 (en) | 2004-10-06 | 2020-04-07 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US9320537B2 (en) | 2004-10-06 | 2016-04-26 | Guided Therapy Systems, Llc | Methods for noninvasive skin tightening |
US8506486B2 (en) | 2004-10-06 | 2013-08-13 | Guided Therapy Systems, Llc | Ultrasound treatment of sub-dermal tissue for cosmetic effects |
US8523775B2 (en) | 2004-10-06 | 2013-09-03 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US10603519B2 (en) | 2004-10-06 | 2020-03-31 | Guided Therapy Systems, Llc | Energy based fat reduction |
US10603523B2 (en) | 2004-10-06 | 2020-03-31 | Guided Therapy Systems, Llc | Ultrasound probe for tissue treatment |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US10532230B2 (en) | 2004-10-06 | 2020-01-14 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US10525288B2 (en) | 2004-10-06 | 2020-01-07 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US8636665B2 (en) | 2004-10-06 | 2014-01-28 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of fat |
US8641622B2 (en) | 2004-10-06 | 2014-02-04 | Guided Therapy Systems, Llc | Method and system for treating photoaged tissue |
US8663112B2 (en) | 2004-10-06 | 2014-03-04 | Guided Therapy Systems, Llc | Methods and systems for fat reduction and/or cellulite treatment |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US7758524B2 (en) | 2004-10-06 | 2010-07-20 | Guided Therapy Systems, L.L.C. | Method and system for ultra-high frequency ultrasound treatment |
US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
US8690778B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Energy-based tissue tightening |
US8690780B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive tissue tightening for cosmetic effects |
US11235180B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US10265550B2 (en) | 2004-10-06 | 2019-04-23 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US20060089632A1 (en) * | 2004-10-06 | 2006-04-27 | Guided Therapy Systems, L.L.C. | Method and system for treating acne and sebaceous glands |
US10252086B2 (en) | 2004-10-06 | 2019-04-09 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
US10238894B2 (en) | 2004-10-06 | 2019-03-26 | Guided Therapy Systems, L.L.C. | Energy based fat reduction |
US11338156B2 (en) | 2004-10-06 | 2022-05-24 | Guided Therapy Systems, Llc | Noninvasive tissue tightening system |
US10046181B2 (en) | 2004-10-06 | 2018-08-14 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US10046182B2 (en) | 2004-10-06 | 2018-08-14 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US9421029B2 (en) | 2004-10-06 | 2016-08-23 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US11400319B2 (en) | 2004-10-06 | 2022-08-02 | Guided Therapy Systems, Llc | Methods for lifting skin tissue |
US10010725B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, Llc | Ultrasound probe for fat and cellulite reduction |
US10010724B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US10010721B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, L.L.C. | Energy based fat reduction |
US8915853B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US8915854B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Method for fat and cellulite reduction |
US8915870B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Method and system for treating stretch marks |
US8920324B2 (en) | 2004-10-06 | 2014-12-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US10010726B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US8932224B2 (en) | 2004-10-06 | 2015-01-13 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US9974982B2 (en) | 2004-10-06 | 2018-05-22 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US11697033B2 (en) | 2004-10-06 | 2023-07-11 | Guided Therapy Systems, Llc | Methods for lifting skin tissue |
US7491171B2 (en) | 2004-10-06 | 2009-02-17 | Guided Therapy Systems, L.L.C. | Method and system for treating acne and sebaceous glands |
US9833639B2 (en) | 2004-10-06 | 2017-12-05 | Guided Therapy Systems, L.L.C. | Energy based fat reduction |
US9833640B2 (en) | 2004-10-06 | 2017-12-05 | Guided Therapy Systems, L.L.C. | Method and system for ultrasound treatment of skin |
US11717707B2 (en) | 2004-10-06 | 2023-08-08 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US9827450B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | System and method for fat and cellulite reduction |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US9713731B2 (en) | 2004-10-06 | 2017-07-25 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9707412B2 (en) | 2004-10-06 | 2017-07-18 | Guided Therapy Systems, Llc | System and method for fat and cellulite reduction |
US9039619B2 (en) | 2004-10-06 | 2015-05-26 | Guided Therapy Systems, L.L.C. | Methods for treating skin laxity |
US9700340B2 (en) | 2004-10-06 | 2017-07-11 | Guided Therapy Systems, Llc | System and method for ultra-high frequency ultrasound treatment |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US9694211B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US9533175B2 (en) | 2004-10-06 | 2017-01-03 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9427601B2 (en) | 2004-10-06 | 2016-08-30 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9522290B2 (en) | 2004-10-06 | 2016-12-20 | Guided Therapy Systems, Llc | System and method for fat and cellulite reduction |
US9440096B2 (en) | 2004-10-06 | 2016-09-13 | Guided Therapy Systems, Llc | Method and system for treating stretch marks |
US9427600B2 (en) | 2004-10-06 | 2016-08-30 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US8868958B2 (en) | 2005-04-25 | 2014-10-21 | Ardent Sound, Inc | Method and system for enhancing computer peripheral safety |
US8166332B2 (en) | 2005-04-25 | 2012-04-24 | Ardent Sound, Inc. | Treatment system for enhancing safety of computer peripheral for use with medical devices by isolating host AC power |
US20110201976A1 (en) * | 2005-06-01 | 2011-08-18 | Focus Surgery, Inc. | Laparoscopic hifu probe |
US8753339B2 (en) | 2005-09-07 | 2014-06-17 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9364246B2 (en) | 2005-09-07 | 2016-06-14 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9005229B2 (en) | 2005-09-07 | 2015-04-14 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US8574251B2 (en) | 2005-09-07 | 2013-11-05 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US9272124B2 (en) | 2005-12-02 | 2016-03-01 | Ulthera, Inc. | Systems and devices for selective cell lysis and methods of using same |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
US20080021353A1 (en) * | 2005-12-30 | 2008-01-24 | Manfred Menzi | Acoustic pressure wave applicator system with conduction pad |
US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
US20070213705A1 (en) * | 2006-03-08 | 2007-09-13 | Schmid Peter M | Insulated needle and system |
US9566454B2 (en) | 2006-09-18 | 2017-02-14 | Guided Therapy Systems, Llc | Method and sysem for non-ablative acne treatment and prevention |
US9241683B2 (en) | 2006-10-04 | 2016-01-26 | Ardent Sound Inc. | Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid |
US20080139974A1 (en) * | 2006-12-04 | 2008-06-12 | Da Silva Luiz B | Devices and Methods for Treatment of Skin Conditions |
US9492686B2 (en) * | 2006-12-04 | 2016-11-15 | Koninklijke Philips N.V. | Devices and methods for treatment of skin conditions |
US20100049178A1 (en) * | 2007-04-19 | 2010-02-25 | Deem Mark E | Methods and apparatus for reducing sweat production |
US10624696B2 (en) * | 2007-04-19 | 2020-04-21 | Miradry, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
US10166072B2 (en) | 2007-04-19 | 2019-01-01 | Miradry, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
US11419678B2 (en) | 2007-04-19 | 2022-08-23 | Miradry, Inc. | Methods, devices, and systems for non-invasive delivery of microwave therapy |
WO2008131302A3 (en) * | 2007-04-19 | 2009-12-30 | The Foundry, Inc. | Methods and apparatus for reducing sweat production |
US8401668B2 (en) | 2007-04-19 | 2013-03-19 | Miramar Labs, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
EP2532320A2 (en) | 2007-04-19 | 2012-12-12 | Miramar Labs, Inc. | Apparatus for reducing sweat production |
US10779887B2 (en) | 2007-04-19 | 2020-09-22 | Miradry, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
US8688228B2 (en) | 2007-04-19 | 2014-04-01 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US9241763B2 (en) | 2007-04-19 | 2016-01-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US9149331B2 (en) * | 2007-04-19 | 2015-10-06 | Miramar Labs, Inc. | Methods and apparatus for reducing sweat production |
US20170340384A1 (en) * | 2007-04-19 | 2017-11-30 | Mark E. Deem | Systems and methods for creating an effect using microwave energy to specified tissue |
US10463429B2 (en) | 2007-04-19 | 2019-11-05 | Miradry, Inc. | Methods, devices, and systems for non-invasive delivery of microwave therapy |
EP3391844A1 (en) | 2007-04-19 | 2018-10-24 | Miramar Labs, Inc. | Apparatus for reducing sweat production |
JP2010524591A (en) * | 2007-04-19 | 2010-07-22 | ザ ファウンドリー, インコーポレイテッド | Method and apparatus for reducing sweat production |
US9427285B2 (en) | 2007-04-19 | 2016-08-30 | Miramar Labs, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
JP2013176628A (en) * | 2007-04-19 | 2013-09-09 | Miramar Labs Inc | Method and apparatus for reducing sweat production |
US8764687B2 (en) | 2007-05-07 | 2014-07-01 | Guided Therapy Systems, Llc | Methods and systems for coupling and focusing acoustic energy using a coupler member |
US9216276B2 (en) | 2007-05-07 | 2015-12-22 | Guided Therapy Systems, Llc | Methods and systems for modulating medicants using acoustic energy |
US11717661B2 (en) | 2007-05-07 | 2023-08-08 | Guided Therapy Systems, Llc | Methods and systems for ultrasound assisted delivery of a medicant to tissue |
US20090062724A1 (en) * | 2007-08-31 | 2009-03-05 | Rixen Chen | System and apparatus for sonodynamic therapy |
US10220122B2 (en) | 2007-10-09 | 2019-03-05 | Ulthera, Inc. | System for tissue dissection and aspiration |
US9039722B2 (en) | 2007-10-09 | 2015-05-26 | Ulthera, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
US20090093737A1 (en) * | 2007-10-09 | 2009-04-09 | Cabochon Aesthetics, Inc. | Ultrasound apparatus with treatment lens |
US8825176B2 (en) | 2007-12-12 | 2014-09-02 | Miramar Labs, Inc. | Apparatus for the noninvasive treatment of tissue using microwave energy |
US8406894B2 (en) | 2007-12-12 | 2013-03-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
US11123039B2 (en) | 2008-06-06 | 2021-09-21 | Ulthera, Inc. | System and method for ultrasound treatment |
US11723622B2 (en) | 2008-06-06 | 2023-08-15 | Ulthera, Inc. | Systems for ultrasound treatment |
US10537304B2 (en) | 2008-06-06 | 2020-01-21 | Ulthera, Inc. | Hand wand for ultrasonic cosmetic treatment and imaging |
US20110196365A1 (en) * | 2008-10-22 | 2011-08-11 | Miramar Labs, Inc. | Systems, Apparatus, Methods, and Procedures for the Non-Invasive Treatment of Tissue Using Microwave Energy |
ITTR20080006A1 (en) * | 2008-12-17 | 2010-06-18 | Med Elettronica Srl | TRANSDUCER FOR LOCALIZED TREATMENTS BY MECHANICAL ULTRASOUND STRENGTH WITH COOLING SYSTEM WITH INTEGRATED SINK |
US20100222852A1 (en) * | 2009-02-24 | 2010-09-02 | Vasily David B | Apparatus and Method for Decolonizing Microbes on the Surfaces of the Skin and In Body Cavities |
US11337725B2 (en) | 2009-08-07 | 2022-05-24 | Ulthera, Inc. | Handpieces for tissue treatment |
US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
US8894678B2 (en) | 2009-08-07 | 2014-11-25 | Ulthera, Inc. | Cellulite treatment methods |
US8906054B2 (en) | 2009-08-07 | 2014-12-09 | Ulthera, Inc. | Apparatus for reducing the appearance of cellulite |
US8920452B2 (en) | 2009-08-07 | 2014-12-30 | Ulthera, Inc. | Methods of tissue release to reduce the appearance of cellulite |
US8979881B2 (en) | 2009-08-07 | 2015-03-17 | Ulthera, Inc. | Methods and handpiece for use in tissue dissection |
US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
US10531888B2 (en) | 2009-08-07 | 2020-01-14 | Ulthera, Inc. | Methods for efficiently reducing the appearance of cellulite |
US10485573B2 (en) | 2009-08-07 | 2019-11-26 | Ulthera, Inc. | Handpieces for tissue treatment |
US8900261B2 (en) | 2009-08-07 | 2014-12-02 | Ulthera, Inc. | Tissue treatment system for reducing the appearance of cellulite |
US9757145B2 (en) | 2009-08-07 | 2017-09-12 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9044259B2 (en) | 2009-08-07 | 2015-06-02 | Ulthera, Inc. | Methods for dissection of subcutaneous tissue |
US9078688B2 (en) | 2009-08-07 | 2015-07-14 | Ulthera, Inc. | Handpiece for use in tissue dissection |
US9510849B2 (en) | 2009-08-07 | 2016-12-06 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
US10271866B2 (en) | 2009-08-07 | 2019-04-30 | Ulthera, Inc. | Modular systems for treating tissue |
US8900262B2 (en) | 2009-08-07 | 2014-12-02 | Ulthera, Inc. | Device for dissection of subcutaneous tissue |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US9039617B2 (en) | 2009-11-24 | 2015-05-26 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US9345910B2 (en) | 2009-11-24 | 2016-05-24 | Guided Therapy Systems Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US10603066B2 (en) | 2010-05-25 | 2020-03-31 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US10183182B2 (en) | 2010-08-02 | 2019-01-22 | Guided Therapy Systems, Llc | Methods and systems for treating plantar fascia |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9149658B2 (en) | 2010-08-02 | 2015-10-06 | Guided Therapy Systems, Llc | Systems and methods for ultrasound treatment |
US20120165668A1 (en) * | 2010-08-02 | 2012-06-28 | Guided Therapy Systems, Llc | Systems and methods for treating acute and/or chronic injuries in soft tissue |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
US11213618B2 (en) | 2010-12-22 | 2022-01-04 | Ulthera, Inc. | System for tissue dissection and aspiration |
US8858471B2 (en) | 2011-07-10 | 2014-10-14 | Guided Therapy Systems, Llc | Methods and systems for ultrasound treatment |
US9452302B2 (en) | 2011-07-10 | 2016-09-27 | Guided Therapy Systems, Llc | Systems and methods for accelerating healing of implanted material and/or native tissue |
WO2013009785A2 (en) | 2011-07-10 | 2013-01-17 | Guided Therapy Systems, Llc. | Systems and methods for improving an outside appearance of skin using ultrasound as an energy source |
WO2013012641A1 (en) | 2011-07-11 | 2013-01-24 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9011337B2 (en) | 2011-07-11 | 2015-04-21 | Guided Therapy Systems, Llc | Systems and methods for monitoring and controlling ultrasound power output and stability |
US9028477B2 (en) | 2011-08-01 | 2015-05-12 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US9314301B2 (en) | 2011-08-01 | 2016-04-19 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US8469951B2 (en) | 2011-08-01 | 2013-06-25 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US8535302B2 (en) | 2011-08-01 | 2013-09-17 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US10321954B2 (en) | 2011-08-01 | 2019-06-18 | Miradry, Inc. | Applicator and tissue interface module for dermatological device |
US11123136B2 (en) | 2011-08-01 | 2021-09-21 | Miradry, Inc. | Applicator and tissue interface module for dermatological device |
US9268014B2 (en) | 2011-10-17 | 2016-02-23 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9247924B2 (en) | 2011-10-17 | 2016-02-02 | Butterfly Networks, Inc. | Transmissive imaging and related apparatus and methods |
US9022936B2 (en) | 2011-10-17 | 2015-05-05 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9198637B2 (en) | 2011-10-17 | 2015-12-01 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9028412B2 (en) | 2011-10-17 | 2015-05-12 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9149255B2 (en) | 2011-10-17 | 2015-10-06 | Butterfly Network, Inc. | Image-guided high intensity focused ultrasound and related apparatus and methods |
US8852103B2 (en) | 2011-10-17 | 2014-10-07 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9155521B2 (en) | 2011-10-17 | 2015-10-13 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9033884B2 (en) | 2011-10-17 | 2015-05-19 | Butterfly Network, Inc. | Transmissive imaging and related apparatus and methods |
US9268015B2 (en) | 2011-10-17 | 2016-02-23 | Butterfly Network, Inc. | Image-guided high intensity focused ultrasound and related apparatus and methods |
US20130123625A1 (en) * | 2011-11-14 | 2013-05-16 | Boston Scientific Scimed, Inc. | Integrated ultrasound ablation and imaging device and related methods |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
DE102012209008B4 (en) * | 2012-05-29 | 2015-02-05 | Wellcomet Gmbh | Apparatus for generating treatment waves |
DE102012209008A1 (en) * | 2012-05-29 | 2013-12-05 | Wellcomet Gmbh | Device for generation of e.g. radio frequency current for pressurization of human tissue with frequency current, has motion sensor cooperating with control unit such that intensity of wave is controlled depending on measurement signals |
US9802063B2 (en) | 2012-09-21 | 2017-10-31 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US10420960B2 (en) | 2013-03-08 | 2019-09-24 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
US11517772B2 (en) | 2013-03-08 | 2022-12-06 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
US10561862B2 (en) | 2013-03-15 | 2020-02-18 | Guided Therapy Systems, Llc | Ultrasound treatment device and methods of use |
US9667889B2 (en) | 2013-04-03 | 2017-05-30 | Butterfly Network, Inc. | Portable electronic devices with integrated imaging capabilities |
US10779885B2 (en) | 2013-07-24 | 2020-09-22 | Miradry. Inc. | Apparatus and methods for the treatment of tissue using microwave energy |
US11351401B2 (en) | 2014-04-18 | 2022-06-07 | Ulthera, Inc. | Band transducer ultrasound therapy |
US10603521B2 (en) | 2014-04-18 | 2020-03-31 | Ulthera, Inc. | Band transducer ultrasound therapy |
US20170080198A1 (en) * | 2015-09-22 | 2017-03-23 | Johnson & Johnson Consummer Inc. | Devices and methods for enhancing the topical application of a benefit agent |
US11224895B2 (en) | 2016-01-18 | 2022-01-18 | Ulthera, Inc. | Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board and method of assembly thereof |
US11241218B2 (en) | 2016-08-16 | 2022-02-08 | Ulthera, Inc. | Systems and methods for cosmetic ultrasound treatment of skin |
US20190009110A1 (en) * | 2017-07-06 | 2019-01-10 | Slender Medical Ltd. | Ultrasound energy applicator |
US11944849B2 (en) | 2018-02-20 | 2024-04-02 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
US11969609B2 (en) | 2022-12-05 | 2024-04-30 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
Also Published As
Publication number | Publication date |
---|---|
US8333700B1 (en) | 2012-12-18 |
US20150100075A1 (en) | 2015-04-09 |
US10960235B2 (en) | 2021-03-30 |
US20180333595A1 (en) | 2018-11-22 |
US20130310863A1 (en) | 2013-11-21 |
US8523775B2 (en) | 2013-09-03 |
US20160354618A1 (en) | 2016-12-08 |
US20120330222A1 (en) | 2012-12-27 |
US9421029B2 (en) | 2016-08-23 |
US20120330223A1 (en) | 2012-12-27 |
US8932224B2 (en) | 2015-01-13 |
US8282554B2 (en) | 2012-10-09 |
US20120197120A1 (en) | 2012-08-02 |
US10046181B2 (en) | 2018-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10960235B2 (en) | Energy based hyperhidrosis treatment | |
US11235179B2 (en) | Energy based skin gland treatment | |
US10888718B2 (en) | Ultrasound probe for treating skin laxity | |
US10252086B2 (en) | Ultrasound probe for treatment of skin | |
US9974982B2 (en) | System and method for noninvasive skin tightening | |
US7491171B2 (en) | Method and system for treating acne and sebaceous glands | |
US7615016B2 (en) | Method and system for treating stretch marks | |
US7530356B2 (en) | Method and system for noninvasive mastopexy | |
US11207548B2 (en) | Ultrasound probe for treating skin laxity | |
US20220023671A1 (en) | Ultrasound probe for treatment of skin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: GUIDED THERAPY SYSTEMS, L.L.C., ARIZONA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:MAKIN, INDER RAJ S.;BARTHE, PETER B.;SLAYTON, MICHAEL H.;REEL/FRAME:016952/0721;SIGNING DATES FROM 20051201 TO 20051216 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |