US20060024185A1 - Nasal sprays - Google Patents

Nasal sprays Download PDF

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Publication number
US20060024185A1
US20060024185A1 US10/526,455 US52645505A US2006024185A1 US 20060024185 A1 US20060024185 A1 US 20060024185A1 US 52645505 A US52645505 A US 52645505A US 2006024185 A1 US2006024185 A1 US 2006024185A1
Authority
US
United States
Prior art keywords
container
nasal spray
preparation
sesame oil
spray
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/526,455
Inventor
Åke Åkerman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PHARMACURE HEALTH CARE AB
Original Assignee
PHARMACURE HEALTH CARE AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31970241&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20060024185(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PHARMACURE HEALTH CARE AB filed Critical PHARMACURE HEALTH CARE AB
Assigned to PHARMACURE HEALTH CARE, AB reassignment PHARMACURE HEALTH CARE, AB ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: AKERMAN, AKE
Publication of US20060024185A1 publication Critical patent/US20060024185A1/en
Priority to US12/105,337 priority Critical patent/US20080220107A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B05B11/1016—Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element
    • B05B11/1018—Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element and the controlling element cooperating with means for opening or closing the inlet valve

Definitions

  • the present invention relates to nasal sprays, and in particular to nasal sprays of or including sesame oil.
  • preparations including sesame oil and in particular preparations comprising substantially pure sesame oil, can be used very successfully for the treatment of nasal discomfort, and in particular nasal dryness.
  • Such preparations have to date been administered by means of a hand operated applicator which sprays the preparation into the upper parts of the nasal cavity.
  • the spray includes a pump which is mounted by click fitted onto the top of a bottle containing the preparation.
  • Such a product is available commercially from the Applicant under the trade name Nozoil.
  • the invention seeks to overcome the above problem, so from a first aspect, the invention provides a nasal spray comprising a open mouthed container containing a preparation containing sesame oil, and preferably consisting of substantially pure sesame oil, and a spray pump dispenser mounted to close the open top of the container and having a dip tube extending down into the preparation, wherein the pump body is provided with a mounting collar which seals to the top of the container in an airtight manner.
  • the mounting collar is formed of a deformable material, for example aluminium which can be deformed around a flange provided around the mouth of the container to provide an airtight give an airtight closure.
  • a gasket is provided between the top of the container and the collar so as to ensure the seal.
  • top surface of the container around its mouth is provided with a raised annular rib which cooperates with the gasket to ensure a seal
  • the body parts of the pump may be made substantially of plastics materials and the mounting collar of the pump be configured so as to hold the pump components together.
  • the container is preferably made from coloured glass or plastics material.
  • FIG. 1 shows a partially exploded view of a spray according to the invention.
  • a spray dispenser 2 comprises a bottle 4 , a pump unit 6 , a pump actuator 8 and a cap (not shown) which fits over the pump actuator 8 .
  • a nasal preparation 10 is contained within the bottle 4 .
  • the preparation 10 in the preferred embodiment consists of substantially pure sesame oil.
  • the bottle 4 is made from a coloured glass so as to protect the sesame oil preparation 10 from light, and has a mouth 12 for receiving the pump unit 6 .
  • a mounting flange 14 for the pump unit 6 is provided around the mouth 12 .
  • the upper surface 16 of the flange is provided with a generally triangular sectioned rib 18 .
  • the pump unit 6 is of a type VP7 available commercially from Valois Division Pharmacie, and comprises a dip tube 20 which extends down into the preparation 10 within the bottle 4 , a main body 22 of plastics such as polypropylene, a valve 24 mounted within the body 22 a spring 26 and a stem.
  • the stem 28 has a lower bore portion 30 which receives the valve 24 , and a dispensing bore 32 extending therethrough.
  • the stem 28 and valve 24 are slidable within the body 22 , and a stop member 34 limits the upward movement of the stem 28 .
  • the body 20 and the stop 34 are held together by a deformable aluminium collar 36 .
  • a gasket 38 is provided between the upper flange 40 of the collar 36 and an opposing flange 42 of the stop member 34 .
  • the collar 36 also mounts the pump unit 6 on the bottle 4 .
  • the collar 36 also comprises a lower portion 44 which extends down and is deformed around the flange 14 of the bottle 4 .
  • a gasket 46 is positioned between the lower portion 44 of the collar 36 and the upper surface of the bottle flange 12 .
  • the annular rib 18 provided around the bottle mouth 12 engages with the gasket 46 to ensure an airtight joint between the collar 38 and the bottle 4 .
  • the actuator 8 comprises a body 48 which is received over the outer surface 50 of the pump unit 6 .
  • the body 48 is provided with an internal bore 52 having an enlarged lower end 54 which fits over and engages the upper end of the stem 30 .
  • the cap (not shown) will have suitable means for retaining the cap on the actuator 8 .
  • a user inserts the actuator 8 into a nostril and presses the actuator 8 and bottle 4 toward each other. This actuates the pump unit 6 to dispense a predetermined dose of the preparation 10 into the user's nostril.
  • the collar mounting arrangement disclosed reduces the seepage of air into the bottle 4 when the spray is not being used, thereby improving the shelf life of the preparation 10 .

Abstract

A nasal spray includes an open mouthed bottle containing a preparation containing sesame oil and a spray pump dispenser mounted to close the open top of the bottle. A dip tube extends down into the preparation. The pump body is provided with a mounting collar which seals to the top of the bottle in an airtight manner.

Description

  • The present invention relates to nasal sprays, and in particular to nasal sprays of or including sesame oil.
  • It has been found that preparations including sesame oil, and in particular preparations comprising substantially pure sesame oil, can be used very successfully for the treatment of nasal discomfort, and in particular nasal dryness.
  • Such preparations have to date been administered by means of a hand operated applicator which sprays the preparation into the upper parts of the nasal cavity. The spray includes a pump which is mounted by click fitted onto the top of a bottle containing the preparation. Such a product is available commercially from the Applicant under the trade name Nozoil.
  • It has been found, however, that over time sesame oil degrades with exposure to air. This means that the preparation may not have a particularly long shelf life. It will be appreciated that the spray may only be used occasionally, and ideally the product should have a shelf life of at least two years.
  • The applicant has recognised that one reason for the degradation in the shelf life of the product is the manner in which the applicator is fitted onto the bottle containing the preparation.
  • The present invention seeks to overcome the above problem, so from a first aspect, the invention provides a nasal spray comprising a open mouthed container containing a preparation containing sesame oil, and preferably consisting of substantially pure sesame oil, and a spray pump dispenser mounted to close the open top of the container and having a dip tube extending down into the preparation, wherein the pump body is provided with a mounting collar which seals to the top of the container in an airtight manner.
  • In this way, the admission of air to the contents of the container is limited when the spray is not being used, leading to an improved shelf life.
  • In the preferred embodiment, the mounting collar is formed of a deformable material, for example aluminium which can be deformed around a flange provided around the mouth of the container to provide an airtight give an airtight closure.
  • Preferably a gasket is provided between the top of the container and the collar so as to ensure the seal.
  • Most preferably the top surface of the container around its mouth is provided with a raised annular rib which cooperates with the gasket to ensure a seal
  • The body parts of the pump may be made substantially of plastics materials and the mounting collar of the pump be configured so as to hold the pump components together.
  • In order to reduce damage to the container contents due to light, the container is preferably made from coloured glass or plastics material.
  • A preferred embodiment of the invention will now be described with reference to the accompanied drawings in which to FIG. 1 shows a partially exploded view of a spray according to the invention.
  • With reference to FIG. 1, a spray dispenser 2 comprises a bottle 4, a pump unit 6, a pump actuator 8 and a cap (not shown) which fits over the pump actuator 8. A nasal preparation 10 is contained within the bottle 4. The preparation 10 in the preferred embodiment consists of substantially pure sesame oil.
  • The bottle 4 is made from a coloured glass so as to protect the sesame oil preparation 10 from light, and has a mouth 12 for receiving the pump unit 6. A mounting flange 14 for the pump unit 6 is provided around the mouth 12. The upper surface 16 of the flange is provided with a generally triangular sectioned rib 18.
  • The pump unit 6 is of a type VP7 available commercially from Valois Division Pharmacie, and comprises a dip tube 20 which extends down into the preparation 10 within the bottle 4, a main body 22 of plastics such as polypropylene, a valve 24 mounted within the body 22 a spring 26 and a stem. The stem 28 has a lower bore portion 30 which receives the valve 24, and a dispensing bore 32 extending therethrough. The stem 28 and valve 24 are slidable within the body 22, and a stop member 34 limits the upward movement of the stem 28.
  • The body 20 and the stop 34 are held together by a deformable aluminium collar 36. A gasket 38 is provided between the upper flange 40 of the collar 36 and an opposing flange 42 of the stop member 34.
  • The collar 36 also mounts the pump unit 6 on the bottle 4. To this end, the collar 36 also comprises a lower portion 44 which extends down and is deformed around the flange 14 of the bottle 4. A gasket 46 is positioned between the lower portion 44 of the collar 36 and the upper surface of the bottle flange 12. The annular rib 18 provided around the bottle mouth 12 engages with the gasket 46 to ensure an airtight joint between the collar 38 and the bottle 4.
  • The actuator 8 comprises a body 48 which is received over the outer surface 50 of the pump unit 6. The body 48 is provided with an internal bore 52 having an enlarged lower end 54 which fits over and engages the upper end of the stem 30.
  • The cap (not shown) will have suitable means for retaining the cap on the actuator 8.
  • To use the spray, a user inserts the actuator 8 into a nostril and presses the actuator 8 and bottle 4 toward each other. This actuates the pump unit 6 to dispense a predetermined dose of the preparation 10 into the user's nostril.
  • It will be appreciated that the collar mounting arrangement disclosed reduces the seepage of air into the bottle 4 when the spray is not being used, thereby improving the shelf life of the preparation 10.

Claims (8)

1. A nasal spray comprising a open mouthed container containing a preparation containing sesame oil and a spray pump dispenser mounted to close the open top of the container and having a dip tube extending down into the preparation, wherein the pump body is provided with a mounting collar which seals to the top of the container in an airtight manner.
2. A nasal spray as claimed in claim 1 wherein the preparation containing sesame oil consists of substantially pure sesame oil.
3. A nasal spray as claimed in claim 1 wherein the mounting collar is formed of a deformable material which is deformed around a flange around the mouth of the container.
4. A nasal spray as claimed in claim 3, wherein the deformable material is aluminum.
5. A nasal spray as claimed in claim 3 wherein a gasket is provided between the top of the container and the collar.
6. A nasal spray as claimed in claim 5 wherein the surface of the container around its mouth is provided with a raised annular rib which cooperates with the gasket.
7. A nasal spray as claimed in claim 1 wherein the body parts of the pump are held together by the mounting collar.
8. A nasal spray as claimed in claim 1 wherein the container is made from a colored glass or plastics material.
US10/526,455 2002-09-03 2002-09-03 Nasal sprays Abandoned US20060024185A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/105,337 US20080220107A1 (en) 2002-09-03 2008-04-18 Nasal spray apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2002/009810 WO2004022141A1 (en) 2002-09-03 2002-09-03 Nasal sprays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/105,337 Continuation-In-Part US20080220107A1 (en) 2002-09-03 2008-04-18 Nasal spray apparatus

Publications (1)

Publication Number Publication Date
US20060024185A1 true US20060024185A1 (en) 2006-02-02

Family

ID=31970241

Family Applications (1)

Application Number Title Priority Date Filing Date
US10/526,455 Abandoned US20060024185A1 (en) 2002-09-03 2002-09-03 Nasal sprays

Country Status (7)

Country Link
US (1) US20060024185A1 (en)
EP (1) EP1539285B2 (en)
AT (1) ATE401105T1 (en)
AU (1) AU2002333785A1 (en)
DE (1) DE60227712D1 (en)
DK (1) DK1539285T4 (en)
WO (1) WO2004022141A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
US20170151258A1 (en) * 2011-03-31 2017-06-01 Acorda Therapeutics, Inc. Intranasal benzodiazepine pharmaceutical compositions
US10071211B2 (en) 2011-01-31 2018-09-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
USD995753S1 (en) * 2021-02-16 2023-08-15 Joanne M. Tobiasz-Dey Nasal spray device
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices

Citations (32)

* Cited by examiner, † Cited by third party
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US244095A (en) * 1881-07-12 Razor-strop
US3583605A (en) * 1969-01-17 1971-06-08 Diamond Int Corp Liquid dispensing pump
US3702669A (en) * 1970-02-05 1972-11-14 Ronald F Ewald Aerosol container
US4121731A (en) * 1977-05-23 1978-10-24 Scott Okerstrum Top enclosure for children's drinking vessels
US4735347A (en) * 1985-05-28 1988-04-05 Emson Research, Inc. Single puff atomizing pump dispenser
US4858790A (en) * 1987-09-07 1989-08-22 Bespak Plc Collapsible chamber metering valve
US4946069A (en) * 1987-10-10 1990-08-07 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for manually discharging flowable media
US5069369A (en) * 1990-02-27 1991-12-03 Risdon Corporation Method and assembly for retaining a mounting cup with a sealing collar
US5108013A (en) * 1984-04-16 1992-04-28 Risdon Corporation Pump for dispensing liquid from a container
US5232687A (en) * 1990-08-29 1993-08-03 Ursapharm Arzneimittel Gmbh Fluid dispenser for germ-free fluid
US5335823A (en) * 1990-08-31 1994-08-09 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for media
US5514365A (en) * 1988-10-11 1996-05-07 Schiapparelli Salute S.P.A. Pharmaceutical compositions comprising calcitonin for intranasal administration
US5692649A (en) * 1994-01-14 1997-12-02 Ursatec Verpackung Gmbh Suction and force pump for a container providing for the removal of residual air after filling
US5769274A (en) * 1994-04-08 1998-06-23 Sofab Pump dispenser for a container with a flexible bag
US5976673A (en) * 1996-02-15 1999-11-02 Canon Kabushiki Kaisha Ink-jet printing cloth, ink-jet printing process and print
US5983084A (en) * 1997-06-06 1999-11-09 Trw Inc. Transmitter having an improved LC oscillator
US6053368A (en) * 1995-11-17 2000-04-25 Ursatec Verpackung-Gmbh Anti-contamination dispensing apparatus for fluids
US6059150A (en) * 1997-06-03 2000-05-09 Ing. Erich Pfeiffer Gmbh Media dispenser having a plurality of flow operating states
US6062430A (en) * 1993-05-05 2000-05-16 Ing. Erich Pfeiffer Gmbh Dispensing container with variable volume compensation
US6135358A (en) * 1997-10-17 2000-10-24 Mefar S.P.A. Apparatus for washing the nasal cavities
US6156792A (en) * 1996-10-01 2000-12-05 Smithkline Beecham Corporation Calcium mupirocin non-aqueous nasal spray for otitis media or for recurrent acute bacterial sinusitis
US6296882B1 (en) * 2000-06-12 2001-10-02 Manuel Viamonte, Jr. Non-toxic mucosal disinfectant containing isopropyl alcohol, sesame oil, and lemon oil
US20020074429A1 (en) * 2000-10-28 2002-06-20 Patrick Hettrich Atomiser for fluids
US6427680B1 (en) * 1997-06-18 2002-08-06 Valois S.A. Nasal applicator and a dispenser device including such an applicator
US6427876B1 (en) * 1998-10-06 2002-08-06 Ing. Erich Pfeiffer Gmbh Media dispenser with integrally formed, separable and complementary nozzle parts
US20020104853A1 (en) * 1997-06-13 2002-08-08 Valois S.A. Fluid product dispenser with snap-on fixing ring
US6454185B2 (en) * 2000-02-12 2002-09-24 Ing. Erich Pfeiffer Gmbh Discharge apparatus for media
US6528081B1 (en) * 1997-07-22 2003-03-04 Gerhard Zellner Nasal spray liquid
US6824020B1 (en) * 1999-06-10 2004-11-30 Valois S.A. Dispensing head and fluid product dispensing device comprising same
US6851583B2 (en) * 2002-07-13 2005-02-08 Aero Pump Gmbh Double-acting pump for ejecting a product from a container
US7021503B2 (en) * 2001-04-04 2006-04-04 Valois S.A.S. Metal crimping cap for a fluid dispensing device
US7040511B1 (en) * 1999-09-09 2006-05-09 Valois S.A. Pump for dispensing fluid product, and fluid product dispensing device comprising same

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA758010B (en) * 1975-11-14 1977-08-31 Syntex Inc Nasal spray adapter
IL91856A0 (en) * 1988-10-11 1990-06-10 Schiapparelli Salute Spa Pharmaceutical compositions comprising calcitonin for intranasal administration and a spray unit for the administration of the same
GB2372782B (en) * 2000-09-29 2004-09-22 Pharmacure Ab Nasal sprays
DE10064950A1 (en) † 2000-12-23 2002-07-11 Impetus Ag Basel Thixotropic nasal spray

Patent Citations (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US244095A (en) * 1881-07-12 Razor-strop
US3583605A (en) * 1969-01-17 1971-06-08 Diamond Int Corp Liquid dispensing pump
US3702669A (en) * 1970-02-05 1972-11-14 Ronald F Ewald Aerosol container
US4121731A (en) * 1977-05-23 1978-10-24 Scott Okerstrum Top enclosure for children's drinking vessels
US5108013A (en) * 1984-04-16 1992-04-28 Risdon Corporation Pump for dispensing liquid from a container
US4735347A (en) * 1985-05-28 1988-04-05 Emson Research, Inc. Single puff atomizing pump dispenser
US4858790A (en) * 1987-09-07 1989-08-22 Bespak Plc Collapsible chamber metering valve
US4946069A (en) * 1987-10-10 1990-08-07 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for manually discharging flowable media
US5514365A (en) * 1988-10-11 1996-05-07 Schiapparelli Salute S.P.A. Pharmaceutical compositions comprising calcitonin for intranasal administration
US5069369A (en) * 1990-02-27 1991-12-03 Risdon Corporation Method and assembly for retaining a mounting cup with a sealing collar
US5232687A (en) * 1990-08-29 1993-08-03 Ursapharm Arzneimittel Gmbh Fluid dispenser for germ-free fluid
US5335823A (en) * 1990-08-31 1994-08-09 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for media
US6062430A (en) * 1993-05-05 2000-05-16 Ing. Erich Pfeiffer Gmbh Dispensing container with variable volume compensation
US5692649A (en) * 1994-01-14 1997-12-02 Ursatec Verpackung Gmbh Suction and force pump for a container providing for the removal of residual air after filling
US5769274A (en) * 1994-04-08 1998-06-23 Sofab Pump dispenser for a container with a flexible bag
US6053368A (en) * 1995-11-17 2000-04-25 Ursatec Verpackung-Gmbh Anti-contamination dispensing apparatus for fluids
US5976673A (en) * 1996-02-15 1999-11-02 Canon Kabushiki Kaisha Ink-jet printing cloth, ink-jet printing process and print
US6156792A (en) * 1996-10-01 2000-12-05 Smithkline Beecham Corporation Calcium mupirocin non-aqueous nasal spray for otitis media or for recurrent acute bacterial sinusitis
US6059150A (en) * 1997-06-03 2000-05-09 Ing. Erich Pfeiffer Gmbh Media dispenser having a plurality of flow operating states
US5983084A (en) * 1997-06-06 1999-11-09 Trw Inc. Transmitter having an improved LC oscillator
US20020104853A1 (en) * 1997-06-13 2002-08-08 Valois S.A. Fluid product dispenser with snap-on fixing ring
US6427680B1 (en) * 1997-06-18 2002-08-06 Valois S.A. Nasal applicator and a dispenser device including such an applicator
US6528081B1 (en) * 1997-07-22 2003-03-04 Gerhard Zellner Nasal spray liquid
US6135358A (en) * 1997-10-17 2000-10-24 Mefar S.P.A. Apparatus for washing the nasal cavities
US6427876B1 (en) * 1998-10-06 2002-08-06 Ing. Erich Pfeiffer Gmbh Media dispenser with integrally formed, separable and complementary nozzle parts
US6824020B1 (en) * 1999-06-10 2004-11-30 Valois S.A. Dispensing head and fluid product dispensing device comprising same
US7040511B1 (en) * 1999-09-09 2006-05-09 Valois S.A. Pump for dispensing fluid product, and fluid product dispensing device comprising same
US6454185B2 (en) * 2000-02-12 2002-09-24 Ing. Erich Pfeiffer Gmbh Discharge apparatus for media
US6296882B1 (en) * 2000-06-12 2001-10-02 Manuel Viamonte, Jr. Non-toxic mucosal disinfectant containing isopropyl alcohol, sesame oil, and lemon oil
US20020074429A1 (en) * 2000-10-28 2002-06-20 Patrick Hettrich Atomiser for fluids
US7021503B2 (en) * 2001-04-04 2006-04-04 Valois S.A.S. Metal crimping cap for a fluid dispensing device
US6851583B2 (en) * 2002-07-13 2005-02-08 Aero Pump Gmbh Double-acting pump for ejecting a product from a container

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
US10071211B2 (en) 2011-01-31 2018-09-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
US20170151258A1 (en) * 2011-03-31 2017-06-01 Acorda Therapeutics, Inc. Intranasal benzodiazepine pharmaceutical compositions
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
USD995753S1 (en) * 2021-02-16 2023-08-15 Joanne M. Tobiasz-Dey Nasal spray device

Also Published As

Publication number Publication date
AU2002333785A1 (en) 2004-03-29
DK1539285T3 (en) 2008-11-10
EP1539285B2 (en) 2011-10-12
DE60227712D1 (en) 2008-08-28
WO2004022141A1 (en) 2004-03-18
EP1539285B1 (en) 2008-07-16
EP1539285A1 (en) 2005-06-15
ATE401105T1 (en) 2008-08-15
DK1539285T4 (en) 2012-01-02

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Legal Events

Date Code Title Description
AS Assignment

Owner name: PHARMACURE HEALTH CARE, AB, SWEDEN

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:AKERMAN, AKE;REEL/FRAME:016677/0508

Effective date: 20050502

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION