DE69837894D1 - Implantierbare Verabreichungsvorrichtung mit einer selbstjustierenden Ausgangsöffnung - Google Patents

Implantierbare Verabreichungsvorrichtung mit einer selbstjustierenden Ausgangsöffnung

Info

Publication number
DE69837894D1
DE69837894D1 DE69837894T DE69837894T DE69837894D1 DE 69837894 D1 DE69837894 D1 DE 69837894D1 DE 69837894 T DE69837894 T DE 69837894T DE 69837894 T DE69837894 T DE 69837894T DE 69837894 D1 DE69837894 D1 DE 69837894D1
Authority
DE
Germany
Prior art keywords
self
delivery device
exit port
implantable delivery
aligning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837894T
Other languages
English (en)
Other versions
DE69837894T2 (de
Inventor
Juan C Gumucio
Keith A Dionne
James E Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intarcia Therapeutics Inc
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69837894D1 publication Critical patent/DE69837894D1/de
Publication of DE69837894T2 publication Critical patent/DE69837894T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
DE69837894T 1997-03-24 1998-03-10 Implantierbare Verabreichungsvorrichtung mit einer selbstjustierenden Ausgangsöffnung Expired - Lifetime DE69837894T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3560797P 1997-03-24 1997-03-24
US35607P 1997-03-24

Publications (2)

Publication Number Publication Date
DE69837894D1 true DE69837894D1 (de) 2007-07-19
DE69837894T2 DE69837894T2 (de) 2008-01-31

Family

ID=21883714

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69837894T Expired - Lifetime DE69837894T2 (de) 1997-03-24 1998-03-10 Implantierbare Verabreichungsvorrichtung mit einer selbstjustierenden Ausgangsöffnung
DE69828157T Expired - Lifetime DE69828157T2 (de) 1997-03-24 1998-03-10 Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69828157T Expired - Lifetime DE69828157T2 (de) 1997-03-24 1998-03-10 Implantierbare verabreichungsvorrichtung mit einer selbstjustierenden ausgangsöffnung

Country Status (20)

Country Link
US (2) US5997527A (de)
EP (1) EP0969820B1 (de)
JP (1) JP2002513414A (de)
KR (1) KR100572188B1 (de)
CN (2) CN1139411C (de)
AR (1) AR010407A1 (de)
AT (2) ATE363897T1 (de)
AU (1) AU738417B2 (de)
CA (1) CA2284929C (de)
CO (1) CO5021220A1 (de)
DE (2) DE69837894T2 (de)
ES (1) ES2232940T3 (de)
HK (2) HK1025049A1 (de)
IL (1) IL132041A0 (de)
MY (1) MY123359A (de)
NZ (1) NZ338024A (de)
PT (1) PT969820E (de)
TW (1) TW369419B (de)
WO (1) WO1998042317A2 (de)
ZA (1) ZA981610B (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
EP1140014B1 (de) * 1998-12-31 2003-03-19 Alza Corporation Osmotisches verabreichungsystem mit raumsparenden kolben
US7919109B2 (en) * 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
DK1328256T3 (da) 1999-12-21 2006-02-20 Alza Corp Ventil til osmotiske indretninger
PL356639A1 (en) * 1999-12-27 2004-06-28 Alza Corporation Osmotic beneficial agent delivery system
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
US6454759B2 (en) * 2000-02-28 2002-09-24 The Regents Of The University Of California Microfabricated injectable drug delivery system
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US6796972B1 (en) 2000-07-14 2004-09-28 Edwards Lifesciences Llc Catheter anchoring balloon structure with irrigation
US6464662B1 (en) 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US6561479B1 (en) * 2000-08-23 2003-05-13 Micron Technology, Inc. Small scale actuators and methods for their formation and use
US6605055B1 (en) 2000-09-13 2003-08-12 Cardiofocus, Inc. Balloon catheter with irrigation sheath
AU2007202144B2 (en) * 2000-11-29 2009-04-23 Durect Corporation Devices and methods for controlled delivery from a drug delivery device
JP4248236B2 (ja) * 2000-11-29 2009-04-02 デュレクト コーポレイション 薬物送達装置からの送達を制御するための装置および方法
CA2434156A1 (en) 2000-12-29 2002-07-25 Bausch & Lomb Incorporated Sustained release drug delivery devices
DE60130928T2 (de) * 2001-01-03 2008-07-17 Bausch & Lomb Inc. Vorrichtung zur verzögerten wirkstofffreisetzung mit beschichteten medikamentenkernen
US6756058B2 (en) 2001-01-03 2004-06-29 Bausch & Lomb Incorporated Sustained release drug delivery devices with multiple agents
US6805207B2 (en) * 2001-01-23 2004-10-19 Black & Decker Inc. Housing with functional overmold
US6632217B2 (en) 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
GB2374905B (en) * 2001-04-27 2004-09-15 Reckitt Benckiser Uk Ltd Aerosol delivery system
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
EP1435919B1 (de) * 2001-09-17 2009-09-23 Durect Corporation Vorrichtung und verfahren zur genauen abgabe eines wirkstoffs
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US7074423B2 (en) * 2002-06-17 2006-07-11 Alza Corporation Osmotic delivery system with early zero order push power engine
NZ537628A (en) * 2002-06-26 2005-12-23 Alza Corp Minimally compliant, volume efficient piston for osmotic drug delivery systems
US20060009739A1 (en) * 2002-09-06 2006-01-12 Durect Corporation Implantable flow regulator with failsafe mode and reserve drug supply
US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
BR0317421A (pt) * 2002-12-19 2005-11-08 Alza Corp Géis de fase única não-aquosa estável e formulações destes para liberação a partir de um dispositivo implantável
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
AR043811A1 (es) 2003-03-31 2005-08-17 Alza Corp Vehiculos de fase unica no acuosos y formulaciones que utilizan dichos vehiculos
CL2004000697A1 (es) * 2003-03-31 2005-05-20 Alza Corp Dispositivo de administracion osmotica que comprende: un reservorio, una composicion osmotica, la formulacion de la droga, y una membrana precargada que comprende un material semipermeable y un material liquido de relleno seleccionado de un polietile
NZ542779A (en) * 2003-03-31 2009-02-28 Intarcia Therapeutics Inc Osmotic pump with means for dissipating internal pressure by allowing osmotic material to be ejected from the container above a set internal pressure
US8491571B2 (en) 2003-06-12 2013-07-23 Cordis Corporation Orifice device having multiple channels with varying flow rates for drug delivery
US7211076B2 (en) 2003-06-12 2007-05-01 Cordis Corporation Medical device for fluid delivery having low fluid flow rate
US8109922B2 (en) 2003-06-12 2012-02-07 Cordis Corporation Orifice device having multiple channels and multiple layers for drug delivery
US7108762B2 (en) 2003-06-12 2006-09-19 Cordis Corporation Method for manufacturing an orifice mechanism capable of low fluid flow rates
US7678103B2 (en) 2003-06-12 2010-03-16 Cordis Corporation Orifice device for delivering drugs at low fluid flow rates
US6976983B2 (en) 2003-06-12 2005-12-20 Cordis Corporation Implantable device for delivering drugs using orifice mechanism capable of low fluid flow rates
US7241457B2 (en) 2003-09-30 2007-07-10 Alza Corporation Osmotically driven active agent delivery device providing an ascending release profile
JP2007526792A (ja) * 2003-11-06 2007-09-20 アルザ・コーポレーシヨン 移植可能な浸透ポンプと一緒の使用のためのモジュール型の吸入速度低下器
US20050175701A1 (en) * 2004-02-10 2005-08-11 Alza Corporation Capillary moderator for osmotic delivery system
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US7731715B2 (en) 2004-12-10 2010-06-08 Edwards Lifesciences Corporation Ablative treatment of atrial fibrillation via the coronary sinus
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US20060263433A1 (en) * 2005-02-03 2006-11-23 Ayer Rupal A Suspension formulation of interferon
US8299025B2 (en) 2005-02-03 2012-10-30 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US7959938B2 (en) 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070027105A1 (en) * 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
CN101351148B (zh) * 2005-12-28 2010-09-08 奥林巴斯医疗株式会社 被检体内观察系统
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
KR101200728B1 (ko) 2006-08-09 2012-11-13 인타르시아 세라퓨틱스 인코포레이티드 삼투성 전달 시스템 및 피스톤 조립체
US8617143B2 (en) * 2006-12-07 2013-12-31 The Regents Of The University Of California Therapeutic agent delivery systems and devices
EP2240155B1 (de) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe
US20090259112A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Sensors
US20090259217A1 (en) * 2008-04-09 2009-10-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems associated with delivery of one or more agents to an individual
US8028743B2 (en) * 2008-04-17 2011-10-04 Hewlett-Packard Development Company, L.P. Passive cooling in response to ambient environmental properties
ES2604590T3 (es) * 2008-09-10 2017-03-07 Sandoz Ag Cápsula con elemento de bloqueo soluble
CN106880596A (zh) * 2008-10-15 2017-06-23 精达制药公司 高浓缩药物颗粒、制剂、混悬剂及其应用
HUE035862T2 (en) 2009-09-28 2018-05-28 Intarcia Therapeutics Inc Rapid development and / or completion of substantially steady-state drug delivery
US8038650B2 (en) * 2010-02-22 2011-10-18 Microsert Ltd. Slow release liquid drug delivery device
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US8986337B2 (en) 2012-02-24 2015-03-24 Elwha Llc Devices, systems, and methods to control stomach volume
CN104001261A (zh) * 2013-02-27 2014-08-27 重庆市北碚区精神卫生中心 一种皮下给药装置
JP2016508842A (ja) 2013-03-05 2016-03-24 タリス バイオメディカル エルエルシー 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法
KR102339132B1 (ko) * 2013-03-15 2021-12-13 타리스 바이오메디컬 엘엘씨 약물 전달 장치 및 약물 전달 방법
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
EP3302354B1 (de) 2015-06-03 2023-10-04 i2o Therapeutics, Inc. Systeme zum einsetzen eines implantats
MX2018005689A (es) 2015-11-05 2018-08-01 Massachusetts Gen Hospital Administracion intratecal de secuencias de acido nucleico que codifican abcd1 para el tratamiento de la adrenomieloneuropatia.
BR112018073511A2 (pt) 2016-05-16 2019-03-26 Intarcia Therapeutics, Inc. polipeptídeos seletivos do receptor de glucagon e métodos de uso dos mesmos
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
AU2017345724B2 (en) 2016-10-20 2024-04-18 Peptron, Inc. Methods of delivering a neuroprotective polypeptide to the central nervous system
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
ES2873084T3 (es) * 2017-02-01 2021-11-03 Taris Biomedical Llc Dispositivos para la administración de fármacos in vivo
AU2018231249A1 (en) 2017-03-08 2019-09-26 Intarcia Therapeutics, Inc Apparatus and methods for administration of a nauseogenic compound from a drug delivery device
CA3064423A1 (en) * 2017-05-29 2018-12-06 Bionaut Labs Ltd. Triggering of payload release from miniaturized devices
CN108339189A (zh) * 2018-02-08 2018-07-31 孙玉荣 一种口腔给药治疗装置
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
CN113195524A (zh) 2018-10-11 2021-07-30 因塔西亚治疗公司 人类胰淀素类似物多肽和使用方法
WO2020089016A1 (en) * 2018-10-30 2020-05-07 F. Hoffmann-La Roche Ag Implantation needle and kit
CN110613872A (zh) * 2019-10-31 2019-12-27 厦门大学嘉庚学院 一种防止血液凝固的留置针辅助装置及其工作方法
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CN112370645A (zh) * 2020-11-25 2021-02-19 珠海市人民医院 一种皮肤涂药瓶及使用方法
WO2023181996A1 (ja) * 2022-03-25 2023-09-28 テルモ株式会社 投与装置

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3987790A (en) * 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
GB2048710B (en) * 1979-05-07 1983-03-09 Alza Corp Osmotically driven fluid dispenser
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
US4781714A (en) * 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
AU645527B2 (en) * 1990-01-24 1994-01-20 Alza Corporation Delivery system comprising means for controlling internal pressure
US5122128A (en) * 1990-03-15 1992-06-16 Alza Corporation Orifice insert for a ruminal bolus
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
PT100944B (pt) * 1991-10-10 2000-02-29 Alza Corp Dispositivo para o fornecimento osmotico de farmacos com paredes de materiais hidrofobicos
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5639477A (en) * 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
ES2246004T3 (es) * 1996-02-02 2006-02-01 Alza Corporation Liberacion prolongada de un agente activo usando un sistema implantable.

Also Published As

Publication number Publication date
NZ338024A (en) 2001-06-29
WO1998042317A2 (en) 1998-10-01
CN1251036A (zh) 2000-04-19
AU738417B2 (en) 2001-09-20
CN1504242A (zh) 2004-06-16
CA2284929A1 (en) 1998-10-01
EP0969820A2 (de) 2000-01-12
DE69828157T2 (de) 2005-12-22
IL132041A0 (en) 2001-03-19
WO1998042317A3 (en) 1998-12-30
HK1025049A1 (en) 2000-11-03
HK1067077A1 (en) 2005-04-01
MY123359A (en) 2006-05-31
AR010407A1 (es) 2000-06-07
AU6547298A (en) 1998-10-20
ZA981610B (en) 1999-08-26
PT969820E (pt) 2005-02-28
ATE284679T1 (de) 2005-01-15
DE69837894T2 (de) 2008-01-31
US6217906B1 (en) 2001-04-17
CA2284929C (en) 2006-12-19
EP0969820B1 (de) 2004-12-15
ATE363897T1 (de) 2007-06-15
US5997527A (en) 1999-12-07
KR20010005657A (ko) 2001-01-15
ES2232940T3 (es) 2005-06-01
DE69828157D1 (de) 2005-01-20
KR100572188B1 (ko) 2006-04-18
CN1139411C (zh) 2004-02-25
JP2002513414A (ja) 2002-05-08
TW369419B (en) 1999-09-11
CO5021220A1 (es) 2001-03-27
CN1290590C (zh) 2006-12-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: INTARCIA THERAPEUTICS, INC., HAYWARD, CA, US

8328 Change in the person/name/address of the agent

Representative=s name: HEYER, V., DIPL.-PHYS. DR.RER.NAT., PAT.-ANW., 806