DE69925722D1 - Auf stimuli reagierendes gel enthaltend ein radioisotop und verfahren zur herstellung - Google Patents
Auf stimuli reagierendes gel enthaltend ein radioisotop und verfahren zur herstellungInfo
- Publication number
- DE69925722D1 DE69925722D1 DE69925722T DE69925722T DE69925722D1 DE 69925722 D1 DE69925722 D1 DE 69925722D1 DE 69925722 T DE69925722 T DE 69925722T DE 69925722 T DE69925722 T DE 69925722T DE 69925722 D1 DE69925722 D1 DE 69925722D1
- Authority
- DE
- Germany
- Prior art keywords
- gelling
- stimulus
- copolymer
- sensitive
- reversible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1213—Semi-solid forms, gels, hydrogels, ointments, fats and waxes that are solid at room temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/058,712 US6296831B1 (en) | 1998-04-10 | 1998-04-10 | Stimulus sensitive gel with radioisotope and methods of making |
US58712 | 1998-04-10 | ||
PCT/US1999/007662 WO1999055386A2 (en) | 1998-04-10 | 1999-04-06 | Stimulus sensitive gel with radioisotope and methods of making |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69925722D1 true DE69925722D1 (de) | 2005-07-14 |
DE69925722T2 DE69925722T2 (de) | 2005-12-15 |
Family
ID=22018452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69925722T Expired - Fee Related DE69925722T2 (de) | 1998-04-10 | 1999-04-06 | Auf stimuli reagierendes gel enthaltend ein radioisotop und verfahren zur herstellung |
Country Status (9)
Country | Link |
---|---|
US (2) | US6296831B1 (de) |
EP (1) | EP1069919B1 (de) |
JP (1) | JP2002512987A (de) |
AT (1) | ATE297224T1 (de) |
AU (1) | AU752477B2 (de) |
CA (1) | CA2327325C (de) |
DE (1) | DE69925722T2 (de) |
NZ (1) | NZ507174A (de) |
WO (1) | WO1999055386A2 (de) |
Families Citing this family (54)
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CA2291622C (en) * | 1997-06-06 | 2007-09-04 | Anna Gutowska | Reversible geling co-polymer and method of making |
US6296831B1 (en) * | 1998-04-10 | 2001-10-02 | Battelle Memorial Institute | Stimulus sensitive gel with radioisotope and methods of making |
US7087244B2 (en) | 2000-09-28 | 2006-08-08 | Battelle Memorial Institute | Thermogelling oligopeptide polymers |
US20040228794A1 (en) * | 1998-04-10 | 2004-11-18 | Battelle Memorial Institute | Therapeutic agent carrier compositions |
US20030176663A1 (en) * | 1998-05-11 | 2003-09-18 | Eidgenossische Technische Hochscule | Specific binding molecules for scintigraphy |
GB9905048D0 (en) * | 1999-03-05 | 1999-04-28 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
DE19953636A1 (de) * | 1999-11-09 | 2001-05-23 | Karlsruhe Forschzent | Radioaktive Materialien |
AU2001242432B2 (en) * | 2000-02-24 | 2007-11-08 | Eidgenossische Technische Hochschule Zurich | Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis |
US6660247B1 (en) * | 2000-06-23 | 2003-12-09 | Battelle Memorial Institute | Multiple stimulus reversible hydrogels |
CN1246333C (zh) * | 2000-09-07 | 2006-03-22 | 舍林股份公司 | EDb-纤粘连蛋白结构域(II)的受体 |
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FR2824832B1 (fr) * | 2001-05-16 | 2005-05-27 | Oreal | Polymeres hydrosolubles a squelette hydrosoluble et a unites laterales a lcst, leur procede de preparation, compositions aqueuses les contenant, et leur utilisation dans le domaine cosmetique |
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WO2004098523A2 (en) * | 2003-04-30 | 2004-11-18 | The Board Of Trustees At The University Of Illinois At Chicago | Intraocular brachytherapy device and method |
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US20060067883A1 (en) * | 2004-09-24 | 2006-03-30 | Biosphere Medical, Inc. | Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof |
PT1909855T (pt) * | 2005-07-26 | 2018-06-11 | Aplha Tau Medical Ltd | Uma fonte de superfície radioativa e um método para produzir a mesma |
US20080038190A1 (en) * | 2006-08-11 | 2008-02-14 | Simpson Thomas J | Composition apparatus and method for use in imaging |
CA2661389C (en) * | 2006-09-07 | 2016-04-12 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treating bone cancer |
EP1985286A1 (de) * | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Mikrokügelchen zur Behandlung von Gehirntumoren |
US8480651B2 (en) * | 2007-08-02 | 2013-07-09 | Covidien Lp | Cannula system |
CA2709712C (en) | 2007-12-20 | 2016-05-10 | Surmodics Pharmaceuticals, Inc. | Process for preparing microparticles having a low residual solvent volume |
US8253725B2 (en) * | 2007-12-28 | 2012-08-28 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method and system for generating surface models of geometric structures |
US8608632B1 (en) | 2009-07-03 | 2013-12-17 | Salutaris Medical Devices, Inc. | Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye |
DK2227257T3 (da) | 2008-01-07 | 2013-09-30 | Salutaris Medical Devices Inc | Anordninger til minimal-invasiv ekstraokular afgivelse af stråling til den posteriore del af øjet |
US8821364B2 (en) * | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
FR2939666B1 (fr) | 2008-12-17 | 2012-11-30 | Irsn | Formulations cosmetiques et pharmaceutiques de molecules de calix[6]arenes |
US8663210B2 (en) * | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
KR20120102598A (ko) * | 2009-09-17 | 2012-09-18 | 에보닉 데구사 코포레이션 | 방출 프로파일에 따라 변하는 임플란트 장치 및 이를 제조하고 사용하는 방법 |
US20110091518A1 (en) * | 2009-09-22 | 2011-04-21 | Danielle Biggs | Implant devices having varying bioactive agent loading configurations |
CN104470547B (zh) * | 2012-05-24 | 2018-01-26 | 未来化学株式会社 | 利用筒状物合成放射性药物的方法 |
NL2009688C2 (en) * | 2012-10-24 | 2014-04-29 | Nucletron Operations Bv | A settable radioactive gel, a method of manufacturing a settable radioactive gel, a device for manufacturing a settable radioactive gel. |
CN105263477B (zh) | 2013-03-13 | 2019-01-15 | 生物领域医疗公司 | 用于放射性同位素结合微粒的组合物和相关方法 |
US9899133B2 (en) | 2013-08-01 | 2018-02-20 | Qorvo Us, Inc. | Advanced 3D inductor structures with confined magnetic field |
US10392611B2 (en) | 2013-05-30 | 2019-08-27 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
US10364451B2 (en) | 2013-05-30 | 2019-07-30 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
CN103736201B (zh) * | 2013-12-31 | 2016-01-20 | 原子高科股份有限公司 | 一种放射性粒子链 |
CN104147688A (zh) * | 2014-07-31 | 2014-11-19 | 吉林大学 | 一种快速成型自适应近距离后装施源器及其制作方法 |
US10385115B2 (en) | 2015-03-26 | 2019-08-20 | Duke University | Fibronectin type III domain-based fusion proteins |
MX2018001511A (es) | 2015-08-04 | 2018-08-01 | Univ Duke | Polimeros furtivos desordenados de forma intrinseca codificados geneticamente para suministro y metodos para usar los mismos. |
US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
US11467156B2 (en) | 2016-06-01 | 2022-10-11 | Duke University | Nonfouling biosensors |
WO2018053201A1 (en) | 2016-09-14 | 2018-03-22 | Duke University | Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs |
EP3515928A4 (de) | 2016-09-23 | 2020-04-01 | Duke University | Unstrukturierte nichtrepititive polypeptide mit lcst-verhalten |
WO2018132732A1 (en) | 2017-01-12 | 2018-07-19 | Duke University | Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly |
EP3573595A1 (de) * | 2017-01-24 | 2019-12-04 | Maria Desantis | Zusammensetzung, vorrichtung und verfahren zur konformationellen intragewebe-beta-brachytherapie |
WO2018213320A1 (en) | 2017-05-15 | 2018-11-22 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
EP3658168A4 (de) | 2017-06-30 | 2021-07-14 | Duke University | Ordnung und unordnung als designprinzip für auf stimuli ansprechende biopolymernetzwerke |
WO2020028806A1 (en) | 2018-08-02 | 2020-02-06 | Duke University | Dual agonist fusion proteins |
US11478557B2 (en) * | 2019-07-01 | 2022-10-25 | Vivos, Inc. | Method of preparing a radioactive yttrium phosphate particle suspension |
US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
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CA980022A (en) | 1972-05-15 | 1975-12-16 | Douglas Whitfield | Remotely controlled brachytherapy unit |
US4190461A (en) | 1978-03-20 | 1980-02-26 | Alpha-Omega Services, Inc. | Method for removing metallic seeds from nylon tubing used in interstitial brachytherapy |
US4510924A (en) | 1980-07-10 | 1985-04-16 | Yale-New Haven Hospital, Inc. | Brachytherapy devices and methods employing americium-241 |
US4754745A (en) | 1984-11-21 | 1988-07-05 | Horowitz Bruce S | Conformable sheet material for use in brachytherapy |
US5322499A (en) | 1985-09-20 | 1994-06-21 | Liprie Sam F | Continuous sheated low dose radioactive core adapted for cutting into short sealed segments |
US4763642A (en) | 1986-04-07 | 1988-08-16 | Horowitz Bruce S | Intracavitational brachytherapy |
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USH669H (en) | 1986-12-08 | 1989-09-05 | The United States Of America As Represented By The United States Department Of Energy | Samarium-145 and its use as a radiation source |
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CA2131032A1 (en) | 1992-02-28 | 1993-09-02 | Stanley E. Order | Use of aggregated proteins to prolong retention time of a therapeutic agent adjacent a targeted site such as a tumor |
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CA2291622C (en) | 1997-06-06 | 2007-09-04 | Anna Gutowska | Reversible geling co-polymer and method of making |
US6015541A (en) | 1997-11-03 | 2000-01-18 | Micro Therapeutics, Inc. | Radioactive embolizing compositions |
US6296831B1 (en) * | 1998-04-10 | 2001-10-02 | Battelle Memorial Institute | Stimulus sensitive gel with radioisotope and methods of making |
US6296837B1 (en) * | 2000-03-14 | 2001-10-02 | Ting-Chun Tsai | Fragrant fingernail polish |
-
1998
- 1998-04-10 US US09/058,712 patent/US6296831B1/en not_active Expired - Lifetime
-
1999
- 1999-04-06 JP JP2000545582A patent/JP2002512987A/ja active Pending
- 1999-04-06 AU AU53118/99A patent/AU752477B2/en not_active Ceased
- 1999-04-06 DE DE69925722T patent/DE69925722T2/de not_active Expired - Fee Related
- 1999-04-06 NZ NZ507174A patent/NZ507174A/en unknown
- 1999-04-06 AT AT99938691T patent/ATE297224T1/de not_active IP Right Cessation
- 1999-04-06 EP EP99938691A patent/EP1069919B1/de not_active Expired - Lifetime
- 1999-04-06 CA CA002327325A patent/CA2327325C/en not_active Expired - Lifetime
- 1999-04-06 WO PCT/US1999/007662 patent/WO1999055386A2/en active IP Right Grant
-
2001
- 2001-05-09 US US09/853,507 patent/US6869588B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69925722T2 (de) | 2005-12-15 |
US6296831B1 (en) | 2001-10-02 |
WO1999055386A3 (en) | 2000-06-29 |
US6869588B2 (en) | 2005-03-22 |
AU752477B2 (en) | 2002-09-19 |
JP2002512987A (ja) | 2002-05-08 |
WO1999055386A2 (en) | 1999-11-04 |
CA2327325C (en) | 2006-01-24 |
AU5311899A (en) | 1999-11-16 |
US20010024636A1 (en) | 2001-09-27 |
EP1069919A2 (de) | 2001-01-24 |
EP1069919B1 (de) | 2005-06-08 |
NZ507174A (en) | 2003-11-28 |
CA2327325A1 (en) | 1999-11-04 |
ATE297224T1 (de) | 2005-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |