DE69929589D1 - Bioaktive keramische beschichtung - Google Patents

Bioaktive keramische beschichtung

Info

Publication number
DE69929589D1
DE69929589D1 DE69929589T DE69929589T DE69929589D1 DE 69929589 D1 DE69929589 D1 DE 69929589D1 DE 69929589 T DE69929589 T DE 69929589T DE 69929589 T DE69929589 T DE 69929589T DE 69929589 D1 DE69929589 D1 DE 69929589D1
Authority
DE
Germany
Prior art keywords
ceramic coating
bioactive ceramic
bioactive
coating
ceramic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69929589T
Other languages
English (en)
Other versions
DE69929589T2 (de
Inventor
Panjian Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Products Inc
Original Assignee
DePuy Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DePuy Products Inc filed Critical DePuy Products Inc
Application granted granted Critical
Publication of DE69929589D1 publication Critical patent/DE69929589D1/de
Publication of DE69929589T2 publication Critical patent/DE69929589T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
DE69929589T 1998-03-11 1999-03-09 Bioaktive keramische beschichtung Expired - Fee Related DE69929589T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38444 1998-03-11
US09/038,444 US6139585A (en) 1998-03-11 1998-03-11 Bioactive ceramic coating and method
PCT/US1999/005100 WO1999045979A1 (en) 1998-03-11 1999-03-09 Bioactive ceramic coating and method

Publications (2)

Publication Number Publication Date
DE69929589D1 true DE69929589D1 (de) 2006-04-13
DE69929589T2 DE69929589T2 (de) 2006-10-05

Family

ID=21899995

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69929589T Expired - Fee Related DE69929589T2 (de) 1998-03-11 1999-03-09 Bioaktive keramische beschichtung

Country Status (6)

Country Link
US (2) US6139585A (de)
EP (1) EP0984799B1 (de)
JP (1) JP2001525718A (de)
AU (1) AU2991999A (de)
DE (1) DE69929589T2 (de)
WO (1) WO1999045979A1 (de)

