US20050039749A1 - Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase - Google Patents

Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase Download PDF

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US20050039749A1
US20050039749A1 US10/657,405 US65740503A US2005039749A1 US 20050039749 A1 US20050039749 A1 US 20050039749A1 US 65740503 A US65740503 A US 65740503A US 2005039749 A1 US2005039749 A1 US 2005039749A1
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port
patient
inhalation
conduit
exsufflation
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US6860265B1 (en
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George Emerson
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Respironics Inc
Philips RS North America LLC
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Assigned to J.H. EMERSON COMPANY reassignment J.H. EMERSON COMPANY CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE'S NAME, PREVIOUSLY RECORDED AT REEL 014488 FRAME 0332. Assignors: EMERSON, GEORGE P.
Priority to AT04782919T priority patent/ATE539787T1/en
Priority to PCT/US2004/028522 priority patent/WO2005025477A2/en
Priority to AU2004271999A priority patent/AU2004271999B2/en
Priority to CNB200480025702XA priority patent/CN100512899C/en
Priority to JP2006525428A priority patent/JP4617308B2/en
Priority to EP04782919A priority patent/EP1663361B1/en
Priority to CA2537353A priority patent/CA2537353C/en
Publication of US20050039749A1 publication Critical patent/US20050039749A1/en
Publication of US6860265B1 publication Critical patent/US6860265B1/en
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Priority to IL174058A priority patent/IL174058A/en
Assigned to RESPIRONICS, INC. reassignment RESPIRONICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: J.H. EMERSON COMPANY
Assigned to RIC INVESTMENTS, INC. reassignment RIC INVESTMENTS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: RESPIRONICS, INC.
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Assigned to PHILIPS RS NORTH AMERICA LLC reassignment PHILIPS RS NORTH AMERICA LLC CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: RESPIRONICS, INC.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A61M16/202—Controlled valves electrically actuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M16/0006—Accessories therefor, e.g. sensors, vibrators, negative pressure with means for creating vibrations in patients' airways
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M16/0009—Accessories therefor, e.g. sensors, vibrators, negative pressure with sub-atmospheric pressure, e.g. during expiration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0066—Blowers or centrifugal pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A61M16/0841—Joints or connectors for sampling
    • A61M16/0858—Pressure sampling ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/1055—Filters bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0024—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter

Definitions

  • This invention relates to an improved insufflation-exsufflation system with automatic triggering of inhalation phase.
  • MI-E mechanical insufflation and exsufflation
  • SMA spinal muscular atrophy
  • ALS amyotropic lateral sclerosis
  • the technique involves the use of a blower and valve, which, via a facemask, mouthpiece or adapter for a tracheal tube, alternately applies positive pressure first to inflate the lungs, then shifts rapidly to negative pressure to create a high expiratory flow.
  • the internal valve executes a sequence of pressures applied to the patient's airway: first positive pressure to inflate the lungs, then a shift to negative pressure to create a high exhalation flow.
  • This sequence is typically repeated a number of times (anywhere from 2 to 6 ) in succession for a treatment.
  • the timing of each phase is adjustable by the user. Also, the initiation of the sequence is begun by the user actuating a switch. Alternatively, the user may also initiate each phase by actuating a switch while in a manual mode.
  • MI-E devices One shortcoming of current MI-E devices is that the beginning of an inhalation phase (positive pressure to first inflate the lungs) is triggered by either the patient or the patient's caregiver actuating a switch to begin the cycling. If the sequence is begun while the patient is exhaling, or the patient is not ready for an inhalation from the device, the patient may find the first inhalation uncomfortable, and may even unconsciously block the flow of air into the lungs. This can limit the effectiveness of the treatment, since a full deep inhalation breath is necessary to achieve adequate exhalation flow. Typically a caregiver must “coach” the patient during a treatment, explaining when to inhale, to avoid this problem.
  • the caregiver watches the patient's respiration in order to switch on the cycling when the patient begins to inhale.
  • Another shortcoming of the current device is that it is difficult to use on very young pediatric patients, and on unconscious or uncooperative patients, where it is difficult to explain to the patient when to begin an inhalation.
  • Assist modes have been used on positive pressure ventilators, which “breathe” a patient by applying a positive pressure to the airway, usually via an endotracheal or tracheostomy tube. Such assist modes also detect the patient's inspiratory effort in order to trigger the delivery of a breath by the ventilator. More recently, the advent of bi-level Continuous Positive Airway Pressure (CPAP) devices to support patients with respiratory insufficiency has also resulted in the use of some means to detect when the patient has begun inhalation, in order to determine when to increase the pressure applied to the airway.
  • CPAP Continuous Positive Airway Pressure
  • the invention results from the realization that an improved insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase can be effected by selectively connecting a patients breathing conduit to a positive pressure port, a negative pressure port and a dwell port, only after an inhalation of the patient has been sensed while the conduit is connected to the dwell port.
  • This invention features an improved insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of the inhalation phase.
  • a conduit for connection to a patient's airway and a pressure source with a positive pressure port and negative pressure port.
  • a switching device selectively connects the conduit to the positive pressure port, the negative pressure port and a dwell port.
  • a sensor system senses an inhalation by the patient.
  • a controller system drives the switching device to connect the conduit sequentially to the positive port, the negative port and the dwell port and to return again to the positive port in response to the sensor system sensing an inhalation by the patient while the conduit is connected to the dwell port.
  • the switching device may include a selector valve or valves and an actuator device.
  • the sensor system may include a pressure sensor in the conduit or an airflow detector.
  • the controller system may include a programmed timer.
  • FIG. 1 is a schematic block diagram of an insufflation-exsufflation system according to this invention.
  • FIGS. 2 and 3 are schematic diagrams showing alternative connections of the system to a patient's airway.
  • FIG. 4 shows an alternative embodiment of a sensor system employing a flow sensor
  • FIG. 5 is a more detailed schematic diagram of the positive/negative pressure source of FIG. 1 ;
  • FIG. 6 is a schematic diagram showing in more detail the program timer of FIG. 5 .
  • FIG. 1 An improved insufflation-exsufflation system 10 according to this invention, including a positive/negative pressure source 12 and a conduit 14 through which it provides the positive and negative pressure to patient 16 through, for example, a face mask 18 .
  • conduit 14 FIG. 2
  • a bacterial filter 24 may be employed in various location in conduit 14 .
  • a pressure transducer or pressure switch 26 may be employed to sense the pressure in conduit 14 .
  • pressure transducer or pressure switch 26 may be replaced by a flow sensor 26 a , FIG. 4 , or any other suitable device which can sense the beginning of an inhalation by patient 16 , for example, electrodes, strain gauges, or chest strap devices may be put on or around the patient's body or chest cavity to sense the beginning of an inhalation independent of the actual airflow characteristics in the airway of the patient.
  • Pressure source 12 may include a conventional blower 30 which provides a positive pressure during the inhale cycle in line 32 at positive pressure port 34 and a negative pressure during exhale in line 36 at negative pressure port 38 .
  • Dwell port 40 is provided for connection to ambient or atmospheric pressure, and may also include a flow restrictor 41 to make the sensor 26 more sensitive when it is, for example, a pressure sensor or pressure switch.
  • Programmed timer 42 drives actuator device or actuator motor 44 which through eccentric drive 46 moves swinger 48 of slider valve 50 from positive port 34 to negative port 38 , then to dwell port 40 .
  • Swinger 48 remains there until sensor 26 senses that a patient inhalation has begun, at which point it sends a signal on line 28 to program timer 42 to once again operate actuator motor 44 to move slider switch 50 through the cycle of positive port 34 , negative port 38 and dwell port 40 .
  • Programmed timer 42 may include a timer 60 , FIG. 6 , which operates driver circuit 62 that causes actuator motor 44 to step through the three positions of swinger 48 : positive port 34 , negative port 38 , and dwell port 40 .
  • An alternate output 59 of the timer 60 indicates when the driver 62 is holding the swinger 48 at the dwell port 40 , and provides one input to AND gate 66 .
  • pressure sensor 26 senses that a patient inhalation is beginning it also provides an input to AND gate 66 .
  • both those inputs are present at AND gate 66 it provides an output on line 28 to timer 60 to start the cycle again beginning with connection of swinger 48 to positive port 34 .

Abstract

An improved insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase includes a conduit for connection to a patient's airway; a pressure source with a positive pressure port and a negative pressure port; a switching device selectively connecting the conduit to the positive pressure port, the negative pressure port and the dwell port; the sensor system for sensing an inhalation by the patient; and a controller system for driving the switching device to connect the conduits sequentially to the positive port, the negative port and the dwell port and to return again to the positive port in response to the sensor system sensing an inhalation by the patient while the conduit is connected to the dwell port.

Description

    FIELD OF THE INVENTION
  • This invention relates to an improved insufflation-exsufflation system with automatic triggering of inhalation phase.
    • BACKGROUND OF THE INVENTION
  • The use of mechanical insufflation and exsufflation (MI-E) with negative pressure is a well-known technique for helping patients with an ineffective cough to remove secretions from the respiratory tract. Patients who can benefit from the technique include: post-polio, muscular dystrophy, spinal muscular atrophy (SMA), post-cardiac surgery, amyotropic lateral sclerosis (ALS), mechanically ventilated, or anyone with insufficient muscle strength to generate the high expiratory flows necessary for moving secretions up the tracheo-bronchial tree. The technique involves the use of a blower and valve, which, via a facemask, mouthpiece or adapter for a tracheal tube, alternately applies positive pressure first to inflate the lungs, then shifts rapidly to negative pressure to create a high expiratory flow.
  • During automatic operation of the device, the internal valve executes a sequence of pressures applied to the patient's airway: first positive pressure to inflate the lungs, then a shift to negative pressure to create a high exhalation flow. This sequence is typically repeated a number of times (anywhere from 2 to 6) in succession for a treatment. The timing of each phase is adjustable by the user. Also, the initiation of the sequence is begun by the user actuating a switch. Alternatively, the user may also initiate each phase by actuating a switch while in a manual mode.
  • One shortcoming of current MI-E devices is that the beginning of an inhalation phase (positive pressure to first inflate the lungs) is triggered by either the patient or the patient's caregiver actuating a switch to begin the cycling. If the sequence is begun while the patient is exhaling, or the patient is not ready for an inhalation from the device, the patient may find the first inhalation uncomfortable, and may even unconsciously block the flow of air into the lungs. This can limit the effectiveness of the treatment, since a full deep inhalation breath is necessary to achieve adequate exhalation flow. Typically a caregiver must “coach” the patient during a treatment, explaining when to inhale, to avoid this problem. Alternatively, the caregiver watches the patient's respiration in order to switch on the cycling when the patient begins to inhale. Another shortcoming of the current device is that it is difficult to use on very young pediatric patients, and on unconscious or uncooperative patients, where it is difficult to explain to the patient when to begin an inhalation.
  • Assist modes have been used on positive pressure ventilators, which “breathe” a patient by applying a positive pressure to the airway, usually via an endotracheal or tracheostomy tube. Such assist modes also detect the patient's inspiratory effort in order to trigger the delivery of a breath by the ventilator. More recently, the advent of bi-level Continuous Positive Airway Pressure (CPAP) devices to support patients with respiratory insufficiency has also resulted in the use of some means to detect when the patient has begun inhalation, in order to determine when to increase the pressure applied to the airway.
  • While automatic assist modes work well with positive pressure ventilators they are not easily applicable to insufflation-exsufflation systems. In positive pressure ventilators the slight negative pressure or flow created by a patient inhalation is used to trigger a delivery of positive pressure, the breath or inhalation, for the patient. Then the positive pressure is stopped as the patient exhales to atmospheric or slight positive pressure. Following this the next negative pressure or flow sensed when the patient again inhales can be used to trigger delivery of the next positive pressure. In contrast in insufflation-exsufflation systems after the inhale/positive pressure comes the exhale negative pressure. After the time set for the negative pressure the system will return to the positive pressure but on the basis of the existing negative pressure which may not be the negative pressure created by a patient inhalation, thereby losing synchronism with the normal breathing of the patient.
    • BRIEF SUMMARY OF THE INVENTION
  • It is therefore an object of this invention to provide an improved insufflation-exsufflation system for removal of broncho-pulmonary secretions.
  • It is a further object of this invention to provide such an improved insufflation-exsufflation system with reliable automatic triggering of the inhalation phase.
  • It is a further object of this invention to provide such an improved insufflation-exsufflation system, which is easier to synchronize with a patient's spontaneous breaths.
  • It is a further object of this invention to provide such an improved insufflation-exsufflation system, which increases inhalation volume for patients including unconscious, uncooperative, and pediatric patients.
  • It is a further object of this invention to provide such an improved insufflation-exsufflation system which is more comfortable for patients.
  • The invention results from the realization that an improved insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase can be effected by selectively connecting a patients breathing conduit to a positive pressure port, a negative pressure port and a dwell port, only after an inhalation of the patient has been sensed while the conduit is connected to the dwell port.
  • This invention features an improved insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of the inhalation phase. There is a conduit for connection to a patient's airway and a pressure source with a positive pressure port and negative pressure port. A switching device selectively connects the conduit to the positive pressure port, the negative pressure port and a dwell port. A sensor system senses an inhalation by the patient. A controller system drives the switching device to connect the conduit sequentially to the positive port, the negative port and the dwell port and to return again to the positive port in response to the sensor system sensing an inhalation by the patient while the conduit is connected to the dwell port.
  • In a preferred embodiment the switching device may include a selector valve or valves and an actuator device. The sensor system may include a pressure sensor in the conduit or an airflow detector. The controller system may include a programmed timer.
    • BRIEF DESCRIPTION OF THE DRAWINGS
  • Other objects, features and advantages will occur to those skilled in the art from the following description of a preferred embodiment and the accompanying drawings, in which:
  • FIG. 1 is a schematic block diagram of an insufflation-exsufflation system according to this invention.
  • FIGS. 2 and 3 are schematic diagrams showing alternative connections of the system to a patient's airway.
  • FIG. 4 shows an alternative embodiment of a sensor system employing a flow sensor,
  • FIG. 5 is a more detailed schematic diagram of the positive/negative pressure source of FIG. 1; and
  • FIG. 6 is a schematic diagram showing in more detail the program timer of FIG. 5.
    • DISCLOSURE OF THE PREFERRED EMBODIMENT
  • Aside from the preferred embodiment or embodiments disclosed below, this invention is capable of other embodiments and of being practiced or being carried out in various ways. Thus, it is to be understood that the invention is not limited in its application to the details of construction and the arrangements of components set forth in the following description or illustrated in the drawings.
  • There is shown in FIG. 1 an improved insufflation-exsufflation system 10 according to this invention, including a positive/negative pressure source 12 and a conduit 14 through which it provides the positive and negative pressure to patient 16 through, for example, a face mask 18. Alternatively, conduit 14, FIG. 2, may be connected directly to a tracheostomy tube 20 or as shown in FIG. 3, to an endotracheal tube 22. A bacterial filter 24 may be employed in various location in conduit 14. A pressure transducer or pressure switch 26 may be employed to sense the pressure in conduit 14. When it senses a slight negative pressure indicative of an inhalation it provides a signal to pressure source 12 to provide the positive pressure flow to assist in the inhalation by the patient 16 and provides a signal over line 28. Alternatively, pressure transducer or pressure switch 26 may be replaced by a flow sensor 26 a, FIG. 4, or any other suitable device which can sense the beginning of an inhalation by patient 16, for example, electrodes, strain gauges, or chest strap devices may be put on or around the patient's body or chest cavity to sense the beginning of an inhalation independent of the actual airflow characteristics in the airway of the patient.
  • Pressure source 12, FIG. 5, may include a conventional blower 30 which provides a positive pressure during the inhale cycle in line 32 at positive pressure port 34 and a negative pressure during exhale in line 36 at negative pressure port 38. Dwell port 40 is provided for connection to ambient or atmospheric pressure, and may also include a flow restrictor 41 to make the sensor 26 more sensitive when it is, for example, a pressure sensor or pressure switch. Programmed timer 42, FIG. 5, drives actuator device or actuator motor 44 which through eccentric drive 46 moves swinger 48 of slider valve 50 from positive port 34 to negative port 38, then to dwell port 40. Swinger 48 remains there until sensor 26 senses that a patient inhalation has begun, at which point it sends a signal on line 28 to program timer 42 to once again operate actuator motor 44 to move slider switch 50 through the cycle of positive port 34, negative port 38 and dwell port 40.
  • Programmed timer 42 may include a timer 60, FIG. 6, which operates driver circuit 62 that causes actuator motor 44 to step through the three positions of swinger 48: positive port 34, negative port 38, and dwell port 40. An alternate output 59 of the timer 60 (or of driver 62) indicates when the driver 62 is holding the swinger 48 at the dwell port 40, and provides one input to AND gate 66. When pressure sensor 26 senses that a patient inhalation is beginning it also provides an input to AND gate 66. When both those inputs are present at AND gate 66 it provides an output on line 28 to timer 60 to start the cycle again beginning with connection of swinger 48 to positive port 34.
  • Although specific features of the invention are shown in some drawings and not in others, this is for convenience only as each feature may be combined with any or all of the other features in accordance with the invention. The words “including”, “comprising”, “having”, and “with” as used herein are to be interpreted broadly and comprehensively and are not limited to any physical interconnection. Moreover, any embodiments disclosed in the subject application are not to be taken as the only possible embodiments.
  • Other embodiments will occur to those skilled in the art and are within the following claims:

Claims (7)

1. An improved insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase comprising:
a conduit for connection to a patient's airway;
a pressure source with a positive pressure port and a negative pressure port;
a sensor system for sensing an inhalation by the patient; and
a controller system for driving said switching device to connect said conduit sequentially to said positive port, said negative port and said dwell port and to return again to said positive port in response to said sensor system sensing an inhalation by the patient when said conduit is connected to said dwell port.
2. The improved insufflation-exsufflation system of claim 1 in which said switching device includes a selector valve and an actuator device.
3. The improved insufflation-exsufflation system of claim 1 in which said sensor system includes a pressure sensor in said conduit.
4. The improved insufflation-exsufflation system of claim 1 in which said sensor system includes an airflow detector in said conduit.
5. The improved insufflation-exsufflation system of claim 1 in which said controller system includes a programmed timer.
6. The improved insufflation-exsufflation system of claim 1 in which said dwell port is connected to atmospheric pressure.
7. The improved insufflation-exsufflation system of claim 1 in which said dwell port includes a restrictor portion to increase sensitivity.
US10/657,405 2003-09-08 2003-09-08 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase Expired - Lifetime US6860265B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
US10/657,405 US6860265B1 (en) 2003-09-08 2003-09-08 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase
CA2537353A CA2537353C (en) 2003-09-08 2004-09-02 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase
AU2004271999A AU2004271999B2 (en) 2003-09-08 2004-09-02 Insufflation-exsufflation system for removal of pulmonary secretions
PCT/US2004/028522 WO2005025477A2 (en) 2003-09-08 2004-09-02 Insufflation-exsufflation system for removal of pulmonary secretions
AT04782919T ATE539787T1 (en) 2003-09-08 2004-09-02 INSUFFLATION-EXSUFFLATION SYSTEM FOR THE REMOVAL OF BRONCHOPULMONARY SECRETS WITH AUTOMATIC TRIGGER OF THE INHALATION PHASE
CNB200480025702XA CN100512899C (en) 2003-09-08 2004-09-02 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase
JP2006525428A JP4617308B2 (en) 2003-09-08 2004-09-02 Inhalation / expiration system to remove bronchopulmonary secretions that automatically trigger the inhalation phase
EP04782919A EP1663361B1 (en) 2003-09-08 2004-09-02 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase
IL174058A IL174058A (en) 2003-09-08 2006-03-02 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/657,405 US6860265B1 (en) 2003-09-08 2003-09-08 Insufflation-exsufflation system for removal of broncho-pulmonary secretions with automatic triggering of inhalation phase

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US20050039749A1 true US20050039749A1 (en) 2005-02-24
US6860265B1 US6860265B1 (en) 2005-03-01

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Publication number Priority date Publication date Assignee Title
US20070240492A1 (en) * 2006-04-12 2007-10-18 Dileo Anthony Filter with memory, communication and pressure sensor
US20090098021A1 (en) * 2006-04-12 2009-04-16 Dileo Anthony Filter with memory, communication and concentration sensor
US20090225808A1 (en) * 2006-04-12 2009-09-10 Dileo Anthony Filter with memory, communication and temperature sensor
WO2011045735A1 (en) * 2009-10-16 2011-04-21 Koninklijke Philips Electronics N.V. System and method for suctioning for secretion removal from the airway of a mechanically ventilated subject
US20110094310A1 (en) * 2006-04-12 2011-04-28 Millipore Corporation Filter with memory, communication and pressure sensor
WO2012042255A1 (en) * 2010-09-28 2012-04-05 Noel Martin Davis Treatment device and method of use
WO2012080892A1 (en) * 2010-12-13 2012-06-21 Koninklijke Philips Electronics N.V. Exsufflation synchronization
WO2012158394A3 (en) * 2011-05-13 2013-01-17 Lung Assist, Inc. Mechanical insufflation/exsufflation airway clearance apparatus
WO2013033589A1 (en) * 2011-09-02 2013-03-07 University Of Medicine And Dentistry Of New Jersey Manual insufflator-exsufflator
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US20130255689A1 (en) * 2012-03-27 2013-10-03 Seoil Pacific Corp. Direction switching valve unit and cough assisting device using the same
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US20140116441A1 (en) * 2011-06-29 2014-05-01 Koninklijke Philips N.V. Method and apparatus for assisting airway clearance
WO2014188286A1 (en) 2013-05-20 2014-11-27 Flaem Nuova S.P.A. Equipment for rehabilitative respiratory physiotherapy
US20150059753A1 (en) * 2012-03-21 2015-03-05 Koninklijke Phillips N.V. System and method for controlling insufflation pressure during inexsufflation
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US20150231348A1 (en) * 2012-08-20 2015-08-20 Koninklijke Philips N.V. Synchronizing mechanical in-exsufflation and diaphragmatic pacing
WO2015138924A1 (en) * 2014-03-14 2015-09-17 The Johns Hopkins University Device for the emulation of a cough in ventilated patients
US20160030691A1 (en) * 2013-04-03 2016-02-04 Koninklijke Philips N.V. Critical care ventilator with mouth piece ventilation
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WO2017122910A1 (en) * 2016-01-13 2017-07-20 (주)서일퍼시픽 Portable in-exsufflator
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US20180043116A1 (en) * 2012-12-03 2018-02-15 Mhs Care-Innovation, Llc Combination respiratory therapy device, system and method
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EP3569277A1 (en) * 2009-08-11 2019-11-20 ResMed Motor Technologies Inc. Ventilator comprising a single stage, axial symmetric blower
US10518048B2 (en) 2015-07-31 2019-12-31 Hill-Rom Services, PTE Ltd. Coordinated control of HFCWO and cough assist devices
WO2020161471A1 (en) * 2019-02-04 2020-08-13 Camcon Medical Limited A valve actuation assembly and a system for controlling a supply of gas for inhalation by a user
US10821244B2 (en) 2013-07-18 2020-11-03 Drägerwerk AG & Co. KGaA Medical measuring device, ventilator and method for operating a medical measuring device or for operating a ventilator
US10905837B2 (en) * 2015-04-02 2021-02-02 Hill-Rom Services Pte. Ltd. Respiratory therapy cycle control and feedback
US11529275B2 (en) * 2017-07-18 2022-12-20 Hill-Rom Services Pte. Ltd. Combination respiratory therapy and mattress functionality system integrated into a patient bed

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1326671B1 (en) * 2000-10-19 2009-02-04 Mallinckrodt Inc. Ventilator with dual gas supply
IL145461A (en) * 2001-09-16 2006-09-05 Alyn Woldenberg Family Hospita Inexsufflator
EP3064242A1 (en) 2003-04-28 2016-09-07 Advanced Circulatory Systems Inc. Ventilator and methods for treating head trauma and low blood circulation
CA2621760A1 (en) * 2005-09-26 2007-05-18 Eliezer Be'eri Combined ventilator inexsufflator
US8256417B2 (en) * 2005-11-23 2012-09-04 Curative (Beijing) Medical Technology Co., Ltd. Method and apparatus for providing positive airway pressure to a patient
WO2007144767A2 (en) * 2006-02-02 2007-12-21 Be Eri Eliezer A respiratory apparatus
ATE527008T1 (en) 2006-10-20 2011-10-15 Metrohealth System MANUAL LUNG VENTILATOR
US9352111B2 (en) 2007-04-19 2016-05-31 Advanced Circulatory Systems, Inc. Systems and methods to increase survival with favorable neurological function after cardiac arrest
US8151790B2 (en) 2007-04-19 2012-04-10 Advanced Circulatory Systems, Inc. Volume exchanger valve system and method to increase circulation during CPR
US8251876B2 (en) 2008-04-22 2012-08-28 Hill-Rom Services, Inc. Breathing exercise apparatus
US8752546B2 (en) * 2008-04-23 2014-06-17 General Electric Company System and method for mobilizing occlusions from a breathing tube
US8485183B2 (en) 2008-06-06 2013-07-16 Covidien Lp Systems and methods for triggering and cycling a ventilator based on reconstructed patient effort signal
CA2686149C (en) * 2008-11-17 2016-11-01 The Metrohealth System Combination lung ventilation and mucus clearance apparatus and method
US9724266B2 (en) 2010-02-12 2017-08-08 Zoll Medical Corporation Enhanced guided active compression decompression cardiopulmonary resuscitation systems and methods
US9259546B2 (en) 2010-12-21 2016-02-16 Koninklijke Philips N.V. Ventilator with integrated blower to provide negative or positive pressure in a ventilator system
US8783250B2 (en) 2011-02-27 2014-07-22 Covidien Lp Methods and systems for transitory ventilation support
US8714154B2 (en) 2011-03-30 2014-05-06 Covidien Lp Systems and methods for automatic adjustment of ventilator settings
WO2013068918A1 (en) * 2011-11-07 2013-05-16 Koninklijke Philips Electronics N.V. Systems and methods for intra-pulmonary percussive ventilation integrated in a ventilator
JP2015500733A (en) 2011-12-19 2015-01-08 レスキューシステムズ インコーポレイテッドＲｅｓｑｓｙｓｔｅｍｓ，Ｉｎｃ． Intrathoracic pressure regulation system and method for treatment
US9180271B2 (en) 2012-03-05 2015-11-10 Hill-Rom Services Pte. Ltd. Respiratory therapy device having standard and oscillatory PEP with nebulizer
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
US9811634B2 (en) 2013-04-25 2017-11-07 Zoll Medical Corporation Systems and methods to predict the chances of neurologically intact survival while performing CPR
US20140358047A1 (en) 2013-05-30 2014-12-04 ResQSystems, Inc. End-tidal carbon dioxide and amplitude spectral area as non-invasive markers of coronary perfusion pressure and arterial pressure
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US10265495B2 (en) 2013-11-22 2019-04-23 Zoll Medical Corporation Pressure actuated valve systems and methods
US9808591B2 (en) 2014-08-15 2017-11-07 Covidien Lp Methods and systems for breath delivery synchronization
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
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Citations (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1044031A (en) * 1908-10-01 1912-11-12 Johann Heinrich Draeger Method of causing artificial respiration.
US1169995A (en) * 1909-02-10 1916-02-01 Roscoe S Prindle Method of producing artificial respiration.
US1358893A (en) * 1913-10-21 1920-11-16 Stolle Georg Paul Eugen Method for producing artificial respiration
US2364626A (en) * 1942-11-09 1944-12-12 John H Emerson Resuscitator
US2428451A (en) * 1945-02-17 1947-10-07 John H Emerson Pressure resuscitator
US2468741A (en) * 1944-12-12 1949-05-03 John H Emerson Breathing apparatus
US2481299A (en) * 1944-12-12 1949-09-06 John H Emerson Breathing apparatus
US2774347A (en) * 1954-03-17 1956-12-18 John H Emerson Apparatus for producing artificial respiration
US2774348A (en) * 1952-05-31 1956-12-18 John H Emerson Artificial respirator
US2853998A (en) * 1955-02-28 1958-09-30 John H Emerson Respirator casing and methods of producing the same
US2861568A (en) * 1950-09-27 1958-11-25 Quilter John Raymond Cuthbert Pressurized helmet for aviators
US2914064A (en) * 1957-03-14 1959-11-24 Sandelowsky Werner Respirators
US2918917A (en) * 1955-03-02 1959-12-29 John H Emerson Apparatus for vibrating portions of a patient's airway
US3357428A (en) * 1963-12-23 1967-12-12 David L Carlson Respiratory augmentor with electronic monitor and control
US3368212A (en) * 1964-12-08 1968-02-06 J H Emerson Company Gas flow monitor
US3402711A (en) * 1964-01-06 1968-09-24 Westinghouse Electric Corp Breathing apparatus
US3768468A (en) * 1970-01-21 1973-10-30 British Oxygen Co Ltd Ventilators
US3794026A (en) * 1970-07-29 1974-02-26 H Jacobs Ventilating apparatus embodying selective volume or pressure operation and catheter means for use therewith
US3850170A (en) * 1972-07-26 1974-11-26 Us Army Oxygen powered volume cycled respirator with oxygen air mix
US3976064A (en) * 1975-03-11 1976-08-24 Wood William W Intermittent mandatory assisted ventilation system for positive pressure breathing apparatus
US4193406A (en) * 1978-09-18 1980-03-18 Jinotti Walter J Dual purpose catheter
US4206754A (en) * 1976-06-02 1980-06-10 Boc Limited Lung ventilators
US4273120A (en) * 1978-02-27 1981-06-16 Submarine Products Limited Underwater breathing apparatus
US4281651A (en) * 1977-05-06 1981-08-04 Airco, Inc. Lung ventilator
US4393869A (en) * 1981-06-22 1983-07-19 Canadian Patents & Development Limited Electronically controlled respirator
US4565194A (en) * 1982-02-06 1986-01-21 Dragerwerk Ag Tracheal tube for artificial respiration
US5127398A (en) * 1989-04-19 1992-07-07 Cis-Lunar Development Laboratories, Inc. Breathing apparatus mouthpiece
US5311862A (en) * 1988-11-14 1994-05-17 Blasdell Richard J Inhalation apparatus
US5400778A (en) * 1990-06-18 1995-03-28 Siemens-Elema Ab Method and device for reduction of rebreathing of gas from dead space
US5419768A (en) * 1991-03-07 1995-05-30 Aeros Instruments, Inc. Electrical medical vacuum regulator
US5673689A (en) * 1995-02-09 1997-10-07 Puritan Bennett Corporation Piston based ventilator
US5850835A (en) * 1996-03-28 1998-12-22 Suzuki Motor Corporation Respirator system
US5988166A (en) * 1994-06-01 1999-11-23 Dranez Anstalt Ventilator apparatus
US6209540B1 (en) * 1998-03-31 2001-04-03 Suzuki Corporation Artificial respiration apparatus
US6402711B1 (en) * 1999-08-10 2002-06-11 Richard S. Nauert Knee brace operating hinge
US6595213B2 (en) * 2000-01-25 2003-07-22 Siemens Elema Ab High-frequency oscillator ventilator

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2512621A (en) 1944-11-23 1950-06-27 John H Emerson Therapeutic vibrator
DE946258C (en) * 1950-07-12 1956-07-26 Draegerwerk Ag Respirator
DE1255865B (en) * 1962-10-06 1967-12-07 Draegerwerk Ag Control valve for ventilators
US3653379A (en) 1970-08-20 1972-04-04 Joseph G Glenn Adjustable pressure ippb ventilator
US3972327A (en) * 1973-03-22 1976-08-03 Hoffmann-La Roche Inc. Respirator
US4054134A (en) 1975-09-15 1977-10-18 Kritzer Richard W Respirators
US4062358A (en) 1976-04-21 1977-12-13 Kritzer Richard W Respirators
FR2538705B1 (en) 1982-12-29 1987-12-31 Vincent Michel MEDICAL APPARATUS FOR THE EXSUFFLATION OF TIRES
US4595004A (en) 1984-09-17 1986-06-17 Kurt Czech Apparatus for the treatment of the lungs of humans or animals
US4977889A (en) 1989-10-12 1990-12-18 Regents Of The University Of Minnesota Fitting and tuning chest compression device
US5280784A (en) 1990-09-19 1994-01-25 Paul Ritzau Pari-Werk Gmbh Device in particular and inhalating device for treating the lung and the respiratory tracts
US5645537A (en) 1993-04-20 1997-07-08 Advanced Cytometrix, Inc. Aspiration needle and syringe for use therewith, apparatus incorporating the same and kit for use in fine needle aspiration cytology, and method
FR2733917B1 (en) * 1995-05-12 1997-10-17 Benarrouch Jacques OSCILLATORY PRESSURE VARIATOR TO REDUCE THE VISCOSITY OF THIXOTROPIC MUCUS FOR THEIR EXPECTORATION OF LUNGS AND BRONCHES
US5611335A (en) 1995-06-06 1997-03-18 Makhoul; Imad R. High-frequency fan ventilator
US5829429A (en) 1997-04-21 1998-11-03 Hughes; Arthur R. Acoustic respiratory therapy apparatus
US6058932A (en) 1997-04-21 2000-05-09 Hughes; Arthur R. Acoustic transceiver respiratory therapy apparatus
SE9904382D0 (en) 1999-12-02 1999-12-02 Siemens Elema Ab High Frequency Oscillation Patient Fan System
WO2002006673A1 (en) 2000-07-13 2002-01-24 Electromed, Inc. Body pulsating method and apparatus
EP1326671B1 (en) * 2000-10-19 2009-02-04 Mallinckrodt Inc. Ventilator with dual gas supply
DE10131653C2 (en) * 2001-06-29 2003-07-03 Map Medizin Technologie Gmbh Method and device for supplying a breathing gas
IL145461A (en) * 2001-09-16 2006-09-05 Alyn Woldenberg Family Hospita Inexsufflator

Patent Citations (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1044031A (en) * 1908-10-01 1912-11-12 Johann Heinrich Draeger Method of causing artificial respiration.
US1169995A (en) * 1909-02-10 1916-02-01 Roscoe S Prindle Method of producing artificial respiration.
US1358893A (en) * 1913-10-21 1920-11-16 Stolle Georg Paul Eugen Method for producing artificial respiration
US2364626A (en) * 1942-11-09 1944-12-12 John H Emerson Resuscitator
US2468741A (en) * 1944-12-12 1949-05-03 John H Emerson Breathing apparatus
US2481299A (en) * 1944-12-12 1949-09-06 John H Emerson Breathing apparatus
US2428451A (en) * 1945-02-17 1947-10-07 John H Emerson Pressure resuscitator
US2861568A (en) * 1950-09-27 1958-11-25 Quilter John Raymond Cuthbert Pressurized helmet for aviators
US2774348A (en) * 1952-05-31 1956-12-18 John H Emerson Artificial respirator
US2774347A (en) * 1954-03-17 1956-12-18 John H Emerson Apparatus for producing artificial respiration
US2853998A (en) * 1955-02-28 1958-09-30 John H Emerson Respirator casing and methods of producing the same
US2918917A (en) * 1955-03-02 1959-12-29 John H Emerson Apparatus for vibrating portions of a patient's airway
US2914064A (en) * 1957-03-14 1959-11-24 Sandelowsky Werner Respirators
US3357428A (en) * 1963-12-23 1967-12-12 David L Carlson Respiratory augmentor with electronic monitor and control
US3402711A (en) * 1964-01-06 1968-09-24 Westinghouse Electric Corp Breathing apparatus
US3368212A (en) * 1964-12-08 1968-02-06 J H Emerson Company Gas flow monitor
US3768468A (en) * 1970-01-21 1973-10-30 British Oxygen Co Ltd Ventilators
US3794026A (en) * 1970-07-29 1974-02-26 H Jacobs Ventilating apparatus embodying selective volume or pressure operation and catheter means for use therewith
US3850170A (en) * 1972-07-26 1974-11-26 Us Army Oxygen powered volume cycled respirator with oxygen air mix
US3976064A (en) * 1975-03-11 1976-08-24 Wood William W Intermittent mandatory assisted ventilation system for positive pressure breathing apparatus
US4206754A (en) * 1976-06-02 1980-06-10 Boc Limited Lung ventilators
US4281651A (en) * 1977-05-06 1981-08-04 Airco, Inc. Lung ventilator
US4273120A (en) * 1978-02-27 1981-06-16 Submarine Products Limited Underwater breathing apparatus
US4193406A (en) * 1978-09-18 1980-03-18 Jinotti Walter J Dual purpose catheter
US4393869A (en) * 1981-06-22 1983-07-19 Canadian Patents & Development Limited Electronically controlled respirator
US4565194A (en) * 1982-02-06 1986-01-21 Dragerwerk Ag Tracheal tube for artificial respiration
US5311862A (en) * 1988-11-14 1994-05-17 Blasdell Richard J Inhalation apparatus
US5127398A (en) * 1989-04-19 1992-07-07 Cis-Lunar Development Laboratories, Inc. Breathing apparatus mouthpiece
US5400778A (en) * 1990-06-18 1995-03-28 Siemens-Elema Ab Method and device for reduction of rebreathing of gas from dead space
US5419768A (en) * 1991-03-07 1995-05-30 Aeros Instruments, Inc. Electrical medical vacuum regulator
US5988166A (en) * 1994-06-01 1999-11-23 Dranez Anstalt Ventilator apparatus
US5673689A (en) * 1995-02-09 1997-10-07 Puritan Bennett Corporation Piston based ventilator
US5850835A (en) * 1996-03-28 1998-12-22 Suzuki Motor Corporation Respirator system
US6209540B1 (en) * 1998-03-31 2001-04-03 Suzuki Corporation Artificial respiration apparatus
US6402711B1 (en) * 1999-08-10 2002-06-11 Richard S. Nauert Knee brace operating hinge
US6595213B2 (en) * 2000-01-25 2003-07-22 Siemens Elema Ab High-frequency oscillator ventilator

Cited By (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110094310A1 (en) * 2006-04-12 2011-04-28 Millipore Corporation Filter with memory, communication and pressure sensor
US20070240492A1 (en) * 2006-04-12 2007-10-18 Dileo Anthony Filter with memory, communication and pressure sensor
US20090225808A1 (en) * 2006-04-12 2009-09-10 Dileo Anthony Filter with memory, communication and temperature sensor
US20110020181A1 (en) * 2006-04-12 2011-01-27 Millipore Corporation Filter with memory, communication and concentration sensor
US20110016953A1 (en) * 2006-04-12 2011-01-27 Millipore Corporation Filter with memory, communication and pressure sensor
US20110017062A1 (en) * 2006-04-12 2011-01-27 Millipore Corporation Filter with memory, communication and pressure sensor
US20110036782A1 (en) * 2006-04-12 2011-02-17 Millipore Corporation Filter with memory, communication and temperature sensor
US20110084024A1 (en) * 2006-04-12 2011-04-14 Millipore Corporation Filter with memory, communication and concentration sensor
US8221522B2 (en) 2006-04-12 2012-07-17 Emd Millipore Corporation Filter with memory, communication and pressure sensor
US20090098021A1 (en) * 2006-04-12 2009-04-16 Dileo Anthony Filter with memory, communication and concentration sensor
US20110083491A1 (en) * 2006-04-12 2011-04-14 Millipore Corporation Filter with memory, communication and pressure sensor
US20110094951A1 (en) * 2006-04-12 2011-04-28 Millipore Corporation Filter with memory, communication and pressure sensor
US20110100134A1 (en) * 2006-04-12 2011-05-05 Millipore Corporation Filter with memory, communication and pressure sensor
US8007568B2 (en) 2006-04-12 2011-08-30 Millipore Corporation Filter with memory, communication and pressure sensor
US8084259B2 (en) 2006-04-12 2011-12-27 Millipore Corporation Method of insuring the integrity of a filtering element
US8137983B2 (en) 2006-04-12 2012-03-20 Emd Millipore Corporation Method of maintaining a protein concentration at a tangential flow filter
US8147757B2 (en) 2006-04-12 2012-04-03 Emd Millipore Corporation Filter with memory, communication and concentration sensor
EP3569277A1 (en) * 2009-08-11 2019-11-20 ResMed Motor Technologies Inc. Ventilator comprising a single stage, axial symmetric blower
US10874810B2 (en) 2009-08-11 2020-12-29 Resmed Motor Technologies Inc. Single stage, axial symmetric blower and portable ventilator
EP4059553A1 (en) * 2009-08-11 2022-09-21 ResMed Motor Technologies Inc. Modular ventilator system
WO2011045735A1 (en) * 2009-10-16 2011-04-21 Koninklijke Philips Electronics N.V. System and method for suctioning for secretion removal from the airway of a mechanically ventilated subject
US10537700B2 (en) 2009-10-16 2020-01-21 Koninklijke Philips N.V. System and method for suctioning for secretion removal from the airway of a mechanically ventilated subject
US11547830B2 (en) 2009-10-16 2023-01-10 Koninklijke Philips N.V. System and method for suctioning for secretion removal from the airway of a mechanically ventilated subject
JP2013521860A (en) * 2010-03-09 2013-06-13 ペン−センチュリー インコーポレイテッド Device and method for aerosol delivery to the lungs or other locations in the body
WO2012042255A1 (en) * 2010-09-28 2012-04-05 Noel Martin Davis Treatment device and method of use
GB2498121A (en) * 2010-09-28 2013-07-03 Noel Martin Davis Treatment device and method of use
US10272222B2 (en) * 2010-09-28 2019-04-30 Breas Medical Limited Treatment device and method of use
US20130220325A1 (en) * 2010-09-28 2013-08-29 Noel Martin Davis Treatment device and method of use
AU2011309905B2 (en) * 2010-09-28 2014-10-09 Breas Medical Limited Treatment device and method of use
GB2498121B (en) * 2010-09-28 2013-10-16 Noel Martin Davis Treatment device and method of use
WO2012080892A1 (en) * 2010-12-13 2012-06-21 Koninklijke Philips Electronics N.V. Exsufflation synchronization
US9901691B2 (en) 2010-12-13 2018-02-27 Koninklijke Philips N.V. Exsufflation synchronization
CN103260680A (en) * 2010-12-13 2013-08-21 皇家飞利浦电子股份有限公司 Exsufflation synchronization
WO2012158394A3 (en) * 2011-05-13 2013-01-17 Lung Assist, Inc. Mechanical insufflation/exsufflation airway clearance apparatus
US8539952B2 (en) 2011-05-13 2013-09-24 Hill-Rom Services Pte. Ltd. Mechanical insufflation/exsufflation airway clearance apparatus
US10183134B2 (en) 2011-05-13 2019-01-22 Hill-Rom Services Pte. Ltd. Insufflation/exsufflation airway clearance apparatus
US8985112B2 (en) 2011-05-13 2015-03-24 Hill-Rom Services Pte. Ltd. Insufflation/exsufflation airway clearance apparatus
US20140116441A1 (en) * 2011-06-29 2014-05-01 Koninklijke Philips N.V. Method and apparatus for assisting airway clearance
WO2013033589A1 (en) * 2011-09-02 2013-03-07 University Of Medicine And Dentistry Of New Jersey Manual insufflator-exsufflator
US10500356B2 (en) * 2012-03-21 2019-12-10 Koninklijke Philips N.V. System and method for controlling insufflation pressure during inexsufflation
US20150059753A1 (en) * 2012-03-21 2015-03-05 Koninklijke Phillips N.V. System and method for controlling insufflation pressure during inexsufflation
US9345851B2 (en) * 2012-03-27 2016-05-24 Seoil Pacific Corp Direction switching valve unit and cough assisting device using the same
US20130255689A1 (en) * 2012-03-27 2013-10-03 Seoil Pacific Corp. Direction switching valve unit and cough assisting device using the same
ITBS20120105A1 (en) * 2012-07-06 2014-01-07 Flaem Nuova Spa EQUIPMENT FOR RESPIRATORY PHYSIOTHERAPY
US20150231348A1 (en) * 2012-08-20 2015-08-20 Koninklijke Philips N.V. Synchronizing mechanical in-exsufflation and diaphragmatic pacing
US10137262B2 (en) * 2012-08-20 2018-11-27 Koninklijke Philips N.V. Synchronizing mechanical in-exsufflation and diaphragmatic pacing
US20180043116A1 (en) * 2012-12-03 2018-02-15 Mhs Care-Innovation, Llc Combination respiratory therapy device, system and method
US10814082B2 (en) * 2012-12-03 2020-10-27 Mhs Care-Innovation, Llc Combination respiratory therapy device, system and method
US20160030691A1 (en) * 2013-04-03 2016-02-04 Koninklijke Philips N.V. Critical care ventilator with mouth piece ventilation
US20160067431A1 (en) * 2013-05-20 2016-03-10 Flaem Nuova S.P.A. Equipment for rehabilitative respiratory physiotherapy
WO2014188286A1 (en) 2013-05-20 2014-11-27 Flaem Nuova S.P.A. Equipment for rehabilitative respiratory physiotherapy
US10821244B2 (en) 2013-07-18 2020-11-03 Drägerwerk AG & Co. KGaA Medical measuring device, ventilator and method for operating a medical measuring device or for operating a ventilator
WO2015032503A1 (en) 2013-09-05 2015-03-12 Physio-Assist Equipment for treating an obstructive respiratory disorder
FR3009967A1 (en) * 2013-09-05 2015-03-06 Physio Assist EQUIPMENT FOR TREATING AN OBSTRUCTIVE RESPIRATORY DISORDER
WO2015138924A1 (en) * 2014-03-14 2015-09-17 The Johns Hopkins University Device for the emulation of a cough in ventilated patients
US10905837B2 (en) * 2015-04-02 2021-02-02 Hill-Rom Services Pte. Ltd. Respiratory therapy cycle control and feedback
US10518048B2 (en) 2015-07-31 2019-12-31 Hill-Rom Services, PTE Ltd. Coordinated control of HFCWO and cough assist devices
CN105381570A (en) * 2015-12-29 2016-03-09 中国人民解放军成都军区总医院 Portable and intelligent type respiration training device and method
WO2017122910A1 (en) * 2016-01-13 2017-07-20 (주)서일퍼시픽 Portable in-exsufflator
CN107648711A (en) * 2016-05-20 2018-02-02 长庚医疗财团法人林口长庚纪念医院 Aeration equipment and method
US11529275B2 (en) * 2017-07-18 2022-12-20 Hill-Rom Services Pte. Ltd. Combination respiratory therapy and mattress functionality system integrated into a patient bed
WO2020161471A1 (en) * 2019-02-04 2020-08-13 Camcon Medical Limited A valve actuation assembly and a system for controlling a supply of gas for inhalation by a user
CN110101945A (en) * 2019-05-07 2019-08-09 濡新（北京）科技发展有限公司 It is a kind of to synchronize automatic expectoration method and system

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WO2005025477A2 (en) 2005-03-24
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IL174058A (en) 2010-03-28
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ATE539787T1 (en) 2012-01-15
CN1849149A (en) 2006-10-18
JP4617308B2 (en) 2011-01-26
EP1663361A4 (en) 2010-12-01
US6860265B1 (en) 2005-03-01
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CN100512899C (en) 2009-07-15
EP1663361A2 (en) 2006-06-07

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