US1189465A - Container for hypodermic solutions. - Google Patents

Container for hypodermic solutions. Download PDF

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Publication number
US1189465A
US1189465A US7385316A US7385316A US1189465A US 1189465 A US1189465 A US 1189465A US 7385316 A US7385316 A US 7385316A US 7385316 A US7385316 A US 7385316A US 1189465 A US1189465 A US 1189465A
Authority
US
United States
Prior art keywords
container
disk
hypodermic
cap
needle
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US7385316A
Inventor
Nelson S Mayo
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Abbott Laboratories
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Abbott Laboratories
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Priority to US7385316A priority Critical patent/US1189465A/en
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Publication of US1189465A publication Critical patent/US1189465A/en
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Expired - Lifetime legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/03Medical

Definitions

  • CONTAINER FOR HYPODEBMIC SOLUTIONS/' I lar instrument maybe inserted through the closure into the container for the purpose of withdrawing. the solution.
  • a sealed container for hypodermic 0r analogous fluids so arranged that the pointof a hypodermic needle or analogous instrument may be readily inserted into the fluid for the purpose of withdrawingit from the container uncontaminated by exterior agencies, while at the same time sterilizing the instrument which is inserted Y into the container;
  • a container of the class described provided with a supplyof antiseptic material which is maintained out of contact with the solution in the container and which therefore does not tend to neutralize or in any way affect the potency of the hypodermic solution;
  • a closure of the class described which is capable of being readily pierced by the point of a hypodermic needle or other instrument in order to insert the same into the solution Specification of Letters'Patent.
  • Figure 1 is an axial section through a container constructed according -,to my invention
  • Fig. 2 is a plan view of the container ,shown in Fig. 1, the protective outer cap havin been removed
  • Fig. 3 is a section similar to Fig. '1, the external thimble having been removed to permit the insertion of a hypodermic needle into the-solution.
  • the container 10 is in this instance a bottle'made of glass or other material having the required aseptic properties.
  • the particular container shown and described is substantially cylindrical in shape and the closure therefor is applied to the reduced substantially cylindrical neck '11, in this instance slightly less in diameter than the diameter of the body of the container.
  • the outside of the neck 11 is threaded to accommodate a screw cap 12 rial, said cap being provided with one or more perforations 13, as shown in Fig. 2.
  • the cap 14 is a disk of sealing material, such as soft rubber, which is impervious to the hypodermic liquid 15 contained within the glass receptacle 10, and constitutes the hermetic seal for the mouth of the container.
  • a disk 16 of porous material for instance sponge rubber, which is charged with a disinfectant such as a carbolic acid solution or suitable germicide.
  • a disinfectant such as a carbolic acid solution or suitable germicide.
  • the sealing disk 14 is first placed over the mouth of the container,-and afterward the antispetic disk 16 and the subsidiary sealing disk 17 are placed in position over the primary sealing disk 14. .
  • the screw cap 12 is then screwed down into the position shown in Figs. 1 and 2, thereby compressing all three disks, this accomplishin two main objects;first, the sealing dis '14 is thrust tightly against the open mouth of the container, thereby sealing the same against contaminating agencies; and secondly, the disk 17 is pressed tightly up against the top of the cap and so seals the perforations and prevents the antispetic contained in the disk 16 from being lost or wasted.
  • the disk 14 is sufiiciently compressed to force its outer edge substantially into engagement with the interior circumference of the cap 12, which prevents leakage of the antiseptic past the threads of the fn order to withdraw a charge of the contained solution by means of a hypodermic syringe or needle, the nose or point 18 of the needle is thrust forcibly through one of the apertures 13 until it passes through all three of the rubber disks and enters the solution a sufiicient distance to permit the withdrawal of the proper amount of the fluid therein. After the mechanism of the needle has been properly manipulated to draw up the required charge of fluid, the nose of the syringe is Withdrawn.
  • the container 10 may be of sufficient capacity to receive quite a number of hypodermic doses or injections, and a succession of antiseptic charges of fluid may be successively removed from the container in the above described manner without destroying the hermetically sealed character of the receptacle ,closure. This end is attained by making the sealing disk 14 of soft rubber so thatwhen the point of the needle is withdrawn the edges of the hole in the disk 14 will immediately close up and restore the seal to practically its original efliciency.
  • the top of the cap 12 has several perforations so that the antiseptic or disinfectant contained in the pores of the disk 16 may be utilized over a wide area and so prevent the possibility of the needle being improperly sterilized if thrust through the same spot in the closure several times after the disinfectant around that particular spot has become exhausted.
  • I claim 1 In a container for hypodermic solutions having an outwardly facing sealing mouth, the combination of a readily perforable member of porous rubber charged With a germicidal material, a seal of flexible rubber interposed between said mouth and said readily perforableporous rubber memher, a member secured to said container and constituting a cap for said porous rubber member and said flexible rubber seal, said cap having a perforation therein for the insertion of a hypodermic needle for Withdrawing a charge of the solution from the container, and a secondary seal offlexible rubber adapted to cover said porous rubber member, the said cap serving as an inchsure for said seals and said porous rubber member and as a means for forcing them toward said sealing mouth and for pressing said first mentioned seal against said sealing mouth whereby the evaporation of the germicide in said porous rubber member is prevented.
  • a container having a sealing mouth and a threaded neck surrounding said mouth, a porous readily perforable disk charged with a germicidal material and covering said mouth, a sealing disk of flexible rubber interposed between said mouth and said porous disk, a cap threaded on said neck having its outer. end perforated to admit a hypodermic needle and adapted to press said disks, and a disk of flexible rubber interposed between said porous disk and 5 said cap, said flexible disks constituting with the cap a sealed inclosure for said porous element to prevent evaporation of the germicidal material.

Description

N. S. MAYO.
CONTAINER FOR HYRODERMIC SOLUTIONS.
APPLICATION FILED JAN.24. l9l6.
Patented July 4, 1916.
.UNITED STATES PATENT OFFICE.
NELSON S. MAYO, OF CHICAGO, ILLINOIS, ASSIGNOB TO THE ABBOTT LABORATORIES,
OF CHICAGO, ILLINOIS, A CORPORATION OF ILLINOIS.
CONTAINER FOR HYPODEBMIC SOLUTIONS/' I lar instrument maybe inserted through the closure into the container for the purpose of withdrawing. the solution.
It will be readily understood by all persons skilled in the arts of medicine and surgery that points of hypodermic needles or analogous instruments must be maintained in absolute antiseptic condition if they are to be used without danger of infecting the patient. It is also clear that solutions such as vaccine, antitoxin, or other medicinal or sur "cal liri uids which are to be injected hypo ermica ly must be kept absolutely uncontaminated by foreign agencies; other-.
wise, the solution when injected hypodermically will of itself cause infection.
Among the salient objects of my invention are, to provide a sealed container for hypodermic 0r analogous fluids, so arranged that the pointof a hypodermic needle or analogous instrument may be readily inserted into the fluid for the purpose of withdrawingit from the container uncontaminated by exterior agencies, while at the same time sterilizing the instrument which is inserted Y into the container; to provide .a container of the class described provided with a supplyof antiseptic material which is maintained out of contact with the solution in the container and which therefore does not tend to neutralize or in any way affect the potency of the hypodermic solution; to provide a closure for a container of the class described such that the antiseptic material is maintained sealed against the atmosphere, thereby preserving the antiseptic character of the closurefor an indefinite period; to provide a closure of the class described which is capable of being readily pierced by the point of a hypodermic needle or other instrument in order to insert the same into the solution Specification of Letters'Patent.
which,-
made of aluminum or other suitable mate- Patented July 4, 1916.
Application filed January 2 4, 1916. Serial No. 73,853.
container; to provide a closure of the type last described and of such character as to admit of its being pierced by a hypodermic needle and upon the removal of the needle w1ll at once assume its normal function as a seal for the container; to provide a closure of the class described, the efliciency of which 1s not seriously impaired by a single insert1on of the hypodermic. needle but which will permit the insertion of the needle several times before the antiseptic characterlfifin or of the seal is destroyed;-to provide a container and closure therefor of the class described of simple design and economical to manufacture, and,-'.in general, to provide an improved construction of the character re ferred to. v
Myinvention willbe readily understood when this description is considered in connection with the accompanying drawings, in
Figure 1 is an axial section through a container constructed according -,to my invention; Fig. 2 is a plan view of the container ,shown in Fig. 1, the protective outer cap havin been removed; and Fig. 3 is a section similar to Fig. '1, the external thimble having been removed to permit the insertion of a hypodermic needle into the-solution.
Referring to thedrawings, the container 10 is in this instance a bottle'made of glass or other material having the required aseptic properties. The particular container shown and described is substantially cylindrical in shape and the closure therefor is applied to the reduced substantially cylindrical neck '11, in this instance slightly less in diameter than the diameter of the body of the container. The outside of the neck 11 is threaded to accommodate a screw cap 12 rial, said cap being provided with one or more perforations 13, as shown in Fig. 2.
14 is a disk of sealing material, such as soft rubber, which is impervious to the hypodermic liquid 15 contained within the glass receptacle 10, and constitutes the hermetic seal for the mouth of the container. Between the rubber sealing disk 14 and the v perforated top of. the cap 121 interpose a disk 16 of porous material, for instance sponge rubber, which is charged with a disinfectant such as a carbolic acid solution or suitable germicide. In order to prevent the sponge rubber 16 and escaping through the perforations 13 in the top of the cap 12,
there is inserted between the perforated top of the cap 12 and the antiseptic disk 16 a second disk 17 of impervious sealing material, similar to the disk 14.
In practice, after the serum or other hypodermic solution has been initially introduced into the previously sterilized receptacle 10, the sealing disk 14 is first placed over the mouth of the container,-and afterward the antispetic disk 16 and the subsidiary sealing disk 17 are placed in position over the primary sealing disk 14. .The screw cap 12 is then screwed down into the position shown in Figs. 1 and 2, thereby compressing all three disks, this accomplishin two main objects;first, the sealing dis '14 is thrust tightly against the open mouth of the container, thereby sealing the same against contaminating agencies; and secondly, the disk 17 is pressed tightly up against the top of the cap and so seals the perforations and prevents the antispetic contained in the disk 16 from being lost or wasted. It will be observed that the disk 14 is sufiiciently compressed to force its outer edge substantially into engagement with the interior circumference of the cap 12, which prevents leakage of the antiseptic past the threads of the fn order to withdraw a charge of the contained solution by means of a hypodermic syringe or needle, the nose or point 18 of the needle is thrust forcibly through one of the apertures 13 until it passes through all three of the rubber disks and enters the solution a sufiicient distance to permit the withdrawal of the proper amount of the fluid therein. After the mechanism of the needle has been properly manipulated to draw up the required charge of fluid, the nose of the syringe is Withdrawn. It will be manifest that the effect of pushing the point or nose of the needle through the antiseptic member 16 will be to completely sterilize the point of the needle and such part of its length as comes in contact with the disinfectant contained within the pores of the antiseptic disk. Also, owing to the fact that it has been unnecessary to remove the cap 12 and the sealing disk 14 from the container, the fluid therein contained is uncontaminated by outside agencies and retains its original properties. The container 10 may be of sufficient capacity to receive quite a number of hypodermic doses or injections, and a succession of antiseptic charges of fluid may be successively removed from the container in the above described manner without destroying the hermetically sealed character of the receptacle ,closure. This end is attained by making the sealing disk 14 of soft rubber so thatwhen the point of the needle is withdrawn the edges of the hole in the disk 14 will immediately close up and restore the seal to practically its original efliciency.
The top of the cap 12 has several perforations so that the antiseptic or disinfectant contained in the pores of the disk 16 may be utilized over a wide area and so prevent the possibility of the needle being improperly sterilized if thrust through the same spot in the closure several times after the disinfectant around that particular spot has become exhausted. As an additional precaution and to prevent foreign matter or infection from gathering on the top of the closure and coming in contact with the needle, I place over the ca 12 an external thimble 19 which is unper orated and furnished with a thin disk 20 of absorbent material such as cloth which is charged with a disinfectant such as carbolic acid. With this arrangement the possibility of infecting the needle or the hypodermic solution is reduced to a negligible item.
Although I have described in this specification a single application of my invention, which I consider a preferred embodiment, it should be understood that time and experience may indicate that the invention may be embodied in various other forms suited for a variety of needs.
Hence, the scope of the invention is to be determined, not by reference to the described details of construction or operation, but by reference tothe appended claims.
I claim 1. In a container for hypodermic solutions having an outwardly facing sealing mouth, the combination of a readily perforable member of porous rubber charged With a germicidal material, a seal of flexible rubber interposed between said mouth and said readily perforableporous rubber memher, a member secured to said container and constituting a cap for said porous rubber member and said flexible rubber seal, said cap having a perforation therein for the insertion of a hypodermic needle for Withdrawing a charge of the solution from the container, and a secondary seal offlexible rubber adapted to cover said porous rubber member, the said cap serving as an inchsure for said seals and said porous rubber member and as a means for forcing them toward said sealing mouth and for pressing said first mentioned seal against said sealing mouth whereby the evaporation of the germicide in said porous rubber member is prevented.
2. A container having a sealing mouth and a threaded neck surrounding said mouth, a porous readily perforable disk charged with a germicidal material and covering said mouth, a sealing disk of flexible rubber interposed between said mouth and said porous disk, a cap threaded on said neck having its outer. end perforated to admit a hypodermic needle and adapted to press said disks, and a disk of flexible rubber interposed between said porous disk and 5 said cap, said flexible disks constituting with the cap a sealed inclosure for said porous element to prevent evaporation of the germicidal material.
"3. The combination of a container for hygodermic solutions provided with a neck 10 an a sealing orifice, a rubber sealing disk fitting over said orifice, a porous member charged with germicidal material overlying said disk, a subsidiary sealing disk overlying said porous element, and a perforated 15 screw cap inclosing said disks threaded onto said neck for making said seals eflective. NELSON S. MAYO.
US7385316A 1916-01-24 1916-01-24 Container for hypodermic solutions. Expired - Lifetime US1189465A (en)

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Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2680531A (en) * 1951-05-28 1954-06-08 West Co Cap structure for bottles
US2804224A (en) * 1954-04-15 1957-08-27 Mead Johnson & Co Blood bottle closure
US2961959A (en) * 1956-10-01 1960-11-29 Gen Electric Torpedo actuating lanyard seal
US3424329A (en) * 1967-06-21 1969-01-28 Schering Corp Sealed injection vial
US4444329A (en) * 1982-09-29 1984-04-24 Vollers Gary L Container cap and seal formation of indicia
US4524809A (en) * 1983-01-29 1985-06-25 Sterimatic Holdings Limited Fitments for containers from which liquid is intended to be withdrawn by a hollow needle or tube
WO1986006708A1 (en) * 1985-05-17 1986-11-20 J.C. Schumacher Company Septum closure
US4671331A (en) * 1986-03-13 1987-06-09 Lyphomed, Inc. Cover for medicinal vial
US4700202A (en) * 1983-02-23 1987-10-13 Sharp Kabushiki Kaisha Ink cartridge in an ink jet system printer
US4815619A (en) * 1987-07-13 1989-03-28 Turner Thomas R Medicament vial safety cap
US4886178A (en) * 1988-04-27 1989-12-12 Air Products And Chemicals, Inc. Method and apparatus for packaging, shipping and using poisonous liquids
US5014869A (en) * 1990-03-26 1991-05-14 Hammond David W Sanitary can seal organization
US5061263A (en) * 1989-02-13 1991-10-29 Terumo Kabushiki Kaisha Liquid collection tube
US5637107A (en) * 1994-12-29 1997-06-10 Vaillancourt; Vincent L. Sterilized vial closure and a sterilized parenteral vial
US6544246B1 (en) * 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
US20060030832A1 (en) * 2000-01-24 2006-02-09 Bracco Diagnostics, Inc. Tabletop drug dispensing vial access adapter
US20070032775A1 (en) * 2000-01-24 2007-02-08 Bracco Diagnostics, Inc. Tabletop drug dispensing vial access adapter
US20090178998A1 (en) * 2007-12-31 2009-07-16 Keisha Gay Knight Closed cover for medicinal vial
KR20100040887A (en) * 2007-06-29 2010-04-21 메르크 파텐트 게엠베하 Closure with membrane and rotatable protective cap
US20130053815A1 (en) * 2011-08-23 2013-02-28 Allergan, Inc. High recovery vial adaptor
US20130174937A1 (en) * 2011-07-26 2013-07-11 Hainan Weikang Pharmaceutical (Qianshan) Co.,Ltd Puncture Free Bottle Cork and the Application Thereof
USD763691S1 (en) 2014-11-13 2016-08-16 Cornerstone Cm, Inc. Cap for a bottle
USD764920S1 (en) 2014-11-13 2016-08-30 Cornerstone Cm, Inc. Bottle
US9505599B2 (en) 2014-11-13 2016-11-29 Cornerstone Cm, Inc. Evacuated bottle system
US9517922B2 (en) 2014-11-13 2016-12-13 Cornerstone Cm, Inc. Evacuated bottle system
USD859986S1 (en) 2014-11-13 2019-09-17 Cornerstone Cm, Inc. Stopper for bottle
US11230421B2 (en) 2014-11-13 2022-01-25 Cscm Management Company Llc Evacuated bottle system

Cited By (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2680531A (en) * 1951-05-28 1954-06-08 West Co Cap structure for bottles
US2804224A (en) * 1954-04-15 1957-08-27 Mead Johnson & Co Blood bottle closure
US2961959A (en) * 1956-10-01 1960-11-29 Gen Electric Torpedo actuating lanyard seal
US3424329A (en) * 1967-06-21 1969-01-28 Schering Corp Sealed injection vial
US4444329A (en) * 1982-09-29 1984-04-24 Vollers Gary L Container cap and seal formation of indicia
US4524809A (en) * 1983-01-29 1985-06-25 Sterimatic Holdings Limited Fitments for containers from which liquid is intended to be withdrawn by a hollow needle or tube
US4700202A (en) * 1983-02-23 1987-10-13 Sharp Kabushiki Kaisha Ink cartridge in an ink jet system printer
WO1986006708A1 (en) * 1985-05-17 1986-11-20 J.C. Schumacher Company Septum closure
US4671331A (en) * 1986-03-13 1987-06-09 Lyphomed, Inc. Cover for medicinal vial
US4815619A (en) * 1987-07-13 1989-03-28 Turner Thomas R Medicament vial safety cap
US4886178A (en) * 1988-04-27 1989-12-12 Air Products And Chemicals, Inc. Method and apparatus for packaging, shipping and using poisonous liquids
US5061263A (en) * 1989-02-13 1991-10-29 Terumo Kabushiki Kaisha Liquid collection tube
US5014869A (en) * 1990-03-26 1991-05-14 Hammond David W Sanitary can seal organization
US5637107A (en) * 1994-12-29 1997-06-10 Vaillancourt; Vincent L. Sterilized vial closure and a sterilized parenteral vial
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6544246B1 (en) * 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
US20060030832A1 (en) * 2000-01-24 2006-02-09 Bracco Diagnostics, Inc. Tabletop drug dispensing vial access adapter
US20070032775A1 (en) * 2000-01-24 2007-02-08 Bracco Diagnostics, Inc. Tabletop drug dispensing vial access adapter
US8409165B2 (en) 2000-01-24 2013-04-02 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US20100298805A1 (en) * 2000-01-24 2010-11-25 Bracco Diagnostics Inc. Tabletop Drug Dispensing Vial Access Adapter
KR20100040887A (en) * 2007-06-29 2010-04-21 메르크 파텐트 게엠베하 Closure with membrane and rotatable protective cap
JP2010531781A (en) * 2007-06-29 2010-09-30 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Sealing device with membrane and rotatable protective cap
US20100176080A1 (en) * 2007-06-29 2010-07-15 Merck Patent Gesellschaft Closure with membrane and rotatable protective cap
US10160576B2 (en) * 2007-06-29 2018-12-25 Merck Patent Gmbh Closure with membrane and rotatable protective cap
KR101603348B1 (en) * 2007-06-29 2016-03-14 메르크 파텐트 게엠베하 Closure with membrane and rotatable protective cap
US20090178998A1 (en) * 2007-12-31 2009-07-16 Keisha Gay Knight Closed cover for medicinal vial
US20130174937A1 (en) * 2011-07-26 2013-07-11 Hainan Weikang Pharmaceutical (Qianshan) Co.,Ltd Puncture Free Bottle Cork and the Application Thereof
US20130053815A1 (en) * 2011-08-23 2013-02-28 Allergan, Inc. High recovery vial adaptor
US20160151241A1 (en) * 2011-08-23 2016-06-02 Allergan, Inc. High recovery vial adaptor
USD859986S1 (en) 2014-11-13 2019-09-17 Cornerstone Cm, Inc. Stopper for bottle
USD946400S1 (en) 2014-11-13 2022-03-22 Cscm Management Company Llc Funnel
US9517922B2 (en) 2014-11-13 2016-12-13 Cornerstone Cm, Inc. Evacuated bottle system
USD805899S1 (en) 2014-11-13 2017-12-26 Cornerstone Cm, Inc. Stopper for bottle
USD809923S1 (en) 2014-11-13 2018-02-13 Cornerstone Cm, Inc. Bottle
US10017315B2 (en) 2014-11-13 2018-07-10 Cornerstone C.M, Inc. Evacuated bottle system
US10106308B2 (en) 2014-11-13 2018-10-23 Cornerstone C.M., Inc. Evacuated bottle system
USD764920S1 (en) 2014-11-13 2016-08-30 Cornerstone Cm, Inc. Bottle
US10252851B2 (en) 2014-11-13 2019-04-09 Cornerstone Cm, Inc. Evacuated bottle system
US10308415B2 (en) 2014-11-13 2019-06-04 Cornerstone Cm, Inc. Evacuated bottle system
USD976705S1 (en) 2014-11-13 2023-01-31 Cscm Management Company Llc Cap for a bottle
US9505599B2 (en) 2014-11-13 2016-11-29 Cornerstone Cm, Inc. Evacuated bottle system
USD908486S1 (en) 2014-11-13 2021-01-26 Cornerstone Cm, Inc. Stopper for bottle
US10858168B2 (en) 2014-11-13 2020-12-08 Cornerstone Cm, Inc. Evacuated bottle system
US10836556B2 (en) 2014-11-13 2020-11-17 Cornerstone Cm, Inc. Evacuated bottle system
US10961039B2 (en) 2014-11-13 2021-03-30 Cornerstone Cm, Inc Evacuated bottle system
USD920796S1 (en) 2014-11-13 2021-06-01 Cornerstone Cm, Inc. Bottle
USD926572S1 (en) 2014-11-13 2021-08-03 Cornerstone Cm, Inc. Stopper for bottle
US11230421B2 (en) 2014-11-13 2022-01-25 Cscm Management Company Llc Evacuated bottle system
US11242185B2 (en) 2014-11-13 2022-02-08 Cscm Management Company Llc Evacuated bottle system
US11254484B2 (en) 2014-11-13 2022-02-22 Cscm Management Company Llc Evacuated bottle system
USD871220S1 (en) 2014-11-13 2019-12-31 Cornerstone Cm, Inc. Bottle
US11560267B2 (en) 2014-11-13 2023-01-24 Cscm Management Company Llc Evacuated bottle system
USD763691S1 (en) 2014-11-13 2016-08-16 Cornerstone Cm, Inc. Cap for a bottle

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