DE69839357D1 - Verfahren und Reagenzien zur Erzeugung einer CD8+ T-Zellen Immunantwort gegen Melanoma - Google Patents

Verfahren und Reagenzien zur Erzeugung einer CD8+ T-Zellen Immunantwort gegen Melanoma

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Publication number
DE69839357D1
DE69839357D1 DE69839357T DE69839357T DE69839357D1 DE 69839357 D1 DE69839357 D1 DE 69839357D1 DE 69839357 T DE69839357 T DE 69839357T DE 69839357 T DE69839357 T DE 69839357T DE 69839357 D1 DE69839357 D1 DE 69839357D1
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Germany
Prior art keywords
reagents
immune response
response against
cell immune
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69839357T
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English (en)
Other versions
DE69839357T2 (de
Inventor
Andrew James Mcmichael
Magdalena Plebanski
Tom Blanchard
Tomas Hanke
Joerg Schneider
Sarah Catherine Gilbert
Adrian Vivian Sinton Hill
Geoffrey Lilley Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxxon Therapeutics Ltd
Original Assignee
Oxxon Therapeutics Ltd
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Application filed by Oxxon Therapeutics Ltd filed Critical Oxxon Therapeutics Ltd
Publication of DE69839357D1 publication Critical patent/DE69839357D1/de
Application granted granted Critical
Publication of DE69839357T2 publication Critical patent/DE69839357T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/5258—Virus-like particles
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    • A61K2039/53—DNA (RNA) vaccination
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    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69839357T 1997-06-09 1998-06-09 Verfahren und Reagenzien zur Erzeugung einer CD8+ T-Zellen Immunantwort gegen Melanoma Expired - Lifetime DE69839357T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711957.2A GB9711957D0 (en) 1997-06-09 1997-06-09 Methods and reagents for vaccination
GB9711957 1997-06-09

Publications (2)

Publication Number Publication Date
DE69839357D1 true DE69839357D1 (de) 2008-05-21
DE69839357T2 DE69839357T2 (de) 2009-07-02

Family

ID=10813841

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69810459T Expired - Lifetime DE69810459T3 (de) 1997-06-09 1998-06-09 Reagenzien zur impfung, die eine cd8 t-zell-immunantwort erzeugen
DE69839359T Expired - Lifetime DE69839359T2 (de) 1997-06-09 1998-06-09 Verfahren und Reagenzien zur Erzeugung einer CD8+T-Zellen Immunantwort gegen Hepatitis B oder C
DE69839405T Expired - Lifetime DE69839405T2 (de) 1997-06-09 1998-06-09 Verfahren und Reagenzien zur Erzeugung einer CD8+ T-Zellen Immunantwort
DE69839357T Expired - Lifetime DE69839357T2 (de) 1997-06-09 1998-06-09 Verfahren und Reagenzien zur Erzeugung einer CD8+ T-Zellen Immunantwort gegen Melanoma

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DE69810459T Expired - Lifetime DE69810459T3 (de) 1997-06-09 1998-06-09 Reagenzien zur impfung, die eine cd8 t-zell-immunantwort erzeugen
DE69839359T Expired - Lifetime DE69839359T2 (de) 1997-06-09 1998-06-09 Verfahren und Reagenzien zur Erzeugung einer CD8+T-Zellen Immunantwort gegen Hepatitis B oder C
DE69839405T Expired - Lifetime DE69839405T2 (de) 1997-06-09 1998-06-09 Verfahren und Reagenzien zur Erzeugung einer CD8+ T-Zellen Immunantwort

Country Status (12)

Country Link
US (10) US6663871B1 (de)
EP (5) EP1335023B1 (de)
JP (2) JP4282095B2 (de)
CN (1) CN100379865C (de)
AT (4) ATE391783T1 (de)
AU (1) AU737780B2 (de)
CA (1) CA2293692C (de)
DE (4) DE69810459T3 (de)
DK (2) DK1335023T3 (de)
ES (1) ES2189185T5 (de)
GB (1) GB9711957D0 (de)
WO (1) WO1998056919A2 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9711957D0 (en) * 1997-06-09 1997-08-06 Isis Innovation Methods and reagents for vaccination
US20030138454A1 (en) * 1997-06-09 2003-07-24 Oxxon Pharmaccines, Ltd. Vaccination method
GB0023203D0 (en) * 2000-09-21 2000-11-01 Isis Innovation Vaccination method
EP1078092B1 (de) * 1998-05-13 2011-08-03 Epimmune Inc. Expressionsvektoren zur stimulierung einer immunantwort und verfahren zu deren verwendung
SI1117421T1 (en) * 1998-10-05 2004-12-31 Pharamexa A/S Methods for therapeutic vaccination
EP1117421B2 (de) 1998-10-05 2014-03-19 Bavarian Nordic Inc. Verfahren zur therapeutischen impfung
US7148035B1 (en) 1998-11-18 2006-12-12 Oxford Biomedica (Uk) Limited Polypeptide
WO2000044410A2 (en) * 1999-01-28 2000-08-03 Stichting Biomedical Primate Research Centre Composition and method for obtaining specific immunisation against one or more antigens using different recombinant vectors
CA2372709C (en) 1999-05-28 2011-10-25 Stefan Wintersperger Vector for integration of heterologous sequences into poxviral genomes
WO2001002607A1 (en) 1999-07-06 2001-01-11 Merck & Co., Inc. Adenovirus carrying gag gene hiv vaccine
EP1808180A3 (de) 1999-10-22 2010-12-22 Sanofi Pasteur Limited Modifiziertes GP 100 und Verwendung dafür
DE60043856D1 (de) * 1999-12-23 2010-04-01 Medical Res Council Verbesserungen in oder in bezug auf immunantworten gegen hiv
ES2288885T3 (es) * 1999-12-28 2008-02-01 Pharmexa Inc. Minigenes optimizados y peptidos codificados por los mismos.
US8623379B2 (en) 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
US20020106798A1 (en) 2000-03-02 2002-08-08 Robinson Harriet L. DNA expression vectors and methods of use
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