EP1487414A4 - Antibiotic composition - Google Patents

Antibiotic composition

Info

Publication number: EP1487414A4
Authority: EP; European Patent Office
Prior art keywords: antibiotic composition; antibiotic; composition
Prior art date: 2002-03-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP03714005A

Other languages

German (de)

French (fr)

Other versions

EP1487414A2 (en

Inventor

Edward M Rudnic

James D Isbister

Jr Donald J Treacy

Sandra E Wassink

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

MiddleBrook Pharmaceuticals Inc

Original Assignee

Advancis Pharmaceutical Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-07

Filing date

2003-03-07

Publication date

2007-12-12

2002-03-07 Priority claimed from US10/093,214 external-priority patent/US6638532B2/en

2002-03-07 Priority claimed from US10/092,858 external-priority patent/US6632453B2/en

2002-03-07 Priority claimed from US10/093,321 external-priority patent/US6610328B2/en

2002-03-07 Priority claimed from US10/092,854 external-priority patent/US6627222B2/en

2002-03-07 Priority claimed from US10/092,811 external-priority patent/US6623758B2/en

2003-03-07 Application filed by Advancis Pharmaceutical Corp filed Critical Advancis Pharmaceutical Corp

2004-12-22 Publication of EP1487414A2 publication Critical patent/EP1487414A2/en

2007-12-12 Publication of EP1487414A4 publication Critical patent/EP1487414A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

EP03714005A 2002-03-07 2003-03-07 Antibiotic composition Withdrawn EP1487414A4 (en)

Applications Claiming Priority (11)

Application Number	Priority Date	Filing Date	Title
US93321		1993-07-16
US92854		1993-07-19
US10/093,214 US6638532B2 (en)	2000-02-24	2002-03-07	Tetracycline—doxycycline antibiotic composition
US10/092,858 US6632453B2 (en)	2000-02-24	2002-03-07	Ciprofoxacin-metronidazole antibiotic composition
US93214		2002-03-07
US92858		2002-03-07
US10/093,321 US6610328B2 (en)	2000-02-24	2002-03-07	Amoxicillin-clarithromycin antibiotic composition
US92811		2002-03-07
US10/092,854 US6627222B2 (en)	2000-02-24	2002-03-07	Amoxicillin-dicloxacillin antibiotic composition
US10/092,811 US6623758B2 (en)	2000-02-24	2002-03-07	Cephalosporin-metronidazole antibiotic composition
PCT/US2003/007118 WO2003075852A2 (en)	2002-03-07	2003-03-07	Antibiotic composition

Publications (2)

Publication Number	Publication Date
EP1487414A2 EP1487414A2 (en)	2004-12-22
EP1487414A4 true EP1487414A4 (en)	2007-12-12

Family

ID=27808882

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP03714005A Withdrawn EP1487414A4 (en)	2002-03-07	2003-03-07	Antibiotic composition

Country Status (4)

Country	Link
EP (1)	EP1487414A4 (en)
JP (1)	JP2005526059A (en)
CA (1)	CA2478121A1 (en)
WO (1)	WO2003075852A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6544555B2 (en)	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
US20020068078A1 (en)	2000-10-13	2002-06-06	Rudnic Edward M.	Antifungal product, use and formulation thereof
AUPS167602A0 (en) *	2002-04-12	2002-05-16	F.H. Faulding & Co. Limited	An improved modified release preparation
CA2572292A1 (en) *	2004-07-02	2006-02-09	Advancis Pharmaceutical Corporation	Tablet for pulsed delivery
WO2006110807A1 (en) *	2005-04-12	2006-10-19	Elan Pharma International Limited	Controlled release compositions comprising a cephalosporin for the treatment of a bacterial infection
CN101257892B (en)	2005-05-18	2013-01-02	达沃尔泰拉公司	Colonic delivery of adsorbents
US8048413B2 (en)	2006-05-17	2011-11-01	Helene Huguet	Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
PT2294012E (en) *	2008-05-07	2014-10-15	Salix Pharmaceuticals Ltd	Administration of a bowel cleanser and an antibiotic for the treatment of bowel disease
US9119793B1 (en)	2011-06-28	2015-09-01	Medicis Pharmaceutical Corporation	Gastroretentive dosage forms for doxycycline
US10842802B2 (en)	2013-03-15	2020-11-24	Medicis Pharmaceutical Corporation	Controlled release pharmaceutical dosage forms

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001062195A1 (en) *	2000-02-24	2001-08-30	Advancis Pharmaceutical Corporation	Antibiotic and antifungal compositions
US20010046984A1 (en) *	2000-02-24	2001-11-29	Rudnic Edward M.	Antibiotic composition with inhibitor
US20010048944A1 (en) *	2000-02-24	2001-12-06	Rudnic Edward M.	Antibiotic product, use and formulation thereof
US20020013345A1 (en) *	1998-10-09	2002-01-31	Charles L. Berman	Treatment of diseases of the eye characterized by the formation of metalloproteinase

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS601128A (en) *	1983-06-15	1985-01-07	Shionogi & Co Ltd	Long-acting cefaclor preparation
JPS61210025A (en) *	1985-03-14	1986-09-18	Teisan Seiyaku Kk	Stabilized antibioitc complex granule preparation
US4728512A (en) *	1985-05-06	1988-03-01	American Home Products Corporation	Formulations providing three distinct releases
US4794001A (en) *	1986-03-04	1988-12-27	American Home Products Corporation	Formulations providing three distinct releases
JPS63162619A (en) *	1986-12-25	1988-07-06	Teisan Seiyaku Kk	Delayed soluble granule and sustained release complex granule using said granule
NL8800223A (en) *	1987-04-21	1988-11-16	Philips Nv	SYSTEM FOR RECORDING AN INFORMATION SIGNAL, A REGISTRATION CARRIER AND A REGISTRATION DEVICE FOR USE IN THE SYSTEM.
US5326570A (en) *	1991-07-23	1994-07-05	Pharmavene, Inc.	Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US5260068A (en) *	1992-05-04	1993-11-09	Anda Sr Pharmaceuticals Inc.	Multiparticulate pulsatile drug delivery system
US5260069A (en) *	1992-11-27	1993-11-09	Anda Sr Pharmaceuticals Inc.	Pulsatile particles drug delivery system
EP0804174A4 (en) *	1993-07-21	1998-09-09	Univ Kentucky Res Found	A multicompartment hard capsule with control release properties
DE19718012C1 (en) *	1997-04-29	1998-10-08	Jenapharm Gmbh	Process for the production of orally applicable solid pharmaceutical forms with controlled release of active substances
US5840329A (en) *	1997-05-15	1998-11-24	Bioadvances Llc	Pulsatile drug delivery system
AUPP437698A0 (en) *	1998-06-30	1998-07-23	Baumgart, Karl	Methods for treatment of coronary, carotid and other vascular disease

2003
- 2003-03-07 CA CA002478121A patent/CA2478121A1/en not_active Abandoned
- 2003-03-07 JP JP2003574128A patent/JP2005526059A/en active Pending
- 2003-03-07 WO PCT/US2003/007118 patent/WO2003075852A2/en active Application Filing
- 2003-03-07 EP EP03714005A patent/EP1487414A4/en not_active Withdrawn

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20020013345A1 (en) *	1998-10-09	2002-01-31	Charles L. Berman	Treatment of diseases of the eye characterized by the formation of metalloproteinase
WO2001062195A1 (en) *	2000-02-24	2001-08-30	Advancis Pharmaceutical Corporation	Antibiotic and antifungal compositions
US20010046984A1 (en) *	2000-02-24	2001-11-29	Rudnic Edward M.	Antibiotic composition with inhibitor
US20010048944A1 (en) *	2000-02-24	2001-12-06	Rudnic Edward M.	Antibiotic product, use and formulation thereof

Also Published As

Publication number	Publication date
EP1487414A2 (en)	2004-12-22
WO2003075852A3 (en)	2004-07-15
AU2003218024B2 (en)	2008-09-11
WO2003075852A2 (en)	2003-09-18
CA2478121A1 (en)	2003-09-18
AU2003218024A1 (en)	2003-09-22
JP2005526059A (en)	2005-09-02

Legal Events

Date	Code	Title	Description
2004-11-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-12-22	17P	Request for examination filed	Effective date: 20040930
2004-12-22	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
2004-12-22	AX	Request for extension of the european patent	Extension state: AL LT LV MK
2005-03-09	RIN1	Information on inventor provided before grant (corrected)	Inventor name: WASSINK, SANDRA, E. Inventor name: TREACY, JR., DONALD, J. Inventor name: ISBISTER, JAMES, D. Inventor name: RUDNIC, EDWARD, M.
2006-04-12	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: ADVANCIS PHARMACEUTICAL CORPORATION
2007-12-12	A4	Supplementary search report drawn up and despatched	Effective date: 20071114
2008-10-08	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: MIDDLEBROOK PHARMACEUTICALS, INC.
2008-10-29	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: MIDDLEBROOK PHARMACEUTICALS, INC.
2010-02-19	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2010-03-24	18D	Application deemed to be withdrawn	Effective date: 20091001

Publication	Publication Date	Title
GB0220467D0 (en)	2002-10-09	Composition
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