DE69720505D1 - Verfahren und vorrichtung zur identifizierung und charakterisierung von biomolekuelen - Google Patents
Verfahren und vorrichtung zur identifizierung und charakterisierung von biomolekuelenInfo
- Publication number
- DE69720505D1 DE69720505D1 DE69720505T DE69720505T DE69720505D1 DE 69720505 D1 DE69720505 D1 DE 69720505D1 DE 69720505 T DE69720505 T DE 69720505T DE 69720505 T DE69720505 T DE 69720505T DE 69720505 D1 DE69720505 D1 DE 69720505D1
- Authority
- DE
- Germany
- Prior art keywords
- biomolecules
- computer
- dimensional array
- gel
- solid support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44739—Collecting the separated zones, e.g. blotting to a membrane or punching of gel spots
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00644—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being present in discrete locations, e.g. gel pads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00691—Automatic using robots
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
- G01N2001/288—Filter punches
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9624927.1A GB9624927D0 (en) | 1996-11-29 | 1996-11-29 | Gels and their use |
GB9624927 | 1996-11-29 | ||
PCT/GB1997/003307 WO1998023950A1 (en) | 1996-11-29 | 1997-12-01 | Gels, methods and apparatus for identification and characterization of biomolecules |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69720505D1 true DE69720505D1 (de) | 2003-05-08 |
DE69720505T2 DE69720505T2 (de) | 2004-03-04 |
Family
ID=10803727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69720505T Expired - Fee Related DE69720505T2 (de) | 1996-11-29 | 1997-12-01 | Verfahren und vorrichtung zur identifizierung und charakterisierung von biomolekuelen |
Country Status (13)
Country | Link |
---|---|
US (4) | US6064754A (de) |
EP (2) | EP1302768A3 (de) |
JP (1) | JP3462220B2 (de) |
CN (1) | CN1125981C (de) |
AT (1) | ATE236392T1 (de) |
AU (1) | AU713259B2 (de) |
CA (1) | CA2272092C (de) |
DE (1) | DE69720505T2 (de) |
DK (1) | DK0941477T3 (de) |
GB (1) | GB9624927D0 (de) |
NO (1) | NO992583L (de) |
WO (1) | WO1998023950A1 (de) |
ZA (1) | ZA9710792B (de) |
Families Citing this family (190)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6027711A (en) * | 1995-06-07 | 2000-02-22 | Rhomed Incorporated | Structurally determined metallo-constructs and applications |
GB9624927D0 (en) * | 1996-11-29 | 1997-01-15 | Oxford Glycosciences Uk Ltd | Gels and their use |
AUPO625497A0 (en) | 1997-04-16 | 1997-05-15 | Macquarie Research Limited | Analysis of molecules |
US6554991B1 (en) * | 1997-06-24 | 2003-04-29 | Large Scale Proteomics Corporation | Automated system for two-dimensional electrophoresis |
US5993627A (en) | 1997-06-24 | 1999-11-30 | Large Scale Biology Corporation | Automated system for two-dimensional electrophoresis |
WO1999015875A1 (en) * | 1997-09-25 | 1999-04-01 | Macquarie Research Ltd. | Apparatus for removing a sample from an array of samples and a cutting tool for use with that apparatus |
EP1017982A4 (de) * | 1997-09-25 | 2004-10-06 | Macquarie Res Ltd | Vorrichtung zur entfernung einer probe aus einer probenmatrix und schneideverkzeug zum gebrauch mit dieser vorrichtung |
ATE393912T1 (de) | 1998-02-04 | 2008-05-15 | Invitrogen Corp | Microarrays und ihre verwendungen |
US8680059B2 (en) * | 1998-05-20 | 2014-03-25 | Biotempt B.V. | Oligopeptide acetate and formulations thereof |
US20050227925A1 (en) * | 2004-04-08 | 2005-10-13 | Robbert Benner | Compositions capable of reducing elevated blood urea concentration |
US6844315B2 (en) | 1998-05-20 | 2005-01-18 | Erasmus Universiteit Rotterdam | Immunoregulator |
US20030220258A1 (en) | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of ischemic events |
US6921751B1 (en) * | 1998-05-20 | 2005-07-26 | Erasmus Universiteit Rotterdam | Immunoregulator |
US20040202645A1 (en) * | 2003-04-08 | 2004-10-14 | Khan Nisar Ahmed | Administration of gene-regulatory peptides |
GB9811656D0 (en) * | 1998-05-29 | 1998-07-29 | Oxford Glycosciences Uk Ltd | Gels, methods and apparatus for identification and characterization of biomolecules |
US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
US20020119579A1 (en) * | 1998-07-14 | 2002-08-29 | Peter Wagner | Arrays devices and methods of use thereof |
US6780582B1 (en) * | 1998-07-14 | 2004-08-24 | Zyomyx, Inc. | Arrays of protein-capture agents and methods of use thereof |
US20030138973A1 (en) * | 1998-07-14 | 2003-07-24 | Peter Wagner | Microdevices for screening biomolecules |
US6576478B1 (en) * | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
US20040224338A1 (en) * | 1998-08-12 | 2004-11-11 | Zycos Inc., A Delaware Corporation | Profiling and cataloging expressed protein tags |
US6335446B1 (en) | 1998-10-05 | 2002-01-01 | Oxford Glycosciences (Uk) Ltd. | Quinolinium- and pyridinium-based fluorescent dye compounds |
EP1006362A1 (de) * | 1998-12-02 | 2000-06-07 | Michael Dr. Cahill | Methode und Apparat für die Abtrennung von Komponenten aus einem biologischen Material |
US6816259B1 (en) | 1999-02-17 | 2004-11-09 | Kevin Auton | Method and apparatus for automated excision of samples from two-dimensional electrophoresis gels |
AU2679600A (en) | 1999-02-17 | 2000-09-04 | Genomic Solutions, Inc. | Method and apparatus for automated excision of samples from two-dimensional electrophoresis gels |
AUPP930099A0 (en) * | 1999-03-19 | 1999-04-15 | Campbell Corporation Pty Ltd | Improvements in apparatus and method for removing samples |
US6937330B2 (en) | 1999-04-23 | 2005-08-30 | Ppd Biomarker Discovery Sciences, Llc | Disposable optical cuvette cartridge with low fluorescence material |
US6379970B1 (en) * | 1999-04-30 | 2002-04-30 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Analysis of differential protein expression |
EP1059529A1 (de) * | 1999-06-09 | 2000-12-13 | Alfred Prof. Dr. Nordheim | Reversibel angeheftete Gele für Gelelektroforese |
US6687395B1 (en) * | 1999-07-21 | 2004-02-03 | Surromed, Inc. | System for microvolume laser scanning cytometry |
US7214477B1 (en) | 1999-07-26 | 2007-05-08 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Layered device with capture regions for cellular analysis |
US6969615B2 (en) * | 1999-07-26 | 2005-11-29 | 20/20 Genesystems, Inc. | Methods, devices, arrays and kits for detecting and analyzing biomolecules |
US7838222B2 (en) * | 1999-07-26 | 2010-11-23 | United States of America/ NIH | Methods, devices and kits for multiplex blotting of biological samples from multi-well plates |
JP4137444B2 (ja) | 1999-07-26 | 2008-08-20 | ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ | 細胞分析用の捕捉領域を有する層状装置 |
US20030077603A1 (en) * | 1999-08-18 | 2003-04-24 | Parekh Rajesh Bhikhu | Methods and compositions for diagnosis of hepatoma |
US6301377B1 (en) * | 1999-10-05 | 2001-10-09 | Large Scale Proteomics Corporation | Gel electrophoresis image warping |
US7329388B2 (en) | 1999-11-08 | 2008-02-12 | Princeton Biochemicals, Inc. | Electrophoresis apparatus having staggered passage configuration |
US6406604B1 (en) | 1999-11-08 | 2002-06-18 | Norberto A. Guzman | Multi-dimensional electrophoresis apparatus |
US6342143B1 (en) * | 2000-01-06 | 2002-01-29 | Carnegie Mellon University | Cutting tool for multiple sample retrieval from gelatinous material |
CA2298181C (en) | 2000-02-02 | 2006-09-19 | Dayan Burke Goodnough | Non-targeted complex sample analysis |
EP1385869A2 (de) * | 2000-02-08 | 2004-02-04 | The Regents Of The University Of Michigan | Proteinkartierung |
US20080153711A1 (en) * | 2000-02-08 | 2008-06-26 | Regents Of The University Of Michigan | Protein microarray system |
US20080280771A1 (en) * | 2000-02-08 | 2008-11-13 | Regents Of The University Of Michigan | Protein MicroarraySystem |
US6652724B2 (en) | 2001-04-04 | 2003-11-25 | Large Scale Proteomics Corporation | Automated apparatus for separating a biological sample from a two dimensional electrophoresis gel |
EP1300418A1 (de) * | 2001-10-04 | 2003-04-09 | Erasmus Universiteit Rotterdam | Genregulation durch Oligopeptide |
US7358330B2 (en) * | 2001-03-29 | 2008-04-15 | Biotempt B.V. | Immunoregulatory compositions |
USRE43279E1 (en) | 2000-03-29 | 2012-03-27 | Biotemp B.V. | Compositions capable of reducing elevated blood urea concentration |
US6521111B1 (en) * | 2000-04-10 | 2003-02-18 | Invitrogen Corporation | Methods and articles for labeling polymer gels |
CN1654956A (zh) | 2000-05-04 | 2005-08-17 | 耶鲁大学 | 用于筛选蛋白活性的高密度蛋白阵列 |
SE0002041D0 (sv) * | 2000-05-12 | 2000-06-13 | Amersham Pharm Biotech Ab | Gel spot picker |
SE0001780D0 (sv) * | 2000-05-12 | 2000-05-12 | Amersham Pharm Biotech Ab | Spot picker device and method |
AU2001274445A1 (en) * | 2000-06-07 | 2001-12-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method and apparatus for direct coupling of planar chromatography with mass spectrometry |
US20030064372A1 (en) * | 2000-06-22 | 2003-04-03 | Bodnar Jackie S. | Gene and sequence variation associated with lipid disorder |
GB0016010D0 (en) | 2000-06-30 | 2000-08-23 | Amersham Pharm Biotech Ab | Spot picker device and method for picking gel plugs |
AU2001278968A1 (en) * | 2000-07-19 | 2002-01-30 | Pointilliste, Inc. | Nested sorting and high throughput screening |
US20060275851A1 (en) * | 2000-07-26 | 2006-12-07 | Emmert-Buck Michael R | Layered peptide/antigen arrays - for high-throughput antibody screening of clinical samples |
US6404905B1 (en) * | 2000-08-31 | 2002-06-11 | Large Scale Proteomics Corp. | Method and apparatus for impressing a master pattern to a gel image |
JP3998905B2 (ja) * | 2000-09-14 | 2007-10-31 | 日立ソフトウエアエンジニアリング株式会社 | 電気泳動のバンド選択装置及びバンド選択方法 |
GB0022978D0 (en) | 2000-09-19 | 2000-11-01 | Oxford Glycosciences Uk Ltd | Detection of peptides |
AU4323602A (en) * | 2000-11-20 | 2002-06-24 | 20 20 Gene Systems Inc | Methods, devices, arrays and kits for detecting and analyzing biomolecules |
US6787761B2 (en) * | 2000-11-27 | 2004-09-07 | Surromed, Inc. | Median filter for liquid chromatography-mass spectrometry data |
US20020095260A1 (en) * | 2000-11-28 | 2002-07-18 | Surromed, Inc. | Methods for efficiently mining broad data sets for biological markers |
EP1379879A2 (de) * | 2000-12-08 | 2004-01-14 | Oxford GlycoSciences (UK) Limited | Diagnose und behandlung der alzheimer-krankheit |
GB0030051D0 (en) * | 2000-12-08 | 2001-01-24 | Oxford Glycosciences Uk Ltd | Proteins genes and their use for diagnosis and treatment of chronic asthma |
US20030064411A1 (en) * | 2000-12-08 | 2003-04-03 | Herath Herath Mudiyanselage Athula Chandrasiri | Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of Alzheimer's disease |
US20050014193A1 (en) * | 2003-06-17 | 2005-01-20 | Sharma Shubh D. | Identification of target-specific folding sites in peptides and proteins |
US7351690B2 (en) * | 2000-12-19 | 2008-04-01 | Palatin Technologies, Inc. | Knockout identification of target-specific sites in peptides |
EP1364209A4 (de) * | 2001-02-05 | 2004-04-14 | Activx Biosciences Inc | Auf aktivität basierende sondenanalyse |
US6931325B2 (en) | 2001-02-07 | 2005-08-16 | Regents Of The University Of Michigan | Three dimensional protein mapping |
US20040092001A1 (en) * | 2001-03-01 | 2004-05-13 | 3M Innovative Properties Company | Automated imaging and harvesting of colonies on thin film culture devices |
US20030060695A1 (en) * | 2001-03-07 | 2003-03-27 | Connelly Patrick R. | Implantable artificial organ devices |
WO2003002724A2 (en) * | 2001-03-12 | 2003-01-09 | Affinium Pharmaceuticals, Inc. | Proteins, druggable regions of proteins and target analysis for chemistry of therapeutics |
AUPR378001A0 (en) * | 2001-03-16 | 2001-04-12 | Proteome Systems Ltd | Protein chip |
US20050019942A1 (en) * | 2001-03-16 | 2005-01-27 | Proteome Systems Ltd. | Array-based biomolecule analysis |
US20020186875A1 (en) * | 2001-04-09 | 2002-12-12 | Burmer Glenna C. | Computer methods for image pattern recognition in organic material |
WO2002090991A2 (en) * | 2001-05-03 | 2002-11-14 | Oxford Glycosciences (Uk) Ltd | Proteins and genes for diagnosis and treatment of erbb2-related cancer |
US7158888B2 (en) * | 2001-05-04 | 2007-01-02 | Takeda San Diego, Inc. | Determining structures by performing comparisons between molecular replacement results for multiple different biomolecules |
WO2002090966A1 (en) * | 2001-05-10 | 2002-11-14 | Large Scale Proteomics Corporation | Automated apparatus for separating a biological sample from a two dimensional electrophoresis gel |
EP1392342B1 (de) * | 2001-05-11 | 2015-09-23 | Yale University | Globale analyse von proteinaktivitäten unter verwendung von proteom-chips |
AUPR527301A0 (en) * | 2001-05-25 | 2001-06-21 | Proteome Systems Ltd | Liquid handling means for excision apparatus |
JP2002365177A (ja) * | 2001-05-25 | 2002-12-18 | Proteome Systems Ltd | 質量分析用試料の前処理装置 |
CA2349265A1 (en) * | 2001-05-30 | 2002-11-30 | Andrew Emili | Protein expression profile database |
CA2453764A1 (en) * | 2001-07-13 | 2003-01-23 | Syngenta Participations Ag | System and method for storing mass spectrometry data |
CA2453725A1 (en) * | 2001-07-13 | 2003-01-23 | Syngenta Participations Ag | System and method of determining proteomic differences |
EP1414443B1 (de) * | 2001-08-01 | 2006-11-15 | Merck & Co., Inc. | BENZIMIDAZO 4,5-f|ISOCHINOLINON-DERIVATE |
CA2457906A1 (en) * | 2001-08-13 | 2003-07-17 | Late Night Labs Ltd. | System and method for simulating laboratory experiment |
US20030174147A1 (en) * | 2001-08-13 | 2003-09-18 | David Jaffe | Device, system and method for simulating a physical system |
US7133864B2 (en) | 2001-08-23 | 2006-11-07 | Syngenta Participations Ag | System and method for accessing biological data |
US6873915B2 (en) * | 2001-08-24 | 2005-03-29 | Surromed, Inc. | Peak selection in multidimensional data |
US6855554B2 (en) | 2001-09-21 | 2005-02-15 | Board Of Regents, The University Of Texas Systems | Methods and compositions for detection of breast cancer |
US6835927B2 (en) * | 2001-10-15 | 2004-12-28 | Surromed, Inc. | Mass spectrometric quantification of chemical mixture components |
US20030211624A1 (en) * | 2001-11-20 | 2003-11-13 | Board Of Regents, The University Of Texas System | Proteomic methods for diagnosis and monitoring of breast cancer |
US20040002842A1 (en) * | 2001-11-21 | 2004-01-01 | Jeffrey Woessner | Methods and systems for analyzing complex biological systems |
FR2833082B1 (fr) * | 2001-12-03 | 2004-08-27 | Centre Nat Rech Scient | Detection positionnement et dosage de molecules biologiques separees sur une surface, en utilisant la mesure d'une propriete ou effet electrique |
US20080242837A1 (en) * | 2001-12-21 | 2008-10-02 | Khan Nisar A | Peptide compositions |
US20030220257A1 (en) * | 2001-12-21 | 2003-11-27 | Robbert Benner | Treatment of trauma |
US20080318871A1 (en) * | 2001-12-21 | 2008-12-25 | Khan Nisar A | Treatment of neurological disorders |
US7786084B2 (en) * | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
US7560433B2 (en) | 2001-12-21 | 2009-07-14 | Biotempt B.V. | Treatment of multiple sclerosis (MS) |
WO2003058230A1 (en) * | 2002-01-11 | 2003-07-17 | Ludesi Ab | Method and computer program for digital image processing for two-dimensional electrophoresis |
WO2003067904A2 (en) * | 2002-02-06 | 2003-08-14 | University Of North Carolina At Chapel Hill | High-throughput cell identification and isolation method and apparatus |
GB0203924D0 (en) * | 2002-02-19 | 2002-04-03 | Univ Bristol | Screening method |
BR0200690A (pt) * | 2002-03-04 | 2004-03-23 | Embrapa Pesquisa Agropecuaria | Método para detecção de proteinas de origem em misturas complexas |
US20040107057A1 (en) * | 2002-03-22 | 2004-06-03 | Capaldi Roderick A | Enhanced protein separation and analysis |
WO2003095978A2 (en) * | 2002-05-09 | 2003-11-20 | Surromed, Inc. | Methods for time-alignment of liquid chromatography-mass spectrometry data |
EP1576121A4 (de) * | 2002-05-17 | 2008-04-23 | Automated Cell Inc | Proteinfunktionsbestimmung |
EP1384994A1 (de) * | 2002-07-23 | 2004-01-28 | F.Hoffmann-La Roche Ag | Verfahren und Vorrichtung zum Lokalisieren und Ausschneiden von Anreicherungen in einem Gel |
EP1384993A1 (de) * | 2002-07-23 | 2004-01-28 | F. Hoffmann-La Roche Ag | Verfahren und Vorrichtung zum Lokalisieren und Ausschneiden von Anreicherungen in einem Gel |
US6878949B2 (en) | 2002-08-22 | 2005-04-12 | Genextix Limited | Gel imaging and excision |
DE60325482D1 (de) * | 2002-08-22 | 2009-02-05 | Applera Corp | Verfahren zur charakterisierung von biomolekülen mittels resultat-gesteuerter strategie |
US9740817B1 (en) | 2002-10-18 | 2017-08-22 | Dennis Sunga Fernandez | Apparatus for biological sensing and alerting of pharmaco-genomic mutation |
KR20030005086A (ko) * | 2002-11-08 | 2003-01-15 | 주식회사 이롬라이프 | 생식 및 식이섬유를 함유하는 다이어트 조성물 |
US7118708B2 (en) * | 2002-11-12 | 2006-10-10 | Automated Biotechnology, Inc. | System of sample medium carriers with built-in memory elements and information input/output station for the carriers |
AU2003297301A1 (en) * | 2002-11-25 | 2004-06-18 | The United States Of America As Represented By The Secretary Of Health And Human Services, Nih | Method and apparatus for performing multiple simultaneous manipulations of biomolecules in a two-dimensional array |
US20040102903A1 (en) * | 2002-11-27 | 2004-05-27 | Graessle Josef A. | Biological growth plate scanner |
US7351574B2 (en) * | 2002-11-27 | 2008-04-01 | 3M Innovative Properties Company | Loading and ejection systems for biological growth plate scanner |
US20040101954A1 (en) | 2002-11-27 | 2004-05-27 | Graessle Josef A. | Back side plate illumination for biological growth plate scanner |
US7298885B2 (en) * | 2002-11-27 | 2007-11-20 | 3M Innovative Properties Company | Biological growth plate scanner with automated image processing profile selection |
US7319031B2 (en) * | 2002-11-27 | 2008-01-15 | 3M Innovative Properties Company | Mounting platform for biological growth plate scanner |
US7022481B2 (en) * | 2002-12-19 | 2006-04-04 | Rosetta Inpharmatics Llc | Methods of using glucan synthase pathway reporter genes to screen for antifungal compounds |
EP1587840B1 (de) * | 2003-01-13 | 2008-08-20 | The Regents Of The University Of Michigan | Verfahren zur bildung eines protein-mikroarraysystems |
US7422865B2 (en) * | 2003-01-13 | 2008-09-09 | Agilent Technologies, Inc. | Method of identifying peptides in a proteomic sample |
EP1447412A1 (de) * | 2003-02-17 | 2004-08-18 | Universiteit Utrecht Holding B.V. | Verfahren zur Bestimmung von Proteinen, isolierte Proteine und deren Verwendungen |
US7227984B2 (en) * | 2003-03-03 | 2007-06-05 | Kla-Tencor Technologies Corporation | Method and apparatus for identifying defects in a substrate surface by using dithering to reconstruct under-sampled images |
US6956208B2 (en) * | 2003-03-17 | 2005-10-18 | Indiana University Research And Technology Corporation | Method and apparatus for controlling position of a laser of a MALDI mass spectrometer |
US20040183009A1 (en) * | 2003-03-17 | 2004-09-23 | Reilly James P. | MALDI mass spectrometer having a laser steering assembly and method of operating the same |
US6861647B2 (en) * | 2003-03-17 | 2005-03-01 | Indiana University Research And Technology Corporation | Method and apparatus for mass spectrometric analysis of samples |
US20050233390A1 (en) * | 2003-04-09 | 2005-10-20 | Allen John W | Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor |
WO2004097368A2 (en) * | 2003-04-28 | 2004-11-11 | Ciphergen Biosystems, Inc. | Improved immunoassays |
US20040248323A1 (en) * | 2003-06-09 | 2004-12-09 | Protometrix, Inc. | Methods for conducting assays for enzyme activity on protein microarrays |
US7860727B2 (en) * | 2003-07-17 | 2010-12-28 | Ventana Medical Systems, Inc. | Laboratory instrumentation information management and control network |
US8719053B2 (en) * | 2003-07-17 | 2014-05-06 | Ventana Medical Systems, Inc. | Laboratory instrumentation information management and control network |
US20080235055A1 (en) * | 2003-07-17 | 2008-09-25 | Scott Mattingly | Laboratory instrumentation information management and control network |
RU2359270C2 (ru) * | 2003-07-29 | 2009-06-20 | Зольвай Фармасьютиклз Гмбх | Способ анализа панкреатита и содержащих его композиций |
US20080050720A1 (en) * | 2003-07-30 | 2008-02-28 | Phillips John W | Methods for Using a Sterol Biosynthesis Pathway Reporter Gene to Screen for Antifungal or Lipid Lowering Compounds |
US7776584B2 (en) * | 2003-08-01 | 2010-08-17 | Genetix Limited | Animal cell colony picking apparatus and method |
IL157206A0 (en) * | 2003-08-03 | 2004-02-19 | Correlating spatial position of chemical species on a substrate with molecular weight, structure and chemical reactivity | |
US8346482B2 (en) | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
US7496225B2 (en) * | 2003-09-04 | 2009-02-24 | 3M Innovative Properties Company | Biological growth plate scanner with automated intake |
US7298886B2 (en) * | 2003-09-05 | 2007-11-20 | 3M Innovative Properties Company | Counting biological agents on biological growth plates |
EP1706735B1 (de) * | 2003-11-07 | 2017-01-04 | Princeton Biochemicals, Inc. | Mehrdimensionale elektrophoresevorrichtung |
US8030092B2 (en) | 2003-11-07 | 2011-10-04 | Princeton Biochemicals, Inc. | Controlled electrophoresis method |
US20090227505A1 (en) * | 2004-01-07 | 2009-09-10 | Biotempt B.V. | Methods and uses for protein breakdown products |
US7187286B2 (en) | 2004-03-19 | 2007-03-06 | Applera Corporation | Methods and systems for using RFID in biological field |
WO2005092370A1 (en) * | 2004-03-22 | 2005-10-06 | Solvay Pharmaceuticals Gmbh | Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants |
US7248360B2 (en) * | 2004-04-02 | 2007-07-24 | Ppd Biomarker Discovery Sciences, Llc | Polychronic laser scanning system and method of use |
US7247275B2 (en) * | 2004-06-21 | 2007-07-24 | Jeremy Scot Caldwell | Gel extraction device |
US8054857B2 (en) * | 2004-10-07 | 2011-11-08 | Lsi Corporation | Task queuing methods and systems for transmitting frame information over an I/O interface |
WO2007004869A2 (en) * | 2005-07-05 | 2007-01-11 | Biotempt B.V. | Treatment of tumors |
GB0514553D0 (en) * | 2005-07-15 | 2005-08-24 | Nonlinear Dynamics Ltd | A method of analysing a representation of a separation pattern |
GB0514555D0 (en) * | 2005-07-15 | 2005-08-24 | Nonlinear Dynamics Ltd | A method of analysing separation patterns |
EP1913138B1 (de) | 2005-07-29 | 2016-08-24 | Abbott Laboratories GmbH | Verfahren zur herstellung von pankreatin-pulver mit einem niedrigen virusgehalt |
US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
KR20080049821A (ko) | 2005-09-12 | 2008-06-04 | 페노미넘 디스커버리스 인코포레이티드 | 비타민 e-관련 대사산물의 측정에 의한 결장암 및난소암의 진단방법 |
WO2007073367A1 (en) | 2005-12-20 | 2007-06-28 | Jeremy Caldwell | Tool for extracting electrophoretic sample |
EP1864692A1 (de) * | 2006-06-07 | 2007-12-12 | Biotempt B.V. | Verwendung von peptiden zum Schutz von Strahlenschäden |
US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
GB0611116D0 (en) | 2006-06-06 | 2006-07-19 | Oxford Genome Sciences Uk Ltd | Proteins |
US8009889B2 (en) | 2006-06-27 | 2011-08-30 | Affymetrix, Inc. | Feature intensity reconstruction of biological probe array |
US20080220442A1 (en) * | 2006-12-06 | 2008-09-11 | Proteinics | Difference detection methods using isoelectric focusing chips |
PT2120991E (pt) * | 2007-02-12 | 2014-05-02 | Biotempt Bv | Tratamento d a hemorragia traumática com oligopéptidos curtos |
EP2121745A2 (de) | 2007-02-26 | 2009-11-25 | Oxford Genome Sciences (UK) Limited | Proteine |
WO2008104803A2 (en) | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
US20080217002A1 (en) * | 2007-03-07 | 2008-09-11 | Floyd Randolph Simonds | Sand control screen having a micro-perforated filtration layer |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
US9933446B2 (en) | 2008-03-04 | 2018-04-03 | 3M Innovative Properties Company | Processing of biological growth media based on measured manufacturing characteristics |
US8417013B2 (en) | 2008-03-04 | 2013-04-09 | 3M Innovative Properties Company | Information management in automated processing of biological growth media |
WO2011054007A1 (en) | 2009-11-02 | 2011-05-05 | Oxford Biotherapeutics Ltd. | Ror1 as therapeutic and diagnostic target |
WO2012135849A1 (en) * | 2011-04-01 | 2012-10-04 | Life Technologies Corporation | Computer - controlled gel electrophoresis system |
ES2668797T3 (es) * | 2011-06-16 | 2018-05-22 | British Columbia Cancer Agency Branch | Selección automatizada por tamaños de ácidos nucleicos |
US20140234903A1 (en) | 2011-09-05 | 2014-08-21 | Eth Zurich | Biosynthetic gene cluster for the production of peptide/protein analogues |
ES2785222T3 (es) | 2011-09-29 | 2020-10-06 | Bd Kiestra Bv | Método para recolectar material celular y conjunto para llevar a cabo dicho método |
CN102399888A (zh) * | 2011-11-28 | 2012-04-04 | 江苏省农业科学院 | 水稻胡麻叶斑病原菌的分子鉴定方法 |
US9230185B1 (en) * | 2012-03-30 | 2016-01-05 | Pierce Biotechnology, Inc. | Analysis of electrophoretic bands in a substrate |
AU2013267450B2 (en) * | 2012-05-29 | 2017-07-06 | Helena Laboratories Corporation | Composition and method for gel electrophoresis with in-situ calibration |
US9091628B2 (en) | 2012-12-21 | 2015-07-28 | L-3 Communications Security And Detection Systems, Inc. | 3D mapping with two orthogonal imaging views |
JP5569761B1 (ja) * | 2013-03-29 | 2014-08-13 | シャープ株式会社 | 分析方法 |
JP5594501B1 (ja) | 2013-04-11 | 2014-09-24 | 株式会社昇竜建設 | ゲルプレートの小片化・分注装置及び小片化・分注方法 |
CN104611306B (zh) * | 2015-02-13 | 2019-10-18 | 北京大北农科技集团股份有限公司 | 除草剂抗性蛋白质、其编码基因及用途 |
CN105802933B (zh) * | 2016-03-22 | 2020-05-05 | 北京大北农科技集团股份有限公司 | 除草剂耐受性蛋白质、其编码基因及用途 |
CN105766992B (zh) * | 2016-03-22 | 2018-06-22 | 北京大北农科技集团股份有限公司 | 除草剂耐受性蛋白质的用途 |
CN105746255B (zh) * | 2016-03-22 | 2019-01-11 | 北京大北农科技集团股份有限公司 | 除草剂耐受性蛋白质的用途 |
CN108693002B (zh) * | 2017-04-07 | 2021-04-13 | 中国医学科学院药物研究所 | 一种模拟生物组织薄片、其制备方法及其应用与装置 |
WO2019038245A1 (de) * | 2017-08-24 | 2019-02-28 | Merck Patent Gmbh | Verfahren und vorrichtung zur bereitstellung einer substanzmenge |
EP3679580A4 (de) * | 2017-09-05 | 2021-04-07 | SRI International | Durch massenspektrometrie unterscheidbare synthetische verbindungen, bibliotheken und verfahren dafür |
WO2019152563A1 (en) | 2018-01-30 | 2019-08-08 | Life Technologies Corporation | Instruments, devices and consumables for use in a workflow of a smart molecular analysis system |
CN109709199B (zh) * | 2019-03-01 | 2024-04-12 | 黄河科技学院 | 血清脂蛋白琼脂糖凝胶电泳开槽器及支架 |
CN114761992B (zh) * | 2019-10-01 | 2023-08-08 | 10X基因组学有限公司 | 用于识别组织样品中的形态学模式的系统和方法 |
CN114397348A (zh) * | 2021-12-28 | 2022-04-26 | 苏州中析生物信息有限公司 | 一种移液电泳全自动一体机 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3499360A (en) * | 1968-02-12 | 1970-03-10 | Charles L Davis | Pattern cutting device and indexing system |
DE2823360C3 (de) | 1978-05-29 | 1981-06-25 | Texas Instruments Deutschland Gmbh, 8050 Freising | Vorrichtung zur Überführung von Gegenständen |
US4341735A (en) | 1980-03-28 | 1982-07-27 | American Cyanamid Company | Sample carrier material handling apparatus |
DE3032069C2 (de) * | 1980-08-26 | 1982-06-16 | Nikolaus Dr. 6900 Heidelberg Grubhofer | Lackartige Haftvermittler für wäßrige Polyacrylamid-Gele auf glatten Polyester-Folien, Verfahren zu ihrer Herstellung und ihre Verwendung für die Elektrophorese |
US4613573A (en) | 1982-05-20 | 1986-09-23 | Hitachi, Ltd. | Automatic bacterial colony transfer apparatus |
JPS59166850A (ja) * | 1983-03-11 | 1984-09-20 | Fuji Photo Film Co Ltd | 電気泳動用媒体材料 |
JPS59164950A (ja) * | 1983-03-11 | 1984-09-18 | Fuji Photo Film Co Ltd | 電気泳動用媒体材料 |
JPS59212752A (ja) * | 1983-05-19 | 1984-12-01 | Fuji Photo Film Co Ltd | 電気泳動用媒体材料 |
US4592089A (en) * | 1983-08-15 | 1986-05-27 | Bio Image Corporation | Electrophoretogram analytical image processing system |
FR2563343B1 (fr) | 1984-04-19 | 1986-06-13 | Rhone Poulenc Sante | Dispositif pour effectuer des prelevements dans des milieux semi-solides |
JPS60243551A (ja) * | 1984-05-18 | 1985-12-03 | Fuji Photo Film Co Ltd | 電気泳動用媒体材料の製造法 |
EP0162693A3 (de) * | 1984-05-21 | 1988-05-11 | Fuji Photo Film Co., Ltd. | Elektrophoretischer Bestandteil |
US4897306A (en) * | 1986-04-19 | 1990-01-30 | Fuji Photo Film Co., Ltd. | Medium for electrophoresis |
US4865707A (en) * | 1986-10-21 | 1989-09-12 | Northeastern University | Capillary gel electrophoresis columns |
US5275710A (en) | 1990-05-14 | 1994-01-04 | Labintelligence, Inc. | Gel electrophoresis system including optical stage, sample applicator and sample retriever |
US5217591A (en) * | 1990-05-14 | 1993-06-08 | Labintelligence, Inc. | Gel electrophoresis sample applicator/retriever |
US5073963A (en) * | 1990-05-25 | 1991-12-17 | Arizona Technology Development Corp. | Computerized method of matching two-dimensional (2-d) patterns |
US5098539A (en) * | 1991-04-19 | 1992-03-24 | Beckman Instruments, Inc. | Gel-containing microcapillary column |
US5301671A (en) * | 1991-09-17 | 1994-04-12 | The United States Of America As Represented By The Department Of Health And Human Services | Two- and three-dimensional autoradiographic imaging utilizing charge coupled devices |
JP3067347B2 (ja) | 1991-10-30 | 2000-07-17 | 株式会社島津製作所 | ゲル状ビーズの選別装置 |
JPH07503542A (ja) * | 1992-01-31 | 1995-04-13 | ベックマン インスツルメンツ インコーポレーテッド | 除去できる分離ゲル組成物を含有する毛管カラム及びその使用方法 |
US5340461A (en) * | 1992-02-03 | 1994-08-23 | Nakano Vinegar Co., Ltd. | Electrophoretic medium for electrophoretic separation, gel holder for holding the same medium, slab type electrophoretic apparatus using the same medium and gel holder, and electrophoretic gel cutter |
EP0738338A4 (de) * | 1993-11-17 | 1997-03-05 | Applied Hydrogel Technology Co | Verfahren für die trennung von biologischen stoffen |
US5631734A (en) * | 1994-02-10 | 1997-05-20 | Affymetrix, Inc. | Method and apparatus for detection of fluorescently labeled materials |
JPH07260742A (ja) * | 1994-03-23 | 1995-10-13 | Sanyo Electric Co Ltd | 電気泳動装置 |
SE9404274D0 (sv) * | 1994-12-08 | 1994-12-08 | Pharmacia Biotech Ab | Anordning vid en gelelektroforesapparat |
US5710628A (en) * | 1994-12-12 | 1998-01-20 | Visible Genetics Inc. | Automated electrophoresis and fluorescence detection apparatus and method |
US6127134A (en) | 1995-04-20 | 2000-10-03 | Carnegie Mellon University | Difference gel electrophoresis using matched multiple dyes |
WO1996039625A1 (en) * | 1995-06-06 | 1996-12-12 | Beltronics Inc. | Automatic protein and/or dna analysis system and method |
US6660233B1 (en) * | 1996-01-16 | 2003-12-09 | Beckman Coulter, Inc. | Analytical biochemistry system with robotically carried bioarray |
US5587062A (en) * | 1996-01-24 | 1996-12-24 | Shimadzu Corporation | Sample collecting apparatus by gel electrophoresis |
US5717602A (en) * | 1996-02-05 | 1998-02-10 | Kenning; Gregory G. | Automated electrophoresis and analysis system |
US6068753A (en) * | 1996-05-06 | 2000-05-30 | Helena Laboratories Corporation | Automatic electrophoresis apparatus with fluorescent and visible scanning |
US5949899A (en) * | 1996-10-01 | 1999-09-07 | Nebular Vision Research & Development Inc. | Apparatus for measuring and analyzing electrophoresis images |
GB9624927D0 (en) * | 1996-11-29 | 1997-01-15 | Oxford Glycosciences Uk Ltd | Gels and their use |
US5993627A (en) | 1997-06-24 | 1999-11-30 | Large Scale Biology Corporation | Automated system for two-dimensional electrophoresis |
-
1996
- 1996-11-29 GB GBGB9624927.1A patent/GB9624927D0/en active Pending
-
1997
- 1997-12-01 EP EP03000559A patent/EP1302768A3/de not_active Withdrawn
- 1997-12-01 AU AU52300/98A patent/AU713259B2/en not_active Ceased
- 1997-12-01 AT AT97947150T patent/ATE236392T1/de not_active IP Right Cessation
- 1997-12-01 WO PCT/GB1997/003307 patent/WO1998023950A1/en active IP Right Grant
- 1997-12-01 US US08/980,574 patent/US6064754A/en not_active Expired - Fee Related
- 1997-12-01 CN CN97181104A patent/CN1125981C/zh not_active Expired - Fee Related
- 1997-12-01 CA CA002272092A patent/CA2272092C/en not_active Expired - Fee Related
- 1997-12-01 JP JP52445098A patent/JP3462220B2/ja not_active Expired - Fee Related
- 1997-12-01 DK DK97947150T patent/DK0941477T3/da active
- 1997-12-01 EP EP97947150A patent/EP0941477B1/de not_active Revoked
- 1997-12-01 DE DE69720505T patent/DE69720505T2/de not_active Expired - Fee Related
- 1997-12-01 ZA ZA9710792A patent/ZA9710792B/xx unknown
-
1999
- 1999-05-28 NO NO992583A patent/NO992583L/no not_active Application Discontinuation
-
2000
- 2000-02-08 US US09/500,775 patent/US6278794B1/en not_active Expired - Fee Related
- 2000-11-28 US US09/724,399 patent/US6480618B1/en not_active Expired - Fee Related
-
2002
- 2002-08-22 US US10/226,951 patent/US20020191825A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69720505T2 (de) | 2004-03-04 |
EP0941477A1 (de) | 1999-09-15 |
US20020191825A1 (en) | 2002-12-19 |
CN1242076A (zh) | 2000-01-19 |
US6278794B1 (en) | 2001-08-21 |
WO1998023950A1 (en) | 1998-06-04 |
EP1302768A3 (de) | 2004-04-14 |
GB9624927D0 (en) | 1997-01-15 |
EP0941477B1 (de) | 2003-04-02 |
NO992583D0 (no) | 1999-05-28 |
US6480618B1 (en) | 2002-11-12 |
AU713259B2 (en) | 1999-11-25 |
EP1302768A2 (de) | 2003-04-16 |
CA2272092C (en) | 2004-03-30 |
US6064754A (en) | 2000-05-16 |
JP3462220B2 (ja) | 2003-11-05 |
AU5230098A (en) | 1998-06-22 |
DK0941477T3 (da) | 2003-07-28 |
NO992583L (no) | 1999-07-28 |
CN1125981C (zh) | 2003-10-29 |
ZA9710792B (en) | 1998-12-01 |
JP2001504938A (ja) | 2001-04-10 |
ATE236392T1 (de) | 2003-04-15 |
CA2272092A1 (en) | 1998-06-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69720505D1 (de) | Verfahren und vorrichtung zur identifizierung und charakterisierung von biomolekuelen | |
DE69517864T2 (de) | Verfahren und Vorrichtung zur Zählung und Klassifizierung von Zellen | |
ATE253645T1 (de) | Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien | |
DE3587427D1 (de) | Hybridisierungsverfahren zum nachweis genetischer stoffe. | |
DE60230927D1 (de) | Fangverbindungen, ihre entnahme und verfahren zur analysierung des proteoms und von komplexen zusammensetzungen | |
DE60040603D1 (de) | Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten | |
DE69228158T2 (de) | Verfahren zur Charakterisierung genomischer DNA | |
ATE245278T1 (de) | Verfahren zur automatischen analyse von mikroskopaufnahmen | |
WO1999063351A3 (en) | Method for identification and characterisation of biomolecules | |
DE69113960D1 (de) | ATR-Objektiv und Verfahren zur Probenuntersuchung. | |
DE58900667D1 (de) | Verfahren zur aufarbeitung kontaminierter oele. | |
EP1418238A4 (de) | Vorrichtung und verfahren zur untersuchung von mikroben | |
ATE186575T1 (de) | Verfahren zur identifizierung von menschlichen und tierischen zellen mit der fähigkeit zu unbegrenzter proliferation oder zur tumorbildung | |
AU2002344839B2 (en) | Flat field correction of two-dimensional biochemical assay images | |
EP1281969A3 (de) | Verfahren und Vorrichtung zum Bestimmen von Proteinen auf einem Reaktionsträger | |
DE602004015932D1 (de) | Verfahren zur bildung eines protein-mikroarraysystems | |
DE69927691D1 (de) | Verfahren zur eiweissanalyse | |
AU2002344839A1 (en) | Flat field correction of two-dimensional biochemical assay images | |
EP1491638A3 (de) | Vorrichtung und Methode zur Bestimmung von Nukleinsäuren in bestimmter Reihenfolge | |
WO2001007920A3 (en) | Automated landmarking for two-dimensional electrophoresis | |
EP0840115A3 (de) | DNA-Basen Sequenzer | |
ATE161698T1 (de) | Verfahren und anordnung zur darstellung von strukturen | |
LANGLEY | TWO-DIMENSIONAL ELECTROPHORETIC ANALYSIS OF MICROSPORIDAN SPORE PROTEINS. | |
DE29708151U1 (de) | Vorrichtung zur automatisierten Sortierung von runden Objekten nach optischen Qualitätskriterien | |
DE69216086T2 (de) | Verfahren zur gewinnung von zellen, die informationen tragen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8339 | Ceased/non-payment of the annual fee |