EP0831793A4 - Protein particles for therapeutic and diagnostic use - Google Patents
Protein particles for therapeutic and diagnostic useInfo
- Publication number
- EP0831793A4 EP0831793A4 EP96918313A EP96918313A EP0831793A4 EP 0831793 A4 EP0831793 A4 EP 0831793A4 EP 96918313 A EP96918313 A EP 96918313A EP 96918313 A EP96918313 A EP 96918313A EP 0831793 A4 EP0831793 A4 EP 0831793A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- therapeutic
- diagnostic use
- protein particles
- protein
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/471,650 US5725804A (en) | 1991-01-15 | 1995-06-06 | Non-crosslinked protein particles for therapeutic and diagnostic use |
US471650 | 1995-06-06 | ||
US55491995A | 1995-11-09 | 1995-11-09 | |
US554919 | 1995-11-09 | ||
PCT/US1996/009458 WO1996039128A1 (en) | 1995-06-06 | 1996-06-04 | Protein particles for therapeutic and diagnostic use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0831793A1 EP0831793A1 (en) | 1998-04-01 |
EP0831793A4 true EP0831793A4 (en) | 2000-11-15 |
Family
ID=27043520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96918313A Withdrawn EP0831793A4 (en) | 1995-06-06 | 1996-06-04 | Protein particles for therapeutic and diagnostic use |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0831793A4 (en) |
JP (1) | JPH11507630A (en) |
AU (1) | AU6100296A (en) |
CA (1) | CA2220895A1 (en) |
WO (1) | WO1996039128A1 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2269335C (en) * | 1996-10-21 | 2010-05-25 | Quadrant Healthcare (Uk) Limited | Platelet substitutes and conjugation methods suitable for their preparation |
EP0860167A1 (en) * | 1997-01-30 | 1998-08-26 | Robert Gurny | RNA-and DNA- based active agents in nanoparticles |
CA2294494A1 (en) * | 1997-06-05 | 1998-12-10 | Richard C. K. Yen | Fibrinogen-coated microspheres |
GB9724143D0 (en) | 1997-11-14 | 1998-01-14 | Andaris Ltd | Pharmaceutical conjugate |
US6514500B1 (en) | 1999-10-15 | 2003-02-04 | Conjuchem, Inc. | Long lasting synthetic glucagon like peptide {GLP-!} |
US6444226B1 (en) * | 1999-06-29 | 2002-09-03 | Pharmaceutical Discovery Corporation | Purification and stabilization of peptide and protein pharmaceutical agents |
US20090280534A1 (en) * | 2004-12-22 | 2009-11-12 | Novozymes A/S | Recombinant Production of Serum Albumin |
JPWO2007020871A1 (en) * | 2005-08-12 | 2009-02-26 | アステラス製薬株式会社 | Depsipeptide-containing injection solution |
DE102006011507A1 (en) | 2006-03-14 | 2007-09-20 | Lts Lohmann Therapie-Systeme Ag | Active substance-loaded nanoparticles based on hydrophilic proteins |
GB0623607D0 (en) | 2006-11-27 | 2007-01-03 | Haemostatix Ltd | Tissue adhesive |
US10603287B2 (en) * | 2016-07-20 | 2020-03-31 | Ptlnv, Llc, Series Three (3) | Albumin nanosphere preparations to control bleeding from surgical operations |
US9504641B2 (en) * | 2011-09-10 | 2016-11-29 | Richard C. K. Yen | Therapy to reduce extravasation damage |
KR101167285B1 (en) * | 2011-11-18 | 2012-07-23 | 에이앤펩주식회사 | Niacin-peptides having skin whitening effect and uses thereof |
CN110139662B (en) | 2017-07-05 | 2022-03-18 | 江阴贝瑞森制药有限公司 | Anti-inflammatory use of peptides |
MA52794A (en) * | 2018-05-28 | 2021-04-14 | Jiangyin Usun Pharmaceutical Co Ltd | NEW PHARMACEUTICAL USE |
CN113797861B (en) * | 2021-09-16 | 2024-03-29 | 江苏月旭新材料科技有限公司 | Hydroxypropyl glucan microsphere and preparation method and application thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
US4147767A (en) * | 1975-10-09 | 1979-04-03 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
US4925677A (en) * | 1988-08-31 | 1990-05-15 | Theratech, Inc. | Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3565559A (en) * | 1968-03-11 | 1971-02-23 | Sumitomo Chemical Co | Process for making microcapsules |
US4325937A (en) * | 1977-09-22 | 1982-04-20 | Battelle Development Corporation | Microbial insecticide |
CH652599A5 (en) * | 1981-08-28 | 1985-11-29 | Solco Basel Ag | Method for producing colloidal physiological degradable, human serum albumin containing products and their use. |
US4818542A (en) * | 1983-11-14 | 1989-04-04 | The University Of Kentucky Research Foundation | Porous microspheres for drug delivery and methods for making same |
US5104674A (en) * | 1983-12-30 | 1992-04-14 | Kraft General Foods, Inc. | Microfragmented ionic polysaccharide/protein complex dispersions |
SE459005B (en) * | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | SET TO MANUFACTURE SPHERICAL POLYMER PARTICLES |
US5069936A (en) * | 1987-06-25 | 1991-12-03 | Yen Richard C K | Manufacturing protein microspheres |
JPS6418439A (en) * | 1987-07-14 | 1989-01-23 | Nippon Oils & Fats Co Ltd | Powdery fat coated with crosslinked coating and its manufacture |
JPH0813750B2 (en) * | 1990-03-01 | 1996-02-14 | 持田製薬株式会社 | Oral thrombin formulation |
US5374441A (en) * | 1992-02-04 | 1994-12-20 | Rutgers, The State University Of New Jersey | Heat stable fat substitute compositions and process |
-
1996
- 1996-06-04 EP EP96918313A patent/EP0831793A4/en not_active Withdrawn
- 1996-06-04 CA CA002220895A patent/CA2220895A1/en not_active Abandoned
- 1996-06-04 JP JP9501772A patent/JPH11507630A/en active Pending
- 1996-06-04 WO PCT/US1996/009458 patent/WO1996039128A1/en not_active Application Discontinuation
- 1996-06-04 AU AU61002/96A patent/AU6100296A/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
US4147767A (en) * | 1975-10-09 | 1979-04-03 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
US4925677A (en) * | 1988-08-31 | 1990-05-15 | Theratech, Inc. | Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents |
Non-Patent Citations (1)
Title |
---|
See also references of WO9639128A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU6100296A (en) | 1996-12-24 |
JPH11507630A (en) | 1999-07-06 |
CA2220895A1 (en) | 1996-12-12 |
WO1996039128A1 (en) | 1996-12-12 |
EP0831793A1 (en) | 1998-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 19971224 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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AX | Request for extension of the european patent |
Free format text: AL PAYMENT 971224;LT PAYMENT 971224;LV PAYMENT 971224;SI PAYMENT 971224 |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20000928 |
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Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7A 61K 9/64 A, 7A 61K 31/74 B, 7A 61K 38/38 B, 7B 01J 13/02 B, 7A 61K 9/16 B, 7A 61K 38/36 B, 7A 61K 9/51 B |
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17Q | First examination report despatched |
Effective date: 20020423 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20020903 |