EP1410845A2 - Pipette comprising a coloured braid of synthetic fibres for coding at least a characteristic of the pipette - Google Patents

Pipette comprising a coloured braid of synthetic fibres for coding at least a characteristic of the pipette Download PDF

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Publication number
EP1410845A2
EP1410845A2 EP03356150A EP03356150A EP1410845A2 EP 1410845 A2 EP1410845 A2 EP 1410845A2 EP 03356150 A EP03356150 A EP 03356150A EP 03356150 A EP03356150 A EP 03356150A EP 1410845 A2 EP1410845 A2 EP 1410845A2
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EP
European Patent Office
Prior art keywords
pipette
braid
piece
characteristic
fibrous material
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP03356150A
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German (de)
French (fr)
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EP1410845A3 (en
EP1410845B1 (en
Inventor
Viviane Judic
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ALP Articles de Laboratoire de Precision SAS
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ALP Articles de Laboratoire de Precision SAS
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Publication of EP1410845A3 publication Critical patent/EP1410845A3/en
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Publication of EP1410845B1 publication Critical patent/EP1410845B1/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes

Definitions

  • the invention relates to the technical field of laboratory instruments, in particular laboratory pipettes, in particular disposable pipettes for unique, used in biological laboratories, medical analyzes, serology, immunology, microbiology or industrial laboratories ...
  • the European patent EP 261 023 proposes a laboratory pipette of the type comprising means of characterization allowing a user to identify immediately and without error the maximum or nominal volume of the pipette, characterized in that the means of characterization consist of at least one piece of colored matter whose color is the maximum or nominal volume of the pipette and is inserted in the suction end of the pipette.
  • the piece of colored material constitutes reliable characterization means, very low cost, visible from outside by the user in any circumstance, while remaining safe from external aggression.
  • a color code in accordance with the standard in a one-to-one relationship with the maximum or nominal volumes of Common pipettes is used. This standard specifies, for example, that pipettes 1 ml are characterized by yellow, those of 2 ml by green, those of 5 ml by the blue, those of 10 ml by the orange, those of 25 ml by the red ....
  • the piece of colored material used is preferably made of fibrous material or hydrophobic cell, especially wood viscose, cellulose, cotton or other.
  • the dimensions of the piece of colored material are adapted according to the diameter of the suction end of the pipette, so that it can be inserted and himself by simple contact with the walls. In use, it has been found that wood or cotton colored viscose buffer used tends to fray and that elementary fibers may then fall into the aspirated liquid. It would therefore be desirable to remove these risks of contamination.
  • the fibrous buffers used are in the form of small cylinders of material whose diameter has certain irregularities. Variations of the diameter of the fibrous piece influence the rate of flow of the pipetted liquid obtained.
  • the subject of the present invention is an improvement of laboratory pipettes already known, these pipettes have to present the properties mentioned above and in addition to guaranteeing any risk of contamination of the liquid at pipette.
  • Another object of the invention is to provide pipettes provided with a piece of fibrous material, also called stamp, ensuring their identification fast, this buffer having to present a good cohesion after implementation in the pipette and a reduced tendency to fraying.
  • the buffer used in this invention is further characterized by the great regularity of its diameter and its porosity, which makes it possible to obtain a regular flow of liquid.
  • the invention relates to a laboratory pipette consisting in particular of a transparent tube having a liquid withdrawal end and a suction end into which is inserted a piece of fibrous material of a color corresponding to at least one characteristic of the pipette and in particular its nominal volume.
  • the piece of fibrous material is in the form of a braid of intertwined synthetic fiber yarns, said braid being folded so that that the fold thus formed is positioned towards the inside of the pipette.
  • the subject of the invention is also a method for identifying at least one characteristic, and in particular the nominal volume of a laboratory pipette consisting in particular of a transparent tube comprising an end of sampling of a liquid and a suction end comprising the insertion of a piece of fibrous material whose color corresponds to the characteristic identifiable pipette.
  • a laboratory pipette consisting in particular of a transparent tube comprising an end of sampling of a liquid and a suction end comprising the insertion of a piece of fibrous material whose color corresponds to the characteristic identifiable pipette.
  • it is used as piece of fibrous material, a braid of intertwined synthetic fiber yarns, that it is folded before insertion and that is inserted into the suction end, so that that the fold thus formed is positioned towards the inside of the pipette.
  • Fig. 1 represents an example of a pipette according to the invention.
  • Fig. 2 represents, on a larger scale, an example of braided fibrous pads that can be used in the pipettes of the invention.
  • Figs. 3 and 4 show other suitable braiding variants.
  • Fig. 5 is a table giving different characteristics of braided pads used in pipettes according to the invention.
  • FIG. 1 illustrates by way of non-limiting example a pipette 1 according to the invention for taking a precise volume of a chemical or biological liquid.
  • a tube 3 is extended at one of its ends into a tube of the same or smaller diameter through which the liquid is either removed or discharged from the pipette, this end is called the sampling end 4 .
  • the tube 3 is extended into another tube whose diameter, depending on the volume of the pipette, is identical to the diameter of the tube 3 or lower as shown in FIG. 1 .
  • This end, through which gases are drawn or expelled is appointed suction end 5.
  • the tube 3 has in its main part graduations 6 located outside the tube.
  • a piece of fibrous material 2 is trapped inside the suction end 5 of the pipette, preferably in a remote part of any graduation or registration.
  • the fibrous piece 2 is made of synthetic fibers, preferred to the natural fibers of the cotton or wood viscose type which can cause cutting problems and also to influence the pipetting operation, when, unfortunately, the liquid to be pipetted comes into contact of the fibrous piece.
  • the fibers of animal or natural origin have the risk of contaminating the liquids to be taken and thus to falsify the analyzes.
  • the use of synthetic fibers makes it possible to limit the deteriorations of the chemical and / or biological liquids taken, if the latter came into contact with or near the fibrous piece 2 by a manipulation error.
  • a buffer of hydrophobic synthetic fibers will be used. Hydrophobic means a material that does not retain water.
  • this buffer loses its characteristics especially for the regulation of the flow and, on the other hand, that liquid is retained in the buffer and thereby changes the pipetted volume.
  • the fibrous piece used is made of a sterile material that is inert with respect to different biological or chemical liquids to be taken, in case these liquids would come into contact with said fibrous piece during the pipetting operation.
  • the fibrous piece 2 according to the invention is inserted in a folded form.
  • the fibrous piece in braid form is folded on itself so as to form a fold extending transversely to the longitudinal axis of the braid.
  • the braid is folded into two equal parts and then inserted by first entering the tube forming the end 5, the fold 2 1 .
  • the ply 2 1 formed is located not on the side of the open end of the suction end 5 but to the side of the main part of the tube 3.
  • this folding provides a spring effect reinforcing maintaining the fibrous piece 2 inside the suction end 5.
  • the fibrous piece is present in the form of a braid.
  • Braid means an interlacing of at least three fiber yarns synthetic.
  • the thread consists of many filaments grouped together, the filaments that can be defined as very small diameter threads. Each thread contains, for example, 128 filaments.
  • the braid will consist for example of 4, 8 or 16 intertwined threads. The used threads to be textured. The characteristics of the braid must be chosen so as to leave pass the gases to allow the aspiration and the evacuation of the liquid taken. By therefore, the braided fibrous piece must not constitute a hermetic stopper for the laboratory pipette. Braiding is chosen according to the speed flow of the desired liquid, this braiding determines the porosity of the fibrous piece and therefore its ability to let in air, which conditions the flow rate of the liquid obtained as a function of the fill rate of the pipette.
  • braiding named half-occupation, tandem occupation, or preferably, normal occupation as shown respectively in FIGS. 3, 4 and 2 .
  • These types of braiding are well known to those skilled in the art and are obtained according to conventional braiding techniques.
  • Braiders 8 or 16 spindles may, for example, be implemented.
  • colored buffer size 2 are adapted according to the diameter of the tube 3 at its suction end 5, so that the latter can be inserted and stuck to itself in the end, by simple contact with the internal walls.
  • the number of threads present in the braid will be a function of the diameter of the fibrous pad.
  • the braid will comprise for example 16 threads and for smaller diameters, for example 4 threads.
  • the number of wires and the characteristics of the braid are chosen according to the nominal volume of the pipette, in order to obtain a similar flow rate irrespective of the volume of the pipette.
  • the skilled person will be able to choose the characteristics of the braid according to the nominal volume of the pipette, the diameter of the suction end 5 and in particular flow velocity. These characteristics are, in particular, the diutage - number of meshes or round-trip existing on a centimeter of braid - the titration of the threads, the weight per linear meter of the braid.
  • the table presented Fig. 5 gives, without limitation, the characteristics of the braids that can be used according to the nominal volume of the pipette.
  • the braid is colored, each chosen color corresponding to a value of one characteristic of the pipette and in particular its nominal volume.
  • the current The subject of the invention is therefore a method for identifying at least one characteristic, and in particular the nominal volume of a pipette.
  • the choice of diameter and the braiding density of the piece of fibrous material used makes it possible to obtain the desired flow rate for the liquid contained in the pipette during its use.
  • Such braids are tinted in mass and therefore present a great homogeneity in the dyeing.
  • Polypropylene fibers are particularly suitable for mass dyeing, that is to say carried out before the development of son.
  • the dye used is of the type resistant to light, liquids and different types sterilization. We can use different dyes that hang perfectly synthetic fibers and in particular polypropylene.
  • the fibrous piece 2 is inserted in a simple way inside a laboratory pipette, such as that shown in FIG. 1 , after being previously folded.
  • the assembly is then packaged and sterilized, for example with ethylene oxide followed by rinsing with air or with nuclear radiation.

Abstract

The piece (2) of fibrous material is of a color corresponding to a characteristic of the pipette, in particular its nominal volume. The piece of fibrous material is in the form of a tress of interlaced synthetic fibre threads, folded so the fold formed is positioned towards the inside of the pipette An INDEPENDENT claim is also included for a method of identifying at least one characteristic, in particular the nominal volume of a laboratory pipette by inserting a piece of fibrous material into the sucking end whose color corresponds to the identifiable characteristic of the pipette. The material is a tress of interlaced synthetic fibres which is folded before insertion so the fold is placed towards the inside of the pipette. The speed of flow of the liquid is regulated by the choice of the number of threads in the tress and its weight per linear meter.

Description

L'invention concerne le domaine technique des instruments de laboratoire, en particulier des pipettes de laboratoire, notamment des pipettes jetables à usage unique, utilisées dans les laboratoires de biologie, analyses médicales, sérologie, immunologie, microbiologie ou encore les laboratoires industriels...The invention relates to the technical field of laboratory instruments, in particular laboratory pipettes, in particular disposable pipettes for unique, used in biological laboratories, medical analyzes, serology, immunology, microbiology or industrial laboratories ...

Il est connu que des pipettes de différents volumes sont relativement peu différentes les unes des autres. Aussi, lorsque de nombreuses pipettes de volume différent sont mélangées, il est très difficile de les distinguer, surtout lorsque des manipulations rapides ou nombreuses doivent être effectuées.It is known that pipettes of different volumes are relatively different from each other. Also, when many volume pipettes different are mixed, it is very difficult to distinguish them, especially when fast or many manipulations must be performed.

Différentes propositions de l'art antérieur visent à fournir des pipettes de laboratoire pouvant être identifiées rapidement et sans ambiguïté quant à leur caractéristique principale et en particulier leur volume nominal. Il est alors possible de choisir instantanément une pipette possédant une caractéristique donnée, au milieu d'un groupe de pipettes de caractéristiques diverses. Le brevet européen EP 261 023 propose une pipette de laboratoire du type comportant des moyens de caractérisation permettant à un utilisateur d'identifier immédiatement et sans erreur possible le volume maximum ou nominal de la pipette, caractérisée en ce que les moyens de caractérisation sont constitués d'au moins un morceau de matière colorée dont la couleur correspond au volume maximum ou nominal de la pipette et qui est inséré dans l'extrémité d'aspiration de la pipette. Le morceau de matière colorée constitue un moyen de caractérisation fiable, de très faible prix de revient, visible de l'extérieur par l'utilisateur en toute circonstance, tout en restant à l'abri des agressions extérieures. En général, un code de couleur en accord avec la norme internationale en relation bi-univoque avec les volumes maximas ou nominaux des pipettes courantes est utilisé. Cette norme précise, par exemple, que les pipettes de 1 ml sont caractérisées par le jaune, celles de 2 ml par le vert, celles de 5 ml par le bleu, celles de 10 ml par l'orange, celles de 25 ml par le rouge....Various proposals of the prior art aim at providing pipettes of laboratory that can be quickly and unambiguously identified as to their main characteristic and in particular their nominal volume. It is then possible to instantly choose a pipette with a given characteristic, in the middle a group of pipettes of various characteristics. The European patent EP 261 023 proposes a laboratory pipette of the type comprising means of characterization allowing a user to identify immediately and without error the maximum or nominal volume of the pipette, characterized in that the means of characterization consist of at least one piece of colored matter whose color is the maximum or nominal volume of the pipette and is inserted in the suction end of the pipette. The piece of colored material constitutes reliable characterization means, very low cost, visible from outside by the user in any circumstance, while remaining safe from external aggression. In general, a color code in accordance with the standard in a one-to-one relationship with the maximum or nominal volumes of Common pipettes is used. This standard specifies, for example, that pipettes 1 ml are characterized by yellow, those of 2 ml by green, those of 5 ml by the blue, those of 10 ml by the orange, those of 25 ml by the red ....

Le morceau de matière colorée utilisé est de préférence en matière fibreuse ou cellulaire hydrophobe, notamment en viscose de bois, cellulose, coton ou autre. Les dimensions du morceau de matière colorée sont adaptées en fonction du diamètre de l'extrémité d'aspiration de la pipette, de façon à pouvoir être inséré et être coincé de lui-même par simple contact avec les parois. A l'usage, il a été constaté que le tampon de viscose de bois ou de coton coloré utilisé a tendance à s'effilocher et que des fibres élémentaires peuvent alors tomber dans le liquide aspiré. Il serait donc souhaitable de supprimer ces risques de contamination.The piece of colored material used is preferably made of fibrous material or hydrophobic cell, especially wood viscose, cellulose, cotton or other. The dimensions of the piece of colored material are adapted according to the diameter of the suction end of the pipette, so that it can be inserted and himself by simple contact with the walls. In use, it has been found that wood or cotton colored viscose buffer used tends to fray and that elementary fibers may then fall into the aspirated liquid. It would therefore be desirable to remove these risks of contamination.

De plus, les tampons fibreux utilisés se présentent sous la forme de petits cylindres de matière dont le diamètre présente certaines irrégularités. Des variations importantes du diamètre du morceau fibreux influencent la vitesse d'écoulement du liquide pipeté obtenu.In addition, the fibrous buffers used are in the form of small cylinders of material whose diameter has certain irregularities. Variations of the diameter of the fibrous piece influence the rate of flow of the pipetted liquid obtained.

Dans ce contexte, la présente invention a pour objet un perfectionnement des pipettes de laboratoire déjà connues, ces pipettes se devant de présenter les propriétés ci-dessus mentionnées et en plus de garantir tout risque de contamination du liquide à pipeter.In this context, the subject of the present invention is an improvement of laboratory pipettes already known, these pipettes have to present the properties mentioned above and in addition to guaranteeing any risk of contamination of the liquid at pipette.

Un autre objectif de l'invention est de fournir des pipettes munies d'un morceau de matière fibreuse, également nommé tampon, assurant leur identification rapide, ce tampon devant présenter une bonne cohésion après mise en place dans la pipette et une tendance réduite à l'effilochage. Le tampon utilisé, dans la présente invention est de plus caractérisé par la grande régularité que présentent son diamètre et sa porosité, ce qui permet d'obtenir un écoulement de liquide régulier.Another object of the invention is to provide pipettes provided with a piece of fibrous material, also called stamp, ensuring their identification fast, this buffer having to present a good cohesion after implementation in the pipette and a reduced tendency to fraying. The buffer used in this invention is further characterized by the great regularity of its diameter and its porosity, which makes it possible to obtain a regular flow of liquid.

L'invention concerne une pipette de laboratoire constituée notamment d'un tube transparent comportant une extrémité de prélèvement d'un liquide et une extrémité d'aspiration dans laquelle est inséré un morceau de matière fibreuse d'une couleur correspondant au moins à une caractéristique de la pipette et en particulier à son volume nominal. Le morceau de matière fibreuse se présente sous la forme d'une tresse de fils de fibres synthétiques entrelacés, ladite tresse étant pliée de façon à ce que le pli ainsi formé soit positionné vers l'intérieur de la pipette.The invention relates to a laboratory pipette consisting in particular of a transparent tube having a liquid withdrawal end and a suction end into which is inserted a piece of fibrous material of a color corresponding to at least one characteristic of the pipette and in particular its nominal volume. The piece of fibrous material is in the form of a braid of intertwined synthetic fiber yarns, said braid being folded so that that the fold thus formed is positioned towards the inside of the pipette.

L'invention a également pour objet un procédé pour identifier au moins une caractéristique, et en particulier le volume nominal d'une pipette de laboratoire constituée notamment d'un tube transparent comportant une extrémité de prélèvement d'un liquide et une extrémité d'aspiration comprenant l'insertion d'un morceau de matière fibreuse dont la couleur correspond à la caractéristique identifiable de la pipette. Dans le procédé selon l'invention, on utilise en tant que morceau de matière fibreuse, une tresse de fils de fibres synthétiques entrelacés, que l'on plie avant insertion et que l'on insère dans l'extrémité d'aspiration, de façon à ce que le pli ainsi formé soit positionné vers l'intérieur de la pipette. The subject of the invention is also a method for identifying at least one characteristic, and in particular the nominal volume of a laboratory pipette consisting in particular of a transparent tube comprising an end of sampling of a liquid and a suction end comprising the insertion of a piece of fibrous material whose color corresponds to the characteristic identifiable pipette. In the process according to the invention, it is used as piece of fibrous material, a braid of intertwined synthetic fiber yarns, that it is folded before insertion and that is inserted into the suction end, so that that the fold thus formed is positioned towards the inside of the pipette.

Diverses autres caractéristiques ressortent de la description faite ci-dessous en référence aux dessins annexés qui montrent, à titre d'exemples non limitatifs, des formes de réalisation de l'objet de l'invention.Various other features are apparent from the description given below in reference to the accompanying drawings which show, by way of non-limiting examples, embodiments of the subject of the invention.

La Fig. 1 représente un exemple de pipette conforme à l'invention. Fig. 1 represents an example of a pipette according to the invention.

La Fig. 2 représente, à plus grande échelle, un exemple de tampons fibreux tressés pouvant être utilisés dans les pipettes de l'invention. Fig. 2 represents, on a larger scale, an example of braided fibrous pads that can be used in the pipettes of the invention.

Les Fig. 3 et 4 représentent d'autres variantes de tressage adaptées. Figs. 3 and 4 show other suitable braiding variants.

La Fig. 5 est un tableau donnant différentes caractéristiques de tampons tressés utilisés dans des pipettes selon l'invention. Fig. 5 is a table giving different characteristics of braided pads used in pipettes according to the invention.

Hormis le morceau de matière fibreuse utilisée, les pipettes de laboratoire selon l'invention sont de structure et de fonctionnement classique, bien connus dans l'art antérieur. La Fig. 1 illustre à titre d'exemple non limitatif une pipette 1 selon l'invention permettant de prélever un volume précis d'un liquide chimique ou biologique. Un tel tube 3 se prolonge à une de ses extrémités en un tube de diamètre identique ou plus faible par lequel le liquide est soit prélevé, soit évacué de la pipette, cette extrémité est nommée extrémité 4 de prélèvement. A son autre extrémité, le tube 3 se prolonge en un autre tube dont le diamètre, en fonction du volume de la pipette, est identique au diamètre du tube 3 ou plus faible comme illustré à la Fig. 1. Cette extrémité, par laquelle des gaz sont aspirés ou expulsés, est nommée extrémité 5 d'aspiration. Le tube 3 comporte dans sa partie principale des graduations 6 situées à l'extérieur du tube. Comme dans les pipettes de laboratoire décrites dans l'art antérieur EP 261 023, un morceau de matière fibreuse 2 est coincé à l'intérieur de l'extrémité 5 d'aspiration de la pipette, de préférence, dans une partie éloignée de toute graduation ou inscription.Apart from the piece of fibrous material used, the laboratory pipettes according to the invention are of conventional structure and operation, well known in the prior art. Fig. 1 illustrates by way of non-limiting example a pipette 1 according to the invention for taking a precise volume of a chemical or biological liquid. Such a tube 3 is extended at one of its ends into a tube of the same or smaller diameter through which the liquid is either removed or discharged from the pipette, this end is called the sampling end 4 . At its other end, the tube 3 is extended into another tube whose diameter, depending on the volume of the pipette, is identical to the diameter of the tube 3 or lower as shown in FIG. 1 . This end, through which gases are drawn or expelled is appointed suction end 5. The tube 3 has in its main part graduations 6 located outside the tube. As in laboratory pipettes described in the prior art EP 261 023, a piece of fibrous material 2 is trapped inside the suction end 5 of the pipette, preferably in a remote part of any graduation or registration.

Selon l'invention, le morceau fibreux 2 est constitué de fibres synthétiques, préférées aux fibres naturelles de type coton ou viscose de bois qui peuvent poser des problèmes de découpe et également influencer l'opération de pipetage, lorsque malencontreusement le liquide à pipeter vient au contact du morceau fibreux. Dans ce cas, les fibres d'origine animale ou naturelle présentent le risque de contaminer les liquides à prélever et donc de fausser les analyses. L'utilisation de fibres synthétiques permet de limiter les détériorations des liquides chimiques et/ou biologiques prélevés, si ces derniers venaient au contact ou au voisinage du morceau fibreux 2 par une erreur de manipulation. De façon avantageuse, un tampon en fibres synthétiques hydrophobes sera utilisé. Par hydrophobe, on entend une matière qui ne retienne pas l'eau. Ainsi, on évite en cas de pipetage trop important où le liquide vient au contact du tampon, d'une part, que ce tampon perde ses caractéristiques notamment pour la régulation de l'écoulement et, d'autre part, que du liquide soit retenu dans le tampon et de ce fait modifie le volume pipeté.According to the invention, the fibrous piece 2 is made of synthetic fibers, preferred to the natural fibers of the cotton or wood viscose type which can cause cutting problems and also to influence the pipetting operation, when, unfortunately, the liquid to be pipetted comes into contact of the fibrous piece. In this case, the fibers of animal or natural origin have the risk of contaminating the liquids to be taken and thus to falsify the analyzes. The use of synthetic fibers makes it possible to limit the deteriorations of the chemical and / or biological liquids taken, if the latter came into contact with or near the fibrous piece 2 by a manipulation error. Advantageously, a buffer of hydrophobic synthetic fibers will be used. Hydrophobic means a material that does not retain water. Thus, it is avoided in case of excessive pipetting where the liquid comes into contact with the buffer, on the one hand, that this buffer loses its characteristics especially for the regulation of the flow and, on the other hand, that liquid is retained in the buffer and thereby changes the pipetted volume.

On utilisera de préférence des fibres de polypropylène, matériau résistant aux produits chimiques et notamment aux attaques acido-basiques. En effet, de façon avantageuse, le morceau fibreux utilisé est en un matériau stérile et inerte vis-à-vis des différents liquides biologiques ou chimiques devant être prélevés, au cas où ces liquides viendraient au contact dudit morceau fibreux lors de l'opération de pipetage.Polypropylene fibers, a material resistant to chemicals and in particular to acid-base attacks. Indeed, so advantageously, the fibrous piece used is made of a sterile material that is inert with respect to different biological or chemical liquids to be taken, in case these liquids would come into contact with said fibrous piece during the pipetting operation.

Pour éviter que des fibres ne tombent dans le liquide à pipeter, le morceau fibreux 2 selon l'invention est inséré sous une forme pliée. Le morceau fibreux sous forme de tresse est plié sur lui-même de façon à former un pli s'étendant transversalement à l'axe longitudinal de la tresse. De façon avantageuse, la tresse est pliée en deux parties égales puis insérée en faisant tout d'abord pénétrer dans le tube formant l'extrémité 5, le pli 21. Ainsi, le pli 21 formé est situé non pas du côté de l'extrémité ouverte de l'extrémité 5 d'aspiration mais au contraire du côté de la partie principale du tube 3. D'une part, un tel pliage permet d'obtenir une coupe franche en direction du liquide, cette coupe franche correspondant au pli 21 représenté Fig. 2. D'autre part, ce pliage permet d'obtenir un effet ressort renforçant le maintien du morceau fibreux 2 à l'intérieur de l'extrémité 5 d'aspiration.To prevent fibers from falling into the liquid to be pipetted, the fibrous piece 2 according to the invention is inserted in a folded form. The fibrous piece in braid form is folded on itself so as to form a fold extending transversely to the longitudinal axis of the braid. Advantageously, the braid is folded into two equal parts and then inserted by first entering the tube forming the end 5, the fold 2 1 . Thus, the ply 2 1 formed is located not on the side of the open end of the suction end 5 but to the side of the main part of the tube 3. On the one hand, allows such folding of obtain a clean cut towards the liquid, this clean cut corresponding to the fold 2 1 shown in FIG. 2. On the other hand, this folding provides a spring effect reinforcing maintaining the fibrous piece 2 inside the suction end 5.

Selon une autre caractéristique essentielle de l'invention, le morceau fibreux se présente sous la forme d'une tresse.According to another essential characteristic of the invention, the fibrous piece is present in the form of a braid.

Par tresse, on entend un entrelacement d'au moins trois fils de fibres synthétiques. Le fil est constitué de nombreux filaments regroupés entre eux, les filaments pouvant être définis comme des fils de très petit diamètre. Chaque fil contient, par exemple, 128 filaments. En fonction du volume de la pipette, la tresse sera constituée par exemple de 4, 8 ou 16 fils entrelacés. Les fils utilisés pourront être texturés. Les caractéristiques de la tresse doivent être choisies de façon à laisser passer les gaz afin de permettre l'aspiration puis l'évacuation du liquide prélevé. Par conséquent, le morceau fibreux tressé ne doit pas constituer un bouchon hermétique pour la pipette de laboratoire. Le tressage est choisi en fonction de la vitesse d'écoulement du liquide désiré, ce tressage détermine la porosité du morceau fibreux et donc sa capacité à laisser passer l'air, ce qui conditionne la vitesse d'écoulement du liquide obtenue en fonction du taux de remplissage de la pipette.Braid means an interlacing of at least three fiber yarns synthetic. The thread consists of many filaments grouped together, the filaments that can be defined as very small diameter threads. Each thread contains, for example, 128 filaments. Depending on the volume of the pipette, the braid will consist for example of 4, 8 or 16 intertwined threads. The used threads to be textured. The characteristics of the braid must be chosen so as to leave pass the gases to allow the aspiration and the evacuation of the liquid taken. By therefore, the braided fibrous piece must not constitute a hermetic stopper for the laboratory pipette. Braiding is chosen according to the speed flow of the desired liquid, this braiding determines the porosity of the fibrous piece and therefore its ability to let in air, which conditions the flow rate of the liquid obtained as a function of the fill rate of the pipette.

On pourra utiliser un tressage nommé demi-occupation, occupation en tandem, ou de préférence, occupation normale comme représenté respectivement aux Fig. 3, 4 et 2. Ces types de tressage sont bien connus de l'homme du métier et sont obtenus selon les techniques classiques de tressage. Des tresseuses à 8 ou 16 fuseaux pourront, par exemple, être mises en oeuvre. Par ailleurs, les dimensions du tampon coloré 2 sont adaptées en fonction du diamètre du tube 3 à son extrémité 5 d'aspiration, de façon à que ce dernier puisse être inséré et coincé de lui-même dans cette extrémité, par simple contact avec les parois internes.It will be possible to use a braiding named half-occupation, tandem occupation, or preferably, normal occupation as shown respectively in FIGS. 3, 4 and 2 . These types of braiding are well known to those skilled in the art and are obtained according to conventional braiding techniques. Braiders 8 or 16 spindles may, for example, be implemented. Furthermore, colored buffer size 2 are adapted according to the diameter of the tube 3 at its suction end 5, so that the latter can be inserted and stuck to itself in the end, by simple contact with the internal walls.

Le nombre de fils présents dans la tresse sera fonction du diamètre du tampon fibreux. Pour les diamètres les plus importants, la tresse comportera par exemple 16 fils et pour les plus petits diamètres, par exemple 4 fils. Le nombre de fils et les caractéristiques de la tresse sont choisis en fonction du volume nominal de la pipette, afin d'obtenir une vitesse d'écoulement semblable quel que soit le volume de la pipette. L'homme du métier sera à même de choisir les caractéristiques de la tresse en fonction du volume nominal de la pipette, du diamètre de l'extrémité 5 d'aspiration et de la vitesse d'écoulement notamment. Ces caractéristiques sont, en particulier, le diutage ― nombre de mailles ou d'aller-retour existant sur un centimètre de tresse ― le titrage des fils, le poids au mètre linéaire de la tresse. Avantageusement, on utilisera une tresse présentant un poids au mètre linéaire compris entre 0,5 et 4,5 g/m. Le tableau présenté Fig. 5 donne, sans caractère limitatif, les caractéristiques des tresses pouvant être utilisées en fonction du volume nominal de la pipette.The number of threads present in the braid will be a function of the diameter of the fibrous pad. For the largest diameters, the braid will comprise for example 16 threads and for smaller diameters, for example 4 threads. The number of wires and the characteristics of the braid are chosen according to the nominal volume of the pipette, in order to obtain a similar flow rate irrespective of the volume of the pipette. The skilled person will be able to choose the characteristics of the braid according to the nominal volume of the pipette, the diameter of the suction end 5 and in particular flow velocity. These characteristics are, in particular, the diutage - number of meshes or round-trip existing on a centimeter of braid - the titration of the threads, the weight per linear meter of the braid. Advantageously, use a braid having a weight per linear meter of between 0.5 and 4.5 g / m. The table presented Fig. 5 gives, without limitation, the characteristics of the braids that can be used according to the nominal volume of the pipette.

La tresse est colorée, chaque couleur choisie correspondant à une valeur d'une caractéristique de la pipette et en particulier à son volume nominal. La présente invention a donc pour objet un procédé pour identifier au moins une caractéristique, et en particulier le volume nominal d'une pipette. De plus, le choix du diamètre et de la densité de tressage du morceau de matière fibreuse utilisé permet d'obtenir la vitesse d'écoulement désirée pour le liquide contenu dans la pipette lors de son utilisation.The braid is colored, each chosen color corresponding to a value of one characteristic of the pipette and in particular its nominal volume. The current The subject of the invention is therefore a method for identifying at least one characteristic, and in particular the nominal volume of a pipette. In addition, the choice of diameter and the braiding density of the piece of fibrous material used makes it possible to obtain the desired flow rate for the liquid contained in the pipette during its use.

De telles tresses sont teintées en masse et présentent donc une grande homogénéité dans la teinture. Les fibres de polypropylène sont particulièrement adaptées à une teinture en masse, c'est-à-dire effectuée avant l'élaboration des fils. Le colorant utilisé est du type résistant à la lumière, aux liquides et à différents types de stérilisation. On pourra utiliser différents colorants qui accrochent parfaitement aux fibres synthétiques et en particulier au polypropylène.Such braids are tinted in mass and therefore present a great homogeneity in the dyeing. Polypropylene fibers are particularly suitable for mass dyeing, that is to say carried out before the development of son. The dye used is of the type resistant to light, liquids and different types sterilization. We can use different dyes that hang perfectly synthetic fibers and in particular polypropylene.

Comme vu précédemment, le morceau fibreux 2 est inséré de manière simple à l'intérieur d'une pipette de laboratoire, telle que celle représentée à la Fig. 1, après avoir été préalablement plié. L'ensemble est ensuite emballé puis stérilisé, par exemple à l'oxyde d'éthylène suivi de rinçage à l'air ou encore au rayonnement nucléaire.As seen above, the fibrous piece 2 is inserted in a simple way inside a laboratory pipette, such as that shown in FIG. 1 , after being previously folded. The assembly is then packaged and sterilized, for example with ethylene oxide followed by rinsing with air or with nuclear radiation.

Claims (11)

Pipette (1) de laboratoire constituée notamment d'un tube (3) transparent comportant une extrémité (4) de prélèvement d'un liquide et une extrémité (5) d'aspiration dans laquelle est inséré un morceau (2) de matière fibreuse d'une couleur correspondant au moins à une caractéristique de la pipette, notamment à son volume nominal, caractérisé en ce que le morceau (2) de matière fibreuse se présente sous la forme d'une tresse de fils de fibres synthétiques entrelacés, ladite tresse étant pliée de façon à ce que le pli (21 ) ainsi formé soit positionné vers l'intérieur de la pipette.Laboratory pipette ( 1 ) consisting in particular of a transparent tube ( 3 ) comprising a liquid extraction end ( 4 ) and a suction end ( 5 ) into which a piece ( 2 ) of fibrous material is inserted. a color corresponding at least to a characteristic of the pipette, in particular to its nominal volume, characterized in that the piece ( 2 ) of fibrous material is in the form of a braid of intertwined synthetic fiber yarns, said braid being folded so that the fold ( 2 1 ) thus formed is positioned towards the inside of the pipette. Pipette (1) de laboratoire selon la revendication 1, caractérisée en ce que la tresse présente un tressage d'occupation normale.Laboratory pipette ( 1 ) according to claim 1, characterized in that the braid has a braiding of normal occupation. Pipette (1) de laboratoire selon la revendication 1 ou 2, caractérisée en ce que la tresse comporte 4, 8 ou 16 fils entrelacés.Laboratory pipette ( 1 ) according to claim 1 or 2, characterized in that the braid comprises 4, 8 or 16 intertwined threads. Pipette (1) de laboratoire selon la revendication 1 à 3, caractérisée en ce que la tresse présente un poids au mètre linéaire compris entre 0,5 et 4,5 g/m.Laboratory pipette ( 1 ) according to claim 1 to 3, characterized in that the braid has a weight per linear meter of between 0.5 and 4.5 g / m. Pipette (1) de laboratoire selon la revendication 1 à 4, caractérisée en ce que la tresse est en polypropylène.Laboratory pipette ( 1 ) according to claim 1 to 4, characterized in that the braid is made of polypropylene. Procédé pour identifier au moins une caractéristique, et en particulier le volume nominal d'une pipette (1) de laboratoire constituée notamment d'un tube (3) transparent comportant une extrémité (4) de prélèvement d'un liquide et une extrémité (5) d'aspiration comprenant l'insertion d'un morceau (2) de matière fibreuse dont la couleur correspond à la caractéristique identifiable de la pipette (1),
   caractérisé en ce que l'on utilise en tant que morceau (2) de matière fibreuse, une tresse de fils de fibres synthétiques entrelacés, que l'on plie avant insertion et que l'on insère dans l'extrémité d'aspiration, de façon à ce que le pli ainsi formé soit positionné vers l'intérieur de la pipette.Process for identifying at least one characteristic, and in particular the nominal volume of a laboratory pipette ( 1 ) consisting in particular of a transparent tube ( 3 ) having a liquid-collecting end ( 4 ) and an end ( 5) ) comprising the insertion of a piece ( 2 ) of fibrous material whose color corresponds to the identifiable characteristic of the pipette ( 1 ),
characterized in that a plait of intertwined synthetic fiber yarns is used as piece ( 2 ) of fibrous material, which is folded before insertion and inserted into the suction end, so that the fold thus formed is positioned towards the inside of the pipette. Procédé selon la revendication 6, dans lequel la vitesse d'écoulement du liquide à prélever est régulée notamment par le choix du nombre de fils de la tresse et le poids au mètre linéaire de la tresse.The method of claim 6, wherein the flow rate of the the liquid to be sampled is regulated in particular by the choice of the number of threads of the braid and the weight per linear meter of the braid. Procédé selon la revendication 6 ou 7, caractérisé en ce que la tresse présente un tressage d'occupation normale. Process according to Claim 6 or 7, characterized in that the braid has normal occupation braiding. Procédé selon l'une des revendications 6 à 8, caractérisé en ce que la tresse comporte 4, 8 ou 16 fils entrelacés.Method according to one of Claims 6 to 8, characterized in that the braid comprises 4, 8 or 16 intertwined threads. Procédé selon l'une des revendications 6 à 9, caractérisé en ce que la tresse présente un poids au mètre linéaire comprise entre 0,5 et 4,5 g/m.Method according to one of claims 6 to 9, characterized in that the braid has a weight per linear meter of between 0.5 and 4.5 g / m. Procédé selon l'une des revendications 6 à 10, caractérisé en ce que la tresse est en polypropylène.Process according to one of Claims 6 to 10, characterized in that the braid is made of polypropylene.
EP03356150A 2002-10-16 2003-10-13 Pipette comprising a coloured braid of synthetic fibres for coding at least a characteristic of the pipette Expired - Lifetime EP1410845B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0212850 2002-10-16
FR0212850A FR2845933B1 (en) 2002-10-16 2002-10-16 LABORATORY PIPETTE COMPRISING A BRAID OF SYNTHETIC FIBER YARNS OF A COLOR CORRESPONDING TO AT LEAST ONE CHARACTERISTIC OF THE PIPETTE

Publications (3)

Publication Number Publication Date
EP1410845A2 true EP1410845A2 (en) 2004-04-21
EP1410845A3 EP1410845A3 (en) 2004-09-15
EP1410845B1 EP1410845B1 (en) 2010-04-14

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EP03356150A Expired - Lifetime EP1410845B1 (en) 2002-10-16 2003-10-13 Pipette comprising a coloured braid of synthetic fibres for coding at least a characteristic of the pipette

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US (1) US7007562B2 (en)
EP (1) EP1410845B1 (en)
CN (1) CN1304116C (en)
AT (1) ATE464122T1 (en)
DE (1) DE60332078D1 (en)
DK (1) DK1410845T3 (en)
ES (1) ES2344635T3 (en)
FR (1) FR2845933B1 (en)
HK (1) HK1063751A1 (en)

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EP3344393A4 (en) * 2015-09-03 2019-04-03 Vistalab Technologies, Inc. Low insertion force, low wobble serological pipet

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US7794664B2 (en) 2006-11-16 2010-09-14 Idexx Laboratories, Inc. Pipette tip
US8517219B1 (en) * 2009-07-23 2013-08-27 Frenchette Chatman Prince Measuring device and method to use it
CN102847570A (en) * 2012-08-29 2013-01-02 浙江硕华医用塑料有限公司 Disposable pipet
CH718088A1 (en) * 2020-11-24 2022-05-31 Integra Biosciences Ag Pipette and pipette controller with 2-character coding.

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WO1996017673A1 (en) * 1994-12-07 1996-06-13 Fsm Technologies Limited Micro-filtration device
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EP3344393A4 (en) * 2015-09-03 2019-04-03 Vistalab Technologies, Inc. Low insertion force, low wobble serological pipet

Also Published As

Publication number Publication date
DK1410845T3 (en) 2010-07-26
FR2845933A1 (en) 2004-04-23
FR2845933B1 (en) 2005-02-11
DE60332078D1 (en) 2010-05-27
ATE464122T1 (en) 2010-04-15
CN1496759A (en) 2004-05-19
EP1410845A3 (en) 2004-09-15
ES2344635T3 (en) 2010-09-02
EP1410845B1 (en) 2010-04-14
CN1304116C (en) 2007-03-14
US7007562B2 (en) 2006-03-07
US20040123680A1 (en) 2004-07-01
HK1063751A1 (en) 2005-01-14

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