US20050016542A1 - Intra-tracheal aerosol delivery system and method of using same - Google Patents
Intra-tracheal aerosol delivery system and method of using same Download PDFInfo
- Publication number
- US20050016542A1 US20050016542A1 US10/884,080 US88408004A US2005016542A1 US 20050016542 A1 US20050016542 A1 US 20050016542A1 US 88408004 A US88408004 A US 88408004A US 2005016542 A1 US2005016542 A1 US 2005016542A1
- Authority
- US
- United States
- Prior art keywords
- medication
- sub
- tube
- patient
- distal end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/04—Tracheal tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/04—Tracheal tubes
- A61M16/0475—Tracheal tubes having openings in the tube
- A61M16/0477—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
- A61M16/0484—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids at the distal end
Definitions
- the present invention relates to a device for facilitating medicating a patient and more particular to a patient care device that facilitates delivering a therapeutic aerosol by endotracheal means deep into the lungs of a patient.
- Delivery of medications into the lungs of a patient is generally accomplished in two different ways, e.g. either or by directly delivering a liquid bolus of the drug or by insertion of a delivery catheter through the larynx or through an artificial airway such as endotracheal or by a tracheostomy tube.
- an endotracheal tube poses a particular problem since the endotracheal tube operates as a significant site of impaction of an externally generated therapeutic aerosol.
- some endotracheal tube materials may promote aerosol rainout while the presence of an electrostatic charge on the tube itself can also reduce the ability of the aerosol to pass through the tube. Therefore, it would be highly desirable to have a new and improved method and apparatus for delivering a therapeutic aerosol by endotracheal means deep into the lungs of a patient.
- An aerosol delivery system includes an endotracheal tube with a sub-port having a sufficient diameter to permit the passage of a sub-port tube therethrough.
- the sub-port tube passes within the interior of the endotracheal tube via the sub-port and includes a passageway that terminates in an atomizer nozzle at the distal end of the sub-port tube.
- the atomizer nozzle and the endotracheal tube are integrally connected to one another at a distal end base outlet of the endotracheal tube.
- a delivery conduit having an atomizer connector at its distal end is adapted to be connected to a canister for delivering fluid under pressure.
- the delivery conduit has a sufficient length to pass within the sub-port tube to lockingly engage the atomizer nozzle atomizer, whereby fluid delivered under pressure from the canister flows to the atomizer nozzle causing an aerosol mist to be dispensed outwardly from the base outlet of the endotracheal tube.
- FIG. 1 is a perspective view of a intra-tracheal aerosol delivery system, which is constructed in accordance with the present invention
- FIG. 2 is an enlarged cross sectional view of a patient care device taken along lines 2 - 2 of FIG. 1 ;
- FIG. 3 is an enlarged fragmentary view of a distal end portion of the patient care device of FIG. 1 ;
- FIG. 4 is a perspective view of a medication delivery device for use with the patient care device of FIG. 1 ;
- FIGS. 1-4 there is illustrated an intra-tracheal aerosol delivery system 10 , which is constructed in accordance with the preferred embodiment of the present invention.
- the intra-tracheal aerosol delivery system 10 is designed to maximize lower respiratory tract deposition of aerosol particles generated by a meter dose inhaler.
- the novel method of delivering an aerosol fluid medication to the distal end portion of a endotracheal tube optimizes particle size for distal airway penetration, as well as reduces local mucosal impact and irritation.
- the system 10 generally includes a patient care device 12 and a medication delivery device 14 .
- the patient care device 12 facilitates ventilating a patient (not shown) while the medication delivery device 14 facilitates medicating a patient.
- the patient care device 12 and the medication delivery device 14 cooperate together to optimize aerosol particle size for distal airway penetration, providing an improved and more efficient method of aerosol delivery in mechanically ventilated patients.
- the patient care device 12 generally includes a curved endotracheal tube 16 having a proximal end opening 18 , a distal end opening 20 and a sub-port opening 22 .
- An atomizer nozzle 24 is molded to the distal end of the endotracheal tube 16 and extends slightly out from the distal end opening 20 to allow the delivery of a spray mist beyond the distal end of the endotracheal tube 16 .
- there is no drug waste running down the interior wall of the endotracheal tube 16 thereby allowing a clinician to know exactly how much drug is delivered to the patient.
- the patient care device 12 facilitates atomizing drugs directly into the lungs of a patient without interruption of the ventilating process.
- the unique and novel method of delivering an aerosol spray mist beyond the tip of the endotracheal tube 16 results in more rapid and higher peak lung levels than nebulized or endotracheally injected medication.
- the patient care device 12 also includes a sub-port tube 26 that is molded between the endotracheal tube 16 and the atomizer nozzle 24 at about the distal end 20 of the endotracheal tube 16 .
- the atomizer nozzle 24 extends out from the distal end of the sub-port tube 26 a sufficient distance to permit the nozzle 24 to be molded to the interior wall of the endotracheal tube 16 at about its distal end and to extend beyond the distal end 20 of the endotracheal tube 16 by about a distance D.
- the distance D is between about 0.2 centimeters and about 0.0 centimeter.
- a more preferred distance D is between about 0.1 centimeters and about 0.0 centimeters, while the most preferred distance D is about 0.0 centimeters.
- the nozzle 24 and the sub-port tube 26 are integrally attached to one another and integrally attached to the interior wall of the endotracheal tube 16 at about its distal end 20 to insure that neither the nozzle 24 nor the sub-port tube 26 can invade the lungs or trachea of the patient. This is an important feature of the preferred embodiment of the present invention.
- the sub-port tube 26 is integrally attached to the interior wall of the endotracheal tube 16 and exits the endotracheal tube 16 at the sub-port opening 22 , where it extends out from the endotracheal tube 16 a sufficient distance to be easily accessed by a clinician for drug delivery purposes and without interfering with the connection between the endotracheal tube 16 and a mechanical ventilator (not shown).
- that portion of the sub-port tube 26 that extends out from the endotracheal tube 20 is between about 10 millimeters in length and about 150 millimeters in length.
- a more preferred length is between about 50 millimeters and about 140 millimeters, while the most preferred length is about 120 millimeters.
- the exiting of the sub-port tube 26 through the sub-port opening 22 and not the proximal end opening 18 of the endotracheal tube 16 is an important feature of the preferred embodiment of the present invention as this facilitates drug delivery without interrupting the ventilation process.
- a clinician is able to oxygenate, ventilate and medicate with the aerosol delivery system 10 .
- the medication delivery device 14 generally includes an elongated delivery conduit 28 having a proximal end opening 30 and a distal end opening 32 .
- a nozzle or atomizer connector 34 is disposed in the distal end opening 32 of the delivery conduit 28 and extends out therefrom a sufficient distance to be received and lockingly engage a seat 36 disposed at the proximal end of the nozzle 24 .
- a fluid tight seal is formed.
- the seal is an important feature of the preferred embodiment of the present invention as it allows fluid under pressure to be delivered from a canister 38 to the atomizer nozzle 24 without loss of pressure.
- the seat 36 is constructed to release the atomizer connector 34 when the delivery conduit 28 is pulled by its proximal end to be extracted from the sub-port tube 26 .
- a clinician inserts the patient care device 12 through either the mouth or nose of a patient so that the distal end of the patient care device 12 is disposed in the trachea of the patient.
- This action also positions the proximal end 18 of the endotracheal tube 16 and the proximal end 30 of the sub-port tube 26 at desired positions for attachment to the mechanical ventilator (not shown) and the medication delivery device 14 respectively.
- the method of attaching the endotracheal tube 16 is well known to those skilled in the art, this method will not be described hereinafter in greater detail.
- the clinician removes a small passageway plug 40 from the proximal end of the sub-port tube 26 .
- the clinician attaches the proximal end of the delivery conduit 28 to the canister 38 and then directs the distal end of the delivery conduit 28 into the sub-port tube 26 .
- the delivery conduit 28 and its associated nozzle connector 34 each have a sufficiently small diameter to enter the distal end of the sub-port tube 26 and to pass therethrough to cause the nozzle connector 34 to be received within the atomizer nozzle seat 36 .
- the delivery conduit 28 is sufficiently stiff to allow the nozzle connector 34 to be pushed into locking engagement with the seat 36 by pushing on the proximal end of the delivery conduit 28 .
- the clinician attaches the proximal end of the delivery conduit 28 to an outlet of the canister 38 .
- the clinician actuates a thumb lever 42 disposed on the top of the canister 38 to deliver a precise dosage of medication to the nozzle 24 .
- the nozzle 24 upon receiving the fluid under pressure immediately transforms the fluid into small aerosol particles that emerge from beyond the distal end 20 of the endotracheal tube 16 for delivery into the distal airways of the patient.
- the clinician disengages the proximal end of the delivery conduit 28 from the canister 38 and pulls the free proximal end of the delivery conduit 28 to disengage the nozzle connector 34 from the nozzle 24 .
- the delivery conduit 28 is then extracted from the sub-port tube 26 . Once the delivery conduit 28 has been removed from the sub-port tube 26 the proximal end of the sub-port tube 26 is sealed with the air passageway plug 40 .
Abstract
An aerosol delivery system includes an endotracheal tube with a sub-port having a sufficient diameter to permit the passage of a sub-port tube therethrough. The sub-port tube passes within the interior of the endotracheal tube via the sub-port and includes a passageway that terminates in an atomizer nozzle at the distal end of the sub-port tube. The atomizer nozzle and the endotracheal tube are integrally connected to one another at a distal end base outlet of the endotracheal tube. A delivery conduit having an atomizer connector at its distal end is adapted to be connected to a canister for delivering fluid under pressure. The delivery conduit has a sufficient length to pass within the sub-port tube to lockingly engage the atomizer nozzle atomizer, whereby fluid delivered under pressure from the canister flows to the atomizer nozzle causing an aerosol mist to be dispensed from the endotracheal tube atomizer nozzle.
Description
- The present invention relates to a device for facilitating medicating a patient and more particular to a patient care device that facilitates delivering a therapeutic aerosol by endotracheal means deep into the lungs of a patient.
- Delivery of medications into the lungs of a patient is generally accomplished in two different ways, e.g. either or by directly delivering a liquid bolus of the drug or by insertion of a delivery catheter through the larynx or through an artificial airway such as endotracheal or by a tracheostomy tube. However, the presence of an endotracheal tube poses a particular problem since the endotracheal tube operates as a significant site of impaction of an externally generated therapeutic aerosol. Moreover, some endotracheal tube materials may promote aerosol rainout while the presence of an electrostatic charge on the tube itself can also reduce the ability of the aerosol to pass through the tube. Therefore, it would be highly desirable to have a new and improved method and apparatus for delivering a therapeutic aerosol by endotracheal means deep into the lungs of a patient.
- An aerosol delivery system includes an endotracheal tube with a sub-port having a sufficient diameter to permit the passage of a sub-port tube therethrough. The sub-port tube passes within the interior of the endotracheal tube via the sub-port and includes a passageway that terminates in an atomizer nozzle at the distal end of the sub-port tube. The atomizer nozzle and the endotracheal tube are integrally connected to one another at a distal end base outlet of the endotracheal tube. A delivery conduit having an atomizer connector at its distal end is adapted to be connected to a canister for delivering fluid under pressure. The delivery conduit has a sufficient length to pass within the sub-port tube to lockingly engage the atomizer nozzle atomizer, whereby fluid delivered under pressure from the canister flows to the atomizer nozzle causing an aerosol mist to be dispensed outwardly from the base outlet of the endotracheal tube.
- The above mentioned features and steps of the invention and the manner of attaining them will become apparent, and the invention itself will be best understood by reference to the following description of the embodiments of the invention in conjunction with the accompanying drawings wherein:
-
FIG. 1 is a perspective view of a intra-tracheal aerosol delivery system, which is constructed in accordance with the present invention; -
FIG. 2 is an enlarged cross sectional view of a patient care device taken along lines 2-2 ofFIG. 1 ; -
FIG. 3 is an enlarged fragmentary view of a distal end portion of the patient care device ofFIG. 1 ; -
FIG. 4 is a perspective view of a medication delivery device for use with the patient care device ofFIG. 1 ; - Referring now to the drawings and more particularly to
FIGS. 1-4 there is illustrated an intra-trachealaerosol delivery system 10, which is constructed in accordance with the preferred embodiment of the present invention. The intra-trachealaerosol delivery system 10 is designed to maximize lower respiratory tract deposition of aerosol particles generated by a meter dose inhaler. As will be explained hereinafter in greater detail, the novel method of delivering an aerosol fluid medication to the distal end portion of a endotracheal tube optimizes particle size for distal airway penetration, as well as reduces local mucosal impact and irritation. - Considering now the intra-tracheal
aerosol delivery system 10 in greater detail with reference toFIG. 1 , thesystem 10 generally includes apatient care device 12 and amedication delivery device 14. Thepatient care device 12 facilitates ventilating a patient (not shown) while themedication delivery device 14 facilitates medicating a patient. Thepatient care device 12 and themedication delivery device 14 cooperate together to optimize aerosol particle size for distal airway penetration, providing an improved and more efficient method of aerosol delivery in mechanically ventilated patients. - Considering now the
patient care device 12 in greater detail with reference toFIG. 1 , thepatient care device 12 generally includes a curvedendotracheal tube 16 having a proximal end opening 18, a distal end opening 20 and asub-port opening 22. Anatomizer nozzle 24 is molded to the distal end of theendotracheal tube 16 and extends slightly out from the distal end opening 20 to allow the delivery of a spray mist beyond the distal end of theendotracheal tube 16. In short, there is no drug waste running down the interior wall of theendotracheal tube 16 thereby allowing a clinician to know exactly how much drug is delivered to the patient. Moreover, thepatient care device 12 facilitates atomizing drugs directly into the lungs of a patient without interruption of the ventilating process. The unique and novel method of delivering an aerosol spray mist beyond the tip of theendotracheal tube 16 results in more rapid and higher peak lung levels than nebulized or endotracheally injected medication. - In order to allow medication delivery without interruption of the ventilation process, the
patient care device 12 also includes asub-port tube 26 that is molded between theendotracheal tube 16 and theatomizer nozzle 24 at about thedistal end 20 of theendotracheal tube 16. In this regard, theatomizer nozzle 24 extends out from the distal end of the sub-port tube 26 a sufficient distance to permit thenozzle 24 to be molded to the interior wall of theendotracheal tube 16 at about its distal end and to extend beyond thedistal end 20 of theendotracheal tube 16 by about a distance D. In the preferred embodiment of the present invention the distance D is between about 0.2 centimeters and about 0.0 centimeter. A more preferred distance D is between about 0.1 centimeters and about 0.0 centimeters, while the most preferred distance D is about 0.0 centimeters. - From the foregoing, it should be understood by those skilled in the art, that the
nozzle 24 and thesub-port tube 26 are integrally attached to one another and integrally attached to the interior wall of theendotracheal tube 16 at about itsdistal end 20 to insure that neither thenozzle 24 nor thesub-port tube 26 can invade the lungs or trachea of the patient. This is an important feature of the preferred embodiment of the present invention. - The
sub-port tube 26 is integrally attached to the interior wall of theendotracheal tube 16 and exits theendotracheal tube 16 at the sub-port opening 22, where it extends out from the endotracheal tube 16 a sufficient distance to be easily accessed by a clinician for drug delivery purposes and without interfering with the connection between theendotracheal tube 16 and a mechanical ventilator (not shown). - In this regard, that portion of the
sub-port tube 26 that extends out from theendotracheal tube 20 is between about 10 millimeters in length and about 150 millimeters in length. A more preferred length is between about 50 millimeters and about 140 millimeters, while the most preferred length is about 120 millimeters. The exiting of thesub-port tube 26 through the sub-port opening 22 and not the proximal end opening 18 of theendotracheal tube 16 is an important feature of the preferred embodiment of the present invention as this facilitates drug delivery without interrupting the ventilation process. In short, a clinician is able to oxygenate, ventilate and medicate with theaerosol delivery system 10. - Considering now the
medication delivery device 14 in greater detail with reference toFIGS. 1-4 , themedication delivery device 14 generally includes anelongated delivery conduit 28 having a proximal end opening 30 and a distal end opening 32. A nozzle oratomizer connector 34 is disposed in thedistal end opening 32 of thedelivery conduit 28 and extends out therefrom a sufficient distance to be received and lockingly engage aseat 36 disposed at the proximal end of thenozzle 24. In this regard, when theatomizer connector 34 is received within the seat 36 a fluid tight seal is formed. The seal is an important feature of the preferred embodiment of the present invention as it allows fluid under pressure to be delivered from acanister 38 to theatomizer nozzle 24 without loss of pressure. Thereby a fully pressurized dose of a desired drug can be delivered into the distal airways of the patient. As will be explained hereinafter in greater detail, theseat 36 is constructed to release theatomizer connector 34 when thedelivery conduit 28 is pulled by its proximal end to be extracted from thesub-port tube 26. - Considering now the unique and novel method of ventilating and medicating a patient in accordance with the preferred embodiment of the present invention, a clinician inserts the
patient care device 12 through either the mouth or nose of a patient so that the distal end of thepatient care device 12 is disposed in the trachea of the patient. This action also positions theproximal end 18 of theendotracheal tube 16 and theproximal end 30 of thesub-port tube 26 at desired positions for attachment to the mechanical ventilator (not shown) and themedication delivery device 14 respectively. As the method of attaching theendotracheal tube 16 is well known to those skilled in the art, this method will not be described hereinafter in greater detail. - Considering now the method of attaching the
medication delivery device 14 to thepatient care device 12 in greater detail, the clinician removes asmall passageway plug 40 from the proximal end of thesub-port tube 26. Next the clinician attaches the proximal end of thedelivery conduit 28 to thecanister 38 and then directs the distal end of the delivery conduit 28 into thesub-port tube 26. In this regard, the delivery conduit 28 and its associatednozzle connector 34 each have a sufficiently small diameter to enter the distal end of thesub-port tube 26 and to pass therethrough to cause thenozzle connector 34 to be received within theatomizer nozzle seat 36. In this regard, thedelivery conduit 28 is sufficiently stiff to allow thenozzle connector 34 to be pushed into locking engagement with theseat 36 by pushing on the proximal end of thedelivery conduit 28. - Once the
nozzle connector 34 has been engaged with theseat 36, the clinician attaches the proximal end of thedelivery conduit 28 to an outlet of thecanister 38. With a fluid passageway having now been established between thecanister 38 and thenozzle 24, the clinician actuates athumb lever 42 disposed on the top of thecanister 38 to deliver a precise dosage of medication to thenozzle 24. Thenozzle 24 upon receiving the fluid under pressure immediately transforms the fluid into small aerosol particles that emerge from beyond thedistal end 20 of theendotracheal tube 16 for delivery into the distal airways of the patient. - After the patient has been medicated, the clinician disengages the proximal end of the
delivery conduit 28 from thecanister 38 and pulls the free proximal end of thedelivery conduit 28 to disengage thenozzle connector 34 from thenozzle 24. Thedelivery conduit 28 is then extracted from thesub-port tube 26. Once thedelivery conduit 28 has been removed from thesub-port tube 26 the proximal end of thesub-port tube 26 is sealed with theair passageway plug 40. - While particular embodiments of the present invention have been disclosed, it is to be understood that various different modifications are possible and are contemplated within the true spirit and scope of the appended claims. There is no intention, therefore, of limitations to the exact abstract or disclosure herein presented.
Claims (9)
1-4. (cancelled).
5. (presently amended) a method of medicating a ventilated patient, comprising the steps of:
providing an endotracheal tube having a sub-port tube with an atomizer nozzle disposed at a distal end section thereof said atomizer nozzle being integrally connected to a distal end portion of said endotracheal tube and integrally connected to a distal end portion of said sub-port tube to facilitate securing said atomizer nozzle;
said atomizer nozzle having a seat disposed at a proximal end portion thereof, said seat being adapted to lockingly engage a connector seat disposed at a distal end section of an elongated medication delivery tube to form a fluid tight seal to facilitate delivering medication under pressure as an aerosol mist to the lungs of a patient;
inserting said endotracheal tube into the airway passage of the patient;
passing a delivery conduit having a nozzle connector disposed at its distal end through said sub-port tube a sufficient distance to seat said nozzle connector into said connector seat;
attaching a proximal end of said delivery conduit to a canister of medicated fluid under pressure; and
releasing a sufficient amount of the medicated fluid under pressure from said canister for delivery to the lungs of the ventilated patient through said atomizer nozzle.
6-11. (Cancelled).
12. In combination with an endotracheal tube having a sub-port tube with an atomizer nozzle disposed at a distal end section thereof, said atomizer nozzle being connected to a distal end portion of the endotracheal tube and to a distal end portion of the sub-port tube to facilitate delivering an aerosol mist to the lung of a patient, a medication delivery device, comprising:
a canister having a medication and propellant disposed therein for further facilitating delivering the medication under pressure as the aerosol mist to the lung of the patient.
13. The medication delivery device according to claim 12 , wherein said canister includes a thumb lever for actuating the delivery of a sufficient amount of the medication fluid under pressure to facilitate medicating a patient.
14. The medication delivery device according to claim 13 , wherein said sufficient amount of medication fluid under pressure is a predetermined dosage amount.
15. A medication delivery device, comprising;
a canister having a medication and propellant disposed therein for facilitating delivery of the medication under pressure as the aerosol mist to the lung of a patient;
an elongated medication delivery tube adapted to be connected at one of its ends to said canister and further adapted to be connected at another one of its ends to a nozzle connector to facilitate coupling the canister to a supported nozzle connector seat and fluid atomizer disposed within the airway passage of the patient.
16. The medication delivery device according to claim 15 , wherein said canister includes a thumb lever for actuating the delivery of a sufficient amount of the medication fluid under pressure to facilitate medicating a patient.
17. The medication delivery device according to claim 16 , wherein said sufficient amount of medication fluid under pressure is a predetermined dosage amount.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/884,080 US20050016542A1 (en) | 2003-05-05 | 2004-07-03 | Intra-tracheal aerosol delivery system and method of using same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/431,811 US6766801B1 (en) | 2003-05-05 | 2003-05-05 | Intra-tracheal aerosol delivery system and method of using same |
US10/884,080 US20050016542A1 (en) | 2003-05-05 | 2004-07-03 | Intra-tracheal aerosol delivery system and method of using same |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/431,811 Division US6766801B1 (en) | 2003-05-05 | 2003-05-05 | Intra-tracheal aerosol delivery system and method of using same |
Publications (1)
Publication Number | Publication Date |
---|---|
US20050016542A1 true US20050016542A1 (en) | 2005-01-27 |
Family
ID=32712974
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/431,811 Expired - Fee Related US6766801B1 (en) | 2003-05-05 | 2003-05-05 | Intra-tracheal aerosol delivery system and method of using same |
US10/884,080 Abandoned US20050016542A1 (en) | 2003-05-05 | 2004-07-03 | Intra-tracheal aerosol delivery system and method of using same |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/431,811 Expired - Fee Related US6766801B1 (en) | 2003-05-05 | 2003-05-05 | Intra-tracheal aerosol delivery system and method of using same |
Country Status (1)
Country | Link |
---|---|
US (2) | US6766801B1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8162898B1 (en) | 2005-04-18 | 2012-04-24 | Venetec International, Inc. | Venipuncture base plate assembly and method of using same |
WO2015200582A1 (en) * | 2014-06-25 | 2015-12-30 | Neomend, Inc. | Pleural air leak test system |
US9409003B2 (en) | 2012-12-07 | 2016-08-09 | Cook Medical Technologies, LLC | System for reducing local discomfort |
US20170311954A1 (en) * | 2016-04-28 | 2017-11-02 | Wieslaw Mieczyslaw Brodaczewski | Polymeric ligating clip |
US11000658B2 (en) | 2014-05-18 | 2021-05-11 | Awair, Inc. | Device to reduce discomfort in the upper airway |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6766801B1 (en) * | 2003-05-05 | 2004-07-27 | Medical Device Group, Inc. | Intra-tracheal aerosol delivery system and method of using same |
US20050245890A1 (en) * | 2004-03-15 | 2005-11-03 | Jackson David L | Device and method for delivering biological agents to the respiratory system of test animals |
US7494107B2 (en) * | 2005-03-30 | 2009-02-24 | Supercritical Systems, Inc. | Gate valve for plus-atmospheric pressure semiconductor process vessels |
GB2444779A (en) * | 2006-12-14 | 2008-06-18 | Archibald Ian Jeremy Brain | A laryngeal mask with with drug delivery means |
US9084722B2 (en) | 2008-12-05 | 2015-07-21 | University of Pittsburgh—of the Commonwealth System of Higher Education | Biologic scaffold for prevention of pulmonary fibrosis |
US9265904B2 (en) | 2009-07-06 | 2016-02-23 | Teleflex Life Sciences | Artificial airway |
US20110030680A1 (en) * | 2009-07-30 | 2011-02-10 | Nellcor Puritan Bennett Llc | Tracheal tube with drug delivery device and method of using the same |
US9528897B2 (en) | 2009-08-13 | 2016-12-27 | Chimden Medical Pty Ltd | Pressure indicator |
US9032951B2 (en) | 2010-08-24 | 2015-05-19 | Trudell Medical International | Aerosol delivery device |
GB201016562D0 (en) | 2010-10-01 | 2010-11-17 | Laryngeal Mask Company The Ltd | Artificial airway device |
JP5922135B2 (en) | 2010-10-15 | 2016-05-24 | ザ ラリンジアル マスク カンパニー リミテッド | Artificial airway device |
US10549054B2 (en) | 2011-02-02 | 2020-02-04 | Teleflex Life Sciences Unlimited Company | Artificial airway |
GB201120628D0 (en) | 2011-11-30 | 2012-01-11 | Laryngeal Mask Company The Ltd | Endoscopy device |
US9597466B2 (en) * | 2014-03-12 | 2017-03-21 | R. J. Reynolds Tobacco Company | Aerosol delivery system and related method, apparatus, and computer program product for providing control information to an aerosol delivery device via a cartridge |
CN111388852A (en) * | 2020-04-23 | 2020-07-10 | 乐恩(北京)医药技术有限公司 | Air flue humidifying device, air flue nursing appliance and air flue humidifying method |
US11166841B1 (en) | 2021-01-29 | 2021-11-09 | Lubin Martinez | Snoring and sleep apnea prevention device and methods |
Citations (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4669463A (en) * | 1984-02-22 | 1987-06-02 | Mcconnell Richard B | Endotracheal tube injection site addition |
US4881541A (en) * | 1988-12-21 | 1989-11-21 | The Regents Of The University Of California | Vaporizer for an anesthetic having a vapor pressure about one atmosphere |
US4969878A (en) * | 1986-03-18 | 1990-11-13 | Christoph Schmidt | Thick-walled flexible probe for insertion in the trachea or respectively in the bronchial system |
US5025806A (en) * | 1990-04-16 | 1991-06-25 | Ballard Medical Products | Medical ventilating and a spirating apparatus and methods |
US5031613A (en) * | 1989-06-07 | 1991-07-16 | JoAnne Hahn | Nebulizing catheter |
US5078131A (en) * | 1990-05-21 | 1992-01-07 | Trudell Medical | Introduction of medication in ventilator circuit |
US5438982A (en) * | 1992-03-10 | 1995-08-08 | Macintyre; Neil R. | Endotracheal tube adapted for aerosol generation at distal end thereof |
US5605147A (en) * | 1995-02-24 | 1997-02-25 | Truthan; Charles E. | Endotracheal tube insert with needleless medication injection port |
US5642730A (en) * | 1994-06-17 | 1997-07-01 | Trudell Medical Limited | Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister |
US5803078A (en) * | 1994-05-06 | 1998-09-08 | Brauner; Mark E. | Methods and apparatus for intrapulmonary therapy and drug administration |
US5964223A (en) * | 1994-06-17 | 1999-10-12 | Trudell Medical Limited | Nebulizing catheter system and methods of use and manufacture |
US6009868A (en) * | 1995-08-31 | 2000-01-04 | Astra Ab | Arrangement in a spray tube mouthpiece |
US6237597B1 (en) * | 1998-12-14 | 2001-05-29 | Kovac Joann | Endotracheal medication port adapter |
US6415788B1 (en) * | 1999-07-02 | 2002-07-09 | Enternet Medical, Inc. | Apparatus for treating respiratory gases including liquid trap |
US6575944B1 (en) * | 2000-06-19 | 2003-06-10 | Portex, Inc. | Adapter for localized treatment through a tracheal tube and method for use thereof |
US20030172934A1 (en) * | 2002-03-15 | 2003-09-18 | Croll Perry W. | Medical atomizer |
US20040007236A1 (en) * | 2002-03-15 | 2004-01-15 | Mcgee Thomas E. | Endotracheal surfactant distribution system |
US6729334B1 (en) * | 1994-06-17 | 2004-05-04 | Trudell Medical Limited | Nebulizing catheter system and methods of use and manufacture |
US6766801B1 (en) * | 2003-05-05 | 2004-07-27 | Medical Device Group, Inc. | Intra-tracheal aerosol delivery system and method of using same |
-
2003
- 2003-05-05 US US10/431,811 patent/US6766801B1/en not_active Expired - Fee Related
-
2004
- 2004-07-03 US US10/884,080 patent/US20050016542A1/en not_active Abandoned
Patent Citations (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4669463A (en) * | 1984-02-22 | 1987-06-02 | Mcconnell Richard B | Endotracheal tube injection site addition |
US4969878A (en) * | 1986-03-18 | 1990-11-13 | Christoph Schmidt | Thick-walled flexible probe for insertion in the trachea or respectively in the bronchial system |
US4881541A (en) * | 1988-12-21 | 1989-11-21 | The Regents Of The University Of California | Vaporizer for an anesthetic having a vapor pressure about one atmosphere |
US5031613A (en) * | 1989-06-07 | 1991-07-16 | JoAnne Hahn | Nebulizing catheter |
US5025806A (en) * | 1990-04-16 | 1991-06-25 | Ballard Medical Products | Medical ventilating and a spirating apparatus and methods |
US5078131A (en) * | 1990-05-21 | 1992-01-07 | Trudell Medical | Introduction of medication in ventilator circuit |
US5438982A (en) * | 1992-03-10 | 1995-08-08 | Macintyre; Neil R. | Endotracheal tube adapted for aerosol generation at distal end thereof |
US5803078A (en) * | 1994-05-06 | 1998-09-08 | Brauner; Mark E. | Methods and apparatus for intrapulmonary therapy and drug administration |
US5964223A (en) * | 1994-06-17 | 1999-10-12 | Trudell Medical Limited | Nebulizing catheter system and methods of use and manufacture |
US5642730A (en) * | 1994-06-17 | 1997-07-01 | Trudell Medical Limited | Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister |
US6079413A (en) * | 1994-06-17 | 2000-06-27 | Trudell Medical Limited | Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister |
US6526976B1 (en) * | 1994-06-17 | 2003-03-04 | Trudell Medical Limited | Nebulizing catheter system and method of use and manufacture |
US6729334B1 (en) * | 1994-06-17 | 2004-05-04 | Trudell Medical Limited | Nebulizing catheter system and methods of use and manufacture |
US5605147A (en) * | 1995-02-24 | 1997-02-25 | Truthan; Charles E. | Endotracheal tube insert with needleless medication injection port |
US6009868A (en) * | 1995-08-31 | 2000-01-04 | Astra Ab | Arrangement in a spray tube mouthpiece |
US6237597B1 (en) * | 1998-12-14 | 2001-05-29 | Kovac Joann | Endotracheal medication port adapter |
US6415788B1 (en) * | 1999-07-02 | 2002-07-09 | Enternet Medical, Inc. | Apparatus for treating respiratory gases including liquid trap |
US6575944B1 (en) * | 2000-06-19 | 2003-06-10 | Portex, Inc. | Adapter for localized treatment through a tracheal tube and method for use thereof |
US20030172934A1 (en) * | 2002-03-15 | 2003-09-18 | Croll Perry W. | Medical atomizer |
US20040007236A1 (en) * | 2002-03-15 | 2004-01-15 | Mcgee Thomas E. | Endotracheal surfactant distribution system |
US6766801B1 (en) * | 2003-05-05 | 2004-07-27 | Medical Device Group, Inc. | Intra-tracheal aerosol delivery system and method of using same |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8162898B1 (en) | 2005-04-18 | 2012-04-24 | Venetec International, Inc. | Venipuncture base plate assembly and method of using same |
US9409003B2 (en) | 2012-12-07 | 2016-08-09 | Cook Medical Technologies, LLC | System for reducing local discomfort |
US9744340B2 (en) | 2012-12-07 | 2017-08-29 | Cook Medical Technologies Llc | System for reducing local discomfort |
US10363403B2 (en) | 2012-12-07 | 2019-07-30 | Cook Medical Technologies Llc | System for reducing local discomfort |
US11690987B2 (en) | 2012-12-07 | 2023-07-04 | Awair, Inc. | System for reducing local discomfort |
US11000658B2 (en) | 2014-05-18 | 2021-05-11 | Awair, Inc. | Device to reduce discomfort in the upper airway |
WO2015200582A1 (en) * | 2014-06-25 | 2015-12-30 | Neomend, Inc. | Pleural air leak test system |
US10300223B2 (en) | 2014-06-25 | 2019-05-28 | Neomend, Inc. | Pleural air leak test system |
US20170311954A1 (en) * | 2016-04-28 | 2017-11-02 | Wieslaw Mieczyslaw Brodaczewski | Polymeric ligating clip |
Also Published As
Publication number | Publication date |
---|---|
US6766801B1 (en) | 2004-07-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6766801B1 (en) | Intra-tracheal aerosol delivery system and method of using same | |
EP0687478B1 (en) | Improved catheter system for delivery of aerosolized medicine for use with pressurized propellant canister | |
AU2021225190B2 (en) | Nasal cannula | |
AU674843B2 (en) | Endotracheal tube having aerosol generating means | |
US5031613A (en) | Nebulizing catheter | |
EP3244950B1 (en) | Respiratory interface | |
US7204245B2 (en) | Aerosol enhancement device | |
CN204364581U (en) | Be used to provide the system of respiratory therapy | |
JPH08508670A (en) | Continuous flow adapter for nebulizer | |
KR20210049719A (en) | Breath-enhanced nebulizer for the delivery of aerosolized drugs to ventilated patients | |
RU95109450A (en) | Methods for drug delivery to the respiratory system, the mode of delivery of the drug in one or both lungs of patients who are not inserted an endotracheal tube, METHOD aerosol delivery of drug in the lungs of patients: methods for drug delivery to a branched region of the respiratory system, the patient, the delivery catheter aerosol MEDICINES FOR LUNG PATIENTS (OPTIONS): CATHETER SYSTEM FOR DELIVERY OF AEROSOL OF MEDICINES IN LUNG PATIENTS, CATHETER SYSTEM A FOR DELIVERY aerosol therapy the patient's lungs, the suction catheter FOR A tracheal tube and method of making catheters for spraying liquids with gas | |
US20150224278A1 (en) | Nebulized ventilation system | |
US20100065062A1 (en) | Temporary pharyngeal airway | |
JPH08511976A (en) | Intratracheal tube to which aerosol is diverted and supplied by Murphy Eye | |
US20170368276A1 (en) | Aerosol Medication Delivery System And Method | |
CN2860505Y (en) | Atomizing inhalator for trachea incision | |
CN209984730U (en) | Artificial airway atomizer | |
US20210236758A1 (en) | Respiratory interface | |
WO2023095019A1 (en) | Tracheal administering device and atomizing catheter | |
US20030150462A1 (en) | Aerosol delivery apparatus-ventilator connector with adapter (VCA) and medicament dispenser and adapter (MDA) | |
CA2596438A1 (en) | Nebulizing catheter system and methods of use and manufacture | |
CA2042929A1 (en) | Tidal aerosol drug system requiring assisted respiration | |
SK5416Y1 (en) | Multiple-nozzle bidirectional pressure generator for ventilation of lungs |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: MEDICAL DEVICE GROUP, INC., CALIFORNIA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:WRIGHT, CLIFFORD A.;REEL/FRAME:017093/0334 Effective date: 20030904 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |
|
AS | Assignment |
Owner name: IAPYX MEDICAL, INC., NEVADA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:WRIGHT, CLIFFORD A.;REEL/FRAME:029842/0828 Effective date: 20130205 |