DE69735375D1 - Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung - Google Patents

Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung

Info

Publication number
DE69735375D1
DE69735375D1 DE69735375T DE69735375T DE69735375D1 DE 69735375 D1 DE69735375 D1 DE 69735375D1 DE 69735375 T DE69735375 T DE 69735375T DE 69735375 T DE69735375 T DE 69735375T DE 69735375 D1 DE69735375 D1 DE 69735375D1
Authority
DE
Germany
Prior art keywords
sarp
peptides
apoptosis
production
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69735375T
Other languages
English (en)
Other versions
DE69735375T2 (de
DE69735375T3 (de
Inventor
Samuil Umansky
Hovsep Melkonyan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GENTECH, INC., SAN FRANCISCO, CALIF., US
Original Assignee
Tanox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26701439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69735375(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tanox Inc filed Critical Tanox Inc
Application granted granted Critical
Publication of DE69735375D1 publication Critical patent/DE69735375D1/de
Publication of DE69735375T2 publication Critical patent/DE69735375T2/de
Publication of DE69735375T3 publication Critical patent/DE69735375T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DE69735375T 1996-09-24 1997-09-24 Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung Expired - Lifetime DE69735375T3 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2660396P 1996-09-24 1996-09-24
US26603P 1996-09-24
US2836396P 1996-10-11 1996-10-11
US28363P 1996-10-11
PCT/US1997/017154 WO1998013493A2 (en) 1996-09-24 1997-09-24 A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof

Publications (3)

Publication Number Publication Date
DE69735375D1 true DE69735375D1 (de) 2006-04-27
DE69735375T2 DE69735375T2 (de) 2006-11-30
DE69735375T3 DE69735375T3 (de) 2010-09-02

Family

ID=26701439

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735375T Expired - Lifetime DE69735375T3 (de) 1996-09-24 1997-09-24 Genfamilie von apoptose-verwandten peptiden, dadurch kodierte peptide und verfahren zu deren herstellung

Country Status (11)

Country Link
US (3) US6433155B1 (de)
EP (1) EP0932678B2 (de)
JP (2) JP4299886B2 (de)
AT (1) ATE318915T1 (de)
AU (1) AU737323B2 (de)
CA (1) CA2266325C (de)
DE (1) DE69735375T3 (de)
DK (1) DK0932678T4 (de)
ES (1) ES2263181T5 (de)
PT (1) PT932678E (de)
WO (1) WO1998013493A2 (de)

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EP0879885A1 (de) * 1997-05-23 1998-11-25 Smithkline Beecham Corporation GEN für ein sekretiertes-Maus-sFRP-1-Protein ähnliches Protein
AU7704498A (en) 1997-05-29 1998-12-30 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Human frp and fragments thereof including methods for using them
US20030203446A1 (en) * 1998-10-07 2003-10-30 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CN1413257A (zh) * 1998-10-30 2003-04-23 内布拉斯加大学林肯分校 细胞凋亡基因的跨种转移和由此产生的转基因植物
GB9921009D0 (en) * 1999-09-07 1999-11-10 Neuropa Ltd Essential genes and assays relating thereto
US20080166356A9 (en) * 1999-09-13 2008-07-10 Peter Bodine Pharmaceutical compositions and methods of using secreted frizzled related protein
US6600018B1 (en) * 2000-04-10 2003-07-29 The United States Of America As Represented By The Department Of Health And Human Services Secreted frizzled related protein, sFRP, fragments and methods of use thereof
HUP0302738A3 (en) * 2000-12-06 2010-01-28 Serono Lab Use of sarp-1 for the treatment and/or prevention of scleroderma
CA2434672C (en) 2001-01-10 2014-03-25 Jeffrey S. Rubin Sfrp and peptide motifs that interact with sfrp and methods of their use
EP1222933A1 (de) * 2001-01-15 2002-07-17 Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum Bildung und/oder Reduktion von neuem Lungengewebe in einer erkranketen Lunge, durch Modulierung des Wnt-Signalwegs
US20030044409A1 (en) * 2001-05-01 2003-03-06 Carson Dennis A. Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens
WO2002088081A2 (en) 2001-05-01 2002-11-07 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
US7879544B2 (en) * 2002-07-29 2011-02-01 Hmgene Inc. Methods of identifying adipocyte specific genes, the genes identified, and their uses
US20050054599A1 (en) * 2003-05-02 2005-03-10 Coles John G. Biosynthetic platform for cardioprotective stress response in human fetal heart tissue
JP2008500022A (ja) * 2003-12-16 2008-01-10 アベンティス・ファーマスーティカルズ・インコーポレイテツド 分泌型神経アポトーシス阻害タンパク質
KR101652854B1 (ko) 2004-07-23 2016-08-31 퍼시픽 에지 리미티드 방광암 검출용 소변 표지
WO2007022515A2 (en) 2005-08-19 2007-02-22 Duke University Stem cell derived factors for treating pathologic conditions
US7723477B2 (en) * 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
ES2618785T3 (es) * 2005-10-31 2017-06-22 Oncomed Pharmaceuticals, Inc. Composiciones y métodos para tratar el cáncer basados en receptores FZD humanos
NZ545243A (en) 2006-02-10 2009-07-31 Pacific Edge Biotechnology Ltd Urine gene expression ratios for detection of cancer
JP2010504081A (ja) * 2006-09-08 2010-02-12 ジェネンテック インコーポレイテッド Ｗｎｔ拮抗体ならびにｗｎｔ媒介障害の診断および処置におけるｗｎｔ拮抗体の使用
CN105079805A (zh) 2008-09-26 2015-11-25 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Ｗｎｔ拮抗劑及治療和篩選方法
CN102971337B (zh) 2010-04-01 2016-09-21 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
DK3590949T3 (da) 2010-10-01 2022-07-11 Modernatx Inc Ribonukleinsyrer indeholdende n1-methyl-pseudouracil og anvendelse heraf
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
SG10201602654SA (en) 2011-10-03 2016-05-30 Moderna Therapeutics Inc Modified nucleosides,nucleotides,and nucleic acids,and uses thereof
WO2013090648A1 (en) 2011-12-16 2013-06-20 modeRNA Therapeutics Modified nucleoside, nucleotide, and nucleic acid compositions
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
JP2015516143A (ja) 2012-04-02 2015-06-08 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ヒト疾患に関連するタンパク質の産生のための修飾ポリヌクレオチド
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
WO2014066328A1 (en) 2012-10-23 2014-05-01 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using wnt pathway-binding agents
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
CN105073195A (zh) 2013-02-04 2015-11-18 昂科梅德制药有限公司 使用Wnt途径抑制剂进行治疗的方法及对该治疗的监测
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
AU2014329452B2 (en) 2013-10-03 2019-06-20 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor

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NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
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US5672686A (en) * 1994-08-09 1997-09-30 Immunogen, Inc. Bcl-Y - specific antibodies

Also Published As

Publication number Publication date
US6433155B1 (en) 2002-08-13
JP2002516564A (ja) 2002-06-04
ATE318915T1 (de) 2006-03-15
US7045604B2 (en) 2006-05-16
DE69735375T2 (de) 2006-11-30
PT932678E (pt) 2006-07-31
US20040039184A1 (en) 2004-02-26
WO1998013493A2 (en) 1998-04-02
US7045596B2 (en) 2006-05-16
DK0932678T4 (da) 2010-07-12
CA2266325C (en) 2012-07-17
EP0932678B2 (de) 2010-03-10
ES2263181T5 (es) 2011-04-07
US20030023061A1 (en) 2003-01-30
WO1998013493A3 (en) 1998-06-04
EP0932678B1 (de) 2006-03-01
DE69735375T3 (de) 2010-09-02
DK0932678T3 (da) 2006-05-22
EP0932678A2 (de) 1999-08-04
JP4299886B2 (ja) 2009-07-22
AU737323B2 (en) 2001-08-16
ES2263181T3 (es) 2006-12-01
AU4651397A (en) 1998-04-17
CA2266325A1 (en) 1998-04-02
JP2009050257A (ja) 2009-03-12

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: GENTECH, INC., SAN FRANCISCO, CALIF., US