US1929247A - Syringe equipment and apparatus - Google Patents

Syringe equipment and apparatus Download PDF

Info

Publication number
US1929247A
US1929247A US509958A US50995831A US1929247A US 1929247 A US1929247 A US 1929247A US 509958 A US509958 A US 509958A US 50995831 A US50995831 A US 50995831A US 1929247 A US1929247 A US 1929247A
Authority
US
United States
Prior art keywords
nipple
container
vial
syringe
tubular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US509958A
Inventor
George N Hein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to US509958A priority Critical patent/US1929247A/en
Application granted granted Critical
Publication of US1929247A publication Critical patent/US1929247A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2496Ampoule holder connected to rest of syringe via pivot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2429Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31586Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle

Definitions

  • Fig. '71 is a longitudinal section of vial and 70 closure with portion of a modified form of piston end.
  • a tubular needle casing -27 is removably mounted on the needle base and has its opposite end preferably sealed by a closure cork 28.
  • the casing preferably has an outer diameter similar to the inner diameter of the container body, so that it may be transposed and used as a plunger 13 (see dotted lines v' Fig. 4).
  • the closure cork in the casing is provided with a recess 29 which engages the pro.- iection 12 of the snugly slidable cork 9, and axially aligns cork and piston.' l
  • nipple structure for inverted syringes are shown in Figs. 6 and '7.
  • a threaded ferrule 46 is provided so that the nipple may be threadedly engaged by a suitably threaded piston head, if desired.
  • a nipple structure is disclosed wherein the outer face of the nipple is provided with an annular groove or recess 3n into which the edges of the piston head seat, and'thus provide for the manufacturing advantage of reducing the depth of recess 8.

Description

@et 39 w33. G. NT Hem SYRINGE EQUIPMENT AND APPARATUS 2 Sheets-Sheet l Filed Jan. 20, 1931 wimwaluammmam'agw N VEN TOR.
' ATTORNEY @CL 3' R933. G. N. HEIN SYRINGE EQUIPMENT AND APPARATUS Filed Jan. 20,11931 2 Sheets-Sheet 2 A TTORNEY Patented Qct. 3, 1933 u PATENT oFFicE- uiTED STATES 3 Ciairns,
rEhis invention relates to syringe equipment and particularly to syringes in which it is desired to expel liquids from an original container wherein the contents are sealed against impurities or foreign matter, and which are readily adaptable to packaging of a number of units in a container, so that it is not necessary to transfer the contents to separate dispensing containers at time of use. Such syringes are highly desirable in the dental and medical professions for subcutaneous and venous injections, and in other situations where it is advantageous to have fluid dispensed from a normally closed container vial.
The invention lherein may also be used in dispensing apparatus employing the syringe principle of expulsion of contents of a vial by pressure, and is adaptable to use with pastes and plastic materials equally with uids.
Among the objects of the invention are to provide a container vial adaptable to packaging of a number of vial units in a container, and Wherein the contents of the vials may be placed therein at point of manufacture and the contents expelled direct from the vial, either completely vor in portions without exposing the vial contents to extraneous impurities; to -provide for closing said contents within the vial against impurities; to provide a closure for vials which permits the contents of the vial to be discharged through a discharge orice by pressure thereon, and which automatically closes upon cessation of the pressure; to provide apparatus to expel the contents of such containers by hand pressure and'by mechanical leverage and to provide apparatus whereby such apparatus may be mounted upon and operated on a wall or bracket support.
With the above mentioned and other objects in view, the invention consists in the novel construction and combination of parts hereinafter described, illustrated in the accompanying drawings and pointed out in the claims hereto appended; it being understood that various changes in the form, proportion, size and minor details of construction within the scope of the claims may be resorted to without departing from the spirit or sacrificing any of the advantages of the invention.
To more clearly comprehend the invention, reference is directed to the accompanying drawings,
wherein- Fig. 1 is a longitudinal section of vial body and closure members.
Fig. 2 is a longitudinal section of vial body of Fig. 1 in operative mounting in a syringe frame.
(Ci. M13-2id) bers in syringe forming relation, and an end adapted for mounting of injection needle, and a needle casing with casing transposed to a plunger shown in dotted lines.
Fig. 5 is a longitudinal section of syringe assembly showing inverted type syringe wherein y the vial is a plunger and the closure is a piston head.
Fig. 6 is a longitudinal section of vial for inverted syringe, with threaded closure.`
Fig. '71 is a longitudinal section of vial and 70 closure with portion of a modified form of piston end.
Fig. 8 is a vertical section of side View of vial support for wall mounting with vial mounted therein and plunger threadedly operable.
Fig. 9 is a side View vertical section of wall mounting bracket with vial depending vertically therein.
Fig. l0 is a vertical elevation in section of vial showing inverted type of use in a counter or table dispenser.l l Fig. 11 is a longitudinal section of vial threaded at each end to engage other syringe forming equipment.
rl.here are two .general groups of vial syringes and dispensers, one of which is known as the regular type, wherein a plunger is received.- in one end of the container and by pressure discharges the fluid from the opposite end of the container, as illustrated in Figs. 2 and 4, and the other type known as the inverted type in which the container is open at one end only, said open end being slidably mounted over avtubular piston, the container per se being the plunger member, as shown in Figs. 5, 6 and 7.
The vial is of a type suited to the expelling equipment with which it is to be used. Fig. 1 shows a vial for use in a regular syringe having a frame with a plunger opposite the discharge end.
Fig. i shows a vial for use without a vial frame 100 and wherein a plunger support may be threadedly attached to one end of the vial and a tubular needle attached to the discharge end of the vial, whereas Figs. 5, 6 and 7 show the container or vial used with the inverted type of syringe in which 106.
it is necessary to have one end only of the container or vial open.
Application of the 'invention to dispensing of liquids or pastes for all purposes and of all kinds,
is merely a matter'A of degree in change of size 110 vided externally 'of the danse 24. v A As illustrated in the varying modided structures of suitable body-forming material, preferably transparent, such as glass, and having an opening at a discharge end 2, whereat is mounted a discharge nipple 3 which is slidable axially internally of the tubular body and tightly engages the internal walls of the discharge end, as at 4, so as to close theopening thereof against leakage.
The nipple s has a may or elastic raster-iai, auch as resilient rubber, and through its wall is provided with a discharge opening 5 which is preferably a puncture or incision without removal of material of the nipple, such as a slit made with a razor blade or a puncture made with a sharp instrument, so that the elastic material, by reason of its elasticity or resiliency will lspring together upon withdrawal of the incision instrument, so as to close the opening of the slit or puncture against normal opening, but leaving the slit or puncture open in the sense that upon pressure within the container, the elasticity or resiliency of the material will cause the walls of the slit or puncture to spread apart -so as to permit discharge of the contents of the container.
The nipple is preferably provided with an arrially extended tubular portion 6, into which the slit or puncture 5 opens, the tubuiar portion having an opening at its opposite end into the container body, as at 8.
In containers or vials which` have one end open only and are intended'for the inverted type of syringe or dispenser, (see Figs. 6, 7 and 10), the nipple is the only closure required for the container, and is axially slidable therein, and thereby acts as a sealing cork when the container is not being operated, and as a dispenser and a piston head during operation to expel the contents oi the container.
In the containers or'vials which have an opening at both ends and are intended for syringes of regular type, (see Figs. l and 4), the nipple is preferably positively positioned relative to the discharge end opening 2, so as not to be blown Y from its seat at the discharge end of the vial, as
by la circumferential shoulder 22 which provides apbase seated within the container. abutting a flange 24 which extends radially inward of the container wall. A shoulder 23 may also be pro` of nipples shown in the respective views. the part of the tubular portion 6 which has the puncture or slit 5 therein extends axially beyond the shoulder or base portion 22, providing a discharge yorifice which, in opening responsive to pressure within the tubular body, is not required to overcome the resistance ofthe resilient pressure of radial material in the shoulder or base 22 and thus permits extrusion of the vial contents upon exertion of considerably less pressure within the tubular body than would otherwise be required and prevents sudden spurts of material in filling a cannula just prior'to an injection.
1n containers for vials for usewith the regular type of syringes or dispensers, a closure cork 9 is provided for what may be termed the illling end of the tubular container body, the cork being preferably of resilient material, such as rubber.
The cork closure 9 has snug slidable fit with the inner wall of the container, andpreferably is provided with end faces 10 connected by a side wall which preferably has one or more circumferential grooves ll which permits ease of sliding by providing for a minimum of frictional contact between the cork and container walls. One end face of the cork 9 is preferably provided with a projection 12, which may have corrugations or threads 12a, adapted to be engaged by one end of a plunger member 13, which may be threaded, as at 13a to positively engage corresponding threads of the projection 12, to axially rotate the cork, or move it in either direction.'
The container has thus far been described as solely a discharging device. jections it is desirable that a syringe be capable of drawing blood from a vein. to insure that a vein Ahas actually been entered by 'the injection needle, prior to injection. For this purpose, a double ended tubular injection needle is used `(see Fig. 3), one end of the(` cannula 14 extending free into a recess 15 in the needle base 16. and adapted to pass through the puncture 5 and to be closely gripped by the resilient walls thereof when rthe punctured portion 'of the nipple body is received .within said rec'ess .15.. Thus, prior to injection, the plunger 13 and the cork 9 may be drawn outwardly to cause suction of venous blood into the container, which immediately notifies the operator that a vein has been punctured and the plunger is then depressed inwardly to discharge the fluid and complete the injection.
For use of the vial in Fig. l, a syringe frame 17 is provided which may be fenestrated, as at 17, to afford view therethrough, and the frame mountsA at one end a needle base 16, as by threads 18, the base being provided with recess l5 into which the end of the resilient nipple is snugly received, so that the wall of the recess forms a In entrevenous in-` support against the walls of the nipple and intended axially of the tube to provide a tubular neck 25, preferably threaded externally and adapted to mount a needle base having a cannula 26 and having recess 15 threaded to engage the threads of the container neck. A tubular needle casing -27 is removably mounted on the needle base and has its opposite end preferably sealed by a closure cork 28. The casing preferably has an outer diameter similar to the inner diameter of the container body, so that it may be transposed and used as a plunger 13 (see dotted lines v' Fig. 4). The closure cork in the casing is provided with a recess 29 which engages the pro.- iection 12 of the snugly slidable cork 9, and axially aligns cork and piston.' l
In the inverted type of syringe (see Figs. 5, 6 and 7), the container vial 30, with its closure nipple 3 are mounted at an end of a tubular shaft 31 having its discharge end 32 adapted to mount an injection needle. The opposite end of the tubular shaft is provided with a head 33 which is preferably removable by means of threads 34 and is provided with recess' 85 into which the punctured portion 5 of the nipple 'is received. Upon depression of the container 30 over the piston head 33, the nipple 3 is receded in the vial ico and the contents are expelled through the puncture 5 which opens under pressure and discharges the vial contents through the tubular shaft and needle. Upon cessation of the pressure, the puncture 5 automatically closes and again seals the contents from exposure to contamination.
A frame 36 may be provided to guide the reciprocation of the container relative to the tubular shaft, and nger grip bars 38 may be provided extending radially outward from the frame. It is desirable that a plunger casing 39 besprovided to slide within the frame and carry therein the tubular container vial.
Modifications of the nipple structure for inverted syringes are shown in Figs. 6 and '7. In Fig. 6, a threaded ferrule 46 is provided so that the nipple may be threadedly engaged by a suitably threaded piston head, if desired. In Fig. 'l a nipple structure is disclosed wherein the outer face of the nipple is provided with an annular groove or recess 3n into which the edges of the piston head seat, and'thus provide for the manufacturing advantage of reducing the depth of recess 8.
In the use of the vial in apparatus acting on the syringe principle, Figs. 8 and 9 illustrate the regular type, and Fig. 10 illustrates the inverted type. Both types are adapted for use in the medical and dental professions in place of the gravity syringe or water bottle, where a large quantity of solution or paste is desired for interi' mittent use during operations lor in like situations, and a suitable conduit tube may be attached over the nipple 3.. These types of syringe dispensers are also adaptable for use in individual units or in batteries, and are especially advantageous for household and store uses where it is desired to package liquids or pastes in original closed containers and from which the contents may be dispensed in its entirety or in portions without change of container or exposure to foreign matter, and so that when a portion of the contents are dispensed, the remaining contents are not exposed to atmosphere or any contamination. Ordinarily, the containers or vials would be made in larger sizes for household and store usage than when used in an injection syringe for subcutaneous and venous injections.
In Figs. 8 and 9, the tubular container is 1, and is preferably disposed vertically, and is provided with nipple 3 and slidable closure cork 9. In Fig. 8 a supporting frame generally indicated A is provided having a top 41,` a bottom portion 42 and side wall 43, therebetween and providing a chamber whose walls are preferably fenestrated as at 44 to permit view of the container. A bracket 45 may be attached to the frame-A for mounting the syringe dispenser on a wall o'r support. A threaded plunger 46 is threadedly engaged in an opening 47 in the top and at one end engages the closure cork 9 so that as the plunger is axially rotated' in one direction by means of hand wheel 48, the closure cork 9 will be depressed to expel the contents of the container through the nipple 3, and upon being If desired. a removable dust cap 52 may be provided over the end of the nipple.
In Fig. 9 a modified form of frame and plunger .l are provided, comprising a bracket 53 mountable on a wall by suitable means, such as screws 54, and provided with a horizontally disposed annular ring container support 55, said ring preferably mounting over its upper edge and abutting its inner wall, as at 56, an annular resilient cushion 57 in which case the filling end of the container is provided with an external annular bead 58 to engage said cushion and support the container therein. A plunger frame or guide 59 is suitably mounted on the annular ring 55, pivoted at 60, and snugly fitting holes 61 inthe ring. The frame 59 has an opening 62 aligned vertically with the radial center of the annular ring 55, said opening being adapted to receive therethrough a reciprocable plunger member 63 having at one end an operating hand piece 64 and having its opposite end contacting with the closure cork 9, so that by pressure upon the plunger, the contents of the vial container l' may be discharged through the slit or puncture 5 of the nipple.
Fig. 10 is especially adapted to a syringe of the inverted type, the container vial BOand nipple 3 being of the same type shown in Fig. 5. A frame is provided, generally indicated B, which has a base 65, preferably mounted on legs 66. Extending upwardly from the base are vertical guide members l-which slidably receive and thereby guide prongs 68 of a vertically reciprocable top member 69. A tubular shaft 70 is vertically mounted on the base and is provided at its upper end with a head 71 having a recess .'72 adapted to receive therein the punctured end 5 of nipple 3, and the other end of the tube extends through an opening '73 in the base and is arranged thereat so as to support a second punctured nipple 3 preferably by a radially extending annular bead '74 over which resilient walls of the nipple may be slid and be deformed, so as to support the nipple by resilient grip. This second nipple may be further sustained in its mounting on the end of the tube by a ferrule 'l5 snugly tting around the walls thereof towhich ferrule may be mounted a conduit tube '76. Upon depression of the top 69, container 30 is depressed vertically over the tubular shaft 70 with relation to which it is slidably guided, the shaft 70 combining with the nipple to form a piston to provide pressure whereby the contents of the container are extruded through the puncture 5 into the tube 70a and through the puncture of the second nipple, the second nipple serving to prevent impurities from entering the tube 70a. Upon cessation of the pressure, the punctures ofboth nipples close by the resilience of the material thereof. l
It will be noted that the closing of the nipple by its own inherent resilience, prevents any back suction resulting from rebound of vial contents or of the resilient closure corks, upon cessation of the expelling pressure, and when used in irljection syringes, there is no drawback or suction of the contents of the needle or of blood or solution that has once been injected, nor will air be drawn into the needle during intermission between successive injections. The automatic closing of the discharge opening results in retaining the unused solution in unpoluted condition, so that it may be used in portions until the vial is entirely emptied, thus resulting in great saving of injection fluids.
The advantages of` this type of vial are apparent for purposes of sterilization. It may be placed in boiling water. without blowing out the closure members, since the expansionfrom heat is relieved by a very small amount of fluid being expelled from lthe nipple, which closes thereafter by its' own resilience.
' I claimz- 1. A container for syringe equipment including a tubular body having anopening at one end, a nipple of elastic material mounted at said open end and having a base portion providing a shoulder andhaving a tubular portion normally extended beyond the shoulder, said nipple being provided with a puncture in the extended tubular portion normally closed by the resilience of the elastic material of the nipple and adapted to open responsive to pressure within the body.
2. Acontainer for syringe equipment including a tubular body having an opening at one end, a nipple of resilient material adapted to normally close the opening of said one end portion of said tubular body, lSaid nipple having a base portion and an extended portion of less radial diameter than the base, said nipple having an axial tubular recess therein open at said base portion and having a closure wall at said extended portion, said closure wall being of lesser thickness of material than the thickness ci' material ofthe wall ysat the said base and said extended portion having a puncture therethrough, the face walls oi which are normally in contact so as to close said puncture and which are adapted to spread apart responsive to pressure within the tubular body.
3. A container for syringe equipment including a tubular body one end of which has an opening surrounded by aLange extending radially inwardly, and a nipple of elastic material adapted to normally close the opening oi said end portion of said tubular body, said nipple having a base adapted for seating on said ange within the tubular body, and having a portion extending through the opening and of lesser diameter than said base, said extended `portion being provided with a puncture therein which is normally closed responsive to the elasticity ot the nipple material, said puncture being adapted to open responsive to pressurewithin the tubular body. 4. In container equipment for extruding contents by pressure, a nipple of elastic material adapted for mounting at a portion of the container provided with an opening, comprising a base, an extension portion connected to the base .and of less diameter than the base providing a radial shoulder on the base, and providing walls of lesser thickness at the extended portion than at thebase portion, said extended portion having va Apuncture therein which is normally closed reipaaeu sponsive ,to the elasticity of the nipple material and which is adapted to open responsive to pressure within a container to which the nipple is mounted. p
5. A container for syringe equipment including a tubular body having an opening at one end, a nipple of elastic material slidably mounted within said tubular body, said nipple having .a base portion providing a shoulder and a tubular portion normally extended beyond the shoulder, said nipple being provided with a puncture in the extended tubular portion normally closed by the resilience of the elastic lmaterial of the nipple and adapted to open responsive to pressure within the body.'
6. In syringe equipment, a'closure member for an open end of a container body, comprising a nipple of elastic material having a base portion providing a shoulder and having a tubular portion normally extended axially beyond the shoulder, said nipple being provided with a puncture in the extended 'tubular portion normally closed by the resilience of the elastic material of the nipple and adapted to openresponsive to pressure within the body.
7. In syringe equipment, a `closure member for an open end of a container body. comprising a nipple of elastic material having a base portion adapted for engaging the wall of the container body 'and having a discharge end vportion comprising an axial extension from the base portion base portion is in engagement with the confor extending beyond the base portion .when the tainer wall, the base portion and the extended discharge portion being tubular and the extended discharge end portion vhaving the tube therein normally closed adjacent its extrusion end.
8. In syringe equipment, a closure member for an open end of a container body, comprising a nipple of elastic material having a base portion adapted for engaging the wall of the container body and having a discharge end portion comprising an'\axial extension from the base portion for f extending beyond the base portion when the base portion is in engagement with the container wall, the base portion and the extended discharge portion being tubular and the extended discharge end portion having the tube therein normally closed adjacent its extrusion end. the said discharge end portion including means whereby a iso-
US509958A 1931-01-20 1931-01-20 Syringe equipment and apparatus Expired - Lifetime US1929247A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US509958A US1929247A (en) 1931-01-20 1931-01-20 Syringe equipment and apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US509958A US1929247A (en) 1931-01-20 1931-01-20 Syringe equipment and apparatus

Publications (1)

Publication Number Publication Date
US1929247A true US1929247A (en) 1933-10-03

Family

ID=24028793

Family Applications (1)

Application Number Title Priority Date Filing Date
US509958A Expired - Lifetime US1929247A (en) 1931-01-20 1931-01-20 Syringe equipment and apparatus

Country Status (1)

Country Link
US (1) US1929247A (en)

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2429183A (en) * 1943-11-01 1947-10-14 Oradent Chemical Co Inc Medicament cartridge or vial
US2453589A (en) * 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe and ampoule therefor
US2453590A (en) * 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe
US2453591A (en) * 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe
US2473734A (en) * 1947-05-31 1949-06-21 Arthur E Smith Hypodermic syringe
US2537550A (en) * 1946-10-20 1951-01-09 Roos Walther Paste-dispensing syringe for medical purposes
US2538390A (en) * 1948-01-05 1951-01-16 Arthur E Smith Syringe
US2542814A (en) * 1946-10-17 1951-02-20 Sterling Drug Inc Hypodermic syringe
US2551414A (en) * 1947-11-24 1951-05-01 Lilly Co Eli Syringe
US2556331A (en) * 1946-04-01 1951-06-12 Marshall L Lockhart Tubular ampoule closure
US2568346A (en) * 1947-11-24 1951-09-18 Marshall L Lockhart Syringe structure
US2607341A (en) * 1948-12-24 1952-08-19 Frederick M Turnbull Hypodermic syringe assembly
US2610628A (en) * 1950-05-09 1952-09-16 Compule Corp Plural-compartment admixing vial for segregated storage of ingredients of solutions and liquid mixtures
US2646798A (en) * 1950-09-21 1953-07-28 Frank E Brown Cartridge syringe
US2648334A (en) * 1949-10-28 1953-08-11 Turnbull Hypodermic injection assembly
US2670121A (en) * 1951-01-31 1954-02-23 Scherer Corp R P Flexible follower for metal ampoules
US2684068A (en) * 1951-02-21 1954-07-20 Sindey R Orens Syringe
US2701565A (en) * 1953-09-14 1955-02-08 Baxter Laboratories Inc Distending plastic tube
US2705008A (en) * 1947-09-30 1955-03-29 Morton Newburger Medication cartridge-needle-needle guard unit for hypodermic syringe
US2717601A (en) * 1949-08-10 1955-09-13 Frederick M Turnbull Syringe ampule
US2737949A (en) * 1952-01-04 1956-03-13 Pfizer & Co C Disposable cartridge for hypodermic syringe
DE1049059B (en) * 1956-12-01 1959-01-22 Hoechst Ag Spray cartridge with needle stopper
US2895474A (en) * 1955-01-04 1959-07-21 Cook Waite Lab Inc Aspirating cartridge syringe
US2903794A (en) * 1956-05-07 1959-09-15 Arthur B Carfagni Amalgam carrier and dispenser
US2953243A (en) * 1957-07-25 1960-09-20 Roehr Zbislaw Maciej Disposable needle assembly
US3089490A (en) * 1960-03-14 1963-05-14 Graham Chemical Corp Disposable cartridge type hypodermic syringes
US3091240A (en) * 1958-12-29 1963-05-28 Robert K Mcconnaughey Hypodermic syringe and ventable closure means
US3207157A (en) * 1961-11-24 1965-09-21 Colin A Murdoch Means for use in the administering of drugs, medicines and the like to animals
US3845763A (en) * 1973-02-28 1974-11-05 Nasco Plastics Inc Syringe with puncturable stem
US3870044A (en) * 1971-08-13 1975-03-11 Burron Medical Prod Inc Hypodermic syringe body structure
US3941131A (en) * 1971-10-05 1976-03-02 Ims Limited Device for administration of viscous fluids for the urethal tract
US20100069786A1 (en) * 2006-06-29 2010-03-18 Depuy Spine, Inc. Integrated bone biopsy and therapy apparatus
US20100065154A1 (en) * 2006-10-19 2010-03-18 Depuy Spine, Inc. Fluid Delivery System
US8809418B2 (en) 2004-03-21 2014-08-19 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US8956368B2 (en) 2003-06-17 2015-02-17 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US8992541B2 (en) 2003-03-14 2015-03-31 DePuy Synthes Products, LLC Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US9259696B2 (en) 2005-11-22 2016-02-16 DePuy Synthes Products, Inc. Mixing apparatus having central and planetary mixing elements
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9642932B2 (en) 2006-09-14 2017-05-09 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US9839460B2 (en) 2003-03-31 2017-12-12 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US10111697B2 (en) 2003-09-26 2018-10-30 DePuy Synthes Products, Inc. Device for delivering viscous material
AU2019204338B2 (en) * 2006-10-19 2021-04-01 Depuy Spine, Inc. Fluid delivery system
US11129940B2 (en) * 2014-08-06 2021-09-28 Xeris Pharmaceuticals, Inc. Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes
US11305273B2 (en) 2017-07-27 2022-04-19 Biomerieux, Inc. Isolation tube with a rheological control member and a plunger

Cited By (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2429183A (en) * 1943-11-01 1947-10-14 Oradent Chemical Co Inc Medicament cartridge or vial
US2556331A (en) * 1946-04-01 1951-06-12 Marshall L Lockhart Tubular ampoule closure
US2542814A (en) * 1946-10-17 1951-02-20 Sterling Drug Inc Hypodermic syringe
US2537550A (en) * 1946-10-20 1951-01-09 Roos Walther Paste-dispensing syringe for medical purposes
US2453591A (en) * 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe
US2453590A (en) * 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe
US2453589A (en) * 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe and ampoule therefor
US2473734A (en) * 1947-05-31 1949-06-21 Arthur E Smith Hypodermic syringe
US2705008A (en) * 1947-09-30 1955-03-29 Morton Newburger Medication cartridge-needle-needle guard unit for hypodermic syringe
US2551414A (en) * 1947-11-24 1951-05-01 Lilly Co Eli Syringe
US2568346A (en) * 1947-11-24 1951-09-18 Marshall L Lockhart Syringe structure
US2538390A (en) * 1948-01-05 1951-01-16 Arthur E Smith Syringe
US2607341A (en) * 1948-12-24 1952-08-19 Frederick M Turnbull Hypodermic syringe assembly
US2717601A (en) * 1949-08-10 1955-09-13 Frederick M Turnbull Syringe ampule
US2648334A (en) * 1949-10-28 1953-08-11 Turnbull Hypodermic injection assembly
US2610628A (en) * 1950-05-09 1952-09-16 Compule Corp Plural-compartment admixing vial for segregated storage of ingredients of solutions and liquid mixtures
US2646798A (en) * 1950-09-21 1953-07-28 Frank E Brown Cartridge syringe
US2670121A (en) * 1951-01-31 1954-02-23 Scherer Corp R P Flexible follower for metal ampoules
US2684068A (en) * 1951-02-21 1954-07-20 Sindey R Orens Syringe
US2737949A (en) * 1952-01-04 1956-03-13 Pfizer & Co C Disposable cartridge for hypodermic syringe
US2701565A (en) * 1953-09-14 1955-02-08 Baxter Laboratories Inc Distending plastic tube
US2895474A (en) * 1955-01-04 1959-07-21 Cook Waite Lab Inc Aspirating cartridge syringe
US2903794A (en) * 1956-05-07 1959-09-15 Arthur B Carfagni Amalgam carrier and dispenser
DE1049059B (en) * 1956-12-01 1959-01-22 Hoechst Ag Spray cartridge with needle stopper
US2953243A (en) * 1957-07-25 1960-09-20 Roehr Zbislaw Maciej Disposable needle assembly
US3091240A (en) * 1958-12-29 1963-05-28 Robert K Mcconnaughey Hypodermic syringe and ventable closure means
US3089490A (en) * 1960-03-14 1963-05-14 Graham Chemical Corp Disposable cartridge type hypodermic syringes
US3207157A (en) * 1961-11-24 1965-09-21 Colin A Murdoch Means for use in the administering of drugs, medicines and the like to animals
US3870044A (en) * 1971-08-13 1975-03-11 Burron Medical Prod Inc Hypodermic syringe body structure
US3941131A (en) * 1971-10-05 1976-03-02 Ims Limited Device for administration of viscous fluids for the urethal tract
US3845763A (en) * 1973-02-28 1974-11-05 Nasco Plastics Inc Syringe with puncturable stem
US10799278B2 (en) 2003-03-14 2020-10-13 DePuy Synthes Products, Inc. Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US8992541B2 (en) 2003-03-14 2015-03-31 DePuy Synthes Products, LLC Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US9186194B2 (en) 2003-03-14 2015-11-17 DePuy Synthes Products, Inc. Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US10485597B2 (en) 2003-03-31 2019-11-26 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US9839460B2 (en) 2003-03-31 2017-12-12 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US10039585B2 (en) 2003-06-17 2018-08-07 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US8956368B2 (en) 2003-06-17 2015-02-17 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US9504508B2 (en) 2003-06-17 2016-11-29 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US10111697B2 (en) 2003-09-26 2018-10-30 DePuy Synthes Products, Inc. Device for delivering viscous material
US9750840B2 (en) 2004-03-21 2017-09-05 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US8809418B2 (en) 2004-03-21 2014-08-19 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US9259696B2 (en) 2005-11-22 2016-02-16 DePuy Synthes Products, Inc. Mixing apparatus having central and planetary mixing elements
US10631906B2 (en) 2005-11-22 2020-04-28 DePuy Synthes Products, Inc. Apparatus for transferring a viscous material
US20100069786A1 (en) * 2006-06-29 2010-03-18 Depuy Spine, Inc. Integrated bone biopsy and therapy apparatus
US10272174B2 (en) 2006-09-14 2019-04-30 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US9642932B2 (en) 2006-09-14 2017-05-09 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US10494158B2 (en) * 2006-10-19 2019-12-03 DePuy Synthes Products, Inc. Fluid delivery system
US20100065154A1 (en) * 2006-10-19 2010-03-18 Depuy Spine, Inc. Fluid Delivery System
US8950929B2 (en) 2006-10-19 2015-02-10 DePuy Synthes Products, LLC Fluid delivery system
AU2019204338B2 (en) * 2006-10-19 2021-04-01 Depuy Spine, Inc. Fluid delivery system
US11129940B2 (en) * 2014-08-06 2021-09-28 Xeris Pharmaceuticals, Inc. Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes
US11305273B2 (en) 2017-07-27 2022-04-19 Biomerieux, Inc. Isolation tube with a rheological control member and a plunger
US11325117B2 (en) 2017-07-27 2022-05-10 Biomerieux, Inc. Centrifugally separating samples in a container having a seal and containing a plunger for opening the seal
US11383231B2 (en) 2017-07-27 2022-07-12 Biomerieux, Inc. Isolation tube
US11440000B2 (en) * 2017-07-27 2022-09-13 Biomerieux, Inc. Isolation tube with an endcap
US11850584B2 (en) 2017-07-27 2023-12-26 Biomerieux, Inc. Isolation tube
US11883818B2 (en) 2017-07-27 2024-01-30 Biomerieux, Inc. Isolation tube
US11918998B2 (en) 2017-07-27 2024-03-05 BIOMéRIEUX, INC. Assembly comprising a sample collection vessel and a separation container having seal, plunger with seal-piercing point, retainer, and flexible sealing member

Similar Documents

Publication Publication Date Title
US1929247A (en) Syringe equipment and apparatus
US3853157A (en) Process and apparatus for dispensing liquid compositions intended for parenteral administration
US2514575A (en) Introversion syringe
US2764979A (en) Medicament dispensing unit
US2599446A (en) Resilient walled supply container with connected measuring trap chamber
US3458090A (en) Fluid dispenser with adjustable stroke pump piston
US2764157A (en) Ampules
US4236516A (en) Syringe and disposable container therefor
US2020828A (en) Hypodermic syringe and closure cap for containers
US2314167A (en) Parenteral injection device
US3110309A (en) Plastic cartridge needle assembly
US2653611A (en) Closure
US2239275A (en) Self-contained liquid dispensing device
US3369708A (en) Means for reconstituting a dry biological and for controlled dispensing thereof
US2690278A (en) Dispensing pump for small containers
US3841329A (en) Compact syringe
US3091240A (en) Hypodermic syringe and ventable closure means
US2689564A (en) Blood donor assembly
US2787268A (en) Blood plasma bottle
US2954769A (en) Aseptic liquid transfer apparatus
US3820576A (en) Pipette stopper
JP5437510B1 (en) Two-chamber syringe
US2768623A (en) Container for liquids, and more particularly to a container which incorporates therein the function of a syringe
US1949058A (en) Dispensing bottle stopper
US1563627A (en) Syringe ampul, piston, and piston-packing construction