EP1539210A4 - Modified glp-1 receptor agonists and their pharmacological methods of use - Google Patents

Modified glp-1 receptor agonists and their pharmacological methods of use

Info

Publication number
EP1539210A4
EP1539210A4 EP03755799A EP03755799A EP1539210A4 EP 1539210 A4 EP1539210 A4 EP 1539210A4 EP 03755799 A EP03755799 A EP 03755799A EP 03755799 A EP03755799 A EP 03755799A EP 1539210 A4 EP1539210 A4 EP 1539210A4
Authority
EP
European Patent Office
Prior art keywords
receptor agonists
pharmacological methods
modified glp
glp
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03755799A
Other languages
German (de)
French (fr)
Other versions
EP1539210A2 (en
Inventor
Clark Pan
James P Whelan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharmaceuticals Corp
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of EP1539210A2 publication Critical patent/EP1539210A2/en
Publication of EP1539210A4 publication Critical patent/EP1539210A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP03755799A 2002-09-06 2003-09-04 Modified glp-1 receptor agonists and their pharmacological methods of use Withdrawn EP1539210A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40869602P 2002-09-06 2002-09-06
US408696P 2002-09-06
US43936903P 2003-01-09 2003-01-09
US439369P 2003-01-09
PCT/US2003/028093 WO2004022004A2 (en) 2002-09-06 2003-09-04 Modified glp-1 receptor agonists and their pharmacological methods of use

Publications (2)

Publication Number Publication Date
EP1539210A2 EP1539210A2 (en) 2005-06-15
EP1539210A4 true EP1539210A4 (en) 2006-06-07

Family

ID=31981605

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03755799A Withdrawn EP1539210A4 (en) 2002-09-06 2003-09-04 Modified glp-1 receptor agonists and their pharmacological methods of use

Country Status (5)

Country Link
EP (1) EP1539210A4 (en)
JP (1) JP2006501820A (en)
AU (1) AU2003273300A1 (en)
CA (1) CA2497794A1 (en)
WO (1) WO2004022004A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107308442A (en) * 2009-11-13 2017-11-03 赛诺菲-安万特德国有限公司 Include the pharmaceutical composition of the activators of GLP 1, insulin and methionine

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WO1991011457A1 (en) * 1990-01-24 1991-08-08 Buckley Douglas I Glp-1 analogs useful for diabetes treatment
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Patent Citations (10)

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US4423034A (en) * 1980-10-16 1983-12-27 Toyo Jozo Kabushiki Kaisha Process for the preparation of antibodies
US5958909A (en) * 1986-05-05 1999-09-28 The General Hospital Corporation Insulinotropic hormones and uses thereof
WO1991011457A1 (en) * 1990-01-24 1991-08-08 Buckley Douglas I Glp-1 analogs useful for diabetes treatment
US5545618A (en) * 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
US5861284A (en) * 1991-02-19 1999-01-19 Takeda Chemical Industries, Ltd. Method for producing a biologically active recombinant cysteine-free parathyroid hormone (1-34)
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WO2001004156A1 (en) * 1999-07-12 2001-01-18 Zealand Pharmaceuticals A/S Peptides that lower blood glucose levels
WO2001068112A2 (en) * 2000-03-14 2001-09-20 Goeke Burkhard Effects of glucagon-like peptide-1 (7-36) on antro-pyloro-duodenal motility
WO2003040309A2 (en) * 2001-10-05 2003-05-15 Bayer Pharmaceuticals Corporation Peptides acting as both glp-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107308442A (en) * 2009-11-13 2017-11-03 赛诺菲-安万特德国有限公司 Include the pharmaceutical composition of the activators of GLP 1, insulin and methionine

Also Published As

Publication number Publication date
EP1539210A2 (en) 2005-06-15
WO2004022004A3 (en) 2004-12-23
AU2003273300A8 (en) 2004-03-29
CA2497794A1 (en) 2004-03-18
JP2006501820A (en) 2006-01-19
AU2003273300A1 (en) 2004-03-29
WO2004022004A2 (en) 2004-03-18

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