EP0350772A1 - Ampoule made of a synthetic material - Google Patents

Ampoule made of a synthetic material Download PDF

Info

Publication number
EP0350772A1
EP0350772A1 EP89112236A EP89112236A EP0350772A1 EP 0350772 A1 EP0350772 A1 EP 0350772A1 EP 89112236 A EP89112236 A EP 89112236A EP 89112236 A EP89112236 A EP 89112236A EP 0350772 A1 EP0350772 A1 EP 0350772A1
Authority
EP
European Patent Office
Prior art keywords
ampoule
constriction
head
diameter
adjoining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP89112236A
Other languages
German (de)
French (fr)
Inventor
Bernd Dipl.-Ing. Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0350772A1 publication Critical patent/EP0350772A1/en
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing

Definitions

  • the invention relates to an ampoule made of plastic with a molded ampoule head which can be separated from the ampoule body without tools and which is produced in the blowing process and filled in the blowing device and sealed by welding its head. is preferably greater than 5 mm.
  • the invention is therefore based on the object of creating an ampoule of the type mentioned at the outset, which makes it possible to realize larger opening diameters than hitherto. This object is achieved by an ampoule with the features of claim 1.
  • the former no longer needs to be rotated around the longitudinal axis of the ampoule body. Rather, it is sufficient to tilt the ampoule head to the side.
  • the wall is basically torn off due to the constriction.
  • the force required for tilting the ampoule head can also be applied well with a relatively large opening diameter, especially since one is not limited to grasping the ampoule head with two fingers. You can also load it with the palm of your hand, for example.
  • a clean edge is obtained. This may be due to the fact that the zone of reduced wall thickness is very narrow.
  • sections according to claim 4 adjoin the constriction on both sides.
  • the ampoule head preferably has the features of claims 5 and 8 to 10.
  • An ampoule 1 made of plastic aseptically manufactured in the blowing process and yet filled in the blowing device and sealed by welding in the area of its head has a cylindrical ampoule body 2 which is closed at one end by a base 3.
  • the ampoule body could also have a different cross-sectional shape, for example an elliptical shape. Its other end is formed by an also cylindrical, but reduced in diameter end portion 2 ', the wall thickness of which is equal to that of the rest of the ampoule body 2. Its outer diameter is only 50% of the outer diameter of the remaining part of the ampoule body 2.
  • the transition to the end section 2 ' is, as shown in FIGS. 1 and 2, conical.
  • the ampoule head 5 connects at the end section 2 'of the ampoule body 2 at the end section 2 'of the ampoule body 2 at the end section 2 'of the ampoule body 2 is followed by a constriction 4, to which in turn the ampoule head 5 connects.
  • the latter has the same outer diameter as the end section 2 'and is closed at the end facing away from the ampoule body 2 by a spherical shell-shaped material section.
  • the ampoule head 5 deviates from the cylindrical shape only to the extent that two troughs 6 of the same mirror-inverted design are provided at an axial distance from the constriction 4 for the engagement of the fingers that grip the ampoule head 5.
  • the troughs 6 have the shape of channels running transversely to the longitudinal direction of the ampoule 1.
  • the axial length of the ampoule head 5 is about two to three times as large as its outer diameter.
  • the constriction 4 as shown in FIGS. 1 and 2, has the shape of an annular groove with a wedge-shaped cross-sectional profile, as a result of which the base of the constriction 4 has an extremely small axial extent. Only in the area of this reason is the thickness of the wall reduced to a small value, namely to about 0.2-0.4 mm.
  • the two flanks of the constriction 4 enclose an angle of 45 °.
  • the angle between the flank on the side of the ampoule head 5 and a radial plane is 15 °, which results in a value of 30 ° for the angle between the other flank and the radial plane.
  • the inner diameter at the base of the constriction 4 is approximately 8 mm in the exemplary embodiment, which is why the torque that would be required to separate the ampoule head 5 from the ampoule body 2 by turning can no longer be applied by hand. Values larger than 0.8 mm can also be selected.
  • the ampoule head 5 is tilted to the side.
  • the ampoule head 5 can be grasped with the fingers. But it is also sufficient to push it aside, for example with the ball of your hand.
  • the axial length of the ampoule head 5 is completely sufficient to be able to apply the required force.
  • the tilting of the ampoule head 5, which is favored by the wedge shape of the cross-sectional profile of the constriction 4, has the consequence that plastic is torn off in the region of the bottom of the constriction 4, which defines the desired separation point becomes. This tearing off is possible since the zone of reduced wall thickness has a very small axial extent without fringe-like material parts being formed along the edge of the opening which is present after the ampoule head 5 has been separated.
  • the ampoule 1 can be produced and the contents introduced by one of the known methods.

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)

Abstract

In an ampoule (1) made of a synthetic material and with a moulded-on ampoule head (5) which can be separated from the ampoule body (2) without any tool, a cutting is made which provides the transition from the ampoule body (2) to the ampoule head (5) and which is in the form of a throat (4) tapering radially inwards in wedge formation. The base of this throat (4) forms the separation point. The reduced wall thickness is limited to the annular zone forming the separation point. <IMAGE>

Description

Die Erfindung betrifft eine im Blasverfahren hergestellte und in der Blasvorrichtung gefüllte sowie durch Verschweißen ihres Kopfes verschlossene Ampulle aus Kunststoff mit einem angeform­ten, ohne Werkzeuge vom Ampullenkörper trennbaren Ampullenkopf, wobei im Bereich der Trennstelle die Dicke der Wand reduziert und der Innnendurchmesser größer als 3 mm, vorzugsweise größer als 5 mm, ist.The invention relates to an ampoule made of plastic with a molded ampoule head which can be separated from the ampoule body without tools and which is produced in the blowing process and filled in the blowing device and sealed by welding its head. is preferably greater than 5 mm.

Bei bekannten, im Blasverfahren hergestellten und in der Blas­vorrichtung gefüllten und verschlossenen Ampullen ist zwischen dem Ampullenkopf und dem Ampullenkörper ein Abschnitt vorhanden, der bei der Herstellung der Ampulle sehr stark gereckt wird, um die Wandstärke so weit zu reduzieren, daß sie beim Drehen des Ampullenkopfes relativ zum Ampullenkörper im Bereich dieses Abschnittes abgerissen werden kann. Man spricht deshalb bei diesen Ampullen auch von solchen mit einem Twist-Off-Verschluß. Oberhalb eines Innendurchmessers der Trennstelle von etwa 3 mm treten bei diesen Ampullen Schwierigkeiten beim Öffnen auf. Zum einen erreicht das für das Abdrehen erforderliche Drehmoment einen Wert, der nicht mehr ohne weiteres aufge­bracht werden kann, wozu auch beiträgt, daß die Toleranzen der Wanddicke im Blasverfahren nicht entsprechend gering gehalten wer­den können. Zum anderen wird der Rand der entstehenden Öffnung infolge der Bildung von fransenartigen Materialpartien unsauber.In known ampoules produced in the blowing process and filled and sealed in the blowing device, a section is present between the ampoule head and the ampoule body, which is stretched very much during the manufacture of the ampoule in order to reduce the wall thickness to such an extent that when the ampoule head is turned can be torn off relative to the ampoule body in the area of this section. These ampoules are therefore also referred to as those with a twist-off closure. Above an inner diameter of the cutting point of about 3 mm, difficulties arise with these ampoules when opening. On the one hand, the torque required for turning off reaches a value that can no longer be applied easily, which also contributes to the fact that the tolerances of the wall thickness in the blowing process cannot be kept correspondingly low. On the other hand, the edge of the opening that is created becomes unclean due to the formation of fringe-like material parts.

Der Erfindung liegt daher die Aufgabe zugrunde, eine Ampulle der eingangs genannten Art zu schaffen, die es ermöglicht, größere Öffnungsdurchmesser als bisher realisieren zu können. Diese Aufgabe löst eine Ampulle mit den Merkmalen des Anspruches 1.The invention is therefore based on the object of creating an ampoule of the type mentioned at the outset, which makes it possible to realize larger opening diameters than hitherto. This object is achieved by an ampoule with the features of claim 1.

Zum Trennen des Ampullenkopfes vom Ampullenkörper braucht ersterer nicht mehr um die Längsaschse des Ampullenkörpers gedreht zu werden. Vielmehr genügt es, den Ampullenkopf zur Seite hin zu kippen. Dabei wird die Wand im Grunde der Einschnürung abgerissen. Der Kraftbedarf für das Kippen des Ampullenkopfes läßt sich auch bei relativ großem Öffnungsdurchmesser gut aufbringen, zumal man nicht darauf beschränkt ist, den Ampullenkopf mit zwei Fingern zu erfassen. Man kann ihn beispielsweise auch mit dem Handballen belasten. Ferner erhält man unabhängig vom Öffnungs­durchmesser, also auch bei relativ großen Öffnungs­durchmessern, einen sauberen Rand. Dies dürfte darauf zurückzuführen sein, daß die Zone reduzierter Wandstär­ke sehr schmal ist.To separate the ampoule head from the ampoule body, the former no longer needs to be rotated around the longitudinal axis of the ampoule body. Rather, it is sufficient to tilt the ampoule head to the side. The wall is basically torn off due to the constriction. The force required for tilting the ampoule head can also be applied well with a relatively large opening diameter, especially since one is not limited to grasping the ampoule head with two fingers. You can also load it with the palm of your hand, for example. Furthermore, regardless of the opening diameter, that is to say also with relatively large opening diameters, a clean edge is obtained. This may be due to the fact that the zone of reduced wall thickness is very narrow.

Bevorzugte Ausgestaltungen der Einschnürung sind Gegenstand der Ansprüche 2, 3, 6 und 7.Preferred configurations of the constriction are the subject of claims 2, 3, 6 and 7.

Bei einer bevorzugten Ausführungsform schließen sich beidseitig an die Einschnürung Abschnitte gemäß Anspruch 4 an.In a preferred embodiment, sections according to claim 4 adjoin the constriction on both sides.

Der Ampullenkopf weist vorzugweise die Merkmale der Ansprüche 5 und 8 bis 10 auf.The ampoule head preferably has the features of claims 5 and 8 to 10.

Die vorstehend und auch im nachfolgenden verwendete Bezeichnung "Ampulle" umfaßt alle flaschenartigen Behältnisse mit angeformtem Verschlußteil.The term “ampoule” used above and also in the following includes all bottle-like containers with a molded closure part.

Im folgenden ist die Erfindung anhand eines in der Zeichnung dargestellten Ausführungsbeispieles im einzelnen erläutert.The invention is explained in detail below using an exemplary embodiment shown in the drawing.

Es zeigen:

  • Fig. 1 eine Seitenansicht des Ausführungsbeispieles aus einer ersten Blickrichtung,
  • Fig. 2 eine Seitenansicht des Ausführungsbeispieles aus einer um 90 ° Umfangsrichtung versetzten Blickrichtung.
Show it:
  • 1 is a side view of the embodiment from a first viewing direction,
  • Fig. 2 is a side view of the embodiment from a viewing direction offset by 90 ° circumferential direction.

Eine aus Kunststoff bestehendeim Blasverfahren aseptisch hergestellte und dennoch in der Blasvorrichtung gefüllte und durch Verschweißen im Bereich ihres Kopfes verschlossene Am­pulle 1 weist einen zylindrischen Ampullenkörper 2 auf, der an seinem einen Ende durch einen Boden 3 verschlossen ist. Der Ampullenkörper könnte aber auch eine andere Querschnitts­form, beispielsweise eine elliptische Form, haben. Sein anderes Ende wird durch einen ebenfalls zylindrischen, im Durchmesser jedoch reduzierten Endabschnitt 2′ gebildet, dessen Wandstärke gleich derjenigen des übrigen Teils des Ampullenkörpers 2 ist. Sein Außendurchmesser beträgt aber nur 50 % des Außendurch­messers des übrigen Teils des Ampullenkörpers 2. Der Übergang zum Endabschnitt 2′ ist, wie die Fig. 1 und 2 zeigen, konisch ausgeführt.An ampoule 1 made of plastic aseptically manufactured in the blowing process and yet filled in the blowing device and sealed by welding in the area of its head has a cylindrical ampoule body 2 which is closed at one end by a base 3. The ampoule body could also have a different cross-sectional shape, for example an elliptical shape. Its other end is formed by an also cylindrical, but reduced in diameter end portion 2 ', the wall thickness of which is equal to that of the rest of the ampoule body 2. Its outer diameter is only 50% of the outer diameter of the remaining part of the ampoule body 2. The transition to the end section 2 'is, as shown in FIGS. 1 and 2, conical.

An den Endabschnitt 2′ des Ampullenkörpers 2 schließt sich eine Einschnürung 4 an, an die sich wiederum der Ampullenkopf 5 anschließt. Letzterer hat den gleichen Außendurchmesser wie der Endabschnitt 2′ und ist an dem dem Ampullenkörper 2 abge­kehrten Ende durch eine kugelschalenförmige Materialpartie verschlossen. Von der Zylinderform weicht der Ampullenkopf 5 nur in soweit ab, als in axialem Abstand von der Einschnürung 4 einander gegenüberliegend zwei spiegelbildlich gleich ausgebildete Mulden 6 für den Eingriff der den Ampullenkopf 5 erfassenden Finger vorgesehen sind. Es sind aber auch andere Querschnitts­formen geeignet. Die Mulden 6 haben die Form von quer zur Längs­richtung der Ampulle 1 verlaufenden Rinnen. In dieser Richtung erstrecken sich angeformte Rippen 7, die parallel und im Abstand nebeneinander angeordnet sind sowie über den Grund der Mulde 6 überstehen, um die beiden Mulden 6 griffiger zu machen. Die axiale Länge des Ampullenkopfes 5 ist etwa zwei- bis dreimal so groß wie ihr Außendurchmesser.At the end section 2 'of the ampoule body 2 is followed by a constriction 4, to which in turn the ampoule head 5 connects. The latter has the same outer diameter as the end section 2 'and is closed at the end facing away from the ampoule body 2 by a spherical shell-shaped material section. The ampoule head 5 deviates from the cylindrical shape only to the extent that two troughs 6 of the same mirror-inverted design are provided at an axial distance from the constriction 4 for the engagement of the fingers that grip the ampoule head 5. However, other cross-sectional shapes are also suitable. The troughs 6 have the shape of channels running transversely to the longitudinal direction of the ampoule 1. Molded ribs 7, which are arranged parallel and at a distance from one another, extend in this direction, as well project over the bottom of the trough 6 to make the two troughs 6 easier to grip. The axial length of the ampoule head 5 is about two to three times as large as its outer diameter.

Die Einschnürung 4 hat, wie die Fig. 1 und 2 zeigen, die Form einer Ringnut mit keilförmigem Querschnittsprofil, wodurch der Grund der Einschnürung 4 eine äußerst geringe axiale Er­streckung hat. Nur im Bereich dieses Grundes ist die Stärke der Wand auf einen geringen Wert reduziert, nämlich auf etwa 0,2 - 0,4 mm. Die beiden Flanken der Einschnürung 4 schließen im Ausführungsbeispiel einen Winkel von 45 ° ein. Dabei ist im Ausführungsbeispiel der Winkel zwischen der Flanke auf der Seite des Ampullenkopfes 5 und einer Radialebene 15 °, woraus sich für den Winkel zwischen der anderen Flanke und der Radial­ebene ein Wert von 30 ° ergibt. Es ist aber selbstverständlich auch möglich, beide Winkel gleich groß zu wählen oder den Winkel auf der Seite des Ampullenkopfes 5 größer als denjenigen auf der anderen Seite zu machen. Der Innendurchmesser am Grund der Einschnürung 4 beträgt im Ausführungsbeispiel etwa 8 mm, weshalb das Drehmoment, das nötig wäre, um den Ampullenkopf 5 durch Drehen vom Ampullenkörper 2 zu trennen, von Hand nicht mehr aufgebracht werden kann. Auch größere Werte als 0,8 mm können gewählt werden.The constriction 4, as shown in FIGS. 1 and 2, has the shape of an annular groove with a wedge-shaped cross-sectional profile, as a result of which the base of the constriction 4 has an extremely small axial extent. Only in the area of this reason is the thickness of the wall reduced to a small value, namely to about 0.2-0.4 mm. In the exemplary embodiment, the two flanks of the constriction 4 enclose an angle of 45 °. In the exemplary embodiment, the angle between the flank on the side of the ampoule head 5 and a radial plane is 15 °, which results in a value of 30 ° for the angle between the other flank and the radial plane. However, it is of course also possible to choose both angles of the same size or to make the angle on the side of the ampoule head 5 larger than that on the other side. The inner diameter at the base of the constriction 4 is approximately 8 mm in the exemplary embodiment, which is why the torque that would be required to separate the ampoule head 5 from the ampoule body 2 by turning can no longer be applied by hand. Values larger than 0.8 mm can also be selected.

Zum Öffnen der Ampulle 1 wird der Ampullenkopf 5 zur Seite hin gekippt. Der Ampullenkopf 5 kann dabei mit den Fingern erfaßt werden. Es genügt aber auch, ihn, beispielsweise mit dem Handballen, zur Seite zu drücken. Die axiale Länge des Ampullenkopfes 5 ist dabei völlig ausreichend, um die erforder­liche Kraft aufbringen zu können. Das Kippen des Ampullenkopfes 5, das durch die Keilform des Querschnittsprofils der Einschnü­rung 4 begünstigt wird, hat zur Folge, daß Kunststoff im Be­reich des Grundes der Einschnürung 4, welcher die Solltrenn­stelle dfiniert, abgerissen wird. Dieses Abreißen ist, da die Zone verminderter Wandstärke eine sehr geringe axiale Erstreckung hat, möglich, ohne daß dabei fransenartige Materialpartien längs des Öffnungsrandes entstehen, der nach dem Abtrennen des Ampullenkopfes 5 vorhanden ist.To open the ampoule 1, the ampoule head 5 is tilted to the side. The ampoule head 5 can be grasped with the fingers. But it is also sufficient to push it aside, for example with the ball of your hand. The axial length of the ampoule head 5 is completely sufficient to be able to apply the required force. The tilting of the ampoule head 5, which is favored by the wedge shape of the cross-sectional profile of the constriction 4, has the consequence that plastic is torn off in the region of the bottom of the constriction 4, which defines the desired separation point becomes. This tearing off is possible since the zone of reduced wall thickness has a very small axial extent without fringe-like material parts being formed along the edge of the opening which is present after the ampoule head 5 has been separated.

Wegen des relativ großen Innendurchmessers dieser Öffnung läßt sich nunmehr der Inhalt der Ampulle 1 dem Ampullenkörper 2 problemlos entnehmen.Because of the relatively large inner diameter of this opening, the contents of the ampoule 1 can now be easily removed from the ampoule body 2.

Die Herstellung der Ampulle 1 und das Einbringen des Inhaltes kann nach einem der bekannten Verfahren erfolgen.The ampoule 1 can be produced and the contents introduced by one of the known methods.

Alle in der vorstehenden Beschreibung erwähnten sowie auch die nur allein aus der Zeichnung entnehmbaren Merkmale sind als weitere Ausgestaltungen Bestandteile der Erfindung, auch wenn sie nicht besonders hervor­gehoben und insbesondere nicht in den Ansprüchen erwähnt sind.All of the features mentioned in the above description and also the features that can only be inferred from the drawing are further refinements of the invention, even if they are not particularly emphasized and in particular are not mentioned in the claims.

Claims (9)

1. Im Blasverfahren aseptisch hergestellt und in der Blasform gefüllte sowie durch Schweißen im Bereich des Kopfes ver­schlossene Ampulle aus Kunststoff mit einem angeformten, ohne Werkzeug vom Ampullenkörper trennbaren Ampullenkopf, wobei im Bereich der Trennstelle die Dicke der Wand reduziert und der Öffnungsdurchmesser größer als 3 mm, vorzugsweise größer als 5 mm, ist, dadurch gekennzeichnet, daß a) ein den Übergang vom Ampullenkörper (2) zum Ampullen­kopf (5) bildender Abschnitt in Form einer sich radial nach innen keilförmig verjüngenden Einschnürung (4) ausgebildet ist, b) der Grund dieser Einschnürung (4) die Trennstelle bildet, c) die verringerte Wandstärke auf die die Trennstelle bildende Ringzone beschränkt ist. 1. Aseptically manufactured in the blow molding process and filled in the blow mold and sealed by welding in the area of the head with a molded ampoule head, which can be separated from the ampoule body without tools, whereby the thickness of the wall is reduced in the area of the separation point and the opening diameter is greater than 3 mm , preferably greater than 5 mm, characterized in that a) a section forming the transition from the ampoule body (2) to the ampoule head (5) is designed in the form of a constriction (4) which tapers radially inwards, b) the reason of this constriction (4) forms the separation point, c) the reduced wall thickness is limited to the ring zone forming the separation point. 2. Ampulle nach Anspruch 1, dadurch gekennzeichnet, daß der Winkel, den die beiden Flanken der Einschnürung (4) ein­schließen, höchstens 90 °, vorzugsweise höchstens 75 °, beträgt.2. Ampoule according to claim 1, characterized in that the angle which the two flanks of the constriction (4) enclose is at most 90 °, preferably at most 75 °. 3. Ampulle nach Anspruch 2, dadurch gekennzeichnet, daß die eine Flanke der Einschnürung (4) mit einer Radialebene einen Winkel von 15 °, die andere einen Winkel von 30 ° einschließt.3. Ampoule according to claim 2, characterized in that the one flank of the constriction (4) with an radial plane includes an angle of 15 °, the other an angle of 30 °. 4. Ampulle nach einem der Ansprüche 1 bis 3, dadurch gekenn­zeichnet, daß die sich beidseitig an die Einschnürung (4) anschließenden Abschnitte (2′, 5) einen gleichen Durchmesser haben.4. ampoule according to one of claims 1 to 3, characterized in that the adjoining on both sides of the constriction (4) sections (2 ', 5) have the same diameter. 5. Ampulle nach Anspruch 4, dadurch gekennzeichnet, daß der Ampullenkopf (5) den gleichen Durchmesser wie der sich an die Einschnürung anschließende Abschnitt hat.5. Ampoule according to claim 4, characterized in that the ampoule head (5) has the same diameter as the section adjoining the constriction. 6. Ampulle nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, daß die Einschnürung (4) an ihrem Grund auf einen Durchmesser reduziert ist, der zwischen 50 % und 80 % des Durchmessers der sich anschließenden Abschnitte (2′, 5) beträgt und vorzugsweise bei 65 % liegt.6. Ampoule according to one of claims 1 to 5, characterized in that the constriction (4) is reduced at its bottom to a diameter which is between 50% and 80% of the diameter of the adjoining sections (2 ', 5) and is preferably 65%. 7. Ampulle nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, daß der sich an die Einschnürung (4) anschließende Abschnitt (2′, 5) einen Durchmesser hat, der höchstens um 60 %, vorzugsweise um etwa 50 %, kleiner ist als der Außendurchmesser des Ampullenkörpers (2).7. Ampoule according to one of claims 1 to 6, characterized in that the constriction (4) adjoining section (2 ', 5) has a diameter which is at most 60%, preferably about 50%, smaller than the outer diameter of the ampoule body (2). 8. Ampulle nach einem der Ansprüche 1 bis 7, dadurch gekennzeichnet, daß der Ampullenkopf einander gegenüberliegend je eine sich in Querrichtung erstreckende Mulde (6) aufweist.8. Ampoule according to one of claims 1 to 7, characterized in that the ampoule head opposite one another each has a transversely extending trough (6). 9. Ampulle nach Anspruch 8, dadurch gekennzeichnet, daß der Grund der Mulden (6) mit im Abstand nebenein­ander liegenden und sich in Querrichtung erstrecken­den, über den Muldengrund nach außen überstehenden Rippen (7) versehen ist.9. Ampoule according to claim 8, characterized in that the base of the troughs (6) is provided with spaced-apart and transversely extending ribs (7) projecting outwards beyond the base of the trough.
EP89112236A 1988-07-11 1989-07-05 Ampoule made of a synthetic material Ceased EP0350772A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19883823428 DE3823428A1 (en) 1988-07-11 1988-07-11 PLASTIC AMPOULE
DE3823428 1988-07-11

Publications (1)

Publication Number Publication Date
EP0350772A1 true EP0350772A1 (en) 1990-01-17

Family

ID=6358409

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89112236A Ceased EP0350772A1 (en) 1988-07-11 1989-07-05 Ampoule made of a synthetic material

Country Status (3)

Country Link
EP (1) EP0350772A1 (en)
JP (1) JP2825533B2 (en)
DE (1) DE3823428A1 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5046627A (en) * 1989-05-24 1991-09-10 Bernd Hansen Ampule
DE4408394A1 (en) * 1994-03-12 1995-09-21 Bernd Hansen Packaging for medical devices, such as contact lenses, in particular disposable contact lenses
EP0706406A1 (en) * 1993-07-02 1996-04-17 Barry Farris Method and apparatus for loading needleless syringes
WO1998025829A1 (en) * 1996-12-09 1998-06-18 Bausch & Lomb Incorporated Single-use flexible container
WO2000020055A1 (en) 1998-10-01 2000-04-13 Barry Farris Needleless system for transferring liquid from a container to a syringe without ambient air contamination
US6296150B1 (en) 1999-02-25 2001-10-02 Barry Farris Medicinal dosing apparatus and method
US6918418B1 (en) 2000-03-13 2005-07-19 Barry Farris Method and apparatus for the storage and transfer of a lyophilisate
EP3219305A1 (en) 2016-03-16 2017-09-20 Apostolos Georgopoulos Fosfomycin formulation for parenteral administration
EP4268805A1 (en) 2022-04-29 2023-11-01 Apostolos Georgopoulos Fosfomycin formulation for parenteral administration and method of manufacturing same

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59505300D1 (en) 1995-03-09 1999-04-15 Hansen Bernd Plastic bottle and process for its manufacture
DE19522451C2 (en) * 1995-06-21 1997-11-06 Bernd Hansen Device for dispensing a flowable substance from a container
DE19801320B4 (en) 1998-01-16 2004-08-26 Schott Glas Filled and sealed plastic container and process for its manufacture
DE102005038619A1 (en) 2005-08-16 2007-02-22 Pari GmbH Spezialisten für effektive Inhalation An inhalation therapy device with an ampoule for storing a medicament to be nebulised
JP4726593B2 (en) * 2005-09-28 2011-07-20 株式会社吉野工業所 Self-supporting bag
DE102007056462B4 (en) 2007-11-23 2011-10-27 Pari Pharma Gmbh Disposable ampoule for a device for generating aerosols
JP5452882B2 (en) * 2008-04-30 2014-03-26 株式会社吉野工業所 Resin ampoule
KR100932773B1 (en) * 2009-08-17 2009-12-21 피앤비팩(주) Plastic ampule
JP5897375B2 (en) * 2012-03-30 2016-03-30 株式会社吉野工業所 Ampoule container made of synthetic resin

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH528413A (en) * 1970-08-18 1972-09-30 Hartmann Emil Plastic container with twist lock
DE2140650A1 (en) * 1971-08-13 1973-02-22 Pmd Entwicklungswerk PLASTIC CONTAINER
US3749271A (en) * 1971-06-22 1973-07-31 Becton Dickinson Co Resealable ampoule closure
FR2257500A1 (en) * 1974-01-10 1975-08-08 Akerlund & Rausing Ab
DE3244403A1 (en) * 1982-12-01 1984-06-07 Hansen, Gerhard, 7166 Sulzbach-Laufen Container made from an elastic synthetic material
DE8808881U1 (en) * 1988-07-11 1988-08-25 Hansen, Bernd, Dipl.-Ing., 7166 Sulzbach-Laufen, De

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1921395U (en) * 1965-04-17 1965-08-12 Schwarzkopf Fa Hans SCREW CAP FOR PLASTIC BOTTLES.
JPS5211904B2 (en) * 1973-09-28 1977-04-02
GB1444848A (en) * 1974-08-29 1976-08-04 Barnes Hind Diagnostics Inc Plastics containers

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH528413A (en) * 1970-08-18 1972-09-30 Hartmann Emil Plastic container with twist lock
US3749271A (en) * 1971-06-22 1973-07-31 Becton Dickinson Co Resealable ampoule closure
DE2140650A1 (en) * 1971-08-13 1973-02-22 Pmd Entwicklungswerk PLASTIC CONTAINER
FR2257500A1 (en) * 1974-01-10 1975-08-08 Akerlund & Rausing Ab
DE3244403A1 (en) * 1982-12-01 1984-06-07 Hansen, Gerhard, 7166 Sulzbach-Laufen Container made from an elastic synthetic material
DE8808881U1 (en) * 1988-07-11 1988-08-25 Hansen, Bernd, Dipl.-Ing., 7166 Sulzbach-Laufen, De

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5046627A (en) * 1989-05-24 1991-09-10 Bernd Hansen Ampule
US6673050B1 (en) 1993-07-02 2004-01-06 Barry Farris Method and apparatus for loading syringes without the need for hypodermic needles
EP0706406A1 (en) * 1993-07-02 1996-04-17 Barry Farris Method and apparatus for loading needleless syringes
EP0706406A4 (en) * 1993-07-02 1997-01-08 Barry Farris Method and apparatus for loading needleless syringes
US6045538A (en) * 1993-07-02 2000-04-04 Farris; Barry Method and apparatus for loading syringes without the need for hypodermic needles
DE4408394A1 (en) * 1994-03-12 1995-09-21 Bernd Hansen Packaging for medical devices, such as contact lenses, in particular disposable contact lenses
EP0676333A1 (en) * 1994-03-12 1995-10-11 Hansen, Bernd, Dipl.-Ing. Packaging means for medical products such as contact lenses, in particular soft contact lenses
AU692819B2 (en) * 1994-03-12 1998-06-18 Bernd Hansen Package for medicinal products
DE4408394C2 (en) * 1994-03-12 1999-06-24 Bernd Hansen Packaging for contact lenses, in particular disposable contact lenses
WO1998025829A1 (en) * 1996-12-09 1998-06-18 Bausch & Lomb Incorporated Single-use flexible container
US6241124B1 (en) 1996-12-09 2001-06-05 Bausch & Lomb Incorporated Single-use container
US6308747B1 (en) 1998-10-01 2001-10-30 Barry Farris Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination
US6585134B2 (en) 1998-10-01 2003-07-01 Barry Farris Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination
WO2000020055A1 (en) 1998-10-01 2000-04-13 Barry Farris Needleless system for transferring liquid from a container to a syringe without ambient air contamination
US6296150B1 (en) 1999-02-25 2001-10-02 Barry Farris Medicinal dosing apparatus and method
US6547099B1 (en) 1999-02-25 2003-04-15 Barry Farris Medicinal dosing apparatus and method
US6918418B1 (en) 2000-03-13 2005-07-19 Barry Farris Method and apparatus for the storage and transfer of a lyophilisate
EP3219305A1 (en) 2016-03-16 2017-09-20 Apostolos Georgopoulos Fosfomycin formulation for parenteral administration
WO2017158099A1 (en) 2016-03-16 2017-09-21 Apostolos Georgopoulos Fosfomycin formulation for parenteral administration
EP3603618A1 (en) 2016-03-16 2020-02-05 Apostolos Georgopoulos Fosfomycin formulation for parenteral administration
EP4268805A1 (en) 2022-04-29 2023-11-01 Apostolos Georgopoulos Fosfomycin formulation for parenteral administration and method of manufacturing same

Also Published As

Publication number Publication date
DE3823428A1 (en) 1990-01-18
JP2825533B2 (en) 1998-11-18
JPH0265863A (en) 1990-03-06
DE3823428C2 (en) 1990-11-22

Similar Documents

Publication Publication Date Title
EP0350772A1 (en) Ampoule made of a synthetic material
DE1657154C3 (en) Axially printable cap closure for bottles and similar containers
DE3903354C1 (en)
DE3422546C2 (en) Container cap
AT398300B (en) TWO-PIECE DISPENSER CAP
DE1811695C3 (en) screw
DE2147566C2 (en) Closing stoppers of plastic, in particular for sparkling wine bottles
DE2759098A1 (en) MUG BOTTLE ARRANGEMENT
DE2842096A1 (en) HOSE COUPLING
EP0306665A2 (en) Discharging barrier, particularly for tubes, and its uses
CH653639A5 (en) ONE-PIECE HINGE PLASTIC.
DE3735909A1 (en) DRIP BOTTLE AND METHOD FOR THEIR PRODUCTION
CH669367A5 (en)
DE2512066A1 (en) SCREW CAP MADE OF PLASTIC OR AN APPROPRIATELY SOFT MATERIAL
DE1400838A1 (en) Fastener
CH655845A5 (en) DEVICE WITH A SCREW PIN FOR SCREWING INTO A TOOTH AND A TENSIONING DEVICE FOR HOLDING THE SCREW PIN.
DE2923379A1 (en) BOTTLE CAP
EP0354446B1 (en) Fixing device with an internal thread
CH637902A5 (en) CORKSCREW.
DE2854708A1 (en) DELIVERY CLOSURE
DE1475035B2 (en) Fastening device
DE1275448B (en) Closure arrangement for containers with a neck surrounding the opening and a closure cap
DE1942312C3 (en) Closure cap that can be applied by pressing axially onto the neck of a bottle
DE1500792A1 (en) Threaded fastening arrangement
EP0462390A2 (en) Multicomponent package

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19890705

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): DE FR GB IT

17Q First examination report despatched

Effective date: 19900821

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19920602

APAF Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNE