DE69929019D1 - Mu-1, ein mitglied der zytokinrezeptor-familie - Google Patents
Mu-1, ein mitglied der zytokinrezeptor-familieInfo
- Publication number
- DE69929019D1 DE69929019D1 DE69929019T DE69929019T DE69929019D1 DE 69929019 D1 DE69929019 D1 DE 69929019D1 DE 69929019 T DE69929019 T DE 69929019T DE 69929019 T DE69929019 T DE 69929019T DE 69929019 D1 DE69929019 D1 DE 69929019D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor family
- cytokin
- cytokin receptor
- disclosed
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40005 | 1993-04-09 | ||
US09/040,005 US6057128A (en) | 1998-03-17 | 1998-03-17 | MU-1, member of the cytokine receptor family |
PCT/US1999/005854 WO1999047675A1 (en) | 1998-03-17 | 1999-03-17 | Mu-1, member of the cytokine receptor family |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69929019D1 true DE69929019D1 (de) | 2006-01-26 |
DE69929019T2 DE69929019T2 (de) | 2006-08-03 |
Family
ID=21908554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69929019T Expired - Lifetime DE69929019T2 (de) | 1998-03-17 | 1999-03-17 | Mu-1, ein mitglied der zytokinrezeptor-familie |
Country Status (9)
Country | Link |
---|---|
US (3) | US6057128A (de) |
EP (4) | EP1681348A1 (de) |
JP (3) | JP2001527423A (de) |
AT (1) | ATE313626T1 (de) |
AU (1) | AU758824B2 (de) |
DE (1) | DE69929019T2 (de) |
DK (1) | DK0994947T3 (de) |
ES (1) | ES2253879T3 (de) |
WO (1) | WO1999047675A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7198789B2 (en) * | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
US6057128A (en) * | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
US7189400B2 (en) | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
CA2330547A1 (en) * | 1998-06-24 | 1999-12-29 | Chugai Research Institute For Molecular Medicine, Inc. | Novel hemopoietin receptor proteins |
WO2000008152A1 (en) * | 1998-08-04 | 2000-02-17 | Regeneron Pharmaceuticals, Inc. | Novel orphan cytokine receptors |
AU2004203069B2 (en) * | 1998-09-23 | 2008-06-12 | Zymogenetics Inc. | Cytokine Receptor Zalpha11 |
DE69941126D1 (de) * | 1998-09-23 | 2009-08-27 | Zymogenetics Inc | Cytokinerezeptor zalpha11 |
US6803451B2 (en) | 1998-09-23 | 2004-10-12 | Zymogenetics, Inc. | Cytokine receptor zalpha11 polypeptides |
US6576744B1 (en) * | 1998-09-23 | 2003-06-10 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
US6307024B1 (en) * | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
PL207350B1 (pl) * | 1999-03-09 | 2010-12-31 | Zymogenetics Inc | Izolowany polipeptyd, cząsteczka izolowanego polinukleotydu, komórka, sposób wykrywania obecności RNA liganda zalpha11, sposób wykrywania obecności polipeptydu, przeciwciało, zastosowanie kompozycji zawierającej polipeptyd, zastosowanie polipeptydu do rozprzestrzeniania komórek krwiotwórczych, zastosowanie polipeptydu do wytwarzania leku i polipeptyd do zastosowania w medycynie |
WO2000069880A1 (en) * | 1999-05-18 | 2000-11-23 | Millennium Pharmaceuticals, Inc. | Il-9/il-2 receptor-like molecules and uses thereof |
US20020090680A1 (en) * | 1999-05-18 | 2002-07-11 | Millennium Pharmaceuticals, Inc. | Novel IL-9/IL-2 receptor-like molecules and uses thereof |
DK1749888T3 (da) | 2000-04-05 | 2010-05-10 | Zymogenetics Inc | Opløselige Zalph11a-cytokinreceptorer |
JP2004500845A (ja) * | 2000-05-11 | 2004-01-15 | ジェネティクス インスティテュート,エルエルシー | サイトカインレセプターファミリーのメンバーであるmu−1 |
WO2003028630A2 (en) * | 2001-10-04 | 2003-04-10 | Genetics Institute Llc. | Methods and compositions for modulating interleukin-21 receptor activity |
US20040016010A1 (en) * | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
WO2003103589A2 (en) * | 2002-06-07 | 2003-12-18 | Zymogenetics, Inc. | Use of il-21 in cancer and other therapeutic applications |
JP4776228B2 (ja) * | 2002-07-15 | 2011-09-21 | ワイス・エルエルシー | Tヘルパー(th)細胞の発生および機能を調節するための方法および組成物 |
US20070092485A1 (en) * | 2002-11-15 | 2007-04-26 | Zymogenetics, Inc. | Cytokine zalpha11 ligand |
JP4664684B2 (ja) | 2002-12-13 | 2011-04-06 | ザイモジェネティクス, インコーポレイテッド | 原核生物宿主におけるil−21の生産 |
ATE456581T1 (de) * | 2003-03-14 | 2010-02-15 | Wyeth Corp | Antikörper gegen il21-rezeptor und deren verwendung |
CN1849131A (zh) * | 2003-03-21 | 2006-10-18 | Wyeth公司 | 用白介素-21/白介素-21受体的激动剂治疗免疫性疾病 |
CA2538083A1 (en) * | 2003-09-25 | 2005-04-07 | Zymogenetics, Inc. | Methods of treating autoimmune diseases using il-21 |
JP4982373B2 (ja) * | 2004-05-20 | 2012-07-25 | ザイモジェネティクス, インコーポレイテッド | Il−21およびモノクローナル抗体治療を用いる癌を処置する方法 |
US20070111941A1 (en) * | 2004-06-09 | 2007-05-17 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
BRPI0514138A (pt) * | 2004-08-05 | 2008-05-27 | Wyeth Corp | método para tratar, melhorar, ou prevenir um distúrbio, proteìna de fusão, vetor, célula hospedeira recombinante, método para produzir uma proteìna de fusão, composição farmacêutica, e, métodos para transplantar/enxertar um órgão, tecido, célula ou grupo de células em um indivìduo mamìfero, e para tratar, prevenir ou melhorar rejeição de transplante/enxerto em um receptor de transplante/enxerto mamìfero |
GT200600148A (es) * | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
EP1960433A2 (de) * | 2005-11-28 | 2008-08-27 | Zymogenetics, Inc. | Il-21 rezeptor antagonisten |
PT1963369E (pt) * | 2005-11-28 | 2013-05-28 | Zymogenetics Inc | Antagonistas de il-21 |
JP5745274B2 (ja) | 2007-12-07 | 2015-07-08 | ザイモジェネティクス, インコーポレイテッド | 抗ヒトil−21モノクローナル抗体 |
US8178097B2 (en) * | 2008-05-23 | 2012-05-15 | Wyeth Llc | Methods of treatment utilizing binding proteins of the interleukin-21 receptor |
PE20100141A1 (es) * | 2008-05-23 | 2010-02-22 | Wyeth Corp | Proteina de union al receptor de interleuquina 21 |
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US7198789B2 (en) | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
US7189400B2 (en) | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
US6057128A (en) | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
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US6803451B2 (en) | 1998-09-23 | 2004-10-12 | Zymogenetics, Inc. | Cytokine receptor zalpha11 polypeptides |
DE69941126D1 (de) | 1998-09-23 | 2009-08-27 | Zymogenetics Inc | Cytokinerezeptor zalpha11 |
US6576744B1 (en) | 1998-09-23 | 2003-06-10 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
WO2000027882A1 (en) | 1998-11-06 | 2000-05-18 | Smithkline Beecham Corporation | Hnovilr |
PL207350B1 (pl) | 1999-03-09 | 2010-12-31 | Zymogenetics Inc | Izolowany polipeptyd, cząsteczka izolowanego polinukleotydu, komórka, sposób wykrywania obecności RNA liganda zalpha11, sposób wykrywania obecności polipeptydu, przeciwciało, zastosowanie kompozycji zawierającej polipeptyd, zastosowanie polipeptydu do rozprzestrzeniania komórek krwiotwórczych, zastosowanie polipeptydu do wytwarzania leku i polipeptyd do zastosowania w medycynie |
US6307024B1 (en) | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
WO2000069880A1 (en) | 1999-05-18 | 2000-11-23 | Millennium Pharmaceuticals, Inc. | Il-9/il-2 receptor-like molecules and uses thereof |
US20020090680A1 (en) | 1999-05-18 | 2002-07-11 | Millennium Pharmaceuticals, Inc. | Novel IL-9/IL-2 receptor-like molecules and uses thereof |
CA2392109A1 (en) | 1999-11-18 | 2001-05-25 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
ATE459369T1 (de) | 1999-12-23 | 2010-03-15 | Zymogenetics Inc | Verfahren zur behandlung von entzündungen |
DK1749888T3 (da) | 2000-04-05 | 2010-05-10 | Zymogenetics Inc | Opløselige Zalph11a-cytokinreceptorer |
DE10019727A1 (de) * | 2000-04-20 | 2001-10-25 | Alcatel Sa | Netzwerkserver |
JP2004500845A (ja) | 2000-05-11 | 2004-01-15 | ジェネティクス インスティテュート,エルエルシー | サイトカインレセプターファミリーのメンバーであるmu−1 |
JP2002157737A (ja) * | 2000-05-12 | 2002-05-31 | Tdk Corp | 光記録方法および光記録媒体 |
US6680563B2 (en) * | 2001-06-27 | 2004-01-20 | Thomson Licensing S.A. | Color picture tube having a low expansion tension mask attached to a higher expansion frame |
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JP4776228B2 (ja) | 2002-07-15 | 2011-09-21 | ワイス・エルエルシー | Tヘルパー(th)細胞の発生および機能を調節するための方法および組成物 |
ATE456581T1 (de) | 2003-03-14 | 2010-02-15 | Wyeth Corp | Antikörper gegen il21-rezeptor und deren verwendung |
CN1849131A (zh) | 2003-03-21 | 2006-10-18 | Wyeth公司 | 用白介素-21/白介素-21受体的激动剂治疗免疫性疾病 |
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BRPI0514138A (pt) | 2004-08-05 | 2008-05-27 | Wyeth Corp | método para tratar, melhorar, ou prevenir um distúrbio, proteìna de fusão, vetor, célula hospedeira recombinante, método para produzir uma proteìna de fusão, composição farmacêutica, e, métodos para transplantar/enxertar um órgão, tecido, célula ou grupo de células em um indivìduo mamìfero, e para tratar, prevenir ou melhorar rejeição de transplante/enxerto em um receptor de transplante/enxerto mamìfero |
GT200600148A (es) | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
WO2009100035A2 (en) | 2008-02-01 | 2009-08-13 | Wyeth | Interleukin-21 (il-21) and il-21 receptor (il-21r) modulation of regulatory t cells and forkhead box p3 (foxp3) |
PE20100141A1 (es) | 2008-05-23 | 2010-02-22 | Wyeth Corp | Proteina de union al receptor de interleuquina 21 |
US8178097B2 (en) | 2008-05-23 | 2012-05-15 | Wyeth Llc | Methods of treatment utilizing binding proteins of the interleukin-21 receptor |
-
1998
- 1998-03-17 US US09/040,005 patent/US6057128A/en not_active Expired - Lifetime
-
1999
- 1999-03-17 AT AT99911454T patent/ATE313626T1/de active
- 1999-03-17 ES ES99911454T patent/ES2253879T3/es not_active Expired - Lifetime
- 1999-03-17 JP JP54728399A patent/JP2001527423A/ja not_active Withdrawn
- 1999-03-17 DE DE69929019T patent/DE69929019T2/de not_active Expired - Lifetime
- 1999-03-17 WO PCT/US1999/005854 patent/WO1999047675A1/en active IP Right Grant
- 1999-03-17 EP EP05112429A patent/EP1681348A1/de not_active Withdrawn
- 1999-03-17 DK DK99911454T patent/DK0994947T3/da active
- 1999-03-17 AU AU30093/99A patent/AU758824B2/en not_active Ceased
- 1999-03-17 EP EP10167168A patent/EP2228448A1/de not_active Withdrawn
- 1999-03-17 EP EP99911454A patent/EP0994947B1/de not_active Expired - Lifetime
- 1999-03-17 EP EP05112423A patent/EP1688495A1/de not_active Withdrawn
-
2007
- 2007-12-17 US US11/957,891 patent/US7705123B2/en not_active Expired - Fee Related
-
2009
- 2009-10-02 JP JP2009230370A patent/JP2010057489A/ja active Pending
-
2010
- 2010-01-28 US US12/695,485 patent/US7994292B2/en not_active Expired - Fee Related
-
2013
- 2013-04-25 JP JP2013093025A patent/JP2013188214A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ES2253879T3 (es) | 2006-06-01 |
AU3009399A (en) | 1999-10-11 |
ATE313626T1 (de) | 2006-01-15 |
EP0994947B1 (de) | 2005-12-21 |
JP2001527423A (ja) | 2001-12-25 |
EP2228448A1 (de) | 2010-09-15 |
US20080167241A1 (en) | 2008-07-10 |
EP0994947A1 (de) | 2000-04-26 |
DE69929019T2 (de) | 2006-08-03 |
JP2010057489A (ja) | 2010-03-18 |
US20100130729A1 (en) | 2010-05-27 |
US7994292B2 (en) | 2011-08-09 |
DK0994947T3 (da) | 2006-04-18 |
EP1681348A1 (de) | 2006-07-19 |
AU758824B2 (en) | 2003-04-03 |
US6057128A (en) | 2000-05-02 |
US7705123B2 (en) | 2010-04-27 |
EP1688495A1 (de) | 2006-08-09 |
WO1999047675A1 (en) | 1999-09-23 |
JP2013188214A (ja) | 2013-09-26 |
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