Families Citing this family (195)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6607829B1 (en) 1997-11-13 2003-08-19 Massachusetts Institute Of Technology Tellurium-containing nanocrystalline materials
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6736849B2 (en) * 1998-03-11 2004-05-18 Depuy Products, Inc. Surface-mineralized spinal implants
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US6261322B1 (en) 1998-05-14 2001-07-17 Hayes Medical, Inc. Implant with composite coating
US6827742B2 (en) * 1998-05-14 2004-12-07 Daniel E. E. Hayes, Jr. Bimetal acetabular component construct for hip joint prosthesis
DE69906441T2 (de) * 1998-09-15 2004-04-08 Isotis B.V. Beschichtungsverfahren von medizinischen Implantaten
EP0987031B1 (de) * 1998-09-15 2003-04-02 IsoTis N.V. Beschichtungsverfahren von medizinischen Implantaten
US7270705B2 (en) * 1999-07-14 2007-09-18 Jiin-Huey Chern Lin Method of increasing working time of tetracalcium phosphate cement paste
US7169373B2 (en) * 1999-07-14 2007-01-30 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface and process for preparing the same
US6960249B2 (en) * 1999-07-14 2005-11-01 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface
US6840995B2 (en) * 1999-07-14 2005-01-11 Calcitec, Inc. Process for producing fast-setting, bioresorbable calcium phosphate cements
US7094282B2 (en) * 2000-07-13 2006-08-22 Calcitec, Inc. Calcium phosphate cement, use and preparation thereof
EP1251889B1 (de) * 2000-02-04 2003-07-02 IsoTis N.V. Proteinbeschichtung
US7156915B2 (en) * 2000-07-13 2007-01-02 Calcitec, Inc. Tetracalcium phosphate (TTCP) with surface whiskers and method of making same
US7204876B2 (en) * 2000-07-13 2007-04-17 Calcitec, Inc. Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same
WO2002007651A1 (en) 2000-07-20 2002-01-31 Hayes Medical, Inc. Bimetal tibial component construct for knee joint prosthesis
US20060078847A1 (en) * 2000-09-29 2006-04-13 Kwan Norman H Dental implant system and additional methods of attachment
US7207800B1 (en) * 2001-09-28 2007-04-24 Norman Ho-Kwong Kwan Dental implant system and additional methods of attachment
WO2002059395A2 (en) * 2000-12-28 2002-08-01 The Board Of Regents Of The University Of Nebraska Electrolytic deposition of coatings for prosthetic metals and alloys
US20020115742A1 (en) * 2001-02-22 2002-08-22 Trieu Hai H. Bioactive nanocomposites and methods for their use
JP2002322013A (ja) * 2001-04-25 2002-11-08 Univ Nagoya 活性物質の前駆体、該前駆体を用いた活性物質、及びその活性物質の製造方法
US7695521B2 (en) 2001-05-01 2010-04-13 Amedica Corporation Hip prosthesis with monoblock ceramic acetabular cup
US7776085B2 (en) 2001-05-01 2010-08-17 Amedica Corporation Knee prosthesis with ceramic tibial component
EP1408874B1 (de) 2001-06-14 2012-08-08 Amedica Corporation Metall-keramik-verbundgelenk
JP4685277B2 (ja) * 2001-06-20 2011-05-18 独立行政法人物質・材料研究機構 生体組織基体の被覆方法
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
KR20030062812A (ko) * 2002-01-19 2003-07-28 한국과학기술원 금속주대용 플라스틱 자켓을 구비하는 인공보철물장치
US7132015B2 (en) * 2002-02-20 2006-11-07 University Of Southern California Materials for dental and biomedical application
AU2003208639A1 (en) * 2002-02-26 2003-09-09 Hyun-Man Kim Calcium phosphate colloids, dots, islands, thin films or granules and its preparation
US20030216777A1 (en) * 2002-05-16 2003-11-20 Yin-Chun Tien Method of enhancing healing of interfacial gap between bone and tendon or ligament
BR0311971A (pt) 2002-06-20 2005-03-22 Doxa Ab Sistema para produção de um material de obturação dentária ou material de implante, e material em pó, lìquido de hidratação, material de implante e método de obtenção de uma ligação
US7390568B2 (en) 2002-08-13 2008-06-24 Massachusetts Institute Of Technology Semiconductor nanocrystal heterostructures having specific charge carrier confinement
JP2006502232A (ja) * 2002-08-15 2006-01-19 モウンギ ジー． バウエンディ 安定化された半導体ナノクリスタル
AU2003266882A1 (en) * 2002-09-13 2004-04-30 The University Of British Columbia Calcium phosphate coated implantable medical devices and processes for making same
SE0203224D0 (sv) * 2002-10-31 2002-10-31 Cerbio Tech Ab Method of making structured ceramic coatings and coated devices prepared with the method
SE525236C2 (sv) * 2002-10-31 2005-01-11 Cerbio Tech Ab Förfarande för framställning av strukturerade keramiska beläggningar och belagda anordningar framställda med detta förfarande
US7332211B1 (en) 2002-11-07 2008-02-19 Massachusetts Institute Of Technology Layered materials including nanoparticles
US7537664B2 (en) 2002-11-08 2009-05-26 Howmedica Osteonics Corp. Laser-produced porous surface
US20060147332A1 (en) 2004-12-30 2006-07-06 Howmedica Osteonics Corp. Laser-produced porous structure
US20040109947A1 (en) * 2002-12-09 2004-06-10 Weinert Raymond J. Stain resistant coatings for flexible substrates, substrates coated therewith and related methods
WO2004058098A2 (en) 2002-12-17 2004-07-15 Amedica Corporation Total disc implant
US7087086B2 (en) * 2003-01-31 2006-08-08 Depuy Products, Inc. Biological agent-containing ceramic coating and method
US7181266B2 (en) * 2003-03-04 2007-02-20 Massachusetts Institute Of Technology Materials and methods for near-infrared and infrared lymph node mapping
US20050020922A1 (en) * 2003-03-04 2005-01-27 Frangioni John V. Materials and methods for near-infrared and infrared intravascular imaging
US6905723B2 (en) * 2003-05-30 2005-06-14 Depuy Products, Inc. Strontium-substituted apatite coating
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
US8062365B2 (en) * 2003-08-04 2011-11-22 Warsaw Orthopedic, Inc. Bone supporting devices with bio-absorbable end members
US7118705B2 (en) * 2003-08-05 2006-10-10 Calcitec, Inc. Method for making a molded calcium phosphate article
US6994726B2 (en) * 2004-05-25 2006-02-07 Calcitec, Inc. Dual function prosthetic bone implant and method for preparing the same
US7163651B2 (en) * 2004-02-19 2007-01-16 Calcitec, Inc. Method for making a porous calcium phosphate article
JP5419326B2 (ja) * 2003-10-06 2014-02-19 マサチューセッツ インスティテュート オブ テクノロジー 不揮発性メモリデバイス
US20050101964A1 (en) * 2003-11-07 2005-05-12 Calcitec, Inc. Spinal fusion procedure using an injectable bone substitute
JP4199653B2 (ja) * 2003-12-09 2008-12-17 松崎 浩巳 骨補填材
KR100583849B1 (ko) * 2004-01-20 2006-05-26 재단법인서울대학교산학협력재단 인산칼슘 화합물의 폴리메릭 졸 제조방법
ITFI20040048A1 (it) * 2004-02-27 2004-05-27 Menarini Farma Ind Composti biomimetici contenenti idrossiapatiti sostituite con magnesio e carbonato e processi per ottenerli
US20050196519A1 (en) * 2004-03-08 2005-09-08 Depuy Products, Inc. Apparatus for producing a biomimetic coating on a medical implant
DE102004022768A1 (de) * 2004-05-05 2005-12-08 Heraeus Kulzer Gmbh Medizinische Implantate mit glaskeramikartiger Multielement-Oberflächenschicht
US7384430B2 (en) * 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
US7229690B2 (en) * 2004-07-26 2007-06-12 Massachusetts Institute Of Technology Microspheres including nanoparticles
US20080241353A1 (en) * 2004-08-10 2008-10-02 Yekimed Ag Biomimetic Process For Coating Substrates With A Biomimetic Solution Containing A Bioactive Substance And Use Of Said Process And Substrates In Bone, Connective Tissue-, Fat Tissue-And Muscle Tissue Engineering
US8329202B2 (en) 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
US7312989B2 (en) * 2004-12-06 2007-12-25 Chenbro Micom Co., Ltd. Cooler
WO2006062518A2 (en) 2004-12-08 2006-06-15 Interpore Spine Ltd. Continuous phase composite for musculoskeletal repair
US8535357B2 (en) 2004-12-09 2013-09-17 Biomet Sports Medicine, Llc Continuous phase compositions for ACL repair
US7879275B2 (en) 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
DE102004063794A1 (de) * 2004-12-30 2006-07-13 Universität Duisburg-Essen Implantat
US7896921B2 (en) 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7883653B2 (en) 2004-12-30 2011-02-08 Depuy Products, Inc. Method of making an implantable orthopaedic bearing
US7998219B2 (en) * 2005-01-04 2011-08-16 Rutgers, The State University Of New Jersey Hydroxyapatite with controllable size and morphology
US8815328B2 (en) 2005-01-04 2014-08-26 Rutgers, The State University Of New Jersey Hydroxyapatite with controllable size and morphology
AU2006200043B2 (en) * 2005-01-07 2011-11-17 Inframat Corporation Coated medical devices and methods of making and using
US20060216327A1 (en) * 2005-03-28 2006-09-28 Bacterin, Inc. Multilayer coating for releasing biologically-active agents and method of making
US7740794B1 (en) 2005-04-18 2010-06-22 Biomet Sports Medicine, Llc Methods of making a polymer and ceramic composite
US7727589B2 (en) 2005-04-22 2010-06-01 Tetsuya Suzuki Method of producing esthetically pleasing ornaments from bone components
US9119901B2 (en) * 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
US8414907B2 (en) * 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US20060257492A1 (en) * 2005-05-13 2006-11-16 Depuy Products, Inc. Suspension of calcium phosphate particulates for local delivery of therapeutic agents
US20060257358A1 (en) * 2005-05-13 2006-11-16 Depuy Products, Inc. Suspension of calcium phosphate particulates for local delivery of therapeutic agents
US7531190B2 (en) * 2005-05-25 2009-05-12 Biomet Manufacturing Corp. Porous ceramic structure containing biologics
US8845927B2 (en) 2006-06-02 2014-09-30 Qd Vision, Inc. Functionalized nanoparticles and method
US7537789B1 (en) 2005-07-15 2009-05-26 Envirovest Llc System controlling soluble phosphorus and nitrates and other nutrients, and a method of using the system
US20070055147A1 (en) * 2005-09-06 2007-03-08 Honeywell International Inc. Medical devices incorporating radio-opaque and biocompatible coatings
ES2726355T3 (es) 2005-11-14 2019-10-03 Biomet 3I Llc Deposición de nanopartículas discretas en una superficie de implante
US8728387B2 (en) * 2005-12-06 2014-05-20 Howmedica Osteonics Corp. Laser-produced porous surface
US7394094B2 (en) * 2005-12-29 2008-07-01 Massachusetts Institute Of Technology Semiconductor nanocrystal heterostructures
EP1803513B1 (de) * 2005-12-30 2017-03-29 Howmedica Osteonics Corp. Herstellungsverfahren von Implantaten mittels Laser
WO2008079152A2 (en) * 2006-01-04 2008-07-03 University Of Connecticut Ceramic coating and method of preparation thereof
US20070156249A1 (en) * 2006-01-05 2007-07-05 Howmedica Osteonics Corp. High velocity spray technique for medical implant components
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US20100040668A1 (en) * 2006-01-12 2010-02-18 Rutgers, The State University Of New Jersey Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US8252058B2 (en) 2006-02-16 2012-08-28 Amedica Corporation Spinal implant with elliptical articulatory interface
WO2008070028A2 (en) * 2006-12-01 2008-06-12 Qd Vision, Inc. Improved composites and devices including nanoparticles
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
EP2007317A2 (de) * 2006-04-05 2008-12-31 University Of Nebraska Rekonstruierter knochen aus bioresorbierbarem polymer und herstellungsverfahren dafür
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US20070288021A1 (en) * 2006-06-07 2007-12-13 Howmedica Osteonics Corp. Flexible joint implant
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
JP2009542359A (ja) 2006-06-29 2009-12-03 ボストン サイエンティフィック リミテッド 選択的被覆部を備えた医療装置
DE102006033152A1 (de) * 2006-07-18 2008-01-31 Chemische Fabrik Budenheim Kg Nanofeine Phosphate
WO2008016712A2 (en) * 2006-08-02 2008-02-07 Inframat Corporation Medical devices and methods of making and using
CN101588826A (zh) * 2006-08-02 2009-11-25 英孚拉玛特公司 腔支撑装置及其制造及使用方法
US8052743B2 (en) 2006-08-02 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis with three-dimensional disintegration control
US8147861B2 (en) 2006-08-15 2012-04-03 Howmedica Osteonics Corp. Antimicrobial implant
WO2008033388A2 (en) * 2006-09-12 2008-03-20 Qd Vision, Inc. A composite including nanoparticles, methods, and products including a composite
EP2068757B1 (de) 2006-09-14 2011-05-11 Boston Scientific Limited Medizinprodukte mit wirkstofffreisetzender beschichtung
CA2663220A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
JP2010503491A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生物学的安定性無機層を有する生浸食性エンドプロスシーシス
EP2081616B1 (de) 2006-09-15 2017-11-01 Boston Scientific Scimed, Inc. Bioerodierbare endoprothesen und herstellungsverfahren dafür
EP2068782B1 (de) 2006-09-15 2011-07-27 Boston Scientific Limited Biologisch erodierbare endoprothesen
US8002821B2 (en) 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
US20080097618A1 (en) * 2006-10-18 2008-04-24 Kevin Charles Baker Deposition of calcium-phosphate (CaP) and calcium-phosphate with bone morphogenic protein (CaP+BMP) coatings on metallic and polymeric surfaces
ES2729425T3 (es) 2006-10-24 2019-11-04 Biomet 3I Llc Deposición de nanopartículas discretas sobre una superficie nanoestructurada de un implante
US7981150B2 (en) * 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
DE602007010669D1 (de) 2006-12-28 2010-12-30 Boston Scient Ltd Hren dafür
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US7771775B2 (en) * 2007-03-26 2010-08-10 Howmedica Osteonics Corp. Method for fabricating a medical component from a material having a high carbide phase
US8920534B2 (en) 2007-03-26 2014-12-30 Howmedica Osteonics Corp. Method for fabricating a biocompatible material having a high carbide phase and such material
US8057914B2 (en) * 2007-03-26 2011-11-15 Howmedica Osteonics Corp. Method for fabricating a medical component from a material having a high carbide phase and such medical component
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
JP2010533563A (ja) 2007-07-19 2010-10-28 ボストン サイエンティフィック リミテッド 吸着抑制表面を有する内部人工器官
WO2009014718A1 (en) 2007-07-24 2009-01-29 Porex Corporation Porous laser sintered articles
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8221822B2 (en) 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (ja) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド 広い表面積を有する医療器具用のコーティング
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
WO2009097218A1 (en) 2008-01-28 2009-08-06 Biomet 3I, Llc Implant surface with increased hydrophilicity
US8920491B2 (en) 2008-04-22 2014-12-30 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8449603B2 (en) 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
WO2010101901A2 (en) 2009-03-02 2010-09-10 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8696759B2 (en) 2009-04-15 2014-04-15 DePuy Synthes Products, LLC Methods and devices for implants with calcium phosphate
US20100268227A1 (en) * 2009-04-15 2010-10-21 Depuy Products, Inc. Methods and Devices for Bone Attachment
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
SE535536C2 (sv) * 2009-04-27 2012-09-11 Biomatcell Ab Jonsubstituerade hydroxiapatitytbeläggningar
US20110076396A1 (en) * 2009-09-28 2011-03-31 Limin Guan Method of forming a calcium phosphate coating within a porous material
ES2606042T3 (es) * 2009-10-29 2017-03-17 Prosidyan, Inc. Material de injerto óseo bioactivo dinámico y métodos para su manipulación
ES2672590T3 (es) 2009-10-29 2018-06-15 Prosidyan, Inc. Material dinámico de injerto óseo bioactivo que tiene una porosidad diseñada
US8475536B2 (en) * 2010-01-29 2013-07-02 DePuy Synthes Products, LLC Methods and devices for implants with improved cement adhesion
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
US9248020B2 (en) * 2010-11-17 2016-02-02 Zimmer, Inc. Ceramic monoblock implants with osseointegration fixation surfaces
US10369253B2 (en) * 2011-10-31 2019-08-06 The University Of Toledo Method for modifying surfaces for better osseointegration
US9364896B2 (en) 2012-02-07 2016-06-14 Medical Modeling Inc. Fabrication of hybrid solid-porous medical implantable devices with electron beam melting technology
WO2013142118A1 (en) 2012-03-20 2013-09-26 Biomet 3I, Llc Surface treatment for an implant surface
WO2013142763A1 (en) 2012-03-22 2013-09-26 University Of Connecticut Biomimetic scaffold for bone regeneration
US9135374B2 (en) 2012-04-06 2015-09-15 Howmedica Osteonics Corp. Surface modified unit cell lattice structures for optimized secure freeform fabrication
US9180010B2 (en) 2012-04-06 2015-11-10 Howmedica Osteonics Corp. Surface modified unit cell lattice structures for optimized secure freeform fabrication
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US10980919B2 (en) 2016-04-14 2021-04-20 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US10376845B2 (en) 2016-04-14 2019-08-13 Lockheed Martin Corporation Membranes with tunable selectivity
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US9592475B2 (en) 2013-03-12 2017-03-14 Lockheed Martin Corporation Method for forming perforated graphene with uniform aperture size
US8889178B2 (en) 2013-03-14 2014-11-18 Prosidyan, Inc Bioactive porous bone graft compositions in synthetic containment
US8883195B2 (en) 2013-03-14 2014-11-11 Prosidyan, Inc. Bioactive porous bone graft implants
US9381274B2 (en) 2013-03-14 2016-07-05 Prosidyan, Inc. Bone graft implants containing allograft
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
EP3100297A4 (de) 2014-01-31 2017-12-13 Lockheed Martin Corporation Perforierung von zweidimensionalen materialien mit einem breiten ionenfeld
SG11201606287VA (en) 2014-01-31 2016-08-30 Lockheed Corp Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer
JP2017512129A (ja) 2014-03-12 2017-05-18 ロッキード・マーチン・コーポレーション 有孔グラフェンから形成された分離膜
WO2016036888A1 (en) 2014-09-02 2016-03-10 Lockheed Martin Corporation Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
JP2018528144A (ja) 2015-08-05 2018-09-27 ロッキード・マーチン・コーポレーション グラフェン系材料の穿孔可能なシート
MX2018001559A (es) 2015-08-06 2018-09-27 Lockheed Corp Modificacion de nanoparticula y perforacion de grafeno.
JP2019519756A (ja) 2016-04-14 2019-07-11 ロッキード・マーチン・コーポレーション 欠陥形成または欠陥修復をその場で監視して制御する方法
JP2019517909A (ja) 2016-04-14 2019-06-27 ロッキード・マーチン・コーポレーション 流路を有する二次元膜構造体
EP3442739A4 (de) 2016-04-14 2020-03-04 Lockheed Martin Corporation Verfahren zur behandlung von graphenfolien für grossflächigen transfer mittels free-float-verfahren
JP2019521055A (ja) 2016-04-14 2019-07-25 ロッキード・マーチン・コーポレーション グラフェン欠陥の選択的界面緩和
CN108324578B (zh) * 2017-01-17 2020-02-14 武汉大学 一种液相矿化前驱体及修复脱矿牙本质的方法
JP6783465B2 (ja) * 2017-01-19 2020-11-11 国立研究開発法人物質・材料研究機構 医療用生体吸収性部材とその製造方法
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
US11298747B2 (en) 2017-05-18 2022-04-12 Howmedica Osteonics Corp. High fatigue strength porous structure
RU2680149C2 (ru) * 2017-06-20 2019-02-18 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) Способ получения биоактивного покрытия на основе кремнийзамещенного гидроксиапатита
CN108295307A (zh) * 2018-03-02 2018-07-20 中国医科大学附属口腔医院 一种骨植入用钙磷化合物-镁复合涂层及其制备方法
EP4210922A1 (de) 2020-09-11 2023-07-19 Happe Spine LLC Verfahren zur herstellung einer implantierbaren medizinischen vorrichtung mit unterschiedlicher zusammensetzung und porosität

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285223A (en) * 1979-02-12 1981-08-25 Narayan Das Phosphate and ester coating method
US5178845A (en) * 1988-04-20 1993-01-12 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
US5962028A (en) * 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US4880610A (en) * 1988-04-20 1989-11-14 Norian Corporation In situ calcium phosphate minerals--method and composition
JPH0629126B2 (ja) * 1989-03-29 1994-04-20 京都大学長 生体活性水酸アパタイト膜のコーティング法
JP2858126B2 (ja) * 1989-06-30 1999-02-17 京セラ株式会社 生体インプラント材とその製法
JP2830262B2 (ja) * 1990-01-08 1998-12-02 住友化学工業株式会社 ハイドロキシアパタイト皮膜の形成方法
US5188670A (en) * 1990-04-05 1993-02-23 Norian Corporation Apparatus for hydroxyapatite coatings of substrates
US5164187A (en) * 1990-04-05 1992-11-17 Norian Corporation Hydroxyapatite prosthesis coatings
JP2657847B2 (ja) * 1990-05-10 1997-09-30 寅雄 大塚 水酸化アパタイト多孔質生体充▲てん▼材並びにその製造方法
US5702448A (en) * 1990-09-17 1997-12-30 Buechel; Frederick F. Prosthesis with biologically inert wear resistant surface
US5231169A (en) * 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
JP3198125B2 (ja) * 1991-06-18 2001-08-13 株式会社アドバンス インプラントの製造方法
FI91713C (fi) * 1992-04-23 1994-08-10 Axidental Oy Uusia bioaktiivisia pinnotteita ja niiden valmistus ja käyttö
US5545226A (en) * 1992-05-29 1996-08-13 Porex Technologies Corp. Implants for cranioplasty
CA2167721A1 (en) * 1993-07-22 1995-02-02 Mark Fulmer Storage stable partially neutralized acid compositions and uses
US5763092A (en) * 1993-09-15 1998-06-09 Etex Corporation Hydroxyapatite coatings and a method of their manufacture
GB9407135D0 (en) * 1994-04-11 1994-06-01 Aberdeen University And Plasma Treatment of osteoporosis
JP2590439B2 (ja) * 1994-07-27 1997-03-12 工業技術院長 水酸アパタイトの被膜の形成法
US5496399A (en) * 1994-08-23 1996-03-05 Norian Corporation Storage stable calcium phosphate cements
DE4431862C2 (de) * 1994-09-07 1997-12-11 Dot Duennschicht Und Oberflaec Verfahren zur Beschichtung von Metall- und Keramikoberflächen mit Hydroxylapatit
US5569442A (en) * 1994-11-04 1996-10-29 Norian Corporation Reactive tricalcium phosphate compositions and uses
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US5817326A (en) * 1995-12-01 1998-10-06 The Regents Of The University Of California Processing of hydroxylapatite coatings on titanium alloy bone prostheses
IT1288038B1 (it) * 1996-04-30 1998-09-10 Flametal S P A Procedimento per la preparazione di rivestimenti di idrossiapatite
US6143948A (en) * 1996-05-10 2000-11-07 Isotis B.V. Device for incorporation and release of biologically active agents
ATE220565T1 (de) * 1996-12-23 2002-08-15 Stiftung Robert Mathys H C Dr Bioaktive oberflächenschicht für knochenimplantate
US5958430A (en) * 1998-02-20 1999-09-28 Battelle Memorial Institute Thin film composition with biological substance and method of making
DE69906441T2 (de) * 1998-09-15 2004-04-08 Isotis B.V. Beschichtungsverfahren von medizinischen Implantaten

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