DE69942459D1 - Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung - Google Patents

Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung

Info

Publication number
DE69942459D1
DE69942459D1 DE69942459T DE69942459T DE69942459D1 DE 69942459 D1 DE69942459 D1 DE 69942459D1 DE 69942459 T DE69942459 T DE 69942459T DE 69942459 T DE69942459 T DE 69942459T DE 69942459 D1 DE69942459 D1 DE 69942459D1
Authority
DE
Germany
Prior art keywords
nucleic acid
acid molecules
tif
copying
isolated nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942459T
Other languages
English (en)
Inventor
Laure Dumoutier
Jamila Louhed
Jean-Christophe Renauld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Priority claimed from PCT/US1999/024424 external-priority patent/WO2000024758A1/en
Application granted granted Critical
Publication of DE69942459D1 publication Critical patent/DE69942459D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
DE69942459T 1998-10-26 1999-10-18 Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung Expired - Lifetime DE69942459D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/178,973 US6274710B1 (en) 1998-10-26 1998-10-26 Antibodies which specifically bind T Cell inducible factors (TIFs)
US09/354,243 US6359117B1 (en) 1998-10-26 1999-07-16 Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses therefor
PCT/US1999/024424 WO2000024758A1 (en) 1998-10-26 1999-10-18 ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF

Publications (1)

Publication Number Publication Date
DE69942459D1 true DE69942459D1 (de) 2010-07-15

Family

ID=22654680

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69942459T Expired - Lifetime DE69942459D1 (de) 1998-10-26 1999-10-18 Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung

Country Status (5)

Country Link
US (3) US6274710B1 (de)
CN (1) CN1789411A (de)
AT (1) ATE469911T1 (de)
DE (1) DE69942459D1 (de)
ES (1) ES2346831T3 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
US6551799B2 (en) * 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US6274710B1 (en) * 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
US7081528B2 (en) * 1998-10-26 2006-07-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding T cell derived inducible factors
US7307161B1 (en) * 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
WO2000065027A2 (en) * 1999-04-28 2000-11-02 Genetics Institute, Inc. Human gil-19/ae289 proteins and polynucleotides encoding same
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
WO2001040467A1 (en) * 1999-12-03 2001-06-07 Zymogenetics, Inc. Human cytokine receptor
US7226591B2 (en) * 2000-05-22 2007-06-05 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20030170823A1 (en) * 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
US20030012788A1 (en) * 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22
DE60123998T2 (de) * 2000-08-08 2007-09-06 Zymogenetics, Inc., Seattle Lösliche zcyctor 11 cytokinrezeptoren
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
AU2002252460A1 (en) * 2001-03-27 2002-10-08 Zymogenetics, Inc. Human cytokine receptor
IL164181A0 (en) 2002-03-22 2005-12-18 Zymogenetics Inc Anti-il-tif antibodies and methods of using in inflammation
DE602004028347D1 (de) * 2003-03-24 2010-09-09 Zymogenetics Inc Anti-il-22ra antikörper und bindungspartner und verwendungsmethoden bei entzündung
EP1812476B1 (de) * 2004-10-22 2010-07-21 ZymoGenetics, Inc. Anti-il-22ra-antikörper und bindungspartner und verfahren zur anwendung bei entzündungen
CN100515491C (zh) * 2005-01-04 2009-07-22 健能隆医药技术（上海）有限公司 白介素-22的医药用途
EP1856156A2 (de) * 2005-02-08 2007-11-21 ZymoGenetics, Inc. Anti-il-20-, anti-il-22- und anti-il-22ra-antikörper und bindungspartner sowie verwendungsverfahren bei entzündungen
US7737259B2 (en) * 2005-12-02 2010-06-15 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术（上海）有限公司 白介素-22在治疗脂肪肝中的应用
CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 白介素-22在治疗病毒性肝炎中的应用
JP5947891B2 (ja) 2011-07-25 2016-07-06 ジェネロン（シャンハイ）コーポレイション リミテッドＧｅｎｅｒｏｎ （Ｓｈａｎｇｈａｉ） Ｃｏｒｐｏｒａｔｉｏｎ Ｌｔｄ． 神経変性疾患を治療する医薬品の製造におけるｇ−ｃｓｆ二量体の応用
CN103182072B (zh) 2011-12-27 2017-05-03 健能隆医药技术（上海）有限公司 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途
WO2014053481A1 (en) 2012-10-03 2014-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
ES2739129T5 (es) 2013-11-07 2024-04-02 Memorial Sloan Kettering Cancer Center IL-22 para uso en el tratamiento de la enfermedad gastrointestinal del injerto contra el huesped
CN104623639A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 白介素22二聚体在制备治疗胰腺炎药物中的应用
EP3167892A1 (de) 2015-11-10 2017-05-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren und pharmazeutische zusammensetzungen zur vorbeugung oder behandlung von entzündlichen darmerkrankungen
ES2930351T3 (es) 2016-04-15 2022-12-09 Evive Biotechnology Shanghai Ltd Un dímero de IL-22 para su uso en el tratamiento de enterocolitis necrosante
SG11202012014UA (en) 2018-06-05 2021-01-28 Bioatla Inc Anti-il-22 antibodies, antibody fragments, their immunoconjugates and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1082433A4 (de) 1998-05-29 2003-01-02 Human Genome Sciences Inc Interleukine 21 und 22
US6274710B1 (en) 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
US7081528B2 (en) * 1998-10-26 2006-07-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding T cell derived inducible factors
CA2347066C (en) 1998-10-26 2011-05-03 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode t cell inducible factors (tifs), the proteins encoded, and uses thereof
WO2000065027A2 (en) * 1999-04-28 2000-11-02 Genetics Institute, Inc. Human gil-19/ae289 proteins and polynucleotides encoding same
US6939545B2 (en) 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US7307161B1 (en) * 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
AU5047600A (en) 1999-05-27 2000-12-18 Schering Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
US20030012788A1 (en) 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22

Also Published As

Publication number Publication date
ATE469911T1 (de) 2010-06-15
US7972833B2 (en) 2011-07-05
ES2346831T3 (es) 2010-10-20
US6359117B1 (en) 2002-03-19
US6274710B1 (en) 2001-08-14
CN1789411A (zh) 2006-06-21
US20080213881A1 (en) 2008-09-04

Similar Documents

Publication Publication Date Title
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
DK1458760T3 (da) Indfangede bindingsproteiner som biosensorer
DE60144145D1 (de) Subtilisin-variante
BRPI0412845A (pt) herpes-vìrus, uso de um vìrus, composição farmacêutica, e, método de tratamento de um tumor em um indivìduo em necessidade do mesmo
ATE227739T1 (de) Hybridprotein zur hemmung der mastzelldegranulation und dessen verwendung
EA200401591A1 (ru) Керамические аноды и способ их изготовления
BR9814404A (pt) " clonagem de expressão em fungos filamentosos "
NO20043259L (no) Bindingsproteiner som biosensorer
BR0207775A (pt) Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização
DK1131444T3 (da) Polypeptider med lysophospholipase aktivitet og nucleinsyre som koder for disse
BR0314814A (pt) Variantes otimizadas de fc e métodos para sua geração
MXPA02012743A (es) Moleculas tipo il-17 y usos de las mismas.
WO2004063362A3 (en) Cell cycle progression proteins
DK1005540T3 (da) IKK-beta-proteiner, nukleinsyrer og fremgangsmåder
ATE384119T1 (de) Isoprenoidproduktion
DK1290444T3 (da) Toxicitetstypisering under anvendelse af lever-stamceller
CY1109207T1 (el) Διαδικασια εχινοκανδινης
DE69942861D1 (de) Ldcam genannte moleküle
WO2002010393A3 (en) Isolated nucleic acid molecules which encode t cell inducible factors, or interleukin-21, the proteins encoded, and uses thereof
DE60138715D1 (de) Tnf-rezeptor-ähnliche moleküle und deren anwendungen
DK1117798T3 (da) Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider
SE9801455D0 (sv) New receptor
DK1082423T3 (da) Cyclin E2-gener og -proteiner
DE60139544D1 (de) Veränderte, fluoreszierende proteine
DK1465927T3 (da) BAG3-antistoffer til anvendelse til forskning, diagnostik og behandling af sygdomme, der omfatter celledød