EP2150243A4 - Compositions and methods for enhancing active agent absorption - Google Patents

Compositions and methods for enhancing active agent absorption

Info

Publication number
EP2150243A4
EP2150243A4 EP08755962.1A EP08755962A EP2150243A4 EP 2150243 A4 EP2150243 A4 EP 2150243A4 EP 08755962 A EP08755962 A EP 08755962A EP 2150243 A4 EP2150243 A4 EP 2150243A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
active agent
agent absorption
enhancing active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08755962.1A
Other languages
German (de)
French (fr)
Other versions
EP2150243A2 (en
Inventor
Chung Shih
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NexusPharma Inc
Original Assignee
NexusPharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/805,202 external-priority patent/US8426466B2/en
Application filed by NexusPharma Inc filed Critical NexusPharma Inc
Publication of EP2150243A2 publication Critical patent/EP2150243A2/en
Publication of EP2150243A4 publication Critical patent/EP2150243A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
EP08755962.1A 2007-05-21 2008-05-20 Compositions and methods for enhancing active agent absorption Withdrawn EP2150243A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/805,202 US8426466B2 (en) 2006-05-22 2007-05-21 Compositions and methods for enhancing active agent absorption
US409907P 2007-11-21 2007-11-21
PCT/US2008/064233 WO2008144690A2 (en) 2007-05-21 2008-05-20 Compositions and methods for enhancing active agent absorption

Publications (2)

Publication Number Publication Date
EP2150243A2 EP2150243A2 (en) 2010-02-10
EP2150243A4 true EP2150243A4 (en) 2013-08-21

Family

ID=40122287

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08755962.1A Withdrawn EP2150243A4 (en) 2007-05-21 2008-05-20 Compositions and methods for enhancing active agent absorption

Country Status (2)

Country Link
EP (1) EP2150243A4 (en)
WO (1) WO2008144690A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906592B (en) * 2011-02-25 2017-11-03 广州南沙龙沙有限公司 Side chain connected body for pharmaceutical grade protein conjugate
EP3031905A4 (en) * 2013-08-07 2017-04-26 Kyoto University Method for producing pancreatic hormone-producing cell

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817624A (en) * 1995-06-05 1998-10-06 Alza Corporation Permeation enhancer compositions for increased absorption of therapeutic proteins through the colonic membrane
EP1250056B1 (en) * 2000-01-27 2006-08-30 Peros Systèmes Technologies Inc. Composition for intestinal delivery
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
CN100522243C (en) * 2006-03-13 2009-08-05 新疆维吾尔自治区畜牧科学院兽医研究所 Animal skin penetrant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FAUST JOHN A ET AL: "Derivatives of salicylamide", AMERICAN PHARMACEUTICAL ASSOCIATION. JOURNAL, AMERICAN PHARMACISTS ASSOCIATION, US, vol. 45, no. 8, 20 February 1956 (1956-02-20), pages 514 - 517, XP008115755, ISSN: 0003-0465, [retrieved on 20060923], DOI: 10.1002/JPS.3030450803 *
NAITO MASUKAZU ET AL: "Chemotherapeutics for Mycobacterium tuberculosis. XII. Antibacterial activity of derivatives of esters of p-aminosalicylic acid on Mycobacterium tuberculosis", YAKUGAKU ZASSHI, PHARMACEUTICAL SOCIETY OF JAPAN, JP, vol. 78, no. 6, 1 January 1958 (1958-01-01), pages 682 - 683, XP008115756, ISSN: 0031-6903 *
See also references of WO2008144690A2 *
XUAN DING ET AL: "Oral Absorption Enhancement of Cromolyn Sodium Through Noncovalent Complexation", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 21, no. 12, 1 December 2004 (2004-12-01), pages 2196 - 2206, XP019370659, ISSN: 1573-904X, DOI: 10.1007/S11095-004-7671-9 *

Also Published As

Publication number Publication date
WO2008144690A3 (en) 2009-02-26
EP2150243A2 (en) 2010-02-10
WO2008144690A2 (en) 2008-11-27

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Legal Events

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Effective date: 20130724

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 47/10 20060101ALI20130718BHEP

Ipc: A61K 9/00 20060101ALI20130718BHEP

Ipc: A61K 38/16 20060101AFI20130718BHEP

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Ipc: A61K 31/715 20060101ALI20130718BHEP

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