DE69727158D1 - Pharmazeutische zusammensetzungen enthaltend eine mischung von selbstvernetzter und nichtselbstvernetzter hyaluronsäure zur behandlung von arthropathien - Google Patents

Pharmazeutische zusammensetzungen enthaltend eine mischung von selbstvernetzter und nichtselbstvernetzter hyaluronsäure zur behandlung von arthropathien

Info

Publication number
DE69727158D1
DE69727158D1 DE69727158T DE69727158T DE69727158D1 DE 69727158 D1 DE69727158 D1 DE 69727158D1 DE 69727158 T DE69727158 T DE 69727158T DE 69727158 T DE69727158 T DE 69727158T DE 69727158 D1 DE69727158 D1 DE 69727158D1
Authority
DE
Germany
Prior art keywords
self
hyaluronic acid
linked
arthropathies
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69727158T
Other languages
English (en)
Other versions
DE69727158T2 (de
Inventor
Davide Belini
Annamaria Paparella
Michael O'regan
Lanfranco Callegaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Application granted granted Critical
Publication of DE69727158D1 publication Critical patent/DE69727158D1/de
Publication of DE69727158T2 publication Critical patent/DE69727158T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
DE69727158T 1996-06-21 1997-06-20 Pharmazeutische Zusammensetzung enthaltend eine Mischung von selbstvernetzter und nichtselbstvernetzter Hyaluronsäure zur Behandlung von Arthropathien Expired - Lifetime DE69727158T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96PD000163A IT1288290B1 (it) 1996-06-21 1996-06-21 Acido ialuronico autoreticolato e relative composizioni farmaceutiche per il trattamento delle artropatie
ITPD960163 1996-06-21
PCT/EP1997/003238 WO1997049412A1 (en) 1996-06-21 1997-06-20 Autocross-linked hyaluronic acid and related pharmaceutical compositions for the treatment of arthropathies

Publications (2)

Publication Number Publication Date
DE69727158D1 true DE69727158D1 (de) 2004-02-12
DE69727158T2 DE69727158T2 (de) 2004-11-11

Family

ID=11391464

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69727158T Expired - Lifetime DE69727158T2 (de) 1996-06-21 1997-06-20 Pharmazeutische Zusammensetzung enthaltend eine Mischung von selbstvernetzter und nichtselbstvernetzter Hyaluronsäure zur Behandlung von Arthropathien

Country Status (11)

Country Link
US (1) US6251876B1 (de)
EP (1) EP0954323B1 (de)
JP (1) JP2000512650A (de)
AT (1) ATE257386T1 (de)
AU (1) AU732979B2 (de)
CA (1) CA2258920C (de)
DE (1) DE69727158T2 (de)
ES (1) ES2214628T3 (de)
HK (1) HK1024865A1 (de)
IT (1) IT1288290B1 (de)
WO (1) WO1997049412A1 (de)

Families Citing this family (51)

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US6221854B1 (en) * 1996-03-05 2001-04-24 Orquest, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
IT1296689B1 (it) * 1997-11-06 1999-07-14 Fidia Advanced Biopolymers Srl Derivati esterei dell'acido ialuronico aventi proprieta viscoelastiche e loro uso in campo biomedico-sanitario
US6824793B1 (en) 1998-06-01 2004-11-30 Chiron Corporation Use of hyaluronic acid polymers for mucosal delivery of vaccine antigens and adjuvants
AU774977B2 (en) * 1998-11-10 2004-07-15 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel, process for the preparation thereof and medical materials containing the same
IT1302534B1 (it) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
JP2003089647A (ja) 1999-03-10 2003-03-28 Takada Seiyaku Kk 関節性疾患治療剤
EP1481695A1 (de) * 1999-10-15 2004-12-01 Genetics Institute, LLC Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
EP1223990B1 (de) * 1999-10-15 2004-07-28 Genetics Institute, LLC Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
EP1281722A4 (de) * 2000-02-03 2005-06-08 Denki Kagaku Kogyo Kk Hyaluronsäuregel, verfahren zu dessen herstellung sowie das gel enthaltendes medizinisches material
US6638312B2 (en) * 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
WO2003007784A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
AU2002316696B2 (en) 2001-07-16 2007-08-30 Depuy Products, Inc. Cartilage repair and regeneration scaffold and method
EP1416880B1 (de) * 2001-07-16 2011-03-02 DePuy Products, Inc. Gerät zur reparatur von knorpelmaterial
JP4197158B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 天然に発生する生物学的に誘導されている材料による装置
WO2003007786A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Porous delivery scaffold and method
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US7914808B2 (en) * 2001-07-16 2011-03-29 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
JPWO2003084571A1 (ja) * 2002-04-08 2005-08-11 電気化学工業株式会社 骨感染症治療用組成物
JP2005530768A (ja) * 2002-05-09 2005-10-13 メディジーンズ 血漿または血清を含有した創傷治療用医薬組成物
MXPA04011337A (es) 2002-05-17 2005-07-01 Wyeth Corp Portadores de acido hialuronico solidos y susceptibles de ser inyectados para la liberacion de proteinas osteogenicas.
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
CN100393322C (zh) * 2002-08-16 2008-06-11 电气化学工业株式会社 分离型医疗材料
US8138265B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8137688B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) * 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6982298B2 (en) * 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US20040185022A1 (en) * 2003-02-19 2004-09-23 Steven Rubin Regimen for acne treatment
US20040167480A1 (en) * 2003-02-21 2004-08-26 Advanced Medical Optics, Inc. Administration of multiple viscoelastic solutions with a multi-compartment syringe
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20120283232A9 (en) * 2003-11-12 2012-11-08 Zhengjun Wang Process for making a pharmaceutical composition
US20070224278A1 (en) * 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US8124120B2 (en) * 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
US8524213B2 (en) 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
US20050226936A1 (en) * 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US8017394B2 (en) * 2004-10-01 2011-09-13 Isto Technologies, Inc. Method for chondrocyte expansion with phenotype retention
US7273756B2 (en) 2004-10-01 2007-09-25 Isto Technologies, Inc. Method for chondrocyte expansion with phenotype retention
US7513866B2 (en) * 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7323184B2 (en) * 2005-08-22 2008-01-29 Healagenics, Inc. Compositions and methods for the treatment of wounds and the reduction of scar formation
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US9044477B2 (en) 2007-12-12 2015-06-02 Allergan, Inc. Botulinum toxin formulation
EP2249891B1 (de) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Molekulare verstärkung von extrazellulärer matrix und anwendungsverfahren
US8410180B2 (en) * 2008-04-30 2013-04-02 The Cleveland Clinic Foundation Methods to treat urinary incontinence
IT1395392B1 (it) 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
BR112015017246B1 (pt) 2013-01-23 2022-11-29 Semnur Pharmaceuticals, Inc Composição farmacêutica aquosa injetável, seu uso e seringa
TWI772659B (zh) 2015-01-21 2022-08-01 美商桑紐爾製藥公司 醫藥配方
IT201900021693A1 (it) * 2019-11-20 2021-05-20 Bmg Pharma S P A Derivati butirrati o butirrati e formiati dell’acido ialuronico reticolati e loro procedimento di reticolazione
EP4335876A1 (de) 2022-09-06 2024-03-13 Scivision Biotech Inc. Verfahren zur herstellung von selbstvernetztem hyaluronsäuregel und produkte daraus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses

Also Published As

Publication number Publication date
ES2214628T3 (es) 2004-09-16
CA2258920C (en) 2003-12-02
JP2000512650A (ja) 2000-09-26
AU3435497A (en) 1998-01-14
ITPD960163A1 (it) 1997-12-21
DE69727158T2 (de) 2004-11-11
EP0954323B1 (de) 2004-01-07
EP0954323A1 (de) 1999-11-10
US6251876B1 (en) 2001-06-26
ATE257386T1 (de) 2004-01-15
AU732979B2 (en) 2001-05-03
WO1997049412A1 (en) 1997-12-31
CA2258920A1 (en) 1997-12-31
HK1024865A1 (en) 2000-10-27
IT1288290B1 (it) 1998-09-11

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