DE69838614D1 - Antiadhäsivbioresorbierbarkomplexe von polyethern und carboxypolysacchariden und verfahren zu ihrer verwendung für die verminderung postchirurgischer verklebung - Google Patents

Antiadhäsivbioresorbierbarkomplexe von polyethern und carboxypolysacchariden und verfahren zu ihrer verwendung für die verminderung postchirurgischer verklebung

Info

Publication number
DE69838614D1
DE69838614D1 DE69838614T DE69838614T DE69838614D1 DE 69838614 D1 DE69838614 D1 DE 69838614D1 DE 69838614 T DE69838614 T DE 69838614T DE 69838614 T DE69838614 T DE 69838614T DE 69838614 D1 DE69838614 D1 DE 69838614D1
Authority
DE
Germany
Prior art keywords
membranes
compositions
bioadhesive
surgical
adhesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69838614T
Other languages
English (en)
Other versions
DE69838614T2 (de
Inventor
Herbert E Schwartz
John M Blackmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FzioMed Inc
Original Assignee
FzioMed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FzioMed Inc filed Critical FzioMed Inc
Publication of DE69838614D1 publication Critical patent/DE69838614D1/de
Application granted granted Critical
Publication of DE69838614T2 publication Critical patent/DE69838614T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
DE69838614T 1997-06-17 1998-05-28 Zusammensetzungen von Carboxypolysaccharid-Polyetherkomplexen zur Verwendung zum Vermindern chirurgischer Verwachsungen Expired - Lifetime DE69838614T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US877649 1997-06-17
US08/877,649 US5906997A (en) 1997-06-17 1997-06-17 Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
PCT/US1998/010814 WO1998058011A1 (en) 1997-06-17 1998-05-28 Bioresorbable antiadhesion of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions

Publications (2)

Publication Number Publication Date
DE69838614D1 true DE69838614D1 (de) 2007-12-06
DE69838614T2 DE69838614T2 (de) 2008-08-28

Family

ID=25370416

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69838614T Expired - Lifetime DE69838614T2 (de) 1997-06-17 1998-05-28 Zusammensetzungen von Carboxypolysaccharid-Polyetherkomplexen zur Verwendung zum Vermindern chirurgischer Verwachsungen

Country Status (9)

Country Link
US (4) US5906997A (de)
EP (1) EP1002002B1 (de)
JP (1) JP4986311B2 (de)
KR (1) KR100612975B1 (de)
AT (1) ATE376567T1 (de)
AU (1) AU754787B2 (de)
CA (1) CA2294200C (de)
DE (1) DE69838614T2 (de)
WO (1) WO1998058011A1 (de)

Families Citing this family (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7009034B2 (en) * 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US20090324721A1 (en) * 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
US8003705B2 (en) * 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US20040096422A1 (en) * 1997-06-17 2004-05-20 Schwartz Herbert E. Compositions of polyacids and polyethers and methods for their use in reducing pain
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US6872384B1 (en) 1998-02-23 2005-03-29 Life Medical Sciences, Inc. Treatment of trauma
EP0967227A1 (de) * 1998-06-04 1999-12-29 Mitsubishi Gas Chemical Company, Inc. Verfahren zur Herstellung von Carboxypolysaccharid
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US7347850B2 (en) * 1998-08-14 2008-03-25 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
JP2002531217A (ja) * 1998-12-04 2002-09-24 チャンドラシェカー ピー． パサック， 生体適合性架橋ポリマー
US20080114092A1 (en) * 1998-12-04 2008-05-15 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
KR20020000143A (ko) 1999-02-23 2002-01-04 페어슨 메디칼 인크. 외상의 치료
FR2791262B1 (fr) * 1999-03-22 2001-09-28 Virbac Sa Compositions a base de chondroitine et de chitosan pour la protection, le traitement ou le remplacement des tissus conjonctifs
CA2366880C (en) * 1999-04-02 2013-02-12 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US7514097B1 (en) * 1999-11-09 2009-04-07 Denki Kagaku Kogyo Kabushiki Kaisha Use of soluble cellulose derivative having been made hardly soluble in water and process for producing the same
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
US7592017B2 (en) 2000-03-10 2009-09-22 Mast Biosurgery Ag Resorbable thin membranes
KR20030031480A (ko) * 2000-04-28 2003-04-21 프지오메드, 인코포레이티드 폴리산 및 폴리알킬렌 옥사이드의 지혈 조성물 및 이들의이용 방법
US6478803B1 (en) 2000-05-19 2002-11-12 Genzyme Corporation Device for delivery of surgical materials
KR20010107067A (ko) * 2000-05-25 2001-12-07 김정식 유착방지제
US6235796B1 (en) 2000-06-26 2001-05-22 Sarfaraz K. Niazi Use of fluorocarbons for the prevention of surgical adhesions
JP2004507237A (ja) * 2000-08-21 2004-03-11 ライスユニバーシティ マトリクスタンパク質の産生を促進する組織工学足場
US20030007951A1 (en) * 2000-08-23 2003-01-09 Richard Franklin Treatment of trauma
US20020177680A1 (en) * 2000-08-23 2002-11-28 Hubbell Jeffrey A. Novel polymer compounds
US6773723B1 (en) * 2000-08-30 2004-08-10 Depuy Acromed, Inc. Collagen/polysaccharide bilayer matrix
US6726920B1 (en) 2000-09-22 2004-04-27 Durect Corporation Implantable drug delivery patch
AU1538702A (en) * 2000-10-24 2002-05-06 Cryolife Inc In situ bioprosthetic filler and methods, particularly for the in situ formationof vertebral disc bioprosthetics
WO2002085284A2 (en) * 2000-11-07 2002-10-31 Cryolife, Inc. Expandable foam-like biomaterials and methods
US7074424B2 (en) 2000-11-28 2006-07-11 Genzyme Corporation Polyalkylene glycol viscosity-enhancing polymeric formulations
US6607512B2 (en) 2001-01-09 2003-08-19 Genzyme Corporation Device for delivery of liquid and gel-like surgical materials and methods for use thereof
US7615593B2 (en) * 2001-04-23 2009-11-10 Wisconsin Alumni Research Foundation Bifunctional-modified hydrogels
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
WO2003007784A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
US7163563B2 (en) * 2001-07-16 2007-01-16 Depuy Products, Inc. Unitary surgical device and method
WO2003007839A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Devices form naturally occurring biologically derived
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
WO2003007790A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
JP4197157B2 (ja) * 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 軟骨修復再生装置および方法
WO2003020208A2 (en) * 2001-08-31 2003-03-13 Neuron Therapeutics, Inc. Treatment of neurologic hemorrhage
FR2833268B1 (fr) * 2001-12-12 2005-07-08 Fabre Pierre Dermo Cosmetique Nouvelle association contenant un poloxamer et de l'acide chondroitine sulfurique et/ou une glycoproteine et son utilisation
WO2003071986A2 (en) * 2002-02-22 2003-09-04 Control Delivery Systems, Inc. Method for treating otic disorders
CA2419831A1 (en) * 2002-02-28 2003-08-28 Macropore Biosurgery, Inc. Methods for governing bone growth
US6923961B2 (en) 2002-04-30 2005-08-02 Fziomed, Inc. Chemically activated carboxypolysaccharides and methods for use to inhibit adhesion formation and promote hemostasis
CA2494203C (en) * 2002-07-31 2012-01-03 Macropore Biosurgery, Inc. Resorbable thin membranes
EP1545389B1 (de) * 2002-07-31 2020-04-22 Mast Biosurgery AG Gerät zur prävention von adhäsionen zwischen einem implantat und dem umgebenden gewebe
US8048444B2 (en) * 2002-07-31 2011-11-01 Mast Biosurgery Ag Apparatus and method for preventing adhesions between an implant and surrounding tissues
CA2495818A1 (en) * 2002-08-20 2004-03-04 John N. Semertzides Compositions comprising epithelial cells for the treatment and prevention of tissue adhesions
US7438925B2 (en) * 2002-08-26 2008-10-21 Biovention Holdings Ltd. Drug eluting coatings for medical implants
US7704520B1 (en) 2002-09-10 2010-04-27 Mast Biosurgery Ag Methods of promoting enhanced healing of tissues after cardiac surgery
US20060083767A1 (en) * 2003-02-27 2006-04-20 Kai Deusch Surgical prosthesis having biodegradable and nonbiodegradable regions
US20070020314A1 (en) * 2003-06-30 2007-01-25 Hirotaka Haro Adhesion inhibiting material for vertebral/spinal operation
US20100266663A1 (en) * 2003-09-10 2010-10-21 Calhoun Christopher J Tissue-treating implantable compositions
US9066912B2 (en) * 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
US7332179B2 (en) * 2003-12-12 2008-02-19 Kimberly-Clark Worldwide, Inc. Tissue products comprising a cleansing composition
US7114074B2 (en) * 2003-12-22 2006-09-26 Graphic Security Systems Corporation Method and system for controlling encoded image production using image signatures
US8277831B2 (en) * 2004-02-17 2012-10-02 Advanced Technologies And Regenerative Medicine, Llc. Drug-enhanced adhesion prevention
US7737214B2 (en) * 2004-03-15 2010-06-15 Terumo Kabushiki Kaisha Adhesion preventive material
DE102004014633A1 (de) * 2004-03-22 2005-10-13 Aesculap Ag & Co. Kg Zusammensetzung zur Adhäsionsprophylaxe
US20050244480A1 (en) * 2004-04-30 2005-11-03 Kimberly-Clark Worldwide, Inc. Pre-wipes for improving anal cleansing
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US7758654B2 (en) * 2004-05-20 2010-07-20 Kensey Nash Corporation Anti-adhesion device
CN101018512B (zh) * 2004-08-13 2011-05-18 马斯特生物外科股份公司 具有可生物降解区和不可生物降解区的外科手术假体
US20080091277A1 (en) * 2004-08-13 2008-04-17 Kai Deusch Surgical prosthesis having biodegradable and nonbiodegradable regions
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US20060140899A1 (en) * 2004-12-28 2006-06-29 Kimberly-Clark Worldwide, Inc. Skin cleansing system comprising an anti-adherent formulation and a cationic compound
US7642395B2 (en) * 2004-12-28 2010-01-05 Kimberly-Clark Worldwide, Inc. Composition and wipe for reducing viscosity of viscoelastic bodily fluids
EP1879606B1 (de) 2005-04-25 2013-06-12 Massachusetts Institute of Technology Selbstorganisierende Peptide zur Förderung der Hämostase
US8414907B2 (en) 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US9119901B2 (en) * 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
ES2387195T3 (es) * 2005-05-27 2012-09-17 Royer Biomedical, Inc. Matrices de polímero y métodos de fabricación y uso de las mismas
EP1911769B1 (de) 2005-08-04 2013-10-30 Teijin Limited Cellulosederivat
US20080119878A1 (en) * 2005-08-12 2008-05-22 Kai Deusch Surgical prosthesis having biodegradable and nonbiodegradable regions
FR2895907B1 (fr) * 2006-01-06 2012-06-01 Anteis Sa Gel viscoelastique a usage dermatologique
CN100434123C (zh) * 2006-02-23 2008-11-19 暨南大学 琼脂和胶原多孔防粘连膜及其制备方法
EP1996115B1 (de) * 2006-03-07 2014-11-26 Axle International Bioaktives gerüst für therapeutische und haftverhinderungsanwendungen
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
KR20110091019A (ko) 2006-04-25 2011-08-10 메사추세츠 인스티튜트 오브 테크놀로지 오염물, 체액 또는 다른 실재물의 이동 및/또는 다른 생리학적 상태에 영향을 주기 위한 조성물 및 방법
US20080082170A1 (en) * 2006-09-29 2008-04-03 Peterman Marc M Apparatus and methods for surgical repair
US8114159B2 (en) * 2006-11-20 2012-02-14 Depuy Spine, Inc. Anterior spinal vessel protector
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US8067028B2 (en) * 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
US8486467B1 (en) * 2007-09-20 2013-07-16 Albert G. Prescott Dermal filler and method of using same
US9345809B2 (en) 2007-11-28 2016-05-24 Fziomed, Inc. Carboxymethylcellulose polyethylene glycol compositions for medical uses
US8668863B2 (en) * 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US8745133B2 (en) * 2008-03-28 2014-06-03 Yahoo! Inc. System and method for optimizing the storage of data
US8932622B2 (en) * 2008-06-03 2015-01-13 Actamax Surgical Materials, Llc Tissue coating for preventing undesired tissue-to-tissue adhesions
WO2010040131A2 (en) * 2008-10-03 2010-04-08 Replication Medical, Inc. Vessel protection device
CA2750242C (en) 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
JP5684239B2 (ja) 2009-05-04 2015-03-11 インセプト・リミテッド・ライアビリティ・カンパニーＩｎｃｅｐｔ Ｌｌｃ 軌道および穿刺部閉鎖用の生体材料
US9649331B2 (en) * 2009-08-27 2017-05-16 Ara Medical Llc Sprayable polymers as adhesion barriers
US8795727B2 (en) 2009-11-09 2014-08-05 Spotlight Technology Partners Llc Fragmented hydrogels
US9700650B2 (en) 2009-11-09 2017-07-11 Spotlight Technology Partners Llc Polysaccharide based hydrogels
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
EP2624874A4 (de) 2010-10-08 2014-04-02 Univ Texas Haftungsverhindernde sperrmembran mit alginat und hyaluronsäure für biomedizinische anwendungen
JP5978420B2 (ja) * 2011-07-27 2016-08-24 旭化成株式会社 カルボキシルエチルセルロースからなるシート状構造体
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
TWI561535B (en) 2011-10-06 2016-12-11 Bvw Holding Ag Copolymers of hydrophobic and hydrophilic segments that reduce protein adsorption
WO2013086015A1 (en) 2011-12-05 2013-06-13 Incept, Llc Medical organogel processes and compositions
RU2509784C2 (ru) * 2012-04-10 2014-03-20 Общество с ограниченной ответственностью "Линтекс" Способ получения пористых, пленочных материалов на основе карбоксиметилцеллюлозы
US10086110B2 (en) * 2012-10-30 2018-10-02 The Cleveland Clinic Foundation Multipurpose membranes, methods for forming, and applications thereof
KR101468287B1 (ko) * 2013-02-06 2014-12-02 주식회사 제네웰 고분자 조성물 및 이로부터 탄성 창상피복재의 제조방법
WO2015042462A1 (en) 2013-09-19 2015-03-26 Microvention, Inc. Polymer films
US9546236B2 (en) 2013-09-19 2017-01-17 Terumo Corporation Polymer particles
WO2015070094A1 (en) 2013-11-08 2015-05-14 Microvention, Inc. Polymer particles
DK3145548T3 (en) * 2014-05-22 2022-07-04 Univ Copenhagen Aqueous gel composition and its use
WO2016154592A1 (en) 2015-03-26 2016-09-29 Microvention, Inc. Embiolic particles
WO2017121049A1 (en) 2016-01-15 2017-07-20 Findpiano Information Technology (Shanghai) Co., Ltd. Piano system and operating method thereof
RU2629842C1 (ru) * 2016-07-26 2017-09-04 Общество с ограниченной ответственностью "Линтекс" Способ получения противоспаечного пленочного материала на основе карбоксиметилцеллюлозы
RU2634577C1 (ru) * 2016-07-26 2017-10-31 Общество с ограниченной ответственностью "Линтекс" Способ получения противоспаечного пленочного материала на основе производных целлюлозы
RU2629841C1 (ru) * 2016-07-26 2017-09-04 Общество с ограниченной ответственностью "Линтекс" Способ получения противоспаечного пленочного материала на основе карбоксиметилцеллюлозы
CA3038719C (en) 2016-09-28 2020-04-21 Terumo Corporation Polymer particles
US11872711B2 (en) * 2019-05-10 2024-01-16 The Gillette Company Llc Lubricating member for razor cartridges

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3064313A (en) * 1960-06-14 1962-11-20 Hercules Powder Co Ltd Preparation of free acid cellulose ether films
US3328259A (en) * 1964-01-08 1967-06-27 Parachem Corp Dressing for a wound containing a hemostatic agent and method of treating a wound
US3387061A (en) * 1966-05-04 1968-06-04 Union Carbide Corp Chemical reaction product of polycarboxylic acid and a polymeric polyether
US4585858A (en) * 1967-01-03 1986-04-29 Cpc International Inc. Starch-based polyether polyols
US4024073A (en) * 1972-01-08 1977-05-17 Toray Industries, Inc. Hydrogel and production thereof
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4301067A (en) * 1979-06-05 1981-11-17 Kureha Kagaku Kogyo Kabushiki Kaisha Chitin containing poly-ion complex
JPS5844711B2 (ja) * 1979-07-04 1983-10-05 日東電工株式会社 水溶性感圧接着剤組成物
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
US4456596A (en) * 1981-04-13 1984-06-26 Schaefer Rolf Wound healing glycoside compositions
US4768523A (en) * 1981-04-29 1988-09-06 Lifecore Biomedical, Inc. Hydrogel adhesive
US4517295A (en) * 1983-02-18 1985-05-14 Diagnostic, Inc. Hyaluronic acid from bacterial culture
LU85582A1 (fr) * 1983-10-11 1985-06-04 Fidia Spa Fractions d'acide hyaluronique ayant une activite pharmaceutique,procedes pour leur preparation et compositions pharmaceutiques les contenant
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4616644A (en) * 1985-06-14 1986-10-14 Johnson & Johnson Products, Inc. Hemostatic adhesive bandage
IN166447B (de) * 1985-11-27 1990-05-12 Ethicon Inc
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4684558A (en) * 1986-06-30 1987-08-04 Nepera Inc. Adhesive polyethylene oxide hydrogel sheet and its production
US5080893A (en) * 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
US4983585A (en) * 1987-05-04 1991-01-08 Mdr Group, Inc. Viscoelastic fluid for use in surgery and other therapies and method of using same
US5068225A (en) * 1987-05-04 1991-11-26 Mdr Group, Inc. Viscoelastic fluid for use in surgery and other therapies and method of using same
US5156839A (en) * 1987-05-04 1992-10-20 Mdr Group, Inc. Viscoelastic fluid for use in spine and general surgery and other surgery and therapies and method of using same
US4853374A (en) * 1987-06-09 1989-08-01 M.D.R. Group, Inc. Viscoelastic vitreous substitute with UV blocker
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5140016A (en) * 1988-05-31 1992-08-18 University Of Florida Method and composition for preventing surgical adhesions using a dilute solution of polymer
HU203372B (en) * 1989-02-24 1991-07-29 Richter Gedeon Vegyeszet Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient
US5143071A (en) * 1989-03-30 1992-09-01 Nepera, Inc. Non-stringy adhesive hydrophilic gels
US5356883A (en) * 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
US5093319A (en) * 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
GR920100122A (el) * 1991-04-05 1993-03-16 Ethicon Inc Πολυσακχαρίτες οι οποίοι περιέχουν καρβοξύλιο με σταυροειδείς δεσμούς δια την πρόληψιν της προσφύσεως.
US5266326A (en) * 1992-06-30 1993-11-30 Pfizer Hospital Products Group, Inc. In situ modification of alginate
US5681873A (en) * 1993-10-14 1997-10-28 Atrix Laboratories, Inc. Biodegradable polymeric composition
US5374446A (en) * 1993-12-10 1994-12-20 Arco Chemical Technology, L.P. Linked esterified alkoxylated polyols useful as reduced calorie fat substitutes
US5621093A (en) * 1995-06-06 1997-04-15 Anika Research, Inc. Steam-sterilizing solid hyaluronic acid
ES2152579T3 (es) * 1995-12-21 2001-02-01 Dow Chemical Co Composiciones que comprenden polimeros con funcion hidroxi.
JPH10290830A (ja) * 1997-04-18 1998-11-04 Ofutekusu:Kk 眼手術用補助剤
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions

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CA2294200C (en) 2008-10-14
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AU7698598A (en) 1999-01-04
EP1002002A1 (de) 2000-05-24
KR100612975B1 (ko) 2006-08-16
AU754787B2 (en) 2002-11-28
US6133325A (en) 2000-10-17
KR20010013927A (ko) 2001-02-26
DE69838614T2 (de) 2008-08-28
EP1002002B1 (de) 2007-10-24
CA2294200A1 (en) 1998-12-23
EP1002002A4 (de) 2004-03-17
JP2002511897A (ja) 2002-04-16
WO1998058011A1 (en) 1998-12-23
US5906997A (en) 1999-05-25
ATE376567T1 (de) 2007-11-15

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