DE69806499T2 - Serpentinenförmiger elektroforetischer kanal mit selbstkorrigierenden kurven - Google Patents

Serpentinenförmiger elektroforetischer kanal mit selbstkorrigierenden kurven

Info

Publication number
DE69806499T2
DE69806499T2 DE69806499T DE69806499T DE69806499T2 DE 69806499 T2 DE69806499 T2 DE 69806499T2 DE 69806499 T DE69806499 T DE 69806499T DE 69806499 T DE69806499 T DE 69806499T DE 69806499 T2 DE69806499 T2 DE 69806499T2
Authority
DE
Germany
Prior art keywords
channel
angle
serpentine
alpha
curved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69806499T
Other languages
English (en)
Other versions
DE69806499D1 (de
Inventor
S Nordman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
PE Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PE Corp filed Critical PE Corp
Publication of DE69806499D1 publication Critical patent/DE69806499D1/de
Application granted granted Critical
Publication of DE69806499T2 publication Critical patent/DE69806499T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N2030/285—Control of physical parameters of the fluid carrier electrically driven carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S366/00—Agitating
    • Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
DE69806499T 1997-11-12 1998-11-12 Serpentinenförmiger elektroforetischer kanal mit selbstkorrigierenden kurven Expired - Lifetime DE69806499T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6510097P 1997-11-12 1997-11-12
PCT/US1998/024202 WO1999024828A1 (en) 1997-11-12 1998-11-12 Serpentine electrophoresis channel with self-correcting bends

Publications (2)

Publication Number Publication Date
DE69806499D1 DE69806499D1 (de) 2002-08-14
DE69806499T2 true DE69806499T2 (de) 2003-02-27

Family

ID=22060347

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69806499T Expired - Lifetime DE69806499T2 (de) 1997-11-12 1998-11-12 Serpentinenförmiger elektroforetischer kanal mit selbstkorrigierenden kurven

Country Status (8)

Country Link
US (1) US6176991B1 (de)
EP (1) EP1031032B1 (de)
JP (1) JP2001523001A (de)
AT (1) ATE220456T1 (de)
AU (1) AU747940B2 (de)
CA (1) CA2307623C (de)
DE (1) DE69806499T2 (de)
WO (1) WO1999024828A1 (de)

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US7867193B2 (en) * 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
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US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
DE10303107B3 (de) * 2003-01-27 2004-09-16 Sls Micro Technology Gmbh Trennsäule, insbesondere für einen miniaturisierten Gaschromatographen
US8142630B2 (en) * 2003-05-19 2012-03-27 Protasis Corporation Electrophoresis devices and methods for focusing charged analytes
US7435381B2 (en) * 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US7160025B2 (en) * 2003-06-11 2007-01-09 Agency For Science, Technology And Research Micromixer apparatus and methods of using same
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
JP2005024316A (ja) * 2003-06-30 2005-01-27 Kyocera Corp マイクロ化学チップおよびその製造方法
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
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US7867194B2 (en) 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
US20060285433A1 (en) * 2005-06-20 2006-12-21 Jing-Tang Yang Fluidic mixer of serpentine channel incorporated with staggered sudden-expansion and convergent cross sections
WO2007024485A2 (en) * 2005-08-11 2007-03-01 Eksigent Technologies, Llc Microfluidic reduction of diffusion and complience effect in a fluid mixing region
US20070246106A1 (en) * 2006-04-25 2007-10-25 Velocys Inc. Flow Distribution Channels To Control Flow in Process Channels
WO2008094672A2 (en) 2007-01-31 2008-08-07 Charles Stark Draper Laboratory, Inc. Membrane-based fluid control in microfluidic devices
JP2008212814A (ja) * 2007-03-02 2008-09-18 Canon Inc 流体搬送路、流体処理装置および流体処理システム
US8186913B2 (en) * 2007-04-16 2012-05-29 The General Hospital Corporation Systems and methods for particle focusing in microchannels
JP4411661B2 (ja) * 2007-10-26 2010-02-10 セイコーエプソン株式会社 生体物質検出方法
US8430558B1 (en) * 2008-09-05 2013-04-30 University Of Central Florida Research Foundation, Inc. Microfluidic mixer having channel width variation for enhanced fluid mixing
US8377277B2 (en) 2008-10-22 2013-02-19 General Electric Company System and method for performing microfluidic manipulation
JP5008690B2 (ja) 2009-03-31 2012-08-22 信和化工株式会社 マイクロ流路デバイス及びマイクロ流路デバイスの作製方法
AU2010257118B2 (en) * 2009-06-04 2014-08-28 Lockheed Martin Corporation Multiple-sample microfluidic chip for DNA analysis
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US8795605B2 (en) * 2012-01-12 2014-08-05 Fred C. Senftleber Apparatus and methods for transferring materials between locations possessing different cross-sectional areas with minimal band spreading and dispersion due to unequal path-lengths
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CN102788831B (zh) * 2012-08-13 2014-07-30 中国科学院研究生院 分离后可调节pH的微流控芯片电泳-电化学检测装置及其应用
US20140065034A1 (en) * 2012-08-31 2014-03-06 Yun Zheng Microfluidic device and method of fabricating microfluidic devices
CN106596692B (zh) * 2017-01-14 2018-12-28 常州大学 一种弯曲毛细管电泳检测抗体多肽相互作用的方法
WO2022241247A1 (en) * 2021-05-13 2022-11-17 Fluid-Screen, Inc. Microfluidic device with improved flow profile

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Also Published As

Publication number Publication date
CA2307623C (en) 2004-03-16
DE69806499D1 (de) 2002-08-14
CA2307623A1 (en) 1999-05-20
EP1031032B1 (de) 2002-07-10
EP1031032A1 (de) 2000-08-30
AU747940B2 (en) 2002-05-30
ATE220456T1 (de) 2002-07-15
AU1458099A (en) 1999-05-31
JP2001523001A (ja) 2001-11-20
US6176991B1 (en) 2001-01-23
WO1999024828A1 (en) 1999-05-20

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: APPLERA CORP., FOSTER CITY, CALIF., US

8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

Free format text: PFANDRECHT

8380 Miscellaneous part iii

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