DE69942624D1 - Optisches Biopsiesystem - Google Patents

Optisches Biopsiesystem

Info

Publication number
DE69942624D1
DE69942624D1 DE69942624T DE69942624T DE69942624D1 DE 69942624 D1 DE69942624 D1 DE 69942624D1 DE 69942624 T DE69942624 T DE 69942624T DE 69942624 T DE69942624 T DE 69942624T DE 69942624 D1 DE69942624 D1 DE 69942624D1
Authority
DE
Germany
Prior art keywords
tissue
diagnosis
fluorescence
optical biopsy
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942624T
Other languages
English (en)
Inventor
Scott R Wilson
Chester E Sievert
Brian T Mcmahon
Ronald R Zimmermann
Robert A Palme
John G Yager
David R Walsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SpectraScience Inc
Original Assignee
SpectraScience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SpectraScience Inc filed Critical SpectraScience Inc
Application granted granted Critical
Publication of DE69942624D1 publication Critical patent/DE69942624D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/06Biopsy forceps, e.g. with cup-shaped jaws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/042Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by a proximal camera, e.g. a CCD camera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
DE69942624T 1998-03-09 1999-03-09 Optisches Biopsiesystem Expired - Lifetime DE69942624D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/037,722 US6174291B1 (en) 1998-03-09 1998-03-09 Optical biopsy system and methods for tissue diagnosis

Publications (1)

Publication Number Publication Date
DE69942624D1 true DE69942624D1 (de) 2010-09-02

Family

ID=21895938

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69939818T Expired - Lifetime DE69939818D1 (de) 1998-03-09 1999-03-09 Optisches biopsiesystem zur gewebediagnostik
DE69942624T Expired - Lifetime DE69942624D1 (de) 1998-03-09 1999-03-09 Optisches Biopsiesystem

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69939818T Expired - Lifetime DE69939818D1 (de) 1998-03-09 1999-03-09 Optisches biopsiesystem zur gewebediagnostik

Country Status (7)

Country Link
US (1) US6174291B1 (de)
EP (2) EP2018824B1 (de)
JP (2) JP4477230B2 (de)
AT (2) ATE474498T1 (de)
CA (1) CA2322768C (de)
DE (2) DE69939818D1 (de)
WO (1) WO1999045838A1 (de)

Families Citing this family (298)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7236815B2 (en) * 1995-03-14 2007-06-26 The Board Of Regents Of The University Of Texas System Method for probabilistically classifying tissue in vitro and in vivo using fluorescence spectroscopy
US20080146965A1 (en) * 2003-08-11 2008-06-19 Salvatore Privitera Surgical Device for The Collection of Soft Tissue
IL143258A0 (en) * 2001-05-20 2002-04-21 Given Imaging Ltd A method for in vivo imaging of the gastrointestinal tract in unmodified conditions
JP2001017379A (ja) * 1999-07-09 2001-01-23 Fuji Photo Film Co Ltd 蛍光診断装置
EP1089067B1 (de) * 1999-09-29 2004-12-08 Fuji Photo Film Co., Ltd. Vorrichtung zur Erfassung eines Fluoreszenzbildes
WO2001034031A1 (en) * 1999-11-05 2001-05-17 Spectrx, Inc. Multi-modal optical tissue diagnostic system
US8888688B2 (en) 2000-04-03 2014-11-18 Intuitive Surgical Operations, Inc. Connector device for a controllable instrument
US6858005B2 (en) 2000-04-03 2005-02-22 Neo Guide Systems, Inc. Tendon-driven endoscope and methods of insertion
US6610007B2 (en) 2000-04-03 2003-08-26 Neoguide Systems, Inc. Steerable segmented endoscope and method of insertion
US8517923B2 (en) * 2000-04-03 2013-08-27 Intuitive Surgical Operations, Inc. Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities
US6468203B2 (en) 2000-04-03 2002-10-22 Neoguide Systems, Inc. Steerable endoscope and improved method of insertion
EP1662972A4 (de) * 2000-04-03 2010-08-25 Intuitive Surgical Inc Aktivierte polymer-gelenkinstrumente und einführverfahren
US6984203B2 (en) * 2000-04-03 2006-01-10 Neoguide Systems, Inc. Endoscope with adjacently positioned guiding apparatus
US6678398B2 (en) * 2000-09-18 2004-01-13 Sti Medical Systems, Inc. Dual mode real-time screening and rapid full-area, selective-spectral, remote imaging and analysis device and process
ATE454845T1 (de) 2000-10-30 2010-01-15 Gen Hospital Corp Optische systeme zur gewebeanalyse
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
GB0030310D0 (en) * 2000-12-13 2001-01-24 Medical Res Council Apparatus and method for imaging a histological sample
JP3961765B2 (ja) * 2000-12-28 2007-08-22 ペンタックス株式会社 電子内視鏡システム
EP2333521B1 (de) 2001-04-30 2019-12-04 The General Hospital Corporation Verfahren und vorrichtung zur verbesserung der bildklarheit und empfindlichkeit bei der optischen kohärenz-tomographie unter verwendung von dynamischer rückkopplung zur kontrolle der fokussierungseigenschaften und der kohärenzsteuerung
DE10297689B4 (de) 2001-05-01 2007-10-18 The General Hospital Corp., Boston Verfahren und Gerät zur Bestimmung von atherosklerotischem Belag durch Messung von optischen Gewebeeigenschaften
US6814739B2 (en) 2001-05-18 2004-11-09 U.S. Endoscopy Group, Inc. Retrieval device
US6796710B2 (en) * 2001-06-08 2004-09-28 Ethicon Endo-Surgery, Inc. System and method of measuring and controlling temperature of optical fiber tip in a laser system
ATE404114T1 (de) * 2001-06-18 2008-08-15 Given Imaging Ltd Schluckbare in vivo-erfassungskapsel mit einer starre und flexible abschnitte aufweisenden leiterplatte
IL162696A0 (en) 2002-01-09 2005-11-20 Neoguide Systems Inc Apparatus and method for endoscopiccolectomy
US8423110B2 (en) * 2002-01-09 2013-04-16 Boston Scientific Scimed, Inc. Imaging device and related methods
CA2472197A1 (en) * 2002-01-09 2003-07-24 Neoguide Systems, Inc. Apparatus and method for spectroscopic examination of the colon
US7355716B2 (en) * 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US7769426B2 (en) * 2002-04-23 2010-08-03 Ethicon Endo-Surgery, Inc. Method for using an MRI compatible biopsy device with detachable probe
US7826883B2 (en) * 2002-04-23 2010-11-02 Devicor Medical Products, Inc. Localization mechanism for an MRI compatible biopsy device
US20030199753A1 (en) * 2002-04-23 2003-10-23 Ethicon Endo-Surgery MRI compatible biopsy device with detachable probe
US20110201924A1 (en) * 2002-04-30 2011-08-18 The General Hospital Corporation Method and Apparatus for Improving Image Clarity and Sensitivity in Optical Tomography Using Dynamic Feedback to Control Focal Properties and Coherence Gating
US7662094B2 (en) * 2002-05-14 2010-02-16 Given Imaging Ltd. Optical head assembly with dome, and device for use thereof
WO2004014227A1 (en) * 2002-08-13 2004-02-19 Given Imaging Ltd. System for in vivo sampling and analysis
US20040064053A1 (en) * 2002-09-30 2004-04-01 Chang Sung K. Diagnostic fluorescence and reflectance
US7662093B2 (en) * 2002-09-30 2010-02-16 Given Imaging, Ltd. Reduced size imaging device
AU2003269438A1 (en) * 2002-09-30 2004-04-19 Given Imaging Ltd. In-vivo sensing system
DE10246521B4 (de) * 2002-10-05 2005-11-10 Karl Storz Gmbh & Co. Kg Endoskop
JP4746876B2 (ja) * 2002-10-15 2011-08-10 ギブン イメージング リミテッド 移動装置に信号を転送するための装置、システムおよび方法
US7438692B2 (en) * 2002-10-18 2008-10-21 Mark Tsonton Localization mechanism for an MRI compatible biopsy device
US20080045788A1 (en) * 2002-11-27 2008-02-21 Zvika Gilad Method and device of imaging with an in vivo imager
US6980573B2 (en) * 2002-12-09 2005-12-27 Infraredx, Inc. Tunable spectroscopic source with power stability and method of operation
JP2006512130A (ja) * 2002-12-26 2006-04-13 ギブン・イメージング・リミテツド 不動化可能な生体内センシング装置
WO2004059568A1 (en) * 2002-12-26 2004-07-15 Given Imaging Ltd. In vivo imaging device and method of manufacture thereof
US8054468B2 (en) 2003-01-24 2011-11-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
CN1741768A (zh) 2003-01-24 2006-03-01 通用医疗有限公司 利用低相干干涉测量法识别组织的系统和方法
US6912050B2 (en) * 2003-02-03 2005-06-28 Hach Company Phase shift measurement for luminescent light
US8882657B2 (en) 2003-03-07 2014-11-11 Intuitive Surgical Operations, Inc. Instrument having radio frequency identification systems and methods for use
EP1611470B1 (de) 2003-03-31 2015-10-14 The General Hospital Corporation Speckle-reduktion bei der optischen kohärenztomographie durch weglängencodierte winkelzusammensetzung
US7102758B2 (en) 2003-05-06 2006-09-05 Duke University Fourier domain low-coherence interferometry for light scattering spectroscopy apparatus and method
EP2011434A3 (de) 2003-06-06 2009-03-25 The General Hospital Corporation Verfahren und Vorrichtung für eine Lichtquelle mit Abstimmung der Wellenlänge
US20040267121A1 (en) * 2003-06-12 2004-12-30 Sarvazyan Armen P. Device and method for biopsy guidance using a tactile breast imager
JP4306380B2 (ja) * 2003-09-10 2009-07-29 株式会社日立メディコ 医用画像表示方法及び装置
US20050059894A1 (en) * 2003-09-16 2005-03-17 Haishan Zeng Automated endoscopy device, diagnostic method, and uses
US7908690B2 (en) * 2003-09-30 2011-03-22 Sentinelle Medical, Inc. Supine patient support for medical imaging
US7970452B2 (en) * 2003-09-30 2011-06-28 Hologic, Inc. Open architecture imaging apparatus and coil system for magnetic resonance imaging
US20080077005A1 (en) * 2004-08-12 2008-03-27 Piron Cameron A System and Method for Multimodality Breast Imaging
US7379769B2 (en) * 2003-09-30 2008-05-27 Sunnybrook Health Sciences Center Hybrid imaging method to monitor medical device delivery and patient support for use in the method
EP2278287B1 (de) 2003-10-27 2016-09-07 The General Hospital Corporation Optische Abbildungsmethode und - vorrichtung mit Frequenzbereichsinterferometrie
WO2005054780A1 (en) * 2003-11-28 2005-06-16 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
US8326404B2 (en) * 2003-11-28 2012-12-04 British Columbia Cancer Agency Branch Multimodal detection of tissue abnormalities based on raman and background fluorescence spectroscopy
US20050171436A1 (en) * 2004-01-09 2005-08-04 Clarke Richard H. Raman spectroscopy for monitoring drug-eluting medical devices
ES2409160T3 (es) 2004-03-23 2013-06-25 Boston Scientific Limited Sistema de visualización in vivo
US7922654B2 (en) * 2004-08-09 2011-04-12 Boston Scientific Scimed, Inc. Fiber optic imaging catheter
US11819192B2 (en) 2004-03-23 2023-11-21 Boston Scientific Scimed, Inc. In-vivo visualization system
US20060155178A1 (en) * 2004-03-26 2006-07-13 Vadim Backman Multi-dimensional elastic light scattering
US7697576B2 (en) 2004-05-05 2010-04-13 Chem Image Corporation Cytological analysis by raman spectroscopic imaging
US20060281068A1 (en) * 2005-06-09 2006-12-14 Chemimage Corp. Cytological methods for detecting a disease condition such as malignancy by Raman spectroscopic imaging
US20050250091A1 (en) * 2004-05-05 2005-11-10 Chemlmage Corporation Raman molecular imaging for detection of bladder cancer
US9638770B2 (en) * 2004-05-21 2017-05-02 Devicor Medical Products, Inc. MRI biopsy apparatus incorporating an imageable penetrating portion
US7708751B2 (en) * 2004-05-21 2010-05-04 Ethicon Endo-Surgery, Inc. MRI biopsy device
US8932233B2 (en) 2004-05-21 2015-01-13 Devicor Medical Products, Inc. MRI biopsy device
JP4750786B2 (ja) 2004-05-29 2011-08-17 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィ(oct)イメージングにおける屈折層を用いた色分散補償プロセス、システム及びソフトウェア構成
WO2005122878A1 (en) * 2004-06-15 2005-12-29 Umc Utrecht Holding B.V. Method and device for the detection of cancer
WO2006005075A2 (en) * 2004-06-30 2006-01-12 Amir Belson Apparatus and methods for capsule endoscopy of the esophagus
US20060015013A1 (en) * 2004-06-30 2006-01-19 Zvika Gilad Device and method for in vivo illumination
US7596403B2 (en) 2004-06-30 2009-09-29 Given Imaging Ltd. System and method for determining path lengths through a body lumen
US7643865B2 (en) * 2004-06-30 2010-01-05 Given Imaging Ltd. Autonomous in-vivo device
US7447408B2 (en) * 2004-07-02 2008-11-04 The General Hospital Corproation Imaging system and related techniques
EP1782020B1 (de) 2004-08-06 2012-10-03 The General Hospital Corporation Prozess, system und softwareanordnung zur bestimmung mindestens einer position in einer probe unter verwendung von optischer kohärenztomographie
JP5324095B2 (ja) * 2004-08-24 2013-10-23 ザ ジェネラル ホスピタル コーポレイション 血管セグメントを画像化する方法および装置
WO2006024014A2 (en) * 2004-08-24 2006-03-02 The General Hospital Corporation Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample
KR101269455B1 (ko) 2004-09-10 2013-05-30 더 제너럴 하스피탈 코포레이션 광 간섭 영상화를 위한 시스템 및 방법
US7366376B2 (en) * 2004-09-29 2008-04-29 The General Hospital Corporation System and method for optical coherence imaging
MX2007003777A (es) * 2004-09-30 2007-05-24 Zila Biotechnology Inc Metodo de luz dirigida para detectar y ayudar en la evaluacon adicional de tejido mucoso anormal.
EP1799094A2 (de) * 2004-09-30 2007-06-27 Boston Scientific Scimed, Inc. Multifunktionales endoskopsystem zur verwendung in elektrochirurgischen anwendungen
US20080007734A1 (en) * 2004-10-29 2008-01-10 The General Hospital Corporation System and method for providing Jones matrix-based analysis to determine non-depolarizing polarization parameters using polarization-sensitive optical coherence tomography
AU2005229684A1 (en) * 2004-11-04 2006-05-18 Given Imaging Ltd Apparatus and method for receiving device selection and combining
US7417740B2 (en) * 2004-11-12 2008-08-26 Medeikon Corporation Single trace multi-channel low coherence interferometric sensor
EP1827281A1 (de) * 2004-11-17 2007-09-05 Biosense Webster, Inc. Gerät für die echtzeitbewertung der gewebeablation
US10413188B2 (en) * 2004-11-17 2019-09-17 Lawrence Livermore National Security, Llc Assessment of tissue or lesion depth using temporally resolved light scattering spectroscopy
US20060229515A1 (en) * 2004-11-17 2006-10-12 The Regents Of The University Of California Fiber optic evaluation of tissue modification
US7995210B2 (en) 2004-11-24 2011-08-09 The General Hospital Corporation Devices and arrangements for performing coherence range imaging using a common path interferometer
US8922781B2 (en) 2004-11-29 2014-12-30 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
US7854705B2 (en) * 2004-12-16 2010-12-21 Olga Pawluczyk Ex vivo verification of biopsy tissue samples
JP4619803B2 (ja) 2005-01-26 2011-01-26 富士フイルム株式会社 蛍光断層画像取得装置
US7688440B2 (en) 2005-01-27 2010-03-30 Prescient Medical, Inc. Raman spectroscopic test strip systems
US7524671B2 (en) * 2005-01-27 2009-04-28 Prescient Medical, Inc. Handheld raman blood analyzer
US7651851B2 (en) * 2005-01-27 2010-01-26 Prescient Medical, Inc. Handheld Raman body fluid analyzer
US20060241385A1 (en) * 2005-04-12 2006-10-26 Ethicon Endo-Surgery, Inc. Guided disposable fiducial for breast biopsy localization fixture
US20060235457A1 (en) * 2005-04-15 2006-10-19 Amir Belson Instruments having a rigidizable external working channel
EP1868485B1 (de) 2005-04-15 2016-06-08 Surgisense Corporation Chirurgische instrumente mit sensoren zur erkennung von gewebeeigenschaften sowie systeme zur verwendung solcher instrumente
JP2008538612A (ja) * 2005-04-22 2008-10-30 ザ ジェネラル ホスピタル コーポレイション スペクトルドメイン偏光感受型光コヒーレンストモグラフィを提供することの可能な構成、システム、及び方法
JP5684452B2 (ja) * 2005-04-28 2015-03-11 ザ ジェネラル ホスピタル コーポレイション 光干渉測定法により解剖学的構造に関連する情報を評価するためのシステム、方法及びソフトウエア装置
WO2006119166A2 (en) 2005-04-29 2006-11-09 The Regents Of The University Of Colorado Multi-excitation diagnostic systems and methods for classification of tissue
WO2006124860A1 (en) * 2005-05-13 2006-11-23 The General Hospital Corporation Arrangements, systems and methods capable of providing spectral-domain optical coherence reflectometry for a sensitive detection of chemical and biological sample
JP2008542758A (ja) * 2005-05-31 2008-11-27 ザ ジェネラル ホスピタル コーポレイション スペクトルコード化ヘテロダイン干渉法を画像化に使用可能なシステム、方法、及び装置
US8253936B2 (en) * 2008-08-08 2012-08-28 Chemimage Corporation Raman characterization of transplant tissue
KR101387454B1 (ko) * 2005-08-09 2014-04-22 더 제너럴 하스피탈 코포레이션 광간섭 단층촬영법에서 편광 기반 직교 복조를 수행하기위한 장치, 방법 및 저장 매체
US20070049833A1 (en) * 2005-08-16 2007-03-01 The General Hospital Corporation Arrangements and methods for imaging in vessels
WO2007033379A2 (en) * 2005-09-14 2007-03-22 Neoguide Systems, Inc. Methods and apparatus for performing transluminal and other procedures
US7872759B2 (en) 2005-09-29 2011-01-18 The General Hospital Corporation Arrangements and methods for providing multimodality microscopic imaging of one or more biological structures
EP2950065A1 (de) * 2005-10-11 2015-12-02 Duke University Verfahren zur endoskopischen winkelaufgelösten interferometrie mit niedriger kohärenz
US8537366B2 (en) 2005-10-11 2013-09-17 Duke University Systems and methods for endoscopic angle-resolved low coherence interferometry
US7889348B2 (en) * 2005-10-14 2011-02-15 The General Hospital Corporation Arrangements and methods for facilitating photoluminescence imaging
US7901441B2 (en) 2005-10-18 2011-03-08 Boston Scientific Scimed, Inc. Method of using an imaging catheter to conduct photodynamic procedures
EP1948056A2 (de) * 2005-10-24 2008-07-30 Spectrascience, Inc. System und verfahren für den nicht-endoskopischen optischen biopsie-nachweis von erkranktem gewebe
US9314164B2 (en) 2005-10-27 2016-04-19 Northwestern University Method of using the detection of early increase in microvascular blood content to distinguish between adenomatous and hyperplastic polyps
US20090203977A1 (en) * 2005-10-27 2009-08-13 Vadim Backman Method of screening for cancer using parameters obtained by the detection of early increase in microvascular blood content
EP1956962B1 (de) 2005-11-22 2020-09-16 Intuitive Surgical Operations, Inc. Systeme zur bestimmung der form eines biegbaren instruments
US7896805B2 (en) * 2005-11-23 2011-03-01 Given Imaging Ltd. In-vivo imaging device and optical system thereof
JP2009517608A (ja) * 2005-11-23 2009-04-30 ネオガイド システムズ, インコーポレイテッド 操舵可能な装置用の非金属マルチストランド制御ケーブル
US20080312502A1 (en) * 2005-12-02 2008-12-18 Christopher Paul Swain System and Device for in Vivo Procedures
US20070156051A1 (en) * 2005-12-29 2007-07-05 Amit Pascal Device and method for in-vivo illumination
US9320417B2 (en) 2005-12-29 2016-04-26 Given Imaging Ltd. In-vivo optical imaging device with backscatter blocking
US20070167834A1 (en) * 2005-12-29 2007-07-19 Amit Pascal In-vivo imaging optical device and method
EP1971848B1 (de) 2006-01-10 2019-12-04 The General Hospital Corporation Systeme und verfahren zur datengenerierung auf der basis eines oder mehrerer spektral kodierter endoskopieverfahren
WO2007084995A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Methods and systems for optical imaging of epithelial luminal organs by beam scanning thereof
WO2007084945A1 (en) * 2006-01-19 2007-07-26 The General Hospital Corporation Systems and methods for performing rapid fluorescense lifetime, excitation and emission spectral measurements
WO2007084903A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements
US20070171430A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and methods for providing mirror tunnel micropscopy
EP1973467B1 (de) * 2006-01-20 2013-10-16 The General Hospital Corporation Systeme und Verfahren zur Bereitstellung von Speckle-Reduktion über eine Wellenfront -Modulation zur optischen Kohärenzentomographie
US20070171433A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and processes for providing endogenous molecular imaging with mid-infrared light
US7418169B2 (en) * 2006-02-01 2008-08-26 The General Hospital Corporation Apparatus for controlling at least one of at least two sections of at least one fiber
US10426548B2 (en) * 2006-02-01 2019-10-01 The General Hosppital Corporation Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
WO2007149603A2 (en) * 2006-02-01 2007-12-27 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
WO2007092911A2 (en) 2006-02-08 2007-08-16 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
WO2007101026A2 (en) 2006-02-24 2007-09-07 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
WO2007103721A2 (en) * 2006-03-01 2007-09-13 The General Hospital Corporation System and method for providing cell specific laser therapy of atherosclerotic plaques by targeting light absorbers in macrophages
US20070239033A1 (en) * 2006-03-17 2007-10-11 The General Hospital Corporation Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry
WO2007118129A1 (en) * 2006-04-05 2007-10-18 The General Hospital Corporation Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
EP3150110B1 (de) 2006-05-10 2020-09-02 The General Hospital Corporation Verfahren, anordnungen und systeme zur bereitstellung von frequenzbereichsabbildung einer probe
WO2007133964A2 (en) * 2006-05-12 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
US8568299B2 (en) * 2006-05-19 2013-10-29 Intuitive Surgical Operations, Inc. Methods and apparatus for displaying three-dimensional orientation of a steerable distal tip of an endoscope
JP2009543663A (ja) * 2006-07-18 2009-12-10 トラスティーズ オブ ボストン ユニバーシティ 一体型マルチファイバ光プローブを有する装置および使用方法
CA2658481A1 (en) * 2006-07-21 2008-01-24 Oncoscope, Inc. Protective probe tip, particularly for use on a fiber-optic probe used in an endoscopic application
US20100165335A1 (en) * 2006-08-01 2010-07-01 The General Hospital Corporation Systems and methods for receiving and/or analyzing information associated with electro-magnetic radiation
FR2904927B1 (fr) * 2006-08-17 2018-05-18 Mauna Kea Technologies Utilisation d'un systeme d'imagerie par fluorescence confocale fibre in vivo in situ, systeme et procede d'imagerie par fluorescence confocale fibres in vivo in situ
EP3006920A3 (de) * 2006-08-25 2016-08-03 The General Hospital Corporation Vorrichtungen und verfahren zur verstärkung von optischer kohärenztomografiebildgebung mithilfe volumetrischer filterungsverfahren
US20080287808A1 (en) * 2006-09-12 2008-11-20 The General Hospital Corporation Apparatus, probe and method for providing depth assessment in an anatomical structure
US8838213B2 (en) * 2006-10-19 2014-09-16 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s)
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
JP5507258B2 (ja) 2007-01-19 2014-05-28 ザ ジェネラル ホスピタル コーポレイション 光周波数領域イメージングにおける測定深度を制御するための装置及び方法
US7949019B2 (en) * 2007-01-19 2011-05-24 The General Hospital Wavelength tuning source based on a rotatable reflector
US8396539B2 (en) * 2007-02-16 2013-03-12 Medtronic, Inc. Implantable medical device having optical fiber for sensing electrical activity
US20080221479A1 (en) * 2007-03-07 2008-09-11 Ritchie Paul G Integrated Imaging and Biopsy System with Integrated Utilities
US20080234567A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation Apparatus and method for providing a noninvasive diagnosis of internal bleeding
WO2008116010A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome exemplary laser speckle imaging procedure
JP2008229024A (ja) * 2007-03-20 2008-10-02 Olympus Corp 蛍光観察装置
WO2008118781A2 (en) * 2007-03-23 2008-10-02 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
US10534129B2 (en) * 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
WO2008131082A1 (en) 2007-04-17 2008-10-30 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy techniques
US8115919B2 (en) * 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
US9226731B2 (en) * 2007-05-21 2016-01-05 The Board Of Regents Of The University Of Texas System Optically guided needle biopsy system using multi-modal spectroscopy in combination with a transrectal ultrasound probe
US8591521B2 (en) 2007-06-08 2013-11-26 United States Endoscopy Group, Inc. Retrieval device
US20090003666A1 (en) * 2007-06-27 2009-01-01 Wu Dee H System and methods for image analysis and treatment
WO2009018456A2 (en) * 2007-07-31 2009-02-05 The General Hospital Corporation Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging
EP2191254B1 (de) * 2007-08-31 2017-07-19 The General Hospital Corporation System und verfahren für selbstinterferenz-fluoreszenzmikroskopie und damit assoziiertes rechnerzugriffsmedium
EP2188587A4 (de) * 2007-09-13 2017-01-18 Duke University Vorrichtungen, systeme und verfahren zur interferometrie mit niedriger kohärenz (lci)
EP2197546A1 (de) * 2007-09-14 2010-06-23 Light Sciences Oncology, Inc. Systeme, vorrichtungen und verfahren für die photoaktiv gestützte resektion
US20090073439A1 (en) * 2007-09-15 2009-03-19 The General Hospital Corporation Apparatus, computer-accessible medium and method for measuring chemical and/or molecular compositions of coronary atherosclerotic plaques in anatomical structures
US9220398B2 (en) 2007-10-11 2015-12-29 Intuitive Surgical Operations, Inc. System for managing Bowden cables in articulating instruments
US20090131801A1 (en) * 2007-10-12 2009-05-21 The General Hospital Corporation Systems and processes for optical imaging of luminal anatomic structures
US7933021B2 (en) * 2007-10-30 2011-04-26 The General Hospital Corporation System and method for cladding mode detection
WO2009061832A1 (en) 2007-11-05 2009-05-14 Kci Licensing Inc. Identification of tissue for debridement
US20100268025A1 (en) * 2007-11-09 2010-10-21 Amir Belson Apparatus and methods for capsule endoscopy of the esophagus
US20090124927A1 (en) * 2007-11-13 2009-05-14 Chest Innovations, Inc. Endoscopic system for lung biopsy and biopsy method of insufflating gas to collapse a lung
US7940047B2 (en) 2007-11-23 2011-05-10 Sentinelle Medical, Inc. Microcontroller system for identifying RF coils in the bore of a magnetic resonance imaging system
AU2009204187B2 (en) * 2008-01-08 2015-02-05 Oncoscope, Inc. Systems and methods for tissue examination, diagnostic, treatment, and/or monitoring
US20090225324A1 (en) * 2008-01-17 2009-09-10 The General Hospital Corporation Apparatus for providing endoscopic high-speed optical coherence tomography
US8983580B2 (en) * 2008-01-18 2015-03-17 The Board Of Trustees Of The University Of Illinois Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors
US8115934B2 (en) * 2008-01-18 2012-02-14 The Board Of Trustees Of The University Of Illinois Device and method for imaging the ear using optical coherence tomography
US9332942B2 (en) * 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
EP2249690B1 (de) 2008-02-06 2021-09-29 Intuitive Surgical Operations, Inc. Segmentiertes instrument mit bremsmöglichkeit
US8182418B2 (en) * 2008-02-25 2012-05-22 Intuitive Surgical Operations, Inc. Systems and methods for articulating an elongate body
JP5607610B2 (ja) 2008-05-07 2014-10-15 ザ ジェネラル ホスピタル コーポレイション 構造の特徴を決定する装置、装置の作動方法およびコンピュータアクセス可能な媒体
US8239139B2 (en) * 2008-06-05 2012-08-07 The Regents Of The University Of Michigan Multimodal spectroscopic systems and methods for classifying biological tissue
US8234078B2 (en) * 2008-06-05 2012-07-31 The Regents Of The University Of Michigan Multimodal spectroscopic systems and methods for classifying biological tissue
US8694266B2 (en) 2008-06-05 2014-04-08 The Regents Of The University Of Michigan Multimodal spectroscopic systems and methods for classifying biological tissue
EP2288948A4 (de) * 2008-06-20 2011-12-28 Gen Hospital Corp Anordnung aus kondensierten glasfaserkopplern und verfahren zu ihrer verwendung
US9254089B2 (en) 2008-07-14 2016-02-09 The General Hospital Corporation Apparatus and methods for facilitating at least partial overlap of dispersed ration on at least one sample
US8416405B2 (en) * 2008-08-08 2013-04-09 Chemimage Corporation Raman chemical imaging of implantable drug delivery devices
US20100081915A1 (en) * 2008-09-29 2010-04-01 Searete Llc, Alimited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081916A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware. Histological facilitation systems and methods
US20100081928A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological Facilitation systems and methods
US20100081927A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081926A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081924A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US20110190662A1 (en) * 2008-10-01 2011-08-04 Beacon Endoscopic Corporation Rapid exchange fna biopsy device with diagnostic and therapeutic capabilities
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US8968210B2 (en) * 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US7862219B2 (en) * 2008-10-22 2011-01-04 Advanced Photodynamic Technologies, Inc. Optical fiber light diffusing device
US8937724B2 (en) 2008-12-10 2015-01-20 The General Hospital Corporation Systems and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
WO2010090837A2 (en) 2009-01-20 2010-08-12 The General Hospital Corporation Endoscopic biopsy apparatus, system and method
EP2382456A4 (de) * 2009-01-26 2012-07-25 Gen Hospital Corp System, verfahren und computermedium für mikroskopie mit weitem feld und sehr hoher auflösung
CA2749670A1 (en) 2009-02-04 2010-08-12 The General Hospital Corporation Apparatus and method for utilization of a high-speed optical wavelength tuning source
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
EP2445413B1 (de) * 2009-06-23 2020-02-12 Invivo Corporation Verstellbarer winkelführungshalter für einen biopsieführungsstecker
US8516691B2 (en) * 2009-06-24 2013-08-27 Given Imaging Ltd. Method of assembly of an in vivo imaging device with a flexible circuit board
BR112012001042A2 (pt) 2009-07-14 2016-11-22 Gen Hospital Corp equipamento e método de medição do fluxo de fluído dentro de estrutura anatômica.
FR2948007B1 (fr) * 2009-07-20 2012-06-08 Chab Lama Al Sonde a aiguille fibree tranchante pour le diagnostic optique en profondeur de tumeurs.
US20110137178A1 (en) * 2009-10-06 2011-06-09 The General Hospital Corporation Devices and methods for imaging particular cells including eosinophils
US20110224541A1 (en) * 2009-12-08 2011-09-15 The General Hospital Corporation Methods and arrangements for analysis, diagnosis, and treatment monitoring of vocal folds by optical coherence tomography
TWI511702B (zh) * 2009-12-11 2015-12-11 Univ Ishou Methods for the measurement of endothelial cell dilatation
US9823127B2 (en) 2010-01-22 2017-11-21 Duke University Systems and methods for deep spectroscopic imaging of biological samples with use of an interferometer and spectrometer
CA2787696A1 (en) 2010-01-22 2011-07-28 Adam Wax Multiple window processing schemes for spectroscopic optical coherence tomography (oct) and fourier domain low coherence interferometry
US20110201965A1 (en) * 2010-02-18 2011-08-18 John Anthony Hibner MRI Compatible Biopsy Device
HUE051135T2 (hu) 2010-03-05 2021-03-01 Massachusetts Gen Hospital Rendszerek mikroszkópikus képek elõállítására legalább egy anatómiai szerkezetrõl adott felbontással
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
US8666673B2 (en) 2010-05-14 2014-03-04 Biomerieux, Inc Identification and/or characterization of a microbial agent using taxonomic hierarchical classification
WO2011149972A2 (en) 2010-05-25 2011-12-01 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
JP5778762B2 (ja) 2010-05-25 2015-09-16 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィー画像のスペクトル解析のための装置及び方法
DE102010017117A1 (de) 2010-05-27 2011-12-01 Anne Schardey Chirurgisches Instrument
JP6066901B2 (ja) 2010-06-03 2017-01-25 ザ ジェネラル ホスピタル コーポレイション 1つまたは複数の管腔器官内または管腔器官にある構造を撮像するための装置およびデバイスのための方法
CN102846304A (zh) * 2010-07-15 2013-01-02 广州宝胆医疗器械科技有限公司 诊疗一体化共聚焦阴道镜系统
WO2012056991A1 (ja) 2010-10-26 2012-05-03 コニカミノルタオプト株式会社 プローブ
EP2632324A4 (de) 2010-10-27 2015-04-22 Gen Hospital Corp Vorrichtungen, systeme und verfahren zur blutdruckmessung in mindestens einem gefäss
US9913596B2 (en) 2010-11-25 2018-03-13 Invivo Corporation Systems and methods for MRI guided trans-orifice and transperineal intervention apparatus with adjustable biopsy needle insertion
US8721077B2 (en) 2011-04-29 2014-05-13 The General Hospital Corporation Systems, methods and computer-readable medium for determining depth-resolved physical and/or optical properties of scattering media by analyzing measured data over a range of depths
JP5831543B2 (ja) 2011-05-18 2015-12-09 コニカミノルタ株式会社 プローブ
WO2013013049A1 (en) 2011-07-19 2013-01-24 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
JP5834584B2 (ja) * 2011-07-25 2015-12-24 ソニー株式会社 情報処理装置、情報処理方法、プログラム及び蛍光スペクトルの強度補正方法
WO2013029047A1 (en) 2011-08-25 2013-02-28 The General Hospital Corporation Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
ES2727868T3 (es) 2011-09-22 2019-10-21 Univ George Washington Sistemas para visualizar el tejido ablacionado
JP5926806B2 (ja) 2011-09-22 2016-05-25 ザ・ジョージ・ワシントン・ユニバーシティThe George Washingtonuniversity アブレーションされた組織を視覚化するシステムと方法
US9341783B2 (en) 2011-10-18 2016-05-17 The General Hospital Corporation Apparatus and methods for producing and/or providing recirculating optical delay(s)
EP2833776A4 (de) 2012-03-30 2015-12-09 Gen Hospital Corp Abbildungssystem, verfahren und distaler anschluss zur multidirektionalen sichtfeldendoskopie
US20150038837A1 (en) * 2012-04-05 2015-02-05 Sbi Pharmaceuticals Co., Ltd. Device for determining metastasis of cancer to sentinel lymph node
WO2013177061A1 (en) 2012-05-21 2013-11-28 The Regents Of The University Of Colorado, A Body Corporate Three-dimensional mapping and therapy of prostate cancer
US9814448B2 (en) 2012-05-21 2017-11-14 Precision Biopsy, Inc. Three-dimensional optical imaging and therapy of prostate cancer
WO2013177154A1 (en) 2012-05-21 2013-11-28 The General Hospital Corporation Apparatus, device and method for capsule microscopy
JP6227652B2 (ja) 2012-08-22 2017-11-08 ザ ジェネラル ホスピタル コーポレイション ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体
JPWO2014030344A1 (ja) * 2012-08-23 2016-07-28 Sbiファーマ株式会社 コリメータを備えた光線力学的診断装置
US10322194B2 (en) 2012-08-31 2019-06-18 Sloan-Kettering Institute For Cancer Research Particles, methods and uses thereof
JP6250694B2 (ja) * 2012-11-26 2017-12-20 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 螺旋状生検装置
WO2014085911A1 (en) 2012-12-05 2014-06-12 Tornado Medical Systems, Inc. System and method for wide field oct imaging
US10105456B2 (en) 2012-12-19 2018-10-23 Sloan-Kettering Institute For Cancer Research Multimodal particles, methods and uses thereof
WO2014117130A1 (en) 2013-01-28 2014-07-31 The General Hospital Corporation Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging
WO2014120791A1 (en) 2013-01-29 2014-08-07 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
US11179028B2 (en) 2013-02-01 2021-11-23 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
CA2900686A1 (en) 2013-02-20 2014-08-28 Sloan-Kettering Institute For Cancer Research Wide field raman imaging apparatus and associated methods
US9526579B2 (en) * 2013-03-12 2016-12-27 Boston Scientific Scimed, Inc. Combination diffused and focused fiber optic for diagnosis and treatment of diseased cells
BR112015022944A2 (pt) * 2013-03-15 2017-07-18 Olive Medical Corp calibração com o uso de tampa distal
EP2967491B1 (de) 2013-03-15 2022-05-11 The General Hospital Corporation Ein transösophageales endoskopisches system zur bestimmung einer gemischten venösen sauerstoffsättigung einer lungenarterie
ES2961685T3 (es) 2013-03-15 2024-03-13 Hologic Inc Sistema y método de revisión y análisis de muestras citológicas
JP5988907B2 (ja) * 2013-03-27 2016-09-07 オリンパス株式会社 内視鏡システム
WO2014157793A1 (ko) 2013-03-29 2014-10-02 주식회사 레이언스 맘모그래피 장치 및 그의 위치 정렬 제어 방법
EP2997354A4 (de) 2013-05-13 2017-01-18 The General Hospital Corporation Erkennung einer selbstinterferierenden fluoreszenzphase und amplitude
US10531862B2 (en) 2013-06-26 2020-01-14 General Electric Company System and method for attaching a biopsy collecting device to a spectroscopy system
US9913628B2 (en) 2013-06-26 2018-03-13 General Electric Company System and method for attaching a biopsy collecting device to a spectroscopy system
EP4349242A2 (de) 2013-07-19 2024-04-10 The General Hospital Corporation Bildgebungsvorrichtung und verfahren mit multidirektionaler sichtfeldendoskopie
WO2015010133A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
US9668652B2 (en) 2013-07-26 2017-06-06 The General Hospital Corporation System, apparatus and method for utilizing optical dispersion for fourier-domain optical coherence tomography
US9572591B2 (en) 2013-09-03 2017-02-21 United States Endoscopy Group, Inc. Endoscopic snare device
US9872700B2 (en) 2013-09-03 2018-01-23 United States Endoscopy Group, Inc. Endoscopic snare device
JP6737705B2 (ja) 2013-11-14 2020-08-12 ザ・ジョージ・ワシントン・ユニバーシティThe George Washingtonuniversity 損傷部位の深さを決定するシステムの動作方法及び心臓組織の画像を生成するシステム
US20150141847A1 (en) 2013-11-20 2015-05-21 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
WO2015116986A2 (en) 2014-01-31 2015-08-06 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
US10912947B2 (en) 2014-03-04 2021-02-09 Memorial Sloan Kettering Cancer Center Systems and methods for treatment of disease via application of mechanical force by controlled rotation of nanoparticles inside cells
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
CN104000530B (zh) * 2014-06-06 2016-08-24 慈溪市桥头京姬电子元件厂 一种临时洗手装置
US10912462B2 (en) 2014-07-25 2021-02-09 The General Hospital Corporation Apparatus, devices and methods for in vivo imaging and diagnosis
JP2017523181A (ja) 2014-07-28 2017-08-17 メモリアル スローン−ケタリング キャンサー センター 医療用同位体のためのユニバーサル結合剤としての金属(メタロイド)カルコゲンナノ粒子
EP3215002B1 (de) 2014-11-03 2024-03-20 The George Washington University Systeme zur läsionsbeurteilung
CN107427213B (zh) 2014-11-03 2021-04-16 460医学股份有限公司 用于接触质量的评估的系统和方法
WO2016149701A1 (en) 2015-03-19 2016-09-22 The Regents Of The University Of Michigan System for analyzing tissue
EP3317035A1 (de) 2015-07-01 2018-05-09 Memorial Sloan Kettering Cancer Center Anisotrope partikel, verfahren und verwendungen dafür
WO2017007870A1 (en) * 2015-07-07 2017-01-12 Precision Biopsy, Inc. Motorized optical imaging of prostate cancer
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
US10537225B2 (en) * 2016-11-28 2020-01-21 Olympus Corporation Marking method and resecting method
CN110402385A (zh) * 2016-12-15 2019-11-01 美国杰莫洛吉克尔研究所有限公司 用于筛选宝石的装置和方法
EP3565490B1 (de) 2017-01-09 2023-11-01 United States Endoscopy Group, Inc. Endoskopische schlingenvorrichtung
US10806334B2 (en) * 2017-02-28 2020-10-20 Verily Life Sciences Llc System and method for multiclass classification of images using a programmable light source
US11071458B2 (en) * 2017-06-30 2021-07-27 Agency For Science, Technology And Research SERS-active opto-fluidic photonic crystal fiber probe as biopsy needle and optofluidic sensor
US11234600B2 (en) * 2017-07-13 2022-02-01 The Board Of Regents For Oklahoma State University System and method for tissue visualization
WO2019014767A1 (en) 2017-07-18 2019-01-24 Perimeter Medical Imaging, Inc. SAMPLE CONTAINER FOR STABILIZING AND ALIGNING EXCISED ORGANIC TISSUE SAMPLES FOR EX VIVO ANALYSIS
EP3540494B1 (de) 2018-03-16 2022-11-23 Leica Instruments (Singapore) Pte. Ltd. Chirurgisches mikroskop und mikroskopisches verfahren mit erweiterter realität
US20210386278A1 (en) * 2018-11-05 2021-12-16 Mediators Inc. Endoscope fluorescence inspection device
EP3852603A4 (de) 2018-11-05 2022-06-22 Medivators Inc. Endoskopreinigungs- und -inspektionssystem und -verfahren
WO2020112500A1 (en) * 2018-11-30 2020-06-04 Verily Life Sciences Llc Endoscopic systems including a multimode optical fiber and a machine learning classifier for interrogating a portion of a body
EP3730042A1 (de) * 2019-02-07 2020-10-28 Canon U.S.A., Inc. Vorrichtung, verfahren und systeme zur verminderung von thermischem rauschen und umgebungslichtrauschen in der fluoreszenzbildgebung
GB2601789A (en) * 2020-12-10 2022-06-15 Creo Medical Ltd Raman spectroscopy probe, Raman spectroscopy apparatus including the Raman spectroscopy probe and elongate assembly
DE102021204906A1 (de) 2021-05-14 2022-11-17 Richard Wolf Gmbh Biopsiesystem
US20220378295A1 (en) * 2021-05-21 2022-12-01 Dermasensor, Inc. Dynamic Calibration of Light Intensity in a System For Non-invasive Detection of Skin Cancer Using Elastic Scattering Spectroscopy

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5933388B2 (ja) 1976-03-19 1984-08-15 高美 上原 単独操作可能な生検用フアイバ−スコ−プ
US4479499A (en) 1982-01-29 1984-10-30 Alfano Robert R Method and apparatus for detecting the presence of caries in teeth using visible light
WO1983003189A1 (en) 1982-03-16 1983-09-29 Laserscope Inc Surgical device for internal operations
JPS5940830A (ja) 1982-08-31 1984-03-06 浜松ホトニクス株式会社 レ−ザ光パルスを用いた癌の診断装置
US5139025A (en) 1983-10-14 1992-08-18 Somanetics Corporation Method and apparatus for in vivo optical spectroscopic examination
JPS60209146A (ja) * 1984-03-31 1985-10-21 Olympus Optical Co Ltd 螢光スペクトル分析装置
US4651201A (en) * 1984-06-01 1987-03-17 Arnold Schoolman Stereoscopic endoscope arrangement
US4718417A (en) 1985-03-22 1988-01-12 Massachusetts Institute Of Technology Visible fluorescence spectral diagnostic for laser angiosurgery
US5199431A (en) 1985-03-22 1993-04-06 Massachusetts Institute Of Technology Optical needle for spectroscopic diagnosis
US5106387A (en) 1985-03-22 1992-04-21 Massachusetts Institute Of Technology Method for spectroscopic diagnosis of tissue
US5104392A (en) 1985-03-22 1992-04-14 Massachusetts Institute Of Technology Laser spectro-optic imaging for diagnosis and treatment of diseased tissue
US5318024A (en) 1985-03-22 1994-06-07 Massachusetts Institute Of Technology Laser endoscope for spectroscopic imaging
US5125404A (en) 1985-03-22 1992-06-30 Massachusetts Institute Of Technology Apparatus and method for obtaining spectrally resolved spatial images of tissue
CN85100424B (zh) 1985-04-01 1986-10-29 上海医疗器械研究所 恶性肿瘤固有荧光诊断仪
AT387860B (de) 1985-09-16 1989-03-28 Optical Sensing Technology Verfahren und vorrichtung zur tumordiagnose mittels sera
US5042494A (en) 1985-11-13 1991-08-27 Alfano Robert R Method and apparatus for detecting cancerous tissue using luminescence excitation spectra
US4895156A (en) 1986-07-02 1990-01-23 Schulze John E Sensor system using fluorometric decay measurements
US4981138A (en) 1988-06-30 1991-01-01 Yale University Endoscopic fiberoptic fluorescence spectrometer
US5122974A (en) 1989-02-06 1992-06-16 Nim, Inc. Phase modulated spectrophotometry
US5402778A (en) 1993-01-19 1995-04-04 Nim Incorporated Spectrophotometric examination of tissue of small dimension
US4972331A (en) 1989-02-06 1990-11-20 Nim, Inc. Phase modulated spectrophotometry
US5596987A (en) 1988-11-02 1997-01-28 Noninvasive Technology, Inc. Optical coupler for in vivo examination of biological tissue
US5187672A (en) 1989-02-06 1993-02-16 Nim Incorporated Phase modulation spectroscopic system
ATE133545T1 (de) 1988-12-21 1996-02-15 Massachusetts Inst Technology Verfahren für laserinduzierte fluoreszenz von gewebe
US5555885A (en) 1988-12-21 1996-09-17 Non-Invasive Technology, Inc. Examination of breast tissue using time-resolved spectroscopy
US5553614A (en) 1988-12-21 1996-09-10 Non-Invasive Technology, Inc. Examination of biological tissue using frequency domain spectroscopy
US5386827A (en) 1993-03-30 1995-02-07 Nim Incorporated Quantitative and qualitative in vivo tissue examination using time resolved spectroscopy
US5353799A (en) 1991-01-22 1994-10-11 Non Invasive Technology, Inc. Examination of subjects using photon migration with high directionality techniques
SE8900612D0 (sv) 1989-02-22 1989-02-22 Jonas Johansson Vaevnadskarakterisering utnyttjande ett blodfritt fluorescenskriterium
US5421337A (en) 1989-04-14 1995-06-06 Massachusetts Institute Of Technology Spectral diagnosis of diseased tissue
US5201318A (en) 1989-04-24 1993-04-13 Rava Richard P Contour mapping of spectral diagnostics
US5369496A (en) 1989-11-13 1994-11-29 Research Foundation Of City College Of New York Noninvasive method and apparatus for characterizing biological materials
JP2852774B2 (ja) 1989-11-22 1999-02-03 株式会社エス・エル・ティ・ジャパン 生体組織の診断装置およびこの診断装置を備えた治療装置
US5131398A (en) 1990-01-22 1992-07-21 Mediscience Technology Corp. Method and apparatus for distinguishing cancerous tissue from benign tumor tissue, benign tissue or normal tissue using native fluorescence
US5431645A (en) * 1990-05-10 1995-07-11 Symbiosis Corporation Remotely activated endoscopic tools such as endoscopic biopsy forceps
US5062428A (en) 1990-06-04 1991-11-05 Nim Incorporated Method and device for in vivo diagnosis detecting IR emission by body organ
WO1992007245A1 (en) 1990-10-10 1992-04-30 The University Of Maryland Method and apparatus for performing phase fluorescence lifetime measurements in flow cytometry
EP0568596A1 (de) 1991-01-24 1993-11-10 The University Of Maryland Verfahren und gerät zur mehrdimensionalen abbildung mit verwendung der phasenfluoreszenzlebzeit
US5168162A (en) 1991-02-04 1992-12-01 Cornell Research Foundation, Inc. Method of detecting the presence of anomalies in exfoliated cells using infrared spectroscopy
US5261410A (en) 1991-02-07 1993-11-16 Alfano Robert R Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy
US5303026A (en) 1991-02-26 1994-04-12 The Regents Of The University Of California Los Alamos National Laboratory Apparatus and method for spectroscopic analysis of scattering media
US5318023A (en) 1991-04-03 1994-06-07 Cedars-Sinai Medical Center Apparatus and method of use for a photosensitizer enhanced fluorescence based biopsy needle
US5293872A (en) * 1991-04-03 1994-03-15 Alfano Robert R Method for distinguishing between calcified atherosclerotic tissue and fibrous atherosclerotic tissue or normal cardiovascular tissue using Raman spectroscopy
US5377676A (en) 1991-04-03 1995-01-03 Cedars-Sinai Medical Center Method for determining the biodistribution of substances using fluorescence spectroscopy
US5321501A (en) 1991-04-29 1994-06-14 Massachusetts Institute Of Technology Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample
US6134003A (en) * 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US5465147A (en) 1991-04-29 1995-11-07 Massachusetts Institute Of Technology Method and apparatus for acquiring images using a ccd detector array and no transverse scanner
US5196709A (en) 1991-05-03 1993-03-23 University Of Maryland Systems Fluorometry method and apparatus using a semiconductor laser diode as a light source
CA2042075C (en) 1991-05-08 2001-01-23 Branko Palcic Endoscopic imaging system
US5203328A (en) 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5348018A (en) 1991-11-25 1994-09-20 Alfano Robert R Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy
US5467767A (en) 1991-11-25 1995-11-21 Alfano; Robert R. Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy
US5635402A (en) 1992-03-05 1997-06-03 Alfano; Robert R. Technique for determining whether a cell is malignant as opposed to non-malignant using extrinsic fluorescence spectroscopy
US5383467A (en) 1992-11-18 1995-01-24 Spectrascience, Inc. Guidewire catheter and apparatus for diagnostic imaging
ES2102187T3 (es) 1992-11-18 1997-07-16 Spectrascience Inc Aparato para diagnostico por formacion de imagenes.
US5350375A (en) 1993-03-15 1994-09-27 Yale University Methods for laser induced fluorescence intensity feedback control during laser angioplasty
US5413108A (en) 1993-04-21 1995-05-09 The Research Foundation Of City College Of New York Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor
US5349964A (en) 1993-05-05 1994-09-27 Intelliwire, Inc. Device having an electrically actuatable section with a portion having a current shunt and method
US5421339A (en) 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence
US5673701A (en) 1994-10-07 1997-10-07 Non Invasive Technology, Inc. Optical techniques for examination of biological tissue
US5474910A (en) 1993-10-15 1995-12-12 Alfano; Robert R. Method and device for detecting biological molecules and/or microorganisms within a desired area or space
US5408966A (en) 1993-12-23 1995-04-25 Ford Motor Company System and method for synchronously activating cylinders within a variable displacement engine
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5650135A (en) 1994-07-01 1997-07-22 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US5599717A (en) 1994-09-02 1997-02-04 Martin Marietta Energy Systems, Inc. Advanced synchronous luminescence system
US5579773A (en) 1994-09-30 1996-12-03 Martin Marietta Energy Systems, Inc. Laser-induced differential normalized fluorescence method for cancer diagnosis
JPH08224240A (ja) * 1995-02-22 1996-09-03 Olympus Optical Co Ltd 蛍光診断装置
US5612540A (en) 1995-03-31 1997-03-18 Board Of Regents, The University Of Texas Systems Optical method for the detection of cervical neoplasias using fluorescence spectroscopy
DE19533856A1 (de) * 1995-09-13 1997-03-20 Balazs Mattias Medizinisches Instrument
IT1277690B1 (it) * 1995-12-22 1997-11-11 Bieffe Medital Spa Sistema di sostegno ed attuazione a vertebre in particolare per strumenti chirurgici e diagnostici
US5647368A (en) 1996-02-28 1997-07-15 Xillix Technologies Corp. Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract
US5762613A (en) 1996-05-07 1998-06-09 Spectrascience, Inc. Optical biopsy forceps
US5843000A (en) * 1996-05-07 1998-12-01 The General Hospital Corporation Optical biopsy forceps and method of diagnosing tissue

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JP2010088929A (ja) 2010-04-22
EP1065970B1 (de) 2008-10-29
JP2002505900A (ja) 2002-02-26
US6174291B1 (en) 2001-01-16
CA2322768C (en) 2008-08-05
CA2322768A1 (en) 1999-09-16
EP2018824B1 (de) 2010-07-21
WO1999045838A1 (en) 1999-09-16
JP4477230B2 (ja) 2010-06-09
EP1065970A1 (de) 2001-01-10
ATE474498T1 (de) 2010-08-15
EP2018824A1 (de) 2009-01-28
ATE412363T1 (de) 2008-11-15
DE69939818D1 (de) 2008-12-11

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