DE69630460D1 - Flurbiprofenhaltige arzneimittel - Google Patents

Flurbiprofenhaltige arzneimittel

Info

Publication number
DE69630460D1
DE69630460D1 DE69630460T DE69630460T DE69630460D1 DE 69630460 D1 DE69630460 D1 DE 69630460D1 DE 69630460 T DE69630460 T DE 69630460T DE 69630460 T DE69630460 T DE 69630460T DE 69630460 D1 DE69630460 D1 DE 69630460D1
Authority
DE
Germany
Prior art keywords
flurbi
products containing
medicinal products
sugar
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69630460T
Other languages
English (en)
Other versions
DE69630460T2 (de
Inventor
David Michael Barrett
Carl Simon Smith
David Michael Thurgood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of DE69630460D1 publication Critical patent/DE69630460D1/de
Application granted granted Critical
Publication of DE69630460T2 publication Critical patent/DE69630460T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
DE69630460T 1995-11-22 1996-11-21 Flurbiprofenhaltige arzneimittel Expired - Lifetime DE69630460T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9523833 1995-11-22
GBGB9523833.3A GB9523833D0 (en) 1995-11-22 1995-11-22 Medical treatment
PCT/EP1996/005208 WO1997018802A1 (en) 1995-11-22 1996-11-21 Pharmaceutical compositions comprising flurbiprofen

Publications (2)

Publication Number Publication Date
DE69630460D1 true DE69630460D1 (de) 2003-11-27
DE69630460T2 DE69630460T2 (de) 2004-08-19

Family

ID=10784245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69630460T Expired - Lifetime DE69630460T2 (de) 1995-11-22 1996-11-21 Flurbiprofenhaltige arzneimittel

Country Status (21)

Country Link
US (2) US5889057A (de)
EP (1) EP0862424B1 (de)
CN (1) CN1148177C (de)
AT (1) ATE252382T1 (de)
AU (1) AU707749B2 (de)
BG (1) BG64166B1 (de)
CA (1) CA2238271C (de)
CZ (1) CZ289643B6 (de)
DE (1) DE69630460T2 (de)
DK (1) DK0862424T3 (de)
ES (1) ES2208768T3 (de)
GB (1) GB9523833D0 (de)
HU (1) HU225235B1 (de)
IL (1) IL124568A0 (de)
NO (1) NO317287B1 (de)
NZ (1) NZ322933A (de)
PT (1) PT862424E (de)
RU (1) RU2203655C2 (de)
SK (1) SK284092B6 (de)
UA (1) UA46807C2 (de)
WO (1) WO1997018802A1 (de)

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AU8107998A (en) * 1997-05-22 1998-12-11 Boots Company Plc, The Pharmaceutical compositions
GB9710521D0 (en) * 1997-05-22 1997-07-16 Boots Co Plc Process
AU7916798A (en) * 1997-05-22 1998-12-11 Boots Company Plc, The Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat
CA2374003C (en) * 1999-05-17 2008-02-12 Aesgen, Inc. Improved cellular uptake of bioactive agents
CA2406383A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research A.beta.42 lowering agents
US20030100595A1 (en) * 2001-11-13 2003-05-29 Aziz Karim Oral dosage form of a sulfonamide prodrug
US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
EP1572093B1 (de) * 2002-08-01 2013-04-17 Eisai Inc. Vorbeugung von Krebs mit Glutamin
EP1603548A4 (de) * 2003-02-05 2007-10-10 Myriad Genetics Inc Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen
US20040265359A1 (en) * 2003-04-17 2004-12-30 Sacks Gordon S. Oral delivery formulations of L-glutamine
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
US20050252144A1 (en) * 2004-04-29 2005-11-17 Macdonald Robert A Veneers for walls, retaining walls and the like
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CA2618985A1 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
KR20080039876A (ko) * 2005-07-22 2008-05-07 미리어드 제네틱스, 인크. 높은 약물 충진 제형 및 투여형
JP2009514857A (ja) * 2005-11-02 2009-04-09 テイコク ファーマ ユーエスエー インコーポレーテッド 感覚器官的に許容されるイブプロフェン経口投与用製剤、該製剤の製法並びに使用法
US7282224B1 (en) * 2006-06-09 2007-10-16 Guthy-Renker Corporation Pain relief composition
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
US7754234B2 (en) * 2006-07-12 2010-07-13 Jones Thomas L Composition and method of treating a sore throat
US20080107747A1 (en) * 2006-10-23 2008-05-08 Roederer Joy E Pain relief composition
US20090028802A1 (en) * 2007-07-23 2009-01-29 Toru Hibi Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
KR101709904B1 (ko) 2009-05-19 2017-02-23 뉴로덤 엘티디 Dopa 데카르복실라제 억제제의 연속투여용 조성물
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
BR112013011685B1 (pt) * 2010-11-15 2022-03-03 Neuroderm Ltd Composição líquida farmaceuticamente aceitável e emplastro transdérmico
GB201021267D0 (en) * 2010-12-15 2011-01-26 Reckitt Benckiser Healthcare Int Ltd Novel pharmaceutical formulation
ES2715028T3 (es) 2012-06-05 2019-05-31 Neuroderm Ltd Composiciones que comprenden apomorfina y ácidos orgánicos y sus usos
GB201216893D0 (en) 2012-09-21 2012-11-07 Aesica Pharmaceuticals Ltd Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen
PL3116475T3 (pl) 2014-03-13 2021-02-08 Neuroderm Ltd Kompozycje inhibitora dekarboksylazy dopa
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
CN110812331A (zh) * 2018-08-10 2020-02-21 北京普德康利医药科技发展有限公司 一种氟比洛芬咽部滞留颗粒
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
CN115536525B (zh) * 2022-09-23 2024-02-23 南京知和医药科技有限公司 一种s-(+)-氟比洛芬盐及其制备方法、药物组合物和用途

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US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
JPH0647532B2 (ja) * 1983-08-31 1994-06-22 ジ アツプジヨン カンパニ− 歯槽骨吸収の治療
EP0228223A3 (de) * 1985-12-16 1987-09-09 Cilag AG Nichtirritierende Suprofenlösungen
JPH02500189A (ja) * 1986-10-22 1990-01-25 ジ・アップジョン・カンパニー イブプロフェンまたはフルルビプロフェンを用いる歯肉炎の治療
JPS63156715A (ja) * 1986-12-19 1988-06-29 Teisan Seiyaku Kk 即効性の徐放化製剤
JP2540581B2 (ja) * 1988-02-04 1996-10-02 三省製薬株式会社 外用剤
US4931473A (en) * 1989-02-15 1990-06-05 Richardson-Vicks Inc. Anesthetic oral compositions
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
CA2064722C (en) * 1989-08-17 2001-05-08 William J. Wechter Buccal composition containing s(+) flurbiprofen or ketoprofen
JP2738092B2 (ja) * 1989-11-17 1998-04-08 ライオン株式会社 口腔用組成物
JPH0426618A (ja) * 1990-05-21 1992-01-29 Japan Tobacco Inc トローチ剤
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
WO1994013280A1 (en) * 1992-12-04 1994-06-23 Mayor Pharmaceutical Laboratories, Inc. Sprayable analgesic composition and method of use
CA2151912A1 (en) * 1992-12-21 1994-07-07 Richard Wilfred D'souza Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
ES2211916T3 (es) * 1994-09-02 2004-07-16 Virginia Commonwealth University Composicion para aliviar dolor, que contiene un analgesico no narcortico y un potenciador de analgesia.
US5567733B1 (en) * 1995-04-27 1999-08-24 Jon G Dishler Irritation relief using nonsteroidal anti-inflammatory compounds
EP0837862A1 (de) * 1995-07-05 1998-04-29 The Procter & Gamble Company Ein wärmegefühl gebende verbindungen
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AU2190697A (en) * 1996-04-12 1997-11-07 Flemington Pharmaceutical Corporation Buccal polar spray or capsule

Also Published As

Publication number Publication date
BG102526A (en) 1999-02-26
CN1148177C (zh) 2004-05-05
DE69630460T2 (de) 2004-08-19
NO982294D0 (no) 1998-05-20
NO317287B1 (no) 2004-10-04
EP0862424B1 (de) 2003-10-22
WO1997018802A1 (en) 1997-05-29
PT862424E (pt) 2004-02-27
HU225235B1 (en) 2006-08-28
RU2203655C2 (ru) 2003-05-10
AU707749B2 (en) 1999-07-22
CA2238271C (en) 2008-08-12
ATE252382T1 (de) 2003-11-15
DK0862424T3 (da) 2003-12-29
NZ322933A (en) 2000-02-28
CN1207677A (zh) 1999-02-10
SK284092B6 (sk) 2004-09-08
AU2611997A (en) 1997-06-11
CZ156598A3 (cs) 1998-08-12
US6166083A (en) 2000-12-26
HUP0000180A3 (en) 2001-10-29
BG64166B1 (bg) 2004-03-31
IL124568A0 (en) 1998-12-06
HUP0000180A2 (hu) 2000-08-28
SK66598A3 (en) 1998-12-02
CA2238271A1 (en) 1997-05-29
GB9523833D0 (en) 1996-01-24
CZ289643B6 (cs) 2002-03-13
UA46807C2 (uk) 2002-06-17
US5889057A (en) 1999-03-30
EP0862424A1 (de) 1998-09-09
ES2208768T3 (es) 2004-06-16
NO982294L (no) 1998-07-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, GB