DE69934792D1 - Antikörper gegen dendritische zellen und menschliche dendritische zellpopulationen und deren verwendungen - Google Patents
Antikörper gegen dendritische zellen und menschliche dendritische zellpopulationen und deren verwendungenInfo
- Publication number
- DE69934792D1 DE69934792D1 DE69934792T DE69934792T DE69934792D1 DE 69934792 D1 DE69934792 D1 DE 69934792D1 DE 69934792 T DE69934792 T DE 69934792T DE 69934792 T DE69934792 T DE 69934792T DE 69934792 D1 DE69934792 D1 DE 69934792D1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- cell populations
- human
- dendritic
- dendritic cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000004027 cell Anatomy 0.000 title 1
- 210000004443 dendritic cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/05—Adjuvants
- C12N2501/052—Lipopolysaccharides [LPS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/59—Lectins
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98108534 | 1998-05-11 | ||
PCT/EP1999/003218 WO1999058678A2 (en) | 1998-05-11 | 1999-05-11 | Antibodies to dendritic cells and human dendritic cell populations and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69934792D1 true DE69934792D1 (de) | 2007-02-22 |
Family
ID=8231912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69934792T Expired - Lifetime DE69934792D1 (de) | 1998-05-11 | 1999-05-11 | Antikörper gegen dendritische zellen und menschliche dendritische zellpopulationen und deren verwendungen |
Country Status (8)
Country | Link |
---|---|
US (1) | US20070014798A1 (de) |
EP (1) | EP1078060B1 (de) |
JP (2) | JP2002514420A (de) |
AU (1) | AU4039999A (de) |
CA (1) | CA2328415A1 (de) |
DE (1) | DE69934792D1 (de) |
IL (1) | IL139435A0 (de) |
WO (1) | WO1999058678A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7273753B2 (en) * | 1996-08-02 | 2007-09-25 | Center Of Blood Research | Purification and uses of dendritic cells and monocytes |
US6407218B1 (en) * | 1997-11-10 | 2002-06-18 | Cytimmune Sciences, Inc. | Method and compositions for enhancing immune response and for the production of in vitro mabs |
US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
AU2001261383B2 (en) | 2000-05-08 | 2004-10-21 | Celldex Therapeutics, Inc. | Human monoclonal antibodies to dendritic cells |
ATE552860T1 (de) | 2003-01-31 | 2012-04-15 | Celldex Res Corp | Antikörper-vakzine-konjugate und ihre verwendungen |
US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
EP1694301A4 (de) * | 2003-12-02 | 2009-11-18 | Cytimmune Sciences Inc | Verfahren und zusammensetzungen zur herstellung von monoklonalen antikörpern |
JPWO2008056734A1 (ja) * | 2006-11-08 | 2010-02-25 | 国立大学法人 熊本大学 | ヒト胚性幹細胞からの樹状細胞の製造方法 |
EA201692127A1 (ru) | 2007-11-07 | 2017-08-31 | Селлдекс Терапьютикс Инк. | Антитела, связывающиеся с человеческим dec-205 |
US7960145B2 (en) * | 2007-11-08 | 2011-06-14 | Cytimmune Sciences, Inc. | Compositions and methods for generating antibodies |
DE102010039019B4 (de) | 2010-08-06 | 2014-08-07 | Technische Universität Dresden | Antikörper gegen 6-sulfo LacNAc positive humane dendritische Zellen und deren Verwendung |
EP2768861A1 (de) * | 2011-10-21 | 2014-08-27 | Institut National de la Sante et de la Recherche Medicale (INSERM) | M-dc8+-monozyten-depletionswirkstoff zur vorbeugung oder behandlung eines leidens im zusammenhang mit chronischer überaktivierung des immunsystems |
FR3018819A1 (fr) * | 2014-03-19 | 2015-09-25 | Univ Bourgogne | Traitement de la reponse inflammatoire et dysimmunitaire |
GB201515934D0 (en) * | 2015-09-09 | 2015-10-21 | Rolls Royce Plc | Method of manufacturing a gas turbine engine |
KR101898032B1 (ko) * | 2018-04-20 | 2018-09-12 | (주)해양정보기술 | 지형변화 측량을 통한 측지정보 데이터 수집시스템 |
WO2019244973A1 (ja) * | 2018-06-20 | 2019-12-26 | 中外製薬株式会社 | 標的細胞に対する免疫反応を活性化する方法およびその組成物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3920358A1 (de) * | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
GB9117522D0 (en) * | 1991-08-14 | 1991-10-02 | Medical Res Council | Ligands for dendritic cells, their uses and production |
US5710262A (en) * | 1992-04-17 | 1998-01-20 | Dana-Faber Cancer Institute, Inc. | Nucleic acid encoding HB15 polypeptides |
WO1995012409A1 (en) * | 1993-11-04 | 1995-05-11 | Canterbury Health Limited | Dendritic cell-specific antibodies and methods for their preparation |
US5788963A (en) * | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
DE69731977T2 (de) * | 1996-10-09 | 2005-12-08 | Canterbury Health Ltd. | Spezifische antikörper für dendritische zellen |
-
1999
- 1999-05-11 CA CA002328415A patent/CA2328415A1/en not_active Abandoned
- 1999-05-11 JP JP2000548469A patent/JP2002514420A/ja active Pending
- 1999-05-11 AU AU40399/99A patent/AU4039999A/en not_active Abandoned
- 1999-05-11 DE DE69934792T patent/DE69934792D1/de not_active Expired - Lifetime
- 1999-05-11 WO PCT/EP1999/003218 patent/WO1999058678A2/en active IP Right Grant
- 1999-05-11 EP EP99923574A patent/EP1078060B1/de not_active Expired - Lifetime
- 1999-05-11 IL IL13943599A patent/IL139435A0/xx unknown
-
2006
- 2006-09-22 US US11/524,875 patent/US20070014798A1/en not_active Abandoned
- 2006-10-25 JP JP2006289998A patent/JP2007125012A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO1999058678A9 (en) | 2001-03-22 |
IL139435A0 (en) | 2001-11-25 |
EP1078060A2 (de) | 2001-02-28 |
US20070014798A1 (en) | 2007-01-18 |
WO1999058678A3 (en) | 2000-02-10 |
JP2007125012A (ja) | 2007-05-24 |
CA2328415A1 (en) | 1999-11-18 |
EP1078060B1 (de) | 2007-01-10 |
JP2002514420A (ja) | 2002-05-21 |
AU4039999A (en) | 1999-11-29 |
WO1999058678A2 (en) | 1999-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |