DE69823206D1 - Verfahren zur herstellung einer bio-informatik-datenbank - Google Patents

Verfahren zur herstellung einer bio-informatik-datenbank

Info

Publication number
DE69823206D1
DE69823206D1 DE69823206T DE69823206T DE69823206D1 DE 69823206 D1 DE69823206 D1 DE 69823206D1 DE 69823206 T DE69823206 T DE 69823206T DE 69823206 T DE69823206 T DE 69823206T DE 69823206 D1 DE69823206 D1 DE 69823206D1
Authority
DE
Germany
Prior art keywords
chips
database
bio
producing
model
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69823206T
Other languages
English (en)
Other versions
DE69823206T2 (de
Inventor
David J Balaban
Arun Aggarwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Application granted granted Critical
Publication of DE69823206D1 publication Critical patent/DE69823206D1/de
Publication of DE69823206T2 publication Critical patent/DE69823206T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M1/00—Substation equipment, e.g. for use by subscribers
    • H04M1/006—Call diverting means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/30—Microarray design
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M1/00—Substation equipment, e.g. for use by subscribers
    • H04M1/72—Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724—User interfaces specially adapted for cordless or mobile telephones
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M2207/00—Type of exchange or network, i.e. telephonic medium, in which the telephonic communication takes place
    • H04M2207/20—Type of exchange or network, i.e. telephonic medium, in which the telephonic communication takes place hybrid systems
    • H04M2207/206—Type of exchange or network, i.e. telephonic medium, in which the telephonic communication takes place hybrid systems composed of PSTN and wireless network
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M3/00—Automatic or semi-automatic exchanges
    • H04M3/42—Systems providing special services or facilities to subscribers
    • H04M3/46—Arrangements for calling a number of substations in a predetermined sequence until an answer is obtained
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M3/00—Automatic or semi-automatic exchanges
    • H04M3/42—Systems providing special services or facilities to subscribers
    • H04M3/54—Arrangements for diverting calls for one subscriber to another predetermined subscriber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/92—Computer assisted medical diagnostics
    • Y10S128/922—Computer assisted medical diagnostics including image analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/912—Applications of a database
    • Y10S707/923—Intellectual property
    • Y10S707/924—Patent procedure
    • Y10S707/925—Drafting an application
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/953—Organization of data
    • Y10S707/955—Object-oriented
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/99931—Database or file accessing
    • Y10S707/99933—Query processing, i.e. searching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/99931—Database or file accessing
    • Y10S707/99933—Query processing, i.e. searching
    • Y10S707/99934—Query formulation, input preparation, or translation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/99941—Database schema or data structure
    • Y10S707/99944—Object-oriented database structure
    • Y10S707/99945—Object-oriented database structure processing
DE69823206T 1997-07-25 1998-07-24 Verfahren zur herstellung einer bio-informatik-datenbank Expired - Lifetime DE69823206T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US5384297P 1997-07-25 1997-07-25
US53842P 1997-07-25
US6919897P 1997-12-11 1997-12-11
US6943697P 1997-12-11 1997-12-11
US69198P 1997-12-11
US69436P 1997-12-11
PCT/US1998/015469 WO1999005591A2 (en) 1997-07-25 1998-07-24 Method and apparatus for providing a bioinformatics database

Publications (2)

Publication Number Publication Date
DE69823206D1 true DE69823206D1 (de) 2004-05-19
DE69823206T2 DE69823206T2 (de) 2004-08-19

Family

ID=27368502

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69823206T Expired - Lifetime DE69823206T2 (de) 1997-07-25 1998-07-24 Verfahren zur herstellung einer bio-informatik-datenbank

Country Status (6)

Country Link
US (10) US6484183B1 (de)
EP (4) EP1009861A4 (de)
JP (6) JP3776728B2 (de)
AT (1) ATE264523T1 (de)
DE (1) DE69823206T2 (de)
WO (4) WO1999005324A1 (de)

Families Citing this family (323)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US5989835A (en) 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
WO1999005324A1 (en) * 1997-07-25 1999-02-04 Affymetrix, Inc. System for providing a polymorphism database
US7068830B2 (en) * 1997-07-25 2006-06-27 Affymetrix, Inc. Method and system for providing a probe array chip design database
US6826296B2 (en) * 1997-07-25 2004-11-30 Affymetrix, Inc. Method and system for providing a probe array chip design database
US6420108B2 (en) * 1998-02-09 2002-07-16 Affymetrix, Inc. Computer-aided display for comparative gene expression
US6990221B2 (en) * 1998-02-07 2006-01-24 Biodiscovery, Inc. Automated DNA array image segmentation and analysis
US6349144B1 (en) * 1998-02-07 2002-02-19 Biodiscovery, Inc. Automated DNA array segmentation and analysis
WO1999049403A1 (en) * 1998-03-26 1999-09-30 Incyte Pharmaceuticals, Inc. System and methods for analyzing biomolecular sequences
US6324479B1 (en) * 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6606622B1 (en) * 1998-07-13 2003-08-12 James M. Sorace Software method for the conversion, storage and querying of the data of cellular biological assays on the basis of experimental design
US6185561B1 (en) * 1998-09-17 2001-02-06 Affymetrix, Inc. Method and apparatus for providing and expression data mining database
US20040199544A1 (en) * 2000-11-02 2004-10-07 Affymetrix, Inc. Method and apparatus for providing an expression data mining database
JP2002530748A (ja) 1998-11-13 2002-09-17 セロミックス インコーポレイテッド 実験データを効率的に収集して記憶するための方法及びシステム
US6453241B1 (en) * 1998-12-23 2002-09-17 Rosetta Inpharmatics, Inc. Method and system for analyzing biological response signal data
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US6245511B1 (en) * 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
US6507788B1 (en) * 1999-02-25 2003-01-14 Société de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.) Rational selection of putative peptides from identified nucleotide, or peptide sequences, of unknown function
US6215894B1 (en) * 1999-02-26 2001-04-10 General Scanning, Incorporated Automatic imaging and analysis of microarray biochips
JP2000258368A (ja) * 1999-03-12 2000-09-22 Jeol Ltd サウンドモニタ機能を備えたｘ線マイクロアナライザ
DE60026190T2 (de) * 1999-03-30 2006-08-31 Fuji Photo Film Co., Ltd., Minami-Ashigara Verfahren und Vorrichtung zur selektiven Anzeige von Ergebnissen und übereinstimmenden Bildern
AU4238500A (en) * 1999-04-13 2000-11-14 Richard J. Gagnon Method of obtaining an electronically-stored financial document
US6876760B1 (en) 2000-12-04 2005-04-05 Cytokinetics, Inc. Classifying cells based on information contained in cell images
US20030228565A1 (en) * 2000-04-26 2003-12-11 Cytokinetics, Inc. Method and apparatus for predictive cellular bioinformatics
US6743576B1 (en) 1999-05-14 2004-06-01 Cytokinetics, Inc. Database system for predictive cellular bioinformatics
US6651008B1 (en) 1999-05-14 2003-11-18 Cytokinetics, Inc. Database system including computer code for predictive cellular bioinformatics
US7151847B2 (en) 2001-02-20 2006-12-19 Cytokinetics, Inc. Image analysis of the golgi complex
US6334099B1 (en) 1999-05-25 2001-12-25 Digital Gene Technologies, Inc. Methods for normalization of experimental data
JP3469504B2 (ja) * 1999-06-01 2003-11-25 日立ソフトウエアエンジニアリング株式会社 マイクロアレイチップ及びそのインデックス方法
CA2375220A1 (en) * 1999-06-11 2000-12-21 Narayan Baidya Gene specific arrays and the use thereof
US6716579B1 (en) 1999-06-11 2004-04-06 Narayan Baidya Gene specific arrays, preparation and use
US7058517B1 (en) 1999-06-25 2006-06-06 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US6931396B1 (en) 1999-06-29 2005-08-16 Gene Logic Inc. Biological data processing
US6631211B1 (en) * 1999-07-08 2003-10-07 Perkinelmer Las, Inc. Interactive system for analyzing scatter plots
WO2001013105A1 (en) * 1999-07-30 2001-02-22 Agy Therapeutics, Inc. Techniques for facilitating identification of candidate genes
NZ518022A (en) * 1999-08-27 2004-01-30 Iris Biotechnologies Inc Analysis and diagnosis by intelligent processing of remotely generated genetic hybridization profiles
US7062076B1 (en) 1999-08-27 2006-06-13 Iris Biotechnologies, Inc. Artificial intelligence system for genetic analysis
EP1212599A2 (de) 1999-08-30 2002-06-12 Illumina, Inc. Verfahren zur verbesserung des signals einer sensorarray
US7099502B2 (en) * 1999-10-12 2006-08-29 Biodiscovery, Inc. System and method for automatically processing microarrays
KR20020064298A (ko) 1999-10-13 2002-08-07 시쿼넘, 인코포레이티드 다형성 유전 마커를 동정하기 위한 데이타베이스 및 이의제조 방법
WO2001031333A1 (en) * 1999-10-26 2001-05-03 Genometrix Genomics Incorporated Process for requesting biological experiments and for the delivery of experimental information
ATE391789T1 (de) 1999-12-10 2008-04-15 Invitrogen Corp Verwendung einer vielzahl von rekombinationsstellen mit einzigartiger spezifität beim rekombinatorischen klonen
AU2001229744A1 (en) 2000-01-25 2001-08-07 Cellomics, Inc. Method and system for automated inference of physico-chemical interaction knowl edge
WO2001056216A2 (en) * 2000-01-25 2001-08-02 Affymetrix, Inc. Method, system and computer software for providing a genomic web portal
US20030097222A1 (en) * 2000-01-25 2003-05-22 Craford David M. Method, system, and computer software for providing a genomic web portal
US8076063B2 (en) * 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) * 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US20050214825A1 (en) * 2000-02-07 2005-09-29 John Stuelpnagel Multiplex sample analysis on universal arrays
US6770441B2 (en) * 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
NZ521626A (en) 2000-03-29 2005-09-30 Cambia Methods for genotyping by hybridization analysis
DE10015816A1 (de) * 2000-03-30 2001-10-18 Infineon Technologies Ag Biosensorchip
AU2001251034A1 (en) * 2000-03-31 2001-10-15 Gene Logic, Inc Gene expression profiles in esophageal tissue
US20030040870A1 (en) * 2000-04-18 2003-02-27 Brooke Anderson Automated system and process for custom-designed biological array design and analysis
US20030171876A1 (en) * 2002-03-05 2003-09-11 Victor Markowitz System and method for managing gene expression data
US7020561B1 (en) 2000-05-23 2006-03-28 Gene Logic, Inc. Methods and systems for efficient comparison, identification, processing, and importing of gene expression data
US6741986B2 (en) * 2000-12-08 2004-05-25 Ingenuity Systems, Inc. Method and system for performing information extraction and quality control for a knowledgebase
US7577683B2 (en) 2000-06-08 2009-08-18 Ingenuity Systems, Inc. Methods for the construction and maintenance of a knowledge representation system
US6772160B2 (en) * 2000-06-08 2004-08-03 Ingenuity Systems, Inc. Techniques for facilitating information acquisition and storage
US6931326B1 (en) 2000-06-26 2005-08-16 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US20020152196A1 (en) * 2000-07-07 2002-10-17 Westbrook Carol A. cDNA database and biochip for analysis of hematopoietic tissue
JP3517644B2 (ja) * 2000-07-13 2004-04-12 孝 五條堀 生命体の発現現象表示方法およびシステム並びにプログラム
US20020059326A1 (en) * 2000-07-25 2002-05-16 Derek Bernhart System, method, and computer program product for management of biological experiment information
NL1016034C2 (nl) 2000-08-03 2002-02-08 Tno Werkwijze en systeem voor het identificeren en kwantificeren van chemische componenten van een te onderzoeken mengsel van materialen.
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
AU2001290545A1 (en) * 2000-08-22 2002-03-04 Varro Technologies, Inc. Method and system for sharing biological information
US7062092B2 (en) 2000-08-22 2006-06-13 Affymetrix, Inc. System, method, and computer software product for gain adjustment in biological microarray scanner
AU3511802A (en) 2000-08-22 2002-05-06 Affymetrix, Inc. System method, and computer software product for controlling biological microarray scanner
GB0021286D0 (en) * 2000-08-30 2000-10-18 Gemini Genomics Ab Identification of drug metabolic capacity
US6539102B1 (en) * 2000-09-01 2003-03-25 Large Scale Proteomics Reference database
US6813615B1 (en) 2000-09-06 2004-11-02 Cellomics, Inc. Method and system for interpreting and validating experimental data with automated reasoning
US20020040434A1 (en) * 2000-09-12 2002-04-04 Keith Elliston Techniques for providing and obtaining research and development information technology on remote computing resources
JP2004512514A (ja) * 2000-10-23 2004-04-22 ダイアチップ・リミテッド 再スポット機能を有する高精度知能型バイオチップアレイヤー
US7117095B2 (en) * 2000-11-21 2006-10-03 Affymetrix, Inc. Methods for selecting nucleic acid probes
US8255791B2 (en) 2000-11-29 2012-08-28 Dov Koren Collaborative, flexible, interactive real-time displays
US7218764B2 (en) 2000-12-04 2007-05-15 Cytokinetics, Inc. Ploidy classification method
US6706867B1 (en) * 2000-12-19 2004-03-16 The United States Of America As Represented By The Department Of Health And Human Services DNA array sequence selection
US20020143768A1 (en) * 2000-12-21 2002-10-03 Berno Anthony Berno Probe array data storage and retrieval
AU2002237879A1 (en) * 2001-01-23 2002-08-06 Gene Logic, Inc. A method and system for predicting the biological activity, including toxicology and toxicity, of substances
US20020183936A1 (en) * 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
US20070015148A1 (en) * 2001-01-25 2007-01-18 Orr Michael S Gene expression profiles in breast tissue
US20030017455A1 (en) * 2001-01-29 2003-01-23 Webb Peter G. Chemical array fabrication with identity map
US6949638B2 (en) * 2001-01-29 2005-09-27 Affymetrix, Inc. Photolithographic method and system for efficient mask usage in manufacturing DNA arrays
US7315784B2 (en) * 2001-02-15 2008-01-01 Siemens Aktiengesellschaft Network for evaluating data obtained in a biochip measurement device
US7016787B2 (en) 2001-02-20 2006-03-21 Cytokinetics, Inc. Characterizing biological stimuli by response curves
US6956961B2 (en) 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
JP3867046B2 (ja) * 2001-02-23 2007-01-10 株式会社日立製作所 分析システム
US7110885B2 (en) 2001-03-08 2006-09-19 Dnaprint Genomics, Inc. Efficient methods and apparatus for high-throughput processing of gene sequence data
US20020168651A1 (en) * 2001-03-12 2002-11-14 Affymetrix, Inc. Method and computer software product for determining orientation of sequence clusters
US6804679B2 (en) 2001-03-12 2004-10-12 Affymetrix, Inc. System, method, and user interfaces for managing genomic data
JP2002269114A (ja) * 2001-03-14 2002-09-20 Kousaku Ookubo 知識データベース及び知識データベースの構築方法
WO2002073504A1 (en) * 2001-03-14 2002-09-19 Gene Logic, Inc. A system and method for retrieving and using gene expression data from multiple sources
US20040033502A1 (en) * 2001-03-28 2004-02-19 Amanda Williams Gene expression profiles in esophageal tissue
JP2002297617A (ja) * 2001-03-29 2002-10-11 Hitachi Software Eng Co Ltd 生体高分子とプローブの相関関係表示方法
US7251568B2 (en) 2001-04-18 2007-07-31 Wyeth Methods and compositions for regulating bone and cartilage formation
WO2002085285A2 (en) * 2001-04-18 2002-10-31 Wyeth Methods and reagents for regulating bone and cartilage formation
US7155453B2 (en) * 2002-05-22 2006-12-26 Agilent Technologies, Inc. Biotechnology information naming system
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
CA2447357A1 (en) * 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
US20030009294A1 (en) * 2001-06-07 2003-01-09 Jill Cheng Integrated system for gene expression analysis
WO2002103030A2 (en) * 2001-06-14 2002-12-27 Rigel Pharmaceuticals, Inc. Multidimensional biodata integration and relationship inference
WO2003001335A2 (en) * 2001-06-22 2003-01-03 Gene Logic, Inc. Platform for management and mining of genomic data
KR100794698B1 (ko) * 2001-06-28 2008-01-14 (주)바이오니아 생화학 물질 미세 배열 칩의 품질 검사 방법
EP1417629B1 (de) * 2001-07-06 2008-02-20 Lipomics Technologies, Inc. Erzeugen, betrachten, interpretieren und verwenden einer quantitativen datenbank von metaboliten
US7447594B2 (en) * 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
WO2003068908A2 (en) * 2001-07-10 2003-08-21 Gene Logic, Inc. Cardiotoxin molecular toxicology modeling
WO2003027673A1 (fr) * 2001-07-31 2003-04-03 Olympus Corporation Appareil d'inspection genique et procede d'extraction d'acide nucleique cible faisant appel a cet appareil
US7251642B1 (en) 2001-08-06 2007-07-31 Gene Logic Inc. Analysis engine and work space manager for use with gene expression data
JP3977038B2 (ja) * 2001-08-27 2007-09-19 株式会社半導体エネルギー研究所 レーザ照射装置およびレーザ照射方法
US20030096248A1 (en) * 2001-09-04 2003-05-22 Vitivity, Inc. Diagnosis and treatment of vascular disease
CA2459508A1 (en) * 2001-09-24 2003-04-03 Lipomics Technologies, Inc. Methods of using quantitative lipid metabolome data
JP2003099624A (ja) * 2001-09-25 2003-04-04 Toyo Kohan Co Ltd Ｄｎａ提供システム
US20030087289A1 (en) * 2001-10-12 2003-05-08 Harry Zuzan Image analysis of high-density synthetic DNA microarrays
WO2003033128A2 (en) * 2001-10-12 2003-04-24 Duke University Methods for image analysis of high-density synthetic dna microarrays
US20060141493A1 (en) * 2001-11-09 2006-06-29 Duke University Office Of Science And Technology Atherosclerotic phenotype determinative genes and methods for using the same
JP2005512170A (ja) * 2001-11-12 2005-04-28 ネットワーク リサーチ ラブ リミテッド 不正使用に対する情報保護の方法および装置
KR100474840B1 (ko) * 2001-11-15 2005-03-08 삼성전자주식회사 디렉토리를 이용한 유전자 분석용 마이크로어레이 탐침설계 방법 및 시스템
CN1927466A (zh) * 2001-12-19 2007-03-14 阿菲梅特里克斯公司 阵列板和阵列板的构建方法
US9418204B2 (en) * 2002-01-28 2016-08-16 Samsung Electronics Co., Ltd Bioinformatics system architecture with data and process integration
US7225183B2 (en) * 2002-01-28 2007-05-29 Ipxl, Inc. Ontology-based information management system and method
US20030177143A1 (en) * 2002-01-28 2003-09-18 Steve Gardner Modular bioinformatics platform
US8793073B2 (en) 2002-02-04 2014-07-29 Ingenuity Systems, Inc. Drug discovery methods
WO2003067504A2 (en) 2002-02-04 2003-08-14 Ingenuity Systems, Inc. Drug discovery methods
US20030162183A1 (en) * 2002-02-27 2003-08-28 Robert Kincaid Array design system and method
JP2006506945A (ja) * 2002-03-28 2006-03-02 メディカル・カレッジ・オブ・オハイオ 遺伝子発現プロフィールを使用する非小細胞肺癌の診断および処置のための方法および組成物
WO2003091391A2 (en) * 2002-04-23 2003-11-06 Duke University Atherosclerotic phenotype determinative genes and methods for using the same
AU2003245269A1 (en) * 2002-05-03 2003-11-17 Vialogy Corporation System and method for characterizing microarray output data
US20030220844A1 (en) * 2002-05-24 2003-11-27 Marnellos Georgios E. Method and system for purchasing genetic data
US6763308B2 (en) 2002-05-28 2004-07-13 Sas Institute Inc. Statistical outlier detection for gene expression microarray data
US20030229848A1 (en) * 2002-06-05 2003-12-11 Udo Arend Table filtering in a computer user interface
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
US9898578B2 (en) * 2003-04-04 2018-02-20 Agilent Technologies, Inc. Visualizing expression data on chromosomal graphic schemes
US20050216459A1 (en) * 2002-08-08 2005-09-29 Aditya Vailaya Methods and systems, for ontological integration of disparate biological data
US20050112689A1 (en) * 2003-04-04 2005-05-26 Robert Kincaid Systems and methods for statistically analyzing apparent CGH data anomalies and plotting same
US7941542B2 (en) * 2002-09-06 2011-05-10 Oracle International Corporation Methods and apparatus for maintaining application execution over an intermittent network connection
US7512496B2 (en) * 2002-09-25 2009-03-31 Soheil Shams Apparatus, method, and computer program product for determining confidence measures and combined confidence measures for assessing the quality of microarrays
DE10393406T5 (de) 2002-09-30 2005-12-22 Nimblegen Systems, Inc., Madison Parallele Beladung von Arrays
US20040101894A1 (en) * 2002-10-01 2004-05-27 Thomas Albert Microarrays having multiple oligonucleotides in single array features
US20040259105A1 (en) * 2002-10-03 2004-12-23 Jian-Bing Fan Multiplex nucleic acid analysis using archived or fixed samples
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
EP1562570A4 (de) * 2002-11-06 2007-09-05 Sinai School Medicine Behandlung von amyotropher lateralsklerose mit nimesulid
EP2112229A3 (de) 2002-11-25 2009-12-02 Sequenom, Inc. Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
AU2003293132A1 (en) * 2002-11-27 2004-06-23 Sra International, Inc. Integration of gene expression data and non-gene data
JP2004191160A (ja) * 2002-12-11 2004-07-08 Yokogawa Electric Corp バイオチップの測定方法および測定装置
KR100506089B1 (ko) * 2003-02-05 2005-08-05 삼성전자주식회사 이형 유전정보를 이용한 프로브 어레이 설계 시스템 및 방법
US7750908B2 (en) * 2003-04-04 2010-07-06 Agilent Technologies, Inc. Focus plus context viewing and manipulation of large collections of graphs
US7825929B2 (en) * 2003-04-04 2010-11-02 Agilent Technologies, Inc. Systems, tools and methods for focus and context viewing of large collections of graphs
US7897744B2 (en) * 2003-04-28 2011-03-01 The Public Health Agency Of Canada SARS virus nucleotide and amino acid sequences and uses thereof
US20040249791A1 (en) * 2003-06-03 2004-12-09 Waters Michael D. Method and system for developing and querying a sequence driven contextual knowledge base
WO2005000098A2 (en) 2003-06-10 2005-01-06 The Trustees Of Boston University Detection methods for disorders of the lung
WO2005003301A2 (en) * 2003-06-17 2005-01-13 Signal Pharmaceuticals, Inc. Methods, compositions, and kits for predicting the effect of compounds on hot flash symptoms
US7235353B2 (en) 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US20050014217A1 (en) 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
EP1646926A2 (de) 2003-07-18 2006-04-19 Cytokinetics, Inc. Charakterisierung biologischer stimuli durch ansprechkurven
US7353116B2 (en) * 2003-07-31 2008-04-01 Agilent Technologies, Inc. Chemical array with test dependent signal reading or processing
US20050026306A1 (en) * 2003-07-31 2005-02-03 Robert Kincaid Method and system for generating virtual-microarrays
US20050026154A1 (en) * 2003-07-31 2005-02-03 Laurakay Bruhn Masking chemical arrays
US7475087B1 (en) 2003-08-29 2009-01-06 The United States Of America As Represented By The Secretary Of Agriculture Computer display tool for visualizing relationships between and among data
US20050049796A1 (en) * 2003-09-03 2005-03-03 Webb Peter G. Methods for encoding non-biological information on microarrays
US20050048506A1 (en) * 2003-09-03 2005-03-03 Fredrick Joseph P. Methods for encoding non-biological information on microarrays
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
EP1697534B1 (de) 2003-12-01 2010-06-02 Life Technologies Corporation Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon
EP1564306B1 (de) 2004-02-17 2013-08-07 Affymetrix, Inc. Verfahren zur Fragmentierung und Markierung von DNS
US7660709B2 (en) * 2004-03-18 2010-02-09 Van Andel Research Institute Bioinformatics research and analysis system and methods associated therewith
US9249456B2 (en) 2004-03-26 2016-02-02 Agena Bioscience, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
KR100632973B1 (ko) * 2004-04-29 2006-10-12 주식회사 메딘텔 순환 짝짓기 시스템 및 순환 짝짓기 방법
US20060003335A1 (en) * 2004-06-30 2006-01-05 Crispino John D Methods for diagnosing acute megakaryoblastic leukemia
US7323318B2 (en) 2004-07-15 2008-01-29 Cytokinetics, Inc. Assay for distinguishing live and dead cells
WO2006022628A1 (en) * 2004-07-22 2006-03-02 Sequenom, Inc. Methods for identifying risk of type ii diabetes and treatments thereof
BRPI0513826A2 (pt) * 2004-07-26 2010-06-22 Dow Global Technologies Inc processo para expressão de proteìna melhorada através de engenharia de cepa
US8484000B2 (en) * 2004-09-02 2013-07-09 Vialogy Llc Detecting events of interest using quantum resonance interferometry
US20060073506A1 (en) 2004-09-17 2006-04-06 Affymetrix, Inc. Methods for identifying biological samples
US20060073511A1 (en) 2004-10-05 2006-04-06 Affymetrix, Inc. Methods for amplifying and analyzing nucleic acids
US20060083609A1 (en) * 2004-10-14 2006-04-20 Augspurger Murray D Fluid cooled marine turbine housing
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
CA2524964A1 (en) 2004-10-29 2006-04-29 Affymetrix, Inc. Automated method of manufacturing polymer arrays
WO2006088445A2 (en) * 2005-02-11 2006-08-24 Southern Illinois University Metabolic primers for the detection of (per)chlorate-reducing bacteria and methods of use thereof
US20060211004A1 (en) 2005-02-15 2006-09-21 Ilsley Diane D Methods and compositions for determining non-specific cytotoxicity of a transfection agent
CA2601922C (en) * 2005-02-18 2020-11-24 Monogram Biosciences, Inc. Methods and compositions for determining anti-hiv drug susceptibility and replication capacity of hiv
US20090203547A1 (en) * 2005-02-18 2009-08-13 Albert Banes Gene and Cognate Protein Profiles and Methods to Determine Connective Tissue Markers in Normal and Pathologic Conditions
WO2006089045A2 (en) 2005-02-18 2006-08-24 Monogram Biosciences, Inc. Methods and compositions for determining hypersusceptibility of hiv-1 to non-nucleoside reverse transcriptase inhibitors
US20070118295A1 (en) * 2005-03-02 2007-05-24 Al-Murrani Samer Waleed Khedhe Methods and Systems for Designing Animal Food Compositions
WO2007086890A2 (en) * 2005-03-10 2007-08-02 Genemark Inc. Method, apparatus, and system for authentication using labels containing nucleotide seouences
EP2604703B1 (de) 2005-03-14 2017-02-01 The Board of Trustees of the Leland Stanford Junior University Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate
US20100035244A1 (en) 2005-04-14 2010-02-11 The Trustees Of Boston University Diagnostic for lung disorders using class prediction
WO2006116455A2 (en) 2005-04-26 2006-11-02 Applera Corporation System for genetic surveillance and analysis
WO2006130477A2 (en) 2005-05-27 2006-12-07 Monogram Biosciences, Inc. Methods and compositions for determining resistance of hiv-1 to protease inhibitors
US9506121B2 (en) 2005-06-06 2016-11-29 Monogram Biosciences, Inc. Methods for determining resistance or susceptibility to HIV entry inhibitors
WO2006133267A2 (en) 2005-06-06 2006-12-14 Monogram Biosciences, Inc. Methods and compositions for determining altered susceptibility of hiv-1 to anti-hiv drugs
US8159959B2 (en) * 2005-11-07 2012-04-17 Vudu, Inc. Graphic user interface for playing video data
US7634363B2 (en) 2005-12-07 2009-12-15 Affymetrix, Inc. Methods for high throughput genotyping
US20090215055A1 (en) * 2005-12-13 2009-08-27 Erasmus University Medical Center Rotterdam Genetic Brain Tumor Markers
US7646450B2 (en) * 2005-12-29 2010-01-12 Lg Display Co., Ltd. Light emitting diode array, method of manufacturing the same, backlight assembly having the same, and LCD having the same
US20070198729A1 (en) * 2006-02-07 2007-08-23 Yechuri Sitaramarao S SQL network gadget
US20090061454A1 (en) 2006-03-09 2009-03-05 Brody Jerome S Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
AU2007268369A1 (en) * 2006-05-30 2007-12-06 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
EP3260556B1 (de) 2006-05-31 2019-07-31 Sequenom, Inc. Verfahren zur nukleinsäureextraktion aus einer probe
EP2035439A4 (de) 2006-06-05 2010-01-13 Cancer Care Ontario Abschätzung des risikos von colorectalkrebs
US20080033985A1 (en) * 2006-06-09 2008-02-07 Gulfstream Bioinformatics Corporation Biomedical Information Modeling
US7700756B2 (en) * 2006-07-27 2010-04-20 Southern Illinois University Metabolic primers for the detection of perchlorate-reducing bacteria and methods of use thereof
US20080033819A1 (en) * 2006-07-28 2008-02-07 Ingenuity Systems, Inc. Genomics based targeted advertising
CA2660286A1 (en) 2006-08-09 2008-02-21 Homestead Clinical Corporation Organ-specific proteins and methods of their use
WO2008048120A2 (en) * 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
JP2010508815A (ja) 2006-11-02 2010-03-25 イエール・ユニバーシテイ 卵母細胞受容能の評価
NZ551157A (en) * 2006-11-08 2008-06-30 Rebecca Lee Roberts Method of identifying individuals at risk of thiopurine drug resistance and intolerance - GMPS
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
CA2673092A1 (en) * 2006-12-19 2008-06-26 Synergenz Bioscience Limited Methods and compositions for the assessment of cardiovascular function and disorders
CA2677000A1 (en) 2007-01-30 2008-08-07 Pharmacyclics, Inc. Methods for determining cancer resistance to histone deacetylase inhibitors
WO2008098142A2 (en) 2007-02-08 2008-08-14 Sequenom, Inc. Nucleic acid-based tests for rhd typing, gender determination and nucleic acid quantification
US9581595B2 (en) 2007-02-26 2017-02-28 Laboratory Corporation Of America Holdings Compositions and methods for determining whether a subject would benefit from co-receptor inhibitor therapy
CA2679954A1 (en) 2007-03-05 2008-09-12 Cancer Care Ontario Assessment of risk for colorectal cancer
WO2008118988A1 (en) 2007-03-26 2008-10-02 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US9580719B2 (en) * 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
CN101688213A (zh) 2007-04-27 2010-03-31 陶氏环球技术公司 用于快速筛选微生物宿主以鉴定某些在表达异源蛋白质方面具有改善的产量和/或质量的菌株的方法
US8200440B2 (en) 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
EP2195452B1 (de) 2007-08-29 2012-03-14 Sequenom, Inc. Verfahren und zusammensetzungen für die universelle grössenspezifische polymerasekettenreaktion
WO2009039190A1 (en) * 2007-09-17 2009-03-26 Gene Express, Inc. Cancer risk biomarker
WO2009128730A1 (en) 2008-01-25 2009-10-22 Patrick Gladding Methods and compositions for the assessment of drug response
WO2009114543A2 (en) 2008-03-11 2009-09-17 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
US9012370B2 (en) * 2008-03-11 2015-04-21 National Cancer Center Method for measuring chromosome, gene or specific nucleotide sequence copy numbers using SNP array
CA2718137A1 (en) 2008-03-26 2009-10-01 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
JP2011525106A (ja) * 2008-06-04 2011-09-15 ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティ・オブ・アリゾナ 瀰漫性ｂ大細胞型リンパ腫のマーカーおよびその使用方法
EP2631301B1 (de) 2008-08-18 2017-10-11 The Board of Trustees of the Leland Stanford Junior University Verfahren zur Bestimmung eines transplantattoleranten Phänotyps bei einer Person
US8476013B2 (en) * 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
JP5798037B2 (ja) 2008-11-06 2015-10-21 ユニバーシティ オブ マイアミ 蛋白尿腎疾患の病因における可溶性ｕＰＡＲの役割
US8039794B2 (en) * 2008-12-16 2011-10-18 Quest Diagnostics Investments Incorporated Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby
KR101025848B1 (ko) * 2008-12-30 2011-03-30 삼성전자주식회사 개인 유전체 통합 관리 방법 및 장치
BRPI1006075A2 (pt) 2009-01-07 2016-04-19 Myriad Genetics Inc biomarcadores de cancer
AU2010206843B2 (en) * 2009-01-20 2015-01-29 The Board Of Trustees Of The Leland Stanford Junior University Single cell gene expression for diagnosis, prognosis and identification of drug targets
JP2012517238A (ja) 2009-02-11 2012-08-02 カリス エムピーアイ インコーポレイテッド 腫瘍の分子プロファイリング法
US8832581B2 (en) * 2009-03-05 2014-09-09 Ming Zhang Gene expression browser for web-based search and visualization of characteristics of gene expression
WO2010107946A2 (en) * 2009-03-18 2010-09-23 Sequenom, Inc. Use of thermostable endonucleases for generating reporter molecules
WO2010115016A2 (en) 2009-04-03 2010-10-07 Sequenom, Inc. Nucleic acid preparation compositions and methods
EP2494077A4 (de) 2009-10-27 2013-08-21 Caris Mpi Inc Molekulare profilierung für personalisierte medizin
US20110201008A1 (en) * 2009-12-01 2011-08-18 University Of Miami Assays, methods and kits for measuring response to therapy and predicting clinical outcome in patients with b-cell lymphoma
WO2011068829A1 (en) 2009-12-02 2011-06-09 The Board Of Trustees Of The Leland Stanford Junior University Biomarkers for determining an allograft tolerant phenotype
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
DK2516680T3 (en) 2009-12-22 2016-05-02 Sequenom Inc Method and kits to identify aneuploidy
US9798855B2 (en) 2010-01-07 2017-10-24 Affymetrix, Inc. Differential filtering of genetic data
WO2011091435A2 (en) 2010-01-25 2011-07-28 Mount Sinai School Of Medicine Methods of treating liver disease
CA2794255C (en) 2010-03-25 2020-01-14 Minnie M. Sarwal Protein and gene biomarkers for rejection of organ transplants
EP2563380B1 (de) 2010-04-26 2018-05-30 aTyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten der cysteinyl-trna-synthetase
AU2011248614B2 (en) 2010-04-27 2017-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases
US8993723B2 (en) 2010-04-28 2015-03-31 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases
CA2797374C (en) 2010-04-29 2021-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases
EP2563383B1 (de) 2010-04-29 2017-03-01 Atyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von valyl-trna-synthetasen
CN103140233B (zh) 2010-05-03 2017-04-05 Atyr 医药公司 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
ES2623805T3 (es) 2010-05-03 2017-07-12 Atyr Pharma, Inc. Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de fenilalanil-alfa-ARNt sintetasas
WO2011139986A2 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases
JP6008844B2 (ja) 2010-05-04 2016-10-19 エータイアー ファーマ， インコーポレイテッド ｐ３８ＭＵＬＴＩ−ｔＲＮＡ合成酵素複合体のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
AU2011252990B2 (en) 2010-05-14 2017-04-20 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases
EP2575856B1 (de) 2010-05-27 2017-08-16 aTyr Pharma, Inc. Therapeutische, diagnostische und antikörperhaltige zusammensetzungen in zusammenhang mit proteinfragmenten von glutaminyl-trna-synthetasen
WO2011153277A2 (en) 2010-06-01 2011-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
CA2804391A1 (en) 2010-07-07 2012-01-12 Myriad Genetics, Inc. Gene signatures for cancer prognosis
WO2012021247A2 (en) 2010-07-12 2012-02-16 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
AU2011293294B2 (en) 2010-08-25 2016-03-24 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Tyrosyl-tRNA synthetases
WO2012033961A2 (en) * 2010-09-09 2012-03-15 Abbott Laboratories Systems and methods for displaying molecular probes and chromosomes
JP2013537045A (ja) 2010-09-15 2013-09-30 アルマック ダイアグノスティックス リミテッド 癌のための分子診断試験
WO2012149339A2 (en) 2011-04-29 2012-11-01 Sequenom, Inc. Quantification of a minority nucleic acid species
EP2807271B1 (de) 2012-01-24 2018-08-22 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
EP2814514B1 (de) 2012-02-16 2017-09-13 Atyr Pharma, Inc. Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen
SG11201405274WA (en) 2012-02-27 2014-10-30 Cellular Res Inc Compositions and kits for molecular counting
ES2776673T3 (es) 2012-02-27 2020-07-31 Univ North Carolina Chapel Hill Métodos y usos para etiquetas moleculares
US9605313B2 (en) 2012-03-02 2017-03-28 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
WO2014011928A1 (en) 2012-07-13 2014-01-16 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8766754B2 (en) 2012-07-18 2014-07-01 The Regents Of The University Of California Concave nanomagnets with widely tunable anisotropy
ES2938766T3 (es) 2012-11-16 2023-04-14 Myriad Genetics Inc Firmas génicas para el pronóstico de cáncer
WO2014085434A1 (en) 2012-11-27 2014-06-05 Pontificia Universidad Catolica De Chile Compositions and methods for diagnosing thyroid tumors
US9896728B2 (en) 2013-01-29 2018-02-20 Arcticrx Ltd. Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
EP3597774A1 (de) 2013-03-13 2020-01-22 Sequenom, Inc. Primer zur analyse der dna-methylierung
EP4043580A1 (de) 2013-03-15 2022-08-17 Myriad myPath, LLC Gene und gensignaturen zur diagnose und behandlung von melanomen
US10535420B2 (en) 2013-03-15 2020-01-14 Affymetrix, Inc. Systems and methods for probe design to detect the presence of simple and complex indels
KR101520615B1 (ko) 2013-03-20 2015-05-18 서울대학교산학협력단 간암 진단용 바이오 마커
US10390724B2 (en) 2013-06-26 2019-08-27 The Penn State Research Foundation Three-dimensional bio-medical probe sensing and contacting structures with addressibility and tunability
JP6463359B2 (ja) 2013-08-12 2019-01-30 ジェネンテック， インコーポレイテッド 補体関連病態を治療するための組成物及び方法
KR101527283B1 (ko) 2013-08-13 2015-06-10 서울대학교산학협력단 당단백질의 탈당화 검출을 통한 암 마커 스크리닝 방법 및 간세포암 마커
BR112016018205A8 (pt) 2014-02-08 2018-04-17 Genentech Inc métodos de tratamento de mal de alzheimer, de seleção de pacientes, de identificação de pacientes, de previsão, de otimização da eficácia terapêutica, kit, uso de agente e uso in vitro de agente
EP3117011B1 (de) 2014-03-13 2020-05-06 Sequenom, Inc. Verfahren und prozesse zur nicht-invasiven beurteilung genetischer variationen
JP6596442B2 (ja) 2014-04-22 2019-10-23 エンバイロロジックス インコーポレイテッド Ｄｎａ増幅を増強および／または予測するための組成物および方法
EP3143160B1 (de) 2014-05-13 2019-11-06 Myriad Genetics, Inc. Gensignaturen für krebsprognosen
WO2016003810A1 (en) 2014-07-02 2016-01-07 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
WO2016061252A1 (en) 2014-10-14 2016-04-21 The University Of North Carolina At Chapel Hill Methods and compositions for prognostic and/or diagnostic subtyping of pancreatic cancer
BR112017008082A2 (pt) 2014-10-20 2017-12-26 Envirologix Inc composições e métodos para detectar um vírus de rna
AU2015334841B2 (en) 2014-10-24 2022-02-03 Koninklijke Philips N.V. Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities
BR112017007962A2 (pt) 2014-10-24 2018-01-23 Koninklijke Philips Nv método implementado por computador, aparelho, mídia de armazenamento, programa de computador, kit, e, uso do kit
BR112017007965A8 (pt) 2014-10-24 2022-11-08 Koninklijke Philips Nv Método implantado por computador para inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; aparelho para inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; meio de armazenamento não transitório; programa de computador; kits para medir níveis de expressão de três ou mais genes-alvo da via de sinalização celular de tgf-b em uma amostra de um indivíduo; inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; e uso do kit
BR112017016350A2 (pt) 2015-01-30 2018-03-27 Envirologix Inc. molécula de substrato
US10953370B2 (en) 2015-02-05 2021-03-23 The Penn State Research Foundation Nano-pore arrays for bio-medical, environmental, and industrial sorting, filtering, monitoring, or dispensing
WO2016166800A1 (ja) * 2015-04-13 2016-10-20 国立研究開発法人産業技術総合研究所 実験データ記録装置、コンピュータプログラム、実験データ、実験データ記録方法、実験データ表示装置及び実験データ表示方法
GB201512869D0 (en) 2015-07-21 2015-09-02 Almac Diagnostics Ltd Gene signature for minute therapies
CN108136051A (zh) 2015-08-04 2018-06-08 Cd诊断股份有限公司 检测不良局部组织反应(altr)坏死的方法
KR102618536B1 (ko) * 2015-08-12 2023-12-27 삼성전자주식회사 환자의 개인화된 치료를 위한 돌연변이 우선순위화 방법 및 장치
US10720227B2 (en) * 2015-08-12 2020-07-21 Samsung Electronics Co., Ltd. Method and device for mutation prioritization for personalized therapy
JP7028763B2 (ja) 2015-08-14 2022-03-02 コーニンクレッカ フィリップス エヌ ヴェ 標的遺伝子発現の数学的モデリングを使用するＮＦｋＢ細胞シグナリング経路活性の評価
EP3362580B1 (de) 2015-10-18 2021-02-17 Affymetrix, Inc. Multiallele genotypisierung von einzelnukleotidpolymorphismen und indels
EP3377650A1 (de) 2015-11-19 2018-09-26 Susanne Wagner Signaturen zur vorhersage der krebsimmuntherapiereaktion
US9836444B2 (en) * 2015-12-10 2017-12-05 International Business Machines Corporation Spread cell value visualization
CA3010240A1 (en) 2016-01-06 2017-07-13 Alexander Gutin Genes and gene signatures for diagnosis and treatment of melanoma
US20190128895A1 (en) 2016-04-20 2019-05-02 Ldx Prognostics Limited Co. Methods and compositions for prognosing preterm birth
WO2017193062A1 (en) 2016-05-06 2017-11-09 Myriad Genetics, Inc. Gene signatures for renal cancer prognosis
JP6691617B2 (ja) 2016-05-17 2020-04-28 エルディエックス・プログノスティクス・リミテッド・カンパニーＬｄｘ Ｐｒｏｇｎｏｓｔｉｃｓ Ｌｉｍｉｔｅｄ Ｃｏ． 子癇前症の評価を提供するための方法及び組成物
CN106066948B (zh) * 2016-06-07 2018-09-28 北京大学 一种基因表达量的展现方法及装置
EP3532854A4 (de) * 2016-09-27 2020-10-14 BAE SYSTEMS Information and Electronic Systems Integration Inc. Verfahren zur implementierung eines tragbaren spektrumsanalysators
US20180165414A1 (en) * 2016-12-14 2018-06-14 FlowJo, LLC Applied Computer Technology for Management, Synthesis, Visualization, and Exploration of Parameters in Large Multi-Parameter Data Sets
KR102116178B1 (ko) 2017-05-10 2020-05-27 서울대학교산학협력단 간암 고위험군의 간암 발병 모니터링 또는 진단용 바이오마커 및 그 용도
CN110462372B (zh) 2017-05-25 2022-06-14 佛罗乔有限责任公司 大型多参数数据集的可视化、比较分析和自动差异检测
EP3461915A1 (de) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Beurteilung der aktivität von zellulären jak-stat1/2-signalisierungspfaden mittels mathematischer modellierung der zielgenexpression
EP3502279A1 (de) 2017-12-20 2019-06-26 Koninklijke Philips N.V. Beurteilung der aktivität von zellulären mapk-ap 1-signalisierungspfaden mittels mathematischer modellierung der zielgenexpression
EP3728321A1 (de) 2017-12-22 2020-10-28 F. Hoffmann-La Roche AG Verwendung von pilra-bindenden mitteln zur behandlung einer erkrankung
GB2574582A (en) * 2018-05-28 2019-12-18 Rainer Gabriel Schweiger Martin Method for simulating a technical device
EP3807648A2 (de) 2018-06-18 2021-04-21 Igenomix S.L. Verfahren zur beurteilung der endometrialen transformation
WO2020076897A1 (en) 2018-10-09 2020-04-16 Genecentric Therapeutics, Inc. Detecting cancer cell of origin
WO2020113237A1 (en) 2018-11-30 2020-06-04 Caris Mpi, Inc. Next-generation molecular profiling
JP2022529294A (ja) 2019-04-17 2022-06-20 アイジェノミクス、ソシエダッド、リミターダ 子宮平滑筋腫および平滑筋肉腫の早期診断のための改良方法
EP4069865A4 (de) 2019-12-02 2023-12-20 Caris MPI, Inc. Platinresistenztest für pan-krebs
WO2023178295A1 (en) 2022-03-18 2023-09-21 Ludwig Institute For Cancer Research Ltd Methods and systems for analyzing chromatins

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
NO870613L (no) 1986-03-05 1987-09-07 Molecular Diagnostics Inc Deteksjon av mikroorganismer i en prŸve inneholdende nukleinsyre.
US4740611A (en) * 1986-10-30 1988-04-26 The Standard Oil Company N,N'-disubstituted ureas
US4705864A (en) * 1986-11-10 1987-11-10 The Standard Oil Company Aryl oxime derivatives of hydantoins
WO1988004670A1 (en) 1986-12-20 1988-06-30 Kukita, Takeshi Bilirubin antigen, monoclonal antibody therefor, process for their preparation, and their use
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5525464A (en) 1987-04-01 1996-06-11 Hyseq, Inc. Method of sequencing by hybridization of oligonucleotide probes
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
WO1989011548A1 (en) 1988-05-20 1989-11-30 Cetus Corporation Immobilized sequence-specific probes
US5206137A (en) 1988-09-08 1993-04-27 Lifecodes Corporation Compositions and methods useful for genetic analysis
US6203977B1 (en) * 1988-11-15 2001-03-20 Yale University Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization
EP0392546A3 (de) 1989-04-14 1991-09-11 Ro Institut Za Molekularnu Genetiku I Geneticko Inzenjerstvo Verfahren zur Bestimmung von vollständigen oder partiellen Bestandteilen von sehr kurzen Sequenzen in Proben von Partikeln mikroskopischer Grösse mittels Hybridisierung mit Oligonukleotid-Sonden
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5871928A (en) * 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
DE69132843T2 (de) 1990-12-06 2002-09-12 Affymetrix Inc N D Ges D Staat Identifizierung von Nukleinsäuren in Proben
ATE244065T1 (de) 1990-12-06 2003-07-15 Affymetrix Inc Verfahren und reagenzien für immobilisierten polymersynthese in sehr grossem masstab
GR1000797B (el) 1991-06-10 1993-01-25 Emmanouil E Petromanolakis Αποσβεστηρας ενεργειας κυματισμου κατα την προωση ενος πλοιου.
ATE185596T1 (de) * 1991-08-13 1999-10-15 Wisconsin Milk Marketing Board Dna-sequenz, die für rinder-g(a)-lactalbumin kodiert, und nutzungsmethoden
US5846717A (en) * 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
CA2134552A1 (en) 1992-04-27 1993-11-11 George D. Sorenson Detection of gene sequences in biological fluids
US6251920B1 (en) * 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) * 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5524070A (en) * 1992-10-07 1996-06-04 The Research Foundation Of State University Of New York Local adaptive contrast enhancement
WO1995011995A1 (en) 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US5632282A (en) * 1993-07-20 1997-05-27 Hay; S. Hutson Ocular disease detection apparatus
ES2176308T3 (es) 1993-10-28 2002-12-01 Houston Advanced Res Ct Dispositivo de microestructura porosa que permite un flujo.
US6096503A (en) * 1993-11-12 2000-08-01 The Scripps Research Institute Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
US6339767B1 (en) * 1997-06-02 2002-01-15 Aurigin Systems, Inc. Using hyperbolic trees to visualize data generated by patent-centric and group-oriented data processing
EP0667586A3 (de) * 1994-02-14 1996-08-28 Digital Equipment Corp System zur Erzeugung von Datenbanken.
US5560005A (en) * 1994-02-25 1996-09-24 Actamed Corp. Methods and systems for object-based relational distributed databases
US5571639A (en) * 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5570291A (en) * 1994-08-24 1996-10-29 Wallace Computer Services, Inc. Custom product estimating and order processing system
US6600996B2 (en) 1994-10-21 2003-07-29 Affymetrix, Inc. Computer-aided techniques for analyzing biological sequences
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
WO1997027317A1 (en) 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
EP0805874A4 (de) 1995-01-27 1998-05-20 Incyte Pharma Inc Computersystem zum speichern und analysieren von mikrobiologischen daten
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
EP0747418B1 (de) * 1995-06-06 2002-07-03 Ube Industries, Ltd. Aromatische Polyimid und Gastrennung
US5707806A (en) 1995-06-07 1998-01-13 Genzyme Corporation Direct sequence identification of mutations by cleavage- and ligation-associated mutation-specific sequencing
US5777888A (en) 1995-08-09 1998-07-07 Regents Of The University Of California Systems for generating and analyzing stimulus-response output signal matrices
US5871697A (en) 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
GB9522615D0 (en) 1995-11-03 1996-01-03 Pharmacia Spa 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
US5778200A (en) 1995-11-21 1998-07-07 Advanced Micro Devices, Inc. Bus arbiter including aging factor counters to dynamically vary arbitration priority
AU2189397A (en) 1996-02-08 1997-08-28 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US6108635A (en) * 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US6295514B1 (en) * 1996-11-04 2001-09-25 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for representing similarity/dissimilarity between chemical compounds
US5968784A (en) * 1997-01-15 1999-10-19 Chugai Pharmaceutical Co., Ltd. Method for analyzing quantitative expression of genes
US6205447B1 (en) * 1997-06-30 2001-03-20 International Business Machines Corporation Relational database management of multi-dimensional data
WO1999005324A1 (en) * 1997-07-25 1999-02-04 Affymetrix, Inc. System for providing a polymorphism database
US6032151A (en) * 1997-11-17 2000-02-29 Sun Microsystems, Inc. Database system employing polymorphic entry and entry matching
US6025194A (en) * 1997-11-19 2000-02-15 Geron Corporation Nucleic acid sequence of senescence asssociated gene
US5991766A (en) * 1997-12-02 1999-11-23 Electronic Data Systems Corporation Method and system for managing redundant objects in a distributed object system
US20030036855A1 (en) * 1998-03-16 2003-02-20 Praelux Incorporated, A Corporation Of New Jersey Method and apparatus for screening chemical compounds
US6324533B1 (en) * 1998-05-29 2001-11-27 International Business Machines Corporation Integrated database and data-mining system
AU2342900A (en) * 1998-09-23 2000-05-01 Cleveland Clinic Foundation, The Novel interferon stimulated and repressed genes
US6140054A (en) * 1998-09-30 2000-10-31 University Of Utah Research Foundation Multiplex genotyping using fluorescent hybridization probes
US6251601B1 (en) * 1999-02-02 2001-06-26 Vysis, Inc. Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays
US6284465B1 (en) * 1999-04-15 2001-09-04 Agilent Technologies, Inc. Apparatus, systems and method for locating nucleic acids bound to surfaces
US6338071B1 (en) * 1999-08-18 2002-01-08 Affymetrix, Inc. Method and system for providing a contract management system using an action-item table
US6754666B1 (en) * 1999-08-19 2004-06-22 A2I, Inc. Efficient storage and access in a database management system
WO2001014328A2 (en) * 1999-08-20 2001-03-01 Merck & Co., Inc. Substituted ureas as cell adhesion inhibitors
US7072896B2 (en) * 2000-02-16 2006-07-04 Verizon Laboratories Inc. System and method for automatic loading of an XML document defined by a document-type definition into a relational database including the generation of a relational schema therefor
US6569615B1 (en) * 2000-04-10 2003-05-27 The United States Of America As Represented By The Department Of Veteran's Affairs Composition and methods for tissue preservation
US20020062258A1 (en) * 2000-05-18 2002-05-23 Bailey Steven C. Computer-implemented procurement of items using parametric searching
US7731904B2 (en) * 2000-09-19 2010-06-08 Canon Kabushiki Kaisha Method for making probe support and apparatus used for the method
WO2003012046A2 (en) * 2001-07-27 2003-02-13 The Regents Of The University Of California Stk15 (stk6) gene polymorphism and methods of determining cancer risk
US20030126139A1 (en) * 2001-12-28 2003-07-03 Lee Timothy A. System and method for loading commercial web sites

Also Published As

Publication number Publication date
US6229911B1 (en) 2001-05-08
US7215804B2 (en) 2007-05-08
US6882742B2 (en) 2005-04-19
US20030074363A1 (en) 2003-04-17
WO1999005591A2 (en) 1999-02-04
JP2001511529A (ja) 2001-08-14
EP1007737A1 (de) 2000-06-14
US20020062319A1 (en) 2002-05-23
JP2001511546A (ja) 2001-08-14
WO1999005324A1 (en) 1999-02-04
EP1002264A2 (de) 2000-05-24
EP1002264A4 (de) 2002-07-03
US6308170B1 (en) 2001-10-23
US6188783B1 (en) 2001-02-13
EP1009861A4 (de) 2002-10-16
EP1009861A1 (de) 2000-06-21
US6567540B2 (en) 2003-05-20
WO1999005591A3 (en) 1999-05-20
US20050164270A1 (en) 2005-07-28
US20050157915A1 (en) 2005-07-21
DE69823206T2 (de) 2004-08-19
JP2005100389A (ja) 2005-04-14
JP2005353057A (ja) 2005-12-22
ATE264523T1 (de) 2004-04-15
EP1002264B1 (de) 2004-04-14
JP3776728B2 (ja) 2006-05-17
EP0998697A4 (de) 2002-07-24
US20020012456A1 (en) 2002-01-31
WO1999005574A1 (en) 1999-02-04
US20030125882A1 (en) 2003-07-03
US6532462B2 (en) 2003-03-11
EP0998697A1 (de) 2000-05-10
WO1999005323A1 (en) 1999-02-04
JP2001511550A (ja) 2001-08-14
US6484183B1 (en) 2002-11-19
EP1007737A4 (de) 2002-07-03
JP2001515234A (ja) 2001-09-18

Similar Documents

Publication Publication Date Title
DE69823206D1 (de) Verfahren zur herstellung einer bio-informatik-datenbank
BR0214367A (pt) métodos implementados em computador para a análise de dados de imagem, para criar um relatório pertencendo à análise de diagnóstico de dados de imagem, e para análise de uma imagem, sistema para a análise de dados de imagem, e, sistema de computador para análise de uma imagem
ATE98773T1 (de) Verfahren zur optischen analyse.
DE3689856T2 (de) Analyseverfahren und vorrichtung für biologische specimen.
WO2003021525A3 (de) Verfahren zur entnahme einer probe aus einem system
DE3875456T3 (de) Verfahren zur Analyse hämatopoietischer Zellen in einer Probe.
DE58909018D1 (de) Testträger für die Analyse einer Probenflüssigkeit, Verfahren zur Durchführung einer solchen Analyse und Herstellungsverfahren.
ATA242687A (de) Verfahren zur herstellung eines antioxidationsmittels, insbesondere zur verwendung als arzneimittel
BR0113662A (pt) Sistema de avaliação analìtica de materiais e geração de relatórios
DE3769002D1 (de) Verfahren und vorrichtung zur ummantelung eines optischen vorform-stabes.
ATE318930T1 (de) Nukleinsäuresonden zur detektion von candida- spezies
AT386222B (de) Verfahren und vorrichtung zur herstellung eines als kraft- bzw. brennstoff geeigneten fettsaeureestergemisches
EP0723156A3 (de) Verfahren zur Normalisierung eines Testverfahrens
WO2003058499A1 (fr) Appareil et procede de recherche de connaissance, programme et support d'enregistrement associes
DE69000071D1 (de) Vorrichtung zur dynamischen torsionspruefung einer probe.
EP1396800A3 (de) Verfahren und Vorrichtung zur Herstellung einer Bio-Informatik-Datenbank
Craig Jr et al. State-space formulation of multi-shaker modal analysis
SE9601812D0 (sv) Improvements in, or Relating to, Speech-To-Speech Conversion
Hummel et al. Changes in the reproductive cycle of the cockle Cerastoderma edule after disturbance by means of tidal manipulation
AU3535389A (en) Method for diagnosis of infectious diseases and method of detecting and identifying microorganisms
WO1988004454A3 (en) Information retrieval system and method
DE59010149D1 (de) Vorrichtung zur Vorbereitung von Gasproben für die Analyse
Kennedy et al. Functional structure in sentences: A performance analysis
赵右更 et al. PRENATAL DIAGNOSIS Ⅱ. AMNIOTIC FLUID ACETYLCHOLINESTERASE ISOENZYME PATTERNS AND ALPHA-FETOPROTEIN FOR PRENATAL DIAGNOSIS
DE69011917T2 (de) Vorrichtung für die automatische Gültigkeitsanalyse von medizinischen Prüfdaten.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition