DE69717263D1 - Zubereitung mit verzögerter freisetzung und deren herstellung - Google Patents
Zubereitung mit verzögerter freisetzung und deren herstellungInfo
- Publication number
- DE69717263D1 DE69717263D1 DE69717263T DE69717263T DE69717263D1 DE 69717263 D1 DE69717263 D1 DE 69717263D1 DE 69717263 T DE69717263 T DE 69717263T DE 69717263 T DE69717263 T DE 69717263T DE 69717263 D1 DE69717263 D1 DE 69717263D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- preparation
- delayed release
- sustained
- dispersing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7301696 | 1996-03-28 | ||
PCT/JP1997/001041 WO1997035563A2 (en) | 1996-03-28 | 1997-03-27 | Sustained-release preparation and its production |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69717263D1 true DE69717263D1 (de) | 2003-01-02 |
DE69717263T2 DE69717263T2 (de) | 2003-07-24 |
Family
ID=13506129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69717263T Expired - Lifetime DE69717263T2 (de) | 1996-03-28 | 1997-03-27 | Zubereitung mit verzögerter freisetzung und deren herstellung |
Country Status (8)
Country | Link |
---|---|
US (2) | US6190702B1 (de) |
EP (1) | EP0889722B1 (de) |
AT (1) | ATE227980T1 (de) |
AU (1) | AU2043297A (de) |
CA (1) | CA2241322C (de) |
DE (1) | DE69717263T2 (de) |
DK (1) | DK0889722T3 (de) |
WO (1) | WO1997035563A2 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE192334T1 (de) | 1995-11-09 | 2000-05-15 | Microbiological Res Authority | Mikroverkapselte dna zur impfung und gentherapie |
US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
US6287587B2 (en) | 1997-07-15 | 2001-09-11 | Takeda Chemical Industries, Ltd. | Process for producing sustained-release preparation by in-water drying |
NZ505651A (en) | 1998-01-16 | 2003-08-29 | Takeda Chemical Industries Ltd | Sustained release composition comprising biologically active substance, hydroxynaphthoic acid and biodegradable polymer |
ATE235231T1 (de) * | 1998-01-21 | 2003-04-15 | Takeda Chemical Industries Ltd | Verfahren zur gerfriertrocknung von präparaten mit verzörgerter wirkstoffabgabe |
BR9908936A (pt) | 1998-03-20 | 2005-10-25 | Takeda Chemical Industries Ltd | Processos para produzir uma preparação de liberação sustentada, e para produzir um pó de polipeptìdeo fisiologicamente ativo, preparação de liberação sustentada, pó de polipeptìdeo fisiologicamente ativo, e, usos do pó polipeptìdeo fisiologicamente ativo, e de um solvente orgânico miscìvel em água e/ou um sal volátil |
GB9810236D0 (en) * | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
US7029700B2 (en) | 2000-01-14 | 2006-04-18 | Brown University Research Foundation | Micronized freeze-dried particles |
WO2001051032A2 (en) * | 2000-01-14 | 2001-07-19 | Brown University Research Foundation | Micronized freeze-dried particles |
CA2402191C (en) | 2000-03-24 | 2012-03-13 | Genentech, Inc. | Use of insulin for the treatment of cartilagenous disorders |
US20080233165A1 (en) * | 2000-08-07 | 2008-09-25 | Biolok International, Inc. | Time release calcium sulfate and growth factor matrix for bone augmentation |
US7488761B2 (en) * | 2000-08-07 | 2009-02-10 | Orthogen Llc | Polymer containing calcium sulfate particles for bone augmentation |
US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
CA2680475A1 (en) * | 2000-12-28 | 2002-07-11 | Shigeyuki Takada | Sustained-release preparation |
JP2002265383A (ja) * | 2001-03-14 | 2002-09-18 | Mitsubishi Pharma Corp | インターフェロンα注射用液状製剤 |
WO2002078673A1 (fr) * | 2001-03-29 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Procede de production d'un medicament sous forme de granules fins |
US20040126900A1 (en) * | 2001-04-13 | 2004-07-01 | Barry Stephen E | High affinity peptide- containing nanoparticles |
US6887897B2 (en) | 2001-07-31 | 2005-05-03 | Mission Pharmacal Company | Calcium glutarate supplement and phosphorus binder |
KR100994658B1 (ko) * | 2001-12-26 | 2010-11-16 | 다케다 야쿠힌 고교 가부시키가이샤 | 신규 마이크로스피어 및 이들의 제조 방법 |
PT2301965E (pt) | 2002-10-16 | 2015-05-20 | Purdue Pharma Lp | Anticorpos que se ligam a ca 125/0722p associado a células e métodos para a sua utilização |
AU2003277446A1 (en) | 2002-10-17 | 2004-05-04 | Alkermes Controlled Therapeutics, Inc. Ii | Microencapsulation and sustained release of biologically active polypeptides |
US7456254B2 (en) * | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
KR101040415B1 (ko) * | 2004-04-15 | 2011-06-09 | 알케르메스,인코포레이티드 | 중합체 기재 지속적 방출 방법 |
US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
US20060110423A1 (en) * | 2004-04-15 | 2006-05-25 | Wright Steven G | Polymer-based sustained release device |
US8075910B2 (en) * | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
DE502006005846D1 (de) * | 2005-04-13 | 2010-02-25 | Abbott Gmbh & Co Kg | Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung |
DE102005017777A1 (de) * | 2005-04-13 | 2006-10-19 | Pharmasol Gmbh | Verfahren zur schonenden Herstellung von hochfeinen Partikelsuspensionen |
WO2008021133A2 (en) | 2006-08-09 | 2008-02-21 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
EP2131815A4 (de) * | 2007-03-22 | 2012-11-07 | Alkermes Inc | Koazervierungsverfahren |
NZ580447A (en) | 2007-04-23 | 2011-06-30 | Intarcia Therapeutics Inc | Suspension formulations of insulinotropic peptides and uses thereof |
US20080317865A1 (en) * | 2007-06-20 | 2008-12-25 | Alkermes, Inc. | Quench liquids and washing systems for production of microparticles |
EP2044934A1 (de) * | 2007-10-01 | 2009-04-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Dispersion von Poloxamer-Proteinpartikeln, Herstellungsmethoden und Verwendung davon |
US8343140B2 (en) | 2008-02-13 | 2013-01-01 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
CN104248623B (zh) * | 2008-09-04 | 2020-04-03 | 安米林药品有限责任公司 | 使用非水性载体的持续释放制剂 |
PT2343982T (pt) | 2008-09-17 | 2017-07-04 | Chiasma Inc | Composições farmacêuticas e métodos de administração associados |
NZ624569A (en) | 2009-09-28 | 2016-01-29 | Intarcia Therapeutics Inc | Rapid establishment and/or termination of substantial steady-state drug delivery |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
AU2016215350B2 (en) | 2015-02-03 | 2021-11-25 | Amryt Endo, Inc. | Method of treating diseases |
MX2017015504A (es) | 2015-06-03 | 2018-05-15 | Intarcia Therapeutics Inc | Sistemas de colocacion y remoción de implante. |
SG11201810102SA (en) | 2016-05-16 | 2018-12-28 | Intarcia Therapeutics Inc | Glucagon-receptor selective polypeptides and methods of use thereof |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
IL307966A (en) | 2017-01-03 | 2023-12-01 | Intarcia Therapeutics Inc | Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
EP3838268B1 (de) * | 2017-02-24 | 2023-05-10 | The Regents of the University of California | Partikeltropfenstrukturen und verfahren zur herstellung und verwendung davon |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5385738A (en) | 1983-10-14 | 1995-01-31 | Sumitomo Pharmaceuticals Company, Ltd. | Sustained-release injection |
US4774091A (en) | 1983-10-14 | 1988-09-27 | Sumitomo Pharmaceuticals Company, Ltd. | Long-term sustained-release preparation |
US4963367A (en) | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
US4962091A (en) | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
JP3116311B2 (ja) | 1990-06-13 | 2000-12-11 | エーザイ株式会社 | マイクロスフィアの製法 |
NO302481B1 (no) * | 1990-10-16 | 1998-03-09 | Takeda Chemical Industries Ltd | Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring |
US5288502A (en) * | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
EP1013270A3 (de) | 1992-12-02 | 2001-03-28 | Alkermes Controlled Therapeutics, Inc. | Wachstumhormon enthaltende Mikrosphaeren mit kontrollierter Freisetzung |
ES2153418T3 (es) | 1993-02-23 | 2001-03-01 | Genentech Inc | Estabilizacion de polipeptidos tratados con solventes organicos por medio de excipientes. |
NZ260909A (en) * | 1993-07-05 | 1995-04-27 | Takeda Chemical Industries Ltd | Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution |
AU8017494A (en) * | 1993-10-22 | 1995-05-08 | Genentech Inc. | Method for preparing microspheres comprising a fluidized bed drying step |
US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
TW448055B (en) * | 1995-09-04 | 2001-08-01 | Takeda Chemical Industries Ltd | Method of production of sustained-release preparation |
EP0765660A3 (de) * | 1995-09-28 | 1998-09-23 | Takeda Chemical Industries, Ltd. | Mikrokapseln enthaltend 2-Piperazinon-1-essigsäure Verbindungen |
-
1997
- 1997-03-27 AU AU20432/97A patent/AU2043297A/en not_active Abandoned
- 1997-03-27 CA CA002241322A patent/CA2241322C/en not_active Expired - Fee Related
- 1997-03-27 AT AT97908520T patent/ATE227980T1/de not_active IP Right Cessation
- 1997-03-27 DE DE69717263T patent/DE69717263T2/de not_active Expired - Lifetime
- 1997-03-27 WO PCT/JP1997/001041 patent/WO1997035563A2/en active IP Right Grant
- 1997-03-27 US US08/849,172 patent/US6190702B1/en not_active Expired - Lifetime
- 1997-03-27 DK DK97908520T patent/DK0889722T3/da active
- 1997-03-27 EP EP97908520A patent/EP0889722B1/de not_active Expired - Lifetime
-
2001
- 2001-01-19 US US09/764,052 patent/US20010006678A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2043297A (en) | 1997-10-17 |
CA2241322A1 (en) | 1997-10-02 |
EP0889722A2 (de) | 1999-01-13 |
US20010006678A1 (en) | 2001-07-05 |
DE69717263T2 (de) | 2003-07-24 |
ATE227980T1 (de) | 2002-12-15 |
WO1997035563A2 (en) | 1997-10-02 |
DK0889722T3 (da) | 2003-02-10 |
CA2241322C (en) | 2009-01-13 |
US6190702B1 (en) | 2001-02-20 |
EP0889722B1 (de) | 2002-11-20 |
WO1997035563A3 (en) | 1997-11-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP |