DE69718495T2 - System zur medikamentenabgabe durch transport - Google Patents

System zur medikamentenabgabe durch transport

Info

Publication number
DE69718495T2
DE69718495T2 DE69718495T DE69718495T DE69718495T2 DE 69718495 T2 DE69718495 T2 DE 69718495T2 DE 69718495 T DE69718495 T DE 69718495T DE 69718495 T DE69718495 T DE 69718495T DE 69718495 T2 DE69718495 T2 DE 69718495T2
Authority
DE
Germany
Prior art keywords
dermis
fluid
micropenetrators
epidermis
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69718495T
Other languages
English (en)
Other versions
DE69718495D1 (de
Inventor
L Kamen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deka Products LP
Original Assignee
Deka Products LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deka Products LP filed Critical Deka Products LP
Publication of DE69718495D1 publication Critical patent/DE69718495D1/de
Application granted granted Critical
Publication of DE69718495T2 publication Critical patent/DE69718495T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Refuse Collection And Transfer (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgical Instruments (AREA)
DE69718495T 1996-09-17 1997-09-15 System zur medikamentenabgabe durch transport Expired - Lifetime DE69718495T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2626696P 1996-09-17 1996-09-17
US3903697P 1997-02-24 1997-02-24
PCT/US1997/016454 WO1998011937A1 (en) 1996-09-17 1997-09-15 System for delivery of drugs by transport

Publications (2)

Publication Number Publication Date
DE69718495D1 DE69718495D1 (de) 2003-02-20
DE69718495T2 true DE69718495T2 (de) 2003-11-20

Family

ID=26700996

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718495T Expired - Lifetime DE69718495T2 (de) 1996-09-17 1997-09-15 System zur medikamentenabgabe durch transport

Country Status (7)

Country Link
US (1) US5983136A (de)
EP (1) EP0934093B1 (de)
JP (2) JP4054381B2 (de)
AT (1) ATE231015T1 (de)
CA (1) CA2265906C (de)
DE (1) DE69718495T2 (de)
WO (1) WO1998011937A1 (de)

Families Citing this family (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037256A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
US7214847B1 (en) 1997-09-22 2007-05-08 Argentum Medical, L.L.C. Multilayer conductive appliance having wound healing and analgesic properties
US6861570B1 (en) * 1997-09-22 2005-03-01 A. Bart Flick Multilayer conductive appliance having wound healing and analgesic properties
US8455710B2 (en) * 1997-09-22 2013-06-04 Argentum Medical, Llc Conductive wound dressings and methods of use
US8801681B2 (en) * 1995-09-05 2014-08-12 Argentum Medical, Llc Medical device
US5814094A (en) 1996-03-28 1998-09-29 Becker; Robert O. Iontopheretic system for stimulation of tissue healing and regeneration
US6230051B1 (en) * 1996-06-18 2001-05-08 Alza Corporation Device for enhancing transdermal agent delivery or sampling
EP2428249B1 (de) * 1998-07-13 2015-10-07 Inovio Pharmaceuticals, Inc. Haut- und muskelgerichtete Gentherapie mithilfe eines gepulsten elektrischen Felds
US7922709B2 (en) 1998-07-13 2011-04-12 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
US6678556B1 (en) * 1998-07-13 2004-01-13 Genetronics, Inc. Electrical field therapy with reduced histopathological change in muscle
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6502574B2 (en) 1999-09-17 2003-01-07 Pi Medical, Inc. Lateral stiffening snoring treatment
US6431174B1 (en) 2000-08-10 2002-08-13 Pi Medical, Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US6231561B1 (en) * 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
CN1390148A (zh) * 1999-11-15 2003-01-08 维尔克鲁工业公司 皮肤附着件
EP1239916B1 (de) 1999-12-10 2005-11-23 ALZA Corporation Vorrichtung und verfahren zur verbesserung des mikronadel-haut-piercing
US6497676B1 (en) 2000-02-10 2002-12-24 Baxter International Method and apparatus for monitoring and controlling peritoneal dialysis therapy
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6659982B2 (en) * 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
NZ524646A (en) 2000-09-08 2004-10-29 Alza Corp Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure
CN1250171C (zh) 2000-10-13 2006-04-12 阿尔扎公司 利用微凸起刺入皮肤的装置和方法
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
JP4198985B2 (ja) 2000-10-13 2008-12-17 アルザ・コーポレーシヨン マイクロブレードアレー衝撃アプリケータ。
MXPA03003303A (es) * 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
ATE428466T1 (de) 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
MXPA03006852A (es) 2001-01-31 2004-05-31 Velcro Ind Acoplamiento de gancho directo.
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
EP1752189A3 (de) 2001-04-20 2007-02-21 Alza Corporation Mikroprojektionsanordnung mit einem Überzug, der ein vorteilhaftes Mittel enthält
MXPA03009603A (es) * 2001-04-20 2004-12-06 Johnson & Johnson Arreglo de microproyeccion que tiene un agente benefico que contiene un recubrimiento.
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
JP2005511248A (ja) * 2001-10-29 2005-04-28 ベクトン・ディキンソン・アンド・カンパニー 物質を送達するための方法およびデバイス
US20030125662A1 (en) 2002-01-03 2003-07-03 Tuan Bui Method and apparatus for providing medical treatment therapy based on calculated demand
US7146981B2 (en) * 2002-02-04 2006-12-12 Restore Medical, Inc. Pharyngeal wall treatment
US7017582B2 (en) * 2002-02-04 2006-03-28 Restore Medical Inc. Stiffening pharyngeal wall treatment
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
AU2003265226A1 (en) 2002-03-11 2003-12-19 Altea Therapeutics Corporation Transdermal drug delivery device, method and use
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
KR20120087197A (ko) 2002-07-19 2012-08-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
US7238164B2 (en) 2002-07-19 2007-07-03 Baxter International Inc. Systems, methods and apparatuses for pumping cassette-based therapies
US20040194266A1 (en) * 2002-08-19 2004-10-07 Carter Linda A. Burn, sunburn, and cellulite treatment system
CA2497154C (en) * 2002-08-29 2012-01-03 Becton, Dickinson And Company Substance delivery via a rotating microabrading surface
US8062573B2 (en) * 2002-09-16 2011-11-22 Theraject, Inc. Solid micro-perforators and methods of use
US20040236269A1 (en) 2002-09-25 2004-11-25 Marchitto Kevin S. Microsurgical tissue treatment system
US7390330B2 (en) 2002-09-27 2008-06-24 Surgitech, Llc Reciprocating surgical file
US7666186B2 (en) * 2002-09-27 2010-02-23 Surgitech, Llc Surgical system with a blade
US20060264926A1 (en) * 2002-11-08 2006-11-23 Kochamba Gary S Cutaneous stabilization by vacuum for delivery of micro-needle array
US6896666B2 (en) * 2002-11-08 2005-05-24 Kochamba Family Trust Cutaneous injection delivery under suction
US7381222B2 (en) * 2002-12-30 2008-06-03 Quiescence Medical, Inc. Stent for maintaining patency of a body region
US7992566B2 (en) 2002-12-30 2011-08-09 Quiescence Medical, Inc. Apparatus and methods for treating sleep apnea
US7647931B2 (en) 2002-12-30 2010-01-19 Quiescence Medical, Inc. Stent for maintaining patency of a body region
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
CA2530531A1 (en) 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
AR044985A1 (es) * 2003-07-02 2005-10-12 Alza Corp Metodo y parche de inmunizacion por disposicion de microproyeccion
US8961477B2 (en) 2003-08-25 2015-02-24 3M Innovative Properties Company Delivery of immune response modifier compounds
CA2536443A1 (en) * 2003-08-26 2005-03-03 Alza Corporation Device and method for intradermal cell implantation
US8016811B2 (en) * 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
JP2007510445A (ja) 2003-10-24 2007-04-26 アルザ・コーポレーシヨン 経皮薬剤送達促進用の前処置法及びシステム
BRPI0415986A (pt) 2003-10-28 2007-01-23 Alza Corp método e aparelho para reduzir a incidência do uso de tabaco
JP4682144B2 (ja) 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
EP1706171A1 (de) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medizinprodukte und diese enthaltende sets
JP2007523771A (ja) * 2004-02-23 2007-08-23 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの成形方法
WO2005094526A2 (en) 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
WO2005123173A1 (en) * 2004-06-10 2005-12-29 3M Innovative Properties Company Patch application device and kit
US7316665B2 (en) * 2004-08-25 2008-01-08 Becton, Dickinson And Company Method and device for the delivery of a substance including a covering
KR20070099540A (ko) * 2004-09-08 2007-10-09 알자 코포레이션 향상된 피부 점착성 및 순응도를 갖는 미세돌출부 어레이
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
BRPI0517749A (pt) 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
KR101224257B1 (ko) * 2004-11-18 2013-01-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 어레이를 코팅하기 위한 마스킹 방법
US9174035B2 (en) 2004-11-18 2015-11-03 3M Innovative Properties Company Microneedle array applicator and retainer
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
US20080307849A1 (en) * 2004-11-26 2008-12-18 Agency For Science, Technology And Research Method And Apparatus For Forming Microstructures
AU2005314151B2 (en) 2004-12-07 2011-09-08 3M Innovative Properties Company Method of molding a microneedle
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
EP1904158B1 (de) 2005-06-24 2013-07-24 3M Innovative Properties Company Faltbares Pflaster mit Mikronadelnanordnung
ATE477833T1 (de) * 2005-06-27 2010-09-15 3M Innovative Properties Co Mikronadelkartuschenanordnung
JP5144510B2 (ja) 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイ適用装置
CN101687094B (zh) * 2005-09-06 2012-09-26 谢拉杰克特股份有限公司 含有药物颗粒和/或药物吸附颗粒的固体溶液穿孔器
WO2007061964A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Methods for coating microneedles
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
US20070142885A1 (en) * 2005-11-29 2007-06-21 Reliant Technologies, Inc. Method and Apparatus for Micro-Needle Array Electrode Treatment of Tissue
WO2007075614A1 (en) * 2005-12-21 2007-07-05 3M Innovative Properties Company Microneedle devices
WO2007124411A1 (en) 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
WO2008006090A2 (en) 2006-07-06 2008-01-10 Quiescence Medical, Inc. Apparatus and methods for treating sleep apnea
WO2008091602A2 (en) 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
US8558964B2 (en) 2007-02-15 2013-10-15 Baxter International Inc. Dialysis system having display with electromagnetic compliance (“EMC”) seal
US7998115B2 (en) 2007-02-15 2011-08-16 Baxter International Inc. Dialysis system having optical flowrate detection
US8361023B2 (en) 2007-02-15 2013-01-29 Baxter International Inc. Dialysis system with efficient battery back-up
US7731689B2 (en) 2007-02-15 2010-06-08 Baxter International Inc. Dialysis system having inductive heating
US8870812B2 (en) 2007-02-15 2014-10-28 Baxter International Inc. Dialysis system having video display with ambient light adjustment
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2244746B2 (de) † 2008-02-27 2019-01-02 Aplion Medical Corporation Wundverbandvorrichtung mit gleichmässiger verteilung
CN102105108B (zh) * 2008-05-21 2013-12-04 谢拉杰克特股份有限公司 制作固体溶液穿孔器贴剂的方法及其使用
AU2011248108B2 (en) 2010-05-04 2016-05-26 Corium Pharma Solutions, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
WO2012078649A1 (en) 2010-12-06 2012-06-14 Follica, Inc. Methods for treating baldness and promoting hair growth
US9265649B2 (en) 2010-12-13 2016-02-23 Quiescence Medical, Inc. Apparatus and methods for treating sleep apnea
CN105073178B (zh) 2012-12-21 2019-07-30 考里安国际公司 用于治疗剂递送的微阵列及其使用方法
WO2014126101A1 (ja) 2013-02-13 2014-08-21 久光製薬株式会社 マイクロニードル・アレイ
WO2014164314A1 (en) 2013-03-12 2014-10-09 Corium International, Inc. Microprojection applicators
EP2968118B1 (de) 2013-03-15 2022-02-09 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur verwendung
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル， インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
EP2968116A1 (de) 2013-03-15 2016-01-20 Corium International, Inc. Mikroarray mit polymerfreien mikrostrukturen, verfahren zur herstellung und verfahren zur verwendung
US20150038897A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-Profile Microneedle Patch Applicator
EP2905047A1 (de) * 2014-02-10 2015-08-12 LTS LOHMANN Therapie-Systeme AG Mikronadelsystem und Verfahren seiner Herstellung
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3380061A4 (de) 2015-11-24 2019-07-24 Insulet Corporation Automatisiertes wearable-arzneimittelabgabesystem
US11179516B2 (en) 2017-06-22 2021-11-23 Baxter International Inc. Systems and methods for incorporating patient pressure into medical fluid delivery
KR102291392B1 (ko) * 2018-03-30 2021-08-20 랩앤피플주식회사 멀티형 마이크로 니들
US20230277759A1 (en) 2022-03-03 2023-09-07 Deka Products Limited Partnership Systems, Methods, and Apparatuses for Medical Agent Administration
US20240024566A1 (en) 2022-07-21 2024-01-25 Deka Products Limited Partnership Delivery Device Systems, Methods, and Apparatuses

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3617613A (en) * 1968-10-17 1971-11-02 Spaulding Fibre Co Punchable printed circuit board base
US3675766A (en) * 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
BR7908937A (pt) * 1978-12-06 1981-06-30 Svedman Paul Dispositivo para tratamento de tecidos,por exemplo,pele
US4403609A (en) * 1981-02-24 1983-09-13 Cohen Edgar C Vacuum-compression injector
US4421508A (en) * 1981-02-24 1983-12-20 Cohen Edgar C Vacuum-compression injector
US4340048A (en) * 1981-03-28 1982-07-20 Alza Corporation Self-driven hypodermic injector
US4447225A (en) * 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
EP0209644A1 (de) * 1985-05-02 1987-01-28 Ivac Corporation Elektrochemikalisch gesteuerte Arzneimittelabgabevorrichtung
US4711247A (en) * 1986-04-18 1987-12-08 Henry Fishman Allergy testing method and apparatus
US5080648A (en) * 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
DE3735137A1 (de) * 1987-10-16 1989-05-03 Siemens Ag Anordnung zum abgeben von medikamenten bei einem implantierbaren medizinischen geraet
EP0347190A1 (de) * 1988-06-14 1989-12-20 Vci Corporation Nadellose Vakuum-Druck-Spritze
GB2221394B (en) * 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
JPH02144077A (ja) * 1988-11-25 1990-06-01 Olympus Optical Co Ltd 薬物投与装置
EP0429842B1 (de) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
SE9101022D0 (sv) * 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5312456A (en) * 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
US5153986A (en) * 1991-07-17 1992-10-13 International Business Machines Method for fabricating metal core layers for a multi-layer circuit board
US5484399A (en) * 1992-02-27 1996-01-16 Sloan-Kettering Institute For Cancer Research Process and device to reduce interstitial fluid pressure in tissue
US5309909A (en) * 1992-05-22 1994-05-10 Physio-Control Corporation Combined skin preparation and monitoring electrode
US5702359A (en) * 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
IE68890B1 (en) * 1993-04-08 1996-07-24 Elan Med Tech Intradermal delivery device
DE59505328D1 (de) * 1994-12-09 1999-04-15 Novartis Ag Transdermales system
EP0858285A4 (de) * 1995-08-29 2000-05-17 Spectrx Inc Mikroporation der menschlichen haut zur arzneimittelabgabe und überwachungsanwendungen
DE69722414T2 (de) * 1996-07-03 2004-05-19 Altea Therapeutics Corp. Mehrfache mechanische mikroperforierung von haut oder schleimhäuten

Also Published As

Publication number Publication date
DE69718495D1 (de) 2003-02-20
CA2265906C (en) 2003-11-11
US5983136A (en) 1999-11-09
JP2007325955A (ja) 2007-12-20
JP2002510982A (ja) 2002-04-09
CA2265906A1 (en) 1998-03-26
WO1998011937A1 (en) 1998-03-26
JP4054381B2 (ja) 2008-02-27
ATE231015T1 (de) 2003-02-15
EP0934093B1 (de) 2003-01-15
EP0934093A1 (de) 1999-08-11

Similar Documents

Publication Publication Date Title
DE69718495D1 (de) System zur medikamentenabgabe durch transport
Kligman et al. Preparation of isolated sheets of human stratum corneum
GB2335603A (en) Skin enhancement using laser light
MX9300607A (es) Aparato y metodo para tratamiento intersticial.
MXPA02011416A (es) Combinacion de submucosa del intestino delgado y vendaje a vacio, y su metodo de utilizacion.
BRPI0416822A (pt) método e sistema de liberação de vacina transdérmica com ultra-som
AR008242A1 (es) Dispositivo para atravesar el estrato corneo de una superficie corporal
EP1314400A3 (de) Mikroporation von Gewebe zur Verabreichung von bioaktiven Substanzen
DK0688189T3 (da) Sårbehandling under anvendelse af nedsat tryk
MXPA02010984A (es) Vendaje para heridas abdominales.
DE60113557D1 (de) Mikrostrukturen zur kutanen verabreichung eines mittels auf die haut
ATE413860T1 (de) Bausatz, vorrichtung und verfahren zur gesteuerten abgabe eines oxidationsmittels in die haut
CA2316534A1 (en) Method and device for abrading skin
DE60314157D1 (de) Verfahren und vorrichtung zur epidermischen verabreichung einer substanz
TW200517156A (en) Pretreatment method and system for enhancing transdermal drug delivery
DK662887A (da) Fladeformigt terapeutisk system, fremgangsmaade til fremstilling deraf og anvendelse deraf
DE69722414D1 (de) Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
ATE48762T1 (de) System zur verabreichung von substanzen durch die haut.
DE3878909D1 (de) Vorrichtung und verfahren zur herstellung eines komposithautersatzes.
TW200621316A (en) Apparatus and method for transdermal delivery of vascular endothelial growth factors
MX9710027A (es) Proceso para la identificacion de personas.
US20050100571A1 (en) Method and device to treat skin affected by a corn
Corps Wound contracture in the hooded rat in relation to skin tension lines and depth of injury
WO2019100902A1 (zh) 一种透皮促渗皮肤美容方法
US20060089610A1 (en) Skin-peeling pad

Legal Events

Date Code Title Description
8364 No opposition during term of opposition