DE69942459D1 - Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung - Google Patents
Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendungInfo
- Publication number
- DE69942459D1 DE69942459D1 DE69942459T DE69942459T DE69942459D1 DE 69942459 D1 DE69942459 D1 DE 69942459D1 DE 69942459 T DE69942459 T DE 69942459T DE 69942459 T DE69942459 T DE 69942459T DE 69942459 D1 DE69942459 D1 DE 69942459D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- acid molecules
- tif
- copying
- isolated nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/178,973 US6274710B1 (en) | 1998-10-26 | 1998-10-26 | Antibodies which specifically bind T Cell inducible factors (TIFs) |
US09/354,243 US6359117B1 (en) | 1998-10-26 | 1999-07-16 | Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses therefor |
PCT/US1999/024424 WO2000024758A1 (en) | 1998-10-26 | 1999-10-18 | ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69942459D1 true DE69942459D1 (de) | 2010-07-15 |
Family
ID=22654680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942459T Expired - Lifetime DE69942459D1 (de) | 1998-10-26 | 1999-10-18 | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung |
Country Status (5)
Country | Link |
---|---|
US (3) | US6274710B1 (de) |
CN (1) | CN1789411A (de) |
AT (1) | ATE469911T1 (de) |
DE (1) | DE69942459D1 (de) |
ES (1) | ES2346831T3 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965704A (en) * | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
US6551799B2 (en) * | 1999-12-07 | 2003-04-22 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
US6274710B1 (en) * | 1998-10-26 | 2001-08-14 | Ludwig Institute For Cancer Research | Antibodies which specifically bind T Cell inducible factors (TIFs) |
US7081528B2 (en) * | 1998-10-26 | 2006-07-25 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules encoding T cell derived inducible factors |
US7307161B1 (en) * | 1999-04-28 | 2007-12-11 | Genetics Institute, Llc | Human Gil-19/AE289 polynucleotides |
US6939545B2 (en) | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
JP4828703B2 (ja) * | 1999-04-28 | 2011-11-30 | ジェネティックス インスティテュート エルエルシー | ヒトgil−19/ae289タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
ATE458814T1 (de) * | 1999-12-03 | 2010-03-15 | Zymogenetics Inc | Menschliches zytokinrezeptor |
US7226591B2 (en) * | 2000-05-22 | 2007-06-05 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
US20030170823A1 (en) | 1999-12-23 | 2003-09-11 | Presnell Scott R. | Novel cytokine ZCYTO18 |
US20030012788A1 (en) * | 2000-07-27 | 2003-01-16 | Jean-Christophe Renauld | Method for influencing kinase pathways with IL-22 |
EP1337636B1 (de) * | 2000-08-08 | 2006-10-18 | ZymoGenetics, Inc. | Lösliche zcyctor 11 cytokinrezeptoren |
US7638604B2 (en) * | 2001-02-23 | 2009-12-29 | Genetics Institute, Llc | Monoclonal antibodies against interleukin-22 |
JP2005503765A (ja) * | 2001-03-27 | 2005-02-10 | ザイモジェネティクス,インコーポレイティド | ヒトサイトカイン受容体 |
EP1546358A4 (de) * | 2002-03-22 | 2006-06-07 | Zymogenetics Inc | Anti-il-tif-antikörper und verfahren zur verwendung bei entzündung |
EA009124B1 (ru) * | 2003-03-24 | 2007-10-26 | Займоджинетикс, Инк. | Антитела против il-20 и связывающие партнеры, а также способы их применения при воспалении |
CA2584157C (en) | 2004-10-22 | 2014-10-14 | Zymogenetics, Inc. | Anti-il-22ra antibodies and binding partners and methods of using in inflammation |
CN100515491C (zh) * | 2005-01-04 | 2009-07-22 | 健能隆医药技术(上海)有限公司 | 白介素-22的医药用途 |
WO2006086396A2 (en) * | 2005-02-08 | 2006-08-17 | Zymogenetics, Inc. | Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation |
KR101453570B1 (ko) * | 2005-12-02 | 2014-10-22 | 제넨테크, 인크. | Il-22 및 il-22r에 결합하는 항체를 포함하는,사이토카인 신호 전달과 관련된 질환 및 장애 치료용조성물 및 치료 방법 |
TWI417301B (zh) | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-22(il-22)之抗體及其用途 |
TW200744634A (en) | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
CN101361968B (zh) | 2007-08-06 | 2011-08-03 | 健能隆医药技术(上海)有限公司 | 白介素-22在治疗脂肪肝中的应用 |
CN102260343A (zh) | 2010-05-25 | 2011-11-30 | 健能隆医药技术(上海)有限公司 | 重组人g-csf二聚体在治疗神经损伤疾病中的用途 |
CN102380091A (zh) | 2010-08-31 | 2012-03-21 | 健能隆医药技术(上海)有限公司 | 白介素-22在治疗病毒性肝炎中的应用 |
CA2842969C (en) | 2011-07-25 | 2018-03-27 | Generon (Shanghai) Corporation Ltd. | Use of g-csf dimer in preparation of medicament for treatment of neurodegenerative diseases |
CN103182072B (zh) | 2011-12-27 | 2017-05-03 | 健能隆医药技术(上海)有限公司 | 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途 |
JP2015532294A (ja) | 2012-10-03 | 2015-11-09 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | インフルエンザ後の細菌重複感染の予防的処置のための方法および薬学的組成物 |
CN104623639A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | 白介素22二聚体在制备治疗胰腺炎药物中的应用 |
WO2015070077A1 (en) | 2013-11-07 | 2015-05-14 | Memorial Sloan-Kettering Cancer Center | Methods of use for il-22 in the treatment of gastrointestinal graft vs. host disease |
CN104623637A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术(上海)有限公司 | Il-22二聚体在制备静脉注射药物中的应用 |
EP3167892A1 (de) | 2015-11-10 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Verfahren und pharmazeutische zusammensetzungen zur vorbeugung oder behandlung von entzündlichen darmerkrankungen |
EP3442562B1 (de) | 2016-04-15 | 2022-09-21 | Evive Biotechnology (Shanghai) Ltd | Ein il-22-dimer zur verwendung in der behandlung der nekrotisierenden enterokolitis |
MX2020013243A (es) | 2018-06-05 | 2021-05-12 | Bioatla Inc | Anticuerpos anti-il-22, fragmentos de anticuerpo, sus inmunoconjugados y usos de los mismos. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030003545A1 (en) | 1998-05-29 | 2003-01-02 | Reinhard Ebner | Interleukins-21 and 22 |
CA2347066C (en) | 1998-10-26 | 2011-05-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which encode t cell inducible factors (tifs), the proteins encoded, and uses thereof |
US7081528B2 (en) * | 1998-10-26 | 2006-07-25 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules encoding T cell derived inducible factors |
US6274710B1 (en) | 1998-10-26 | 2001-08-14 | Ludwig Institute For Cancer Research | Antibodies which specifically bind T Cell inducible factors (TIFs) |
JP4828703B2 (ja) * | 1999-04-28 | 2011-11-30 | ジェネティックス インスティテュート エルエルシー | ヒトgil−19/ae289タンパク質、及び、同タンパク質をコードするポリヌクレオチド |
US6939545B2 (en) | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
US7307161B1 (en) * | 1999-04-28 | 2007-12-11 | Genetics Institute, Llc | Human Gil-19/AE289 polynucleotides |
WO2000073457A1 (en) | 1999-05-27 | 2000-12-07 | Schering-Corporation | Mammalian interleukin-10 homologs: il-d110 and il-d210 |
US20030012788A1 (en) | 2000-07-27 | 2003-01-16 | Jean-Christophe Renauld | Method for influencing kinase pathways with IL-22 |
-
1998
- 1998-10-26 US US09/178,973 patent/US6274710B1/en not_active Expired - Fee Related
-
1999
- 1999-07-16 US US09/354,243 patent/US6359117B1/en not_active Expired - Fee Related
- 1999-10-18 CN CNA2005101169982A patent/CN1789411A/zh active Pending
- 1999-10-18 ES ES99953231T patent/ES2346831T3/es not_active Expired - Lifetime
- 1999-10-18 AT AT99953231T patent/ATE469911T1/de not_active IP Right Cessation
- 1999-10-18 DE DE69942459T patent/DE69942459D1/de not_active Expired - Lifetime
-
2007
- 2007-09-21 US US11/902,473 patent/US7972833B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20080213881A1 (en) | 2008-09-04 |
US7972833B2 (en) | 2011-07-05 |
US6274710B1 (en) | 2001-08-14 |
US6359117B1 (en) | 2002-03-19 |
ATE469911T1 (de) | 2010-06-15 |
CN1789411A (zh) | 2006-06-21 |
ES2346831T3 (es) | 2010-10-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69942459D1 (de) | Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung | |
DK1458760T3 (da) | Indfangede bindingsproteiner som biosensorer | |
ATE500323T1 (de) | Subtilisin-variante | |
BRPI0412845A (pt) | herpes-vìrus, uso de um vìrus, composição farmacêutica, e, método de tratamento de um tumor em um indivìduo em necessidade do mesmo | |
ATE227739T1 (de) | Hybridprotein zur hemmung der mastzelldegranulation und dessen verwendung | |
EA200401591A1 (ru) | Керамические аноды и способ их изготовления | |
BR9814404A (pt) | " clonagem de expressão em fungos filamentosos " | |
NO20043259L (no) | Bindingsproteiner som biosensorer | |
BR0207775A (pt) | Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização | |
DK1131444T3 (da) | Polypeptider med lysophospholipase aktivitet og nucleinsyre som koder for disse | |
BR0314814A (pt) | Variantes otimizadas de fc e métodos para sua geração | |
MXPA02012743A (es) | Moleculas tipo il-17 y usos de las mismas. | |
BR0215405A (pt) | Composições e processos de uso de collajolie | |
WO2004063362A3 (en) | Cell cycle progression proteins | |
DK1005540T3 (da) | IKK-beta-proteiner, nukleinsyrer og fremgangsmåder | |
ATE384119T1 (de) | Isoprenoidproduktion | |
DK1290444T3 (da) | Toxicitetstypisering under anvendelse af lever-stamceller | |
CY1109207T1 (el) | Διαδικασια εχινοκανδινης | |
DE69942861D1 (de) | Ldcam genannte moleküle | |
WO2002010393A3 (en) | Isolated nucleic acid molecules which encode t cell inducible factors, or interleukin-21, the proteins encoded, and uses thereof | |
DE60138715D1 (de) | Tnf-rezeptor-ähnliche moleküle und deren anwendungen | |
DK1117798T3 (da) | Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider | |
SE9801455D0 (sv) | New receptor | |
DK1082423T3 (da) | Cyclin E2-gener og -proteiner | |
ATE439441T1 (de) | Veränderte, fluoreszierende proteine |