DE69725442D1 - Medizinische geräte mit ionisch und nichtionisch vernetzten polymeren hydrogelen mit verbesserten mechanischen eigenschaften - Google Patents

Medizinische geräte mit ionisch und nichtionisch vernetzten polymeren hydrogelen mit verbesserten mechanischen eigenschaften

Info

Publication number
DE69725442D1
DE69725442D1 DE69725442T DE69725442T DE69725442D1 DE 69725442 D1 DE69725442 D1 DE 69725442D1 DE 69725442 T DE69725442 T DE 69725442T DE 69725442 T DE69725442 T DE 69725442T DE 69725442 D1 DE69725442 D1 DE 69725442D1
Authority
DE
Germany
Prior art keywords
ionic
mechanical properties
medical devices
crosslinked polymer
improved mechanical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69725442T
Other languages
English (en)
Other versions
DE69725442T2 (de
Inventor
John M Ronan
A Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Publication of DE69725442D1 publication Critical patent/DE69725442D1/de
Application granted granted Critical
Publication of DE69725442T2 publication Critical patent/DE69725442T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/008Implant devices for drainage of body fluids from one part of the body to another pre-shaped, for use in the urethral or ureteral tract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/145Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145Hydrogels or hydrocolloids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/24Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/243Two or more independent types of crosslinking for one or more polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00Characterised by the use of unspecified polymers
    • C08J2300/14Water soluble or water swellable polymers, e.g. aqueous gels
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S524/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S524/916Hydrogel compositions
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/903Interpenetrating network
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901Method of manufacturing prosthetic device
DE69725442T 1996-07-11 1997-06-30 Medizinische geräte mit ionisch und nichtionisch vernetzten polymeren hydrogelen mit verbesserten mechanischen eigenschaften Expired - Lifetime DE69725442T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US679609 1996-07-11
US08/679,609 US6060534A (en) 1996-07-11 1996-07-11 Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
PCT/US1997/013119 WO1998002204A1 (en) 1996-07-11 1997-06-30 Medical devices comprising ionically and non-ionically cross-linked polymer hydrogels having improved mechanical properties

Publications (2)

Publication Number Publication Date
DE69725442D1 true DE69725442D1 (de) 2003-11-13
DE69725442T2 DE69725442T2 (de) 2004-07-29

Family

ID=24727594

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69725442T Expired - Lifetime DE69725442T2 (de) 1996-07-11 1997-06-30 Medizinische geräte mit ionisch und nichtionisch vernetzten polymeren hydrogelen mit verbesserten mechanischen eigenschaften

Country Status (5)

Country Link
US (3) US6060534A (de)
EP (1) EP0912211B1 (de)
CA (1) CA2262523C (de)
DE (1) DE69725442T2 (de)
WO (1) WO1998002204A1 (de)

Families Citing this family (179)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6818018B1 (en) * 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US6211296B1 (en) * 1998-11-05 2001-04-03 The B. F. Goodrich Company Hydrogels containing substances
US6348042B1 (en) * 1999-02-02 2002-02-19 W. Lee Warren, Jr. Bioactive shunt
GB9902412D0 (en) 1999-02-03 1999-03-24 Fermentech Med Ltd Process
GB9902652D0 (en) 1999-02-05 1999-03-31 Fermentech Med Ltd Process
WO2000050103A1 (en) * 1999-02-25 2000-08-31 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
ES2491866T3 (es) * 1999-11-15 2014-09-08 Piramal Healthcare (Canada) Limited Disolución biopolimérica acuosa autogelificante controlada por la temperatura y dependiente del pH
DE60003459T2 (de) * 1999-12-09 2004-05-06 Biosyntech Canada Inc., Laval Mineral-polymer hybrid-zusammensetzung
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
US6355058B1 (en) * 1999-12-30 2002-03-12 Advanced Cardiovascular Systems, Inc. Stent with radiopaque coating consisting of particles in a binder
AU778318B2 (en) * 2000-02-03 2004-11-25 Tissuemed Limited Device for the closure of a surgical puncture
DE60115212T2 (de) * 2000-03-13 2006-07-27 Biocure, Inc. Biomedizinische artikel aus hydrogel
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
DE60130544T2 (de) 2000-03-13 2008-06-26 Biocure, Inc. Embolische zusammensetzungen
BR0112109A (pt) * 2000-06-29 2007-05-29 Biosyntech Canada Inc composição e método para a correção e regeneração de cartilagem e outros tecidos
DK1328300T3 (da) * 2000-10-23 2005-03-21 Tissuemed Ltd Selvklæbende hydratiserbar matrix til topisk terapeutisk anvendelse
AU2001297782B2 (en) 2000-11-07 2006-03-02 Cryolife, Inc. Expandable foam-like biomaterials and methods
CA2429168C (en) * 2000-11-15 2010-06-08 Bio Syntech Canada Inc. Method for restoring a damaged or degenerated intervertebral disc
US6664335B2 (en) 2000-11-30 2003-12-16 Cardiac Pacemakers, Inc. Polyurethane elastomer article with “shape memory” and medical devices therefrom
US6635082B1 (en) * 2000-12-29 2003-10-21 Advanced Cardiovascular Systems Inc. Radiopaque stent
US6685626B2 (en) 2001-02-02 2004-02-03 Regeneration Technologies, Inc. Compositions, devices, methods, and kits for induction of adhesions
US6913765B2 (en) * 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
EP1392182A1 (de) * 2001-05-04 2004-03-03 Concentric Medical Hydrogel-vorrichtung zum verschluss eines blutgefässes
WO2002089865A2 (en) * 2001-05-04 2002-11-14 Concentric Medical Coated combination vaso-occlusive device
WO2002089676A2 (en) * 2001-05-04 2002-11-14 Concentric Medical Hydrogel filament vaso-occlusive device
US7201940B1 (en) * 2001-06-12 2007-04-10 Advanced Cardiovascular Systems, Inc. Method and apparatus for thermal spray processing of medical devices
US7589070B2 (en) * 2001-06-15 2009-09-15 The Children's Hospital Of Philadelphia Surface modification for improving biocompatibility
US8252040B2 (en) * 2001-07-20 2012-08-28 Microvention, Inc. Aneurysm treatment device and method of use
US8715312B2 (en) * 2001-07-20 2014-05-06 Microvention, Inc. Aneurysm treatment device and method of use
US7572288B2 (en) * 2001-07-20 2009-08-11 Microvention, Inc. Aneurysm treatment device and method of use
US7562396B2 (en) * 2001-08-21 2009-07-14 Ecd Systems, Inc. Systems and methods for media authentication
US7097665B2 (en) 2003-01-16 2006-08-29 Synecor, Llc Positioning tools and methods for implanting medical devices
US20030073961A1 (en) * 2001-09-28 2003-04-17 Happ Dorrie M. Medical device containing light-protected therapeutic agent and a method for fabricating thereof
US20030093111A1 (en) * 2001-10-26 2003-05-15 Concentric Medical Device for vaso-occlusion and interventional therapy
US6783721B2 (en) * 2001-10-30 2004-08-31 Howmedica Osteonics Corp. Method of making an ion treated hydrogel
US20030100830A1 (en) * 2001-11-27 2003-05-29 Sheng-Ping Zhong Implantable or insertable medical devices visible under magnetic resonance imaging
US20040143180A1 (en) * 2001-11-27 2004-07-22 Sheng-Ping Zhong Medical devices visible under magnetic resonance imaging
US8133501B2 (en) 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
GB0210216D0 (en) * 2002-05-03 2002-06-12 First Water Ltd Ionically crosslinked alginate hydrogels, process for their manufacture and their use in medical devices
US20030215395A1 (en) * 2002-05-14 2003-11-20 Lei Yu Controllably degradable polymeric biomolecule or drug carrier and method of synthesizing said carrier
US7794743B2 (en) 2002-06-21 2010-09-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US7396539B1 (en) * 2002-06-21 2008-07-08 Advanced Cardiovascular Systems, Inc. Stent coatings with engineered drug release rate
US8506617B1 (en) 2002-06-21 2013-08-13 Advanced Cardiovascular Systems, Inc. Micronized peptide coated stent
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US7056523B1 (en) 2002-06-21 2006-06-06 Advanced Cardiovascular Systems, Inc. Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine
US7033602B1 (en) 2002-06-21 2006-04-25 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of coating implantable medical devices
US8920826B2 (en) * 2002-07-31 2014-12-30 Boston Scientific Scimed, Inc. Medical imaging reference devices
US7598224B2 (en) * 2002-08-20 2009-10-06 Biosurface Engineering Technologies, Inc. Dual chain synthetic heparin-binding growth factor analogs
US7981862B2 (en) * 2003-08-19 2011-07-19 Biosurface Engineering Technologies, Inc. Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis
US8227411B2 (en) * 2002-08-20 2012-07-24 BioSurface Engineering Technologies, Incle FGF growth factor analogs
US20040063805A1 (en) * 2002-09-19 2004-04-01 Pacetti Stephen D. Coatings for implantable medical devices and methods for fabrication thereof
DE60336158D1 (de) * 2002-10-11 2011-04-07 Univ Connecticut Auf semikristalline thermoplastische polyurethane die nanostrukturierte hartsegmente aufweisen basierenden formgedächtnispolymere
US7468210B1 (en) 2002-12-10 2008-12-23 Biosurface Engineering Technologies, Inc. Cross-linked heparin coatings and methods
US7094256B1 (en) * 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
US20040115164A1 (en) * 2002-12-17 2004-06-17 Pierce Ryan K. Soft filament occlusive device delivery system
EP1610752B1 (de) * 2003-01-31 2013-01-02 Boston Scientific Limited Lokalisierte arzneimittelabgabe unter verwendung von mit arzneimittel beladenen nanokapseln und damit beschichtete implantierbare vorrichtung
AU2004226578A1 (en) * 2003-04-04 2004-10-14 Tissuemed Limited Tissue-adhesive formulations
US7241455B2 (en) 2003-04-08 2007-07-10 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent
WO2004096127A2 (en) * 2003-04-25 2004-11-11 Kos Life Sciences, Inc. Formation of strong superporous hydrogels
US8791171B2 (en) * 2003-05-01 2014-07-29 Abbott Cardiovascular Systems Inc. Biodegradable coatings for implantable medical devices
US6923996B2 (en) * 2003-05-06 2005-08-02 Scimed Life Systems, Inc. Processes for producing polymer coatings for release of therapeutic agent
US7364585B2 (en) * 2003-08-11 2008-04-29 Boston Scientific Scimed, Inc. Medical devices comprising drug-loaded capsules for localized drug delivery
US20050074406A1 (en) * 2003-10-03 2005-04-07 Scimed Life Systems, Inc. Ultrasound coating for enhancing visualization of medical device in ultrasound images
US20050107867A1 (en) * 2003-11-17 2005-05-19 Taheri Syde A. Temporary absorbable venous occlusive stent and superficial vein treatment method
ZA200604869B (en) 2003-12-04 2007-11-28 Univ Utah Res Found Modified macromolecules and methods of making and using thereof
US7910124B2 (en) 2004-02-06 2011-03-22 Georgia Tech Research Corporation Load bearing biocompatible device
WO2005077013A2 (en) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Surface directed cellular attachment
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
ATE482228T1 (de) * 2004-02-20 2010-10-15 Biosurface Eng Tech Inc Positiver modulator des knochenmorphogenetisches protein-2 (bmp-2)
US8426528B2 (en) * 2004-02-23 2013-04-23 E I Du Pont De Nemours And Company Preparation of crosslinked polymers containing biomass derived materials
US20050220882A1 (en) * 2004-03-04 2005-10-06 Wilson Pritchard Materials for medical implants and occlusive devices
US8067073B2 (en) 2004-03-25 2011-11-29 Boston Scientific Scimed, Inc. Thermoplastic medical device
US7282165B2 (en) * 2004-04-27 2007-10-16 Howmedica Osteonics Corp. Wear resistant hydrogel for bearing applications
EP1595534A1 (de) * 2004-05-13 2005-11-16 Universiteit Utrecht Holding B.V. Gelzusammensetzung enthaltend geladenepolymere
ES2609105T3 (es) 2004-05-20 2017-04-18 Mentor Worldwide Llc Método de enlance covalente de ácido hialurónico y quitosano
EP1750769B1 (de) * 2004-05-20 2013-01-23 Mentor Worldwide LLC Verfahren zur herstellung eines injizierbaren polymerhydrogels
CA2572603C (en) * 2004-06-29 2013-01-15 Biocure, Inc. Spinal disc nucleus pulposus implant
EP1793873B1 (de) * 2004-08-03 2013-08-07 Tissuemed Limited Gewebekleber
US20060052822A1 (en) * 2004-08-31 2006-03-09 Mirizzi Michael S Apparatus and material composition for permanent occlusion of a hollow anatomical structure
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
DE102004045224B4 (de) * 2004-09-17 2010-12-30 Thilo Dr. Fliedner Stützprothese
US20060074182A1 (en) * 2004-09-30 2006-04-06 Depuy Products, Inc. Hydrogel composition and methods for making the same
US7972354B2 (en) * 2005-01-25 2011-07-05 Tyco Healthcare Group Lp Method and apparatus for impeding migration of an implanted occlusive structure
US20060222596A1 (en) 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
KR100748348B1 (ko) 2005-07-19 2007-08-09 한국원자력연구원 방사선 조사기술을 이용한 상처 치료용 수화겔의 제조방법
US9101436B2 (en) * 2005-10-21 2015-08-11 Ada Foundation Dental and endodontic filling materials and methods
US9259439B2 (en) * 2005-10-21 2016-02-16 Ada Foundation Dual-phase cement precursor systems for bone repair
US8048350B2 (en) * 2005-10-31 2011-11-01 Scott Epstein Structural hydrogel polymer device
US11896505B2 (en) 2005-10-31 2024-02-13 Scott M. Epstein Methods for making and using a structural hydrogel polymer device
CA2628313A1 (en) * 2005-11-04 2007-05-31 Bio Syntech Canada Inc. Composition and method for efficient delivery of nucleic acids to cells using chitosan
US20070149641A1 (en) * 2005-12-28 2007-06-28 Goupil Dennis W Injectable bone cement
US9393344B2 (en) * 2006-01-11 2016-07-19 Hyperbranch Medical Technology, Inc. Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices
CA2640629A1 (en) 2006-02-03 2007-08-09 Tissuemed Limited Tissue-adhesive materials
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
FR2897775B1 (fr) * 2006-02-24 2013-05-03 Elisabeth Laugier Biomateriau, implant injectable le comprenant, son procede de preparation et ses utilisations
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
US9017361B2 (en) 2006-04-20 2015-04-28 Covidien Lp Occlusive implant and methods for hollow anatomical structure
US7820172B1 (en) 2006-06-01 2010-10-26 Biosurface Engineering Technologies, Inc. Laminin-derived multi-domain peptides
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
CN101557801B (zh) * 2006-07-14 2013-10-30 Fmc生物聚合物联合股份有限公司 含有低分子量藻酸盐的水凝胶和从其制备的生物构建物
US9585989B2 (en) * 2006-09-19 2017-03-07 Boston Scientific Scimed, Inc. Ureteral stent having variable hardness
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
US20080132991A1 (en) * 2006-11-30 2008-06-05 Leonard Pinchuk Method for Ionically Cross-Linking Gellan Gum for Thin Film Applications and Medical Devices Produced Therefrom
ATE532089T1 (de) * 2007-02-09 2011-11-15 Novartis Ag Vernetzbare polyionische beschichtungen für kontaktlinsen
US20080234659A1 (en) * 2007-03-20 2008-09-25 Boston Scientific Scimed, Inc. Urological medical devices for release of therapeutic agents
CA2687281A1 (en) * 2007-03-20 2008-09-25 Boston Scientific Limited Urological medical devices for release of prostatically beneficial therapeutic agents
JP2010526914A (ja) * 2007-05-11 2010-08-05 エアリス セラピューティクス エルエルシー 架橋した非天然ポリマーを用いる肺容量減少療法
WO2009003049A2 (en) 2007-06-25 2008-12-31 Micro Vention, Inc. Self-expanding prosthesis
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
WO2009022358A1 (en) * 2007-08-10 2009-02-19 Luigi Ambrosio Superabsorbent polymer hydro gels and a method of preparing thereof
US8066755B2 (en) 2007-09-26 2011-11-29 Trivascular, Inc. System and method of pivoted stent deployment
US8226701B2 (en) 2007-09-26 2012-07-24 Trivascular, Inc. Stent and delivery system for deployment thereof
US8663309B2 (en) 2007-09-26 2014-03-04 Trivascular, Inc. Asymmetric stent apparatus and method
CN101917929A (zh) 2007-10-04 2010-12-15 特里瓦斯库拉尔公司 用于低型面经皮递送的模块化脉管移植物
US7919542B2 (en) * 2007-11-12 2011-04-05 Zimmer Spine, Inc. Phase separated, branched, copolymer hydrogel
US8328861B2 (en) 2007-11-16 2012-12-11 Trivascular, Inc. Delivery system and method for bifurcated graft
US8083789B2 (en) 2007-11-16 2011-12-27 Trivascular, Inc. Securement assembly and method for expandable endovascular device
WO2009108760A2 (en) 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US20090220578A1 (en) * 2008-02-28 2009-09-03 Depuy Products, Inc. Hydrogel composition and method for making the same
US7932176B2 (en) 2008-03-21 2011-04-26 President And Fellows Of Harvard College Self-aligned barrier layers for interconnects
CN102016596B (zh) 2008-03-27 2014-09-17 哈佛学院院长等 纸基微流体系统
WO2009121038A2 (en) * 2008-03-27 2009-10-01 President And Fellows Of Harvard College Shaped films of hydrogels fabricated using templates of patterned paper
EP2265959B1 (de) * 2008-03-27 2014-03-05 President and Fellows of Harvard College Zelluläre arrays auf papierbasis
CN102016594B (zh) * 2008-03-27 2014-04-23 哈佛学院院长等 用作低成本多重分析诊断平台的棉线
EP2257819A4 (de) 2008-03-27 2017-10-11 President and Fellows of Harvard College Dreidimensionale mikrofluidische vorrichtungen
MY144571A (en) * 2008-04-24 2011-10-14 Univ Malaya Extracellular scaffold
US7959762B2 (en) * 2008-06-30 2011-06-14 Weyerhaeuser Nr Company Method for making biodegradable superabsorbent particles
US8641869B2 (en) * 2008-06-30 2014-02-04 Weyerhaeuser Nr Company Method for making biodegradable superabsorbent particles
US7833384B2 (en) * 2008-06-30 2010-11-16 Weyerhaeuser Nr Company Method for making fiber having biodegradable superabsorbent particles attached thereto
US8101543B2 (en) * 2008-06-30 2012-01-24 Weyerhaeuser Nr Company Biodegradable superabsorbent particles
US20090325797A1 (en) * 2008-06-30 2009-12-31 Weyerhaeuser Co. Biodegradable Superabsorbent Particles
US20090326180A1 (en) * 2008-06-30 2009-12-31 Weyerhaeuser Co. Biodegradable Superabsorbent Particles Containing Cellulose Fiber
US8084391B2 (en) * 2008-06-30 2011-12-27 Weyerhaeuser Nr Company Fibers having biodegradable superabsorbent particles attached thereto
DE102008053892A1 (de) 2008-10-30 2010-05-06 Fachhochschule Gelsenkirchen Medizinisches Implantat mit biofunktionalisierter Oberfläche
US9192933B2 (en) 2009-03-06 2015-11-24 President And Fellows Of Harvard College Microfluidic, electrochemical devices
SG10201503679UA (en) 2009-10-23 2015-06-29 Harvard College Self-aligned barrier and capping layers for interconnects
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
WO2011057131A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Polysaccharide based hydrogels
US9370626B2 (en) * 2009-11-24 2016-06-21 University Of Florida Research Foundation, Inc. Apparatus and methods for blocking needle and cannula tracts
JP5820815B2 (ja) 2009-12-15 2015-11-24 インセプト・リミテッド・ライアビリティ・カンパニーIncept,Llc インプラントおよび生体分解性基準マーカー
CA2788113A1 (en) 2010-02-03 2011-08-11 President And Fellows Of Harvard College Devices and methods for multiplexed assays
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
WO2012001707A1 (en) 2010-07-02 2012-01-05 Indian Council Of Agricultural Research Novel superabsorbents and the method(s) of obtaining the same
US8946194B2 (en) 2010-10-08 2015-02-03 Board Of Regents, University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
EP2643020A4 (de) * 2010-11-26 2014-11-12 Univ Witwatersrand Jhb Wirkstofffreisetzungsvorrichtung
KR101303284B1 (ko) 2011-04-06 2013-09-04 한국원자력연구원 히알루론산과 콘드로이틴 설페이트를 함유한 수화겔 및 이의 제조방법
JP2014522263A (ja) 2011-05-11 2014-09-04 マイクロベンション インコーポレイテッド 内腔を閉塞するためのデバイス
EP2757964B1 (de) 2011-05-26 2016-05-04 Cartiva, Inc. Konisches gelenkimplantat und zugehörige instrumente
AU2012267855B2 (en) 2011-06-07 2016-03-03 Gelesis Llc Method for producing hydrogels
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy
US8968926B2 (en) 2011-07-15 2015-03-03 Covidien Lp Degradable implantable galvanic power source
US8968927B2 (en) 2011-07-15 2015-03-03 Covidien Lp Degradable implantable battery
AU2012347926B2 (en) 2011-12-05 2018-03-15 Incept, Llc Medical organogel processes and compositions
US8992595B2 (en) 2012-04-04 2015-03-31 Trivascular, Inc. Durable stent graft with tapered struts and stable delivery methods and devices
US9498363B2 (en) 2012-04-06 2016-11-22 Trivascular, Inc. Delivery catheter for endovascular device
CZ2012282A3 (cs) 2012-04-25 2013-11-06 Contipro Biotech S.R.O. Zesítovaný derivát hyaluronanu, zpusob jeho prípravy, hydrogel a mikrovlákna na jeho bázi
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
EP3505197B1 (de) 2012-12-11 2023-09-06 Board of Regents, The University of Texas System Hydrogelmembran zur anhaftungsverhinderung
WO2014144364A1 (en) 2013-03-15 2014-09-18 Children's Medical Center Corporation Gas-filled stabilized particles and methods of use
CN103446897B (zh) * 2013-09-13 2015-03-11 天津工业大学 一种过滤用化学和离子交联海藻酸盐水凝胶平板膜及其制备方法
AU2014240353A1 (en) * 2013-11-12 2015-05-28 Covidien Lp Degradable implantable battery
US10420859B2 (en) * 2013-12-12 2019-09-24 Hollister Incorporated Flushable catheters
MX2017009805A (es) 2015-01-29 2018-05-07 Gelesis Llc Método para la producción de hidrogeles que juntan alto módulo elástico y absorbancia.
CA2981061A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
EP3892241A1 (de) 2015-03-31 2021-10-13 Cartiva, Inc. Bohrer für karpometakarpalimplantat
CA2981074C (en) 2015-04-14 2023-03-28 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
US10471183B2 (en) 2015-12-22 2019-11-12 Access Vascular, Inc. High strength biomedical materials
KR101624511B1 (ko) 2016-01-15 2016-05-26 전남대학교산학협력단 유착방지 조성물 및 이를 포함하는 유착방지제 제조방법
CN105797685A (zh) * 2016-05-09 2016-07-27 江苏大学 一种海藻酸钠-氧化石墨烯宏观球体复合材料的制备方法
WO2018024793A1 (en) 2016-08-03 2018-02-08 Galderma Research & Development Method of crosslinking glycosaminoglycans
EP3494146A1 (de) 2016-12-23 2019-06-12 Galderma Research & Development Doppelt vernetzte glykosaminoglykane
US11577008B2 (en) 2017-06-21 2023-02-14 Access Vascular, Inc. High strength porous materials incorporating water soluble polymers
US20200254144A1 (en) * 2019-02-08 2020-08-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Composite gels and methods of use thereof
WO2020227705A1 (en) * 2019-05-09 2020-11-12 Soliman Sherif Hydrogel retinal tamponade agent
CN114015074B (zh) * 2021-10-20 2023-09-12 武汉理工大学 一种羧甲基壳聚糖/聚丙烯酰胺可注射自愈水凝胶及其制备方法和应用
US11911572B2 (en) 2022-05-05 2024-02-27 Innocare Urologics, Llc Soft tip drug-eluting urinary drainage catheter

Family Cites Families (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2485512A (en) 1941-10-21 1949-10-18 Alginate Ind Ltd Manufacture of transparent alginic films
GB674755A (en) 1949-08-04 1952-07-02 Courtaulds Ltd Improvements in and relating to the production of artificial protein fibres
US2689809A (en) 1951-10-08 1954-09-21 Permachem Corp Self-sterilizing article and its preparation
US2712672A (en) 1952-01-28 1955-07-12 Calcagno Luigi Process for preparing proteic sponges
US2791518A (en) 1955-03-21 1957-05-07 Permachem Corp Process for making a microbicidal article
US2847713A (en) 1955-05-13 1958-08-19 Weingand Richard Process for producing synthetic sausage skins and other laminar structures from alginates
US2897547A (en) 1955-05-27 1959-08-04 Weingand Richard Process for producing synthetic sausage casing from alginates or alginic acid
US3271496A (en) 1964-01-27 1966-09-06 Amicon Corp Method of shaping polyelectrolyte polymer
US3975350A (en) 1972-08-02 1976-08-17 Princeton Polymer Laboratories, Incorporated Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles
US4137921A (en) 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
SE425372B (sv) 1977-07-18 1982-09-27 Ird Biomaterial Ab Sett att heparinisera en elektriskt laddad yta pa en medecinsk artikel avsedd att komma i kontakt med blod och medel for utforande av settet
DE2824893C2 (de) 1978-06-07 1980-04-24 Willy Ruesch Gmbh & Co Kg, 7053 Kernen Sonde zur enteralen Behandlung
US4339295A (en) 1978-12-20 1982-07-13 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Hydrogel adhesives and sandwiches or laminates using microwave energy
US4286341A (en) * 1979-04-16 1981-09-01 Iowa State University Research Foundation, Inc. Vascular prosthesis and method of making the same
FR2484246A1 (fr) 1980-06-17 1981-12-18 Europ Propulsion Procede pour la realisation de revetements bioactifs sur des protheses osseuses, et protheses ainsi obtenues
JPS5714640A (en) 1980-07-02 1982-01-25 Toray Ind Inc Separating membrane of methyl methacrylate type
EP0065884B1 (de) 1981-05-27 1986-08-20 Unitika Ltd. Zur Verhinderung einer Harnleiterinfektion geeigneter Urethralkatheter und Verfahren zur Herstellung desselben
US4499154A (en) 1982-09-03 1985-02-12 Howard L. Podell Dipped rubber article
US4700704A (en) 1982-10-01 1987-10-20 Ethicon, Inc. Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same
US4613517A (en) 1983-04-27 1986-09-23 Becton, Dickinson And Company Heparinization of plasma treated surfaces
US4527293A (en) 1983-05-18 1985-07-09 University Of Miami Hydrogel surface of urological prosthesis
US4592920A (en) 1983-05-20 1986-06-03 Baxter Travenol Laboratories, Inc. Method for the production of an antimicrobial catheter
GB8318403D0 (en) 1983-07-07 1983-08-10 Sutherland I W Gel-forming polysaccharides
CA1238043A (en) 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
FR2559666B1 (fr) 1984-02-21 1986-08-08 Tech Cuir Centre Procede de fabrication de tubes de collagene, notamment de tubes de faibles diametres, et application des tubes obtenus dans le domaine des protheses vasculaires et des sutures nerveuses
US4716224A (en) 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
US4650488A (en) 1984-05-16 1987-03-17 Richards Medical Company Biodegradable prosthetic device
US4886870A (en) 1984-05-21 1989-12-12 Massachusetts Institute Of Technology Bioerodible articles useful as implants and prostheses having predictable degradation rates
SE442820B (sv) 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
US4863907A (en) 1984-06-29 1989-09-05 Seikagaku Kogyo Co., Ltd. Crosslinked glycosaminoglycans and their use
JPS6129720U (ja) 1984-07-28 1986-02-22 高砂医科工業株式会社 腸管吻合補助具
US4801475A (en) 1984-08-23 1989-01-31 Gregory Halpern Method of hydrophilic coating of plastics
US4674506A (en) 1984-11-29 1987-06-23 Kirk Alcond Surgical anastomosis stent
US4605691A (en) 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4636524A (en) 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US5128326A (en) 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US4871365A (en) 1985-04-25 1989-10-03 American Cyanamid Company Partially absorbable prosthetic tubular article having an external support
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
US5202431A (en) 1985-07-08 1993-04-13 Fidia, S.P.A. Partial esters of hyaluronic acid
JPS6227169A (ja) 1985-07-29 1987-02-05 Oki Electric Ind Co Ltd シリアルプリンタの印字位置決め方式
AU589438B2 (en) 1985-08-26 1989-10-12 Hana Biologics, Inc. Transplantable artificial tissue and process
US4902295A (en) 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
US4997443A (en) 1985-08-26 1991-03-05 Hana Biologics, Inc. Transplantable artificial tissue and process
SE8504501D0 (sv) 1985-09-30 1985-09-30 Astra Meditec Ab Method of forming an improved hydrophilic coating on a polymer surface
US5298569A (en) 1985-10-30 1994-03-29 Nippon Paint Co. Metallic ester acrylic compositions capable of releasing bioactive substance at a controlled rate
US4838876A (en) 1986-04-29 1989-06-13 The Kendall Company Silicone rubber catheter having improved surface morphology
FI81010C (fi) 1986-09-05 1990-09-10 Biocon Oy Stoedstruktur foer bentransplantat.
ES2040719T3 (es) 1986-09-23 1993-11-01 American Cyanamid Company Recubrimiento bioabsorbible para un articulo quirurgico.
IT1198449B (it) 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
JPH0696023B2 (ja) * 1986-11-10 1994-11-30 宇部日東化成株式会社 人工血管およびその製造方法
GB8630363D0 (en) 1986-12-19 1987-01-28 Igel Int Ltd Coloured hydrogel objects
JPS6425870A (en) 1987-04-30 1989-01-27 Ajinomoto Kk Support for anastomosis or bonding of living body
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
US5527337A (en) 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
US5059211A (en) 1987-06-25 1991-10-22 Duke University Absorbable vascular stent
US4923645A (en) 1987-11-16 1990-05-08 Damon Biotech, Inc. Sustained release of encapsulated molecules
US4916193A (en) * 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US4958038A (en) 1987-12-21 1990-09-18 E. I. Du Pont De Nemours And Company Organotitanium compositions useful for cross-linking
JP2561853B2 (ja) 1988-01-28 1996-12-11 株式会社ジェイ・エム・エス 形状記憶性を有する成形体及びその使用方法
US5147399A (en) 1988-02-01 1992-09-15 Dellon Arnold L Method of treating nerve defects through use of a bioabsorbable surgical device
US4888016A (en) 1988-02-10 1989-12-19 Langerman David W "Spare parts" for use in ophthalmic surgical procedures
US5061738A (en) 1988-04-18 1991-10-29 Becton, Dickinson And Company Blood compatible, lubricious article and composition and method therefor
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US4874360A (en) 1988-07-01 1989-10-17 Medical Engineering Corporation Ureteral stent system
US5444113A (en) 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
US5502158A (en) 1988-08-08 1996-03-26 Ecopol, Llc Degradable polymer composition
DE68922497T2 (de) 1988-08-24 1995-09-14 Marvin J Slepian Endoluminale dichtung mit bisdegradierbaren polymeren.
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5085629A (en) * 1988-10-06 1992-02-04 Medical Engineering Corporation Biodegradable stent
FI85223C (fi) 1988-11-10 1992-03-25 Biocon Oy Biodegraderande kirurgiska implant och medel.
US4948575A (en) 1989-01-24 1990-08-14 Minnesota Mining And Manufacturing Company Alginate hydrogel foam wound dressing
US5089606A (en) 1989-01-24 1992-02-18 Minnesota Mining And Manufacturing Company Water-insoluble polysaccharide hydrogel foam for medical applications
US5057606A (en) 1989-01-24 1991-10-15 Minnesota Mining And Manufacturing Company Form-in-place polysaccharide gels
US5554388A (en) 1989-02-25 1996-09-10 Danbiosyst Uk Limited Systemic drug delivery compositions comprising a polycationi substance
US5425739A (en) 1989-03-09 1995-06-20 Avatar Design And Development, Inc. Anastomosis stent and stent selection system
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5141516A (en) 1989-07-26 1992-08-25 Detweiler Mark B Dissolvable anastomosis stent and method for using the same
US5049138A (en) 1989-11-13 1991-09-17 Boston Scientific Corporation Catheter with dissolvable tip
US4994074A (en) 1990-02-01 1991-02-19 Ethicon, Inc. Copolymers of ε-caprolactone, glycolide and glycolic acid for suture coatings
DK0441516T3 (da) 1990-02-08 1995-06-12 Howmedica Oppusteligt kateter
US5178234A (en) 1990-03-15 1993-01-12 Tokyo Electric Co., Ltd. Checkout apparatus
DE69112260T2 (de) 1990-04-23 1996-04-11 Monsanto Co Gellan-Gummi-Fasern.
US5077352A (en) 1990-04-23 1991-12-31 C. R. Bard, Inc. Flexible lubricious organic coatings
NO171069C (no) 1990-05-29 1993-01-20 Protan Biopolymer As Kovalent tverrbundne, sterkt svellende alkalimetall- og ammonium-alginatgeler, samt fremgangsmaate for fremstilling derav
IT1248666B (it) 1990-05-30 1995-01-26 Fidia Spa Gel in forma di film autosupportanti altamente idrati, processo per laloro preparazione e impiego nella terapia di lesioni e/o patologie cutanee
US5077033A (en) * 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US5149543A (en) 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
JP2777279B2 (ja) 1990-10-08 1998-07-16 工業技術院長 創傷被覆材及びその製造方法
US5160341A (en) 1990-11-08 1992-11-03 Advanced Surgical Intervention, Inc. Resorbable urethral stent and apparatus for its insertion
US5162110A (en) 1990-12-19 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Binding theophylline to ion exchange resins
GR920100122A (el) * 1991-04-05 1993-03-16 Ethicon Inc Πολυσακχαρίτες οι οποίοι περιέχουν καρβοξύλιο με σταυροειδείς δεσμούς δια την πρόληψιν της προσφύσεως.
EP0580803B1 (de) 1991-04-10 1999-07-07 CAPELLI, Christopher C. Antimikrobielle zusammensetzungen für medizinische anwendungen
US5662913A (en) 1991-04-10 1997-09-02 Capelli; Christopher C. Antimicrobial compositions useful for medical applications
US5302393A (en) 1991-07-11 1994-04-12 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor
JPH07503943A (ja) * 1991-10-29 1995-04-27 クローバー コンソリデイテッド,リミテッド 封入及び薬剤放出に有用な架橋性の多糖類、ポリカチオン及び脂質
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
EP0625070B1 (de) * 1991-12-20 1998-07-08 AlliedSignal Inc. Materialien mit niedriger dichte und hoher spezifischer oberflaeche und daraus geformte artikel zur verwendung in der metallrueckgewinnung
US5489297A (en) 1992-01-27 1996-02-06 Duran; Carlos M. G. Bioprosthetic heart valve with absorbable stent
US5334640A (en) * 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
DE69320470T2 (de) * 1992-04-24 1999-04-29 Polymer Technology Group Inc Copolymere, sowie daraus hergestellte nichtporöse halbdurchlässige membranen und ihre verwendung zum filtern von molekülen in einem vorgegebenen molekulargewichtbereich
US5306764A (en) 1992-09-03 1994-04-26 China Technical Consultants Inc. Water dispersible polyurethane and process for preparation thereof
US5292525A (en) 1992-10-14 1994-03-08 Merck & Co., Inc. Method and composition for removing an alginate from a cutaneous substrate
US5443458A (en) 1992-12-22 1995-08-22 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method of manufacture
US5328939A (en) * 1993-04-27 1994-07-12 Alliedsignal Inc. Rigid materials having high surface area and low density
US5401257A (en) 1993-04-27 1995-03-28 Boston Scientific Corporation Ureteral stents, drainage tubes and the like
EP0701587B1 (de) * 1993-05-03 1997-08-06 Stockhausen GmbH & Co. KG Polymerzusammensetzungen, herstellung von polymerzusammensetzungen, insbesondere absorptionsmaterialien und deren verwendung
US5425949A (en) 1993-06-11 1995-06-20 United States Surgical Corporation Bioabsorbable copolymer and coating composition containing same
CA2123647C (en) 1993-06-11 2007-04-17 Steven L. Bennett Bioabsorbable copolymer and coating composition containing same
JPH0733682A (ja) 1993-07-26 1995-02-03 Shiseido Co Ltd 新規複合体、それを担体として利用する徐放性製剤
US5531716A (en) * 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US5514377A (en) 1994-03-08 1996-05-07 The Regents Of The University Of California In situ dissolution of alginate coatings of biological tissue transplants
US5541304A (en) * 1994-05-02 1996-07-30 Hercules Incorporated Crosslinked hydrogel compositions with improved mechanical performance
US5629077A (en) 1994-06-27 1997-05-13 Advanced Cardiovascular Systems, Inc. Biodegradable mesh and film stent
US5603955A (en) 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
US5578662A (en) 1994-07-22 1996-11-26 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US5527324A (en) 1994-09-07 1996-06-18 Krantz; Kermit E. Surgical stent
US5531735A (en) * 1994-09-27 1996-07-02 Hercules Incorporated Medical devices containing triggerable disintegration agents
US5690961A (en) 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
EP0810845A2 (de) 1995-02-22 1997-12-10 Menlo Care Inc. Expandierbarer netzstent mit einer umhüllung
US5713852A (en) * 1995-06-07 1998-02-03 Alza Corporation Oral dosage and method for treating painful conditions of the oral cavity
US5702682A (en) 1995-12-01 1997-12-30 Hercules Incorporated Methods for preparing radiopaque medical devices
US5684051A (en) * 1996-04-24 1997-11-04 Hercules Incorporated Medical devices with improved elastic response
US5670161A (en) 1996-05-28 1997-09-23 Healy; Kevin E. Biodegradable stent
US5820918A (en) 1996-07-11 1998-10-13 Hercules Incorporated Medical devices containing in-situ generated medical compounds
US5830217A (en) 1996-08-09 1998-11-03 Thomas J. Fogarty Soluble fixation device and method for stent delivery catheters
US5718916A (en) 1997-02-03 1998-02-17 Scherr; George H. Alginate foam products

Also Published As

Publication number Publication date
CA2262523C (en) 2005-09-20
WO1998002204A1 (en) 1998-01-22
US6060534A (en) 2000-05-09
EP0912211A1 (de) 1999-05-06
US20010002411A1 (en) 2001-05-31
US6184266B1 (en) 2001-02-06
EP0912211B1 (de) 2003-10-08
DE69725442T2 (de) 2004-07-29
CA2262523A1 (en) 1998-01-22
US6387978B2 (en) 2002-05-14
EP0912211A4 (de) 2000-08-16

Similar Documents

Publication Publication Date Title
DE69725442D1 (de) Medizinische geräte mit ionisch und nichtionisch vernetzten polymeren hydrogelen mit verbesserten mechanischen eigenschaften
DE69722890D1 (de) Polyethercopolymer und fester Polymerelektrolyt
DE69425900D1 (de) Verzweigtes ethylen makromonomer und daraus hergestelltes polymer
AU4172389A (en) Crosslinked siloxane-urethane polymer contact lens
DE69908803D1 (de) Verbundelektrode mit ptc polymer
DE69734339D1 (de) Ionenleitender gelierter Polymerelektrolyt und diesen Elektrolyt enthaltende Feststoffbatterie
DE69821218D1 (de) Modifizierte ionomere mit verbesserten eigenschaften und verarbeitbarkeit
DE59706518D1 (de) Polymere mit antimikrobiellen eigenschaften
DE69710629D1 (de) Stabilisierung von Polymeren mit Siloxan-Endgruppen
DE69836501D1 (de) Polymerisationsverfahren mit lebenden eigenschaften und daraus hergestellte polymere
DE69804341D1 (de) Wässrige polyurethane und daraus hergestellte filme mit elastischen eigenschaften
DE69723710D1 (de) Medizinische instrumente mit verbesserter elastizität
DE69731806D1 (de) Optisches element mit zirkularem dichroismus, vorrichtung dafür und flüssigkristallpolymer
DE69232172D1 (de) Ionisch leitende polymergele
DE69527828D1 (de) Optisches Tiefpass-Filter aus Polymermaterial und Vorrichtung damit
DE69513131D1 (de) Luftreifen mit elektrisch ableitenden Eigenschaften
DE69711327D1 (de) Gerät mit dielektrischem Resonator und Hochfrequenzmodul
DE69705629D1 (de) Medizinische elektrische leitung und hierbei verwendete verstärkte siliconelastomerzusammensetzung
DE69724765D1 (de) Schmutzabweisende mischungen aus polymeren mit carboxylgruppen und resol-harzen
DE69410250T2 (de) Polymeren mit nichtlinear optische eigenschaften
DK0994732T3 (da) Absorberende struktur omfattende en stærkt absorberende polymer og en absorberende artikel omfattende den absorberende struktur
DE69700997D1 (de) Mikrozellulare elastomere mit verbesserter verarbeitbarkeit und verbesserten eigenschaften
ID18732A (id) Penggunaan polimer dispersi hidrofilik pada perlakuan kertas rusak terlapis
DE69722904D1 (de) Nicht-wassrige Polymer Dispersion und hartbare Zusammensetzung
DE60019982D1 (de) Ionenleitfähiges Polymer, Polymerelektrolyt und elektrisches Gerät

Legal Events

Date Code Title Description
8364 No opposition during term of opposition