DE69904344D1 - Mikrofluidisches reaktions- und transfersystem - Google Patents

Mikrofluidisches reaktions- und transfersystem

Info

Publication number
DE69904344D1
DE69904344D1 DE69904344T DE69904344T DE69904344D1 DE 69904344 D1 DE69904344 D1 DE 69904344D1 DE 69904344 T DE69904344 T DE 69904344T DE 69904344 T DE69904344 T DE 69904344T DE 69904344 D1 DE69904344 D1 DE 69904344D1
Authority
DE
Germany
Prior art keywords
chambers
duct
tab
transfer system
microfluidic reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69904344T
Other languages
English (en)
Other versions
DE69904344T2 (de
Inventor
Bruno Colin
Cecile Paris
Jacques Dachaud
Pierre Imbaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9811383A external-priority patent/FR2782934B1/fr
Application filed by Biomerieux SA filed Critical Biomerieux SA
Application granted granted Critical
Publication of DE69904344D1 publication Critical patent/DE69904344D1/de
Publication of DE69904344T2 publication Critical patent/DE69904344T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0015Diaphragm or membrane valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0023Constructional types of microvalves; Details of the cutting-off member with ball-shaped valve members
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0605Valves, specific forms thereof check valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0638Valves, specific forms thereof with moving parts membrane valves, flap valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K2099/0071Microvalves with latching means
DE69904344T 1998-09-08 1999-09-08 Mikrofluidisches reaktions- und transfersystem Expired - Lifetime DE69904344T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR9811383A FR2782934B1 (fr) 1998-09-08 1998-09-08 Dispositif permettant des reactions, systeme de transfert entre dispositifs et procede de mise en oeuvre d'un tel systeme
FR9811383 1998-09-08
FR9907689A FR2782935B3 (fr) 1998-09-08 1999-06-14 Dispositif permettant des reactions, systeme de transfert entre dispositifs et procede de mise en oeuvre d'un tel systeme
FR9907689 1999-06-14
PCT/FR1999/002137 WO2000013795A1 (fr) 1998-09-08 1999-09-08 Systeme microfluidique de reactions et de transfert

Publications (2)

Publication Number Publication Date
DE69904344D1 true DE69904344D1 (de) 2003-01-16
DE69904344T2 DE69904344T2 (de) 2004-04-08

Family

ID=26234541

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69904344T Expired - Lifetime DE69904344T2 (de) 1998-09-08 1999-09-08 Mikrofluidisches reaktions- und transfersystem

Country Status (10)

Country Link
US (1) US6929239B1 (de)
EP (2) EP1112122B1 (de)
JP (1) JP2003525101A (de)
AT (1) ATE228885T1 (de)
AU (1) AU747591B2 (de)
CA (1) CA2342735C (de)
DE (1) DE69904344T2 (de)
ES (1) ES2189469T3 (de)
FR (1) FR2782935B3 (de)
WO (1) WO2000013795A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2795518B1 (fr) 1999-06-22 2001-12-21 Biomerieux Sa Dispositif de mise en oeuvre d'une carte d'analyse, carte d'analyse et procede les mettant en oeuvre
FR2806009B1 (fr) 2000-03-07 2002-05-31 Bio Merieux Procede de mise en oeuvre d'une carte d'analyse
FR2813207B1 (fr) * 2000-08-28 2002-10-11 Bio Merieux Carte reactionnelle et utilisation d'une telle carte
MXPA03003396A (es) * 2000-10-18 2004-12-13 Clarity Technologies Inc Metodo y dispositivo para diluir un fluido y detectar analitos dentro de un fluido diluido.
FR2817604B1 (fr) 2000-12-01 2004-04-23 Biomerieux Sa Vannes activees par des polymeres electro-actifs ou par des materiaux a memoire de forme, dispositif contenant de telles vannes et procede de mise en oeuvre
WO2002070932A2 (en) * 2001-03-07 2002-09-12 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Microvalve
JP2003094395A (ja) * 2001-09-26 2003-04-03 Olympus Optical Co Ltd アレイ化マイクロ流体素子
US7867193B2 (en) * 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
US7198759B2 (en) * 2002-07-26 2007-04-03 Applera Corporation Microfluidic devices, methods, and systems
FR2857427B1 (fr) 2003-07-10 2005-08-26 Biomerieux Sa Vanne a commande electrique comprenant une membrane microporeuse
JP4208820B2 (ja) 2003-11-28 2009-01-14 株式会社東芝 核酸検出カセット
US7867194B2 (en) 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
CA2583406A1 (en) * 2004-09-20 2007-01-04 Boston Microfluidics Microfluidic device for detecting soluble molecules
CN101500709A (zh) * 2006-05-01 2009-08-05 皇家飞利浦电子股份有限公司 用于加工、控制和/或检测流体样品并有减小的死体积的流体样品输送装置
US7794665B2 (en) * 2006-07-17 2010-09-14 Industrial Technology Research Institute Fluidic device
US7959876B2 (en) * 2006-07-17 2011-06-14 Industrial Technology Research Institute Fluidic device
US20080021364A1 (en) * 2006-07-17 2008-01-24 Industrial Technology Research Institute Fluidic device
US7897113B2 (en) * 2006-07-17 2011-03-01 Industrial Technology Research Institute Fluidic devices and controlling methods thereof
WO2008094672A2 (en) 2007-01-31 2008-08-07 Charles Stark Draper Laboratory, Inc. Membrane-based fluid control in microfluidic devices
CN101458249B (zh) * 2007-12-14 2013-09-11 东莞博识生物科技有限公司 一种具有溶液储室兼泵体结构的微流体样品舟
JP5311356B2 (ja) * 2009-09-04 2013-10-09 国立大学法人北陸先端科学技術大学院大学 有核赤血球濃縮回収用チップ及び有核赤血球濃縮回収方法
WO2011082276A1 (en) * 2009-12-31 2011-07-07 General Electric Company Microvalve
US8876795B2 (en) 2011-02-02 2014-11-04 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
FR2973720B1 (fr) * 2011-04-08 2016-02-26 Commissariat Energie Atomique Dispositif de connexion d'une carte microfluidique
US8740177B2 (en) * 2011-07-05 2014-06-03 Rain Bird Corporation Eccentric diaphragm valve
US10865440B2 (en) * 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
EP2679307B1 (de) * 2012-06-28 2015-08-12 Thinxxs Microtechnology Ag Mikrospeicher, insbesondere zur Integration in eine mikrofluidische Flusszelle
GB2516675A (en) * 2013-07-29 2015-02-04 Atlas Genetics Ltd A valve which depressurises, and a valve system
GB2516671A (en) * 2013-07-29 2015-02-04 Atlas Genetics Ltd A valve which actuates and latches
KR101638941B1 (ko) 2014-09-15 2016-07-12 울산과학기술원 미세 유동 장치 및 미세 유동 장치의 제어설비
KR102233127B1 (ko) * 2014-10-14 2021-03-26 엘지디스플레이 주식회사 가이드 패널 및 이를 포함한 액정 표시 장치
GB2541202B (en) * 2015-08-11 2021-06-23 Agilent Technologies Inc Stacked layer-type member with integrated functional component
EP3367105A4 (de) 2015-10-23 2019-05-15 Japan Science and Technology Agency Nano-fluid-vorrichtung und chemische analysevorrichtung
WO2018065100A1 (en) * 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Cartridge for testing an in particular biological sample
KR101997837B1 (ko) * 2017-10-27 2019-07-08 울산과학기술원 미세 유동 장치 및 미세 유동 장치의 제어설비
EP4273430A1 (de) * 2020-12-31 2023-11-08 Everlast Healthcare Limited Kolbenmechanismus, fluidsteuerungsmechanismus und anwendung davon

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US40939A (en) * 1863-12-15 Improvement in faucets
US155034A (en) * 1874-09-15 Improvement in valves
US3613729A (en) * 1970-02-16 1971-10-19 Packard Instrument Co Inc Valve system
US3680830A (en) * 1971-01-05 1972-08-01 Nasa Evacuation valve
US3881513A (en) 1974-01-25 1975-05-06 Sun Oil Co Pennsylvania Three-coordinate fluid manifold
US4006753A (en) * 1975-07-30 1977-02-08 Recognition Equipment Incorporated Rotary disc valve
US4106675A (en) 1976-12-22 1978-08-15 The Kendall Company Liquid sampling device
US4585623A (en) 1984-02-27 1986-04-29 Allelix Inc. Device for performing quantitative chemical and immunochemical assays
US5188148A (en) * 1990-12-21 1993-02-23 Millipore Corporation Conduit plate for fluid delivery system
US5165655A (en) * 1991-07-12 1992-11-24 Dxl Usa Flow control valve assembly minimizing generation and entrapment of contaminants
US5325880A (en) * 1993-04-19 1994-07-05 Tini Alloy Company Shape memory alloy film actuated microvalve
DE4438785C2 (de) * 1994-10-24 1996-11-07 Wita Gmbh Wittmann Inst Of Tec Mikrochemische Reaktions- und Analyseeinheit
US5772181A (en) 1995-06-01 1998-06-30 Emerson Electric Co. Pivoting valve assembly
US5671905A (en) * 1995-06-21 1997-09-30 Hopkins, Jr.; Dean A. Electrochemical actuator and method of making same
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
DE19648730C2 (de) * 1996-11-25 1998-11-19 Fraunhofer Ges Forschung Piezoelektrisch betätigtes Mikroventil
US5771914A (en) * 1997-02-13 1998-06-30 Baxter International Inc. Flexible fluid junction
US5989499A (en) * 1997-05-02 1999-11-23 Biomerieux, Inc. Dual chamber disposable reaction vessel for amplification reactions
US5961925A (en) * 1997-09-22 1999-10-05 Bristol-Myers Squibb Company Apparatus for synthesis of multiple organic compounds with pinch valve block

Also Published As

Publication number Publication date
ATE228885T1 (de) 2002-12-15
DE69904344T2 (de) 2004-04-08
EP1112122B1 (de) 2002-12-04
EP1201305A2 (de) 2002-05-02
EP1201305A3 (de) 2002-11-13
AU747591B2 (en) 2002-05-16
US6929239B1 (en) 2005-08-16
ES2189469T3 (es) 2003-07-01
AU5522999A (en) 2000-03-27
JP2003525101A (ja) 2003-08-26
FR2782935B3 (fr) 2000-10-20
CA2342735C (fr) 2009-04-21
EP1112122A1 (de) 2001-07-04
FR2782935A1 (fr) 2000-03-10
CA2342735A1 (fr) 2000-03-16
WO2000013795A1 (fr) 2000-03-16

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted