DE69831522T2 - In-situ Zellextraktion und Assay-Verfahren - Google Patents

In-situ Zellextraktion und Assay-Verfahren Download PDF

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Publication number
DE69831522T2
DE69831522T2 DE69831522T DE69831522T DE69831522T2 DE 69831522 T2 DE69831522 T2 DE 69831522T2 DE 69831522 T DE69831522 T DE 69831522T DE 69831522 T DE69831522 T DE 69831522T DE 69831522 T2 DE69831522 T2 DE 69831522T2
Authority
DE
Germany
Prior art keywords
cell extraction
assay procedures
situ cell
situ
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831522T
Other languages
English (en)
Other versions
DE69831522D1 (de
Inventor
Jeffrey Kenneth Dr Horton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare UK Ltd
Original Assignee
Amersham Biosciences UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9715704.4A external-priority patent/GB9715704D0/en
Application filed by Amersham Biosciences UK Ltd filed Critical Amersham Biosciences UK Ltd
Publication of DE69831522D1 publication Critical patent/DE69831522D1/de
Application granted granted Critical
Publication of DE69831522T2 publication Critical patent/DE69831522T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/88—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving prostaglandins or their receptors
DE69831522T 1997-03-03 1998-02-18 In-situ Zellextraktion und Assay-Verfahren Expired - Lifetime DE69831522T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97301398 1997-03-03
GBGB9715704.4A GB9715704D0 (en) 1997-07-24 1997-07-24 In-situ cell extraction and assay method

Publications (2)

Publication Number Publication Date
DE69831522D1 DE69831522D1 (de) 2005-10-20
DE69831522T2 true DE69831522T2 (de) 2006-06-14

Family

ID=26147318

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831522T Expired - Lifetime DE69831522T2 (de) 1997-03-03 1998-02-18 In-situ Zellextraktion und Assay-Verfahren

Country Status (6)

Country Link
US (1) US6900019B1 (de)
EP (1) EP0863402B1 (de)
JP (1) JP4012301B2 (de)
CA (1) CA2230423C (de)
DE (1) DE69831522T2 (de)
ES (1) ES2246522T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69935850T2 (de) * 1998-02-16 2008-01-10 Ge Healthcare Uk Ltd., Little Chalfont Verfahren zur messung der gesamkonzentration eines analytes
WO2004042003A2 (en) * 2002-11-01 2004-05-21 Promega Corporation Cell lysis compositions, methods of use, apparatus, and kit
CA2524393A1 (en) * 2003-05-02 2004-11-18 Sigma-Aldrich Co. Solid phase cell lysis and capture platform
BRPI0706505A2 (pt) 2006-01-10 2011-03-29 Colgate Palmolive Co métodos de distinção entre espécies de bactérias orais, de determinação do efeito antiinflamatório de um agente, de prevenção da modulação de um receptor tipo toll em uma célula da cavidade oral de um mamìfero, e, de redução ou prevenção da inflamação de um tecido oral
GB0800938D0 (en) * 2008-01-18 2008-02-27 Ge Healthcare Uk Ltd Multiplex cell signalling assay
US9678079B2 (en) * 2012-10-08 2017-06-13 General Electric Company Microfluidic LAL-reactive substances testing method and apparatus
CN107208136A (zh) * 2014-12-18 2017-09-26 通用电气医疗集团英国有限公司 通过与免疫测定法偶联的核酸扩增的固体支持物上的分析物检测

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1604249A (en) 1977-05-31 1981-12-02 Kolehmainen S Selective measurement of somatic and microbial cells
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US5185432A (en) 1986-02-26 1993-02-09 Oncogen Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas
US4956274A (en) 1987-04-06 1990-09-11 Microgenics Corporation Reagent stabilization in enzyme-donor and acceptor assay
EP0301847A1 (de) 1987-07-29 1989-02-01 Microgenics Corporation Reinigung unter Verwendung von Cyclodextrin
GB8722252D0 (en) * 1987-09-22 1987-10-28 Brewing Res Found Atp extraction
US5268299A (en) 1988-04-14 1993-12-07 Eastman Kodak Company Diluent composition useful in the detection of antibodies in assays
US5032503A (en) * 1988-06-22 1991-07-16 Microgenics Corporation Liquid single reagent for air enzyme complementation assay
SE8803602D0 (sv) 1988-10-11 1988-10-11 Wallac Oy A sample plate with a plurality of sample wells or vials intended for radiolabeled binding assays
US5705345A (en) * 1991-01-10 1998-01-06 Amersham International Plc Methods and kits for preparing nucleic acids using cyclodextrin
GB9100551D0 (en) * 1991-01-10 1991-02-20 Amersham Int Plc Method and reagent for eliminating analytical interference in enzymatic analysis from substances used for extraction of intracellular metabolites
DE650396T1 (de) 1993-05-17 1995-11-30 Amersham Int Plc Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse.
WO1997023782A1 (en) * 1995-12-22 1997-07-03 Abbott Laboratories Fluorescence polarization immunoassay diagnostic method
US5739001A (en) 1996-10-29 1998-04-14 E. I. Du Pont De Nemours And Company Solid phase cell-based assay

Also Published As

Publication number Publication date
JPH10253630A (ja) 1998-09-25
EP0863402B1 (de) 2005-09-14
EP0863402A2 (de) 1998-09-09
DE69831522D1 (de) 2005-10-20
CA2230423C (en) 2007-02-06
EP0863402A3 (de) 1999-07-21
CA2230423A1 (en) 1998-09-03
JP4012301B2 (ja) 2007-11-21
ES2246522T3 (es) 2006-02-16
US6900019B1 (en) 2005-05-31

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: HAMMONDS RECHTSANWAELTE PATENTANWAELTE, 80539 MUENCHEN

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GE HEALTHCARE UK LTD., LITTLE CHALFONT, BUCKINGHAM

8328 Change in the person/name/address of the agent

Representative=s name: HAMMONDS LLP, LONDON, GB

R082 Change of representative

Ref document number: 863402

Country of ref document: EP

Representative=s name: J D REYNOLDS & CO., GB