DE69930155D1 - Spray verabreichung von zellen - Google Patents
Spray verabreichung von zellenInfo
- Publication number
- DE69930155D1 DE69930155D1 DE69930155T DE69930155T DE69930155D1 DE 69930155 D1 DE69930155 D1 DE 69930155D1 DE 69930155 T DE69930155 T DE 69930155T DE 69930155 T DE69930155 T DE 69930155T DE 69930155 D1 DE69930155 D1 DE 69930155D1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- fibrin
- target surface
- related protein
- spray administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/225—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0629—Keratinocytes; Whole skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/56—Fibrin; Thrombin
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11061498P | 1998-12-02 | 1998-12-02 | |
US110614P | 1998-12-02 | ||
US15540399P | 1999-09-22 | 1999-09-22 | |
US155403P | 1999-09-22 | ||
PCT/US1999/028524 WO2000032207A1 (en) | 1998-12-02 | 1999-12-02 | Spray delivery of cells |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69930155D1 true DE69930155D1 (de) | 2006-04-27 |
DE69930155T2 DE69930155T2 (de) | 2006-11-23 |
Family
ID=26808226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69930155T Expired - Lifetime DE69930155T2 (de) | 1998-12-02 | 1999-12-02 | Spray verabreichung von zellen |
Country Status (12)
Country | Link |
---|---|
US (1) | US6479052B1 (de) |
EP (1) | EP1143983B1 (de) |
JP (1) | JP2002531176A (de) |
AT (1) | ATE318608T1 (de) |
AU (1) | AU764347B2 (de) |
CA (1) | CA2352810A1 (de) |
DE (1) | DE69930155T2 (de) |
DK (1) | DK1143983T3 (de) |
ES (1) | ES2257877T3 (de) |
NO (1) | NO20012695L (de) |
NZ (1) | NZ528340A (de) |
WO (1) | WO2000032207A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10025609A1 (de) * | 2000-05-24 | 2001-12-13 | Univ Ludwigs Albert | Transfektionssystem |
US7144729B2 (en) * | 2000-09-01 | 2006-12-05 | Dfb Pharmaceuticals, Inc. | Methods and compositions for tissue regeneration |
EP1357922B1 (de) * | 2001-02-07 | 2011-05-25 | McComb Foundation Inc. | Zellsuspensionsherstellungstechnik und verwendung |
AUPR298901A0 (en) | 2001-02-07 | 2001-03-08 | McComb Foundation, Inc., The | Cell suspension preparation technique and device |
DE10116362A1 (de) * | 2001-04-02 | 2002-10-10 | Biotissue Technologies Ag | Zwei-Komponenten Zusammensetzungen zur in situ Herstellung v. Fibroblasten und Keratinozyten umfassenden Zelltransplantaten |
DE10204405A1 (de) * | 2002-02-04 | 2003-08-21 | Surface Care Gmbh | Plasmagel |
US7588564B2 (en) * | 2002-07-03 | 2009-09-15 | Pharmaco Kinesis Corporation | Apparatus for piezoelectric layer-wise pump and valve for use in local administration of biological response modifiers and therapeutic agents |
US7641898B2 (en) * | 2003-03-21 | 2010-01-05 | Materials Evolution And Development Usa, Inc. | Keratinocyte-fibrocyte concomitant grafting for wound healing |
US20040193284A1 (en) * | 2003-03-25 | 2004-09-30 | Taheri Syde A. | Myometrium as a source for cardiomyoplasty |
US7766900B2 (en) | 2005-02-21 | 2010-08-03 | Biomet Manufacturing Corp. | Method and apparatus for application of a fluid |
WO2007019468A2 (en) * | 2005-08-05 | 2007-02-15 | Dixon David M | Apparatus and method to treat a wound area |
DE102007040252A1 (de) | 2006-09-11 | 2008-06-12 | Gerlach, Jörg, Prof. Dr. | Sprühapparat für Zellen und Methode zur Anwendung gesprühter Zellen |
WO2009100219A1 (en) * | 2008-02-05 | 2009-08-13 | University Of Virginia Patent Foundation | Spraying device and related method for cell aggregates and cell aggregate suspension thereof |
US8518272B2 (en) | 2008-04-04 | 2013-08-27 | Biomet Biologics, Llc | Sterile blood separating system |
CN102533652B (zh) * | 2010-12-11 | 2014-01-15 | 清华大学 | 神经移植体的制备方法 |
DE102011100450B8 (de) | 2011-04-27 | 2013-10-17 | Jörg Gerlach | Apparat zum Sprühen von Zellen, Herstellung des Apparates, Methode zum Sprühen mit dem Apparat und eine Zellsuspension gesprüht mit dem Apparat |
KR101335176B1 (ko) * | 2011-12-12 | 2013-11-29 | 테고사이언스 (주) | 상처 치유용 드레싱재제 |
DE102011122227A1 (de) * | 2011-12-23 | 2013-06-27 | Medizinische Hochschule Hannover | Verfahren und Vorrichtung zur Herstellung eines bioartifiziellen Gewebekonstrukts |
US20160008506A1 (en) * | 2013-03-07 | 2016-01-14 | Neostem, Inc. | Stem cell compositions and methods for would healing |
AU2013205148B2 (en) | 2013-03-14 | 2014-10-30 | AVITA Medical Americas, LLC | Systems and methods for tissue processing and preparation of cell suspension therefrom |
EP2969177A1 (de) | 2013-03-15 | 2016-01-20 | Massachusetts Institute of Technology | Abscheidung und abbildung von teilchen auf planaren substraten |
MX342233B (es) * | 2014-02-04 | 2016-08-24 | Alvaro Galue Eduardo | Proceso de obtencion de un compuesto de aspersion celular de fibroblastos y queratinocitos humanos en solucion y su uso como agente regenerativo de lesiones cutáneas. |
AU2017283496B2 (en) | 2016-06-14 | 2020-07-16 | Renovacare Sciences Corp. | Modular device for cell spraying |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE111360T1 (de) * | 1988-05-02 | 1994-09-15 | Project Hear | Chirurgisches klebstoffmaterial. |
FR2639958B1 (fr) * | 1988-12-06 | 1992-08-21 | Lille Transfusion Sanguine | Support biologique pour cultures cellulaires constitue de proteines plasmatiques coagulees par la thrombine, son utilisation pour la culture des keratinocytes, leur recuperation et leur transport a des fins d'utilisation therapeutique |
US5376118A (en) * | 1989-05-10 | 1994-12-27 | United States Surgical Corporation | Support material for cell impregnation |
DE69013764T2 (de) * | 1989-06-03 | 1995-03-30 | Kanegafuchi Chemical Ind | Kontrolle der Zellanordnung. |
FR2663226B1 (fr) * | 1990-06-15 | 1994-11-18 | Fondation Nale Transfusion San | Colle biologique fluide. |
DK83092D0 (da) | 1992-06-24 | 1992-06-24 | Unes As | Fremgangsmaade til udvinding af thrombin |
CN1091315A (zh) * | 1992-10-08 | 1994-08-31 | E·R·斯奎布父子公司 | 血纤维蛋白封闭剂组合物及其使用方法 |
EP0759762A4 (de) * | 1994-05-02 | 1999-09-01 | Squibb & Sons Inc | Rekombinante fibrinketten, fibrin und fibrinhomologe |
US5733545A (en) * | 1995-03-03 | 1998-03-31 | Quantic Biomedical Partners | Platelet glue wound sealant |
WO1997029792A1 (en) * | 1996-02-20 | 1997-08-21 | Cohesion Corporation | Tissue sealant compositions and methods of use thereof |
AU3990197A (en) * | 1996-10-04 | 1998-04-09 | Metropolitan Health Service Board | Method of engraftment of cultured cells |
NZ335751A (en) * | 1996-11-15 | 2001-01-26 | Bristol Myers Squibb Co | Devices and methods for applying a mixture of two or more liquid components to form a biomaterial |
JP3333108B2 (ja) * | 1997-04-08 | 2002-10-07 | 学校法人東海大学 | 上皮性組織移植片およびその製造方法 |
-
1999
- 1999-12-02 DK DK99961914T patent/DK1143983T3/da active
- 1999-12-02 NZ NZ528340A patent/NZ528340A/en unknown
- 1999-12-02 JP JP2000584902A patent/JP2002531176A/ja not_active Withdrawn
- 1999-12-02 AT AT99961914T patent/ATE318608T1/de not_active IP Right Cessation
- 1999-12-02 US US09/453,256 patent/US6479052B1/en not_active Expired - Lifetime
- 1999-12-02 AU AU18402/00A patent/AU764347B2/en not_active Ceased
- 1999-12-02 EP EP99961914A patent/EP1143983B1/de not_active Expired - Lifetime
- 1999-12-02 WO PCT/US1999/028524 patent/WO2000032207A1/en active IP Right Grant
- 1999-12-02 CA CA002352810A patent/CA2352810A1/en not_active Abandoned
- 1999-12-02 ES ES99961914T patent/ES2257877T3/es not_active Expired - Lifetime
- 1999-12-02 DE DE69930155T patent/DE69930155T2/de not_active Expired - Lifetime
-
2001
- 2001-05-31 NO NO20012695A patent/NO20012695L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20012695L (no) | 2001-07-03 |
AU764347B2 (en) | 2003-08-14 |
DK1143983T3 (da) | 2006-04-10 |
EP1143983B1 (de) | 2006-03-01 |
CA2352810A1 (en) | 2000-06-08 |
ES2257877T3 (es) | 2006-08-01 |
WO2000032207A1 (en) | 2000-06-08 |
JP2002531176A (ja) | 2002-09-24 |
US6479052B1 (en) | 2002-11-12 |
NZ528340A (en) | 2005-07-29 |
EP1143983A1 (de) | 2001-10-17 |
ATE318608T1 (de) | 2006-03-15 |
EP1143983A4 (de) | 2003-05-28 |
DE69930155T2 (de) | 2006-11-23 |
NO20012695D0 (no) | 2001-05-31 |
AU1840200A (en) | 2000-06-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: VIVOLUTION A/S, BIRKEROD, DK |