EP0570496A4 - Polymorphic dna markers in bovidae - Google Patents

Abstract

Described is a collection of bovine genomic clones that map to polymorphic loci in bovids. Said clones will find utility in genetic identification, gene mapping and selective breeding.

Description

TITLE OF THE INVENTION POLYMORPHIC DNA MARKERS IN BOVID.AE

CROSS-REFERENCE TO RELATED APPLICATIONS

The present invention is a continuation-in-part of U.S. Ser. No. 642,342, filed January 15, 1991, incorpo¬ rated herein by reference.

FIELD OF THE INVENTION

The invention relates to gene mapping, selective breeding and genetic identification in domestic animals.

BACKGROUND OF THE INVENTION

The publications and other materials used herein to illuminate the background of the invention, and in particular, cases to provide additional details respect¬ ing the practice, are incorporated by reference and for convenience are numerically referenced in the following text and respectively grouped in the appended bibliog¬ raphy.

Until recently, artificial selection has relied on the biometrical evaluation of individual breeding values from an animal's own performance and from performance of its relatives (136) . This biometrical strategy is based on relatively simple genetic premises, operating within a "black box". Briefly, the majority of economically important traits are so-called complex or quantitative traits, meaning that the phenotype of an animal is determined by both environment and a large number of genes with individually small, additive effects. The proportion of the phenotypic variation observed in a given population that is genetic in nature is the heritability of the trait. Substantial genetic progress has been obtained using this approach. One of the powers of this biometrical approach is that it obviates the need for any detailed molecular knowledge of the underlying genes or Economic Trait Loci.

However, it is believed that the molecular identification of these Economic Trait Loci could increase genetic response by affecting both time and accuracy of selection, through a procedure called Marker Assisted Selection (91, 96) . One strategy towards the isolation of Economic Trait Loci relies on the use of DNA Sequence Polymorphisms as genetic markers in linkage studies. This approach, paradoxically referred to as "Reverse Genetics" (138) , will be described in detail in this introduction. Moreover, we propose a new concept called "Velogenetics", or the combined use of Marker Assisted Introgression and germ-line manipulations to shorten the generation interval of domestic species (especially cattle) , which will allow the rapid and efficient introgression of mapped Economic Trait Loci between genetic backgrounds.

I. DNA SEQUENCE POLYMORPHISM (DSP)

A. Types of DNA Sequence Polymorphism

The typical mammalian genome is composed of an approximately 3xl0⁹ base pairs long DNA stretch, divided over a species-specific number of chromosomes, and containing all the information required for the proper development and functioning of a normal being. Each individual has two copies of this message: one paternal in origin and one maternal. Although their overall architecture and content are virtually identical, the paternal and maternal DNA sequences exhibit subtle "allelic" differences, hereinafter referred to as DNA Sequence Polymorphisms or "DSP". The DSP that can be recognized in a given population are the molecular basis of the genetic component of the observed phenotypic variance. One can distinguish three types of DSP. 1. Single Base Pair Polymorphisms

As their name implies, these DSP are due to single base pair differences distinguishing alleles. These can be either base pair substitutions - transitions (Purine to Purine or Pyrimidine to Pyrimidine) and transversions (Purine to Pyrimidine and vice versa) -, or the inser¬ tion/deletion of a single base pair.

The frequency of single base pair polymorphism is measured by the nucleotide diversity, π , or average heterozygosity per nucleotide site (1) . The nucleotide diversity has been estimated from Restriction Fragment Length Polymorphisms at 0.002 for human (2), and at 0.0007 in cattle (3,4). This means that on the average a human will be heterozygous for one every 500 nucleo- tides, and a cow for one every 1,500 nucleotides.

One type of single base pair polymorphism deserves special attention: the CpG to TpG transition. The cytosine in the CpG dinucleotide sequence is known to be the substrate of an eucaryotic methylase, which will add a methyl group in position 5 of the pyrimidine ring, if the cytosine of the complementary CpG dinucleotide is itself methylated. Deamination of a 5-methylcytosine generates a thymine, blurring the task of the DNA repair machinery which will half of the time resolve the ensuing mismatch by replacing the original guanine instead of the mutated thymine. As a consequence, cyto- sines in the CpG doublet exhibit mutation rates at least ten times higher than other nucleotides, and hence are rich sources of single base pair polymorphisms (4, 5).

2. DNA Sequence Rearrangements

In this kind of DSP, the difference between allelic variants involves DNA sequence rearrangements such as the insertion or deletion of a stretch of DNA, DNA sequence inversions and duplications. Although there is a wide spectrum of molecular mechanisms susceptible to generate such chromosomal re- arrangements, it is well established that mobile genetic elements significantly contribute to this kind of DSP. In lower eukaryotes such as Drosophila and yeast, rearrangements involving transposable elements account for a large proportion of new mutations detected in these organisms (6) . In the mouse, retrovirus-like sequences or retrotransposons have been shown to act as insertional utagens (7-11) , and different strains of mice exhibit substantial heterogeneity with respect to the numbers and chromosomal sites of endogenous pro- viruses (12) . Variation in the distribution of endoge¬ nous retroviruses has been demonstrated in poultry as well.

In the human, at least 10% of the genome is known to be composed of retroposon-like sequences. Evidence for a role of these sequences in human genetic varia¬ bility and disease stems from several reports of de novo mutations due to these sequences: a mutation in the human Low Density Lipoprotein receptor gene giving rise to familial hypercholesterolemia is caused by a deletion brought about by an intrastrand recombination event between two Alu sequences (13) ; LI insertions were found to inactivate the factor VIII gene in hemophilia A patients (14) ; a c-myc rearrangement in a breast carcin- oma was found to be due to insertion of an LI element (15) ; an Alu transposition event has been documented in human lung carcinoma cells (16) ; and an homologous recombination between the LTRs of a human retrovirus- like element was shown to cause a 5 Kb deletion poly- morphis . Recently, Wong et al. (17) reported evidence of human DNA polymorphism arising through DNA-mediated, rather than RNA-mediated, transfer between autosomes as well.

3. Expansion-Contraction Type Polymorphism A significant proportion of the eucaryotic genome is composed of sequences widely termed "satellite DNA," sharing a common organization: a sequence motif, varying in length between one and several thousand nucleotides, repeated in a head-to-tail or so-called tandem arrange¬ ment. Depending on the methodology originally used for their study, i.e. isopycnic centrifugation, pulsed field gel electrophoresis, agarose gel electrophoresis or polyacrylamide gel electrophoresis, satellite sequences were grouped into four size classes: macro-, midi-, mini- and micro-satellites. Minisatellites are also known as Variable Number of Tandem Repeats (VNTRs) (18- 21) . While macro-satellites seem to be confined to heterochromatic regions (22) , mini- and micro-satellites have been found scattered throughout the genome with, however, clustering of mini-satellites (23-34) . In the human, minisatellite clusters seems to be particularly abundant in proterminal regions (35) . The only midi- satellite described as such today, has been mapped to the short arm of chromosome 1 (36) . In the human, the polydeoxyadenylate tract of Alu repetitive elements are also caracterized by length variation and are thus an abundant source of genetic markers as well (37) .

The function, if any, of satellite sequences, whether macro-, midi-, mini- or micro-, is essentially unknown. An important feature of all satellite sequences is that the maintenance of their tandemly repeated organization is dependent on the concerted evolution of the repeats. This concerted evolution is thought to result from subsequent rounds of unequal crossing-over (or any other mechanisms fitting the "card deck" model (38)), which are favored by the tandemly repeated structure itself. The proposed unequal crossing-over mechanism, whether happening between sister chromatids or homologous chromosomes, explains the substantial degree of length polymorphism, here referred to as "expansion-contraction polymorphism," characterizing those sequences. Moreover, the ensuing shuffling of slightly divergent repeat units or Minisatellite Variant Repeats (39) within the satellite generates additional internal site polymorphism. These peculiar properties of satellite sequences have made them an invaluable source of highly informative genetic markers, both in the human and in domestic species (reviewed in 31) .

B. Detection of DNA Sequence Polymorphism

During the last ten years, a multitude of methods have been developed for the detection of DSP. Two techniques, however, undoubtedly dominate this field: Southern blot hybridization (40) and the Polymerase Chain Reaction or PCR (41) , used either separately or in conjunction. A non-exhaustive list is reported here, the methods being grouped into four classes.

1. Restriction Pattern Analysis DSP may alter the restriction patterns of defined chromosomal regions, generating so-called Restriction Fragment Length Polymorphisms (RFLP) . Depending on the size-range of the explored restriction fragments, one will use either agarose gel electrophoresis, pulse-field gel electrophoresis (30) or polyacrylamide gel electrophoresis (42) for intermediate, large or small fragments respectively. RFLPs are classically detected by Southern blot hybridization. Alternatively, one can analyze restriction patterns of defined DNA sequences amplified by PCR, generating so-called Amplified Sequence Polymorphisms (43) . When studying chromosomal rearrangements or expansion-contraction type polymorph¬ isms, the use of PCR obviates the need for restriction enzyme digestion, the DSP reflecting itself in the size of the amplified product.

Because of its simplicity, the detection of RFLPs has by far been the most popular approach towards DSP. The relative lack of power inherent to the method (only 20% of a given sequence is amenable to exploration using the most common restriction enzymes) can be compensated for by focusing on highly polymorphic sequences such as CpG dinucleotides (using enzymes such as TaqI and Mspl containing CpG in their recognition sequence) or hyper- variable minisatellites. The discovery, however, of microsatellites as a very abundant source of highly informative DSP in a broad taxono ic range, easily detectable by PCR, is likely to shift the focus towards these sequences for future marker development (32-34, 37, 44).

2. Mismatch Analysis

Several methods for the detection of DSP are based on the study of mismatch analysis. DNA to analyze is probed with a sequence corresponding to a defined genetic variant. The presence of a different variant in the target DNA generates a mismatched heteroduplex, which can be detected by various means:

a. Detection of Altered Melting Behavior A mismatched heteroduplex will differentiate itself from the perfectly matched homoduplex by an altered melting behavior which can be detected as an all-or- none, binary response: positive for the homoduplex, negative for the heteroduplex, or in a more graded response, allowing to distinguish between different heteroduplex variants. The classical all-or-none test depends on the use of allele-specific oligonucleotides in hybridization experiments. By choosing appropriate hybridization and washing conditions, the allele-specific oligonucleotide will only recognize a perfectly complementary sequence (45) . With the advent of PCR, new variants of this approach have been described including reverse dot-blot (46) , the Amplification Refractory Mutation System (47) or allele-specific polymerase chain reaction (48) , and Competitive Oligonucleotide Priming (49) . The Ligation Amplification Reaction, amplification of specific DNA sequences using sequential rounds of template-dependent ligation, can also be considered as a peculiar applica¬ tion of the allele-specific oligonucleotide approach (50). More discriminating is Denaturing Gradient Gel Elec¬ trophoresis, exploring the pattern of melting behavior characterizing each heteroduplex when electrophoresed through an increasing gradient of DNA denaturants (51) . The sensitivity of this method can also be improved by pre-amplifying the target sequence by PCR.

b. Ribonuclease and chemical mismatch detection The presence of a mismatch in a heteroduplex makes those molecules susceptible to cleavage by various means including chemical treatment with either hydroxylamine or osmium tetroxide (52) , as well as ribonucleases such as RNase A in case of an RNA:DNA heteroduplex (51) . Electrophoretic analysis of the cleavage products allows one to distinguish different genetic variants. Again, implementing PCR will increase the sensitivity of the approach.

3. Single Stranded Conformation Polymorphism Under nondenaturing conditions, single-stranded DNA has a folded conformation that is stabilized by intra- strand interactions. Consequently, the conformation, and therefore the electrophoretic mobility, is dependent on the sequence. DNA variants exhibit indeed mobility shifts when electrophoresed in such conditions, presum¬ ably resulting from conformational changes caused by sequence alterations, hence the name single stranded conformation polymorphism. Again, the altered mobility can be detected by blot hybridization analysis or rely¬ ing on PCR (53, 54). 4. Direct Determination of the DNA Sequence Obviously the most powerful approach towards DSP is the direct determination of the DNA sequence. The need of a cloning step, however, in classical sequencing pro- tocols precluded the analysis of large samples. This limitation has been circumvented by the development of genomic sequencing (55) , allowing the direct determina¬ tion of defined DNA sequences from genomic DNA, and more recently and less laboriously by the development of direct sequence determination of PCR amplified products. The feasibility of the latter approach for the detection of DSP has been amply demonstrated in several independ¬ ent studies (see, for instance, 56) .

C. Origin and Evolution of DNA Sequence Polymorphism DSP encountered in a given population find their origin in mutational events occurring in the germline and escaping the DNA repair machinery. The fate of these germline mutations in the population is dominated by two kinds of effects: stochastic and deterministic effects.

1. Stochastic Effects

When a new mutation appears in the population, its initial survival depends largely on chance, regardless of its selective effect. This is easily illustrated as follows. Assume an individual heterozygous for a neo- mutation inherited from its parent, in whose germline the mutation appeared. If this individual has one, two or three offspring, the chances for the neomutation to be lost from the population, because transmitted to none of the offspring, are 0.5, 0.25 and 0.125 respectively. Even if inherited by part of the offspring, the same "stochastic filter" will operate in the next generation. In the course of this random drift, the overwhelming majority of mutant alleles are lost by chance. However, some will see their frequency increase in the population, and despite fluctuations over time, eventually become fixed in the population, until substituted by the next mutant allele.

As demonstrated essentially by Kimura (57) in the framework of his neutral theory of molecular evolution, the probability for a selectively neutral neomutation to be fixed in a population of N individuals is equal to its initial frequency 1/2N, the average time for fixation is four times the "effective" population size or 4Ne, and the rate k of mutant substitution per generation is simply equal to the rate of mutation per gamete and per generation, μ, independent of what the population size may be.

According to this view, a polymorphism observed in a population at a given time is composed of "transient" alleles catched in their stochastic "odyssey" throughout the population.

Populations for which 4.Ne.μ < 1 are essentially monomorphic, while populations for which 4.Ne.μ « 1 are characterized by a substantial degree of transient polymorphism. The model predicts a steady state level of heterozygosity, H:

4.Ne.μ

H 4.Ne.μ + 1

2. Deterministic Effects

There is evidence that the fate of a significant proportion of DSP, especially those occurring in non- coding parts of the genome (composing the large majority of the genome) , is essentially dominated by random drift. However, when a neo-mutation affects a DNA sequence which is expressed at the phenotypic level in the broad sense, the mutation may not longer be selec¬ tively neutral, and deterministic effects will be superimposed on the stochastic ones. Negative and positive selection will respectively decrease or increase the probability and rate of fixation, while "balancing selection" will maintain specific alleles in a population in an equilibrium state.

a. Negative Selection When comparing DNA sequences between taxa, it appears that the estimated number of mutant substi¬ tutions per nucleotide to account for the observed divergence is highest for non-coding sequences, such as pseudogenes and intronic sequences, and much lower for coding sequences. For the latter, however, a difference must be made between first, second and third positions of the codons. The third position, for which only 28% of substitutions are expected to cause an amino acid change (versus 95% and 100% for first and second positions respectively) , exhibits the highest substitu¬ tion rate. When estimating that part of substitutions at the third positions which are so-called synonymous, rates very similar to non-coding regions are observed (57) . Moreover, DSP are more prominent for non-coding sequences and, within coding sequences, at third codon positions (compared to first and second positions (58)) . These observations are easily explained by assuming that the fate of neomutations arising in non-coding regions or of synonymous neomutations, is dominated by stochas- tic effects, while the fate of mutations causing amino acid replacements will depend as well on whether or not they disrupt the function of the protein, in which case they will be eliminated from the population by negative, "purifying" selection. The higher the functional con- straints imposed on a protein, the higher the proportion of neomutations expected to be harmful and, hence, the lower the substitution rate, expressed at the protein level as a higher "unit evolutionary time" (average time required for one amino acid change to appear in a sequence of 100 amino acid residues) . These observations have been considered as a strong argument in favor of a predominant role for random drift in the dynamics of molecular evolution.

b. Positive selection According to the previous discussion, the major drive behind molecular evolution is non-adaptive in nature, which is in conflict with the classical theory of adaptive, positive Darwinian selection.

There is, however, evidence for positive and adaptive evolution at the molecular level in at least a few instances. Comparing DNA sequences from members of two gene families: the serine protease inhibitors in rat

(59) and the pregnancy specific βl glycoprotein gene family in man, evidence has been found for higher substitution rates at first and second codon positions than at the third position, in at least some protein regions, pointing towards positive selection.

Moreover, there are a number of experimental data suggesting that some allelic differences identified by electrophoresis are associated with adaptation to different environments. In Drosophila, for instance, their is evidence for correlation between in vitro heat resistance of ADH variants and the temperature charac¬ terizing their geographical origin (58) .

c. Balancing selection

The evolutionary forces described so far generate transient DSP in the sense that the population fre¬ quencies of existing genetic variants will irrevocably change with time until either fixation or loss. In some cases, however, alleles may be maintained in a popula¬ tion at a steady state level. Overdominance is one of the mechanisms susceptible to generate such a "balanced polymorphism". For a two allele system, this means that the heterozygous individuals benefit from a selective advantage compared to both homozygous genotypes. This is expected to generate a steady state where both alleles are maintained in the population at respective equilibrium frequencies p and q, where

and p = s + t s + t

s and t being the respective selection coefficients of the homozygotes.

The best known example of balanced polymorphism due to overdominance is the maintenance of the S α-globin allele (causing sickle-cell anemia in the homozygotes) as well as thalassemia-causing mutants (see, for instance, 61) in populations subjected to malaria, because of the resistance exhibited by the heterozygotes towards the parasite. The high level of polymorphism observed at the Major Histocompatibility Locus is thought to result from overdominance selection as well (62).

Frequency dependent selection may be another cause of balanced polymorphism, an example being the "rare mate advantage" observed in Drosophila (63) .

II. CONSTRUCTION OF PRIMARY DNA MARKER MAPS

A. Linkage Strategies

Two loci are said to be genetically linked if, during meiosis, they recombine at significantly lower than a 50% rate, i.e., they generate significantly more parental gametes than recombinant gametes. The recom¬ bination rate between loci reflects the frequency of occurrence of an uneven number of crossing-overs between the loci. Because the probability for crossing-over is proportional to the distance separating the loci, the recombination rate can be used as a unit of chromosomal length. This length unit is known as the Morgan (M) , 1 cM corresponding to the distance separating two loci exhibiting a 1% recombination rate. For small distance (<30cM) , the relation between centimorgan and recombin¬ ation rate is essentially linear. For longer distances, however, the relation is more complex, depending on the frequency of double crossing-overs, itself affected by eventual interference.

Parental and recombinant gametes will only be distinguishable for doubly heterozygous individuals, hence the need for highly polymorphic markers.

Recently, and due to the advent of the PCR, it has been possible to directly determine the genotype of individual gametes (64) . However, most of the time, the gametic contribution is inferred from the genotype of the offspring and linkage studies are performed within families. Most modern linkage studies use the lodscore test for evaluation of linkage: a sequential test based on the method of maximum likelihood (65) . The lodscore corresponds to loglO(LR), where LR corresponds to the ratio: likelihood of observations under alternative hypothesis θ<0.5, divided by the likelihood of observ¬ ations under null hypothesis of no linkage, θ=0.5. In human genetics, a lodscore > 3 is accepted as signif¬ icant evidence for linkage. The prior probability of linkage between two loci has been used to justify this stringent critical value. Note that 21n(LR) can be used as well, having a chi-square distribution with one degree-of-freedom under the null hypothesis of no linkage. Recently, algorithms for multilocus linkage analy¬ sis have been developed, allowing an estimate of the most likely gene orders and genetic distances between several loci simultaneously (66-68) .

Although usually determined within families, genetic linkage can manifest itself at the population level also: a phenomenon called "linkage disequilib¬ rium". According to the Hardy-Weinberg law, the equilibrium genotypic frequencies are reached in a single generation (except if the initial gene frequen¬ cies are not equal among sexes) . For a diallelic system with alleles al and a2, with respective allelic frequen- cies pi and p2, the equilibrium genotypic frequencies are pi², 2plp2 and p2² for alal, ala2 and a2a2 respec¬ tively. This does not necessarily hold when considering two loci simultaneously. The genotypic equilibrium frequencies are only reached when the previous genera- tion produces the four possible gametes at the expected frequencies: albl: plql, a2bl: p2ql, albl: p2ql, a2b2: p2q2. The difference between observed and expected gametic frequencies is called linkage disequilibrium, D. The value of D is reduced by d.θ every generation, θ being the recombination rate between the two loci. For unlinked loci D diminishes by 1/2 every generation; for linked loci, however, the reduction of D per generation will be much smaller. The detection of a linkage disequilibrium is an indication of linkage between the corresponding loci.

B. Genetic Maps

Using this linkage approach, combined with alterna¬ tive mapping strategies such as "in situ" hybridization (see, for instance, 69) , the use of somatic cell hybrid panels and radiation hybrid mapping (reviewed in 70) and comparative mapping (71) , the map location of a large set of DSP can be determined in order to build a genetic marker map (see, for instance, 72-74) . Assuming a total map length of 30M as for the human, and a desirable maximum distance of 20cM between markers, a set of 150 DSP could cover the entire genome. However, many more markers will be needed to generate reasonable maps for our domestic species, essentially for two reasons. First, most of the time we have no a priori information on the location of the characterized markers. Hence, some chromosomal regions will initially be overrepresented in our map, others underrepresented. This problem is expected to become critical in the later stages of the development of a map. Comparative data will then become critical, allowing to search for markers whose location can be predicted from other species. Second, an individual will only be informative for the markers for which he is heterozygous; parts of his genome will thus not be explorable, because he will be homozygous for the corresponding markers. To compen- sate for this, one will have to identify more markers, the number required being inversely proportional to their heterozygosity — hence, the importance of highly informative systems.

Once such a map is available, however, any gene for which the appropriate segregating family material is available can be located on the map. Assuming a maximum marker-target gene distance of lOcM, the expected lodscore for doubly informative, phase-known meioses approximates 0.16 (75). Therefore, 20 such meioses are theoretically sufficient to establish linkage with a lodscore of 3. In practice, however, the number of individuals to analyze will be higher, a function among other factors of the quality of the marker, expressed as its Polymorphism Information Content (76) . The efficiency of this approach has been illus¬ trated by the recent mapping of a large number of genes involved in human single gene disorders (see, for instance, 77, 135). The identification of DNA markers for a defined gene can be the first step towards its molecular cloning. Successful "positional cloning", or the isolation of a gene based on its map location, has been achieved in the human for Chronic Granulomatous Disease, Duchennes Muscular Dystrophy, Retinoblastoma, Wilms Tumor, Cystic Fibrosis (134), Type-1 Neurofibroma- tosis and the Testis Determining Factor.

In domestic animals, genetic maps could be used to localize the genes underlying production traits, allowing for Marker Assisted Selection, and a first step towards their isolation, the understanding of their mechanism of action and their manipulation by mutagene- sis and gene transfer methods. Several laboratories around the world are now involved in the development of markers and the construction of genetic maps for our main domestic species, especially cattle, pigs and poultry.

III. GENETIC MAPPING OF QUANTITATIVE TRAIT LOCI

The majority of traits dealt with in animal pro¬ duction are so-called quantitative traits, characterized by continuous variation. The phenotype of an animal with respect to a particular trait is the result of the effect of a several "polygenes" known as Quantitative Trait Loci, or QTL, combined with environmental effects. The number of polygenes involved is essentially unknown. Classically, it is considered very large, each gene contributing a very small part of the genetic variation. However, there is evidence both from the plant world and the animal world, that QTL with significant effects are common (78, 79). The most likely model is to assume that there is indeed a large number of genes involved, but that there is a broad distribution of effects, substan¬ tial in some cases. Polygenes with extreme effects, whose segregation in a population may cause skewness and bi- or trimodality, are known as "major genes". Examples in animal breeding are "double muscling" genes in both cattle and pigs, the "White Shorthorn" gene involved in the determinism of "White Heifer Disease" and the "Booroola" fertility gene in sheep (80) . Even with significant effects on the trait of interest, however, their contribution to the total genetic variation may be limited in case of low population frequency.

When dealing with quantitative traits, direct determination of genotype for the corresponding QTL is impossible. Nevertheless, strategies have been designed to map QTL by linkage analysis. Within segregating populations, which is usually the case for our domestic species, QTL mapping can be performed both within families and at the population level.

A. QTL Mapping Within Families

Traditionally one proceeds as follows: offspring from an individual heterozygous for both marker and QTL are grouped according to which allele at the marker locus they inherited; a statistically significant difference between the phenotypic means of the two groups indicates linkage between marker and QTL. Test for statistical significance is done by linear regres¬ sion (i.e. one-way analysis of variance) under the assumption of normally-distributed residual environ¬ mental variance. Classically, markers are tested one at a time for possible linkage with a QTL affecting the trait of interest. One of the drawbacks of this approach is that it is impossible to unequivocally estimate both map location of the QTL with respect of the marker, and its effect on the considered trait; no distinction can be made between a closely linked QTL with small effect and a loosely linked QTL with major effect.

Recently, the lodscore method has been improved, making it possible to deal with quantitative and other complex traits and fully exploiting the power of the nearly complete marker maps which have become available for different organisms. This approach is known as interval mapping. Not only does interval mapping solve the problem of simultaneous estimation of location and effect, but because of its increased power, it reduces the number of individuals to be tested to detect linkage with a QTL of given effect (81) .

Assuming that the marker is the QTL, the number of individuals to test in order to detect an effect of given amplitude, δ , can be estimated from: 4 (t₀+t₁) ². s² n >

where n gives the required sample size, s² is an estimate of the residual variance, t₀ is the t value associated with Type I error, and t**_. is the t value associated with Type II error; t**_. equals tabulated t for probability 2(1- P) where P is the required probability of detecting «5 if such a difference exists (82) . For dairy production for instance, and if perform¬ ing the linkage analysis using the "daughter yield deviations" (DYD; σ² _DYDw 600 lb) from paternal half-sibs ("granddaughter design" (83) , one would have to study 1,500, 378 and 168 individuals, respectively, to detect QTL with differences of 200 lb, 400 lb and 600 lb between alternate alleles. Assuming phenotypic variance of (2500 lb)², such effects correspond to 0.08, 0.16 and 0.24 standard deviations, respectively. These estimates assume a Type I error of 5%, a Type II error of 10%, and absence of recombination between marker and QTL.

If the tested marker and the QTL recombine at a rate θ, the number of individuals to test increases by a factor 1/(1-2Θ)² for single marker analysis, by a factor «(l-τ)/(l-2θ)² in the case of interval mapping, r corresponding to the recombination rate between the flanking markers (81) .

In view of the costs and time involved in geno- typing, it is important to minimize the required sample size. This can be achieved in various ways:

a. Identification of the Individuals Most Likely to be Heterozygous, hence Informative, for the Studied OTLs

One way to achieve this is to cross highly diver¬ gent strains for the trait of interest. In plant breeding, where the use of exotic germplasm is common practice, this is perfectly applicable. The identification of markers for interesting QTLs from the exotic strains can then be used for their marker assisted introgression in the commercial varieties.

In animal breeding, however, introgression programs are very uncommon. With "Velogenetics" (described further below) , however, the use of exotic germplasm in introgression programs may become more attractive for animal breeders as well.

An alternative approach is to identify the indi- viduals whose offspring are showing a higher variance for the trait of interest.

b. Selective Genotyping of the Extreme Progeny

As pointed out by Lander and Botstein (75) , the individuals whose genotype can be most clearly inferred from their phenotype are the ones providing most of the linkage information when studying complex traits. For quantitative traits, these are the individuals whose phenotypic value deviates most from the mean: the tails of the distribution. Sample sizes could be reduced by 60% and even 80% by focusing on individuals deviating one and two standard deviations, respectively, from the mean. Paradoxically, selective genotyping may be limited by the size of the studied population. Indeed, a larger sample will be required in order to find enough individ- uals one or two standard deviations from the mean.

c. Decreasing Environmental Variance via Progeny Testing

Weller et al. (83) , have tested the effect of progeny testing to reduce the environmental variance by comparing the power of "daughter" and "granddaughter" designs for the detection of QTLs in dairy cattle. In the "daughter" design, marker genotype and quantitative trait values are assessed on daughters of heterozygous sires, while in the "granddaughter" design, marker genotypes are determined on sons of heterozygous sires, their breeding values being determined by progeny testing from the quantitative trait value measured on their daughters. They demonstrate that for equal power the "granddaughter" design requires half as many marker assays as the "daughter" design.

d. Reducing genetic noise by searching for several unlinked QTL simultaneously, or "simultaneous" search (81).

e. Using DNA Pools Instead of genotyping all individuals separately, one can analyze DNA pools from individuals sorted by phenotype. Significant differences of allelic fre¬ quencies between pools point towards possible genetic linkage between the corresponding marker locus and a gene or genes affecting the trait of interest. This approach can be used both for "within family" studies and for studies at the population level. The latter approach, however, requires linkage disequilibrium between QTL and marker locus. This method was first described by Arnheim et al. (84) to study the role of HLA class II loci in insulin-dependent diabetes mellitus. It was recently adopted by Plotsky et al. (85) to study association between DNA fingerprint bands and abdominal fat deposition in broilers.

f. Exploiting "Tagged QTLs"

The direct effect of selection for a production trait will be to increase the frequency of the favorable alleles at the segregating QTLs. However, this selection pressure may indirectly affect loci in linkage disequi- librium by so-called "hitch-hiking".

This is probably what happened to the genetic defect causing progressive degenerative myeloencephalo- pathy, or Weaver in Brown Swiss, shown to be linked to a major gene for milk production. Because of the deleterious effect of the Weaver causing gene, it is the heterozygous "carrier" genotype which is selectively most advantageous, generating a "balanced polymorphism", the Weaver causing allele being maintained in the population at a relatively high frequency. This can be exploited, however, to map the corresponding QTL by going through the relatively easy exercise (compared to QTL mapping) of finding a marker linked to this single gene disorder. We have recently identified a marker linked to Weaver and presumably to the associated QTL. Besides Weaver, QTLs for a variety of polygenic traits have been identified, both in plants and animals. Using complete DSP maps in tomato, Paterson et al. (78) identified at least six genes controlling fruit mass, four controlling soluble solids, and five controlling fruit pH, accounting for 58%, 44% and 48%, respectively, of the phenotypic variance. Martin et al. (79), using a similar approach, identified at least three tomato genes controlling water use efficiency. In cattle, Geldermann et al. (86) found significant effects on milk yield (+ 200 kgs) and fat content (+ 1%) , especially for the β-lactoglobulin locus. More recently, Cowan et al. (87) demonstrated significant effects on milk production traits using a prolactin DNA Sequence Polymorphism as marker.

B. QTL Mapping Within Populations

One can expect to find an effect of marker alleles linked to QTLs also outside of a family context, i.e., at the population level, if the two loci are in linkage disequilibrium. As reported by Hanset (88) , and assuming a diallelic marker (alleles Ml and M2 with respective frequencies pi and p2) linked to a diallelic QTL, the phenotypic difference between the respective homozygotes at the marker loci is:

D δ = 2a . pl.p2

with D measuring the linkage disequilibrium and 2a cor¬ responding to the phenotypic difference between the two homozygotes for the QTL.

Markers for which a priori evidence for linkage disequilibrium is highest are the so-called "candidate genes": genes expected from their physiological role to be likely candidates for the QTL itself. DSPs at those loci, even selectively neutral by themself, can be expected to exhibit linkage disequilibrium with the hypothetical functional mutations because of their very tight linkage. As an example, the B allele of the K- casein gene has been shown in several studies to increase protein yield in milk by about 3%, and possibly to improve cheese yield independent of the effect on protein yield (see, for instance, 89, 90) .

IV. USE OF DNA MARKERS IN BREEDING PROGRAMS

In classical selection programs, breeding values are estimated from individuals' own performances and performances of relatives (136) . The expected genetic progress is a function of the accuracy of selection, i.e. the correlation between estimated and true breeding values. All direct information on QTL can be used to increase the accuracy of selection and, hence, genetic response. Early on, Soller and Beckmann (91) proposed to exploit marker information for the preselection of young dairy sires before progeny-test. In cattle. Marker Assisted Selection is already used for the sexing of preimplantation embryos using Y-specific probes (see, for instance, 92), and for genotyping at the K-casein (see, for instance, 93) and prolactin loci (87) . In pigs, Marker Assisted Selection is used to reduce the frequency of the major gene causing Porcine Stress Syndrome (PSS) . Susceptibility to PSS correlates with Halothane sensitivity or Malignant Hyperthermia. This condition has been mapped to a linkage group on pig chromosome 6, encompassing the following markers: S(A- O)-GPI-Hal-H-AlBG-PGD (reviewed by 94). These markers are used for the Marker Assisted Selection against the PSS condition. Recently, the ryanodine receptor gene has been identified as a good candidate for the Malig¬ nant Hyperthermia or Hal gene (95) .

As shown by Smith and Simpson (96) , the gain to be made with Marker Assisted Selection increases with the proportion of QTL identified and is highest for low heritability traits. Unfortunately, the QTL determining the latter traits are also the hardest ones to identify. It should be noted that the increase in accuracy is subordinate to the accurate estimation of the QTL effects. This may require larger samples than the ones needed for the detection of linkage. Once a QTL mapped by within-family linkage studies, it may be more effec¬ tive to identify supplementary flanking markers and to accurately determine the effect of the generated haplo- types at the population level. Selection can then focus on the best haplotype instead of spending initial selec¬ tion efforts on intermediate ones.

The use of genetic markers in selection programs may as well reveal dominance deviation (particularly overdominance) and interaction deviation at defined QTL, variance components poorly dealt with in classical breeding theory. Specific programs may be required to fully exploit these QTL. In the case of overdominance for instance, two lines each homozygous for the differ¬ ent alleles at each QTL could be developed and crossed to produce multiple heterozygotes.

There is widespread interest in resolving quantitative traits into their Mendelian components by mapping the underlying QTL. The implementation of marker assisted selection into breeding schemes, however, has not always been received with enthusiasm. Part of the skepticism expresses the doubt that the genetic gains obtainable by marker assisted selection will justify expensive and tedious large scale genotyping. Although the costs of genotyping will drop substantially in the near future, due to the rapid pace at which automation and robotics are being applied to DNA technology, this objection remains very pertinent.

Another major limitation of marker assisted selection under its present form, is its limitation to the exploitation of genetic variation preexisting within the commercial breed of interest, and only that present in a "high merit" genetic background. Favorable mutations appearing within a mediocre background, or present in "exotic" germplasm, would be difficult to exploit, even with markers.

We have therefore proposed a scheme, designed as "Velogenetics", combining marker assisted introgression and germ-line manipulations to reduce the generation interval, which might drastically increase the power of marker assisted selection (141) .

IV. INDIVIDUAL IDENTIFICATION AND PATERNITY DIAGNOSIS:

Methods to estimate the breeding value of an animal use information from relatives. As a matter of fact, keeping track of familial relationships has always been one of the major concerns of animal breeders, and parentage control is now a widely used procedure for several domestic species. Parentage control relies on the use of polymorphic systems within the studied population. The alleles that characterize an individual originate from the mother or the father. If one of the parents is known (usually the mother) , the alleles necessarily transmitted by the other parent can be deduced easily. Paternity testing consists of scoring the existence or lack of those obligate paternal alleles in the genotype of the putative parent. Lack of one or more of these alleles points towards incorrectly assigned paternity. If, on the contrary, all obligate paternal alleles are present in the tested parent, there is no evidence for incorrectly assigned paternity. Nevertheless, one always has to consider the possibility of fortuitous coincidence. The higher the variation of the genetic markers used, the higher the probability to detect incorrectly assigned paternity, thus the higher the "exclusion power".

Until now, the systems most often used for paternity testing were blood group systems, biochemical polymorphisms, or the major histocompatibility system. The availability of DSP, however, opens new perspectives for paternity diagnosis. Hypervariable minisatellites in particular, characterized by their remarkably high degree of polymorphism, have proven especially useful in this respect. Multilocus DNA fingerprints, based on the simultaneous detection of related minisatellite loci, have been shown to be extremely powerful for paternity diagnosis, both in human (19) and animals (108, 109). Exclusion powers as high as 99.999996% have been obtained with as few as 2 probes in the human (19) . With such high exclusion powers, absence of exclusion can be considered proof for true biological parentage. Another corollary is that very high exclusion powers can be obtained even when a single parent is available and tested for parenthood. Multilocus DNA fingerprints, however, tend to be replaced by the combined use of a limited number of locus-specific VNTR markers (20) , giving equally powerful, but more reproducible, sensitive and easily interpretable patterns. With the advent of locus-specific VNTRs and PCR-amplifiable microsatellites in animal species (44) , the same will probably hold in this field too. Along the same lines, DNA markers can be used as well for individual identification. Using expansion- contraction type polymorphisms, individual specific "DNA bar codes" can literally be generated (19, 110).

SUMMJ-jRY OF THE INVENTION

Disclosed herein is a set of locus-specific genetic markers for domestic cattle and related bovids, that constitute a primary bovine DNA marker map. Among other applications, these markers and the map are useful for:

- individual identification,

- parentage testing,

- the genetic mapping of economic trait loci, or genes involved in the determinism of economicalli important traits, whether single gene traits or complex multifactorial traits,

- marker assisted selection,

- velogenetics, or the synergistic use of marker assisted introgression and germ-line manipulations to reduce the generation interval.

The usefulness of this set of markers for the genetic mapping of economic trait loci is illustrated by the identification of a genetic marker for bovine progressive degenerative myelo-encephalopathy or "Weaver" in the Brown Swiss breed.

BRIEF DESCRIPTION OF THE FIGURES

Figure 1: shows a typical VNTR pattern obtained with probe GMBT-005, using Haelll.

Figure 2: Example of a microsatellite pattern (TGLA9) . Figure 3: Schematic representation of

"Velogenetics". DETAILED DESCRIPTION OF THE INVENTION

I. CONSTRUCTION OF A PRIMARY BOVINE DNA MARKER MAP:

Our laboratory has focused in the last two years in the development of a primary DNA marker map for cattle. We have now developed more than 300 highly polymorphic DNA markers of either of three types:

1. Variable Number of Tandem Repeat Markers (VNTR) Hypervariable minisatellites are known to show significant cross-hybridization between species (31, 44, 110) . We have exploited this to isolate bovine VNTRs using heterologous minisatellite probes. Screening purpose-built libraries with minisatellite probes, we have isolated 36 bovine VNTRs, characterized by a mean heterozygosity of 59.3% within the American Holstein breed. Matching probabilities and exclusion powers were estimated by Monte-Carlo simulation, showing that the top 5 to 10 probes could be used as a very efficient DNA-based system for individual identification and paternity diagnosis. The isolated VNTR systems should contribute significantly to the establishment of a bovine primary DNA marker map. Linkage analysis, use of somatic cell hybrids and in situ hybridization demonstrate that these bovine VNTRs are organized as clusters, scattered throughout the bovine genome, without evidence for proterminal confinement as in the human (35) . Moreover, Southern blot analysis and in situ hybridization demonstrate conservation of sequence and map location respectively of minisatellites within Bovidae. A typical VNTR pattern obtained with one of our probes is shown in Figure 1. Detailed description of our VNTR systems is reported in "Example 1". 2. Multisite haplotypes

We used 110 random cos ids to probe Southern blots of 9 unrelated cattle DNAs digested with 12 restriction enzymes. Although only one third of the expected fragments could be detected, 85% of the cosmids revealed at least one polymorphism. The mean heterozygosity of the generated multisite haplotypes (98) was estimated at 51.9% . A surprisingly high proportion of polymorphisms («25%) was attributed to insertion-deletion events, compensating for the lower level of nucleotide diversity, π, observed in cattle (π « 0.0007) as compared to the human. The mutation rate at cytosines in the CpG dinucleotide was estimated approximately 10 times higher compared to other nucleotides. The generated markers should cover approximately 40% of the bovine genome when used in linkage studies. A detailed description of our multisite haplotypes is reported in "Example 2".

3. Microsatellites Recently, microsatellites were proven to be an abundant source of highly polymorphic markers in the human (32-34) . As their name implies, microsatellites are minute VNTR markers (18-20) , characterized by tandem repetitions of very short repeats, one to four base pairs in length. Microsatellites exhibit levels of polymorphism comparable to VNTRs, but are much more abundant and apparently evenly spread throughout the genome. We have estimated the frequency of (CA)- dinucleotide repeats in the bovine genome at > 150,000. Because of their small size, their detection is greatly facilitated by PCR. Although this imposes the preliminary determination of flanking DNA sequences to design the appropriate primers, the subsequent PCR reaction used for their analysis offers several advantages over Southern blotting, being fast, requiring less DNA and being easier to automate. As part of our effort to build a primary DNA marker map for cattle, we have isolated more than 250 bovine microsatellites, amplified most of them in vitro and shown that the majority of them are indeed polymorphic in cattle. Several of these have been tentatively assigned to specific bovine chromosomes using a somatic cell hybrid panel. Moreover, we have shown that approximately 50% of the bovine microsatellites can be successfully used in other Bovidae as well, which will greatly facilitate the construction of marker maps in these species.

Magnetic solid phase DNA sequencing procedures

(137) are used for the massive generation of sequence information and multiplex approaches for genotype collection, based on the simultaneous detection of molecules labelled with different fluorescent dyes using a laser-excited confocal fluorescence gel scanner (139) .

A typical microsatellite pattern is shown in Figure

2. A detailed escription of our microsatellites is reported in "Example 3".

The relative location of the markers was determined by linkage analysis in pedigrees generated by multiple ovulation and embryo transfer. To assign linkage groups to specific chromosomes, highly polymorphic "anchor markers" were mapped using somatic cell hybrids (Jim Womack, Texas A&M) , and by in situ hybridization (Rudy Fries, ETH - Zurich) .

Linkage analysis involving 150 of these markers, generated a primary DNA marker map with 24 linkage groups counting two or more markers (15 assigned to specific chromosomes or synteny groups) , and 68 singleton markers. A detailed description of our pri¬ mary bovine DNA marker map is reported in "Example 4". -Si¬

ll. MICROSATELLITE MAPPING OF A MAJOR GENE FOR MILK PRODUCTION, LINKED TO BOVINE PROGRESSIVE DEGENERATIVE MYELOENCEPHALOPATHY OR WEAVER.

Identifying polygenes, requires the analysis of pedigrees of considerable size, despite the development of procedures such as interval mapping, simultaneous search, selective genotyping, etc. In this work we have explored an alternative approach to map a polygene, exploiting the association observed in cattle between the single gene disorder "Weaver", and increased milk production. Weaver or bovine progressive degenerative myeloencephalopathy is a recessive disorder characterized by the appearance between 5 and 8 months of age of bilateral hind leg weakness, ataxia with deficient proprioceptive reflexes, without skeletal or muscular defects. Estimates of gene frequency in the American Brown Swiss breed point towards the maintenance of the Weaver gene at relatively high frequency (>5%) , despite the implementation of programs for detection and elimination of carrier bulls. Moreover, Hoeschele and Meinert (140) showed that Weaver carrier animals have an advantage of 690.8 kgs milk (> 0.25 phenotypic σ) above the mean. Both observations could be accounted for by the presence of a gene with major effect on milk yield in linkage disequilibrium with the "weaver" gene.

Brown Swiss animals showing symptoms of Weaver were identified with the help of the .American Brown Swiss Association. Blood samples were collected from the affected animals, their parents, and full-siblings when available. Diagnosis of Weaver was confirmed in most cases by anatomopathological examination of spinal cord and cerebellum at the Department of Pathology of the College of Veterinary Medicine, Kansas State University. Shrunken Purkinje cells in the cerebellum, spheroids and degenerated myelin sheets in the spinal cord were considered pathognomonic. Altogether, 78 animals were identified generating a single, large pedigree. All animals were genotyped for more than 70 genetic markers: 40 Variable Number of Tandem Repeat markers and more than 30 Microsatellites. Linkage analysis was performed using the "LINKAGE" programs (60) . The microsatellite marker TGLA116 was giving a highly significant lodscore of 6.5 for a recombination rate of 7.5%. Although a priori probability for pair-wise linkage is unknown in cattle, a lodscore of 3 is generally considered to be the threshold for statistical significance as in the human. This value (5.8) was obtained assuming complete penetrance. Actual penetrance for the Weaver condition is unknown. However, and because our pedigree was constructed by sampling clearly affected animals, the assumption of complete penetrance is very reasonable in this situation.

The marker TGLA116 is characterized by three alleles segregating in our Weaver pedigree. 72% of the affected individuals were of the 3/3 genotype, 16% of the 2/3 genotype, and 12% of the 1/3 genotype. Hence, and at least in our family material, the "Weaver" allele was clearly associated with allele 3 at the marker locus. Whether similar disequilibrium will be observed at the population level remains to be determined. The reported lodscore values were obtained using allelic frequencies estimated on a sampl of 135 sires from the American Brown Swiss breed.

Because of the biased sampling procedure used to generate the pedigree markers showing distorted segrega- tion could generate erroneous evidence for linkage with the disease. A "control" pedigree, consisting of more than 100 Weaver-free Holstein individuals, was therefore typed for TGLA116 as well. The microsatellite marker was characterized in this pedigree by the same three alleles, with respective frequencies of 18%, 57% and 25% for alleles 1, 2 and 3, showing a perfect Mendelian segregation. Therefore, it is concluded that marker TGLA116 is genetically linked to Weaver. From the generated lodscore curves, the genetic distance between the two loci is estimated at 3 ± 10 centiMorgan. The limits of this 95% confidence interval correspond to recombination rates with lodscores one unit below the obtained maximum lodscore. Because of the tight linkage between TGLA116 and Weaver, this marker should be linked to the associated QTL as well. The distance between TGLA116/Weaver and QTL is, however, unknown at this point. The effect using Weaver as marker, however, was of such magnitude that the genetic distance separating these loci is unlikely to be great. We are in the process of determining the relative location of these three loci. In consequence, the TGLA116 marker will allow us to perform marker assisted selection against the Weaver condition. Indeed, it is now possible for offspring from individuals heterozygous for both the Weaver condition and TGLA116, to estimate the genotypic likelihoods at the Weaver locus based on their TGLA116 genotype and that of their parents.

In addition, we are now in a position to test the effect of the corresponding chromosomal segment on milk production.

III. VELOGENETICS

Few question the fundamental interest of resolving quantitative traits into their Mendelian components by mapping the underlying QTL. The implementation of Marker Assisted Selection into breeding schemes, however, has not always been received with a lot of enthusiasm. Part of this skepticism reflects the disbelieve that DNA Marker Maps will become available for our domestic species within a reasonable time-span, or that QTL can be identified by linkage strategies. In our view, these arguments only reflect the lack of information of their protractors. On the other hand, part of the skepticism expresses the doubt that the genetic gains obtainable by Marker Assisted Selection will justify expensive and tedious large scale genotyping. Although the costs of genotyping will drop substantially in the near future, due to the amazing pace at which automation and robotics are applied to DNA technology, this objection remains quite pertinent.

Another major limitation of Marker Assisted Selec- tion under its present form, is its limitation to the exploitation of genetic variation preexisting within the commercial breed of interest, and only if present in a "high merit" genetic background. Favorable mutations appearing within a mediocre background, or present in "exotic" germplasm, would be difficult to exploit, even with markers.

We propose a scheme, combining Marker Assisted Introgression and germ-line manipulations, to reduce the generation interval — which might drastically increase the power of Marker Assisted Selection: "Velogenetics".

A. Marker Assisted Introgression

The basic principle underlying Marker Assisted Introgression are well-known. A gene responsible for a favorable attribute can be introgressed from a "donor" strain into a "recipient" strain by repeated backcross- ing. During the introgression process, the retention of the favorable gene is monitored in the backcross pro¬ ducts, with linked, flanking DNA markers. This latter aspect is particularly important for traits involving multiple genes and/or characterized by sex- or age- limited expression. Classical genetic theory tells us that, with the exception of the "marked" segment whose retention is desired, the genomic contribution of the donor line is diluted by half after each backcross. Hence, and after four backcrosses, the recipient genome is reconstituted to ± 90% of the original. At the marked locus, however, the backcross retains one copy of the desired "donor" variant. If required, one intercross will then generate 25% of offspring homozygous for the favorable donor variant. The net result is a "graft" of an advantageous gene within a recipient background. The procedures entirely respects organization and chromo¬ somal localization of the grafted gene, avoiding aberrant expression patterns, which are too often characterizing transgenes. Noteworthy, the gene to be transferred does not need to be cloned per se. Only its genetic map location is required, as defined by the availability of linked markers, ideally flanking the gene of interest on each side. Hence, this procedure is perfectly applicable for the introgression of QTL identified through the pre¬ viously described mapping strategies.

Marker Assisted Introgression can easily be applied to several genes simultaneously. This feature will be of particular interest for complex traits involving several genes. Introgressing more than one gene from a donor to a recipient line, however, increases the selection intensity at each backcross: with 1 marker, 1/2 of the offspring have the favorable genotype, with 2, 1/4 and with n markers, (l/2)ⁿ. Selecting for the retention of defined "donor" genes will hamper the recovery of the recipient back¬ ground genotype in adjacent chromosomal regions. This can be compensated for by increasing the number of backcrosses, or better by monitoring the fate of addi- tional adjacent markers to identify the backcross products resulting from recombinations as close to the "grafted" gene as possible.

B. Shortening the Generation Interval of Domestic Species by "Velogenesis" Introgression by repeated backcrossing, assisted or not by genetic markers, is common practice in a variety of organisms, but is essentially unfeasible in domestic animals such as cattle, because of their prohibitively long generation time. The generation interval of such species could, however, be reduced based on the "in vitro" maturation and fertilization of foetal oocytes, hereinafter referred to as "Velogenesis".

An overview of female gametogenesis (100,101), indicates that the feasibility of such a scheme may not be that far-fetched. Briefly, oogenesis begins with the formation of primordial germ cells in the region of the allantois. These precursor cells migrate to the developing gonads where after a period of mitotic proliferation, they enter meiosis. Meiosis is arrested at the diplotene stage of prophase I by the poorly understood "meiotic division I arrest system", after which the primary oocyte enters a resting phase. During the life time of the animal, small numbers of resting primary oocytes are successively recruited into a pool of growing oocytes, within the environment of a gonadotropin-dependent developing follicle. These activated oocytes growth in size, acquire the competence to resume meiosis if appropriately stimulated, and accumulate the required material to sustain the early stages of the subsequent embryonal development. Resumption of meiosis and oocyte maturation is triggered by a hypothetical maturation-inducing signal produced by granulosa cells in response to gonadotropins. At least in rodents, oocyte maturation seems to be mediated by a drop in cyclic AMP in the oocyte and subsequent inactivation of a type A protein kinase. Evidence for the role of this pathway in oocyte maturation is, however, much more controversial in ruminants. Note that in the granulosa cells, gonadotropins act, among other pathways, through the activation of adenylate cyclase with subsequent increase in cAMP concentrations (102) . In the oocyte, a cascade of still to be deter¬ mined events then probably leads to the phosphorylation and activation of a phosphatase, probably homologous to the S. Pombe cdc25 gene (103) , which will itself dephos- phorylate and activate the M-phase promoting factor (MPF) , now known to be a complex of a p34^cdc2protein kinase subunit with a B type cyclin (see 104 for a review) . The maturing oocyte completes the first meiotic division and enters the second (becoming a secondary oocyte) which will be arrested as well at metaphase II until fertilization. This "meiotic division II arrest system" is thought to reflect the stabilization of MPF mediated by the kinase activity of pp39^os on either a cyclin protease or on cyclin itself. Fertilization relieves this block, by increasing the intracellular Ca²⁺ concentration, triggering calcium- dependent protease activity (reviewed in 104) .

In cattle, primordial germ cells reach the genital ridge at about 40 days of gestation. After a period of mitotic proliferation, they differentiate into oogonia starting around 60 days of gestation. Mitotic prolifera- tion of the germ line ceases around day 170 of gestation fixing the maximum number of oocytes the female will ever have. Meiosis starts at about 80 days, and the first primordial follicles are discernable at 90 days of gestation. Remarkably, activation of resting primordial follicles starts already in utero. around day 140, and secondary and tertiary follicles can be seen at 210 and 230 days, respectively. It is estimated that 2 to 4 resting primordial follicles are recruited daily into the pool of activated, developing follicles. These activated foetal oocytes, however, are irrevocably committed to follicular atresia. Indeed, spontaneous oocyte maturation and ovulation do not begin until puberty. Submitted to appropriate hormonal stimulus, however, prepubertal oocytes can resume meiosis, can be fertilized and can produce viable offspring. Indeed, offspring have been obtained from gonadotropin- stimulated calf oocytes, transferred to postpubertal recipient animals (reviewed in 105) . The purpose of velogenesis would be to attempt to obtain similar results with foetal oocytes at the earliest stage possible, as early as 90 to 180 days of gestation. Very encouraging is the development in mice of culture systems supporting the growth of primary follicles, yielding mature oocytes capable of fertil¬ ization in vitro and development to term (106, 107) . It is reasonable to anticipate that similar conditions, supporting development of bovine oocytes, will become available in a species were primary oocytes from relatively small antral follicles can already be successfully matured and fertilized in vitro.

On way to achieve velogenesis would be to attempt to rescue oocyte nuclei from primordial follicles by their transfer into enucleated, maturable oocytes.

So far we have only discussed velogenesis through the reduction of the female generation interval. "Male" velogenesis could similarly be accomplished by the early stimulation of spermatogenesis.

The impact on breeding programs of "velogenesis" or the reduction of generation time by in vitro maturation and fertilization of fetal oocytes has been discussed by Betteridge et al. (101) . In dairy breeding, for instance, annual responses in milk yield could be doubled compared to conventional progeny testing. With the added power of Marker Assisted Introgression, the approach becomes much more powerful. "Velogenetics", or the synergistic use of Marker Assisted Introgression and "velogenesis", can be viewed as a procedure for the rapid and efficient intraspecies transfer of desirable genes between genetic backgrounds. By analogy with the term "transgene", the manipulated genes are referred to as "velogenes". In particular, desirable traits identified outside commercial breeding stock, could be quickly introgressed into high merit genetic backgrounds. Examples would include disease resistance, genes affecting milk and meat composition, Polled, coat color genes, etc. More¬ over, the possibility to exploit "exotic" genetic variation identified outside the breed of interest is particularly attractive because it greatly facilitates the mapping of the genes of interest.

A schematic representation of "Velogenetics" is shown in Figure 3.

The present invention is further detailed in the following Examples, which are offered by way of illus¬ tration and are not intended to limit the invention in any manner. Standard techniques well known in the art or the techniques specifically described below were utilized.

EXAMPLE 1

CHARACTERIZATION OF

A SET OF VARIABLE NUMBER OF TANDEM REPEAT MARKERS

CONSERVED IN BOVIDAE.

INTRODUCTION

Human minisatellite sequences, exhibiting very high levels of genetic polymorphism due to variation in the number of tandem repetitions, have proven an invaluable source of genetic markers commonly termed "VNTRs" (18- 20) . VNTRs have been instrumental in the genetic mapping of several disease-causing genes, as tools for individual identification and paternity diagnosis and to address a variety of biological issues, including imprinting, loss of heterozygosity in malignancies, etc.

In animal genetics, highly polymorphic markers such as VNTRs could similarly be used for individual identification and paternity diagnosis - relying today on less informative biochemical polymorphisms and blood group systems -, and for the mapping of so-called economic trait loci (ETL) or genes involved in the determination of production traits. Classically, artificial selection has relied on the biometrical evaluation of breeding values from individual performance records and from performances of relatives (136) . One of the powers of the biometrical approach is that it obviates the need for any detailed molecular knowledge of the underlying genes or ETL. However, it is believed that the genetic mapping of ETL could be used to increase genetic response by affecting accuracy and speed of selection, through a procedure called marker assisted selection (MAS) (91, 96) . Moreover, defined alleles could be moved efficiently between genetic backgrounds by velogenetics or the combined use of marker assisted introgression and germline manipulations aimed to reduce the generation interval (141, 142).

We report the cloning and characterization of 36 bovine variable number of tandem repeat (VNTR) markers, characterized by a high degree of polymorphism within commercial herds and shown to be conserved within

Bovida .

MATERIALS .AND METHODS

l. Cloning of bovine VNTRs and detection of polymorphism:

500μg genomic DNA from 20 unrelated cows was digested to completion with Mbol or Haelll. After two rounds of size fractionation by agarose gel electrophoresis, electroelution and addition of EcoRI linkers (only for Haelll restricted DNA) , fractions from 3 to 4 Kb (kilobases) , from 4 to 6 Kb and above 6 Kb were ligated into the BAP-dephosphorylated BamHI and EcoRI sites, respectively of pUC13. Approximately 80,000 independent clones were obtained by transformation of DH5α cells, and were screened successively with the following minisatellite sequences: the 282 base pair Haelll-Clal fragment containing the minisatellite in the protein III gene of wild-type M13, pUCJ, pSP64.2.5EI ('Per'), pα3'HVR64, pINS310, EFD134.7 and pS3 (20, 21, 110, 123, 143). Hybridization and washings were done in the conditions used to generate multilocus DNA fingerprints with the respective probes (110, 143) . To check for polymorphism, plasmid DNA isolated from positive colonies was used to probe Mbol, Haelll and TaqI Southern blots of 18 randomly selected American Holsteins. Hybridizations were done at 65 C in 7% SDS, 10% PEG, 50mM NaHP04 with addition of 50μg/ml bovine genomic DNA. Final washes were at 65 C in O.lxSSC, 0.1% SDS. When using bovine probes on ovine Southern blots, hybridization and washing temperatures were reduced by 10 C.

2. Estimation of Matching Probabilities and Exclusion Powers: Allelic frequencies were estimated from the sample of 18 randomly selected American Holsteins. Matching probabilities and exclusion powers (113) were then estimated by Monte-Carlo simulation (10,000 simulations in each case) , assuming Hardy-Weinberg equilibrium and using "Pat-Power", a program designed by one of us. The following parameters were estimated: MPR: matching probability for two randomly selected individuals; MPS: matching probability for full-sibs; EPR: probability to exclude an alleged father unrelated to the real one (mothers phenotype known) ; EPS: probability to exclude an alleged father full-sib to the real one (mothers phenotype known) ; EP1: probability to exclude a wrongly assigned parent without phenotypic information available from the other one. Patpower calculates Matching Probabilities and Exclusion Powers characterizing given autosomal poly¬ morphic systems, by Monte-Carlo simulation.

Matching Probabilities relate to individual identi- fication and express the likelihood that two individuals would have the same pattern with a given probe. Patpower calculates two types of Matching Probabilities: MPR, the Matching Probability for two unrelated individuals, and MPS, the Matching Probability for two full-sibs. Exclusion Powers relate to paternity diagnosis and express the likelihood that a wrongly assigned paternity or maternity will be detected with a given probe. Patpower determines three types of Exclusion Power: EPR, where one parent is known with certainty, the proband is unrelated to the other real parent; EPS, where one parent is known with certainty, the proband is full-sib of the other real parent; and EPl, whre only the proband is available.

The user needs to input the number of alleles char- acterizing the polymorphic system in the population of interest, their respective frequencies, and their dominance-recessivity relationships. For the ABO blood group system in humans, for instance, A and B are codominant and both dominate 0. Each allele is given a binary code following the rules of the "LINKAGE" program (60).

Patpower then stochastically generates a pair of parents with an offspring, a full-sib of the real father and an unrelated individual. "Phenotypes" are obtained from the genotype using the boolean "or" operator and are used to determine matching between unrelated indivi¬ duals (MPR) and between full-sibs (MPS) , as well as the exclusion of the unrelated individual considered as a proband, with (EPR) and without information (EPl) from one of the real parents, and exclusion of the uncle considering information from the real mother (EPS) . This simulation is repeated as many times as determined by the user, allowing for the estimation of the respec¬ tive livelihoods.

3. Segregation and linkage analysis:

All members of an .American Holstein pedigree with 91 offspring obtained by multiple ovulation and embryo transfer (MOET) from 20 parents, were genotyped for all identified markers. Each parent has a mean of 9.1 offspring with a mean of 1.9 partners. Segregation and linkage analysis were done with slightly modified versions of the "LINKAGE" programs as previously described (31) .

4. Synteny mapping:

The hybrid somatic cells were prepared by fusion as previously described (97) . Southern blot hybridization and concordancy analysis were done according to Threadgill et al. (114).

5. in situ hybridization:

Chromosomes were prepared as described by Fries et al. (115) and chromosome identification was based on QFQ-banding and according to the international standard

(116) . Probe preparation and in situ hybridization were as previously described (144) .

RESULTS 1. A set of bovine VNTR markers: Using the strategy described above, we have isolated a total of 36 bovine VNTRs, listed in Table 1. Polymorphic patterns were attributed to minisatellite sequences when characterized by more than two alleles distinguishable with more than one restriction enzyme. Seven additional, non VNTR-type polymorphisms were detected during this experiment and are reported as well. Qvin⁵

LOCUS:locus name following HGM nomenclature rules whenever available from mapping studies.

POLYMORPH:type of polymorphism (VNTR:Variable Num¬ ber of Tandem Repeats; PM:Point Mutation; (?) :un¬ explained) .

3 ENZ:preferred restriction enzyme for its detection.

4 HET:heterozygosity within Holszteins, estimated from a sampel of 27 presumably unrelated Holstein animals.

OVIN:cross-reaction in sheep; N, negatie; M, mono- morphic; P, polymorphic, not tested. Within the .American Holstein breed, the mean heterozygosity over all VNTR systems was 59.3%. When using probe GMBT-016 with Mbol instead of Haelll, and supposedly because of the presence of minisatellite variant repeats (MVR) (39) harboring Mbol sites, an extremely variable, locus-specific "midisatellite" pattern (36) is generated (data not shown) . Used with Mbol, this probe is particularly powerful for individual identification. We found one clear instance of maternal neomutation with probe GMBT-022. Besides this, all probes showed proper Mendelian segregation.

Table 2 reports estimated matching probabilities and exclusion powers as well. Systems GMBT-009, GMBT- Oil and GMBT-022 were treated as "open" systems, meaning that - because of their small size - some alleles were not detectable in our conditions. To avoid ambiguities in identification and paternity diagnosis, these unidentified alleles were pooled in a single "recessive" class. For individuals showing a single band, no distinction was made between homozygosity and heterozygosity based on band intensity.

Discrepancies between probe ranking according to heterozygosity versus ranking according to matching probabilities and exclusion power, most probably results from the small sample size used to estimate both types of parameters. However, heterozygote advantage at some loci could be an alternative although unlikely explanation in view of the apparent neutral behaviour of human minisatellite sequences (124) . TABLE 2

T t ued

1 MPR is Matching Probability for two randomly selec¬ ted individuals.

2 MPS is Matching Probability for two full-sibs.

3 EPR is Exclusion Power when putative father is unrelated to real father. 4 EPS is Exclusion Power when putative father and real father are full-Sibs.

5 EPl (or EPSP) is Exclusion Power when only one parent is available.

2. Genomic distribution:

We performed pair-wise linkage analysis between all markers. As it is known that at least some of these sequences are organized as minisatellite clusters (31, 35, 145), we were expecting to find tightly linked systems. We found evidence for five pairs of linked markers of which four were characterized by a recombination rate inferior to 5% (Table 3) . However, two of the systems involved in a tight linkage detect non VNTR-type polymorphisms (GMBT-014, GMBT-022) . The corresponding probes were probably isolated because they contain a genuine although non-polymorphic minisatellite, and were fortuitously detecting other types of polymorphism. Despite these five linked pairs, results of the linkage analysis pointed towards a scattering of these markers throughout the bovine genome.

TABLE 3

Linked Systems θ¹ lodscore² GMBT-003 and GMBT-029 0.0% 5.00 GMBT-007 and GMBT-059 11.3% 9.11 GMBT-009 and GMBT-014 4.8% 3.74 GMBT-015 and GMBT-016 3.7% 27.00 GMBT-028 and GMBT-047 2.5% 9.40

1 θ = recombination rate.

2 pair-wise lodscores were calculated with the "LINKAGE" programs.

Reference markers for the respective synteny groups were U1:GNB1, U2:ME1, U3:NKNB, U4:MPI, U5:FOS, U6:AMY1, U7:LDHA, U8:GNB2, U9:GPI, U10:SOD1, U11:VIM, U12:GPX1, U13:MET, U14:GSR, U15:CASK, U16:ABL, U17:CRYG, U18:GGTB2, U19:CAT, U20:GL01, U21:GH, U22:.AMH, U23:ALDH2, U24:TG, U25:CLTLA, U26:OAT, U27:DU27Slb, U28:MBP, U29:RBP3 and X:DMD. Synteny groups with highest concordancy scores, to which corresponding VNTRs were assigned, are underlined. Evidence for a broad genomic distribution of our

VNTRs was supported by the tentative assignment of 13 of them to 11 different synteny groups using somatic cell hybrids (Table 4) . GMBT036 identifies a previously unmarked bovine synteny group. Probe GMBT-021 was assigned to the same synteny group as probes GMBT-015 and -016. Although the latter two probes were shown to be tightly linked, linkage between those probes and the former one could be excluded for recombination rates < 15%.

TABLE 4

Concordanv Analysis for Synteny Mapping of VNTRs

TABLE 4 (Continued) Concordancv Analysis for Svntenv Mapping of VNTRs

t

Eight VNTRs were as well mapped by "in situ" hybridization: GMBT-006 to 14qll-16, GMBT-005 to 24ql3.3-22, GMBT-011 to 26qll-21, GMBT-015 and GMBT-016 to 21q22-24, GMBT-019 to 10ql4-23, GMBT-022 to 19q21-23, GMBT-028 to 2ql3-21. Again good genomic coverage was evident, since six probes mapped to five different chromosomes. Probes GMBT-015 and -016 both mapped to 21q 23-24 as expected from the linkage study and the assignment on the hybrid panel. Surprisingly, five out of the eight VNTRs clearly showed an interstitial map location. Only probes GMBT-015, -016 and -022 were located proterminally, the former two identifying the same minisatellite cluster. These results seem to contrast with those of Royle et al. (35), which demonstrated preferential proterminal mapping of human VNTRs. Probe GMBT011, previously located on U26, was mapped to chromosome 26, allowing us to tentatively assign synteny group U26 to chromosome 26.

3. Conservation of sequence and map location within Bovidae:

We hybridized ten bovine VNTRs to sheep Southern blots, under slightly reduced stringency conditions. Seven of them were yielding locus specific patterns, of which six were showing a substantial degree of poly- morphism in a sample of 5 unrelated sheep (Table 1) .

Probes GMBT-016, -019 and -022, mapping in the bovine to 21q23-qter, 10ql5-q24 and 19q21-qter respectively, were mapped by in situ in sheep as well. The three probes produced signals on chromosomes 18, 7 and 11, recognized as evolutionary homologues of bovine chromosomes 21, 10 and 19 (116) . Moreover, the signals were found over the exact positions as expected in case of conservation of chromosomal location in cattle and sheep. DISCUSSION

To isolate bovine VNTRs, we have used a strategy similar to Wong et al. (146, 147), based on the screening of size-selected restriction fragments obtained by complete digestion with the four-cutters Mbol and Haelll. Advantages of this strategy are: (1) the complexity of this size-range is substantially reduced; following Bishop et al. (128) and assuming an exponential distribution of restriction fragment lengths, the fragments > 2 Kb represent about 10^~3 of the total number of Mbol or Haelll fragments, corresponding to approximately 10^A fragments; this allows us to work readily with plas id vectors; (2) the subsequent search for and use of the polymorphism is performed with the same enzyme used to generate the libraries, obviating the need to screen several restriction enzymes, hence reducing costs; (3) relying on frequent four-cutters, the cloned minisatellites contain very little flanking sequences and only very few of them carry highly repeated sequences which would interfere during hybridization; (4) theoretically, the larger minisatellites targeted by this approach are more likely to be involved in mutational events and could therefore be the more polymorphic ones. A disadvantage of this approach is the unequal representation of minisatellite loci in our library. The libraries were generated with a mixture of DNA from 20 unrelated individuals, to increase the number of clonable microsatellites. As a consequence, loci for which most alleles are within the selected size range will be overrepresented, compared to loci for which the majority of alleles in the population are bellow this range.

This collection of bovine VNTRs could be used for DNA based individual identification and paternity diagnosis. Combining our top 5 probes, matching probabilities and exclusion powers at least as good as those obtained with classical systems are obtained: MPR: 8xl0^"8, MPS: 4xl0^"3, EPR: 0.999, EPS: 0.893, EPl: 0.987. Adding more probes will of course only increase the power of the system. As a matter of fact, these probes have been used efficiently to solve paternity problems beyond the power of blood group systems. DNA typing is not limited to blood samples as present systems are, which expands its spectrum of applications and power. As an example, DNA typing has been used to deal efficiently with fetal blood cell chimerism (127) , frequently encountered in cattle. Compared with multilocus DNA fingerprints, locus-specific VNTRs are much easier to interpret and are more reproducible. Following properly established standardization procedures, a "common language" could be established allowing exchange of information between laboratories. It is noteworthy that heterozygosity and allelic frequencies for some probes seem to vary substantially between breeds. As an example, probe GMBT-012 is characterized by an heterozygosity of 22% in Holsteins, but higher than 50% in both Herefords and Brown Swiss. Hence, proper use of these probes may initially require accurate estimation of genetic variation for different breeds.

Assuming a coverage of 20 cM per marker in linkage studies, the set of markers described in this paper would allow the scanning of approximately 7 Morgans. Accepting a total map length for the bovine genome of 25 Morgans (148), this represents close to 33%. We have complemented the set of bovine VNTR described in this paper with over 80 multisite haplotypes, generated with cosmid probes, and more than 100 microsatellite systems (31, 148, 149). Therefore, the majority of the bovine genome is now amenable to linkage scanning. Since several of these markers are already "anchored" to specific chromosomes or synteny groups, a primary bovine DNA marker map should soon be available. Moreover, the remarkable conservation of mini- and microsatellites within Bovidae will substantially accelerate the construction of genetic maps in sheep and goats and offer the possibility to address interesting evolutionary issues.

EXl-iMPLE 2

GENERATION OF BOVINE MULTISITE HAPLOTYPES USING RANDOM COSMID CLONES.

INTRODUCTION

The possibility to generate nearly unlimited numbers of genetic markers through the study of DNA Sequence Polymorphism (DSP) (76) , has revolutionized human genetics: genetic markers have been used to map genes involved in a variety of human diseases, which has direct implications for genetic counselling strategies and is a first step towards their subsequent cloning by reverse genetics; they are revolutionizing individual identification and the examination of familial relationships; and they are invaluable tools in the study of a wide variety of biological issues. In particular, they are expected to play a key role in the ongoing efforts to entirely map and sequence the human genome. For breeders of domestic animal species, the availability of large numbers of genetic markers means, besides new approaches for individual identification and paternity diagnosis, the possibility to map and study genes determining production traits , and to use this information in marker assisted selection and velogenetics (91, 96, 141, 150).

Particularly challenging is the fact that the majority of production traits are complex, ultifactorial traits. Animal breeders, however, have the advantage that phenotypic information has been carefully recorded for thousands of animals over the years for use in classical biometrical breeding programs, and that they can, if necessary, design and generate the ideal family material required for such mapping studies.

In both the human and animal field, polymorphic markers characterized by the highest possible hetero- zygosities or "Polymorphism Information Content" (PIC) (76) is paramount. Hence, the focus has changed from the original diallelic Restriction Fragment Length Polymorphisms (RFLPs) to more informative systems based on the study of sequences such as minisatellites (18, 20) , and more recently microsatellites (32-34) and the polydeoxyadenylate tract of SINE-repetitive elements (37) . Minisatellite sequences in particular have proven very powerful. They seem to suffer, however, from a non-random genomic distribution, especially in the human where in addition, they show proterminal confinement (35) . Microsatellites, although very abundant and highly polymorphic, require prior sequencing efforts to generate the primers needed for their in vitro amplification. Moreover, the large scale use of microsatellites requires the development of more efficient multiplex amplification and data collection schemes.

An alternative strategy for the generation of highly informative marker systems is to combine several, closely spaced diallelic RFLPs into more informative polyallelic multisite haplotypes (98) . We have explored the use of random bovine cosmid clones in Southern blot hybridizations in order to identify such sets of closely spaced DNA Sequence Polymorphisms. Because of the population structure imposed by breeding strategies, effective population sizes of domestic species are expected to be reduced compared to humans. It was interesting therefore, to check in how far this would decrease the observed level of genetic variation and in how far the expected concomitant increase in linkage disequilibrium would affect the efficiency of the chosen approach in domestic animal populations.

MATERIALS AND METHODS

1. Preparation of cosmid clones:

Bovine genomic DNA was prepared using standard procedures, partially digested with Mbol, and size fractionated by rate zonal centrifugation in a 10%-40% sucrose gradient. Size fractions around 40 Kb were ligated into the Xhol site of the cosmid vector pWEC (pWE 15 vector (Stratagene) with pUC18 polylinker - Erica Cumlin, personal communication) , after partial fill-in of the insert and vector sticky ends with respectively dATP, dGTP and dCTP, dTTP. The obtained constructs were packaged into Gigapack II Gold extracts (Stratagene) and used to infect E.Coli 490A hosts (gift from R. White, University of Utah, Salt Lake City, Utah, USA) . 110 colonies were selected at random, cosmid DNA was prepared using standard procedures, and purified by CsCl/Ethidium Bromide isopycnic centrifugation.

2. Southern blot hybridization:

Genomic DNA from 9 unrelated Holstein individuals was prepared from venous blood using standard procedures and digested with 5U/μg of the following enzymes in the presence of 4mM spermidine: BamHI, Bgll, Bglll, EcoRI, EcoRV, Hindlll, Kpnl, Mspl, PstI, PvuII, TaqI and Xbal. 4μg DNA per individual was separated according to size by agarose gel electrophoresis and blotted onto Pall Biodyne B membranes using NaOH 0.4M as transfer buffer. Membranes were prehybridized at 65 C for 4 hours in 10% PEG, 7%SDS, 50mM NaHP04 (pH 7.2) in the presence of 350μg/ml bovine genomic DNA. Cosmid DNA was labelled by random-priming (111) to specific activities of .5*10⁹ cpm/μg, prehybridized with bovine genomic DNA (5mg/ml) for 90 min. at 68 C (112) , and added to the prehybridized membranes for 16 hours. Final washes were in 0.1XSSC, 0.1%SDS and at 65 C. Autoradiography was carried out for 2 to 6 days at - 80 C with Kodak XAR-5 film and intensifying screens (DuPont Cronex Lightning- Plus) . Membranes were stripped by boiling into 0.1%SDS and reused up to at least 10 successive times.

3. Calculation of nucleotide diversities:

Nucleotide diversities, π, corresponding to the average heterozygosity per nucleotide site were estimated following Ewens et al. (130), using: TΓ =

2∑r_im_ilnn_i

where n_t stands for the number of chromosomes studied with the i^th enzyme, r_± for the number of bp of the recognition sequence of the i^th enzyme, mi for the number of cleavage sites explored with that enzyme, of which k_± are polymorphic.

The number of explored restriction sites was estimated from the number of fragments f observed by Southern blotting, using m = (3f+l)/2 (119) .

RESULTS

110 randomly selected bovine cosmid clones were used in Southern blot hybridization experiments as described in Materials and Methods. 96 of them, or 87.2%, gave usable patterns and were kept for further analysis. Combining data from the 12 restriction enzymes used, a mean of 53.87 fragments per cosmid qualified as unambiguously readable. The only RFLPs considered in this paper, are the ones affecting these selected fragments.

Assuming a cosmid insert size of 40 Kb and estimating the mean restriction fragment length in Kb (L) for a restriction enzyme according to Bishop et al. (128) , the expected number of restriction fragments detected in Southern blot hybridization per cosmid probe for a given enzyme can be approximated by: integer(40/L)+l. For our 12 enzymes, we expect therefore a total of 173 fragments per cosmid probe. Therefore, the 53.87 fragments actually observed per clone, represent only 31% or less than 1/3 of what is theoretically possible. The remaining 69% are missed either because they were considered difficult to read, or more often because they went undetected due to their abundance in highly repetitive elements blocked by the competitor DNA, or due to their size, too small for efficient detection in our conditions of Southern blot hybridization. The smallest fragments qualifying as readable in this study, were in the 1 Kb size-range. The latter factor is particularly apparent with the two used four-cutters, Mspl and TaqI, whose expected mean fragment length are the lowest (1747bp and 1179 bp respectively) despite the presence of the rare CpG dinucleotide. Only about 15% of the expected number of fragments are detected for these two enzymes.

Nevertheless, as much as 82 of these 96 cosmids, or 85%, were showing at least one polymorphism within our sample of 9 randomly selected individuals. The detected polymorphic events are classified into two groups: 1) Point Mutations ("PM") , whenever a defined polymorphic pattern is only seen with a single enzyme, and 2) Insertions-Deletions ("ID"), whenever such a pattern is seen with two or more enzymes. Following these rules, we identified 215 polymorphic events, or a mean of 2.6 independent RFLPs per cosmid probe. 162 of these (75.3%) were considered of the PM type, the remaining 53 (24.7%) of the ID type. Table 5 summarizes these results.

TABLE 5

Bovine Multisite Haplotypes

K3BT013 ΪIDΪ22)

9.5/10 2P!^≠.(6) ?/3.7

BSBT015 1IDC44. 2PH.23) 110(44) 14/13 25/22 8.5/6.5

HSBT016

HSBT017 TABLE 5 (Continued)

NAKE Hindlll Kpnl Hs l PstI PvuII

MSBT019 ??(??) 1PK122⁾ 20/17+2.B 2PH147J 30+5.5/36

HSBT020 lPH⁽ll⁾ 4.3/5.5

HSBT001210(55) 110(11) ??(??) 9/12.5 ?/8.B 210(55) 12/12.5

HSBT005 110(17) 110(17) 110(17) 5.B+5/5.4+4. 4PI.(50) 4/7.B

HSBT007110(17) 110(17) 12/6.B 8.2/9.5

HSBT009 1PK(44> 2PH(46) 3.9/5.7 4.5+5.1/9.5

HSBT00A 2PK(2B)

5/6.5

3PN⁽11⁾

3.8/2.8

4PHC5⁾

11/9.3+1.E

HSET0114PH122⁾ 16/14

MSBT013 110(22) ??!??) 19/16 TABLE 5 (Continued)

NAKE Hindlll Kpπl Mspi PstI PvuII

RSBT015 ??(??)

RSBT016 1ID(40) 5.8+4.3/6.5

HSBT017

HSET019 3P«(50) ?? (??) 11/6.4+4.3

HSBT0202PK(22) 15/10

TABLE 5 (Continued)

TABLE 5 (Continued)

NAME BaiHI Bgll Bglll EcoRI EcoRV

KSBT0221PK(47! 2PK(47) 3.3/3.5 5.B/2.5+3.2

3PH(5)

5.8/9.2

4PKC8Ϊ

?/2.1

KSBT023

KSBT0301P!U67! 8/5.8+2

KSBT031 ??(??)

KSBT0321PKC22! 9.6+6/16

HSBT033

MSBT034 TABLE 5 (Continued)

NAKE HindiII Kpπl Hspl PstI PvuII HSBT022

KSBT023 1PK.45) 5.5+3.7/3.2+2

KSBT024110(26) 110(26) 110(26) ?/7.B 7.5/5 13/14

KSBT025 ??(??!

HSBT026 ? 2??(??)

HSBT028

HSBT030 3??(??) 3.3/3.1

HSBT031 ??(??! ??(??) ??(??)

KSBT032210(11⁾ 210⁽11⁾ ?/12 ?/2.7 3PH(33! 4.6/4.9 410(56) 4/3.4

HSBT033210(44) 410(66) 4ID(66) ??(??! 14/15 6.5/2.5 1.7/4.3 ??(??)

HSBT034 110(44) ??(??) 1ID(44) 5.9/3.9 4.7/4.3 2PH(22) 5.3/4 TABLE 5 (Continued)

KSETC3: ??(??

^{TABLE 5} (Continued)

NAKE BaiKI Bgll BgllI EcoRI EcoRV HSBT035 110(55) 6.3/6.6

KSBT039 IPK(ll) 9/9.6

HSBT040 1PE.22! 18/16

HSBT041

TABLE 5 (Continued)

TABLE 5 Continued)

TABLE 5 (Continued)

NAKE BaiHI Bgll Bglll EcoRI EcoRV

KSBT048

KSBT049 110(22! 110(22) 9/3.9+5.3 9.7/4

KSBT050 1PK(??) ?/8.2

HSBT0512PHC22) lPK(ll) 20/18 7/14

HSBT052 110(11) 2ID(??) 17/14

KSBT053 1PK(??)

KSBT054

K3BT056 110(55)

HSBT057

KSBT059

HSBT060

HSBT061 - 73 -

TABLE 5 (Continued)

KSBT051 3PK (??1

HSBT052 1ID(??) 110(11) 12/10.5

KSBT053

KSBT054 1PK(22! 2.6/2.9

KSBT056 110⁽55) 3/2.7

HSBT057

KSBT059 110(33) 12/11

HSBT060 110(11) 4PH(??1 6.2/6.8 2.7/1.4

BSBT061 110(44⁾ 110(44) 7+2.4/9.3 4.7/5.2 _TABLE 5 (Continued)

HAKE TaqI Xbal HET.

HSBT049 22

TABLE 5 (Continued)

HSBT079 ??(??)

HSBT080 110(11! 4.5+2/5.7+4.3

HSBT0B1 ??(??) ??(??) ?/ll - 76-

TAB LE 5 ( Con inue )

MSBT074 1PK(22) 2PK(44) SPK⁽33^*, 4.E/5.3 10.8/12/9.5 3.3/5.7

3PKJ331

17/16.5

4PK(44)

10.8/12/9.5

HSBTOBi 2PHC33! 2.2/2.7 TABLE 5 (Continued)

KSBT074 66 KSBT074 0 KSBT074 0

MSBT060 2PKU1) 22 6.3/3.9+2.5

RSBT0B1 33 -78-

TABLE 5 Continued

KSET093

HSBT094

HSBT096

HSBT097

KSBT0B TABLE 5 (Continued)

NAME Hindlll Kpnl Kspl PstI PvuII

KSBT083 4PK(??) Ill

KSBT084 2P (22) 5.1/3.9

HSBT085 210(22) 12/5.7

MSBT086

KSBT093 1PK(33) 4.7/1.9+2.5 2PM (33) ?/3.3

BSBT094

MSBT096 lPK(ll) 8/4.8+3.2

MSBT097 1PK(??)

HSBT096 1PH(66) 2PM(??J TABLE 5 (Continued)

NAKE TaqI ϊbal HET.

TABLE 5 (Continued)

HSBT1012PK(22) 1PK144! B/10.2 9+7/16

KSBT103

KSET104

KSBT105 lPM(??i

KSBT111 IPM(ll) ?/3

HSBT113 1PM(22) 10/9.5

HSBT114110(33) 110(33) 110(33) ?/4.4 8.B/8+1.9 5.5/4.8 TABLE 5 Continued

TABLE 5 Continued)

TABLE 5 (Continued)

NAME BaiKI Bgll BgllI EcoRI EcoRV

MSBT114 2PK(22! ?/3.5

MSBT116

MSBT119

KSBT120 lPMdl) ?/7

MSBT121 1PM(33) 2PM(33) 5+5.B/10.B 5/5.4

TABLE 5 (Continued)

NAKE Hindlll Kpnl Mspl PstI PvuII

KS3T1143PK(22) 4PM(55) 8.7/10.. 5/4.7/7.2 5PM(55) 5/4.7/7.2

H3BT116 ??(??) 1PM⁽33⁾ 6.5/5.5

MSBT119110(55) 11/5.2

HSBT1202PK(44) 7.5/6.1

MSBT121

TABLE 5 Continued)

Although this way of classifying RFLPs gives a conservative estimate of the number of identified polymorphisms, for cosmids characterized by strong linkage disequilibrium, the number of ID events may be inflated at the expense of the actual number of PMs. To compensate for this, we performed a second set of calculations in which a polymorphic event must be detected with at least 3 enzymes to qualify as ID. RFLPs previously attributed to insertion-deletion events because detected with two enzymes, are now considered as two independent point mutations. 24 polymorphisms initially considered IDs fell into this category. Following this approach, 239 independent RFLPs were identified or 2.9 per cosmid, with now 87.9% of the PM type and 12.1% of the ID type.

Table 5 reports the observed heterozygosities obtained with the generated multisite haplotype systems. These values correspond to the percentage individuals heterozygous for at least one of the polymorphisms identified with a given cosmid. Noteworthy, this parameter is not affected by the mode of classification of RFLPs in PMs or IDs. At this point and without segregation information, we can't dissect the heterozygous genotypes into their component haplotypes. These heterozygosities were estimated on a small sample and should therefore be considered cautiously. As pointed out by Skolnick and White (129) , the main advantage of working with a sample of 9 individuals is that it is sufficient to identify the majority of useful polymorphisms. However, the mean heterozygosity of 51.9%, obtained over the 84 polymorphic cosmids demonstrates the power of the approach.

The following numbers of RFLPs were detected by each enzyme, irrespective of PM or ID type: TaqI: 57, EcoRI: 37, Mspl: 33, Hindlll: 31, PvuII: 30, EcoRV: 29, BamHI: 26, Bglll: 24, Xbal: 21, PstI: 18, Kpnl: 16 and Bgll: 13. The number of polymorphisms detected with Bglll and PstI were corrected to adjust for the lower number of probes used with these enzymes.

Proper interpretation of the polymorphic patterns has been confirmed by segregation analysis in pedigree material for most of the described RFLPs (see hereafter) .

RFLPs of the PM type were used to calculate nucleotide diversities as described in Materials and Methods. Two sets of values are reported, depending on which of the two criteria were used to classify an RFLP into the PM or ID type. Global nucleotide diversities of respectively 0.000652 and 0.000846 were obtained, meaning that a randomly selected Holstein animal will be heterozygous for approximately 1 every 1200 to 1500 base pairs. As expected because of the presence of an hypermutable cytosine followed by guanine in their recognition sequence, nucleotide diversities more than twice as high are obtained when combining data obtained with the enzymes Mspl and TaqI: 0.001493 and 0.002239 respectively (5) . On the other hand, the recognition sequence of the enzymes Bglll, Hindlll, PstI, PvuII and Xbal are devoid of hypermutable cytosines in the CpG dinucleotide and yield combined nucleotide diversities less than one third the values found with Mspl and TaqI (0.000492 and 0.000648). Using these two sets of values, one can extrapolate what nucleotide diversities would be obtained if sampling hypothetical sequences composed entirely of hypermutable cytosines, giving respectively 0.004496 and 0.007012. Assuming that the majority of detected polymorphisms behave according to the neutral mutation-random drift hypothesis, nucleotide diversity and mutation rate are simply related as: π « 4Neμ, where Ne stands for the effective population size and μ for the mutation rate (1) . Therefore, our data allow us to estimate that cytosines followed by guanines mutate at a rate approximately 10 times higher compared to other nucleotides, presumably because a substantial fraction of these are methylated in the germline and prone to mutate to thymidine by spontaneous deamination.

DISCUSSION

We demonstrate in this work that large numbers of

DNA markers with very acceptable Polymorphism Information Content can be quickly generated using large, randomly selected genomic probes in Southern blot hybridization experiments. The multisite haplotypes identified in this study using cosmid probes have a mean heterozygosity of 51.9% This value is of the same order of magnitude as the heterozygosities that we have obtained with a panel of approximately 40 bovine Variable Number of Tandem Repeat markers (mean heterozygosity 59%; 150), and with more than 50 bovine (TG)-dinucleotide microsatellites (mean heterozygosity 56%; unpublished) .

A remarkably high proportion of the tested cosmids proved informative: 74.5% of all tested clones, and as high as 85% when considering only the clones giving readable patterns. Compared to strategies aimed at isolating hypermutable sequences such as mini- or microsatellites, very little time and effort is wasted into candidate clones which have to be dropped at a later stage.

Because the cosmid clones used as probes are selected at random, we can reasonably assume that the coverage obtained with the generated markers is fairly uniform. Monte-Carlo simulations allow us to estimate that these 82 markers are covering 29%, 47% or 60% of the bovine genome in linkage studies if a maximum of respectively 5, 10 and 15 cM are scanned on each side of each marker, and assuming a total bovine map length of 25 Morgan as deduced from chiasmata counts (151) . The Southern blot hybridization procedure used for the detection of these RFLPs is a very mature and robust methodology, allowing the treatment of very large numbers of samples simultaneously, and benefitting from intrinsic "multiplexing" properties especially when using nylon membranes. Indeed, and despite variations between batches, we are routinely using membranes for 10 or more hybridization cycles.

The main disadvantage of multisite haplotypes is the requirement to use several restriction enzymes to fully exploit their PIC. This increases costs, amounts of required DNA, complicates the organization of genotype collection and their subsequent use in linkage analysis. The fact that 75 to 85% of the cosmids tested in cattle reveal polymorphism, compares favorably with results previously reported in the human. Schumm et al. (131) for instance report that 30% of the 1664 lambda clones they tested in a sample of 5 individuals, gave polymorphic patterns. Adjusting for the sample size and a ratio of approximately 2.5 between cosmid and phage insert size, the two figures are probably fairly similar. Surprisingly, only 54 of 101 human cosmid clones tested by the same group (152) were revealing RFLPs when tested with 9 restriction enzymes, versus 74.5% in our study with, however, 12 enzymes. It has been speculated that the relatively low level of polymorphism found in this study might result from a biais against human methylated sequences (including CpG present in the recognition sequence of TaqI and Mspl) when construction the cosmid library, due to the active modified cytosine restriction system ( cr) of the E.Coli 1046 host (152) .

These results are quite unexpected. Indeed, because of the population structure imposed by breeding strategies, the effective population size, Ne, in cattle is expected to be significantly lower than in the human. In .American Holstein, Ne is estimated between 10² and 2xl0³ (Ina Hoeschele, personal communication) . This value has to be compared with an estimated Ne of 10* in the human (18) . Assuming identical mutation rates, this reduction of Ne should be accompanied by a concomitant reduction in genetic variation. As a matter of fact, we obtain estimates of global nucleotide diversity between 0.000652 and 0.000846 which are between 3.5 and 2.5 times lower than values typically found in human populations (2, 119, 132). This confirms our previous results in another cattle population: the Belgian Blue Cattle breed (3, 4) .

At least part of the discrepancy between an apparently reduced nucleotide diversity but similar RFLP frequency, may be accounted for by the apparently higher frequency of insertion-deletion events found in cattle compared to human. Schumm et al. (131) report that 58 out of the 515 polymorphic loci (11.26%), show insertion-deletion type RFLPs; other groups report even lower frequencies of such events in the human (R.White, personal communication) .. In cattle, we found that 29 (35%) to 46 (56%) out of 82 polymorphic cosmids show such insertion-deletion events, depending on whether an ID-type polymorphism has to be detected with two or more enzymes. These results seems to point towards a fundamentally different property of both genomes. It is tempting to speculate that this high level of insertion- deletions in the bovine genome reflect the activity of a mobile element. Analysis of the restriction patterns characterizing these ID events, however, does not reveal any typical, recurrent "signature" of such an element.

Altogether, our laboratory has now isolated more than 200 DNA markers for cattle with a mean heterozygosity above 50%: 82 multisite haplotypes, 40 Variable Number of Tandem Repeat markers (150) and more than 80 dinucleotide microsatellites (unpublished) . The coverage of the bovine genome obtained with increasing number of randomly selected probes (0 to 500) , was estimated by Monte-Carlo simulation assuming that the used family material is sufficent to detect linkage at respectively 5, 10 and 15 cM, andg a total bovine map length of 25 Morgan as deduced from chiasmata counts (151) , divided over the 30 bovine chromosomes according to their relative length. With the PIC characterizing our marker set, we feel fairly comfortable that in the majority of situations we will be able to cover genetic distances of the order of 10 cM or more, especially if applying multilocus or interval mapping techniques (66, 68) . Therefore our panel of probes should cover around 75% of the bovine genome.

It is obvious that we are approaching a point where the efficiency of a strategy based on the further accumulation of random markers become questionable.

After 200 probes, the additional coverage obtained per new marker, expressed as a fraction of the maximum coverage possible, now is approximately 1/5 of the coverage obtained when we started this project. This creates the need for more targeted approaches. In this regard, mappers of domestic animal genomes will benefit from the human mapping efforts and the remarkable chromosomal conservation observed within mammals (133) . Based on comparative mapping information, it should be possible to identify genes likely located in the "holes" left by the random approach and to generate multisite haplotypes or microsatellite markers around their bovine homologues. We are presently exploring the feasibility of such approaches.

With the markers available today, a substantial part of the bovine genome is now amenable to linkage scanning, which will hopefully allow the mapping of

Economic Trait Loci and testing the feasibility of Marker Assisted Selection schemes. EXAMPLE 3

CLONING, CARACTERIZATION AND "IN VITRO" .AMPLIFICATION OF BOVINE MICROSATELLITES

INTRODUCTION Recently, microsatellites were proven to be an abundant source of highly polymorphic markers in the human (32-34) . As their name implies, microsatellites are minute VNTR markers (18-20) , characterized by tandem repetitions of very short repeats, one to four base pairs in length. Microsatellites exhibit levels of polymorphism comparable to VNTRs, but are much more abundant and apparently evenly spread throughout the genome.

We describe the cloning, caracterization and "in vitro" amplification of more than 100 such bovine microsatellites.

MATERIALS AND METHODS

l. DNA Database Search Bovine and ovine sequences in the EMBL and Genbank

(version 64.0) were searched for all types of dinucleo¬ tide and trinucleotide repeats using the Intelligenetics software, release 5.37. The minimum number of repeats was set at six. Six bovine sequences, characterized by the longest microsatellites, were retained for further analysis and are listed in Table 6.

TABLE 6

GBCYP21 GBIRBP

GBFSH GBKCAS GBGAPR GBPRLGR 2. Isolation of Bovine Microsatellites

Bovine genomic DNA was digested to completion with Mbol and size-fractionated by agarose-gel electrophore¬ sis. Fragments between 250 and 500 base pairs were recovered and purified using "Gene-Clean", ligated into the BAP-dephosphorylated BamHI site of pUC13 (Pharma¬ cia) , and cloned into 12. Coli DH5α cells (BRL) . The resulting clones were screened for the presence of (TG)_n microsatellites using a ³²P kinased (AC)₁₅ oligonucleotide as probe, and for (AG)n microsatellites using a (TC)15 probe. The library was made with female DNA to avoid the previously characterized Y-specific TG-rich bovine DYZ1 sequence (117) .

3. Sequencing of Bovine Microsatellites Positive clones were sequenced using one of the following procedures:

(a) Plasmid DNA was prepared using standard "boil¬ ing mini-prep" procedures and subjected to two chain- termination sequencing reactions using unmodified T7 DNA Polymerase (Pharmacia) , with the "universal" and "re¬ verse" sequencing primers, respectively. The ³⁵S labeled sequencing products were analyzed on standard denaturing polyacrylamide sequencing gels and detected by auto- radiography. (b) Magnetic solid-phase sequencing (137) . Alterna¬ tively, positive colonies were grown in microtiter- format using standard procedures in order to establish glycerol stocks and 5μl of culture directly subjected to PCR amplifications using the following vector-specific primers:

UNIBIS: 5'-GATGTGCTGCAAGGCGATTAAGTTG-3' REVBIS: 5'-CGGCTCGTATGTTGTGTGGAATTGT-3'

Two 30 cycle amplifications were carried out per clone, one with the UNIBIS primer biotinylated, the other with the REVBIS primer biotinylated. Denaturation was at 93^*C for 1 min. (except for the first cycle: 95'C for 5 min.) annealing at 60^*C for 2 min., and extension at 72^*C for 2 min. All of the PCR reactions were performed in micro- titer-format using the TECHNE MW-2 heating device. The biotinilated strand of the PCR-product was captured using the DYNAL streptavidin-coated magnetic beads according to the manufacturer recommended conditions and sequenced using unmodified T7 DNA polymerase (Pharmacia) as specified by the manufacturer.

4. Amplification and Detection of Bovine Microsatellites

(a) Simplex Amplification. The generated sequences are organized in the following way:

5'- (UP) (TG)_n -3'

3'- (AC)_n (DN) -5'

Suitable primers for in vitro amplification are identi¬ fied in "UPSTREAM (UP)" and "DOWNSTREAM (DN) " strands using the "OPTIPRIM" program designed by one of us. Given sequence information flanking a DNA stretch,

"Optiprim" helps the user to identify suitable primer pairs for PCR amplification of the corresponding DNA stretch.

Description of the program: The two DNA sequences flanking the DNA stretch to be amplified are referred to as the upstream (UP) and downstream (DN) sequence, res¬ pectively. Both for UP and DN, Optiprim tests all possible primers of given length (as defined by the user) and retains the primers (1) with melting tempera- ture (Tm) within the range defined by the user (Tm is calculated as 2C x number of As, or Ts + 4C x number of Gs or Cs) , (2) with a minimum percentage of each nucleo¬ tide as defined by the user, and (3) which cannot form secondary bonds that can be formed between two molecules of the defined primer when sliding them in antiparallel orientation against each other, as illustrated in the following:

5'-PRIMER-3' > < 3'-REMIRP-5'

n A facing a T contributes two hydrogen bonds, and a G facing a C contributes three hydrogen bonds. No loop formation is considered when performing this analysis. This generates two sets of selected primers: an UP set and a DN set. All possible pairs of one UP and one Dn primer are then tested. Optiprim retains the primer pairs if (1) the difference between melting temperatures of the two primers is within a range defined by the user, (2) the two primers cannot form secondary struc- tures, determined as for individual primers, except that now the UP primer is slided versus the DN primer. Using this program, 80% of the selected primer pairs were giving successful PCR amplification in our microsatel¬ lite systems. The following criteria are considered by "OPTIPRIM" when searching for primers: primer length, melting temperature and secondary structures that can be formed within and between primers. The selected primers are synthesized by phosphoramidite chemistry on Applied Biosystem synthesizers and used without further puri- fication. The microsatellites are amplified in vitro, in icrotiter plates and using the Teσhne MW2 device, in the following conditions (typically, 30μl reactions) : Target DNA 50 ng-lOOng KC1 50mM Tris-HCl, pH 8.4 lOmM

MgC12 1.5mM

Gelatine 0.01% dNTP 200μM each

Primers lμM each dCTP³² 2μCi/30μl

Amplitaq lU/30μl Thirty cycle amplifications are performed, characterized by a 93"C denaturation for 1 min. (except for the first cycle: 95'C, 5 min.), annealing at 55"C, 60'C or 65^*C for 2 min. depending on the primers, and extension at 72^*C for 2 min. Annealing temperatures are reduced by 5'C when using bovine primers on ovine target DNA.

(b) Multiplex Amplification. When performing multi¬ plex amplifications, concentrations of KCL, Tris-HCl, MgCl2, gelatine and dNTPs are increased by 50%, while the primer concentrations are decreased to 160μM each.

(c) Detection of Microsatellite Products. 2μl of PCR reaction are mixed with the same volume of formamide dye and run in a denaturing 7% acrylamide, 32% forma¬ mide, 5.6 M urea, 13.5 mM Tris, 4.5 mM Boric Acid, 250 μM EDTA gel. ³²P labeled products are detected by auto- radiography.

RESULTS AND DISCUSSION

1. Cloning and sequence caracterization of bovine microsatellites: A library of Mbol fragments between 250 and 500 bp was screened with the oligonucleotide probes. One out of 50 clones cross-hybridized. Assuming independent distribution of microsatellites and Mbol sites, the frequency of (TG)_n≥8 microsatellites in the bovine genome is estimated to be at >100,000. Table 7 summarizes the sequence information available for about 230 such bovine microsatellites. For each of these, sufficient sequence information has been gathered to generate the required primers for PCR amplification of the corresponding microsatellite. All sequences were generated by sequencing as described above or by screening GENEBANK. TABLE 7

Bovine Microsatellites

quence Identification Numbers

Repeat Down

2 3

5 6

9

11 12

14 15

17 18

20 21

23 24

26 27

29 30

32 33

35 36

38 39

41 42

44 45

47 48

50 51

53 54

56 57

59 60

62 63

65 66

68 69

71 72

74 75

77 78

80 81

83 84

86 87

89 90

92 93

95 96

98 99

101 102

104 105

107 108

110 111

113 114

116 117

119 120 122 123 TABLE 7 (Continued)

TABLE 7 (Continued)

TABLE 7 (Continued)

TABLE 7 (Continued)

TABLE 7 (Continued)

TGLA431 541 542 543

TGLA432 544 545 546

TGLA433 547 548 549

TGLA435 550 551 552

TGLA436 553 554 555

TGLA 37 556 557 558

TGLA438 559 560 561

TGLA44 562 563 564

TGLA441 565 566 567

TGLA443 568 569 570

TGLA444 571 572 573

TGLA445 574 575 576

TGLA446 577 578 579

TGLA 5 580 581 582

TGLA 7 583 584 585

TGLA48 586 587 588

TGLA49 589 590 591

TGLA5 592 593 594

TGLA51 595 596 597

TGLA52 598 599 600

TGLA53 601 602 603

TGLA54 604 605 606

TGLA58 607 608 609

TGLA6 610 611 612

TGLA60A 613 614 615

TGLA60B 616 617 618

TGLA61 619 620 621

TGLA66A 622 623 624

TGLA67 625 626 627

TGLA68 628 629 630

TGLA69 631 632 633

TGLA70A 634 635 636

TGLA70B 637 638 639

TGLA72 640 641 642

TABLE 7 (Continued)

TGLA73 643 644 645

TGLA75 646 647 648

TGLA76 649 650 651

TGLA77 652 653 654

TGLA78 655 656 657

TGLA79 658 659 660

TGLA8 661 662 663

TGLA80 664 665 666

TGLA82 667 668 669

TGLA84 670 671 672

TGLA85 673 674 675

TGLA86 676 677 678

TGLA89 679 680 681

TGLA9 682 683 684

TGLA9 685 686 687

TGLA98 688 689 690

TGLA99 691 692 693

TGLB84 694 695 696

2. PCR-Amplification and Detection of Microsatellites

(a) Simplex amplification

Table 8 reports a preliminary list of bovine micro- satellite systems that were successfully amplified in vitro. with the corresponding primer pairs. Note that pairs of primers selected by "OPTIPRIM", allow success¬ ful amplification in at least one of our standard con¬ ditions more than 80% of the time. Table 9 also gives the favoured annealing temperature (using the TECHNE MW2 heating device) . The mean heterozygosity for the bovine microsatellites was estimated at «50%.

TABLE 8 P_CR Amplified Bovine Microsatellites

Up Up Down Down

Sequence Primer Primer Primer Primer Name Name ID Name ID Annealing

AGLA13 AGLA13DN1 698

AGLA206DN1 700

AGLA206

AGLA209DN1 702

AGLA209

AGLA215 AGLA215DN1 704

AGLA217 AGLA217DN1 706

AGLA22DN1 708

AGLA22 710

AGLA226 AGLA226DN1

AGLA234 AGLA234DN1 712

AGLA25 AGLA254DN1 714

AGLA255DN1 716

AGLA255

AGIA258 AGLA258DN1 718

AGLA260DN1 720

AGLA260

AGLA269DN1 722

AGLA269

AGLA284 AGLA284DN1 724

AGLA285DN1 726

AGLA285

AGLA29 AGLA29DN1 728

AGLA291DN1 730

AGLA291

AGLA293DN1 732

AGLA293

AGLA8 AGLA8DN1 734

GBFSH GBFSHDN1 736

GBIRBPDN1 738

GBIRBP

GBKCASDN2 740

GBKCAS

MGTG1DN1 742

MGTG1

MGTG13BDN2 744

MGTG13B

MGTG3DN2 746

MGTG3

MGTG4BDN2 748

MGTG4B

MGTG7 MGTG7DN3 750

TGLA10DN1 752

TGLA10

TGLA111DN1 754

TGLA111

TGLA116DN1 756

TGLA116

TGLA117 TGLA117DN1 758

TGLA12DN2 760

TGLA12

TGLA122DN1 762

TGLA122

TGLA123DN1 764

TGLA123

TGLA124DN1 766

TGLA124

TGLA125DN2 768

TGLA125

TGLA126DN1 770

TGLA126

TGLA127DN1 772

TGLA127

TGLA128DN1 774

TGLA128

TGLA130DN1 776

TGLA130 TABLE 8 (Continued)

TGLA132

TGLA134

TGLA137

TGLA142

TGLA147

TGLA15

TGLA153

TGLA158

TGLA159

TGLA164

TGLA170

TGLA176

TGLA182

TGLA203

TGLA206

TGLA210

TGLA214

TGLA215

TGLA22

TGLA227

TGLA23

TGLA231

TGLA245

TGLA260

TGLA263

TGLA28

TGLA303

TGLA304

TGLA307

TGLA309

TGLA322

TGLA325

TGLA327

TGLA328

TGLA334

TGLA337

TGLA339

TGLA34

TGLA340

TGLA341

TGLA342

TGLA346

TGLA35 TABLE 8 (Continued)

TABLE 8 (Continued)

(b) Multiplex Amplification

To increase the speed and lower the cost of geno¬ typing, multiplex approaches for both amplification and data capture of microsatellites are utilized. Micro- satellite systems yielding products of non-overlapping size were coamplified as described above. Preliminary results show that at least four different systems can easily be coamplified in these standard conditions. The following multiplex amplifications, for instance, were shown to yield consistent, easily interpretable results:

a. GBCYP21 - TGLA10 - TGLA 44 - TGLA116 b. TGLA9 - MGTG4B - TGLA23 - TGLA35 C MGTG3 - MGTG13B

By limiting detection to a single detection procedure (autoradiography of ³²P-labeled product) , multiplex amplification is limited to systems yielding products of non-overlapping size. To overcome this limitation, alternative detection schemes are utilized. In particu¬ lar, the use of confocal microscopy to detect products labeled with laser-excitable fluorescent molecules (such as fluoresceine, rhoda ine, ...) is used. The products can then be differentiated based on the specific excita¬ tion and emission spectra of the tagged fluorescent molecules. Using this approach detection of up to at least 20 different systems should is feasable.

3. PCR-mapping of Bovine Micro-satellites Using Somatic Cell Hybrids

Results of the concordancy analysis are summarized in Table 9. Synteny groups to which microsatellite systems most likely map as deduced from concordancy analysis are underlined. Clear-cut results were obtained for MGTG13B (U19 or chromosome 15) , TGLA6 (Ull) , TGLA9 (U27) , TGLA11 (U16) , TGLA22 (U26 or chromosome 26) , TGLA23 (Ull) , TGLA36 (U27) , TGLA52 (U9 or chromosome 18) . Results are less discriminating for the other systems. Most likely synteny groups are, however, mentioned. In addition, we know from the literature that GBKCAS maps to U15 or chromosome 6, and GBCYP21 to U20 or chromosome 23.

TABLE 9

Concordancv Analysis for Synteny Mapping of Microsatellites

I

H

TABLE 9 (Continued)

Concordency Analysis for Synteny Mapping of Microsatellites

EX.AMPLE 4 CONSTRUCTION OF A PRIMARY BOVINE DNA MARKER MAP.

Bovine pedigrees for a total of approximately 200 individuals were genotyped for 150 of these markers as described. Pair-wise linkage analysis was performed using the LODSCORE program. Only lodscore values superior to 3 were considered significant. This generated a primary DNA marker map with 24 linkage groups counting two or more markers (15 assigned to specific chromosomes or synteny groups) , and 68 singleton markers. Table 10 summarizes our findings. Linkage groups were assigned to specific chromosomes or synteny groups whenever that information was available.

TABLE 10 Primary Bovine DNA Marker Map

TABLE 10

E 10 Continued

TABLE 10 Continued

CHR./SYNT.

CHR./SYNT. : Chromosome or synteny group LG: Linkage group

CONCLUSIONS Samples of E_j_ coli harboring clones of polymorphic bovid markers have been deposited on 17 January 1991 with the .American Type Culture Collection (Rockville, Maryland) under accession numbers 68,514 and 68,515. Deposit of the clones is for the sake of completeness, but is not intended to limit the scope of the instant invention to said deposited materials. Access to said cultures will be available during the pendency of the application to those determined by the Commissioner of Patents and Trademarks to be entitled thereto. All restrictions on availability will be removed upon grant of the application and said cultures will remain avail¬ able during the life of the patent. Nonviable or destroyed cultures will be replaced in kind.

It will be appreciated that the methods and com¬ positions of the instant invention can be incorporated in the form of a variety of embodiments, only a few of which are disclosed herein. It will be apparent to the artisan that other embodiments exist and do not depart from the spirit of the invention. Thus the described embodiments are illustrative and should not be construed as restrictive.

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152. BOWDEN, D.W. et al. (1989). J. Human. Genet. 44:671-678. SEQUENCE LISTING

(1) GENERAL INFORMATION:

(i) APPLICANT: Georges, Michel Massey, Joseph M

(ii) TITLE OF INVENTION: POLYMORPHICDNA MARKERS IN BOVIDAE

(iϋ) NUMBER OF SEQUENCES: 952

(iv) CORRESPONDENCE ADDRESS: (A) ADDRESSEE: Venable, Baetjer, Howard &

Civiletti

(B) STREET: 1201 New York Avenue N.W. , Suite 1000

(C) CITY: Washington (D) STATE: DC

(E) COUNTRY: USA

(F) ZIP: 22205

(V) COMPUTER READABLE FORM: (A) MEDIUM TYPE: Floppy disk

(B) COMPUTER: IBM PC compatible

(C) OPERATING SYSTEM: PC-DOS/MS-DOS

(D) SOFTWARE: Wordperfect 5.1 (vi) CURRENT APPLICATION DATA:

(A) APPLICATION NUMBER: WO

(B) FILING DATE: 15-JAN-1992

(C) CLASSIFICATION: (VU) CURRENT APPLICATION DATA:

(A) APPLICATION NUMBER: US 642,342

(B) FILING DATE: 15-JAN-1991

(C) CLASSIFICATION: (vϋi) ATTORNEY/AGENT INFORMATION:

(A) NAME: Ihnen, Jeffrey L

(B) REGISTRATION NUMBER: 28,957

(C) REFERENCE/DOCKET NUMBER: 18681-91367 (ix) TELECOMMUNICATION INFORMATION:

(A) TELEPHONE: 202-962-4810

(B) TELEF.AX: 202-962-8300 -I2S-

(2) INFORMATION FOR SEQ ID NO: 1:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA13 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 1:

GGCGAGCTCGAATTCTTACTCTTCTGTTTCCTTTGTTTAAATCAA (2) INFORMATION FOR SEQ ID NO: 2:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA13 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 2:

TATCTATCTATCTGTGTATATATGTGTGTGTGTATATATATATATATATA AAGAGAGAGAGAGAGAGAGAGAGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 3:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -12

(iv) .Z-NTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA13 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 3:

AACCAGCACCATGGAAATTCTCAGTCCACTGAGTAGTACTGATAAAATGT (2) INFORMATION FOR SEQ ID NO: 4:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 142 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA1 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 4:

TGCTCCCTGTTAGCAATGGGATGTGAAAAGCTGAAAAAAGGTACAGAGAT GCTCTGTCCAGTATGAGAGCCACATATGACTGTAAAGCCCCTGAAATAGA CCTAGTCTGAACCGAGACGCACACAAGGATGTGAACTGTTGT

(2) INFORMATION FOR SEQ ID NO: 5:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA17 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 5: AAAAAGAAAAAAAGAGAGAGAGAGAGAGAGAG -i3θ-

(2) INFORMATION FOR SEQ ID NO: 6:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 189 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA17 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 6:

TTCCCAACCCAGGGATCAAACCCAGGTCTCCTGCACTGCAGCTGATTCCT TACCATCTGAGCCACGAGGGTAACCTAATGTGGGCCAAACAGGTAGTTTA AAATTTTCTAGTAACCATGTTAAATAAGTAATTCAATCAATTATAATATA TTTTCTTTAACCTAATAATCCAATGTATTATCATCT...

(2) INFORMATION FOR SEQ ID NO: 7:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA206 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 7:

TTACAATATATCAAAGTATCTGTTGTAATATTTAGACTCATAAGATGGAA CACTACAGACC

(2) INFORMATION FOR SEQ ID NO: 8:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 14 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA206 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 8: AAAAAAAAAAAAAA (2) INFORMATION FOR SEQ ID NO: 9:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA206 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 9:

AAAGACTCAGAAAGAAGGCTGTGTCCCAAGGGCAATGAGTGA (2) INFORMATION FOR SEQ ID NO: 10:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA209 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 10: -.32-

GGGAGTAAGCCAGACAGCCTGATGGAGACAGAGTCAGAGACAAAGAGACC TGGCTGCCAAATTCCCCCTCATCTCCTAC

(2) INFORMATION FOR SEQ ID NO: 11:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA209 (repeat)

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 11: AGAGAGAGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 12:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA209 (down)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 12: AGCTGCTTCTGCCCATCCCTTTATT (2) INFORMATION FOR SEQ ID NO: 13:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA212 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 13:

GTGATTTTCTTGTTTAAACAATTCCTGCTTAAAGACGCCACTT (2) INFORMATION FOR SEQ ID NO: 14:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA212 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 14:

AAAAAAAAAAAATCCAGACATAGAAACCACAGAGAGAGAGAGAGAGAGAG AGAGAGAGAGA

(2) INFORMATION FOR SEQ ID NO: 15:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 73 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA212 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 15:

GGCGGCTCTGTCTTTAGTTTCAAAATTATTATAAAAAATTCATCTGTGGT H ^μ

TTATTTTTAGGGTCATCCTTCCT (2) INFORMATION FOR SEQ ID NO: 16:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 96 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA215 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 16:

CACAGGTTGCATGCTTAGGATAAGGACCAGGCCTGAATGTCCTGAGGCCA GTCTGAGAGACTAACATGAGATAGCAACCCAAACTGTGAGACAGCC

(2) INFORMATION FOR SEQ ID NO: 17:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA215 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 17:

AGAGAGAGAGAGAAAAAAAAAAAAAAAGAGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 18:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) -J35-

(iv) .z^NTI-SENSE : NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA215 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 18: AGCTTTTCGTGGGAAAGT (2) INFORMATION FOR SEQ ID NO: 19:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA217 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 19:

AGTGGTTGCCATTTCCTTCTCTAATGCATGAAATGTGAAAACCACTAGCC AGACTCATAAAG

(2) INFORMATION FOR SEQ ID NO: 20:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA217 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 20: AAAAAAAAAAAGAGAGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 21:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA217 (down)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 21:

CCTTTAACTTCTCCTGTTCCATGTTTAGTTTTATCGATTTGAG (2) INFORMATION FOR SEQ ID NO: 22:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 57 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA218 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 22:

AAGATGAATGGAGGTTGCACCATCTCCTGGAAGGGAAACCGGACTGGCTA AACAGTC

(2) INFORMATION FOR SEQ ID NO: 23:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA218 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 23:

GAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACAGAGAGACAGAG (2) INFORMATION FOR SEQ ID NO: 24:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA218 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 24: TGTCTTCTGCCTAGACCTCAGGGAATTGTTGAGTTAA (2) INFORMATION FOR SEQ ID NO: 25:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 130 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINS SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA22 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 25:

TGCACAGACTGCGTTTTTCATGTCAAGTGAGATGAGAGCCTCTGGAGGGT TCTGAGCTAAGAACTGGGCTTAAACATTGTATTCAAGACAGGCTTCAGGT GCGGGGGGCAGAGTTAGGAATCCAGGA...

(2) INFORMATION FOR SEQ ID NO: 26: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 96 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA22 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 26:

GTGTGTGTGTGTGTGTGTGTGTGTGGAGAGAGAGAGAGAGAGAGAGAGAG AGAGAGAGAGAGAGAGAGAGAGAGAGAGNNNNNNNNNNAGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 27:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA22 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 27:

CCACTGCCCACTTTCCACCATCAAACTGCCCCTACAGAGTCTACTTCGTC ACCTAATTCATCACTCTCTCAGCTACA...

(2) INFORMATION FOR SEQ ID NO: 28:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA220 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 28:

CCTGACTCATTGGAAAAGACCCTGATGCTGGGAAAGACTGAGGGCAGGAG GAGAAGGGGACAACAGAAGATGAGATACTTGGATGGCATCACCGACTCAA TGGACATGGGTTTGGGTAGACTCTGGCAGTTGGTGATGGATAGGGAGGCC TGGTGTGCTGCAGTTCATGGGGTCGCAACAGCCAGACATGACTGAGCGA

(2) INFORMATION FOR SEQ ID NO: 29:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA220 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 29:

AACTGAACTGAACTGAACTGAACTGNNNNNNNNNNNNNNNNNNNNNNNNN (2) INFORMATION FOR SEQ ID NO: 30:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 124 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA220 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 30:

AACTCCAGCCCTTCTCCCACCTCGCTGAGTGGCAAACAGGCTCTGCAGGC AGACAGATGGCATTTAAATTTTGCTTCTGTCACTTGCCAGCCCAAGCTCA TGCAAGTTACTGATCCTTGCTGGG (2) INFORMATION FOR SEQ ID NO: 31:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 101 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA223 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 31:

AAATTATAGACTTCACTTGGGACAATGTCTGTGTTGAATGAATGAGTCAG TCATTTTCCATGCAAAGATAAATGTCGCATCACCTCTAAATTATGGCATG G

(2) INFORMATION FOR SEQ ID NO: 32:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA223 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 32: (TC) 3TTAGG(AG)2AA(AG)2ACTG(AG) ... (2) INFORMATION FOR SEQ ID NO: 33:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA223 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 33: CCTTTGACTCATTACCGTATAGTGCTCC (2) INFORMATION FOR SEQ ID NO: 34:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 87 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA226 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 34:

GATGACTGAAGGGAAATAATTTTCTTCAGTTTTCTGAACCAATNGCTAAA GAAATGCAGTGTTGTCAGCCAAGCCAAGAATCAGGGA

(2) INFORMATION FOR SEQ ID NO: 35:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA226 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 35:

GTGTGTGTGTGCATATGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGA -1^2-

GAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 36:

(i) SEQUENCE CH.ARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA226 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 36:

GCTTAACAAGCCATGCTGAATGGTCTTATGTGATTTGATTTAACAT (2) INFORMATION FOR SEQ ID NO: 37:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA227B (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 37:

AGCTAGCAAGGATCTACTGGGTAGCACAGGAAACTCTACTCAATATTCTC TAATGACCTACATGG

(2) INFORMATION FOR SEQ ID NO: 38:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 73 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA227B (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 38:

AAAAATAATCTAAAAAAGAGGGGATATATGTATATATACATTGTATATAT ATATTGATATTGATATATATACA

(2) INFORMATION FOR SEQ ID NO: 39:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA227B (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 39:

ATTTATTAGAGCATAGTTGATTTAAAATGCTGTGTTTTTGCTGTACATCA AAGTGAATCAAT

(2) INFORMATION FOR SEQ ID NO: 40:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA230 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 40:

AATCCTATGGACAGAGGAGCCTGGCAGGTTACATTCATTGGGGTCACAAG A -M-

(2) INFORMATION FOR SEQ ID NO: 41:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA230 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 41: AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 42:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 105 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA230 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 42:

TGTACTGGTTCTCTGCAGGCCCTGTGTCCACTGCGAAGACAGAGTTCCAT GGCTTCTTGAGGTTCTAGGAGGAGTCTATTTGACTTGAGATGCGATTTTT CCACA

(2) INFORMATION FOR SEQ ID NO: 43:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 120 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA232 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 43:

AAAATCCACATGCCTTTGCAAATACCTCCTGACCAGTCCCCCTCGGTTCT CCACAGCCCTTGCCACACCGATGCAGACGTACACGACGATGGATAAAAAC TCGATTTATCCATCATCGAA

(2) INFORMATION FOR SEQ ID NO: 44:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA232 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 44: AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 45:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA232 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 45: G.AATTCCAGCGAAATGGTTCTACATTTGCTAGGTGTCCT (2) INFORMATION FOR SEQ ID NO: 46:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA233 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 46:

TGATAGAAATTCCCAGATGATAACTCAGATGTGAAAGCACTGTGCAAACA TCCACGTAGCATAAATACCTCTGAGCATAC

(2) INFORMATION FOR SEQ ID NO: 47:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 7 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA233 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 47: (AG)+++ (2) INFORMATION FOR SEQ ID NO: 48:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA233 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 48:

GGCCCAGGGTTGGTCCCAAATGGCATGAACAGCCAATAGTGTCATCAGGC ATTA

(2) INFORMATION FOR SEQ ID NO: 49:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA234 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 49: CTTGCTTTAGATTTATTTATTCATTTGTGATGCA (2) INFORMATION FOR SEQ ID NO: 50:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA234 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 50:

GTGTGTGTGTGTGTGTGTGTGTGAGGAGAGAGAGAGAGAGAGAGAGAGAG -14s-

AGAGAG (2) INFORMATION FOR SEQ ID NO: 51:

(i) SEQUENCE CH.ARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA234 (down)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 51:

AAATCTTTGTATCCCCACCATTATACACAAAGTTTTTCCATGGAGTACAT GCTCACCTGCTAGTG

(2) INFORMATION FOR SEQ ID NO: 52:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA243 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 52:

AGCTTAGGCAAATCAGTGTTACATCTCCATTTTATTTAGAAGATAGCAGG (2) INFORMATION FOR SEQ ID NO: 53:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -145-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA243 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 53: AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 54:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 83 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA2 3 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 54:

TGCATAGGCAGGCCCAGGTGGAGGAAAAAACATATAAAAGGAGGAGCCAA AGCGCTTTCTCACGGACTCTCTCCCGCGTGCAT

(2) INFORMATION FOR SEQ ID NO: 55:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 92 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA247 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 55:

ATAAACCAAGGATCAGTAAATATTTTCTGTAAAGGTGTGATAATAATATT TAGAATTTGTAGGTCACATACAGATTCTATCACATAGGTTTG -ISO-

(2) INFORMATION FOR SEQ ID NO: 56:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA247 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 56:

(2) INFORMATION FOR SEQ ID NO: 57:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA247 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 57: ATCAAGGATGGATTTACATTTTAAAGCATTGTTT (2) INFORMATION FOR SEQ ID NO: 58:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - — J Sj-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA248 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 58: AACCAGTAGGCAAAACTCAATGACTCGTAAGAGAATGG (2) INFORMATION FOR SEQ ID NO: 59:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

( ii) IMMEDIATE SOURCE:

(B) CLONE: AGLA248 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 59: ANAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 60:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 152 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA248 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 60:

AACCCTGATGGATGCTCACCTACAGACCCTGATGTATTTCTTCCTCAGAA ATTTCTCCATATTAGGGGTGTCATCCACAACTGTCACTGTACCCAAATTC CTTATCACCATTACTACAGGAGAGAAAACCTTTTCTTTTACTGATTGTAT GG (2) INFORMATION FOR SEQ ID NO: 61:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA254 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 61: AGCTGCTTGGCACAGGCAAAAA (2) INFORMATION FOR SEQ ID NO: 62:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 7 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA254 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 62: (AG)+++ (2) INFORMATION FOR SEQ ID NO: 63:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 119 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO -.53-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA254 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 63:

TTGCCTCCTTTATTACAGATTAATTGACCATAAATGTGTGGATTAATTTC TGGACTCTGTATTCTGTGCCATTAATCTCTGTGTCCTTTTTTTTTTTCTT TTGTTCCAGTGCCATACTT

(2) INFORMATION FOR SEQ ID NO: 64:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA255 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 64:

AAATCTCAATTTCCTCATCGGTAAAATGGGGATAATAATTCCTGATTTGC AGGGTTGTTGTGGTAATTAAATG.AAACTGG

(2) INFORMATION FOR SEQ ID NO: 65:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA255 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 65:

TGTGTGTGTATGTGTGTGTGTAAAAGAGAGAGAGATTTCGAGAGAGAAAG AGAG 5ψ-

(2) INFORMATION FOR SEQ ID NO: 66:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA255 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 66:

CACCGGCAGGATGGGAAAGTGCACAGAGAACGGAAGACCATTAAACACCT CCTCCATGTCAGGGG

(2) INFORMATION FOR SEQ ID NO: 67:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 19 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA257 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 67: AGCTAGATTAACACCAAAA (2) INFORMATION FOR SEQ ID NO: 68:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO A55-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA257 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 68: AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 69:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA257 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 69:

TTGGTGTGTAATTGTTCATACTGATCTCTTAGAATCNTTTGTAATTCCAT GTATCAGTTGTAATG

(2) INFORMATION FOR SEQ ID NO: 70:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 90 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA258 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 70:

CAGAGACTTTTCATTCTGAGGAAAAACCTCCAGAAAGCCATATTCCATCT CTGGTGGCCCATATTCCATCTCTGCTGACTTCTCATAAAC

(2) INFORMATION FOR SEQ ID NO: 71: -I5V

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 86 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA258 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 71:

TGTGTGTGAGAGAGAGAGAGAGCAAGAGAGACAGAGAGACAGATGAGAGA AGAGAGACAGAGAGGCATACAGTAGAGTTTGAATAT

(2) INFORMATION FOR SEQ ID NO: 72:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 134 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA258 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 72:

CCTCAGAACACAGAGAAGAGAAAACTGGGTCCTTGATGGGAAACAGCAGG GGACTGCGGGGTATGGACAATTAATTTTGAAATCCAGGACAATGACAGAA TTGTTGCTTCATTGTGGCTTTCCCAATATTCAAA

(2) INFORMATION FOR SEQ ID NO: 73:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 147 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -IS? -

(iv) .ANTI-SENSE : NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA259 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 73:

AACCAGATCTCCTGAGTCTCTTGCATTGGCAGGTGGATTCTTTCCCACTT AGCCACCTGGAAGCCCTGCTTCCATCCATGGGATTTTCAAGGCAAGAGTA CTGGAGTGGGGTGCCATTGCCTTCTCCAGTAAAGAGTAAATAAC...

(2) INFORMATION FOR SEQ ID NO: 74:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA259 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 74:

AGAGAGAGGGAGAGCGGGAGAGCGGGAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 75:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA259 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 75: GTCAGGATATTGCAATTTTAAGTGTCCTTTAGTT (2) INFORMATION FOR SEQ ID NO: 76:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 168 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA260 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 76:

GTATGACTAAACACTCCCATTGCTTTATTAATGCCCTGTGAATGGGTTAA GCATTTTGGACAAAATTCACTAATGTTTTTAACCGACCAGAGATTACATA TAATCATTCAGATAAGTCAATCAGCAATCCTCAATTTTACCTTCTGACCA TGACCTTGTGTACTT...

(2) INFORMATION FOR SEQ ID NO: 77:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE:- DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA260 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 77:

GAGAGAGAAAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA GA

(2) INFORMATION FOR SEQ ID NO: 78:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 123 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) 59-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA260 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 78:

CCTGGAGGCCTTTGGACTTAATTGCAACATCAGTTCTGCCCTGGGTCTCA AATCTGCCGGCCTGCCCTGAAGATTTTGGACTTACCATTTCTCTGTAATT ACATTAGCCAGTTCCTTAAA...

(2) INFORMATION FOR SEQ ID NO: 79:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 74 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA267 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 79:

AGCTTGGTGTTCTATAATCCATGGGGTTGCAAAAGGATCGGACATGGCTT AGCAACTAGACAACTAAACAG...

(2) INFORMATION FOR SEQ ID NO: 80:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA267 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 80: -4 - O-

AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 81:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 138 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA267 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 81:

CCTGAATCTCGGTTCCCCTTCTCTTCAAAGTAGTGACTTTCAGCCCAGAT CCCTGCAATTTCTTCAAAGTTCACATTACTTCCTCACAAAGTATGATTGG ACATAGGAAGAACTTTTTCTGAGTGTGTATTGGTG...

(2) INFORMATION FOR SEQ ID NO: 82:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA269 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 82: CTTTCAATGTATTTGCTTATTTGTTCAACTG (2) INFORMATION FOR SEQ ID NO: 83:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA269 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 83:

AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 84:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 147 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA269 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 84:

CCTGACACTAGTAGATTTGAAACCCATGTGTGTAATTTGCTATTTTCAGG TTAAAGAATAAAAGACTTGTACACAAATACTGTACACTAATTGCCAAACT TGTTTTTCCATAGAAGTGTGGGTTCAGAAACCTCTCCAAGCCCCAAA

(2) INFORMATION FOR SEQ ID NO: 85:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 84 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA272 (up) -462-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 85:

CTTGTTTTTTTCTATTCAGTTTTATGAGTTCTACTTTGAATATTAACTCT TTATCACATATGATTTGCAAAATTTCCCATTCTA

(2) INFORMATION FOR SEQ ID NO: 86:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA272 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 86: TCAGTTCAGTTCAGTTCAGT (2) INFORMATION FOR SEQ ID NO: 87:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY:, linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA272 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 87:

CCCGGCATGCTGCAATTCATGGGGTCGCAAAGAGTTGGACACAACTGAGT G

(2) INFORMATION FOR SEQ ID NO: 88:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA280 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 88:

AGCTCTTATGCTCAAAGTTGTCCTCAGAGAGGGGTCAACTGGGATTCAAA TATAGGAACAGCAA

(2) INFORMATION FOR SEQ ID NO: 89:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 84 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

( ii) IMMEDIATE SOURCE:

(B) CLONE: AGLA280 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 89:

AGAGAGAGAGACAGAGAGAAACAGAAAGAGACAGAGAGAGAGAGACAGAG AGAGAGAGAGACACACAGAGAGAACACACACACA

(2) INFORMATION FOR SEQ ID NO: 90:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA280 (down) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 90:

GAATTCAGAAGGTGTGGGTGGAGGAGACAGACCAAAAACACT (2) INFORMATION FOR SEQ ID NO: 91:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA284 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 91:

TGCAGTTTCATAACTGTACAGCAGTCATGGACAGGTCAAATCCAGG (2) INFORMATION FOR SEQ ID NO: 92:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 3 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA284 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 92:

(2) INFORMATION FOR SEQ ID NO: 93:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA284 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 93: GTACCAGTGACATTCAGAGGAGCACCAACAAT (2) INFORMATION FOR SEQ ID NO: 94:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA285 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 94:

CTTAAAAGACCAAGGCACAAAAGGCTTCCTGCCAATCCCATTAAAGTTGA AGGCAGAGGATTTTG

(2) INFORMATION FOR SEQ ID NO: 95:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA285 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 95:

AAAAAAAAAAAAAAAGAGAGAGAGAGAGAGAGAAAGAGAGAGAGAGAGA

(2) INFORMATION FOR SEQ ID NO: 96:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA285 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 96:

AGCACCCTTCTTGACCTGCAACAGGCATGCAGGGNNTCATTTTGATNAGC ACTGAACAAATT

(2) INFORMATION FOR SEQ ID NO: 97:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA29 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 97:

ACAGGAAGCCGAGTGAGATATGTAAGCCAAAACTCAGACAGGTGGAGTAG AGGA

(2) INFORMATION FOR SEQ ID NO: 98:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - lfc7-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA29 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 98:

GTGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA GAGAGAGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 99:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA29 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 99:

TTCACATTACAGCCTGTGTGAATGTCCTCTATGACCTGCCTGGAGGA (2) INFORMATION FOR SEQ ID NO: 100:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 129 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA291 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 100: -IG 8-

CTGGCCAGTTTTGAAGGATAAAATAAGTGTTTTAGCAAACAACCAAAATT CCTTAATGCCATTGTCAAAGAAACACAGTATTTTCTCTCAAATGATGAAT ATGCTTCTATGAAATTACTTTGCTGG...

(2) INFORMATION FOR SEQ ID NO: 101:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA291 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 101: AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 102:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA291 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 102:

GGCTGTTCTGCCTTTTCCAACAAGTTAGACTAAACTTTCTAGGACTATTC TATGCATGCCTCTCCAG

(2) INFORMATION FOR SEQ ID NO: 103:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear 469-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA293 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 103:

AGGGCAAGGGAGAGAAACTCAACCCAAGACAACTCAAGTCAAAGGACCAA GACTGAGAACCCA...

(2) INFORMATION FOR SEQ ID NO: 104:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 72 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA293 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 104:

AGAGAGAGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGTGT GTGTGTGTGTGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 105:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 83 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA293 (down) 47c-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 105:

CTACCAATGACTTTATTCTCCACCTAGCAGAAAAGTCCAGTCTGAAATTG GAGGCAATGAGGCAAATATTCAAAGAGAAN...

(2) INFORMATION FOR SEQ ID NO: 106:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 75 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA296 (up)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 106:

CTGGTTAAATGAAATTCCATAAACTGCTCACAAATTGAAAAAAAACTTAC ACTTGGATAACTAAATCATGTAATA

(2) INFORMATION FOR SEQ ID NO: 107:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA296 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 107:

GTGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA GAGAGA

(2) INFORMATION FOR SEQ ID NO: 108:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single D TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA296 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 108:

GTAGAAAATTAGGTGTATCAAGGATTATTACATGAGCGT...CTCAAAAA TAGTAAGTACCCACTCA

(2) INFORMATION FOR SEQ ID NO: 109:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA298 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 109:

CAGTTCCTGATGAGAATCCTTTCCTTGCTTGTGGATGTCTACTGTGTCCT TACATGGC

(2) INFORMATION FOR SEQ ID NO: 110:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA298 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 110: AGAGAGACAGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 111:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA298 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 111:

CGTAAAGGTAGTGCCCTGAACCCATAGACCTAGTTTCCTTACATAAAAAG GAACAGAAACCAGA

(2) INFORMATION FOR SEQ ID NO: 112:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL*: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA299 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 112:

AGTAGGAAGAAAAACCAGAACTAAGGAGTTGGCTGTTGTATGAACATGAT GTAGAGGAG

(2) INFORMATION FOR SEQ ID NO: 113:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 57 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear H73-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA299 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 113:

AAAGCAAAAAAAAAAAAAAAAAAGAGAGAGAGAGAGAGAGACAGAGAAAG AGAGAGA

(2) INFORMATION FOR SEQ ID NO: 114:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA299 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 114:

AAGATTTTTGAGAAAAATGTTTATTCAACTCGAAGTTGATCTTAAGACAC AGCCATTAACAAACCTT

(2) INFORMATION FOR SEQ ID NO: 115:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 120 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA300 (up) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 115:

TCTCCAAGTCTGTCATTGCCTTAGGGTGCTCCAGCATCCATTCCATTTTG CAAAATATTAATTAGCCCTTTCATTTTGGACACAGTAACTGCTGTCTACC TATTCTCACAGTGTTAA...

(2) INFORMATION FOR SEQ ID NO: 116:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA300 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 116:

AGAGAGAGAGAGAGAAAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG AGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 117:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA300 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 117:

AGCTTTCTTCACAGTCCAACTCGTGGGTGAGTAGGTAATTACAAATGCTG CTGTTTGTCATCACAGTTGTTATAGA

(2) INFORMATION FOR SEQ ID NO: 118:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs B) TYPE: nucleic acid (C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA33 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 118:

TGCAGGGAAGTCCCTACAATATTCTTTAACCGAGTGTCCATCAAAGCTGA TCAATCGTCATG

(2) INFORMATION FOR SEQ ID NO: 119:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA33 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 119:

AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 120:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: (B) CLONE: AGLA33 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 120:

ATGTAGCTAGACATATTTCTTAAATTTCTCGTTGCAGGACAGTTTCTCAG ACTT

(2) INFORMATION FOR SEQ ID NO: 121:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA8 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 121:

AAAGTGATGCATCTTTTGAAACAAAAGTTTCCATCTTTATACTTGCCACC AAGCCATTTTATCT

(2) INFORMATION FOR SEQ ID NO: 122:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA8 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 122:

TGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAG (2) INFORMATION FOR SEQ ID NO: 123:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 57 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single -!77_

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA8 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 123:

GAGGGGCCTGGAGNGTATAGAACATGGGGTCACAAAGAGTCAGACACAAC TGAGCAG

(2) INFORMATION FOR SEQ ID NO: 124:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 121 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBFSH (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 124:

CTTTATGGGGTGGTAAATGAGTTTGACCAAAATCCACTTATCACATCTTC TTGGGATATAGACTTAGTGGCATGATATTGAAATAACTTAAACAGAAGTA ACAACTTTTCCCTCAGTGCAA

(2) INFORMATION FOR SEQ ID NO: 125:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus 8-

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBFSH (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 125:

ATATATATATATATATATATATATATATATATATATATATTTTTTTTTTT TTT

(2) INFORMATION FOR SEQ ID NO: 126:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 120 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBFSH (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 126:

AGACATCTCTCCACCTTGAAGCCTATATATTTTGCACAAGTCACAGTTTC TAAGGCTACATGGTTTGTACATAAGAACTTTAATCCTTGTAGAATAGGTT TTTTTGTAGCACTTTCTAGT

(2) INFORMATION FOR SEQ ID NO: 127:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 57 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBIRBP (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 127:

TAGACCTATTGCCATACAGACAAATGTATGATCACCTTCTATGCTTCCAC TCTAGGA

(2) INFORMATION FOR SEQ ID NO: 128:

(i) SEQUENCE CHARACTERISTICS: -175-

(A) LENGTH: 85 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBIRBP (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 128:

CTCTCTCTCCTCCCTCTTCTCTCTCTCTCACATACATACACACACACACA CACATATATATACATGCATATATATTATATATATA

(2) INFORMATION FOR SEQ ID NO: 129:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 93 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBIRBP (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 129:

CCCTAAATACTACCATCTAGAAGATACTATTGTTTCCCTAAATACTACCA TCTAGAAGATACTATTGTTTGCTTTAGGTAATCATCAGATAGC

(2) INFORMATION FOR SEQ ID NO: 130:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 164 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: (A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBKCAS (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 130:

TCATAATGTAAACCACTTTGCCCAGAGCTTGGCATATATAAAAAGTGCCT CAGTAAATGTTGCACTTTATAAGCACCACAGCTAGACCAGTTTCATAGAG AGCTTTGACATACAATAGACAAGCATACTAGACACAAAGAAAAAAAACTG TATATCTCTTTCCA

(2) INFORMATION FOR SEQ ID NO: 131:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBKCAS (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 131:

ATATATATGAGTGTGTATATGTGTGTGTGTGTATATATATATATATATAT ATG

(2) INFORMATION FOR SEQ ID NO: 132:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 174 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBKCAS (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 132:

CTGATTTTTAACGGATAAAACTAAGCAGAAAAAAAACCCCAACATATAAA CCCAGGAATCCACATCACATTATTTTTACTATTTTGCTTGAATTAGTTTA GATAAAATGCACCCTTAACCTAATCCCTAGATAAATAAAATAAAAAACAG TTACAAACATGTGGTGAGAATAAA (2) INFORMATION FOR SEQ ID NO: 133:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBPRLGR (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 133: GTCTAGAATTTAGTTTTACTGCATTTACCAGA (2) INFORMATION FOR SEQ ID NO: 134:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBPRLGR (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 134: GTTTGTGTGTGTGTGTATGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 135:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBPRLGR (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 135:

CTAACTTTAGGGAGGTCATACTTGGGGAAGTGACAGTGGGTTTCAAGGG (2) INFORMATION FOR SEQ ID NO: 136:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 177 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG1 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 136:

TTTGAGTAACTGAAGTATATTGTACTAGTAGTATCAAGTCAGAGACTTGC CCTTTTTAAAGTGAACTAGGATTTAAAAATGTTAAATGAATAGAGAAGTG CAGGATTATAAGGTATATATGAATTGGGTTTTGCATAACAAAGAAAAGTA GCTGAGAAGTGAAGGAGATGGTGATTT

(2) INFORMATION FOR SEQ ID NO: 137:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG1 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 137:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 138:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG1 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 138:

TACAACTTACATTCTAGTCCACTGGCAGTAGTTAGTTGTCCCTAGTGCTC TCATGTGG

(2) INFORMATION FOR SEQ ID NO: 139:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG11 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 139:

GCATTACTGTATTCTTTTTTATGGCTCAGTAATATTCCTC (2) INFORMATION FOR SEQ ID NO: 140:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -164-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG11 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 140:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 141:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG11 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 141:

GGCCTTGATTTCCTCATCAGTAGAGTGAGATAAAGACTGTACCTAGCTCC ACTGATAAATAAATGAGTAAAGAAGATGT

(2) INFORMATION FOR SEQ ID NO: 142:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 73 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13A (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 142:

CAGCACCGTGCTGTCCATGGTACAAAACCTGACTATTCTCAGAGTTTCTT TATTCTGTGTGGAACATCTCCTT (2) INFORMATION FOR SEQ ID NO: 143:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13A (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 143:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACGTGTGTG TGTGTGTGTGTGTG

(2) INFORMATION FOR SEQ ID NO: 144:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL:_, NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13A (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 144:

AAAGAGTCGGACATGACTGAGTGACTAAGCCAGGACACGCCCACGTGCCA GCATGCCCTCACTTGCCCTAGTGCATGCCCCCGCCCTCC

(2) INFORMATION FOR SEQ ID NO: 145:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 77 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13B (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 145:

ACGTCCTCTAGATTCATCCCTGTTGTTGCAAATTGAAGGATTTCTTCTTA TGGTTGAATAATATTCCGTTATATAAA

(2) INFORMATION FOR SEQ ID NO: 146:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13B (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 146: TGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 147:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13B (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 147:

TTGTTTATGGGGTCACAAAGAGTCGGACATGACTGAGTGACTCACTTTCA CCTATAATATT -1 67-

(2) INFORMATION FOR SEQ ID NO: 148:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG3 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 148:

AGCTTACTTTGAAAATTTGACACAGGGAGTAATNANGATTTCTTTTGAAA TGACCTCAGGTTCATCAATCTCTATTCTTATACTACTCTATAAAGAATCT CTATATTCAAGTTTGGTTGGATGTTTTGTAAGTACAGAAAACTATTGGGT GGGCGGGGCAGGGGGAGGAAGGAGAGAAAGAGGAGAGGGAGAGAAGGAG

(2) INFORMATION FOR SEQ ID NO: 149:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG3 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 149: GTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 150:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -186-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG3 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 150:

GATATACCAATGAATATCAAGAAGTTTACTACAGCCAACTGTTCCATTAA GGTTGAAA

(2) INFORMATION FOR SEQ ID NO: 151:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG4B (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 151:

TTCCAGTATTCTTGCCTGGGAAATCCCATGGATAGAGGAGCCTGGTGGGC TACAGTTCATGGGGTCAGAAAGAATCAGACATGACTGAGCACACATGATG CATTAACTTGCTGCTACAAACTCTTAAGAGCAGCTTCTTTCTTTCTCATC TTTCTTCTGCTCTCCAGTCTCAACATCCTTGTTTCTTAGGAGGAAGTGA

(2) INFORMATION FOR SEQ ID NO: 152:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG4B (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 152: -139-

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 153:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 134 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG4B (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 153:

AAATGCTTGAATCTTATAGTATCCTTTATTAATATTCTGAATAATTTGAG GGTCGATAAACTTTTGGATGTGAGCGGAT...AAGCCCACTTAGATGTGA TTTGTGATGCTCTTGGAAGCTTATTGTATAAAGT

(2) INFORMATION FOR SEQ ID NO: 154:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY:- linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG7 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 154:

GTTCATTGCAGCACTATTTACAATAGCCAAGATATGGAAGTAACCTAAAT GTCCATCAACAGAAGAATGAACAAAGAAGA

(2) INFORMATION FOR SEQ ID NO: 155:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 72 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -l 9o-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG7 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 155:

TGTGGTGTGTGTGTGTATATCTATTTACACACACACACACACACACACAC ACACACACACACACACACACAC

(2) INFORMATION FOR SEQ ID NO: 156:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG7 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 156:

ACCGTAAGTTTGTTTTCAAAGTCTGTTAGTCTCTATTTTGTAAATAAGTT CCCTGTATCATTTTTTGAAGATTCCACTTATGATATGATATTTGTTTTTC TCTGTCTGATTTATTTCACTTTGTATGATAATCTCTAGGTCCATCCATCT GGCTGCAAATAACATTATATTGTTCTTTTTTATGGCTGAGTAGTATCTG

(2) INFORMATION FOR SEQ ID NO: 157:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 113 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: (B) CLONE: TGLA10 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 157:

CCAGCTACCTCTTCCTCTGAGCATTTCTTGATTCCATGTTTGGTCAAATA GGGGTTTGATTTGTCACAGTCTAAATTTATCCACTGTGGCTCTTACAAAT TATTCAAATTATA

(2) INFORMATION FOR SEQ ID NO: 158:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA10 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 158:

TGTGTGTGTGTGTGTGTGTGTATAGACATGCATGTATATGAACATATATA TATATA

(2) INFORMATION FOR SEQ ID NO: 159:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA10 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 159:

TAACACATCTTTCCTTGGAGACACAATGCAATCTGCAGTAGCATACATCC TTGTTTATTTTTACATAGTACAAATG

(2) INFORMATION FOR SEQ ID NO: 160:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 84 base pairs (B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA102 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 160:

GGTTCTTTATCACTAGCGCCACCTGGGAANCCCCCTCTCCTCCCTATACT GGTCTATATTTCTCAGTCACCAACTATATCACAC

(2) INFORMATION FOR SEQ ID NO: 161:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA102 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 161: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 162:

(i) SEQUENCE C÷HARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus 493-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA102 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 162:

GTGACTACCTACCCTGTGCCAAACATTGGCAGCTAAGATGCACTGTTTCC CTCCAAGAAGGCAGGCAAGGGGAAGGAAA

(2) INFORMATION FOR SEQ ID NO: 163:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 88 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA109 (up)

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 163:

AAAAGTTCATTGAGTAAATACTCTGTCAAGCACTTGGGATGTAGCAATCA GTAAGAAGGACTTGTTTCCTGCTCTTCTAAAGTTTGTA

(2) INFORMATION FOR SEQ ID NO: 164:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA109 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 164: TGTGGTGTGTGTGGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 165:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 78 base pairs

(B) TYPE: nucleic acid 494-

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA109 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 165:

AAAAAATCCCATGGACNGAGGAGCCTGTTGGGCTACAGCCTGTGGGGTTG CAAAGAGTCGGACATGACTGAGCAACTA

(2) INFORMATION FOR SEQ ID NO: 166:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 108 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA110 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 166:

AGAGTTGGACGTGACTGACCAACTAAGCACAGCACAGCATTTACTTATAC ACACTCACCTGCATAAATTTTAAATGGATAGTAAATAAAGTTCTGAATCC AATTCCTC

(2) INFORMATION FOR SEQ ID NO: 167:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA110 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 167:

TGTGTGTGTGTGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 168:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 135 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA110 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 168:

AGTCTTGTGGGACTGGGCCCTTTACCTGTGGCATTTAATGCTATCTCCAG GAAGACAATGTCAGAAATGAGTTGTATTTTCAGACAGCCCGCTGGTGTCA GAGAACTTCTTGTTGTTGTGGTGGTGAAACCTAGA

(2) INFORMATION FOR SEQ ID NO: 169:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA111 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 169:

ATTCCGTGGACTATATTCCATGGGGTCACAAAGAGTCAGACACAGCTGAG C

(2) INFORMATION FOR SEQ ID NO: 170:

(i) SEQUENCE CHARACTERISTICS: -t9 -

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA111 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 170: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 171:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA111 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 171:

ATACAATTCAATTATGTAAAAATTTGAAAAATGTTCTACTAGTAACTGAC ACTG

(2) INFORMATION FOR SEQ ID NO: 172:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 158 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA112 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 172:

CCTTGCTTACCTCTGGTACCTTCTACGGGGAGAAGGCAGAGGAGTTTGCA TAGCTCAAAGCTAGTGGCCTTTACCAGCAAATGTCTGTGACCGGGAGCTT TCCCTATCTCCCCCACCACTCCCCCCATTGCTAGAACCCAGGGTAGGCTG CCTGG...

(2) INFORMATION FOR SEQ ID NO: 173:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA112 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 173: GTGTGTGTGTGTGTGTGCGTGTGTATGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 174:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 137 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA112 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 174:

TTTCTTTATGGTCCAAATCTCACATCCATACATGACTACTGGAAAAACCA TAGCTTTGACTAGATGGACCTTTGTTGGCAAAGTAATGTCTCTGCTTTTT AACATGCTGTCTAGGTTGGTCATAGTTTTCTTCC...

(2) INFORMATION FOR SEQ ID NO: 175: (i) SEQUENCE CHARACTERIS ICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA116 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 175: AAAAATAGCACAGTAATAAGAGTGATGGCAGAA (2) INFORMATION FOR SEQ ID NO: 176:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA116 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 176: GTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 177:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 68 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE: (A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA116 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 177:

TTTCTGTAGCAGCTCCCTATTTTCCCCAGTTTGGAGAAGATTTGGCTGTG TACCCAGTTTAAAGTGAA

(2) INFORMATION FOR SEQ ID NO: 178:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA117 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 178:

GTTTGTAATGCTTTCTCTGCGATTATCCATTGGTTACCACAGCCAGCT (2) INFORMATION FOR SEQ ID NO: 179:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA117 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 179:

TGTGTGTGTGTGTGTGTGTGTG

(2) INFORMATION FOR SEQ ID NO: 180:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs -2oo-

(B) TYPE: nucleic acid

(C) STP.ANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA117 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 180: GATCTAATTTAAGTGTGCGTCCATGCATG (2) INFORMATION FOR SEQ ID NO: 181:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 77 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA12 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 181:

AGTGTGTGATGAAAACATTATTTGTTGCTATTTGAAATAGTTATCAAATT TGGTTCCAATAATAATATGTTTGTGCA

(2) INFORMATION FOR SEQ ID NO: 182:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -l ( -

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA12 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 182: TGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 183:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 88 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA12 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 183:

TTCCCAGAGGTTGAGGTTCTGAGGAACTTGGGGCCTGAAGAGGTTTCTGG GTGCCACACCATAGCATCTACTACATGCATGTTTGTGT

(2) INFORMATION FOR SEQ ID NO: 184:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA122 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 184:

CCATGGGGATTCTCCAGGCAAGAACACTGGAGTGGGTTGCCATGCCCTCC TCCAGGTAAATCAGC

(2) INFORMATION FOR SEQ ID NO: 185:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 41 base pairs

(B) TYPE: nucleic acid -2θ2-

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA122 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 185:

ATATATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 186:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(Vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA122 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 186:

AAACGACAACAATAACCAGAAAACAATCACATGGCAAATAAGTACATACC TATGAATAATTTT

(2) INFORMATION FOR SEQ ID NO: 187:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 69 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: (B) CLONE: TGLA123 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 187:

GATCAGGGCTCAGACTGCTACTAGACAAAGAAGAGAAGCCAAGCTTTGCT TCTGCTTCTCCACAGGCCC

(2) INFORMATION FOR SEQ ID NO: 188:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 26 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA123 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 188: GTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 189:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA123 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 189:

GCCTGCCTGCTGGTGAGGTCTGGCTCTGGGCCCTGGGCTGAGGGAGGATG AACAG

(2) INFORMATION FOR SEQ ID NO: 190:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 60 base pairs

(B) TYPE: nucleic acid

(C) STR^DEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA124 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 190:

GATCTAGGGAGTTGGGATGATGTGGAAGCAAGAGATGGAAAAAGAGGACC AGTGAATGCA

(2) INFORMATION FOR SEQ ID NO: 191:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA124 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 191: TGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 192:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STR2-J-IDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGIN.AL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA124 (down) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 192:

.AATTCTTAGTCTAGTTCAGGTAGGCTTTTATTTCTGTCTCTTCCTGTATA GGCCTTTAT

(2) INFORMATION FOR SEQ ID NO: 193:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA125 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 193:

GCTGTGTTTTCCTACAGTCCTCATACTATTTCTTTCGATTTCCCCATGAT AAACAG

(2) INFORMATION FOR SEQ ID NO: 194:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 7 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA125 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 194: AMAZING (2) INFORMATION FOR SEQ ID NO: 195:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -20 >-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA125 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 195: GAGCTGGCCTTGTTGAGACCTTCTGTGTGCATGT (2) INFORMATION FOR SEQ ID NO: 196:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA126 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 196:

TTTATATTTAGGAACTTTCCACTACTCTCTGCTAATTTAGAATGAGAGAG GCTTCTGGA

(2) INFORMATION FOR SEQ ID NO: 197:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA126 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 197: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 198:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 81 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA126 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 198:

TTGGAGTACTGTAAAGGAATTAAAGGACCTTGGCTCTATTCTCTGAATAT TCCCCACCACACCCACACCCATCTCCCCCCT

(2) INFORMATION FOR SEQ ID NO: 199:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 104 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA127 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 199:

TGCAATTGTGTGGTAGTTTGGACATTCTTTGGCATTGCTTTCTTTGGGAT TGGAATTAAAACTGACTTTTTCTAGTCCTGTGGCCACTGCTGAGTGGTTT GATG

(2) INFORMATION FOR SEQ ID NO: 200:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 35 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -2o&~

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA127 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 200: ATATATGTGTGCGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 201:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA127 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 201:

ACAGAGAAGATATAATTAACATGTATTGATTAGACCAAGACACTATTGCA AAGGACCTCCAATT

(2) INFORMATION FOR SEQ ID NO: 202:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 71 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA128 (up) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 202:

TGAAACTATAGTTGATTTACAATGTTTTTTTAGTTTTACATGAACAGCAA AGTGAGTCAGTTATGTAGACA

(2) INFORMATION FOR SEQ ID NO: 203:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA128 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID^' NO: 203: TGTGTGTGTGTCTATGTGTGTGTGTGTGTGTGTATGT (2) INFORMATION FOR SEQ ID NO: 204:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 128 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY-: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA128 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 204:

TGCACACATCAGGCCTTCTGGGAGCATGGACACATGTGTGGAGGAAGGAG GGAATTTCAAAGGCAAAGCAACTGTTTCCAACCAGAGACAATGAATTCAA ATAAATACAATAATTAATTATATCAAGA

(2) INFORMATION FOR SEQ ID NO: 205:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 88 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA13 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 205:

CTGTGTTCTCTATTGTGTTCCATTGGTATATTCCAGAGAATGTTTAAGAG CCTCTTTTTTACTTGTGCTCCATATGTATATAAAACAT

(2) INFORMATION FOR SEQ ID NO: 206:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA13 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 206:

ACACATGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATAA CATTATATATATA

(2) INFORMATION FOR SEQ ID NO: 207:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 152 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA13 (down) ~ 2.i l-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 207:

GTACCAGAAGAGACTAGAGAGGAAATGTGCAGAAGAACTATTTGAAGAAA TAATGGCTCATTTTTTTTTTTTCTGAAATAGATAAAAGACAGCAATGCAG AAATCCACAAAGCTCATCAAACATTTAATATACATATATGACTATGTGCC CC

(2) INFORMATION FOR SEQ ID NO: 208:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 101 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA130 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 208:

CCAACTGGCCAGTCATAATAAATTGACACTGATTCCTTTTTCATCTGAAA ACAATAAAATAAAATAACAATACATATAGAGGATGATACCATTTATGT..

(2) INFORMATION FOR SEQ ID NO: 209:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 26 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA130 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 209:

GTGTGTGTGTGTGTGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 210:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 41 base pairs (B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA130 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 210:

ATGGGGCCGCAAAGGGTTGGATGCACTGTGCATGTGTGCAA (2) INFORMATION FOR SEQ ID NO: 211:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 181 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM:. Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA131 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 211:

TGGTAACTCTGAATTTCAGTTGGTTTAGATTCCACATATAAGTGATATCA TACAGTATTTGTCTTTCTCTAACTTATTTCACTTAGCATAATGCCCTCAG GGTTCATCCATGTTGTCAGAAATGGAAGAACACCCATCTTTTTTCATGGC TGAGTAATATTCATGTTTTTGTATCTGTGTC

(2) INFORMATION FOR SEQ ID NO: 212:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: -2.13 -

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA131 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 212: TGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 213:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA131 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 213: GATCAATGGATAAAGAAGATGTGTACACATACGT (2) INFORMATION FOR SEQ ID NO: 214:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA132 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 214:

TTGCAAATACTGTGAAATGGTACCTTTTTAAACCCTTGGTTTCTAATTGT TTATTGCTAGTGTAA

(2) INFORMATION FOR SEQ ID NO: 215:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs -2.14-

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA132 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 215: TGTGTGTGTGTGTGTGTGTGTGTGTGTATATGTATAT (2) INFORMATION FOR SEQ ID NO: 216:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 92 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM:- Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA132 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 216:

AGTTTACCAAGGTTGCAGGATATAAGTCAATATAAATCAATCATATTTAT ATACACTTGTTGTTCAGTTGCTAAGTCATGTCTTTCTCTTTT

(2) INFORMATION FOR SEQ ID NO: 217:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 68 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -21S-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA134 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 217:

AAAACGCAAGATTCAGCGAACTTTTTCTGTAAATGAGCAGATAGTAAACA TTTGAGTCTTGGTAGGAC

(2) INFORMATION FOR SEQ ID NO: 218:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 35 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA134 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 218: GTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 219:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: .53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA134 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 219:

TCCAGGTGGCACACAGGGTCGCAAGAGTTGGACATGACTGAAGTGACTCA GTG

(2) INFORMATION FOR SEQ ID NO: 220:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid --D 6 -

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA135 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 220:

GATCCACTCACTTTTCTGAAGAATTCCAGATAGATTTCGTCTGAAATTAA ACACATATGTGAGCA

(2) INFORMATION FOR SEQ ID NO: 221:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM:^' Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA135 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 221: TGTGTGTGTGTGTGTGTGAGTG (2) INFORMATION FOR SEQ ID NO: 222:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus vii IMMEDIATE SOURCE: -017-

(B) CLONE: TGLA135 (down) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 222: AAAGAGTTGGACATGACTGAGTGACTAAA (2) INFORMATION FOR SEQ ID NO: 223:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA137 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 223:

AACTTTTCAGATTATCCTACTACTTAAGGGGGTTGACTTGTTAATCACTG ACAGCCCATTTGA

(2) INFORMATION FOR SEQ ID NO: 224:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA137 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 224: TGTGTGTGTGTGTGTGTTGTACCTGTGTG (2) INFORMATION FOR SEQ ID NO: 225:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 94 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -2-16 -

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA137 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 225:

AAACAACTGCCTGCAGGATTGGTTGTCACAGAGAAATTGTAGCTCTCCCT TAGACACACGTGAAGTCCACCTGTGCATCATTCATTGCACATAT

(2) INFORMATION FOR SEQ ID NO: 226:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 72 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA141 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 226:

ACTGACTTGCACAGACAGCTGAGAAGAGTCTAGTCCCATCATTGTGGTAG ACATTTGAACTTGGTCCTAGGA

(2) INFORMATION FOR SEQ ID NO: 227:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA141 (repeat) -2.9-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 227: GTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 228:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 83 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA1 1 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 228:

AAAGCTGGCCCAGCTGTACTTTGTTTTATCTCCATAATCTTCACTCCAAA CCCCGCTTCTAGTTGGGGCCCTCCCTCCTAAAT

(2) INFORMATION FOR SEQ ID NO: 229:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 78 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA142 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 229:

ACTTCAGTCTCTTTGCCAAGAGGGAATGAATGGAGTGTTTCTTTTCGCCC TCTATATGTTGTTTTAGCTGGATTTTAT

(2) INFORMATION FOR SEQ ID NO: 230:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -22 -

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA142 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 230:

TTGTGGCTGTAGAGTGAGTGTGTGTGTGTGTGAGTGTGTGTGTGATGT (2) INFORMATION FOR SEQ ID NO: 231:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA142 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 231:

AAAGATGTCAGGACAACAACGGAAGTATTAGGACCATGAAGAGCAGTCAT GCTGAATCAATTACTGA

(2) INFORMATION FOR SEQ ID NO: 232:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA147 (up) ^ 22.1-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 232:

TTCTCTTGAGAAGAACAGAGTGCTATGCATTTAACCAAGGATGTA (2) INFORMATION FOR SEQ ID NO: 233:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 19 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA147 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 233: TGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 234:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 70 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA1 7 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 234:

AATATTTTAAAATAGAACCATCCTGGAAAAATGCAAAATAGGAAATTTAG ACACACAAACATACCCAAGA

(2) INFORMATION FOR SEQ ID NO: 235:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) -2Z2--

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA149 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 235:

TTTTTTTAATTGAAGTATAATTGACATATATTATATTACTTCTTCAATAT CTTGTAATAACTTATAATGGAAAAAAATCTGAAAAGCAA

(2) INFORMATION FOR SEQ ID NO: 236:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA149 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 236: TATATATGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 237:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 81 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA149 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 237: CTCAATTGAAGTGCACTTGATTTACAATGTTTCAGGTATATCACAAAGTG ATTCAGTTTTATATATGTGTATGTGTTTGAG

(2) INFORMATION FOR SEQ ID NO: 238:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 198 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA15 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 238:

CCAGTCAGTAGAAGTTACTTCATGGAATGAAGGATATGTTGAAATAAGAC AGAAGTTGGTGACTGTACAACACTGTGAATGAACTAATGGCACAAAATTA TTTGCTTTAAATGGCATCTGAATATATATACATATGAATTATATTTTAAT ATATAATATTCTGTATAATGCATAATATAATCAAATGATTGATTCCAC

(2) INFORMATION FOR SEQ ID NO: 239:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA15 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 239: TGTGTGTGTGTGTGTGTGTGTGTGTGGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 240:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 94 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -22-*+-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA15 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 240:

GCATGAGAAACCACACGGACAGAGGAGCCTGGTAGGCTATGGTCCAAGGG TTCACAAAGAGTTGGACATGACTGAGCGAATAAACTACAACAGT

(2) INFORMATION FOR SEQ ID NO: 241:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 97 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA153 (up)

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 241:

CTGATGTATAGCACTGGGAGCTCAGCTAGGTTCTCTGTGATGACCTAGAA GGGTTTGGTGGGTGAGGGAGTGGGAGAAAGGCTCAAATAGGAGAGGA

(2) INFORMATION FOR SEQ ID NO: 242:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICP&L: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA153 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 242:

TATATGTATATGTATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG T

(2) INFORMATION FOR SEQ ID NO: 243:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA153 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 243:

AATGCAATTGCTTTACAGTGTTGTGTTAGTTTCTGTTGTACAACTGCATG ATATAGCAT

(2) INFORMATION FOR SEQ ID NO: 244:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA154 (up)

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 244:

TTAGCGTGGTTGAATGAAGCTCTTTGCTAAGACCAATATAGAGAATTATG TTGTCAGATACTTCAGCTTGGAATGGGGA

(2) INFORMATION FOR SEQ ID NO: 245:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA154 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 245: TGTGTGTGTGTGTGTGTATATGTGTGG (2) INFORMATION FOR SEQ ID NO: 246:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 131 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA154 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 246:

AAAAATGAAGTAGGTTCCCCAGGACCATATCAACAGAAACCTAAATTCCA ACTGGACCTGGTACATAAAGACTCCAACATTACGTGATTATGACACTGAT ATAAAAGTTTGGTTTTCTCAACTCCCTGGGC

(2) INFORMATION FOR SEQ ID NO: 247:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: - 22.-7 -

(B) CLONE: TGLA158 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 247:

GGTTTTGTCAGAAAAATGGAAAGATTTACTGGATGATGGTCTCAATTTGT AAAGTGCACTGTAGTA

(2) INFORMATION FOR SEQ ID NO: 248:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 16 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA158 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 248: TGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 249:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA158 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 249:

TTTTTCATACTCACACCAAGTTCACTTTTAACAGGTATCTTTTTTTCTT (2) INFORMATION FOR SEQ ID NO: 250:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 99 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA159 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 250:

AGAGACATACCTGTGGCATCCAGGGAACAAATTACAAACCATATTCTCAC CATTCTGTCTTTCCTACTCCTCCTCTCTTGGGTCTCTTGCATTATTATC

(2) INFORMATION FOR SEQ ID NO: 251:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA159 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 251:

TGTGAGTGTGTGTGTGTGTGTGCGTGTGCAAGTGCATGTGTGTG (2) INFORMATION FOR SEQ ID NO: 252:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 86 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA159 (down) - 2-2^ -

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 252:

TTTTTATTTCGAATCTCTTGAGTACAGACATCTTTGCCATTCTTCCTCAG TTCTTACTTTTATGCAAAAGCAGATTCACATAAGTG

(2) INFORMATION FOR SEQ ID NO: 253:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 88 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA160 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 253:

AAAATATATTGTCTTAATAGAATACGTTGTTTTGTTTTTAAAGCTCTTTG AAGACATGAGAAGATTCCCACTTTCCACACCTGGGTCG

(2) INFORMATION FOR SEQ ID NO: 254:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 16 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA160 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 254: GTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 255:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA160 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 255:

TTTCAGCAAAAGTGTCTGTGTTATGCATCATGAAGGTGGAGTGTAAGGAA ATTCCAAAAATATTCCCCCGGCCCCATAGA

(2) INFORMATION FOR SEQ ID NO: 256:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA162 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 256:

GGTGCCGTCTATGGGGTCGCACAGAGTTGAACACGACTGAAGCGACTTA (2) INFORMATION FOR SEQ ID NO: 257:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 15 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA162 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 257: -23. -

GCAGCAGCAGCAGCA (2) INFORMATION FOR SEQ ID NO: 258:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA162 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 258: GATCAGTGGTTCTCAAAGTGCCTTCACAGCATCACC (2) INFORMATION FOR SEQ ID NO: 259:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA164 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 259:

TTACCAGGTAATTAACTTGATGGAACTAAAACTAAAACTGTCTT (2) INFORMATION FOR SEQ ID NO: 260:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - 22> -

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA164 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 260:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTGTGTGTGTG TGTATGTG

(2) INFORMATION FOR SEQ ID NO: 261:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA164 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 261:

CCCATGGATAGAGGAGCCTGGCAGGCTACGGTCTATAGGGTCACACAGAG TCGGACATGACTGAAGCAACTTAGCATGTG

(2) INFORMATION FOR SEQ ID NO: 262:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA17 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 262:

TTTAACTTCTATGCAGAGTACATCATGAGAAATGCTGGACTGGATGAAGC ACA (2) INFORMATION FOR SEQ ID NO: 263:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA17 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 263:

TGTATATGTATGTGTGTGTGTGTCTGTGATGGTGTGTGTGTTTGTGTGTG TGT

(2) INFORMATION FOR SEQ ID NO: 264:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA17 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 264:

GGTTGCAAAGAACTGGACATAACTGAGTGATTGAAATGAACTGATATCTT GTTGCAGACTTCTT

(2) INFORMATION FOR SEQ ID NO: 265:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA170 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 265:

CTATGCTGTACAGTAGGTCCTTGTTGATTATGTTACACATAGTATGCA (2) INFORMATION FOR SEQ ID NO: 266:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA170 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 266: TGTGTGTGTGCGGCGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 267:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA170 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 267:

TGTGTGAAAACAATGTCGCTACTAGTAAGGACCTGCTGTATAGCACAGGG (2) INFORMATION FOR SEQ ID NO: 268:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA171 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 268:

TCTGTCTCCAACAATCCCAACTAGTGAGTGTAGCAAGAACCCAATTACCC CCAGGCCCTTTTAGTTA

(2) INFORMATION FOR SEQ ID NO: 269:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 15 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA171 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 269: GTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 270:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE : NO

(vi) ORIGINAL SOURCE :

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA171 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 270:

GAGGAGCCTGATGGGGAGCCATGGGGTTGCAAAGAGTTGGACCTGAGTGA CTGAACACG

(2) INFORMATION FOR SEQ ID NO: 271:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 71 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA172 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 271:

CAGATTTCGCAAGCAACAAGAGGTCACCTAGTTGAATTAGAACTTTAGAT TAACAGTGGGGTATGAGTGTT

(2) INFORMATION FOR SEQ ID NO: 272:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA172 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 272: TGAGTGTGAGTGTGTGTGTGTGTGTGAGTGTGAGTGTG (2) INFORMATION FOR SEQ ID NO: 273:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA172 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 273:

CATGGACAGAGGAGCCTGGCAGGCTACAGTCCTTGGGGTCTCAAAGAGTC AGACACTACTGAGCAT

(2) INFORMATION FOR SEQ ID NO: 274:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA175 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 274:

CCCATGGGTTTGCACAGGTTCATGAGACAGTCCGTGAATGGCTGGGCTTG TATATGGTTGTT

(2) INFORMATION FOR SEQ ID NO: 275:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -232- (iv) .ANTI-SENSE : NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA175 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 275:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 276:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA175 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 276:

GGGATATCAAAGCCAGAAAAAGGCAGGGGTATACCCCAGTGTAGAGACTG TCTACT

(2) INFORMATION FOR SEQ ID NO: 277:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 68 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA176 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 277:

TGAGCAGGGTTGTTCTGGGTGAGAAATGGGTAGTAGGAATAC7CCCAGGA GGAAGTGGTGTGAGCAAT (2) INFORMATION FOR SEQ ID NO: 278:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA176 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 278: TGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 279:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA176 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 279:

TCCAGGCACCTATGCTTTAAGAACTGCTCTCAAGGCACAAGCACACAGTC AGGG

(2) INFORMATION FOR SEQ ID NO: 280:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO -2H 0-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA179 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 280:

TACTGATTCTAGGTTAAACTTTAATCAGCACACAGCTTCCCAGTTAGCTG TTT

(2) INFORMATION FOR SEQ ID NO: 281:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA179 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 281: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 282:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 69 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA179 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 282:

CCTCAGGGCAGTTTCCAAAAAAATGCTAAGCTGCATATGTGCTAGAAGTT TGGTCAACCCACACCCTCC -2m-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA182 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 283:

TTTGATGAGCGACGGCACGACAGCCACAGCAAGTGGGATGGATACACACA AACGTTGGTTTCTTTTGGACTATGAGCCCACCTCTGTTC

(2) INFORMATION FOR SEQ ID NO: 284:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA182 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 284:

GTGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA GAGAGAGAGAGA

(2) INFORMATION FOR SEQ ID NO: 285:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 118 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA182 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 285:

GAAACAGTCCACGTCGTCCTCCAACTCATTGGACCATCACGACTGAAATG AAGGAAAATATGTTCGTTCGAGAATGTCTTCACTCCTCAGTGCTTCTTGC TTTAGAACCACCAAGGCA

(2) INFORMATION FOR SEQ ID NO: 286:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 85 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA188 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 286:

CATGTGACTGTTCCTCATCTGTGTATCCTTCATTGAA...AATATCTATT CAGGTCATCTGCCCTATTTTTTAATTCCAAACCTA

(2) INFORMATION FOR SEQ ID NO: 287:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 17 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA188 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 287: TGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 288:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 68 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA188 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 288:

GATCTTTGCAAATGGTATTTCTGATAAGGGGTTAATATCAAAAATATATA AATAACTCATACAACCCA

(2) INFORMATION FOR SEQ ID NO: 289:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA189 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 289:

TTTGGGAAACTAAATGCCTCCTCCTAATCCTGAGGATGAATTTGTAGTTA AGGTGCTCACTATTTCTGTGGGAAAA

(2) INFORMATION FOR SEQ ID NO: 290:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA189 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 290: GTGTGTGTGAGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 291:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA189 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 291: AACTGCCGAAAACATTCTGTGAGCATGCTTTCACAA (2) INFORMATION FOR SEQ ID NO: 292:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 77 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA2 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 292:

ATGACCATGATTACGCCAAGCTTGGGCTGCAGGTCGACTCTAGAGGATCC TGCTACTGTCAGGACTGAACACTGCTC -2HS-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA2 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 293: TGTGTGTGTGCGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 294:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 141 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA2 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 294:

TGCTTGAGGAGTCAAAATGAGCTATGCTCCAGTAAAAGGGGAGCTCTCAA ACAGCTTGCCAGTACAGATTTCGACAGCAGAGGCATTTTGCTGGCAGTTG GGGAATATACTGGCATTCTCAAGAAACAAGAGCTTTTAGGG

(2) INFORMATION FOR SEQ ID NO: 295:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 81 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - ■ 2 -K -

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA20 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 295:

TTTGTAGCAAAGTCAGTTGTAGTTTATTTATTCCTTGATTATGTATACTT AATGTCAAACCCAGTTAAAATAGCAAGAGTT

(2) INFORMATION FOR SEQ ID NO: 296:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 60 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA20 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 296:

TGTGTGTGTGTGTGTGTGTGTGTGTATATATATACATATATATATATATA TATATATATA

(2) INFORMATION FOR SEQ ID NO: 297:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA20 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 297: GATCTGTTTGTGAAGTAACATTGTAAGTATTGGGGAAAA (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 95 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA203 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 298:

TTGGACTCTCAAGGCAATTGGGACTGAAGATGCCCTGGGGTCCCCACACA AGCTCCTATCCTAATTACACATGAGGAACCCCAGGTGTTAATGAC

(2) INFORMATION FOR SEQ ID NO: 299:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA203 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 299:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGTGGTGGTGGTGGCAA TCAGTCAATTTTTTTTTTTTTTTTTT

(2) INFORMATION FOR SEQ ID NO: 300:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 110 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA203 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 300:

GCAGCTTAAAGAATGACTGAAATCATATCATTTGGTTCCATCCAGACAGC CCCATTATGGTAGTGGGTGAAGAGGAAAGCAGACTAGGACCTTCAGTGAG GGCAGAGAAA

(2) INFORMATION FOR SEQ ID NO: 301:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 93 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA206 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 301:

TTGTACAGTTAAGCAAACCATCAACAAAACAAAAANNNNNGCCTACTGAA TGGGAGAAGATATTTGCAAGCGTTACGCTCGAAAGGCTTAAGA

(2) INFORMATION FOR SEQ ID NO: 302:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA206 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 302:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGAGAGAGAGAGAGAGA (2) INFORMATION FOR SEQ ID NO: 303:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 131 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA206 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 303:

TTGATAGCCATTCTGAGTGGTGTGAGGGGATACGGCATTGGGATTTTGAC TTCCATTTTCCTGATAATTAGTAATGTCCAGCCCATTTACATGTGCCTAC AGACCACTGGCATGTGGTAGTCATACCTTCA

(2) INFORMATION FOR SEQ ID NO: 304:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 164 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE:. DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA208 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 304:

TGGTGTGCTGCAGTCCATGTTACACAGAGAGTCAGACAATACTGAGCAAC TGAATTGAACTTTGCCATAGGGAGAATGCTTTACAAGTTCTTCACATGTA TCAAAATAAAACAGAAAAAGATGTTTCTTTAACATGGAAGGATAAGCAGG GCAAGCAACAACTC

(2) INFORMATION FOR SEQ ID NO: 305:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA ( enomic) - 25C-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA208 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 305:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 306:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 159 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA208 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 306:

CCACTGACTTGGCTTGGCTAAACTTTAGCTAAGCTTCTCTCCTCTGAACT TCAGCTTTCCCCTAAGCTTGAGCAAGCACTAAGAGCCAGGCTTTTCTGTC TCCCTTAATAGCTCATTTTGGGAATCAACTCACTACAGAGAAAAATACTT TCTGTTAAA

(2) INFORMATION FOR SEQ ID NO: 307:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 125 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA210 (up) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 307:

TTTCACAGTTGTCTAAATAAGAGAGTTATAATCACCCCACCCCCAGGTCA TGGTCTAGTGCTCTTCTTCCAGAAAAATCCAATCTAAGCATTTGGGTGAA GGGGGTCTGGCTGAAGACAACAGGA

(2) INFORMATION FOR SEQ ID NO: 308:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA210 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 308: TGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 309:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 133 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA210 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 309:

TCTAGAGGATTCCCTGGAGAAGAGAATGGCAACCCACTCCAGTATTCTTG CCTGGGAAATCCCATGGACAGAGGAGCCTGGTGGGTTATAGTCCATGAGG TTGCAAAGAGTCAGACAGGACTGAATGACTAAT

(2) INFORMATION FOR SEQ ID NO: 310:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 183 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) røTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA213 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 310:

GTGCTCTATCACAGCAAGTAAGGAATCACAGTCAAGTCACTAGAGGGCAG AAGGACCTTGATAACTAGGCAGAGCTTTGCTCCATCTTAGAGTTCCTTAG TGACCCTTGCTGAAGCAGAAATCTGTTGGAGAAAGGCTACTTTAGGCCTG TTGGTGATAATGTGTGAATAGGAGCTCTGGTTT

(2) INFORMATION FOR SEQ ID NO: 311:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA213 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 311: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 312:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 174 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA213 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 312:

TGGAGAATCCCATGGAAAAAGGAGCCTGATGGGCTACAGTCTATGGGGTC GTAAAGAGTCAGACACGACCGAAGCGACTTAGCACACACTGAGTATTTAT CCGTTTAGAAAAATCATCACACTAAAAATTGTGCCCACAGGAGAGTTTGC TCATCCTTCTACTGATTCAAA...

(2) INFORMATION FOR SEQ ID NO: 313:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 197 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA214 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 313:

TTCCCTTAAAAAAGAGAGCTTTTTGAAGGTTTTGAGAGAATTGAACCTAT TTTCNNCCTTAGACTGGAATTACAATGTGAATGTATGTGCATGTGTGATG CTTAGTGGCTCAGTTCGTGTGCCCAACTCTTTGTAACCCTATGGACTACA GCCTGCCAGGCTTCTCTGTCCATGAAATGTTCCAGGCAAGAATACTG

(2) INFORMATION FOR SEQ ID NO: 314:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA214 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 314: GTGTGTGTGTGTGTGTGTGTGT O: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA214 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 315:

TTCTTGGGGCTTCCCAGGTAGCTCAAATGGTAAAGAATCAGCAAAGAGTC TA

(2) INFORMATION FOR SEQ ID NO: 316:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 88 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

( ii) IMMEDIATE SOURCE:

(B) CLONE: TGLA215 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 316:

TTCATCCAGTGTTAAAAAAGGAAAAAGGAACCGTCATTTGTTTAGCATCA GCCACGTGCCAGGCTAGGTGATGCACTTTATACACTTG

(2) INFORMATION FOR SEQ ID NO: 317:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA215 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 317:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGT

(2) INFORMATION FOR SEQ ID NO: 318:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 73 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA215 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 318:

ATGGGCAGAGGAACCTGGTGGGCTACAGTCCATGGGGCTGCAAAGAGTCA TACATAACTGAGTGACTGAGCAT

(2) INFORMATION FOR SEQ ID NO: 319:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 100 base pairs

(B) TYPE: nucleic acid

(C) STPΛNDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA22 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 319:

TCAGTGAACTCAGGAGAGGTAAGCAAAAGAGATTCAAGCAGCTGAGAATC TTGTCTTAAGCTTCAATTGCAAGTAAAGGTTTCTTGACTCAGGATATGTA (2) INFORMATION FOR SEQ ID NO: 320:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA22 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 320: TGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 321:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA22 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 321:

GTGAGCTGCAGTTTATGGGGTCCCAAAGATTTGGACACAACTGAGCCACT AA

(2) INFORMATION FOR SEQ ID NO: 322:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA222 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 322: VECTOR-GATCACTCTCTTAACA (2) INFORMATION FOR SEQ ID NO: 323:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA222 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 323: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 324:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 118 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA222 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 324:

TTGAAGAAGGAAATGGCAACCCACTCCAATGTTCTTGCCTGGAGAATCCC ATGGATGGAGGGGCCTGGTAGACTACAGTCTATGGGGTTTCAAAGAGTTG GACACAACTAAGCAACTA

(2) INFORMATION FOR SE ID NO: 325: -256-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 150 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA226 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 325:

CTCAGAAAGAACTTCAGATTACACTTTGGGGAAACAGGAAAGCACTGGAG GACAGTTGGACCTGACATTTTAACAAAGGTCTTGGCTCCTGAGTGGAATC CAGATAAGATGTATCAAAAAGTTTGTAACGCTTTTATTTTTTTAAAGTTT

(2) INFORMATION FOR SEQ ID NO: 326:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA226 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 326: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 327:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA226 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 327:

AAAACCAAACATGAAAAGAAGCAATATCGTAACAAATTCAATAAAGACTT TAAAAATGGTCCAT

(2) INFORMATION FOR SEQ ID NO: 328:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA227 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 328: VECTOR-GAATTCCAAATCTGTTAATTTGCT (2) INFORMATION FOR SEQ ID NO: 329:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA227 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 329: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 330: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 87 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA227 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 330:

VECTOR-GAATTCAAAATAAATACTTGAAGGAAACTCAGTCAGCTCCAAG AGAACACAGACAGAAACTCAATGAAAGCAGGAAACAT

(2) INFORMATION FOR SEQ ID NO: 331:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 92 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA23 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 331:

AAGGGGTGCTGTGGTACATCAGGGCAATAGTCAGAGTCCAGGACCATTCA TGCAAACTGAGACACAAGCTTTCAACCACCACCTATATTAAC

(2) INFORMATION FOR SEQ ID NO: 332:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - -1(o\ -

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA23 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 332: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 333:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA23 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 333:

CCTGGAAAACTCATCTTTAATCATTTGCCCCAGTTGATTTATTAAAAACA AATGCATTAAATA

(2) INFORMATION FOR SEQ ID NO: 334:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA231 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 334:

GGCGAGCTCGAATTCTCCATTTCCCTTTGGTTTGTAAAGACAGT (2) INFORMATION FOR SEQ ID NO: 335: (A) LENGTH: 26 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA231 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 335: TGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 336:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 119 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA231 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 336:

VECTOR-GAATTCAAATTCTCGCAGCACATTTTAATCATCTACCTGCTGG CAATTAACTAACATTAAGACTGCTGCAAAGAGTTGGACAGAACTGAGCAA CTGAGCACACGCGTGCGTG

(2) INFORMATION FOR SEQ ID NO: 337:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO - 2fc3-

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA245 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 337:

TTTTTGCATCTATGTTCATCAGTGATATTGGCCTGTAGTTTTCTT (2) INFORMATION FOR SEQ ID NO: 338:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA245 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 338:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 339:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 107 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA245 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 339:

GCTAATGCTTATCCTTCTAAAACTCTTTCAAAAAAATTGCAGGTGAAAGA ACACTTCAAAACTCATTCTATAAGGCCACCATCATCCCAATACCAAAACC AGACAAA

(2) INFORMATION FOR SEQ ID NO: 340: - 2<i>4-

(A) LENGTH: 70 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA25 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 340:

AGGGTGCAAAGAGTTGGACACGACTGAGCAAGTGAACTGAACTGATTGTG TGTGTATAGCTCACCTATAT

(2) INFORMATION FOR SEQ ID NO: 341:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 26 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA25 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 341: TGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 342:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: - 2G>5-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA25 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 342:

AATATTTCTTTATGAACTGGTAAATAAACAGAAGGTGAGACCCATG

(2) INFORMATION FOR SEQ ID NO: 343:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA254 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 343: TTTATGGCTGAGTAATAATCCG (2) INFORMATION FOR SEQ ID NO: 344:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA254 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 344:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 345:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 178 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single -2 - ( -

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA254 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 345:

AATCCATCATAACTGTACAAGACTCATTTACTATGAGGCATATATCTTCA TAAAGTAACCAAAATTGAAAAAGGCACATGTATGACAATGTTCTATGCAG CTCTATTTACAATAGCCAGACATGGAAGCAACCTAGATGTCCATCAACAG ATGAACAGATAAAGAAGCTGTGAGATAT

(2) INFORMATION FOR SEQ ID NO: 346:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA255 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 346:

CAGTGTAGCTCTCTGGGCCCAGACAGAGGGGTAAGGCTGTGTGCATGTCG GG

(2) INFORMATION FOR SEQ ID NO: 347:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA255 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 347:

GTGTGTGTGTGTGTGTGTCTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 348:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 82 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA255 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 348:

ATGTGCTGCAAGGCGATTAAGTTGGGTAACGCCAGGGTTTTCCCAGTCAC GACGTTGTAAAACGACGGCCAGTGAATTCCTA

(2) INFORMATION FOR SEQ ID NO: 349:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 90 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA257 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 349:

AAAAATCACAGGGCTGCTGGAAACCACCTGTGATCTCTCTCCACTTTTCC CCTATCATTCACATAACTCTTCTCATATAGCCCAGAAATA

(2) INFORMATION FOR SEQ ID NO: 350:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs -2&8-

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA257 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 350: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 351:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA257 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 351:

ACTACAGTCCATGGGGTTGCAAAGAGTCAGACACGACTGACTA (2) INFORMATION FOR SEQ ID NO: 352:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 167 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -2k9-

(B) CLONE: TGLA26 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 352:

TTTCTGAAGGTGTTATTAAGGTCGAGGACACCATTAAGCTCCATTTAATA AAGGTTAGACTTTAACCCACCAATGTTCAGTTACTCTCTTCAGCAGTAGG CTAATGACTGCTATTGGAGCGGGAGAAGAAGGAAGGCCCAGCCATCTACT TTTCTGATATGTTGTCG

(2) INFORMATION FOR SEQ ID NO: 353:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA26 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 353:

TTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGT GTGTGTGCGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 354:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA26 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 354:

GATCTGCCTCCAGATTTTGTTTATCCCCTCAGCCACATGACAGGTTTAGA A

(2) INFORMATION FOR SEQ ID NO: 355:

(i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRi-iNDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA260 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 355:

GTGTTGTGTGTTCTGGCTCTGAGACCTCTCCCTGACCCATCGATTTTTCC CGTGTAGGATGGATTATTGACCTGTTCTGATTCAGTCTA

(2) INFORMATION FOR SEQ ID NO: 356:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 98 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA260 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 356:

TTTTTCCTTTTTTTTTTTTTTTGATGGGGTGGGCCTCTGTTAATTTGGTG ATTCCAAATAAATTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 357:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 122 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO -27t-

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA260 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 357:

CTATTCCTTGCCCCAACAACTCATTTCTAAATCTATCGGCCTATTGTGCA GTGAGCAGTAGGAGCTTGGACTGGTAGTGAATGTGAATGTGTTACTTTTT TTCAGTCATATCTGACTCTGCA

(2) INFORMATION FOR SEQ ID NO: 358:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 147 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA261 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 358:

CCCTATCTTGCTGAAGTCCTTCAAATCTTTGCTCAAATCTCATTCTCTCC AGAAGGCCTAACCTTACCACTTCCACCCTCAACACAAGCATAAAAACTGA CTGTCCTGATGCTTTTAACACTGTCCTATTTCTATGGCCTTATCTTC

(2) INFORMATION FOR SEQ ID NO: 359:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA261 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 359:

TTATATATATATATATATATATATATATATATATATATAA -27Z-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 135 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA261 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 360:

AATACATCTCAGACTGAGCTATTTGATTAATGCATTCACTTCATTCATCC AACTTATATTAGGCACAATGTCCTTGGG...TTTCTAGATGTACTAACTC TAAGTGAGTAGAGAGAATTAACAAAGCTTAGTAAG

(2) INFORMATION FOR SEQ ID NO: 361:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA263 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 361:

CCCGGCGAGCTCGAATTCCTGTTTGGAGCAGAAGCAGGAAAGCAAGTGCT GGATACTATCTGAGCAAATACAGAGAAAA

(2) INFORMATION FOR SEQ ID NO: 362:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA263 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 362:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGGGGGTGTGTGTGTGTG TCTGTGTG

(2) INFORMATION FOR SEQ ID NO: 363:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 41 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA263 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 363:

GCCCTCACCAATATTTAAAGCATCCTCACCTATATATGCCT (2) INFORMATION FOR SEQ ID NO: 364:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA264 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 364:

ACTGGGCTTTTCTCTCAAACCCCAACCGTAAGCCCAGTCTGGCTGAGTGT GAGCAA (2) INFORMATION FOR SEQ ID NO: 365:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA264 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 365: GTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 366:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA264 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 366:

TTCCCAGTCACGACGTGTAAAACGACGGCCAGTGAATTCAGCAGTTATCC

TTCCTTCCCCCAGGCT

(2) INFORMATION FOR SEQ ID NO: 367:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - 2-7S-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA268 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 367: CCCGGGCGAGCTCGAATTCTATGCT (2) INFORMATION FOR SEQ ID NO: 368:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA268 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 368:

TGTGTGTGTATTGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTG TGTGTG

(2) INFORMATION FOR SEQ ID NO: 369:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA268 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 369:

TGGAATAAAACATAGATGACGGAGTTTTCCTGATCCTTCCTCTAAACACA TTCT _27 a ^■ -

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA27 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 370:

CTCATGCTGCACAACTAGGATTGAACTATCTCTTGGTATATCTCATGCTA ATC

(2) INFORMATION FOR SEQ ID NO: 371:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA27 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 371: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 372:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 69 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA27 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 372:

ATCTCATGGACAGAGGAGCCTCTGCAGGCTGCAGTCCACGGGGTCGCAAA GAGTCGGACACAACTGAGC

(2) INFORMATION FOR SEQ ID NO: 373:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA272 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 373: CTGGCGGTTAGAGGCTTGCACGCTGTAAA (2) INFORMATION FOR SEQ ID NO: 374:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA272 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 374:

TGTGTGTGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTG

(2) INFORMATION FOR SEQ ID NO: 375: -27S-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA272 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 375: GATCAAAGCATGGAGGCCAGAGAGAGAGTGTGTGGG (2) INFORMATION FOR SEQ ID NO: 376:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA28 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 376:

TCATTTTCTTCCTGCTTCTGTAGGTTCTTAGACTTAGTAAGTAGCTTTTC T.AAC

(2) INFORMATION FOR SEQ ID NO: 377:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA28 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 377: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 378:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 93 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA28 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 378:

AGACAGTGGGAGTGGGAGTGTCTCTGAAGATGTTTGGCCTTTAGTTGATA TGTCAGAGCTGGAATCAGACTCAGGTATCCTATCTAGATTAAA

(2) INFORMATION FOR SEQ ID NO: 379:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 83 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA3 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 379:

CATTTAGTCAGAGTAAAACAGTGATTTTTATACTTTTCTTTATAAATGTA TTTTTGAAGGCATTAAACTTAGAGAATCTACTT

(2) INFORMATION FOR SEQ ID NO: 380: RI TI -2& -

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STR.ANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA3 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 380: TATATATATATGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 381:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA3 (down)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 381:

ACTGTGTATTTTATTCTATAAATAAAATTTGTATAGAGGTTTACATATAC AGAATACAGAATAAAA

(2) INFORMATION FOR SEQ ID NO: 382:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: -2BI-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA301 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 382:

AACTCTAGAGAAAAGCAGAATTTCAAAATCAAATGAATGGATGAAGAAGG

(2) INFORMATION FOR SEQ ID NO: 383:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA301 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 383: TGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 384:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA301 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 384: TGCAGATGGTGTTATTTCATTCTCTTTTATGGCTGTT (2) INFORMATION FOR SEQ ID NO: 385:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 145 base pairs

(B) TYPE: nucleic acid ^' i -262-

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA303 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 385:

GPAATTCCCTGCAGGTTATTAGACCAGTTCTTTCCCAGTATAGATAACAGT GGCTTTTTCCACCACTTATTTTTAGGGCCTGCCTTTTTTTTTTCATATAG TTATAATCATAAGTCAAAGTAACAGTTTAGATGTCCAGTTTGCTC

(2) INFORMATION FOR SEQ ID NO: 386:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA303 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 386: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 387:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA303 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 387:

CCTCAGTAATGGTTTTGTTTTAAAACACTTTGTTTATCCTTAAAATTAAA GCGTTTGAAAGAAAGAAAATGATGTAATTTGTAAAGTGTGGCCATTAATA CAAGTGAACTTACAGATCTGGACATACAAAAGTATTACCTCAAGAGATGG ACCCACTTGTGTGCCAGACCCAGGAATCCTATAGAGGTCATACAGGAGG

(2) INFORMATION FOR SEQ ID NO: 388:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA304 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 388:

TTTTTAAGATGTCAATTGTTGATCTGTCAACCTTTCAATTGATTC (2) INFORMATION FOR SEQ ID NO: 389:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA304 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 389: TGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 390:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs (C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA304 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 390:

GATACCTAGGTGTAGAACTGAGGAGGGTCATTTATTTCTTTTA (2) INFORMATION FOR SEQ ID NO: 391:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA306 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 391:

GTTGAGAAATAACATTAATATCCATGGAACATTCAAAGATAAGACTGATG ATCAAGTACAGCAGGCTGAGTTACACTGAATTTAAAATATACACAATCAT GTGTTAGTAAAGGCATGTCCCATATAATATTTTTATTTGCTAAATCTGGC CACCTTGCTCAAGAAACATTAGCATTTAATGTCATTATTTTCTAGAAGA

(2) INFORMATION FOR SEQ ID NO: 392:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO vi ORIGINAL SOURCE: -1 ,5 c--

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA306 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 392:

TGTGGATGTGTGTGTGTGTGTG

(2) INFORMATION FOR SEQ ID NO: 393:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 160 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA306 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 393:

TTGTGTTGATAGGGGTTTTTAATGAGTCTTGCTAGAAATGTATCAGTTAC CTTCTCAGAGAGCCCGGCTTTGGCATCATGTGTTTCACTCTGTCACTTTC TGTTTTCAGTTTCACTGGTTTCTGTCGTCACCTTCATTATTCCTTTCCTT CTTCTTT...

(2) INFORMATION FOR SEQ ID NO: 394:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 141 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA307 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 394:

GAATTCCCTTCAGTCCCTCATCTTTGCATTCTCATTTACCAAGAGGTCCG TGACTCAGGTCCAGTGCAATCCATGTGTCATACAAGACAGGCAAGCAGAC AAGGAAAGGTTACCATCCTGGACTTCCAAAG..GTTTGA... - 2βώ-

(i) SEQUENCE CH.MIACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA307 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 395: TGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 396:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 148 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA307 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 396:

AGGGCATGGATGGTCCTGGGAGTCGGTGGGATGTTATACGTTTGTCCAGA GTCAACCTTGCCTGCCTCCATCTGATTTAGTTAGGACTAGAAGGAGGCAG TCTGGGTAAATTTGCCTGGATGAATCCTGAACAGGCAAGGATCCCTAA

(2) INFORMATION FOR SEQ ID NO: 397:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 69 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - 2 £7-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA309 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 397:

ATTCAGTAGTCATATGACCTTTGTCCTTTGTATTCTGTGAAAGACATTCT TTGTAGATAGCATGATAGG

(2) INFORMATION FOR SEQ ID NO: 398:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA309 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 398: GTGTGTGTGAGTGTGTGTGTGTGTGTGTGTGTGTTGTG (2) INFORMATION FOR SEQ ID NO: 399:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 195 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA309 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 399:

CATCAAAATGCTTACTAGCCCATCACTGAAAACACAATTTCGTCTGCCCA TCCAAACACCATTTTTTTCTAAACCTAGGAGGTCCATTTCAATATTATGA ATATGACATAATTGTTCTGCCAGCATTACAGATTTCATACAGCCGAGTGG - &S -

(2) INFORMATION FOR SEQ ID NO: 400:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA31 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 400:

CACCCATTTTGCCCAGAGCCTTCCTCTCCCACGTCTGCACATG (2) INFORMATION FOR SEQ ID NO: 401:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA31 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 401: CCCCCCCCCCCCCCCCGCCCCCC (2) INFORMATION FOR SEQ ID NO: 402:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -2&9-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA31 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 402:

GGGTCACACAGGAGACAGAAGAATAAGCAGTGCCTGTGCAGGGCGGTGAC CAGCAGCCAGGAGCC

(2) INFORMATION FOR SEQ ID NO: 403:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 75 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA310 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 403:

TTGTTATTTCAGATCTGCCTCTATCAACCTTTTTTCTAGTTCAAGTTAAA TTTTTCT.AATCCTTTGCACATTTGA

(2) INFORMATION FOR SEQ ID NO: 404:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA310 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 404: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 92 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA310 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 405:

TGCAAGGCGATTAAGTTGGGTAACGCCAGGGTTTTCCCAGTCACGACGTT GTAAAACGACGGCCAGTGAATTCACAAAATCTAGCACACCAA

(2) INFORMATION FOR SEQ ID NO: 406:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA311 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 406:

TTGTTGCAAATGGCAAAATTTTGTTCTTTTTTATGGCTGAATAGTATTCT A

(2) INFORMATION FOR SEQ ID NO: 407:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 16 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA311 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 407: GTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 408:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA311 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 408:

CAATGTTCATAGCAGTATTATTACAATTGCCAAGATACAGAAGCAACCTA AGTGTCTATCAATGGATGATTAAATAAAAAGGATATGAT

(2) INFORMATION FOR SEQ ID NO: 409:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA318 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 409: AGCTCTTGACCTGTCTCGGCGGCAGGG (2) INFORMATION FOR SEQ ID NO: 410: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA318 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 410: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 411:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 77 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA318 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 411:

TTAGGATATATCAGATGAGTAAGAATGCATTTACCCTTCACTATGTCTCC ATAGAAAGTTGCTTTGGGTTTGGAGGT

(2) INFORMATION FOR SEQ ID NO: 412:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO -2.93-

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA322 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 412:

GGGACCTACATCTTCTGATGCTCTTTTCCTGTTCCCTCATGCCACCTCTT GTCTGAAAGAGCAGTGTCATACAGGG

(2) INFORMATION FOR SEQ ID NO: 413:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA322 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 413: GTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 414:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 130 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA322 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 414:

CTTTTGATGTAAAAATGTTCTGGAACTAGTTGGAGGTGACGGTGGCACAG ACTTATAAATGTACTTGTAAATGCCAATGAATCATTCACTTTAACATGG-: TTAAATGACTATTTTATGTGGTATTTTAAT

(2) INFORMATION FOR SEQ ID NO: 415: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA323 (up)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 415:

GCCAGGTTTCCCAGTCACGACGTTGTAAAACGACGGCCAGTGGTGTGCGT TTGTAAGTT

(2) INFORMATION FOR SEQ ID NO: 416:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA323 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 416: TGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 417:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 96 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO -2^5-

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA323 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 417:

AGCTCTTTGTAAGATTCAGGTCACTACAGAAAGAAACACTTNCTGTCAAA CTACTCCATCATGCTGTCTGTTCATCCAGCCCCACCTTTTTCCCAT

(2) INFORMATION FOR SEQ ID NO: 418:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA325 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 418:

CCAACACTGTGGGGCACTTTACTCTCTGAACAAATCTATAGTATTGGGGA TT

(2) INFORMATION FOR SEQ ID NO: 419:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA325 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 419:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 420: (i) SE UENCE CHARACTERISTICS: (A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STPΛNDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA325 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 420: AGCTGACAGTCTATTTCCAGAAGGTAAA (2) INFORMATION FOR SEQ ID NO: 421:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA327 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 421:

CCAGTGATCTGAAGGCTAAATAACTTCTCTATCTTGCCTTTAATAGTCTC ACTGTGATACATAGGAT

(2) INFORMATION FOR SEQ ID NO: 422:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA327 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 422:

TGTGTGTGTGTGTGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 423:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 103 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA327 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 423:

CCTGCTAATGCAGGAAGAGGTAAGAGACATGGGTTCGATCCCTGGGTTGG GAAGNNNCCCCTGGAGGACGGCACAAAGACTCAGACATGACTGAAGAGAC TTA

(2) INFORMATION FOR SEQ ID NO: 424:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 146 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA328 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 424:

GAATTCCCTGCTTCAAATAAATCTTGTTTAAGGCAAATGGAAGGTAAGAG AAAGGGCAGGAGGAGAGTAAAAGAAAGGCTGATATTGTAGCATCCTACCA ATCTTTGTTTCTAAATTGCAGCAGCCTTGAAAGAGAACATTAA...

(2) INFORMATION FOR SEQ ID NO: 425: -29 B-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA328 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 425: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 426:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 131 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA328 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 426:

AGGCTCCAAGATATTGCCCTGAGTATAGGCAGCAGGTTAAAAAAAAGTTA CTCTCATTAATTATTTTTAGAAAGATGGTGACAAGATGGACAGTACCTAA CTGTGAGATTGCTTTGTAGTAATAAGGCCTT

(2) INFORMATION FOR SEQ ID NO: 427:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA332 (up)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 427:

TGCTAAGTTGCTTCAGTCATGTCTGACTCTTTGCAACACCATGGAC (2) INFORMATION FOR SEQ ID NO: 428:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA332 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 428: TGTGTGTGTGTGTGTGTGTGTTATGTGTGCTGTG (2) INFORMATION FOR SEQ ID NO: 429:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA332 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 429:

GTCAGACATAACTGAGTGACTAAG

(2) INFORMATION FOR SEQ ID NO: 430:

(i) SEQUENCE CHARACTERISTICS: ' _3oo-

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA334 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 430:

GGGCGAGCTCGAATTCCCTCGTCAGTGGAGAAATGGGATTCAACTCAGGT AGTCCAATTCCAATGCTTTAATGACTTGTTTCTAAATGC

(2) INFORMATION FOR SEQ ID NO: 431:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 12 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA334 (repeat)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 431: π iiirpniπiiiii |"|"1"|"|"P

(2) INFORMATION FOR SEQ ID NO: 432:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 65 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA334 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 432:

ATTGTTATCTTTTCCCTCTTTGTATTGCTTGCAATACTTTCCAAACCCGA GGCTATGGCATTCGC

(2) INFORMATION FOR SEQ ID NO: 433:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA337 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 433:

AAAATAAAATAGATTATTTTTGTTAAGGATAGTAGGCTACTGACTAGGTT TGCTC

(2) INFORMATION FOR SEQ ID NO: 434:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 60 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA337 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 434:

TGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTAGTGGT GTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 435:

(i) SEQUENCE CHARACTERISTICS: (B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA337 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 435: AGCTCTTCCCTTGGTTTCCTTGAT (2) INFORMATION FOR SEQ ID NO: 436:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA339 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 436:

AAAGTCAGGATAGTTCTTGAATTCGGTCCCTACTTAACTCAGAATTTCTG GATA

(2) INFORMATION FOR SEQ ID NO: 437:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA339 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 437:

TGTGGTGTGTGTGTGTGTGTGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 438:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA339 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 438:

GAATTCCCTTGGTAGGCTGCAGTCCATGGGGTCGCAAGGAGTCAGACACA ACTGAGTGACTA

(2) INFORMATION FOR SEQ ID NO: 439:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA34 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 439: AGAATGGCTAAGCAGGCCAATCTAAGTTCCTGTTCTCTG (2) INFORMATION FOR SEQ ID NO: 440:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single -3o4~

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGIN.AL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA34 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 440:

ATATATATATATATATATATATATATATATATGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTG

(2) INFORMATION FOR SEQ ID NO: 441:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA34 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 441:

AAAGCATCAGTTCTTCAGTGCTCAGCTTTCTTCACAGTCCAACT (2) INFORMATION FOR SEQ ID NO: 442:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 153 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 442:

GTGAAGGACTGATCTGGATGCCACAGGGAGGGTAGGTAAGACATGAATAG GATACAGGCCTTCACCAACAGTTCACTGATTATGTCTGGGAAAATGCATT AGTGCAAGAGTTGAGATATGCAGAGAAGGAGCCCAGAAGAGATCCCTGAA GGA

(2) INFORMATION FOR SEQ ID NO: 443:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA340 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 443:

GTGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 444:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 162 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA340 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 444:

GGGAGCAGAGGAAAGTGATTCCACAGTGCCAGACCAAAGCCTGCCCTGCC ATGCAAGNCGCATCTGGGCATGTCTGCCGGATGTTTCCATGAGGACACCA GAGCATCCGAGAGAGGCTTCCTACCTTCCAGGCTGGCCACGCACCTCCAT CCCGCTCAGTAA

(2) INFORMATION FOR SEQ ID NO: 445: ~3θ6-

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA341 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 445:

AGCTATTAAGTATTTTCCATCCCAACAGTATGTTTTCTCTAGATGTTGGG GTAGTGAT

(2) INFORMATION FOR SEQ ID NO: 446:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA341 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 446: (TG)ll... (TG)16... (TG)5 (2) INFORMATION FOR SEQ ID NO: 447:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 86 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA341 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 447:

TTCTTCCTAATCTAGAGGGTTACAGTTTCATGAGCCCTGTGGATTAGTTA GTGCTGTGGCTTTTGATGAGACCAGGAAGAATT...

(2) INFORMATION FOR SEQ ID NO: 448:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 41 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA342 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 448:

AAGTGGCATTATTTCATTCTTTTTTATGGCTAAGATTCCAT (2) INFORMATION FOR SEQ ID NO: 449:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA342 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 449: TGTGTGTGTGTGTGTGTGTGTGTGCATGTGTGT (2) INFORMATION FOR SEQ ID NO: 450:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs -303 -

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA342 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 450:

CCTAAGACATGGAAGTGACCCTAAGTCCATTGACAGATGAATAAAGAAGA TGTGGT

(2) INFORMATION FOR SEQ ID NO: 451:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA345 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 451: TGTACTGAGCACGACTGGTCTTCAT (2) INFORMATION FOR SEQ ID NO: 452:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA345 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 452:

TGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATGTATA TATATA

(2) INFORMATION FOR SEQ ID NO: 453:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO . (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA345 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 453:

TTTAGTGTGAAAAATTGCTAGCAGAATCAAATGATCACTAAAGTTATCTA TAAGTTTCACTGAT

(2) INFORMATION FOR SEQ ID NO: 454:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA346 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 454:

TAGTAATTTCTATCTTCTCTTAGGAATCATCTTGCTTTCTGAAAAATCTT TTT

(2) INFORMATION FOR SEQ ID NO: 455:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs ' (C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA346 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 455: TGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 456:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA346 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 456:

TTCCTGCCTTTCTCTCATAACGACCCATGGAGTAATTTGTGGCTCAGGCA TCCACAGGATGATTTCATTTTTCTGTCCTCACAATGTGA

(2) INFORMATION FOR SEQ ID NO: 457:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA35 (up) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 457:

GCCAATCTGTTAATTTCTCTTTTAGCTGAATGGGGCATGGAAAGCA (2) INFORMATION FOR SEQ ID NO: 458:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA35 (repeat)

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 458: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 459:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 72 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA35 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 459:

TGGGCTGAGTAGTAATACCTGCCTCATGGGATGGTTCTGAGAGCTGATGG AGGAAGCATGCACATGTGCGTG

(2) INFORMATION FOR SEQ ID NO: 460:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single - 3.2-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA351 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 460: GCACATCTGGTGGCCACATCAGGTT (2) INFORMATION FOR SEQ ID NO: 461:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA351 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 461: TGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 462:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 130 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA351 (down) TGTTTCTGCAAGAAGTAAGATTCTGCAATCTTACTTTGAGACTATGGGAT CATGTACTCTAGGGGATTTCAGTCTCAGTGATTACAAACAAATCTGTCTT AAATATGTCTTCTTTTCTTTAACTTATTAA

(2) INFORMATION FOR SEQ ID NO: 463:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA353 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 463:

TTAATTATTTCTATTAATAGCCTTGGTTGGAAATTACTGAAC (2) INFORMATION FOR SEQ ID NO: 464:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA353 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 464:

TGTGTGTGTGTGTGTGTGTGTGTTTGTAAAANNNN.AAAAAAAAAAAA (2) INFORMATION FOR SEQ ID NO: 465:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 103 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear - 3.4-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA353 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 465:

TCCCCTAATTCTCAATACACATTCAGAGTTTTCCTAACCCCAGAAAGTAC ANNNCCTAATCATTTTCAAATCCAGGCTCCTCTTCCCTTTCTACATATTT AAC

(2) INFORMATION FOR SEQ ID NO: 466:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA354 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 466:

TCACCTTTCCCAAATAGATCCTAAGGTCCTTGAAAATCAGTTCATGA (2) INFORMATION FOR SEQ ID NO: 467:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA354 (repeat) -3.S-

TGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 468:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 149 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA35 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 468:

TGCATAAGAGAAACCACTACAAGGAGAAGCCCACACATGGCAACTAGAGT ACCCGTGCTTGCCAAATATAGAGATAGCCCATGTGCAGCGATGAAGACCC AGCACAGCCAAAAATAAACATTTATTTATTTATTTTTGGCTGTATGTAT

(2) INFORMATION FOR SEQ ID NO: 469:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA357 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 469: AGCTCAGAGGGCAAAAAGGTTTGGGGTGTATGGG (2) INFORMATION FOR SEQ ID NO: 470:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 30 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA357 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 470: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 471:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 71 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA357 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 471:

CCATGGTTTGTGCAGAGTCTGAGTTTAAACTTCTCTAACACCTTTGATCT CTCCCTCTGTCTCATCTAAGC

(2) INFORMATION FOR SEQ ID NO: 472:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA36 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 472: -3.7-

GATGAGAGGCTTCTCGTCACAAGGATGGTCCCCAGCTTAATGA (2) INFORMATION FOR SEQ ID NO: 473:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA36 (repeat)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 473:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 474:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA36 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 474:

GGGTAGCAAAGAGTTGAACATGACTGCATGACTGAGCAATTAACACGTG (2) INFORMATION FOR SEQ ID NO: 475:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA37 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 475:

TGACTTCCTGCTTTGCATTCCAATCCCCTATCCTGAGACATCTTT (2) INFORMATION FOR SEQ ID NO: 476:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA37 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 476: TGTATGTGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 477:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 125 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA37 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 477:

CCCGGTTCATTTCCAAGGCAAACCATTTAATATCACAGTAATCCAAGTCT ATGACACAGCTACTAATGTCCAAGAAGCTGAACTTGAATGATTCTATGAA - 3 *9-

(2) INFORMATION FOR SEQ ID NO: 478:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA377 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 478:

TGGTCAAGGCACTGTGTGGACTGTCATTATCTTCCAGCGGAGGGG (2) INFORMATION FOR SEQ ID NO: 479:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA377 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 479: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 480:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 152 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA377 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 480:

ACCGTCCCATAACCAGTTATACGGCAGAACTAGAGAAGGATTGCACTTCG CTTTTCTCCCATTCTGTGTTGCTGCTGCCCATGATGCTGTCTGTCAGGTC CGGG.AAATAGACTTTGGATCTCTGGTTGAAATGGCCAGCAGTTCCTGATT AT

(2) INFORMATION FOR SEQ ID NO: 481:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA378 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 481:

CCTTTTATAGCCAACCATATACTTTGCCTAAAAATCTTTCTTCAGGTAAG AACA

(2) INFORMATION FOR SEQ ID NO: 482:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA378 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 482: (2) INFORMATION FOR SEQ ID NO: 483:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA378 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 483:

TTTCCTGCTCTTCACCATCCATACCTTTTCCCGTAACTCAGTACCTCTCA ACTTCATGTATGT

(2) INFORMATION FOR SEQ ID NO: 484:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 74 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA380 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 484:

CCAAATGCCTGCTGGTACCTGCTTAAGTGGTAACCAGGCAACCAGTCAGC ACACTGTTTTCATTAAAATCTTTT

(2) INFORMATION FOR SEQ ID NO: 485:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA380 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 485: TGTGTGTGTGTGTGTGGTGTGTG (2) INFORMATION FOR SEQ ID NO: 486:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS:^' single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA380 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 486:

TTTTATTTAAAGTGTAGTAAGGTTAAAAATGTGATTATGTAAAGTAGTTT T

(2) INFORMATION FOR SEQ ID NO: 487:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 159 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA381 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 487: CCTGTAGGTGAGAATNNTGTAGTCAGGGGCTATGAGACTTAGTAGAGTCA GATAGAAGAGTTCAGGACTTCAGTCTCCAAAGGTGTGAATTAAATTACCA TATATCTGTATATCTGAAGTTTTTATTTTGGTGGGGATTTTCTTTTAGTG TATTGGTGC

(2) INFORMATION FOR SEQ ID NO: 488:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA381 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 488:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 489:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA381 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 489:

TTGATTCCTTTTAAACAAGATTTTAAGATCTTGTTTAGGGGAGTCTACAT CT

(2) INFORMATION FOR SEQ ID NO: 490:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 115 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -32.4-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA382 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 490:

CTCCGGCAGTCCAGTGGTTAGGACTCCAGGCTTTCACTGCCAAGGGTGCC AGTTTGATCCCCGAATGGAACTAAGATCCCACAAGTCATGCAACTTGGCC TAAATAAACAAAGCC

(2) INFORMATION FOR SEQ ID NO: 491:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA382 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 491: GTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 492:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 81 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 492:

TTAAGTGCCCAGTTCAGTGGCACTAAGTCCACTCCCATCGTTGTGCAACT GGCACCACCATCTATCCATAAAACTCTTAAA

(2) INFORMATION FOR SEQ ID NO: 493:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 149 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA387 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 493:

CCTCAGATGGTAAAGAATCTGCCTGCAANNNNNACCCAGTTTCAATCCCT GGTCTGGGAAGATCCCCTGGAGAAGGCAATGGCAACCCACTCCACTATTC TTGCCTGGAAAA...AACCATTCAAAGTCTTAGAATAAACTGGATGGTG

(2) INFORMATION FOR SEQ ID NO: 494:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 13 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA387 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 494: A14... (TG)IOT (2) INFORMATION FOR SEQ ID NO: 495:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid C STRAND NESS: sin l (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA387 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 495: TTTCTCTGTCCCTTTGTTTACTTTGATAAAACTCTGCT (2) INFORMATION FOR SEQ ID NO: 496:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 136 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA39 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 496:

AATGATATTAGCAGAAATACTGTCATTTTGGATTAAAAGAAGTAGACACA GTACAAAATGGGAAGGGGCCATCAGAACCCAGAAATTCTACTCGTAAGAA GCGGGCCAGGAAAACTATTCAGGGGCAAGCATGCAT

(2) INFORMATION FOR SEQ ID NO: 497:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -32.7-

(B) CLONE: TGLA39 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 497: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 498:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 109 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA39 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 498:

GGGCATTGTGAACCACTCCAGTACTCTCGCCTTGAGCATTCCATGGACAG AGGAGACTGGTGGGCTACAGTCCATGGACTCTCAAAGAGTTGGACATGAC TGAGAAACT

(2) INFORMATION FOR SEQ ID NO: 499:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA394 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 499:

AATTTTAAGTGTCAGTCTGACTGGGTCATGGGATATCCAGATA (2) INFORMATION FOR SEQ ID NO: 500:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 11 base pairs

(B) TYPE: nucleic acid (C) . STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA394 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 500: TGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 501:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA394 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 501:

CTTTACTCAGTCTCACGATTTACATGCTAATCTCATCCAGAA (2) INFORMATION FOR SEQ ID NO: 502:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE : DNA (genomic) (iii) HYPOTHETICAL : NO (iv) .ANTI-SENSE : NO

(vi) ORIGINAL SOURCE :

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA4 (u ) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 502:

ATCAGACTGTTGTCACTGTTTAAACCAGTACTCAGCCCACTTGA (2) INFORMATION FOR SEQ ID NO: 503:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA4 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 503: GTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 504:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 97 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA4 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 504:

TTCAGTGCCTGGCAGCAACCTCATTTCTAACACATCATTACATTTGCCCA GAGTGCCCTTGAACGCCAGGTACAAACTTTACAGGGACTGTACATAT

(2) INFORMATION FOR SEQ ID NO: 505:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear ii MOLECULE TYPE: DNA enomic (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA40 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 505:

TTTTTACCCATTTAGCTTCTCTGCCAACTAATATTATCCACTATCTACCT ACATA

(2) INFORMATION FOR SEQ ID NO: 506:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA40 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 506: TGTGTGTGTGTGTGTGTGCGCGCGCACA (2) INFORMATION FOR SEQ ID NO: 507:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA40 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 507: _33l-

TACTTCTGAGCCACCAGGTAAGCCCCTTATATATGTGTGCATGTTTACAC ATGCA

(2) INFORMATION FOR SEQ ID NO: 508:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA400 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 508:

CCTGCCTTTGTGATATCTAAGCAGAATATCAAGTTGGCAG (2) INFORMATION FOR SEQ ID NO: 509:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA400 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 509:

GTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGTCTGTGTCTGTGT (2) INFORMATION FOR SEQ ID NO: 510:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA400 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 510:

TTCTGGTAATTGAAGTCATCCATTTCATGTTTGGTATATATGCCATTTGT T

(2) INFORMATION FOR SEQ ID NO: 511:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 158 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA414 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 511:

TGTAGGGATAAAATAATTATCCCTAATACTTTGATATTATACAAATATAT AAAATCCATATTTATGTATGACTAATAAGAGTTTTTGAGTTNGGAATCTT GACATCTGTCTTACCTCGAACTTTATAGGGCAAATTTAAACTAAAAAATG GAAAC...

(2) INFORMATION FOR SEQ ID NO: 512:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA414 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 512:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATGTGTGT (2) INFORMATION FOR SEQ ID NO: 513:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA414 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 513:

AGCTGAATGAANGTACAAAATCAATCTGTCAGTTCTTTTCAACCCACTAT (2) INFORMATION FOR SEQ ID NO: 514:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA415 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 514:

CCTAAAAATCCTCCTCTGTTATCAATAGAGATATGCATTTAGAANGCC (2) INFORMATION FOR SEQ ID NO: 515:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA415 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 515: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 516:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA415 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 516:

AAGGAGCCTGGTGGGCTACACTTCATGCGGTCACAAAGAGTCAGACACAA CTGAGCAACTAA

(2) INFORMATION FOR SEQ ID NO: 517:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 195 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA417 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 517: TTTTATAGAAGAAAGGTAATGAAACACTTGATTCTATACCTTCCTGCCCA AATCTCTTCAAAAGATTNNNNTCACAGAGTTACCAGTATAAAGGAAATCA TTTCTCAACCATCTTGCACATGCAGAGGCTTATTCCAGATATATTTACAA ATTTGCCTATTACCAATTTATAAAGAATCATTTCAATGAAAG...

(2) INFORMATION FOR SEQ ID NO: 518:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA417 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 518: TGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 519:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA417 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 519:

GCTTCAGTCCATGGGGTTGCAAAGAGTCAGACTCAACTGAGCAACTGAAT (2) INFORMATION FOR SEQ ID NO: 520:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 199 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear ~ 33<c -

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA419 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 520:

CTGTGCCAAATGTTCACACTGTGTTTAGGTATCCAGGCTCAGGAGTTAGA CATCTGAATAGTTCAAATCCCTGCTCTGCTACTTATAGGCTTTGAAAATT CTGAGCCTTTCTCGTTCTGTTCCCTTATCTGTAAAATAGGAATAATTTTA TAGG...CCATAGCACTTAGCACCAGTTTGGCACATAATAAGTAAATTC

(2) INFORMATION FOR SEQ ID NO: 521:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA419 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 521: GTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 522:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 522:

GGCTACAGTCCATGGAGTTGCAAAGAGTCAGACACAACTGAG (2) INFORMATION FOR SEQ ID NO: 523:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 70 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA420 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 523:

TGCACCCATCAGTATTTTCCTAAATTTTATACTATGGTCTAGTGTCAAAC AAAATGTTTTCATTTCTTTC

(2) INFORMATION FOR SEQ ID NO: 524:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 13 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA420 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 524:

(2) INFORMATION FOR SEQ ID NO: 525:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 173 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -33b - (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA420 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 525:

TTTGCTGGTTTGATCTCTTTGATGTTCAAAGGACTTTCAAGAGTCTTCTC CAGCATCACTGTTTGAAAGCATCAATTCTTT...AACCTAGAAGTCTAGC AATAAATTTTTTGTTTGCATTTGCTTTCTCCAAACTTTTTTGACGTGGGA TCACATTTTGGGTCACATTTTTG

(2) INFORMATION FOR SEQ ID NO: 526:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 125 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA421 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 526:

ACGGTCCCCAGCGTTCCCTGGACCTTCATTCCATAGCCTGAAAGGGAGCA GCCCTTGGAGTCTATGTCCATCCACCCCAGGTTCATTAGTGACATGGGGG CAGGAACAAGGTGCTTTGTAAA...

(2) INFORMATION FOR SEQ ID NO: 527:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 35 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA421 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 527:

GTGTGTGTGTGTGTGTGTGTGTGTAAGAGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 528:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 105 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA421 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 528:

TCAACTCCGAGGGCTCTGCTGGGCAGCCCTGCCCTTCGCTGAGCCCTCAT CTCTGCCTCACACCCTCGTACTTGCCGTGTGTCTGACTGTACTCCTCACC CATGG

(2) INFORMATION FOR SEQ ID NO: 529:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 108 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA423 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 529:

CCTCTATTTTTGACCAAAGCAGTGGTGTTAGATATAGATTTAAATCTGTA TAGATGTATATCTTTGGGTAGATATAGAAATAGATCCCTATATATACTAA ACAGATTT

(2) INFORMATION FOR SEQ ID NO: 530:

(i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA423 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 530: TGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 531:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 109 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(Vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA423 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 531:

CAATTCCACGTNTCCCCAGAAAAACCCTTTTGCCCAAGAGATGGCTTTGT CTTCTCTCAGAAATATATATTGCTTACCAGAT...GTCACATACCCACAT AGGTGC...

(2) INFORMATION FOR SEQ ID NO: 532:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 140 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO (A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA424 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 532:

TTTCTGAATGACATAGAAAGCATTAGAAAGTTTTAANGAGAGGAGAACAT GGTTTGGCTTACATATTCAAAGGCTCATCAAGGNCTGCTTTGTGGATAAC GGATTGTAGGAGNCCAACTATGGAATGCCAGGAAAAG...

(2) INFORMATION FOR SEQ ID NO: 533:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA424 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 533: TGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 534:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 88 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA424 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 534:

AATAGCCGCAGAAAGGAAATATGATCCATATATGCTGTATAAATATGTTT ACTCCAGTATTCTTGACTGGAAAAATCCCATGGAA...

(2) INFORMATION FOR SEQ ID NO: 535: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 119 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA427 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 535:

GCCACCTTCTCATCAACAAATCCATGCAAGCGTTCTCTGCATTATGCCGC TTTTCACTCACAAGTTTTATTTTTCACTAGAGAAGCACTTAGCCCAAATA AGACAATTTGCTGTGGAAC

(2) INFORMATION FOR SEQ ID NO: 536:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 13 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA427 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 536: (TG)11T...T15 (2) INFORMATION FOR SEQ ID NO: 537:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA427 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 537:

CCTCACTGCAGTGCTCCTATTATGATAATGGGAATTTATGCACATGAGTA TTT...

(2) INFORMATION FOR SEQ ID NO: 538:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 175 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA429 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 538:

CTTTCCTAGACTGTGGAAATGCTAAGTAGGAACTATTTCCTTCCGGTATT TTAAATCTAAAATTTTTGTCTTTCAGCATTTTTCCCTCTCTCCTTCTCTT GCAATTGACAGTCTGTGGTATAACTTCTTTTTGAAGTTAGTAGTAGATTA TAATTCTTGGTTTTGGGTAAACAAA

(2) INFORMATION FOR SEQ ID NO: 539:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA429 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 539: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 540:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA429 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 540:

ATCTCCTAGAACCTGTCCTCCTACTGGTNTGAAGAGAATGGCTAATAAGA AGAGTTAATCT

(2) INFORMATION FOR SEQ ID NO: 541:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 57 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA431 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 541: ACTATTTATTTAACAAGGTCATATCCTTCAAAATTTACTTACAGAGGCTC

AAAGAAC

(2) INFORMATION FOR SEQ ID NO: 542:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) i 34s-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA431 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 542: GTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 543:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA431 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 543:

CTAAGGAAAATTTCCCATTTATTCCTAATTTCAACTTCAGGATCTTTTAT GTTTCTGACACTCGAAGTGAGCAAACAAAT

(2) INFORMATION FOR SEQ ID NO: 544:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 60 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA432 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 544:

AATTGTCTTCCATGAAACCACTCCCCTGATGCCAGAAAGATTGGAACTCC TGTCTAA... (2) INFORMATION FOR SEQ ID NO: 545:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA432 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 545: TGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 546:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 60 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA432 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 546:

GAATTCTGTGGACAGAGGAGCCTAGCAGGTTACAGCCCATGGGGTCGCAG AGTCAGACAC

(2) INFORMATION FOR SEQ ID NO: 547:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 184 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA433 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 547:

CTAAAAATTAGGGCCCTTTAACTATAGGCAGGAAACTGCATTGCTGAACA GTATGTAGATNTCGAAGTGATCTGATTTCTATGAAGTAGTCTTCTGACTT CTATGAAGATTGACTGTAAATGTTAATTATAACTTTTATTATTTACTTTA TTTTTCTACTACTTACACAAAATTAACTATGG..

(2) INFORMATION FOR SEQ ID NO: 548:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA433 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 548: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 549:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 66 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA 33 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 549:

AAATAGTGAAATGACATGTTACTTAAATATAAGGACTATTTTAAAACTAG TCACGAGTGCCTGCAA (2) INFORMATION FOR SEQ ID NO: 550:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA435 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 550: TGCATGTATACTCATCATTAATATTGGTCTGTAATTTCC (2) INFORMATION FOR SEQ ID NO: 551:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA435 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 551: TGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 552:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 84 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA435 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 552:

AACTTGCAGAGGAAGGAACACATTCAAACTCATTCTATGAGGCCAACATC ACCCTGATACCAAAACCAAGCAAAGATATCACAT

(2) INFORMATION FOR SEQ ID NO: 553:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 87 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA436 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 553:

AGTATGATAATCTATAGATTCATTCATGTTGCAGCAAGTAGCATTATTTC ATTCTTTTGTATGGCTGAATGATATTCCATTTGTGTT

(2) INFORMATION FOR SEQ ID NO: 554:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA436 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 554: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SE ID NO: 555: -35C-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA436 (down)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 555:

GTACCTGTCTACTGACAGATGATTAGATAAAGAAGATGGGTTAATAT (2) INFORMATION FOR SEQ ID NO: 556:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA437 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 556: CTGCATGGTATTGGTGTACAGATCAGGTAAA (2) INFORMATION FOR SEQ ID NO: 557:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 86 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO (A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA437 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 557:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTATGT GTGTGTATGTGTGTGTGTGTGAGAGAGAGAGAGAGA

(2) INFORMATION FOR SEQ ID NO: 558:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA437 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 558:

ATGCCCTTCTCCAGGGGTTCTTTCTGACCTAGGGATCGAACCCAGGTNTC CT

(2) INFORMATION FOR SEQ ID NO: 559:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 147 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA438 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 559:

GCAGGATTGTTTTGATTACTTAACCATCACTCTAATTTGCTATTCAGCAG NGCCTATTCTATTATTCTATTTATTGACTTTTTATTCCAACAATTAGATT TTCATTTTCCTGATCTCTAGTTTATTTCTATTGATGAAAGAGAAATA (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA438 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 560:

TGTGTGTGTGTGTGTGTGTATATATATGTGTATATATATATATATATATA TATATATATATATA

(2) INFORMATION FOR SEQ ID NO: 561:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA438 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 561: CTCAGATAAGTACTCTTAATATACTCAGGCAGTA (2) INFORMATION FOR SEQ ID NO: 562:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 90 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA44 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 562:

GTCTATACTGAACTGTATATTGAGAGCCTACCATGTGTGAGATGTGAATG TATGATATATATTCTGAGCCACTGGGGAAGCCCAGTCTGG

(2) INFORMATION FOR SEQ ID NO: 563:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA44 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 563:

TATATATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTG

(2) INFORMATION FOR SEQ ID NO: 564:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA44 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 564:

ACAGTCCATGGGGTCACAAGAGTTGAGCACAACTTAGCGACTAAACCACC ATACC

(2) INFORMATION FOR SEQ ID NO: 565: -35^"4-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA441 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 565: CTTGCAGGCCAAGTCATCTGAATTTAATATACAGATTGA (2) INFORMATION FOR SEQ ID NO: 566:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA441 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 566:

GTGTGTGAGTGTGTGTGTGTGTGTGTGTGAATGTGAGTGTGTGTGTGTGT CGCGTGTGTGT

(2) INFORMATION FOR SEQ ID NO: 567:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 100 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA441 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 567:

TTGCATAGTTTCAATGTGTCTGCACTGGGTGTCATCCAATACTTATTATA TAACTTTTCACAACTGGTAAAATGGCAGTGGCAGTGTTTTTTTGTCTTTA

(2) INFORMATION FOR SEQ ID NO: 568:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 183 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA443 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 568:

TTTGCTAAAATATGTTTTGAGGTATTTTTAAGATACAGTTTTTAACACAA CTTAGGAACTTCCATTTGTTTATAGTCACAATATCATCTGAAGCAATGGA TACAGGTTGAGATAATCCTGAATTAAGGAAGGTCCTTGTTTGCTGCTGTT ACTATGGCAACCTGCTGCCACCTGGTGGCAGTC

(2) INFORMATION FOR SEQ ID NO: 569:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 137 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA443 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 569: ^•354--

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNNNNNrøNNNNN NNN NNNNNNNNNNNNNNNNNNNNNNNTGTGTGTGTGTGTGTGTGTGTGTGNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNT

(2) INFORMATION FOR SEQ ID NO: 570:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 31 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA443 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 570: CTTGGCGGGCTACAGTCCAGAGGGTTGCAAA (2) INFORMATION FOR SEQ ID NO: 571:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 114 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA444 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 571:

GTGGGAGCCTCTTGGTGAATCATTTGCAAAATCTAAGCATNCTCACAGCA CAAAGCAGATGTTTATTATATGTCATGTAATGGGGAAATTATTGTTCTTT GTGCATTCATCTAA

(2) INFORMATION FOR SEQ ID NO: 572:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA444 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 572: GTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 573:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 192 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA444 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 573:

CTGATACCTCTGATATTCTGCATAGTCTTGGAATTAGATCTAGTTTTCAC CAAATTGAGAAATGAAAAGATGCCCCTCCCCTACACACAGTTGTCTGGAT AGTGTTAGAGCAAAATTAATCTTCTAACTATTTATGTTAAAAAATGAATG AAGTAACAATGAAATAACTCTTTTTCAGACCTAGAAATACAT

(2) INFORMATION FOR SEQ ID NO: 574:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 116 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: - 35β ~

(B) CLONE: TGLA445 (up)

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 574:

CTAAGTGAGGGAGCCATGGCTGGAACTCAGACTCTTTTTTCAGGTCAAGA TACCTTAAAACAAGATATATTCTAAAAGCATTATTTGCTCATCATAAAAT TGTAAGCCACATGGAA

(2) INFORMATION FOR SEQ ID NO: 575:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA445 (repeat)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 575: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 576:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA445 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 576:

GCAAAGAGTAGGACACAACTAGTGACTTTCACAACAATGCAT (2) INFORMATION FOR SEQ ID NO: 577:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 132 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA446 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 577:

CTGCAGTAGATTGTCATTTCTTCCTCCAGGGAATGTTCCTGACCCAGGGA TTGAACTCGTATCTCTTATGTCTCCTGCATTCAAAAGCCAGTTCTTTACC ACTAGCACTACCTGAGAAACCCAAAAAAGACG

(2) INFORMATION FOR SEQ ID NO: 578:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA446 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 578:

GTGTGTATGTGTGTGTGTGTGTGTGTGTATGTATGTATGTGTATTTTTTT T

(2) INFORMATION FOR SEQ ID NO: 579:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 34 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -3£o-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA446 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 579:

CTTAGGGTTGCAAAAAGTTGAACATAACTGACTG

(2) INFORMATION FOR SEQ ID NO: 580:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA45 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 580:

TTTTATAACAGTTGCTTGTGGCAAGAAAGAGCTTTGTCAGTCAGAAGATG CAGTTGAAAAATA

(2) INFORMATION FOR SEQ ID NO: 581:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA45 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 581: TGTGTGTGTGTGAGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 582:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 103 base pairs

(B) TYPE: nucleic acid - 3^(pι -

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA45 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 582:

CCAACTTCCTGCCCTCAAAATTGATGTGTACCAAGGCAAAAAGGCAGGAA GCAAAACCCACAAAACGCTGTTTCTGAGGCGAACGTGACATTAAGACTGT ATG

(2) INFORMATION FOR SEQ ID NO: 583:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 60 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA47 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 583:

GATCTGAAATTTGATTCTTCTACTTCCTCAAGTGAATTTCCCCCTTTTTT AGTTGCCAGG

(2) INFORMATION FOR SEQ ID NO: 584:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA47 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 584:

GTGTGTGTATGTGTGTGTGTGTGTGTG

(2) INFORMATION FOR SEQ ID NO: 585:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA47 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 585:

GGAGCATCTCCTGGAGAAGGAAATAGCAACCCAACCATATTATTTATTTA CGTTTTTAAAATTTTTTCATCATGTTTTAT

(2) INFORMATION FOR SEQ ID NO: 586:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 83 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA48 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 586:

GTATTTTATTTATCACAGAGTTTTGCAGTAATTTGATTTTTAAGTAGTTT ATTAAAATGTTTTATCTTGACTACTAAGCATTT

(2) INFORMATION FOR SEQ ID NO: 587:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs ^■3 c3 -

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA48 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 587: TGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 588:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA48 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 588:

TGCAGCTATAGTCCATGGTGTCACAGAGTCAGACATGACTCTGCCATAGA GCATG

(2) INFORMATION FOR SEQ ID NO: 589:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -3G^»*4-

(B) CLONE: TGLA49 (up) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 589:

TGCTGCAAGTGGCAGGACTTCACTCTTTTTCATGGCTGAGTAATATTCG (2) INFORMATION FOR SEQ ID NO: 590:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 26 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA49 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 590: TGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 591:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 46 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA49 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 591:

GAATAATGAGCACAGATTAAAAAAGAGATGATTTGTGCATGCA... (2) INFORMATION FOR SEQ ID NO: 592:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 107 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear - 3l S-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA5 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 592:

ATCATGGAATTTTTCAGGCAAGAGTACTGGAGTGGGGTGCCATTGCCTTC TCCGCTACCCACCTATACTTAGTGGGTTATTTCACGGCTTCCCTTTGGGC CACCTCT

(2) INFORMATION FOR SEQ ID NO: 593:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 52 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA5 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 593:

(TGGAAAGAGGAGC(CG)N(TG)N(TA)N(TG)N(TC)NACTCAGTTATG )N

(2) INFORMATION FOR SEQ ID NO: 594:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 98 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: ' -3<e«i>-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 594:

TGGATGAGGGCATGGCAAGCCACTCCAGTATTCTTACCTGGAGAATTCCA AAGACAGAGGAGCCTTGTGGGTAAGATACAACTGAGCAAAGAGTTGGA

(2) INFORMATION FOR SEQ ID NO: 595:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA51 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 595:

GTGCTGGTCCAACATTGCTTCTTTTAAGGTTATCTGCCACCTAAGAC (2) INFORMATION FOR SEQ ID NO: 596:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 68 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA51 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 596:

TGTATGTATGTATGTATGTATGTATGTATGCATGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTGTG

(2) INFORMATION FOR SEQ ID NO: 597:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA51 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 597:

TGGATAGAGGAGACTAGCAGGCTACAGTCCTTGGG7TCGCAGAGTCAGAC GTGACTGAAGC

(2) INFORMATION FOR SEQ ID NO: 598:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA52 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 598:

GATTTCTGGTCTGTTTAGTGCTTTTTAATCCCTCAGCTTGCTGGAGC (2) INFORMATION FOR SEQ ID NO: 599:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA52 (repeat) -3£S-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 599:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 600:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA52 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 600: CTCTTGGAAACTGCTTCCAAAACTTTACAATATGTATTT (2) INFORMATION FOR SEQ ID NO: 601:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA53 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 601:

GGCTTTCAGAAATAGTTTGCATTCATGCAGAACATAAAACTA (2) INFORMATION FOR SEQ ID NO: 602:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA53 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 602:

TGTGTGTGTGTGCGTGTGTGTGTGTATATATATATATATG (2) INFORMATION FOR SEQ ID NO: 603:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA53 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 603:

GATCTTCACATGATATTACAGCAGACAGCTGCAAGAGTTAGCAAAAGTAT TACTATAGG...

(2) INFORMATION FOR SEQ ID NO: 604:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA5 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 604:

ACTATACTCAATATTTTGCAATAACATATAAGGAAAAAGAATCTGAAAAG GAA (2) INFORMATION FOR SEQ ID NO: 605:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA54 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 605: TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 606:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA54 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 606:

ACGATATCATGTTAGTTTCAGGTGAAAAAACACAGCAACTCAGTTTTGT (2) INFORMATION FOR SEQ ID NO: 607:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA58 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 607:

GATCTGANNGTGCATGGACAATAATTCTACTCTCCACNNNNCTCCCTTGC (2) INFORMATION FOR SEQ ID NO: 608:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 57 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA58 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 608:

TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTG TGTGTGT

(2) INFORMATION FOR SEQ ID NO: 609:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA58 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 609:

GTGTGTATAGTCAGCAGCAGTGTTGGCTCCAAGAGCAAGTAAAGTGGTGT G (2) INFORMATION FOR SEQ ID NO: 610:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA6 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 610:

AGGCAAATAGGCACAATGTCAATAATTTACTCTTAACAGTTCAGTAATAA ATGTAATGATATGTNANCTAATCCAC

(2) INFORMATION FOR SEQ ID NO: 611:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA6 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 611:

TGTGTGTGTGTGTGTGTGTGTGCACACGCACATCTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 612:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 87 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA6 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 612:

AGAATTCTTATTCCTACTTACCTTTCACACAGAATTCTCCATGTTAAGGG TTTACCATGTTTGCTCTGCTCTTCTCCATCCCCTCTG

(2) INFORMATION FOR SEQ ID NO: 613:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60A (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 613:

TAGAAGAAATACTAGACAGTCCTCGAGGGTGAAGTAAGAGGGATGTGTAC CTAAGGGGAAAA

(2) INFORMATION FOR SEQ ID NO: 614:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60A (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 614: TGTGTGTGTGTGTGTGTGTGTGTGTGAAATGTGTGT (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60A (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 615: GCAGCAGATCTTTACCGTCTGAGCCACCAGGGATGTAT (2) INFORMATION FOR SEQ ID NO: 616:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 64 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60B (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 616:

ACATTCTCATCTGGAAACCATGGTGGTCAAAGAGCAGTGGGATGACATTG TACATCATGAAGAG

(2) INFORMATION FOR SEQ ID NO: 617:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO iv NT - (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60B (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 617: AAAAAAAAAAAAAAAAAA (2) INFORMATION FOR SEQ ID NO: 618:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 33 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60B (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 618: TTTTGCTTGATATAAAATTCTTAGTTGACAGTC (2) INFORMATION FOR SEQ ID NO: 619:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 85 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA61 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 619:

ACTTAGGGGAAGGTAAAGACTACCCACATTTCAGTCCTTGAAATAGTAAA AAGACCATATTTTTTAATCATCCAAGAGAAGCCAG

(2) INFORMATION FOR SEQ ID NO: 620: (A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA61 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 620:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 621:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA61 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 621:

AAATTGAGTTAATTGCCAACATTGGGCAATCTGGATACCTGACATAAGAT (2) INFORMATION FOR SEQ ID NO: 622:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 67 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA66A (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 622:

ATCAGAATTTAGCATCCTTGCTGAGACTCAGTTTCACCACATGAAAACAA GATAATCATTAGAGATA

(2) INFORMATION FOR SEQ ID NO: 623:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 58 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA66A (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 623:

TGTGTGTGTGTGTGTGTGTGAGAGAAAGAGACAGTGTGTGTGTGTCTGTG TGTATGTA

(2) INFORMATION FOR SEQ ID NO: 624:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 13 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA66A (down)

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 624: GATCACTGTTATG (2) INFORMATION FOR SEQ ID NO: 625:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs n leic acid (C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA67 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 625:

CAGAAGGCTCTTGTGTCAAGTAAGACTGTTCAAAAGGGCCAATCCTAAAA GTAC

(2) INFORMATION FOR SEQ ID NO: 626:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA67 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 626: TGTGTGTGTGTGTGTGTGCGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 627:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA67 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 627:

CCATAAACAGAGGAGCCTGGTTGGACTATGCATATTCCATAGACTATGGA ATTGCAAAGAATTGGATGCGACTGAG

(2) INFORMATION FOR SEQ ID NO: 628:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA68 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 628:

TTTACTTCACTTCCAGGAGATGGTTACCAGTATCTTACTTACCTTCTCAG AGCTATACATATC

(2) INFORMATION FOR SEQ ID NO: 629:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 49 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA68 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NC: 629:

TGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATAT (2) INFORMATION FOR SEQ ID NO: 630:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 54 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA68 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 630:

CTACCATTTGTACCAAAAAGAGGGACAAAATTTTACATATACACTTATCT GCTC

(2) INFORMATION FOR SEQ ID NO: 631:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA69 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 631:

AATAACACTATCAAACTGCAAAACTGTTCCCGATTGATGGATGCAATGCA TTGAC

(2) INFORMATION FOR SEQ ID NO: 632:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus - 3.31-

(B) CLONE: TGLA69 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 632: TGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 633:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 40 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA69 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 633:

ATGACTAGATATTTATGTTCCTTTCAGATATGTCAAATAT (2) INFORMATION FOR SEQ ID NO: 634:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 89 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA70A (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 634:

ACAGGCTATTCTAATATAAAGACTATTTACCATTAAGTAAAATAAGCAGT TTGTATGGGGCAGGTATATAATAATGATATCCATGTGCT

(2) INFORMATION FOR SEQ ID NO: 635:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 13 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -3B7-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA70A (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 635: AAAAAAAAAAAAA (2) INFORMATION FOR SEQ ID NO: 636:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA70A (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 636:

GTGGATTGCTGTGCTCTCTTCAAGATATGTTATAGGAGGGTG (2) INFORMATION FOR SEQ ID NO: 637:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA70B (up) AGGTGTAGAGTTGAGAAACTTGCATTTTGGAACCTGTGGTACGAA (2) INFORMATION FOR SEQ ID NO: 638:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 26 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA70B (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 638: TGTGAAGCGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 639:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 62 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA70B (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 639:

ACCTTGCAAGATTTCTCTACACCATTCCAAAAGAAATGGAACTCCCTGTA ACCACTCCATCT

(2) INFORMATION FOR SEQ ID NO: 640:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 39 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA72 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 640: TCGAGCTCGCCGGGGATGGGTGGGTCTGAATGAGGTGGA (2) INFORMATION FOR SEQ ID NO: 641:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 114 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA72 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 641:

CCCCCCTTTCTCTCCTCCCTCCACAGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTACAGAGAGAGAGACAGAGACAGACAGAGACACGGA GACTATATATATAT

(2) INFORMATION FOR SEQ ID NO: 642:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 70 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA72 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 642: TCATTTAAAAGTGGATAAGCTTTGCAATGCAAACAGGCAGAGGGCATGAG TAGGTATTTCACAGGAAAGG

(2) INFORMATION FOR SEQ ID NO: 643:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 76 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL' SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA73 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 643:

AAAGAATAAGCTGTGGGTAGTAGTGGCATAGAGAGAGGAGAATCACCTAG AGAGGCAAAAATAACTCAAAACACTG

(2) INFORMATION FOR SEQ ID NO: 644:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 45 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA73 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 644:

ATATATATATGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTATATA (2) INFORMATION FOR SEQ ID NO: 645:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 30 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear - 306-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA73 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 645: GCTTCTTTCTCTTTAAATTCTATATGGTTT (2) INFORMATION FOR SEQ ID NO: 646:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 108 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA75 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 646:

GGCTGACTGGTCTCCCCAACGCAGACAATTCTCCACGCTTTCACTCTCCA AATCTTTAGGACTGATAGTTTAACTTGAGGAGATTGCCTCTTCCAGATGG TTCTTTTT

(2) INFORMATION FOR SEQ ID NO: 647:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 73 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA75 (repeat) -3.97-

ATGAGTGAGTGAGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGAAAGAGAGAGAGAG

(2) INFORMATION FOR SEQ ID NO: 648:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA75 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 648:

GAAAGGGAAAAGAGACAAAACCAGGTAAATCTTTCTACATGTCTTACCCT ACA

(2) INFORMATION FOR SEQ ID NO: 649:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 72 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA76 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 649:

AGCATGGTGTCTTAGCCACTGGACTGCCAGGAAGTCCAGTATTTCATTCT TTTTAATGGCTTAGTAATATTC

(2) INFORMATION FOR SEQ ID NO: 650:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -326-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA76 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 650: TGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 651:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 63 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA76 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 651:

AAACAACCTAAATGTCCATCAGTAGATGAACGGATAAAGAAAATGTGGGT GATACATATACAT

(2) INFORMATION FOR SEQ ID NO: 652:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 51 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA77 (up) -369-

AATTGAATAAAAGACAGGAGATGCTCAGGGATGGTTCCCATAGCAACTGC A

(2) INFORMATION FOR SEQ ID NO: 653:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA77 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 653: GTGTGTGTGTGTGTGTGGTGTGT (2) INFORMATION FOR SEQ ID NO: 654:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 53 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA77 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 654:

AGCCTCACGCATGAAGATGAGCTGCTATTTCTCTTCTAATGCATATATTA AAT

(2) INFORMATION FOR SEQ ID NO: 655:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 97 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA ( enomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA78 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 655:

CCCACTGATAAACAATGACTAAAAGTTTTTATTATTATAGTATAATTTAT TTACAATGTAGTGTTAGTTTCTGCTGTACAACAAAGTGACTCAGCTA

(2) INFORMATION FOR SEQ ID NO: 656:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 32 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA78 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 656: TGTGTGTGGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 657:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA78 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 657: -39ι-

GATCCTCGTCATGACCTAGAGGGGTAGGATGGGGGTATGAGGTGGGAGGG AGATTCAAGAAGGAGGGGATATGTGTATAA

(2) INFORMATION FOR SEQ ID NO: 658:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 42 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA79 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 658:

CAGCTAAGCGACTAACACTTACTTACTTATTCTTCCCATAAA (2) INFORMATION FOR SEQ ID NO: 659:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA79 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 659: GTGTGTGTGTGTGTGTGTGGGGTGGTGGGGGGGTGT (2) INFORMATION FOR SEQ ID NO: 660:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 80 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA79 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 660:

AAATAATGTGGCAAGAATCCCAGGGATAGAGGAGCCTGGGGTATATTGCC ATATTGGGAAACTAAACTCATTTGACAAGA

(2) INFORMATION FOR SEQ ID NO: 661:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA8 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 661:

CTGAACTGACAGGCAGGTTCTTTACCACTCGCTTCACCTGGGAAACC (2) INFORMATION FOR SEQ ID NO: 662:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 70 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA8 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 662: ATATATATATATATATATAT (2) INFORMATION FOR SEQ ID NO: 663:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 102 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA8 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 663:

ACTGGACTATTTTACAGTGCCAAGCATCAGTGTTTGATGCATGCATTAAG AAAATGAACTATCAATCCCAGGACTCCAACTTGCACATCTTTAGGTCAC.

(2) INFORMATION FOR SEQ ID NO: 664:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 55 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA80 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 664:

ACGGGCTGCTGGTGGGTGTGTTTGCATGACCACAGTGTGAGTCATGCATG TGTTT

(2) INFORMATION FOR SEQ ID NO: 665:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA ( enomic) ft±-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA80 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 665: TGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 666:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 47 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA80 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 666:

ATCATGACTCAAGTGCAGGTTTGAGTGGAGAAGGGGAAAGAAATGTG (2) INFORMATION FOR SEQ ID NO: 667:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 41 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA82 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 667: (2) INFORMATION FOR SEQ ID NO: 668:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA82 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 668: GTGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 669:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 61 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA82 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 669:

TTAAAGTGTATGATTACAGCTGTGTAATGACACAAAGCCAAAACAGCAAG GCACTACTGCT

(2) INFORMATION FOR SEQ ID NO: 670:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 43 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -mtr7v -

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA84 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 670:

GATCTTGATATCTGCGAATTACTCCTAAATAGTGCAAAACAAA (2) INFORMATION FOR SEQ ID NO: 671:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 17 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA84 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 671: TGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 672:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 117 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA84 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 672:

AATTACTGAGATGTTACTGGAATAGTGTCATGAATATTTGTGGGCCTTTC ACCTGGTTTTACTGATTGGTTGTTAATATTCTTCCTCTTTTGCTTCTTC. CTCCCTCTCTGCCTCTA (2) INFORMATION FOR SEQ ID NO: 673:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 36 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA85 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 673: GATCTTTGTTTTTTAGATGTTGAATTTTAAGCCAAC (2) INFORMATION FOR SEQ ID NO: 674:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 50 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA85 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 674:

ATATATATATATGTGTGTGTGTATGTGTGTATATATATTTATATATATAT (2) INFORMATION FOR SEQ ID NO: 675:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 73 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA85 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 675:

ACCTTCTGCATAGCATAGGGAACTCTACTCAGTATTTTGTAATAACTTAC AAGGAGAAAGAACCTGAAAAAGC

(2) INFORMATION FOR SEQ ID NO: 676:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 91 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA86 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 676:

GCCAGTAATACACCATCTCCCAGTTTGACAGGTGCAAGAAAAGAGATTTA AGTGATTTCCAGGGACCACAGAACAATTCTGTGACTATATA

(2) INFORMATION FOR SEQ ID NO: 677:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA86 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 677: TGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 678: -W-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA86 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 678: ACAGACAGCAAGCATCTG (2) INFORMATION FOR SEQ ID NO: 679:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 56 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA89 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 679:

TAGAGCTCCCTGTGTTATAACAGAAAGTTCTCATTAGTTATCTATTTTAT ACATTT

(2) INFORMATION FOR SEQ ID NO: 680:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 59 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: (A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA89 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 680:

TATATATATATATATAGTCTGTATATGTGTGTGTGTGTGTGTATATATAT ATATATATA

(2) INFORMATION FOR SEQ ID NO: 681:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 96 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA89 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 681:

TCGCAAAGAGTCGGACATGACTGAGTGACTTCACTTTCTTTCTTTCACTC CTGTATTGCAGGCAGACTCTTTACCAGCTGAGCCACTAGGGACAGC

(2) INFORMATION FOR SEQ ID NO: 682:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 122 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA9 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 682:

TTTGTACTTTATATGGAGAAAATAATTTTTTTGAGCAGGACTTCCTAAAT GCCCTGTGAAGCGAGGTATAAAAATTCGAACTTCATATTGTTTACAAAGC CAATTAATTTTACCATTCAGAA -4oι-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA9 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 683:

GTGTGTGTGTGTGTGTGTGTGTGTGTGTA(TG(TG(TG(TG(TG(TGT (2) INFORMATION FOR SEQ ID NO: 684:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 97 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA9 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 684:

GAATTTCCTCCTTACCTTTAGTAACTAGGGTGAGAATAGCTTTTTAAATT CCATCCTTGAACTCATTTTGCCCCAAACCCCTGGATTCCACCCCCTA

(2) INFORMATION FOR SEQ ID NO: 685:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO -•40Z-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA94 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 685:

CTTTTCTTTTTCGAATCTCTTCTAGGGATTGAGACTGTGATTTT (2) INFORMATION FOR SEQ ID NO: 686:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 37 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA94 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 686: GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG (2) INFORMATION FOR SEQ ID NO: 687:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 79 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA94 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 687:

TTGACAAGAGGACATCAAAACAGTGAAGGATGATTGCCAGTTGTTCTAAA AAAGAACAATAAATGTAAAGCACCTCTAC

(2) INFORMATION FOR SEQ ID NO: 688: - -W3-

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA98 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 688: GATCTGGAATTAGACTGGGAAAAAT (2) INFORMATION FOR SEQ ID NO: 689:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 27 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA98 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 689: TGTGTGTGTGTGTGTGTGTGTGTGTGT (2) INFORMATION FOR SEQ ID NO: 690:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 96 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -4o4-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA98 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 690:

GCTTCAGTTTCTTAGATATAGGCAGAACTCCATTTTAAATGGCATAATCA TACAGTCACATTTTGTTCCTCTGAAACATGACATCTACCAACAATA

(2) INFORMATION FOR SEQ ID NO: 691:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 29 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA99 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 691: GACTGATGTTCACATGATTAATAGCACAT (2) INFORMATION FOR SEQ ID NO: 692:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 38 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA99 (repeat)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 692: TGTGTGTGTGTGTGTGTGTGTGTGTATTCATTTTTTTT (2) INFORMATION FOR SEQ ID NO: 693:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 106 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA99 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 693:

AATAGAGTGCTGCGAAAACTAGCTCGATAGTGTGCCCAGAGTTTACAGAG AAATCAAACTTAGACACAAGTCAGAAGCCATAGACAGTGTGAAGAGAGTA GCACCG

(2) INFORMATION FOR SEQ ID NO: 694:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 28 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLB84 (up)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 694: GATCCTTGAGGAGCTTTGAATTCTCTGG (2) INFORMATION FOR SEQ ID NO: 695:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 48 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus vii IMMEDIATE SOURCE: (B) CLONE: TGLB84 (repeat) (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 695:

AAAAAAAATCTAGAATTTTGCATATATCTGCATTTTTTTTTTTTTTTT (2) INFORMATION FOR SEQ ID NO: 696:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 44 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLB84 (down)

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 696:

AAGGATATGTTTGAAGCTCAAATGAAATTTGAGACACCTGCCTC

_4o7-

(2) INFORMATION FOR SEQ ID NO: 697:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA13UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 697: GCTCGAATTCTTACTCTTCTGTTTC (2) INFORMATION FOR SEQ ID NO: 698:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA13DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 698: CCAGCACCATGGAAATTCTCAGTC (2) INFORMATION FOR SEQ ID NO: 699:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA206UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 699: CTGTTGTAATATTTAGACTCATAAG (2) INFORMATION FOR SEQ ID NO: 700:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA206DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 700: AAAGAAGGCTGTGTCCCAAGG (2) INFORMATION FOR SEQ ID NO: 701:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA209UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 701: ACAAAGAGACCTGGCTGCCAAATTC (2) INFORMATION FOR SEQ ID NO: 702: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA209DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 702: AGCTGCTTCTGCCCATCCCTTTATT (2) INFORMATION FOR SEQ ID NO: 703:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA215UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 703: TTAGGATAAGGACCAGGC (2) INFORMATION FOR SEQ ID NO: 704:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus _4«Ό-

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA215DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 704:

AGCTTTTCGTGGGAAAGT

(2) INFORMATION FOR SEQ ID NO: 705:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA217UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 705: GGTTGCCATTTCCTTCTCTAATGC (2) INFORMATION FOR SEQ ID NO: 706:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA217DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 706: TCCTGTTCCATGTTTAGTTTTATCG (2) INFORMATION FOR SEQ ID NO: 707:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA22UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 707: TCTGGAGGGTTCTGAGCTAAGAAC (2) INFORMATION FOR SEQ ID NO: 708:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA22DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 708: GAGTCTACTTCGTCACCTAATTCAT (2) INFORMATION FOR SEQ ID NO: 709:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA226UP1 -< -

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 709: CTAAAGAAATGCAGTGTTGTCAGCC (2) INFORMATION FOR SEQ ID NO: 710:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(Vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA226DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 710: CTTAACAAGCCATGCTGAATGGTCT (2) INFORMATION FOR SEQ ID NO: 711:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA234UP1

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 711: TTGCTTTAGATTTATTTATTCATTT (2) INFORMATION FOR SEQ ID NO: 712:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA234DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 712: TCCCCACCATTATACACAAAG (2) INFORMATION FOR SEQ ID NO: 713:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 19 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA254UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 713: GCTGCTTGGCACAGGCAAA (2) INFORMATION FOR SEQ ID NO: 714:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA254DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 714: GGATTAATTTCTGGACTCTG -414-

(2) INFORMATION FOR SEQ ID NO: 715:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA255UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 715: ATAATAATTCCTGATTTGCAGGGTT (2) INFORMATION FOR SEQ ID NO: 716:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA255DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 716: GAACGGAAGACCATTAAACACCT (2) INFORMATION FOR SEQ ID NO: 717:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO WO 92/13102

-415-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA258UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 717; AAAGCCATATTCCATCTCTGGTGG (2) INFORMATION FOR SEQ ID NO: 718:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA258DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 718: TTGAAATCCAGGACAATGACAGAAT (2) INFORMATION FOR SEQ ID NO: 719:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA260UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 719:

GGGTTAAGCATTTTGGACAAAATTC

(2) INFORMATION FOR SEQ ID NO: 720:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs (B) TYPE: nucleic acid

(C) STPΛNDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA260DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 720: TTGGACTTACCATTTCTCTGTAATT (2) INFORMATION FOR SEQ ID NO: 721:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA269UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 721: CTTTCAATGTATTTGCTTATTTGTT (2) INFORMATION FOR SEQ ID NO: 722:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic,

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE: -MIT-

(B) CLONE: AGLA269DN1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 722: GACACTAGTAGATTTGAAACCCA (2) INFORMATION FOR SEQ ID NO: 723:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO -

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA284UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 723: AGTTTCATAACTGTACAGCAGTCAT (2) INFORMATION FOR SEQ ID NO: 724:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA28 DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 724: TGACATTCAGAGGAGCACCAACAA (2) INFORMATION FOR SEQ ID NO: 725:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -Hte-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA285UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 725: AAGGCTTCCTGCCAATCCCATTAAA (2) INFORMATION FOR SEQ ID NO: 726:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA285DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 726: AGCACCCTTCTTGACCTGCAACAG (2) INFORMATION FOR SEQ ID NO: 727:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .MITI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA29UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 727: AGGAAGCCGAGTGAGATATGTAAGC (2) INFORMATION FOR SEQ ID NO: 728:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA29DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 728: TTACAGCCTGTGTGAATGTCCTCTA (2) INFORMATION FOR SEQ ID NO: 729:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA291UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 729: TTCTCTCAAATGATGAATATGCTTC (2) INFORMATION FOR SEQ ID NO: 730:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic (ii ) HYPOTHETICAL: NC _*4 θ -

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA291DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 730: GGACTATTCTATGCATGCCTCTC (2) INFORMATION FOR SEQ ID NO: 731:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA293UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 731: GAAACTCAACCCAAGACAACTCAAG (2) INFORMATION FOR SEQ ID NO: 732:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

( ii) IMMEDIATE SOURCE:

(B) CLONE: AGLA293DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NC: 732: ATGACTTTATTCTCCACCTAGCAGA (2) INFORMATION FOR SEQ ID NO: 733: — —

(i ) SEQUENCE CHARACTERISTICS :

(A) LENGTH : 25 base pairs

(B) TYPE : nucleic acid

(C) STRANDEDNESS : single

(D) TOPOLOGY : linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA8UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 733: AGTGATGCATCTTTTGAAACAAAAG (2) INFORMATION FOR SEQ ID NO: 734:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: AGLA8DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 734: TATAGAACATGGGGTCACAAAGAG (2) INFORMATION FOR SEQ ID NO: 735:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(i ) MOLECULE TYPE: DNA (genomic)

(in) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus - -M X-

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBFSHUP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 735:

GAAATAACTTAAACAGAAGTAACAA

(2) INFORMATION FOR SEQ ID NO: 736:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBFSHDN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 736: CTACATGGTTTGTACATAAGAAC (2) INFORMATION FOR SEQ ID NO: 737:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic.) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBIRBPUP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 73^": GA CACCTTCTATGCTTCCACT (2) INFORMATION FOR SEQ ID NO: 738:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single WO 92/13102 --^\ 2_>- PCT/US92/00340

(D) TOPOLOGY : linear (ii) MOLECULE TYPE : DNA (genomic) ( iii) HYPOTHETICAL : NO (iv) ANTI-SENSE : NO

(vi) ORIGINAL SOURCE :

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBIRBPDN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 738: GATACTATTGTTTGCTTTAGGTAAT (2) INFORMATION FOR SEQ ID NO: 739:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBKCASUP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 739: CAGTTACAAACATGTGGTGAGAATA (2) INFORMATION FOR SEQ ID NO: 740:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: GBKCASDN2 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 740: AGAGCTTTGACATACAATAGACAA (2) INFORMATION FOR SEQ ID NO: 741:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG1UP3

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 741: TGCATAACAAAGAAAAGTAGCTGAG (2) INFORMATION FOR SEQ ID NO: 742:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG1DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 742: TTAGTTTGTCCCTAGTGCTCTCATG (2) INFORMATION FOR SEQ ID NO: 743:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE : DNA (genomic _ f25-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13BUP3

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 743: GAGTGACTCACTTTCACCTATAATA (2) INFORMATION FOR SEQ ID NO: 744:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG13BDN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 744: CTTAGCATAACGTCCTCTAGATTCA (2) INFORMATION FOR SEQ ID NO: 745:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(Vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG3UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 745: GAATATCAAGAAGTTTACTACAGCC O 92/13102 ^ _{„ '} P

(2) INFORMATION FOR SEQ ID NO: 746:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG3DN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 746: CTCTATATTCAAGTTTGGTTGGATG (2) INFORMATION FOR SEQ ID NO: 747:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(i ) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv; ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG4BUP2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 747: GAGCAGCTTCTTTCTTTCTCATCTT (2) INFORMATION FOR SEQ ID NO: 748:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic (iii) HYPOTHETICAL: NC (iv; ANTI-SENSE: NO .

-42 -

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG4BDN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 748: GCTCTTGGAAGCTTATTGTATAAAG (2) INFORMATION FOR SEQ ID NO: 749:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG7UP3

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 749: TTCATTGCAGCACTATTTACAATAG (2) INFORMATION FOR SEQ ID NO: 750:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: MGTG7DN3

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 750:

TAAGTTCCCTGTATCATTTTTTGAA

(2) INFORMATION FOR SEQ ID NO: 751:

(i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 25 base pairs - 428-

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA10UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 751: CTAAATTTATCCCACTGTGGCTCTT (2) INFORMATION FOR SEQ ID NO: 752:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA10DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 752: CAATCTGCAGTAGCATACATCCTTG (2) INFORMATION FOR SEQ ID NO: 753:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus - 9-

(B) CLONE: TGLA111UP1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 753: ACAAAGAGTCAGACACAGCTGAG (2) INFORMATION FOR SEQ ID NO: 754:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA111DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 754: AATGTTCTACTAGTAACTGACACTG (2, INFORMATION FOR SEQ ID NO: 755:

(1) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

( i) MOLECULE TYPE: DNA (genomic (in) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(v i) IMMEDIATE SOURCE:

(B) CLONE: TGLA116UP1

(x ) SEQUENCE DESCRIPTION: SEQ ID NO: 755: GCACAGTAATAAGAGTGATGGCAGA (2, INFORMATION FOR SEQ ID NO: 756:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear - ^li3©-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA116DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 756: TGGAGAAGATTTGGCTGTGTACCCA (2) INFORMATION FOR SEQ ID NO: 757:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA117UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 757: TGTAATGCTTTCTCTGCGATTATCC (2) INFORMATION FOR SEQ ID NO: 758:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA117DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 758: TCTAATTTAAGTGTGCGTCCATGCA (2) INFORMATION FOR SEQ ID NO: 759:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA12UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 759: GAAATAGTTATCAAATTTGGTTCCA (2) INFORMATION FOR SEQ ID NO: 760:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA12DN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 760: AGCATCTACTACATGCATGTTT (2) INFORMATION FOR SEQ ID NO: 761:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA122UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 761: CCCTCCTCCAGGTAAATCAGC (2) INFORMATION FOR SEQ ID NO: 762:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA122DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 762: AATCACATGGCAAATAAGTACATAC (2) INFORMATION FOR SEQ ID NO: 763:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA123UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 763: AGGGCTCAGACTGCTACTAGACAAA (2) INFORMATION FOR SEQ ID NO: 764: -H33-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA123DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 764: CTGCTGGTGAGGTCTGGCTCTGG (2) INFORMATION FOR SEQ ID NO: 765:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA124UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 765: ATGGAAAAAGAGGACCAGTGAATG (2) INFORMATION FOR SEQ ID NO: 766:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus - 43-*4—

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA124DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 766:

TTATTTCTGTCTCTTCCTGTATAGG

(2) INFORMATION FOR SEQ ID NO: 767:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA125UP2

(xi) SEQUENCE DESCRIPTION:^' SEQ ID NO: 767: CTGTGTTTTCCTACAGTCCTCAT (2) INFORMATION FOR SEQ ID NO: 768:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA125DN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 768: TTGTTGAGACCTTCTGTGTGCAT (2) INFORMATION FOR SEQ ID NO: 769:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA126UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 769: CTAATTTAGAATGAGAGAGGCTTCT (2) INFORMATION FOR SEQ ID NO: 770:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA126DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 770: TTGGTCTCTATTCTCTGAATATTCC (2) INFORMATION FOR SEQ ID NO: 771:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA127UP1 - -3 -

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 771: CAATTGTGTGGTAGTTTGGACATTC (2) INFORMATION FOR SEQ ID NO: 772:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA127DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 772: ACACTATTGCAAAGGACCTCCAATT (2) INFORMATION FOR SEQ ID NO: 773:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA128UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 773: GCAAAGTGAGTCAGTTATGTAGACA (2) INFORMATION FOR SEQ ID NO: 774:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA128DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 774: GTTTCCAACCAGAGACAATGAATTC (2) INFORMATION FOR SEQ ID NO: 775:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA130UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 775: CCAACTGGCCAGTCATAATAAATTG (2) INFORMATION FOR SEQ ID NO: 776:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA130DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 776: GGGCCGCAAAGGGTTGGATGCA (2) INFORMATION FOR SEQ ID NO: 777:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA132UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 777: CCTTGGTTTCTAATTGTTTATTGCT (2) INFORMATION FOR SEQ ID NO: 778:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA132DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 778: TTGTTGTTCAGTTGCTAAGTCATGT (2) INFORMATION FOR SEQ ID NO: 779:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA134UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 779: GTAAACATTTGAGTCTTGGTAGGAC (2) INFORMATION FOR SEQ ID NO: 780:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA134DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 780: AGAGTTGGACATGACTGAAGTGACT (2) INFORMATION FOR SEQ ID NO: 781:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA137UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 781:

GTTGACTTGTTAATCACTGACAGCC

(2) INFORMATION FOR SEQ ID NO: 782:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs _ -

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA137DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 782: CCTTAGACACACGTGAAGTCCAC - (2) INFORMATION FOR SEQ ID NO: 783:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA142UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 783: AATGGAGTGTTTCTTTTCGCCCTCT (2) INFORMATION FOR SEQ ID NO: 784:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA142DN1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 784: AGCAGTCATGCTGAATCAATTAACT (2) INFORMATION FOR SEQ ID NO: 785:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA147UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 785: TGCTATGCATTTAACCAAGGATGTA (2) INFORMATION FOR SEQ ID NO: 786:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA147DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 786: CATCCTGGAAAAATGCAAAATAGGA (2) INFORMATION FOR SEQ ID NO: 787:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA15UP2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 787: TGAATGAACTAATGGCACAAAAT (2) INFORMATION FOR SEQ ID NO: 788:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA15DN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 788: GGTTCACAAAGAGTTGGACAT (2) INFORMATION FOR SEQ ID NO: 789:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA153UP2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 789: GGAGTGGGAGAAAGGCTCAAA (2) INFORMATION FOR SEQ ID NO: 790:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) ^' STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA153DN2

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 790: TGCTTTACAGTGTTGTGTTAGTTT (2) INFORMATION FOR SEQ ID NO: 791:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

( i) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA158UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 791: GGTCTCAATTTGTAAAGTGCACTGT (2) INFORMATION FOR SEQ ID NO: 792:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO - <W-

(iv) .ANTI-SENSE : NO

(vi) ORIGINS SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA158DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 792: CTCACACCAAGTTCACTTTTAACAG (2) INFORMATION FOR SEQ ID NO: 793:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA159UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 793: GCATCCAGGGAACAAATTACAAAC (2) INFORMATION FOR SEQ ID NO: 794:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA159DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 794: TTTATTTCGAATCTCTTGAGTACAG (2) INFORMATION FOR SEQ ID NO: 795: -MH5-

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA164UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 795: CTTGATGGAACTAAAACTAAAACTG (2) INFORMATION FOR SEQ ID NO: 796:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA164DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 796: CATGACTGAAGCAACTTAGCATG (2) INFORMATION FOR SEQ ID NO: 797:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A)* ORGANISM: Bos taurus _M <e-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA170UP1

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 797:

GTCCTTGTTGATTATGTTACACAT

(2) INFORMATION FOR SEQ ID NO: 798:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA170DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 798: AGTAAGGACCTGCTGTATAGCA (2) INFORMATION FOR SEQ ID NO: 799:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA176UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 799: AGTAGGAATACCCCAGGAGGAA (2) INFORMATION FOR SEQ ID NO: 800:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA176DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 800: TCAAGGCACAAGCACACAGTCA (2) INFORMATION FOR SEQ ID NO: 801:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA182UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 801: AAACGTTGGTTTCTTTTGGACTAT (2) INFORMATION FOR SEQ ID NO: 802:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA182DN1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 802: CCTCAGTGCTTCTTGCTTTAGA (2) INFORMATION FOR SEQ ID NO: 803:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA203UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 803: AATTGGGACTGAAGATGCCCTGG (2) INFORMATION FOR SEQ ID NO: 804:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA203DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 804: GAAGAGGAAAGCAGACTAGGACCT (2) INFORMATION FOR SEQ ID NO: 805:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) -<W-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA206UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 805: GAGAAGATATTTGCAAGCGTTACG (2) INFORMATION FOR SEQ ID NO: 806:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA206DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 806: AATTAGTAATGTCCAGCCCATTTAC (2) INFORMATION FOR SEQ ID NO: 807:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA210UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 807: ATGGTCTAGTGCTCTTCTTCCAGAA (2) INFORMATION FOR SEQ ID NO: 808:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA210DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 808: GGTTGCAAAGAGTCAGACAGGACT (2) INFORMATION FOR SEQ ID NO: 809:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA214UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 809: AGGCTTCTCTGTCCATGAAATG (2) INFORMATION FOR SEQ ID NO: 810:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO -45J -

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA214DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 810: AATGGTAAAGAATCAGCAAAGAGTC (2) INFORMATION FOR SEQ ID NO: 811:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA215UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 811: GCTAGGTGATGCACTTTATACACTT (2) INFORMATION FOR SEQ ID NO: 812:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA215DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 812:

CATACATAACTGAGTGACTGAGCAT

(2) INFORMATION FOR SEQ ID NO: 813:

(i) SEQUENCE CHARACTERISTICS: A LENGTH: 25 base airs (B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(Vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA22UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 813: TTGTCTTAAGCTTCAATTGCAAGTA (2) INFORMATION FOR SEQ ID NO: 814:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA22DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 814: GATTTGGACACAACTGAGCCACT (2) INFORMATION FOR SEQ ID NO: 815:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA227UP1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 815: CGAATTCCAAATCTGTTAATTTGCT (2) INFORMATION FOR SEQ ID NO: 816:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA227DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 816: ACAGACAGAAACTCAATGAAAGCA (2) INFORMATION FOR SEQ ID NO: 817:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA23UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 817: GAGACACAAGCTTTCAACCACC (2) INFORMATION FOR SEQ ID NO: 818:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA23DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 818: TGCCCCAGTTGATTTATTAAAAACA (2) INFORMATION FOR SEQ ID NO: 819:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA231UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 819: ATTTCCCTTTGGTTTGTAAAGACAG (2) INFORMATION FOR SEQ ID NO: 820:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA231DN1

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 820: m_ -lS5~

CTGCAAAGAGTTGGACAGAACTGA (2) INFORMATION FOR SEQ ID NO: 821:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA245UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 821: TCTATGTTCATCAGTGATATTGGCC (2) INFORMATION FOR SEQ ID NO: 822:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA245DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 822: AATTGCAGGTGAAAGAACACTTCAA (2) INFORMATION FOR SEQ ID NO: 823:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -4S< -

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA260UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 823: GATGGATTATTGACCTGTTCTGATT (2) INFORMATION FOR SEQ ID NO: 824:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: . single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA260DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 824: GCAGTGAGCAGTAGGAGCTTGG (2) INFORMATION FOR SEQ ID NO: 825:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA263UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 825: CAAGTGCTGGATACTATCTGAGCA (2) INFORMATION FOR SEQ ID NO: 826: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA263DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 826: TTAAAGCATCCTCACCTATATATGC (2) INFORMATION FOR SEQ ID NO: 827:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA28UP3

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 827: TGCTTCTGTAGGTTCTTAGACT (2) INFORMATION FOR SEQ ID NO: 828:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE: ANI M Bos r (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA28DN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 828:

GTCTCTG.AAGATGTTTGGCCTT

(2) INFORMATION FOR SEQ ID NO: 829:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA303UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 829: TAATCATAAGTCAAAGTAACAGTTT (2) INFORMATION FOR SEQ ID NO: 830:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA303DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 830: GATCTGGACATACAAAAGTATTAC (2) INFORMATION FOR SEQ ID NO: 831:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA304UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 831: GATCTGTCAACCTTTCAATTGATTC (2) INFORMATION FOR SEQ ID NO: 832:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA304DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 832: CTAGGTGTAGAACTGAGGAGGGT (2) INFORMATION FOR SEQ ID NO: 833:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA307UP1 -H- ø-

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 833: AGCAGACAAGGAAAGGTTACCATCC (2) INFORMATION FOR SEQ ID NO: 834:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA307DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 834: GTTAGGACTAGAAGGAGGCAGTCTG (2) INFORMATION FOR SEQ ID NO: 835:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA309UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 835: ACCTTTGTCCTTTGTATTCTGTGAA (2) INFORMATION FOR SEQ ID NO: 836:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA309DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 836: AGGAGGTCCATTTCAATATTATGAA (2) INFORMATION FOR SEQ ID NO: 837:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA322UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 837: CATGCCACCTCTTGTCTGAAA (2) INFORMATION FOR SEQ ID NO: 838:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA322DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 838: CTTTAACATGGTTTAAATGACTATT (2) INFORMATION FOR SEQ ID NO: 839:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA325UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 839: GGGCACTTTACTCTCTGAACAAATC (2) INFORMATION FOR SEQ ID NO: 840:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA325DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 840: GCTGACAGTCTATTTCCAGAAGGTA (2) INFORMATION FOR SEQ ID NO: 841:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE :

(A) ORGANISM : Bos taurus

(vii) IMMEDIATE SOURCE :

(B) CLONE: TGLA327UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 841: TCTGAAGGCTAAATAACTTCTCTAT (2) INFORMATION FOR SEQ ID NO: 842:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA327DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 842: GCACAAAGACTCAGACATGACTG (2) INFORMATION FOR SEQ ID NO: 843:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA328UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 843:

AAAGAAAGGCTGATATTGTAGCATC

(2) INFORMATION FOR SEQ ID NO: 844:

(i) SEQUENCE CHARACTERISTICS: A 'LENGTH: 25 base airs - *^ -

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA328DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 844: CTAACTGTGAGATTGCTTTGTAGTA (2) INFORMATION FOR SEQ ID NO: 845:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA334UP1

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 845: CGTCAGTGGAGAAATGGGATTCAA (2) INFORMATION FOR SEQ ID NO: 846:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA334DN1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 846: TCCCTCTTTGTATTGCTTGCAATAC (2) INFORMATION FOR SEQ ID NO: 847:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA337UP1

(Xi) SEQUENCE DESCRIPTION: SEQ ID NO: 847: TTTGTTAAGGATAGTAGGCTACT (2) INFORMATION FOR SEQ ID NO: 848:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA337DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 848: GCTCTTCCCTTGGTTTCCTTG (2) INFORMATION FOR SEQ ID NO: 849:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA339UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 849: GTTCTTGAATTCGGTCCCTACTTAA (2) INFORMATION FOR SEQ ID NO: 850:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA339DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 850: CGCAAGGAGTCAGACACAACTGA (2) INFORMATION FOR SEQ ID NO: 851:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA34UP2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 851: AATGGCTAAGCAGGCCAATCTAAGT (2) INFORMATION FOR SEQ ID NO: 852:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA34DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 852: GCTCAGCTTTCTTCACAGTCCAACT (2) INFORMATION FOR SEQ ID NO: 853:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA340UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 853: CAGGCCTTCACCAACAGTTCACTGA (2) INFORMATION FOR SEQ ID NO: 854:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .ANTI-SENSE : NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA340DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 854: GATTCCACAGTGCCAGACCAAAGCC (2) INFORMATION FOR SEQ ID NO: 855:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA341UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 855: GTATTTTCCATCCCAACAGTATGTT (2) INFORMATION FOR SEQ ID NO: 856:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA341DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 856: TACAGTTTCATGAGCCCTGTGGAT (2) INFORMATION FOR SEQ ID NO: 857: _ fc -

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA342UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 857: AGTGGCATTATTTCATTCTTTT (2) INFORMATION FOR SEQ ID NO: 858:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 19 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA342DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 858: CCTAAGACATGGAAGTGAC (2) INFORMATION FOR SEQ ID NO: 859:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA346UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 859:

CTTCTCTTAGGAATCATCTTGCTTT

(2) INFORMATION FOR SEQ ID NO: 860:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA346DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 860: TTTCTCTCATAACGACCCATGGAG (2) INFORMATION FOR SEQ ID NO: 861:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA35UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 861: TTAGCTGAATGGGGCATGGAAAGCA (2) INFORMATION FOR SEQ ID NO: 862:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA35DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 862: GAGCTGATGGAGGAAGCATGCACAT (2) INFORMATION FOR SEQ ID NO: 863:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA351UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 863: GCACATCTGGTGGCCACATCAG (2) INFORMATION FOR SEQ ID NO: 864:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA351DN1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 864: CTCTAGGGGATTTCAGTCTCAGT (2) INFORMATION FOR SEQ ID NO: 865:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(Vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA353UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 865: ATAGCCTTGGTTGGAAATTACTGAA (2) INFORMATION FOR SEQ ID NO: 866:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA353DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 866: AGAGTTTTCCTAACCCCAGAAAGTA (2) INFORMATION FOR SEQ ID NO: 867:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA354UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 867: TCCCAAATAGATCCTAAGGTCCTTG (2) INFORMATION FOR SEQ ID NO: 868:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA35 DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 868: AAATATAGAGATAGCCCATGTGCAG (2) INFORMATION FOR SEQ ID NO: 869:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA357UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 869: AAAAGGTTTGGGGTGTATGGG (2) INFORMATION FOR SEQ ID NO: 870:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

( i) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA357DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 870: TCTCCCTCTGTCTCATCTAAG (2) INFORMATION FOR SEQ ID NO: 871:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA36UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 871: GCTTCTCGTCACAAGGATGGTCC (2) INFORMATION FOR SEQ ID NO: 872:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE : DNA (genomic) (iii) HYPOTHETICAL : NO (iv) ANTI-SENSE : NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA36DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 872: TGCATGACTGAGCAATTAACACGTG (2) INFORMATION FOR SEQ ID NO: 873:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA37UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 873; CATTCCAATCCCCTATCCTGAG (2) INFORMATION FOR SEQ ID NO: 874:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA37DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 874:

TTGAATGATTCTATGAAGACCTGTA

(2) INFORMATION FOR SEQ ID NO: 875:

(i) SEQUENCE CHARACTERISTICS: A LENGTH: 24 base airs (B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA377UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 875: GACTGTCATTATCTTCCAGCGGAG (2) INFORMATION FOR SEQ ID NO: 876:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA377DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 876: AGACTTTGGATCTCTGGTTGAAATG (2) INFORMATION FOR SEQ ID NO: 877:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA378UP1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 877: TTTATAGCCAACCATATACTTTGCC (2) INFORMATION FOR SEQ ID NO: 878:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA378DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 878: CAGTACCTCTCAACTTCATGTATGT (2) INFORMATION FOR SEQ ID NO: 879:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA382UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 879: AACTAAGATCCCACAAGTCATGCAA (2) INFORMATION FOR SEQ ID NO: 880:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear - 70-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA382DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 880: GCAACTGGCACCACCATCTATCC (2) INFORMATION FOR SEQ ID NO: 881:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA387UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 881: CAAAGTCTTAGAATAAACTGGATGG (2) INFORMATION FOR SEQ ID NO: 882:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA387DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 882: GTCCCTTTGTTTACTTTGATAAAAC (2) INFORMATION FOR SEQ ID NO: 883:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA40UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 883: GCTTCTCTGCCAACTAATATTATCC (2) INFORMATION FOR SEQ ID NO: 884:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA40DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 884; CACCAGGTAAGCCCCTTATATATGT (2) INFORMATION FOR SEQ ID NO: 885:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA415UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 885: AAATCCTCCTCTGTTATCAATAGAG (2) INFORMATION FOR SEQ ID NO: 886:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA415DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 886: GGCTACACTTCATGCGGTCACAA (2) INFORMATION FOR SEQ ID NO: 887:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA420UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 887: TACTATGGTCTAGTGTCAAACAAAA (2) INFORMATION FOR SEQ ID NO: 888: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA420DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 888: AGCATCACTGTTTGAAAGCATCAAT (2) INFORMATION FOR SEQ ID NO: 889:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA421UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 889: GAGCAGCCCTTGGAGTCTATGTCCA (2) INFORMATION FOR SEQ ID NO: 890:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -462-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA421DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 890:

TCTCTGCCTCACACCCTCGTACTTG

(2) INFORMATION FOR SEQ ID NO: 891:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA423UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 891: CCAAAGCAGTGGTGTTAGATATAG (2) INFORMATION FOR SEQ ID NO: 892:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA423DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 892: GTCTTCTCTCAGAAATATATATTGC (2) INFORMATION FOR SEQ ID NO: 893:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid -4β3-

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA431UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 893: GGTCATATCCTTCAAAATTTACTTA (2) INFORMATION FOR SEQ ID NO: 894:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA431DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 894: CCCATTTATTCCTAATTTCAACTTC (2) INFORMATION FOR SEQ ID NO: 895:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA433UP1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 895: ATTTCTATGAAGTAGTCTTCTGACT (2) INFORMATION FOR SEQ ID NO: 896:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA433DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 896: ATTTTAAAACTAGTCACGAGTGCCT (2) INFORMATION FOR SEQ ID NO: 897:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA435UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 897: TCATTAATATTGGTCTGTAATTTCC (2) INFORMATION FOR SEQ ID NO: 898:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) -465-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA435DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 898: ACATTCAAACTCATTCTATGAGGC (2) INFORMATION FOR SEQ ID NO: 899:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA44UP2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 899: AACTGTATATTGAGAGCCTACCATG (2) INFORMATION FOR SEQ ID NO: 900:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA44DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 900: CACAACTTAGCGACTAAACCACCA - βto-

(2) INFORMATION FOR SEQ ID NO: 901:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA441UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 901: CAAGTCATCTGAATTTAATATACAG (2) INFORMATION FOR SEQ ID NO: 902:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA441DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 902: TTTCAATGTGTCTGCACTGGGT (2) INFORMATION FOR SEQ ID NO: 903:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO -4fc7-

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA444UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 903: CTCACAGCACAAAGCAGATGTTT (2) INFORMATION FOR SEQ ID NO: 904:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA444DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 904: TAGTGTTAGAGCAAAATTAATCTTC (2) INFORMATION FOR SEQ ID NO: 905:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA45UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 905:

TGCTTGTGGCAAGAAAGAGCTT

(2) INFORMATION FOR SEQ ID NO: 906:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base airs -466-

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA45DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 906: AGGCGAACGTGACATTAAGACT (2) INFORMATION FOR SEQ ID NO: 907:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA47UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 907: ATTCTTCTACTTCCTCAAGTGAAT (2) INFORMATION FOR SEQ ID NO: 908:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (B) CLONE: TGLA47DN1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 908: GAAATAGCAACCCAACCATATTAT (2) INFORMATION FOR SEQ ID NO: 909:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA48UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 909: AAATGTTTTATCTTGACTACTAAGC (2) INFORMATION FOR SEQ ID NO: 910:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA48DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 910: ACATGACTCTGCCATAGAGCAT (2) INFORMATION FOR SEQ ID NO: 911:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear -49o-

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA49UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 911: GGCAGGACTTCACTCTTTTTCA (2) INFORMATION FOR SEQ ID NO: 912:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA49DN2

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 912: AGAAAAGGAATAATGAGACAGATTA (2) INFORMATION FOR SEQ ID NO: 913:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(Vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA51UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 913: -49. -

TCTTTT.AAGGTTATCTGCCACCTAA (2) INFORMATION FOR SEQ ID NO: 914:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bo.s taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA51DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 914: GTCGCAGAGTCAGACGTGACTG (2) INFORMATION FOR SEQ ID NO: 915:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA52UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 915: GATTTCTGGTCTGTTTAGTGCTT (2) INFORMATION FOR SEQ ID NO: 916:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO -4^2-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA52DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 916: GCTTCCAAAACTTTACAATATGTAT (2) INFORMATION FOR SEQ ID NO: 917:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA53UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 917: GCTTTCAGAAATAGTTTGCATTCA (2) INFORMATION FOR SEQ ID NO: 918:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(Vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA53DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 918: ATCTTCACATGATATTACAGCAGA (2) INFORMATION FOR SEQ ID NO: 919: (i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA58UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 919: GTGCATGGACAATAATTCTACTCT (2) INFORMATION FOR SEQ ID NO: 920:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 21 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA58DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 920: GCAGTGTTGGCTCCAAGAGCA (2) INFORMATION FOR SEQ ID NO: 921:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus (vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA6UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 921:

TAGGCACAATGTCAATAATTTACTC

(2) INFORMATION FOR SEQ ID NO: 922:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA6DN1

( i) SEQUENCE DESCRIPTION: SEQ ID NO: 922: AATTCTCCATGTTAAGGGTTTACCA (2) INFORMATION FOR SEQ ID NO: 923:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60AUP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 923: AGTCCTCGAGGGTGAAGTAAGA (2) INFORMATION FOR SEQ ID NO: 924:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60ADN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 924: ATCTTTACCGTCTGAGCCACCA (2) INFORMATION FOR SEQ ID NO: 925:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60BUP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 925: GGATGACATTGTACATCATGAA (2) INFORMATION FOR SEQ ID NO: 926:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA60BDN1 -49< -

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 926: GATATAAAATTCTTAGTTGACAGT (2) INFORMATION FOR SEQ ID NO: 927:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE¹: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA61UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 927: CCTTGAAATAGTAAAAAGACCATAT (2) INFORMATION FOR SEQ ID NO: 928:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA61DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 928:

GGCAATCTGGATACCTGACATA

(2) INFORMATION FOR SEQ ID NO: 929:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) -4T7-

(iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA67UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 929: GTGTCAAGTAAGACTGTTCAAA (2) INFORMATION FOR SEQ ID NO: 930:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA67DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 930: TATGGAATTGCAAAGAATTGGAT (2) INFORMATION FOR SEQ ID NO: 931:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA68UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 931: ATCTTACTTACCTTCTCAGAGCT (2) INFORMATION FOR SEQ ID NO: 932:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA68DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 932: GGGACAAAATTTTACATATACACTT (2) INFORMATION FOR SEQ ID NO: 933:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 0 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA72UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 933:

(2) INFORMATION FOR SEQ ID NO: 934:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 0 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO (vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA72DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 934:

(2) INFORMATION FOR SEQ ID NO: 935:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 20 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA73UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 935: GAGAATCACCTAGAGAGGCA (2) INFORMATION FOR SEQ ID NO: 936:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA73DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 936:

CTTTCTCTTTAAATTCTATATGGT

(2) INFORMATION FOR SEQ ID NO: 937:

(i) SEQUENCE CHARACTERISTICS: A LENGTH: 25 base airs -5~00-

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA75UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 937: GATAGTTTAACTTGAGGAGATTGCC (2) INFORMATION FOR SEQ ID NO: 938:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA75DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 938: GACAAAACCAGGTAAATCTTTCTAC (2) INFORMATION FOR SEQ ID NO: 939:

(i) SEQUENCE CHi-iRACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -5Oι-

(B) CLONE: TGLA76UP1 (xi) SEQUENCE DESCRIPTION: SEQ ID NO: 939: GTCCAGTATTTCATTCTTTTTAAT (2) INFORMATION FOR SEQ ID NO: 940:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA76DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 940: ACAACCTAAATGTCCATCAGTA (2) INFORMATION FOR SEQ ID NO: 941:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 24 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA77UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 941: ATTGAATAAAAGACAGGAGATGCT (2) INFORMATION FOR SEQ ID NO: 942:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA77DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 942: ACGCATGAAGATGAGCTGCTAT (2) INFORMATION FOR SEQ ID NO: 943:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) .ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA80UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 943: GACCACAGTGTGAGTCATGCAT (2) INFORMATION FOR SEQ ID NO: 944:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA80DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 944: TGAGTGGAGAAGGGGAAAGAAAT (2) INFORMATION FOR SEQ ID NO: 945:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA82UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 945: ATCAATAACACTATTAAAGTATGCA (2) INFORMATION FOR SEQ ID NO: 946:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 23 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS : single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA82DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 946: AGTGTATGATTACAGCTGTGTAA (2) INFORMATION FOR SEQ ID NO: 947:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO 5O4-

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA86UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 947: CCCAGTTTGACAGGTGCA (2) INFORMATION FOR SEQ ID NO: 948:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 18 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: Single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA86DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 948: CAGACAGCAAGCATCTGC (2) INFORMATION FOR SEQ ID NO: 949:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA89UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 949: GTGTTATAACAGAAAGTTCTCATTA (2) INFORMATION FOR SEQ ID NO: 950: - 5 5~

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 22 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA89DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 950: TATTGCAGGCAGACTCTTTACC (2) INFORMATION FOR SEQ ID NO: 951:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic) (iii) HYPOTHETICAL: NO (iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA9UP1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 951: GAACTTCATATTGTTTAGAAAGCCA (2) INFORMATION FOR SEQ ID NO: 952:

(i) SEQUENCE CHARACTERISTICS:

(A) LENGTH: 25 base pairs

(B) TYPE: nucleic acid

(C) STRANDEDNESS: single

(D) TOPOLOGY: linear

(ii) MOLECULE TYPE: DNA (genomic)

(iii) HYPOTHETICAL: NO

(iv) ANTI-SENSE: NO

(vi) ORIGINAL SOURCE:

(A) ORGANISM: Bos taurus -5ϊ&-

(vii) IMMEDIATE SOURCE:

(B) CLONE: TGLA9DN1

(xi) SEQUENCE DESCRIPTION: SEQ ID NO: 952:

ACCTTTAGTAACTAGGGTGAGAATA

Claims

WHAT IS CLAIMED IS;

1. A set of nucleic acid fragments that hybridize to polymorphic loci in bovids, wherein said set com- prises fragments that hybridize to at least five unique loci and each fragment hybridizes to a locus comprising at least two alleles and with a hetero¬ zygosity of at least 50%.

2. The set of claim 1, wherein said polymorphic loci are selected from the group consisting of VNTR loci, multisite haplotype loci, microsatellite loci and combinations thereof.

3. The set of claim 2, wherein said polymorphic loci are VNTR loci.

4. The set of claim 3, wherein said fragments are selected from the group of VNTR markers identified in Table 1.

5. The set of claim 2, wherein said polymorphic loci are multisite haplotype loci.

6. The set of claim 5, wherein said fragments are selected from the group of multisite haplotype markers identified in Table 5.

7. The set of claim 2, wherein said polymorphic loci are microsatellite loci.

8. The set of claim 7, wherein said fragments are selected from the group of microsatellite markers identified in Table 7.

9. The set of claim 1, wherein said bovids are bovines. 10. The set of claim 9, wherein said bovines are of the species Bos taurus.

11. The set of claim 1, wherein said bovids are ovines.

12. The set of claim 1, wherein said fragments are obtained from a bovid genome.

13. The set of claim 12, wherein said bovid is a bovine.

14. The set of claim 13, wherein said bovine is of the species Bos taurus.

15. The set of claim 2, wherein said fragments are selected from the group of VNTR markers identified in Table 1, the group of multisite haplotype markers identified in Table 5, the group of micro¬ satellite markers identified in Table 7, and combinations thereof.

16. The set of claim 7, wherein said fragments are selected from the group of microsatellite markers identified in Table 8.

17. A synteny map of microsatellite markers identified in Table 9.

18. A synteny map of VNTR markers identified in Table 4.

19. The microsatellite marker TGLA116 for the Weaver condition.

20. The microsatellite marker TGLA116 for the QTL trait of enhanced milk production in Brown Swiss cattle. 21. A set of nucleic acid fragments comprising at least one fragment selected from the group consisting of the VNTR markers identified in Table 1, the multi¬ site haplotype markers identified in Table 5, and the microsatellite markers identified in Table 7.

22. A process for mapping quantitative traits in bovids which comprises using the set of claim 21.

23. A process for genetic identification using the set of claim 21.

24. A process for introducing a desired gene into a bovid which comprises using the set of claim 21.

25. The process of claim 21, which further comprises the use of velogenesis.