DE69835207D1 - Synthese von oligonukleotiden - Google Patents
Synthese von oligonukleotidenInfo
- Publication number
- DE69835207D1 DE69835207D1 DE69835207T DE69835207T DE69835207D1 DE 69835207 D1 DE69835207 D1 DE 69835207D1 DE 69835207 T DE69835207 T DE 69835207T DE 69835207 T DE69835207 T DE 69835207T DE 69835207 D1 DE69835207 D1 DE 69835207D1
- Authority
- DE
- Germany
- Prior art keywords
- oligonucleotide
- free
- solid support
- oligonucleotides
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9701783A SE9701783D0 (sv) | 1997-05-14 | 1997-05-14 | In situ synthesis of oligonucleotides of inverse orientation |
PCT/SE1998/000893 WO1998051698A1 (en) | 1997-05-14 | 1998-05-14 | Synthesis of oligonucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69835207D1 true DE69835207D1 (de) | 2006-08-24 |
Family
ID=20406926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69835207T Expired - Lifetime DE69835207D1 (de) | 1997-05-14 | 1998-05-14 | Synthese von oligonukleotiden |
Country Status (8)
Country | Link |
---|---|
US (2) | US6313284B1 (de) |
EP (1) | EP0983288B1 (de) |
JP (1) | JP2001525821A (de) |
AT (1) | ATE332911T1 (de) |
CA (1) | CA2289204A1 (de) |
DE (1) | DE69835207D1 (de) |
SE (1) | SE9701783D0 (de) |
WO (1) | WO1998051698A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9701783D0 (sv) * | 1997-05-14 | 1997-05-14 | Marek Kwiatkowski | In situ synthesis of oligonucleotides of inverse orientation |
US6309836B1 (en) | 1999-10-05 | 2001-10-30 | Marek Kwiatkowski | Compounds for protecting hydroxyls and methods for their use |
EP1234058A2 (de) * | 1999-11-26 | 2002-08-28 | Curagen Corporation | Nukleinsäuresondenarrays |
EP1283881A2 (de) * | 2000-05-26 | 2003-02-19 | Noxxon Pharma AG | Immobilisierte nukleinsäuren und verwendungen davon |
US6932943B1 (en) | 2001-01-26 | 2005-08-23 | Third Wave Technologies | Nucleic acid synthesizers |
US7435390B2 (en) * | 2001-01-26 | 2008-10-14 | Third Wave Technologies, Inc. | Nucleic acid synthesizers |
EP1412522A1 (de) | 2001-06-15 | 2004-04-28 | Quiatech AB | Amplifizierbare sonde |
US7345163B2 (en) | 2002-08-28 | 2008-03-18 | Quiatech Ab | Process for separating and deprotecting oligonucleotides |
WO2005113804A1 (en) * | 2004-05-20 | 2005-12-01 | Trillion Genomics Limited | Use of mass labelled probes to detect target nucleic acids using mass spectrometry |
US20060068424A1 (en) * | 2004-08-13 | 2006-03-30 | Fuji Photo Film Co., Ltd. | Biosensor |
EP1788875A4 (de) * | 2004-08-20 | 2010-12-15 | Dharmacon Inc | Neue polynukleotidsynthese durch markierungschemie |
US9249460B2 (en) | 2011-09-09 | 2016-02-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for obtaining a sequence |
US10378051B2 (en) * | 2011-09-29 | 2019-08-13 | Illumina Cambridge Limited | Continuous extension and deblocking in reactions for nucleic acids synthesis and sequencing |
JP2013198425A (ja) * | 2012-03-24 | 2013-10-03 | Kanagawa Univ | オリゴヌクレオチドの製造方法 |
US10533216B2 (en) | 2014-05-23 | 2020-01-14 | Centrillion Technology Holdings Corporation | Oligonucleotide probe inversion process for in situ synthesized probe arrays |
EP3133171B1 (de) * | 2015-08-18 | 2018-10-17 | Centrillion Technology Holdings Corporation | Sondeninversionsverfahren für in-situ-synthetisierte sondenarrays |
US10695735B2 (en) | 2015-08-18 | 2020-06-30 | Centrillion Technology Holdings Corporation | Probe inversion process for in situ synthesized probe arrays |
WO2018102660A1 (en) * | 2016-12-02 | 2018-06-07 | Centrillion Technologies, Inc. | In situ probe inversion process for constructing probe arrays |
EP3768881A4 (de) * | 2018-03-21 | 2021-12-15 | Centrillion Technology Holdings Corporation | Verfahren und system zur herstellung von dna-sequenzierungsarrays |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE113059T1 (de) * | 1987-06-24 | 1994-11-15 | Florey Howard Inst | Nukleosid-derivate. |
SE9003743D0 (sv) | 1990-11-26 | 1990-11-26 | Pharmacia Ab | Method and means for oligonucleotide synthesis |
US5550215A (en) * | 1991-11-22 | 1996-08-27 | Holmes; Christopher P. | Polymer reversal on solid surfaces |
US5462854A (en) * | 1993-04-19 | 1995-10-31 | Beckman Instruments, Inc. | Inverse linkage oligonucleotides for chemical and enzymatic processes |
SE9701783D0 (sv) * | 1997-05-14 | 1997-05-14 | Marek Kwiatkowski | In situ synthesis of oligonucleotides of inverse orientation |
-
1997
- 1997-05-14 SE SE9701783A patent/SE9701783D0/xx unknown
-
1998
- 1998-05-14 WO PCT/SE1998/000893 patent/WO1998051698A1/en active IP Right Grant
- 1998-05-14 EP EP98923266A patent/EP0983288B1/de not_active Expired - Lifetime
- 1998-05-14 AT AT98923266T patent/ATE332911T1/de not_active IP Right Cessation
- 1998-05-14 JP JP54915198A patent/JP2001525821A/ja not_active Abandoned
- 1998-05-14 DE DE69835207T patent/DE69835207D1/de not_active Expired - Lifetime
- 1998-05-14 CA CA002289204A patent/CA2289204A1/en not_active Abandoned
- 1998-05-14 US US09/423,742 patent/US6313284B1/en not_active Expired - Fee Related
-
2001
- 2001-09-12 US US09/952,944 patent/US6790946B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0983288B1 (de) | 2006-07-12 |
WO1998051698A8 (en) | 1999-06-10 |
US6313284B1 (en) | 2001-11-06 |
EP0983288A1 (de) | 2000-03-08 |
WO1998051698A1 (en) | 1998-11-19 |
ATE332911T1 (de) | 2006-08-15 |
JP2001525821A (ja) | 2001-12-11 |
SE9701783D0 (sv) | 1997-05-14 |
US6790946B2 (en) | 2004-09-14 |
US20020051994A1 (en) | 2002-05-02 |
CA2289204A1 (en) | 1998-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |