EP0804155B1 - Composition and method for enhancing transdermal electrotransport agent delivery - Google Patents

Composition and method for enhancing transdermal electrotransport agent delivery Download PDF

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Publication number
EP0804155B1
EP0804155B1 EP95925470A EP95925470A EP0804155B1 EP 0804155 B1 EP0804155 B1 EP 0804155B1 EP 95925470 A EP95925470 A EP 95925470A EP 95925470 A EP95925470 A EP 95925470A EP 0804155 B1 EP0804155 B1 EP 0804155B1
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EP
European Patent Office
Prior art keywords
electrotransport
agent
enhancer
enhancers
donor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP95925470A
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German (de)
English (en)
French (fr)
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EP0804155A1 (en
Inventor
J.Richard Gyory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
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Alza Corp
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Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of EP0804155A1 publication Critical patent/EP0804155A1/en
Application granted granted Critical
Publication of EP0804155B1 publication Critical patent/EP0804155B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
EP95925470A 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery Expired - Lifetime EP0804155B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US274619 1981-06-17
US27461994A 1994-07-13 1994-07-13
PCT/US1995/008384 WO1996002232A1 (en) 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery

Publications (2)

Publication Number Publication Date
EP0804155A1 EP0804155A1 (en) 1997-11-05
EP0804155B1 true EP0804155B1 (en) 2000-11-08

Family

ID=23048961

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95925470A Expired - Lifetime EP0804155B1 (en) 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery

Country Status (7)

Country Link
US (1) US5668170A (un)
EP (1) EP0804155B1 (un)
JP (2) JP4090072B2 (un)
AT (1) ATE197396T1 (un)
DE (1) DE69519393T2 (un)
ES (1) ES2153485T3 (un)
WO (1) WO1996002232A1 (un)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
US9468682B2 (en) 2013-04-05 2016-10-18 Joint-stock company “High Tech” Compositions and methods for enhancing penetration of biologically active substances into tissues or organs

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AU4129696A (en) * 1994-11-17 1996-06-17 Alza Corporation Composition and method for enhancing electrotransport agent delivery
JPH11503043A (ja) * 1995-04-07 1999-03-23 ノバルティス・アクチエンゲゼルシャフト 少なくとも２種の被投与物を投与するためのイオン泳動性経皮システム
US5985316A (en) * 1995-04-28 1999-11-16 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5676648A (en) 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
CN1108173C (zh) * 1996-06-12 2003-05-14 阿尔萨公司 含有多元阴离子抗衡离子的治疗剂的改良电转运
US6004577A (en) * 1997-08-12 1999-12-21 Murdock; Thomas O. Enhanced electrotransport of therapeutic agents having polybasic anionic counter ions
US6775569B2 (en) 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
US6374136B1 (en) * 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
KR20010042875A (ko) * 1998-04-21 2001-05-25 엥펙시오 르쉐르쉬 엥꼬르뽀라시옹 폴록사머 및 추가의 살미생물제를 함유하는 국소용 조성물및 어플리케이터
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6347246B1 (en) * 2000-02-03 2002-02-12 Axelgaard Manufacturing Company, Ltd. Electrotransport adhesive for iontophoresis device
US6522918B1 (en) 2000-02-09 2003-02-18 William E. Crisp Electrolytic device
EP1307182B1 (fr) * 2000-08-01 2005-03-30 Sanofi-Aventis Composition pharmaceutique pour administration transdermique de befloxatone
US7465295B2 (en) * 2000-10-20 2008-12-16 Bergeron Michel G Applicator for the delivery of topical formulations into mucosal cavities
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
EP1440707A4 (en) * 2001-10-31 2006-05-24 Transcutaneous Tech Inc IONOPHORESIS DEVICE
CA2500713C (en) * 2002-10-04 2012-07-03 Photokinetix, Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
EP1633431B1 (en) * 2003-06-02 2008-11-12 Power Paper Ltd. Kit, device and method for controlled delivery of oxidizing agent into the skin
JP4728631B2 (ja) * 2004-11-30 2011-07-20 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US7590444B2 (en) * 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
JP4731931B2 (ja) * 2005-02-03 2011-07-27 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
RU2008114490A (ru) 2005-09-15 2009-10-20 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Устройство ионтофореза стержневого типа
JP2009509657A (ja) 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
WO2007041526A2 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
US7848801B2 (en) 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
DE602007009377D1 (de) 2006-05-30 2010-11-04 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
KR101200728B1 (ko) 2006-08-09 2012-11-13 인타르시아 세라퓨틱스 인코포레이티드 삼투성 전달 시스템 및 피스톤 조립체
JPWO2008087803A1 (ja) * 2007-01-16 2010-05-06 国立大学法人北海道大学 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
AU2008244523B2 (en) 2007-04-23 2012-02-16 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
KR101674904B1 (ko) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 중재형 약물전달 시스템과 그 방법
SI2462246T1 (en) 2009-09-28 2018-01-31 Intarcia Therapeutics, Inc. Fast-setting and / or cessation of substantially unchanged delivery of the product
WO2011046927A1 (en) * 2009-10-13 2011-04-21 Nupathe,Inc. Transdermal methods and systems for the delivery of rizatriptan
US9237961B2 (en) * 2010-04-23 2016-01-19 Medtronic Vascular, Inc. Stent delivery system for detecting wall apposition of the stent during deployment
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
KR20240042548A (ko) 2015-06-03 2024-04-02 인타르시아 세라퓨틱스 인코포레이티드 임플란트 배치 및 제거 시스템들
MA53353A (fr) 2016-05-16 2021-06-09 Intarcia Therapeutics Inc Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
EP3565580B1 (en) 2017-01-03 2024-03-06 i2o Therapeutics, Inc. Continuous administration of exenatide and co-adminstration of acetaminophen, ethinylestradiol or levonorgestrel
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1992000077A1 (en) * 1990-06-28 1992-01-09 Medicis Corporation Improved ointment base and method of use

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US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
US4690683A (en) * 1985-07-02 1987-09-01 Rutgers, The State University Of New Jersey Transdermal varapamil delivery device
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4992477A (en) * 1988-04-04 1991-02-12 Warner-Lambert Company Skin moisturizing composition and method of preparing same
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
NZ237489A (en) * 1990-04-18 1995-07-26 Alza Corp Device for electrotransport and reservoir therefor containing a fatty acid as permeation enhancing agent
ATE169826T1 (de) * 1992-01-21 1998-09-15 Macrochem Corp Iontophoretische verbesserte verabreichung von medikamenten
JPH0616538A (ja) * 1992-07-03 1994-01-25 Japan Tobacco Inc イオントフォレーゼのための薬物吸収用液組成物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000077A1 (en) * 1990-06-28 1992-01-09 Medicis Corporation Improved ointment base and method of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 9205, Derwent World Patents Index; Class A82 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
US9468682B2 (en) 2013-04-05 2016-10-18 Joint-stock company “High Tech” Compositions and methods for enhancing penetration of biologically active substances into tissues or organs

Also Published As

Publication number Publication date
DE69519393D1 (de) 2000-12-14
ATE197396T1 (de) 2000-11-11
EP0804155A1 (en) 1997-11-05
ES2153485T3 (es) 2001-03-01
DE69519393T2 (de) 2001-04-26
JP2007314562A (ja) 2007-12-06
US5668170A (en) 1997-09-16
WO1996002232A1 (en) 1996-02-01
JP4090072B2 (ja) 2008-05-28
JPH10503184A (ja) 1998-03-24

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