DE69929792D1 - Mechanismus zur einstellung des tropfenabrisspunktes in einem durchflusszytometer - Google Patents
Mechanismus zur einstellung des tropfenabrisspunktes in einem durchflusszytometerInfo
- Publication number
- DE69929792D1 DE69929792D1 DE69929792T DE69929792T DE69929792D1 DE 69929792 D1 DE69929792 D1 DE 69929792D1 DE 69929792 T DE69929792 T DE 69929792T DE 69929792 T DE69929792 T DE 69929792T DE 69929792 D1 DE69929792 D1 DE 69929792D1
- Authority
- DE
- Germany
- Prior art keywords
- drip
- adjusting
- flow cytometer
- ripping point
- ripping
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
- G01N2015/1406—Control of droplet point
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/119,368 US6079836A (en) | 1998-07-20 | 1998-07-20 | Flow cytometer droplet break-off location adjustment mechanism |
US119368 | 1998-07-20 | ||
PCT/US1999/014284 WO2000005566A1 (en) | 1998-07-20 | 1999-06-25 | Flow cytometer droplet break-off location adjustment mechanism |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69929792D1 true DE69929792D1 (de) | 2006-04-20 |
DE69929792T2 DE69929792T2 (de) | 2006-10-19 |
Family
ID=22384040
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69929792T Expired - Fee Related DE69929792T2 (de) | 1998-07-20 | 1999-06-25 | Mechanismus zur einstellung des tropfenabrisspunktes in einem durchflusszytometer |
Country Status (5)
Country | Link |
---|---|
US (1) | US6079836A (de) |
EP (2) | EP1099105B1 (de) |
JP (1) | JP4426106B2 (de) |
DE (1) | DE69929792T2 (de) |
WO (1) | WO2000005566A1 (de) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2279574C (en) | 1997-01-31 | 2007-07-24 | The Horticulture & Food Research Institute Of New Zealand Ltd. | Optical apparatus |
US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
US6372506B1 (en) * | 1999-07-02 | 2002-04-16 | Becton, Dickinson And Company | Apparatus and method for verifying drop delay in a flow cytometer |
US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
CA2408939C (en) | 2000-05-09 | 2011-11-08 | Xy, Inc. | High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa |
US7016022B2 (en) * | 2000-08-02 | 2006-03-21 | Honeywell International Inc. | Dual use detectors for flow cytometry |
WO2002043486A1 (en) | 2000-11-29 | 2002-06-06 | Xy, Inc. | System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
WO2002092247A1 (en) * | 2001-05-17 | 2002-11-21 | Cytomation, Inc. | Flow cytometer with active automated optical alignment system |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
MXPA05001100A (es) | 2002-08-01 | 2005-04-28 | Xy Inc | Sistema de separacion de baja presion para celulas de esperma. |
US6880414B2 (en) * | 2002-08-08 | 2005-04-19 | Becton Dickinson And Company | Sort block and liquid collection device for sorting flow cytometer |
MXPA05001654A (es) | 2002-08-15 | 2005-10-18 | Xy Inc | Citometro de flujo de alta resolucion. |
US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
US7201875B2 (en) * | 2002-09-27 | 2007-04-10 | Becton Dickinson And Company | Fixed mounted sorting cuvette with user replaceable nozzle |
US6941005B2 (en) * | 2002-11-01 | 2005-09-06 | Coulter International Corp. | Monitoring and control of droplet sorting |
JP3891925B2 (ja) | 2002-12-03 | 2007-03-14 | ベイバイオサイエンス株式会社 | 生物学的粒子の情報を得る装置 |
MX347048B (es) | 2003-03-28 | 2017-04-07 | Inguran Llc * | Aparato de muestreo digital y métodos para separar partículas. |
ES2541121T3 (es) | 2003-05-15 | 2015-07-16 | Xy, Llc | Clasificación eficiente de células haploides por sistemas de citometría de flujo |
CA2561661C (en) | 2004-03-29 | 2015-11-24 | Monsanto Technology Llc | Sperm suspensions for sorting into x or y chromosome-bearing enriched populations |
US7232687B2 (en) * | 2004-04-07 | 2007-06-19 | Beckman Coulter, Inc. | Multiple sorter monitor and control subsystem for flow cytometer |
JP4304120B2 (ja) * | 2004-04-30 | 2009-07-29 | ベイバイオサイエンス株式会社 | 生物学的粒子をソーティングする装置及び方法 |
AR049732A1 (es) | 2004-07-22 | 2006-08-30 | Monsanto Co | Proceso para enriquecer una poblacion de celulas de esperma |
DE202005008763U1 (de) * | 2005-06-02 | 2006-10-19 | Universität Duisburg-Essen | Vorrichtung zum Sortieren von Mikropartikeln, insbesondere biogefährdender und zu schützender Stoffe |
FR2888932A1 (fr) * | 2005-07-19 | 2007-01-26 | Commissariat Energie Atomique | Procede de calibration d'un dispositif de tri en flux de particules |
WO2007056560A2 (en) * | 2005-11-09 | 2007-05-18 | Chemimage Corporation | System and method for cytological analysis by raman spectroscopic imaging |
US7691636B2 (en) * | 2007-05-23 | 2010-04-06 | Beckman Coulter, Inc. | Method and apparatus for compensating for variations in particle trajectories in electrostatic sorter for flowcell cytometer |
US20100098399A1 (en) * | 2008-10-17 | 2010-04-22 | Kurt Breish | High intensity, strobed led micro-strip for microfilm imaging system and methods |
WO2010085632A2 (en) * | 2009-01-23 | 2010-07-29 | University Of Washington | Virtual core flow cytometry |
JP5446563B2 (ja) * | 2009-08-06 | 2014-03-19 | ソニー株式会社 | 微小粒子分取装置、および該微小粒子分取装置を用いたフローサイトメーター |
EP2702133B1 (de) | 2011-04-29 | 2017-08-23 | Becton Dickinson and Company | Zellsortiersystem und -verfahren |
EP2724144B1 (de) * | 2011-08-25 | 2018-04-11 | Sony Corporation | Charakterisierung von bewegungsfehlern in einem strom bewegter mikroeinheiten |
CN104204768B (zh) * | 2012-02-09 | 2018-07-10 | 贝克曼考尔特公司 | 分选流式细胞仪 |
JP5994337B2 (ja) | 2012-03-30 | 2016-09-21 | ソニー株式会社 | 微小粒子分取装置及びディレイタイム決定方法 |
WO2013145905A1 (ja) * | 2012-03-30 | 2013-10-03 | ソニー株式会社 | 微小粒子分取装置及び該装置における流体ストリーム最適化方法 |
JP5924077B2 (ja) | 2012-03-30 | 2016-05-25 | ソニー株式会社 | 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法 |
EP3511694A1 (de) | 2012-03-30 | 2019-07-17 | Sony Corporation | Mikropartikelsortiervorrichtung und verfahren zur positionssteuerung in einer mikropartikelsortiervorrichtung |
WO2014047206A1 (en) | 2012-09-18 | 2014-03-27 | Cytonome/St, Llc | Flow cell for particle sorting |
JP6065527B2 (ja) * | 2012-11-08 | 2017-01-25 | ソニー株式会社 | 微小粒子分取装置及び微小粒子分取方法 |
WO2014115409A1 (ja) | 2013-01-28 | 2014-07-31 | ソニー株式会社 | 微小粒子分取装置、微小粒子分取方法及びプログラム |
WO2014152039A2 (en) * | 2013-03-14 | 2014-09-25 | Cytonome/St, Llc | Operatorless particle processing systems and methods |
EP2984468B1 (de) | 2013-04-12 | 2021-11-17 | Becton, Dickinson and Company | Automatisiertes setup für eine zellsortierung |
CN105579829B (zh) | 2013-08-16 | 2019-02-19 | 生物辐射实验室股份有限公司 | 来自流式细胞器中的流体流的液滴的分离和/或充电的定时和/或相位调整 |
JPWO2015053393A1 (ja) * | 2013-10-10 | 2017-03-09 | 公益財団法人神奈川科学技術アカデミー | イメージングセルソーター |
EP3035030B1 (de) | 2013-10-16 | 2019-07-10 | Sony Corporation | Partikelfraktionierungsvorrichtung, partikelfraktionierungsverfahren und programm |
CN105980831B (zh) | 2014-02-13 | 2021-01-12 | 索尼公司 | 粒子分捡装置、粒子分捡方法、程序以及粒子分捡系统 |
JP6102783B2 (ja) * | 2014-02-14 | 2017-03-29 | ソニー株式会社 | 粒子分取装置、粒子分取方法及びプログラム |
JP6657625B2 (ja) | 2014-09-05 | 2020-03-04 | ソニー株式会社 | 液滴分取装置、液滴分取方法及びプログラム |
WO2017068822A1 (ja) | 2015-10-19 | 2017-04-27 | ソニー株式会社 | 画像処理装置、微小粒子分取装置及び画像処理方法 |
WO2018067209A1 (en) * | 2016-10-05 | 2018-04-12 | Becton, Dickinson And Company | Droplet deflectors and methods for using the same |
US10466158B2 (en) * | 2017-04-11 | 2019-11-05 | Sony Corporation | Microparticle sorting apparatus and delay time determination method |
WO2018216269A1 (ja) * | 2017-05-24 | 2018-11-29 | ソニー株式会社 | 微小粒子の吸引条件の最適化方法及び微小粒子分取装置 |
JP7059747B2 (ja) * | 2018-03-27 | 2022-04-26 | ソニーグループ株式会社 | 微小粒子分取方法、微小粒子分取用プログラム及び微小粒子分取用システム |
EP3785015A4 (de) | 2018-04-27 | 2022-01-19 | Becton, Dickinson and Company | Durchflusszytometer mit eingeschlossenen tröpfchensortierern mit gesteuertem aerosolgehalt und verfahren zur verwendung davon |
US11035776B2 (en) * | 2018-10-30 | 2021-06-15 | Becton, Dickinson And Company | Particle sorting module with alignment window, systems and methods of use thereof |
EP4168774A4 (de) * | 2020-06-19 | 2023-12-27 | Becton, Dickinson and Company | Durchflusszytometer mit einstellbaren positionsversatz-sortierablenkungsplatten und verfahren zur verwendung davon |
CN115916409A (zh) * | 2020-06-24 | 2023-04-04 | 贝克顿·迪金森公司 | 流式细胞术液滴分配系统及使用该系统的方法 |
CN111879685B (zh) * | 2020-07-31 | 2022-03-18 | 上海微电子装备(集团)股份有限公司 | 一种颗粒分析分选装置及充电延时设置方法 |
CN111948118B (zh) * | 2020-08-27 | 2021-12-24 | 上海微电子装备(集团)股份有限公司 | 液滴延时计算装置及其计算方法 |
CN112730408A (zh) * | 2020-12-24 | 2021-04-30 | 贝克曼库尔特生物科技(苏州)有限公司 | 液流检测系统和液流检测方法以及分选装置 |
KR20240032711A (ko) | 2021-03-25 | 2024-03-12 | 이오반스 바이오테라퓨틱스, 인크. | T-세포 공배양 효능 검정 및 세포 치료제와 함께 사용하기 위한 방법 및 조성물 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
US3826364A (en) * | 1972-05-22 | 1974-07-30 | Univ Leland Stanford Junior | Particle sorting method and apparatus |
US3761941A (en) * | 1972-10-13 | 1973-09-25 | Mead Corp | Phase control for a drop generating and charging system |
US3836912A (en) * | 1972-12-11 | 1974-09-17 | Ibm | Drop charge sensing apparatus for an ink jet printing system |
US4025926A (en) * | 1973-01-17 | 1977-05-24 | Sharp Kabushiki Kaisha | Phase synchronization for ink jet system printer |
JPS5421093B2 (de) * | 1973-03-12 | 1979-07-27 | ||
US3878519A (en) * | 1974-01-31 | 1975-04-15 | Ibm | Method and apparatus for synchronizing droplet formation in a liquid stream |
US3963606A (en) * | 1974-06-03 | 1976-06-15 | Coulter Electronics, Inc. | Semi-automatic adjusting delay for an electronic particle separator |
US3982251A (en) * | 1974-08-23 | 1976-09-21 | Ibm Corporation | Method and apparatus for recording information on a recording medium |
US4047143A (en) * | 1976-07-09 | 1977-09-06 | Western Electric Company, Inc. | Fused resistive electrical protection device |
US4045770A (en) * | 1976-11-11 | 1977-08-30 | International Business Machines Corporation | Method and apparatus for adjusting the velocity of ink drops in an ink jet printer |
US4230031A (en) * | 1978-04-26 | 1980-10-28 | Coulter Electronics, Inc. | Biohazard containment apparatus and method |
US4325483A (en) * | 1979-08-20 | 1982-04-20 | Ortho Diagnostics, Inc. | Method for detecting and controlling flow rates of the droplet forming stream of an electrostatic particle sorting apparatus |
US4318480A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device |
US4284496A (en) * | 1979-12-10 | 1981-08-18 | Newton William A | Particle guiding apparatus and method |
US4691829A (en) * | 1980-11-03 | 1987-09-08 | Coulter Corporation | Method of and apparatus for detecting change in the breakoff point in a droplet generation system |
US4361400A (en) * | 1980-11-26 | 1982-11-30 | The United States Of America As Represented By The United States Department Of Energy | Fluidic assembly for an ultra-high-speed chromosome flow sorter |
US5700692A (en) * | 1994-09-27 | 1997-12-23 | Becton Dickinson And Company | Flow sorter with video-regulated droplet spacing |
US5641457A (en) * | 1995-04-25 | 1997-06-24 | Systemix | Sterile flow cytometer and sorter with mechanical isolation between flow chamber and sterile enclosure |
DE19549015C1 (de) * | 1995-12-28 | 1997-04-03 | Siemens Ag | Verfahren und Anordnung zur Überwachung eines abreißenden Flüssigkeitstrahls |
-
1998
- 1998-07-20 US US09/119,368 patent/US6079836A/en not_active Expired - Fee Related
-
1999
- 1999-06-25 WO PCT/US1999/014284 patent/WO2000005566A1/en active IP Right Grant
- 1999-06-25 JP JP2000561483A patent/JP4426106B2/ja not_active Expired - Fee Related
- 1999-06-25 EP EP99931885A patent/EP1099105B1/de not_active Expired - Lifetime
- 1999-06-25 DE DE69929792T patent/DE69929792T2/de not_active Expired - Fee Related
- 1999-06-30 EP EP05014140A patent/EP1602915A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2000005566A1 (en) | 2000-02-03 |
EP1099105B1 (de) | 2006-02-08 |
EP1602915A1 (de) | 2005-12-07 |
DE69929792T2 (de) | 2006-10-19 |
US6079836A (en) | 2000-06-27 |
EP1099105A1 (de) | 2001-05-16 |
JP4426106B2 (ja) | 2010-03-03 |
JP2002521658A (ja) | 2002-07-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69929792D1 (de) | Mechanismus zur einstellung des tropfenabrisspunktes in einem durchflusszytometer | |
DE60025535D1 (de) | Vorrichtung zur bestimmung des durchflusses durch zugeführte volumenänderung | |
DE69939670D1 (de) | Optimalisieren des Prozessablaufs in einem Druckvorbereitungssystem | |
DE69901933T2 (de) | Ventil zur regelung der durchflussmenge | |
DE60013455D1 (de) | System zur erhöhung der flüssigkeitsströmung in einem bohrloch | |
HK1134347A1 (en) | Coriolis mass flow controller | |
FR2785401B1 (fr) | Distributeur regulateur de flux volumique | |
DE60005840D1 (de) | Gerät zur durchflussmessung in einem regler | |
DE69533469D1 (de) | Durchflusszytometer | |
DE69806666T2 (de) | Abstandsbelichtungsvorrichtung mit Vorrichtung zur Einstellung des Abstandes | |
DE69918963D1 (de) | Vorrichtung zur regelung des kühlflüssigkeitsdurchflusses | |
DE69718872T2 (de) | Mehrstufige Vorrichtung zur Durchflussmengenänderung | |
ATA55398A (de) | Vorrichtung zum steuern von fluidströmen beim betanken | |
DE69932203D1 (de) | Trennvorrichtung enthaltend Vorrichtung zur Regelung des Volumenstroms von wenigstens einem Fluid | |
DE69900594T2 (de) | Sensor zur anwendung in metallschmelzen | |
DE59813143D1 (de) | Vorrichtung zur regelung des stromflusses durch einen verbraucher | |
EP1035332A4 (de) | Ventil zum aufteilen des durchflusses | |
DE60112151D1 (de) | System zur Reduziering des Querschnitts in einem Durchflusskanal | |
DE69609728T2 (de) | Vorrichtung zum steuern des mengenflusses in einem leitungssystem | |
FR2779903B1 (fr) | Dispositif securise pour la coupe des vegetaux | |
GB2341660B (en) | Flow control device | |
GB2344364B (en) | Flow control device | |
DE29709860U1 (de) | Vorrichtung zur Durchfluß-Überwachung in Rohrleitungen | |
GB2358696B (en) | Constant flow valve | |
DE29822656U1 (de) | Vorrichtung zur Bestimmung des Durchflußvolumens in einem Kanal |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |