DE69717263D1 - Zubereitung mit verzögerter freisetzung und deren herstellung - Google Patents

Zubereitung mit verzögerter freisetzung und deren herstellung

Info

Publication number
DE69717263D1
DE69717263D1 DE69717263T DE69717263T DE69717263D1 DE 69717263 D1 DE69717263 D1 DE 69717263D1 DE 69717263 T DE69717263 T DE 69717263T DE 69717263 T DE69717263 T DE 69717263T DE 69717263 D1 DE69717263 D1 DE 69717263D1
Authority
DE
Germany
Prior art keywords
production
preparation
delayed release
sustained
dispersing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69717263T
Other languages
English (en)
Other versions
DE69717263T2 (de
Inventor
Shigeyuki Takada
Tomofumi Kurokawa
Susumu Iwasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69717263D1 publication Critical patent/DE69717263D1/de
Publication of DE69717263T2 publication Critical patent/DE69717263T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
DE69717263T 1996-03-28 1997-03-27 Zubereitung mit verzögerter freisetzung und deren herstellung Expired - Lifetime DE69717263T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7301696 1996-03-28
PCT/JP1997/001041 WO1997035563A2 (en) 1996-03-28 1997-03-27 Sustained-release preparation and its production

Publications (2)

Publication Number Publication Date
DE69717263D1 true DE69717263D1 (de) 2003-01-02
DE69717263T2 DE69717263T2 (de) 2003-07-24

Family

ID=13506129

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69717263T Expired - Lifetime DE69717263T2 (de) 1996-03-28 1997-03-27 Zubereitung mit verzögerter freisetzung und deren herstellung

Country Status (8)

Country Link
US (2) US6190702B1 (de)
EP (1) EP0889722B1 (de)
AT (1) ATE227980T1 (de)
AU (1) AU2043297A (de)
CA (1) CA2241322C (de)
DE (1) DE69717263T2 (de)
DK (1) DK0889722T3 (de)
WO (1) WO1997035563A2 (de)

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US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
US6287587B2 (en) 1997-07-15 2001-09-11 Takeda Chemical Industries, Ltd. Process for producing sustained-release preparation by in-water drying
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ATE235231T1 (de) * 1998-01-21 2003-04-15 Takeda Chemical Industries Ltd Verfahren zur gerfriertrocknung von präparaten mit verzörgerter wirkstoffabgabe
BR9908936A (pt) 1998-03-20 2005-10-25 Takeda Chemical Industries Ltd Processos para produzir uma preparação de liberação sustentada, e para produzir um pó de polipeptìdeo fisiologicamente ativo, preparação de liberação sustentada, pó de polipeptìdeo fisiologicamente ativo, e, usos do pó polipeptìdeo fisiologicamente ativo, e de um solvente orgânico miscìvel em água e/ou um sal volátil
GB9810236D0 (en) * 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US7029700B2 (en) 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
WO2001051032A2 (en) * 2000-01-14 2001-07-19 Brown University Research Foundation Micronized freeze-dried particles
CA2402191C (en) 2000-03-24 2012-03-13 Genentech, Inc. Use of insulin for the treatment of cartilagenous disorders
US20080233165A1 (en) * 2000-08-07 2008-09-25 Biolok International, Inc. Time release calcium sulfate and growth factor matrix for bone augmentation
US7488761B2 (en) * 2000-08-07 2009-02-10 Orthogen Llc Polymer containing calcium sulfate particles for bone augmentation
US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
CA2680475A1 (en) * 2000-12-28 2002-07-11 Shigeyuki Takada Sustained-release preparation
JP2002265383A (ja) * 2001-03-14 2002-09-18 Mitsubishi Pharma Corp インターフェロンα注射用液状製剤
WO2002078673A1 (fr) * 2001-03-29 2002-10-10 Takeda Chemical Industries, Ltd. Procede de production d'un medicament sous forme de granules fins
US20040126900A1 (en) * 2001-04-13 2004-07-01 Barry Stephen E High affinity peptide- containing nanoparticles
US6887897B2 (en) 2001-07-31 2005-05-03 Mission Pharmacal Company Calcium glutarate supplement and phosphorus binder
KR100994658B1 (ko) * 2001-12-26 2010-11-16 다케다 야쿠힌 고교 가부시키가이샤 신규 마이크로스피어 및 이들의 제조 방법
PT2301965E (pt) 2002-10-16 2015-05-20 Purdue Pharma Lp Anticorpos que se ligam a ca 125/0722p associado a células e métodos para a sua utilização
AU2003277446A1 (en) 2002-10-17 2004-05-04 Alkermes Controlled Therapeutics, Inc. Ii Microencapsulation and sustained release of biologically active polypeptides
US7456254B2 (en) * 2004-04-15 2008-11-25 Alkermes, Inc. Polymer-based sustained release device
KR101040415B1 (ko) * 2004-04-15 2011-06-09 알케르메스,인코포레이티드 중합체 기재 지속적 방출 방법
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
US20060110423A1 (en) * 2004-04-15 2006-05-25 Wright Steven G Polymer-based sustained release device
US8075910B2 (en) * 2004-05-20 2011-12-13 Pbm Pharmaceuticals, Inc. Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
DE502006005846D1 (de) * 2005-04-13 2010-02-25 Abbott Gmbh & Co Kg Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung
DE102005017777A1 (de) * 2005-04-13 2006-10-19 Pharmasol Gmbh Verfahren zur schonenden Herstellung von hochfeinen Partikelsuspensionen
WO2008021133A2 (en) 2006-08-09 2008-02-21 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
EP2131815A4 (de) * 2007-03-22 2012-11-07 Alkermes Inc Koazervierungsverfahren
NZ580447A (en) 2007-04-23 2011-06-30 Intarcia Therapeutics Inc Suspension formulations of insulinotropic peptides and uses thereof
US20080317865A1 (en) * 2007-06-20 2008-12-25 Alkermes, Inc. Quench liquids and washing systems for production of microparticles
EP2044934A1 (de) * 2007-10-01 2009-04-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Dispersion von Poloxamer-Proteinpartikeln, Herstellungsmethoden und Verwendung davon
US8343140B2 (en) 2008-02-13 2013-01-01 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
CN104248623B (zh) * 2008-09-04 2020-04-03 安米林药品有限责任公司 使用非水性载体的持续释放制剂
PT2343982T (pt) 2008-09-17 2017-07-04 Chiasma Inc Composições farmacêuticas e métodos de administração associados
NZ624569A (en) 2009-09-28 2016-01-29 Intarcia Therapeutics Inc Rapid establishment and/or termination of substantial steady-state drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
AU2016215350B2 (en) 2015-02-03 2021-11-25 Amryt Endo, Inc. Method of treating diseases
MX2017015504A (es) 2015-06-03 2018-05-15 Intarcia Therapeutics Inc Sistemas de colocacion y remoción de implante.
SG11201810102SA (en) 2016-05-16 2018-12-28 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
IL307966A (en) 2017-01-03 2023-12-01 Intarcia Therapeutics Inc Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug
EP3838268B1 (de) * 2017-02-24 2023-05-10 The Regents of the University of California Partikeltropfenstrukturen und verfahren zur herstellung und verwendung davon
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

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US5385738A (en) 1983-10-14 1995-01-31 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release injection
US4774091A (en) 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4962091A (en) 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
JP3116311B2 (ja) 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
NO302481B1 (no) * 1990-10-16 1998-03-09 Takeda Chemical Industries Ltd Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring
US5288502A (en) * 1991-10-16 1994-02-22 The University Of Texas System Preparation and uses of multi-phase microspheres
EP1013270A3 (de) 1992-12-02 2001-03-28 Alkermes Controlled Therapeutics, Inc. Wachstumhormon enthaltende Mikrosphaeren mit kontrollierter Freisetzung
ES2153418T3 (es) 1993-02-23 2001-03-01 Genentech Inc Estabilizacion de polipeptidos tratados con solventes organicos por medio de excipientes.
NZ260909A (en) * 1993-07-05 1995-04-27 Takeda Chemical Industries Ltd Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution
AU8017494A (en) * 1993-10-22 1995-05-08 Genentech Inc. Method for preparing microspheres comprising a fluidized bed drying step
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
TW448055B (en) * 1995-09-04 2001-08-01 Takeda Chemical Industries Ltd Method of production of sustained-release preparation
EP0765660A3 (de) * 1995-09-28 1998-09-23 Takeda Chemical Industries, Ltd. Mikrokapseln enthaltend 2-Piperazinon-1-essigsäure Verbindungen

Also Published As

Publication number Publication date
AU2043297A (en) 1997-10-17
CA2241322A1 (en) 1997-10-02
EP0889722A2 (de) 1999-01-13
US20010006678A1 (en) 2001-07-05
DE69717263T2 (de) 2003-07-24
ATE227980T1 (de) 2002-12-15
WO1997035563A2 (en) 1997-10-02
DK0889722T3 (da) 2003-02-10
CA2241322C (en) 2009-01-13
US6190702B1 (en) 2001-02-20
EP0889722B1 (de) 2002-11-20
WO1997035563A3 (en) 1997-11-20

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP