EP1852109A4 - Xylitol granules capable of directly being pressed into tablets and preparation process thereof - Google Patents

Xylitol granules capable of directly being pressed into tablets and preparation process thereof

Info

Publication number
EP1852109A4
EP1852109A4 EP06741800A EP06741800A EP1852109A4 EP 1852109 A4 EP1852109 A4 EP 1852109A4 EP 06741800 A EP06741800 A EP 06741800A EP 06741800 A EP06741800 A EP 06741800A EP 1852109 A4 EP1852109 A4 EP 1852109A4
Authority
EP
European Patent Office
Prior art keywords
tablets
pressed
directly
preparation process
granules capable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06741800A
Other languages
German (de)
French (fr)
Other versions
EP1852109A1 (en
Inventor
Li Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEIJING JIANLI PHARMACEUTICAL Co Ltd
BEIJING JIANLI PHARMACEUTICAL
Original Assignee
BEIJING JIANLI PHARMACEUTICAL Co Ltd
BEIJING JIANLI PHARMACEUTICAL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BEIJING JIANLI PHARMACEUTICAL Co Ltd, BEIJING JIANLI PHARMACEUTICAL filed Critical BEIJING JIANLI PHARMACEUTICAL Co Ltd
Publication of EP1852109A1 publication Critical patent/EP1852109A1/en
Publication of EP1852109A4 publication Critical patent/EP1852109A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/34—Sugar alcohols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/37—Sugar alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
EP06741800A 2005-05-08 2006-05-08 Xylitol granules capable of directly being pressed into tablets and preparation process thereof Withdrawn EP1852109A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2005100682552A CN1686089B (en) 2005-05-08 2005-05-08 Xylitol granule capable of directly being pressed into tablet and its preparation method
PCT/CN2006/000905 WO2006119697A1 (en) 2005-05-08 2006-05-08 Xylitol granules capable of directly being pressed into tablets and preparation process thereof

Publications (2)

Publication Number Publication Date
EP1852109A1 EP1852109A1 (en) 2007-11-07
EP1852109A4 true EP1852109A4 (en) 2010-05-12

Family

ID=35304130

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06741800A Withdrawn EP1852109A4 (en) 2005-05-08 2006-05-08 Xylitol granules capable of directly being pressed into tablets and preparation process thereof

Country Status (4)

Country Link
US (1) US20080161417A1 (en)
EP (1) EP1852109A4 (en)
CN (1) CN1686089B (en)
WO (1) WO2006119697A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1903056B (en) * 2006-08-01 2010-12-08 北京健健康康生物技术有限公司 Xylitox coffee products for chewing or instant dissolving, and its prepn. method
WO2008052426A1 (en) * 2006-11-03 2008-05-08 Anhui Fukang Pharmaceutical Co., Ltd A xylitol candy tablet and preparation method thereof
CN101283776A (en) * 2007-04-11 2008-10-15 欧劳福林精细化工（昆山）有限公司 Granular sweetener
CN101897671B (en) * 2009-05-25 2012-11-14 范敏华 Xylitol micro pill preparations and preparation method thereof
IT1396118B1 (en) * 2009-09-23 2012-11-16 Eridania Sadam S P A SWEETENING COMPOSITION.
CN103415284B (en) * 2011-03-09 2016-12-07 巴斯夫欧洲公司 Pharmaceutical formulation for producing rapidly disintegrating tablets
CN102429885B (en) * 2011-12-30 2013-05-08 山东力诺科峰制药有限公司 DC (Directly compressible)-xylitol and preparation method thereof
CN103099210B (en) * 2012-08-29 2014-08-13 江门市新会区光华生物科技有限公司 Polygonum multiflorum nutrient tablet and making method thereof
TWI826474B (en) 2018-06-27 2023-12-21 日商第一三共股份有限公司 Granules containing diamine derivative, as well as use and manufacturing method thereof
CN109512789B (en) * 2018-11-22 2020-11-20 浙江华康药业股份有限公司 High-purity granular xylitol capable of being directly tabletted and preparation method thereof
CN112352958A (en) * 2020-11-09 2021-02-12 安阳市豫鑫木糖醇科技有限公司 Production process of xylitol granulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204115A (en) * 1990-12-12 1993-04-20 Suomen Xyrofin Oy Directly compressible xylitol and method
US5616361A (en) * 1988-01-11 1997-04-01 Cultor Ltd. Process for the production of a xylitol-based binding and diluting agent
WO1998011878A1 (en) * 1996-09-19 1998-03-26 Xyrofin Oy Directly compressible lactitol and method
WO2003051338A1 (en) * 2001-12-17 2003-06-26 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA869191B (en) * 1986-01-07 1987-07-29 Warner Lambert Co Polyvinylpyrrolidone-containing coating for comestibles
AU739767B2 (en) * 1997-10-15 2001-10-18 Merck Patent Gmbh Production of a directly compressible tabletting aid
US6270790B1 (en) * 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
IT1305308B1 (en) * 1999-03-26 2001-05-04 Biosint S P A HIGH-CONTENT GRANULATE OF L-CARNITINE OR ALCANOYL-L-CARNITINE, PARTICULARLY SUITABLE FOR THE PRODUCTION OF COMPRESSION TABS
US6264983B1 (en) * 1999-09-16 2001-07-24 Rhodia, Inc. Directly compressible, ultra fine acetaminophen compositions and process for producing same
CN1108107C (en) * 2000-01-11 2003-05-14 赵力 Xylitol lozenge and its production method
CN1582703A (en) * 2004-05-28 2005-02-23 许宏昌 Xylitol pellets composition and preparation thereof
CN1732905A (en) * 2004-08-09 2006-02-15 赵力 Directly tabletting xylitol powder and its production method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616361A (en) * 1988-01-11 1997-04-01 Cultor Ltd. Process for the production of a xylitol-based binding and diluting agent
US5204115A (en) * 1990-12-12 1993-04-20 Suomen Xyrofin Oy Directly compressible xylitol and method
WO1998011878A1 (en) * 1996-09-19 1998-03-26 Xyrofin Oy Directly compressible lactitol and method
WO2003051338A1 (en) * 2001-12-17 2003-06-26 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GARR J S M ET AL, INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 64, no. 2-3, 30 October 1990 (1990-10-30), pages 223 - 226, XP025557917, ISSN: 0378-5173, [retrieved on 19901030] *
MORRIS L E ET AL: "Characterization and performance of a new direct compression excipient for chewable tablets: Xylitab(R)", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, NEW YORK, NY, US, vol. 22, no. 9-10, 1 January 1996 (1996-01-01), pages 925 - 932, XP009131564, ISSN: 0363-9045 *
See also references of WO2006119697A1 *

Also Published As

Publication number Publication date
US20080161417A1 (en) 2008-07-03
CN1686089B (en) 2010-08-18
EP1852109A1 (en) 2007-11-07
CN1686089A (en) 2005-10-26
WO2006119697A1 (en) 2006-11-16

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