DE69800630T2 - Chip zur elektroforetischen Trennung von Molekülen und Verfahren zur Verwendung desselben - Google Patents
Chip zur elektroforetischen Trennung von Molekülen und Verfahren zur Verwendung desselbenInfo
- Publication number
- DE69800630T2 DE69800630T2 DE69800630T DE69800630T DE69800630T2 DE 69800630 T2 DE69800630 T2 DE 69800630T2 DE 69800630 T DE69800630 T DE 69800630T DE 69800630 T DE69800630 T DE 69800630T DE 69800630 T2 DE69800630 T2 DE 69800630T2
- Authority
- DE
- Germany
- Prior art keywords
- molecules
- chip
- same
- electrophoretic separation
- electrophoretic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Electrostatic Separation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98114135A EP0977030B1 (de) | 1998-07-29 | 1998-07-29 | Chip zur elektroforetischen Trennung von Molekülen und Verfahren zur Verwendung desselben |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69800630D1 DE69800630D1 (de) | 2001-04-26 |
DE69800630T2 true DE69800630T2 (de) | 2001-08-23 |
Family
ID=8232360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69800630T Expired - Fee Related DE69800630T2 (de) | 1998-07-29 | 1998-07-29 | Chip zur elektroforetischen Trennung von Molekülen und Verfahren zur Verwendung desselben |
Country Status (3)
Country | Link |
---|---|
US (1) | US6254754B1 (de) |
EP (1) | EP0977030B1 (de) |
DE (1) | DE69800630T2 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004059878A1 (de) * | 2004-12-10 | 2006-06-22 | Humboldt-Universität Zu Berlin | Verfahren zum elektrophoretischen Trennen einer Partikelfraktion |
Families Citing this family (64)
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CA2255599C (en) | 1996-04-25 | 2006-09-05 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
US6540896B1 (en) * | 1998-08-05 | 2003-04-01 | Caliper Technologies Corp. | Open-Field serial to parallel converter |
US6451264B1 (en) * | 2000-01-28 | 2002-09-17 | Roche Diagnostics Corporation | Fluid flow control in curved capillary channels |
EP1261862A2 (de) * | 2000-02-22 | 2002-12-04 | California Institute of Technology | Entwicklung eines auf selbstproduzierten nanoarrays basierenden gelfreien molekularsiebes |
US7892854B2 (en) | 2000-06-21 | 2011-02-22 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
JP2002184775A (ja) * | 2000-12-19 | 2002-06-28 | Mitsubishi Electric Corp | 柱状構造物を備えた構造体、その製造方法及びそれを用いたdna分離デバイス |
WO2002050095A1 (en) * | 2000-12-18 | 2002-06-27 | Trustees Of Princeton University | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis |
WO2002065515A2 (en) * | 2001-02-14 | 2002-08-22 | Science & Technology Corporation @ Unm | Nanostructured devices for separation and analysis |
DE10113257C1 (de) * | 2001-03-19 | 2002-11-14 | Inst Mikrotechnik Mainz Gmbh | Elektrophoresevorrichtung und ihre Verwendung |
US6706163B2 (en) * | 2001-03-21 | 2004-03-16 | Michael Seul | On-chip analysis of particles and fractionation of particle mixtures using light-controlled electrokinetic assembly of particles near surfaces |
US7014747B2 (en) * | 2001-06-20 | 2006-03-21 | Sandia Corporation | Dielectrophoretic systems without embedded electrodes |
US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
WO2003008977A2 (en) * | 2001-07-16 | 2003-01-30 | Protein, Forest, Inc. | Arrays of buffers for analysing biomolecules by their isoelectric point |
KR20040068122A (ko) | 2001-10-15 | 2004-07-30 | 바이오어레이 솔루션스 리미티드 | 공동 검색과 효소-매개된 탐지에 의한 다형성 좌위의 다중분석 |
US7597791B2 (en) * | 2001-10-19 | 2009-10-06 | The Trustees Of Princeton University | Method and apparatus for generating electric fields and flow distributions for rapidly separating molecules |
WO2003054517A2 (en) * | 2001-12-19 | 2003-07-03 | Biogen Idec Ma Inc. | Methods for detecting half-antibodies using chip-based gel electrophoresis |
WO2003071263A1 (en) * | 2002-02-19 | 2003-08-28 | Genome Institute Of Singapore, National University Of Singapore | Device for isoelectric focussing |
US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
GB0212853D0 (en) * | 2002-06-01 | 2002-07-17 | Novartis Pharma Ag | Separation of molecules |
SE0201738D0 (sv) * | 2002-06-07 | 2002-06-07 | Aamic Ab | Micro-fluid structures |
US20050238506A1 (en) * | 2002-06-21 | 2005-10-27 | The Charles Stark Draper Laboratory, Inc. | Electromagnetically-actuated microfluidic flow regulators and related applications |
US7867193B2 (en) * | 2004-01-29 | 2011-01-11 | The Charles Stark Draper Laboratory, Inc. | Drug delivery apparatus |
JP3725109B2 (ja) * | 2002-09-19 | 2005-12-07 | 財団法人生産技術研究奨励会 | マイクロ流体デバイス |
US7526114B2 (en) | 2002-11-15 | 2009-04-28 | Bioarray Solutions Ltd. | Analysis, secure access to, and transmission of array images |
US7094354B2 (en) * | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
US7435381B2 (en) * | 2003-05-29 | 2008-10-14 | Siemens Healthcare Diagnostics Inc. | Packaging of microfluidic devices |
US20080257754A1 (en) * | 2003-06-27 | 2008-10-23 | Pugia Michael J | Method and apparatus for entry of specimens into a microfluidic device |
US20040265171A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method for uniform application of fluid into a reactive reagent area |
US20040265172A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method and apparatus for entry and storage of specimens into a microfluidic device |
KR100538469B1 (ko) * | 2003-07-18 | 2005-12-23 | 한국과학기술원 | 미소 기둥형 구조물과 교차 전기장을 이용한 생물학적 분석 기기 및 그 방법과, 생물학적 분석 시스템 |
US7347617B2 (en) * | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
CN1867831A (zh) * | 2003-09-12 | 2006-11-22 | 日本电气株式会社 | 芯片、使用该芯片的设备、以及使用该设备的方法 |
WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
CA2539824C (en) | 2003-09-22 | 2015-02-03 | Xinwen Wang | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
US20070119712A1 (en) * | 2003-09-24 | 2007-05-31 | Agilent Technologies, Inc. | Electrophoretic separation of amphoteric molecules |
AU2004286252A1 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
WO2005045060A2 (en) | 2003-10-29 | 2005-05-19 | Bioarray Solutions, Ltd. | Multiplexed nucleic acid analysis by fragmentation of double-stranded dna |
US20070275481A1 (en) * | 2003-11-24 | 2007-11-29 | Biogen Idec Ma Inc. | Methods For Detecting Half-Antibodies Using Chip Based Gel Electophoresis |
US7867194B2 (en) | 2004-01-29 | 2011-01-11 | The Charles Stark Draper Laboratory, Inc. | Drug delivery apparatus |
JP3952036B2 (ja) * | 2004-05-13 | 2007-08-01 | コニカミノルタセンシング株式会社 | マイクロ流体デバイス並びに試液の試験方法および試験システム |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
US20060051265A1 (en) * | 2004-09-08 | 2006-03-09 | Health Research, Inc. | Apparatus and method for sorting microstructures in a fluid medium |
WO2006083846A2 (en) * | 2005-02-01 | 2006-08-10 | Sigma-Aldrich Co. | Detection of polyamino acids using trimethincyanine dyes |
US7704360B2 (en) * | 2005-03-14 | 2010-04-27 | Agilent Technologies, Inc. | Devices and methods for separating sample constituents |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
KR100813254B1 (ko) | 2006-05-29 | 2008-03-13 | 삼성전자주식회사 | 유전 영동을 통하여 분극성 분석물을 분리하기 위한 장치및 그를 이용하여 시료 중의 분극성 물질을 분리하는 방법 |
WO2008094672A2 (en) | 2007-01-31 | 2008-08-07 | Charles Stark Draper Laboratory, Inc. | Membrane-based fluid control in microfluidic devices |
US8652420B2 (en) | 2007-05-23 | 2014-02-18 | Vrije Universiteit Brussel | Device for the distribution of sample and carrier liquid across a micro-fabricated separation channel |
US8702946B1 (en) * | 2007-05-31 | 2014-04-22 | Sandia Corporation | Dielectrokinetic chromatography and devices thereof |
FR2930900B1 (fr) * | 2008-05-06 | 2010-09-10 | Commissariat Energie Atomique | Dispositif de separation de biomolecules d'un fluide |
JP4798183B2 (ja) * | 2008-08-04 | 2011-10-19 | 日本電気株式会社 | 電気泳動チップ |
JP2012531256A (ja) * | 2009-06-24 | 2012-12-10 | ステイト オブ オレゴン アクティング バイ アンド スルー ザ ステイト ボード オブ ハイヤー エデュケーション オン ビハーフ オブ オレゴン ステイト ユニバーシティー | 透析用マイクロ流体デバイス |
US8753515B2 (en) | 2009-12-05 | 2014-06-17 | Home Dialysis Plus, Ltd. | Dialysis system with ultrafiltration control |
US8501009B2 (en) | 2010-06-07 | 2013-08-06 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Fluid purification system |
US8876795B2 (en) | 2011-02-02 | 2014-11-04 | The Charles Stark Draper Laboratory, Inc. | Drug delivery apparatus |
CA2832494C (en) | 2011-04-06 | 2019-11-26 | Ortho-Clinical Diagnostics, Inc. | Assay device having rhombus-shaped projections |
ES2640953T3 (es) | 2011-10-07 | 2017-11-07 | Outset Medical, Inc. | Purificación de líquido de intercambio de calor para un sistema de diálisis |
US8917096B2 (en) | 2012-11-15 | 2014-12-23 | International Business Machines Corporation | Determination of isoelectric points of biomolecules using capacitive sensors |
ES2864727T3 (es) | 2014-04-29 | 2021-10-14 | Outset Medical Inc | Sistema y métodos de diálisis |
WO2016044710A1 (en) * | 2014-09-18 | 2016-03-24 | Massachusetts Institute Of Technology | One-step protein analysis using slanted nanofilter array |
CN108368469A (zh) * | 2015-10-07 | 2018-08-03 | 加利福尼亚大学校董会 | 石墨烯系多模态传感器 |
JP7025408B2 (ja) | 2016-08-19 | 2022-02-24 | アウトセット・メディカル・インコーポレイテッド | 腹膜透析システム及び方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4812216A (en) * | 1987-08-28 | 1989-03-14 | Bios Corporation | Method of handling and transporting a transfer membrane used in a blotting apparatus |
US5750015A (en) * | 1990-02-28 | 1998-05-12 | Soane Biosciences | Method and device for moving molecules by the application of a plurality of electrical fields |
US5427663A (en) * | 1993-06-08 | 1995-06-27 | British Technology Group Usa Inc. | Microlithographic array for macromolecule and cell fractionation |
US5449446A (en) * | 1994-03-09 | 1995-09-12 | Verma; Sumeet | Multi-purpose electrophoresis apparatus |
-
1998
- 1998-07-29 EP EP98114135A patent/EP0977030B1/de not_active Expired - Lifetime
- 1998-07-29 DE DE69800630T patent/DE69800630T2/de not_active Expired - Fee Related
-
1999
- 1999-07-26 US US09/361,063 patent/US6254754B1/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004059878A1 (de) * | 2004-12-10 | 2006-06-22 | Humboldt-Universität Zu Berlin | Verfahren zum elektrophoretischen Trennen einer Partikelfraktion |
Also Published As
Publication number | Publication date |
---|---|
DE69800630D1 (de) | 2001-04-26 |
EP0977030A1 (de) | 2000-02-02 |
EP0977030B1 (de) | 2001-03-21 |
US6254754B1 (en) | 2001-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: AGILENT TECHNOLOGIES, INC., PALO ALTO, CALIF., US |
|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: AGILENT TECHNOLOGIES, INC. (N.D.GES.D.STAATES DELA |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: AGILENT TECHNOLOGIES, INC. (N.D.GES.D. STAATES, US |
|
8339 | Ceased/non-payment of the annual fee |