US5547839A
(en)
*
|
1989-06-07 |
1996-08-20 |
Affymax Technologies N.V. |
Sequencing of surface immobilized polymers utilizing microflourescence detection
|
US6436635B1
(en)
*
|
1992-11-06 |
2002-08-20 |
Boston University |
Solid phase sequencing of double-stranded nucleic acids
|
US5795714A
(en)
*
|
1992-11-06 |
1998-08-18 |
Trustees Of Boston University |
Method for replicating an array of nucleic acid probes
|
US6194144B1
(en)
|
1993-01-07 |
2001-02-27 |
Sequenom, Inc. |
DNA sequencing by mass spectrometry
|
US5605798A
(en)
|
1993-01-07 |
1997-02-25 |
Sequenom, Inc. |
DNA diagnostic based on mass spectrometry
|
EP1262564A3
(de)
|
1993-01-07 |
2004-03-31 |
Sequenom, Inc. |
Dns-Sequenzierung durch Massenspektrometrie
|
US6225059B1
(en)
|
1993-11-01 |
2001-05-01 |
Nanogen, Inc. |
Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics
|
US6331274B1
(en)
|
1993-11-01 |
2001-12-18 |
Nanogen, Inc. |
Advanced active circuits and devices for molecular biological analysis and diagnostics
|
US6207373B1
(en)
|
1998-02-25 |
2001-03-27 |
Nanogen, Inc. |
Methods for determining nature of repeat units in DNA
|
US6379897B1
(en)
|
2000-11-09 |
2002-04-30 |
Nanogen, Inc. |
Methods for gene expression monitoring on electronic microarrays
|
US7803529B1
(en)
|
1995-04-11 |
2010-09-28 |
Sequenom, Inc. |
Solid phase sequencing of biopolymers
|
DE19525632C2
(de)
*
|
1995-07-14 |
1997-07-17 |
Bag Biolog Analysensystem Gmbh |
Sequenzspezifisches Nukleinsäurenachweisverfahren und Reagenz-System zu dessen Durchführung
|
US6146854A
(en)
*
|
1995-08-31 |
2000-11-14 |
Sequenom, Inc. |
Filtration processes, kits and devices for isolating plasmids
|
EP0876510B1
(de)
*
|
1995-12-22 |
2008-05-07 |
Dade Behring Marburg GmbH |
Homogene vervielfältigung und nachweis von nukleinsäuren
|
ATE229081T1
(de)
*
|
1996-01-26 |
2002-12-15 |
Abbott Lab |
Verfahren zur analyse von nukleinsäure- wiederholungssequenzen
|
US5770370A
(en)
*
|
1996-06-14 |
1998-06-23 |
David Sarnoff Research Center, Inc. |
Nuclease protection assays
|
US5777324A
(en)
|
1996-09-19 |
1998-07-07 |
Sequenom, Inc. |
Method and apparatus for maldi analysis
|
US6133436A
(en)
|
1996-11-06 |
2000-10-17 |
Sequenom, Inc. |
Beads bound to a solid support and to nucleic acids
|
US6083701A
(en)
*
|
1996-11-29 |
2000-07-04 |
Amersham Pharmacia Biotech Uk Limited |
Method for determining tandem repeat sequence length
|
US6482590B1
(en)
|
1996-12-20 |
2002-11-19 |
Aventis Behring Gmbh |
Method for polynucleotide amplification
|
WO1998029736A1
(en)
*
|
1996-12-31 |
1998-07-09 |
Genometrix Incorporated |
Multiplexed molecular analysis apparatus and method
|
EP1591541B1
(de)
*
|
1997-04-01 |
2012-02-15 |
Illumina Cambridge Limited |
Verfahren zur Vervielfältigung von Nukleinsäuren
|
JP4185185B2
(ja)
*
|
1997-05-08 |
2008-11-26 |
征夫 軽部 |
部分二重鎖dnaを利用したdnaの検出方法
|
US20030054378A1
(en)
*
|
1997-05-08 |
2003-03-20 |
Isao Karube |
Method for detecting target nucleotide sequence
|
WO1998053098A1
(de)
*
|
1997-05-21 |
1998-11-26 |
GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) |
Verfahren und kit zur detektion von mutationen in dna's mit hilfe von restriktionsenzymen
|
US6309829B1
(en)
*
|
1997-05-27 |
2001-10-30 |
Pe Corporation (Ny) |
Length determination of nucleic acid repeat sequences by discontinuous primer extension
|
RU2198221C2
(ru)
*
|
1997-07-28 |
2003-02-10 |
Медикал Биосистемз Лтд. |
Способ секвенирования полинуклеотида и устройство для его осуществления
|
WO1999006591A1
(fr)
*
|
1997-07-31 |
1999-02-11 |
The Institute Of Physical And Chemical Research |
Procede de detection de mutation dans une sequence de bases
|
US6326489B1
(en)
|
1997-08-05 |
2001-12-04 |
Howard Hughes Medical Institute |
Surface-bound, bimolecular, double-stranded DNA arrays
|
US6207370B1
(en)
|
1997-09-02 |
2001-03-27 |
Sequenom, Inc. |
Diagnostics based on mass spectrometric detection of translated target polypeptides
|
US6485944B1
(en)
|
1997-10-10 |
2002-11-26 |
President And Fellows Of Harvard College |
Replica amplification of nucleic acid arrays
|
US6511803B1
(en)
|
1997-10-10 |
2003-01-28 |
President And Fellows Of Harvard College |
Replica amplification of nucleic acid arrays
|
CA2305449A1
(en)
|
1997-10-10 |
1999-04-22 |
President & Fellows Of Harvard College |
Replica amplification of nucleic acid arrays
|
WO1999019510A1
(en)
*
|
1997-10-10 |
1999-04-22 |
President And Fellows Of Harvard College |
Surface-bound, double-stranded dna protein arrays
|
AU1623899A
(en)
*
|
1997-12-04 |
1999-06-16 |
Packard Bioscience Company |
Methods of using probes for analyzing polynucleotide sequence
|
US20030096232A1
(en)
*
|
1997-12-19 |
2003-05-22 |
Kris Richard M. |
High throughput assay system
|
US20100105572A1
(en)
*
|
1997-12-19 |
2010-04-29 |
Kris Richard M |
High throughput assay system
|
US20030039967A1
(en)
*
|
1997-12-19 |
2003-02-27 |
Kris Richard M. |
High throughput assay system using mass spectrometry
|
US6087102A
(en)
*
|
1998-01-07 |
2000-07-11 |
Clontech Laboratories, Inc. |
Polymeric arrays and methods for their use in binding assays
|
WO1999036571A2
(en)
*
|
1998-01-13 |
1999-07-22 |
Biochip Technologies Gmbh |
Method for the detection or nucleic acid of nucleic acid sequences
|
US6787308B2
(en)
|
1998-07-30 |
2004-09-07 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
AR021833A1
(es)
|
1998-09-30 |
2002-08-07 |
Applied Research Systems |
Metodos de amplificacion y secuenciacion de acido nucleico
|
AU1724000A
(en)
|
1998-11-12 |
2000-05-29 |
Nyxis, Inc. |
Diagnostic assay for cancer
|
US6287773B1
(en)
*
|
1999-05-19 |
2001-09-11 |
Hoeschst-Ariad Genomics Center |
Profile searching in nucleic acid sequences using the fast fourier transformation
|
ATE323113T1
(de)
|
1999-07-02 |
2006-04-15 |
Symyx Technologies Inc |
Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen
|
US6342362B1
(en)
*
|
1999-08-05 |
2002-01-29 |
Daniel S. Mytelka |
Methods and compositions for the purification of proteins or other macromolecules
|
GB9923644D0
(en)
|
1999-10-06 |
1999-12-08 |
Medical Biosystems Ltd |
DNA sequencing
|
US6908736B1
(en)
|
1999-10-06 |
2005-06-21 |
Medical Biosystems, Ltd. |
DNA sequencing method
|
US7875442B2
(en)
*
|
2000-03-24 |
2011-01-25 |
Eppendorf Array Technologies |
Identification and quantification of a plurality of biological (micro)organisms or their components
|
US7829313B2
(en)
*
|
2000-03-24 |
2010-11-09 |
Eppendorf Array Technologies |
Identification and quantification of a plurality of biological (micro)organisms or their components
|
JP4589480B2
(ja)
*
|
2000-03-30 |
2010-12-01 |
オリンパス株式会社 |
反復配列の多型を分析する方法
|
EP1158058A1
(de)
*
|
2000-05-19 |
2001-11-28 |
Centre National De La Recherche Scientifique |
Zusammensetzungen und Verfahren geeignet für Nukleinsäureanalyse
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
AU2001285219A1
(en)
*
|
2000-08-24 |
2002-03-04 |
Aviva Biosciences Corporation |
Methods and compositions for identifying nucleic acid molecules using nucleolytic activities and hybridization
|
US20040185464A1
(en)
*
|
2000-09-15 |
2004-09-23 |
Kris Richard M. |
High throughput assay system
|
KR100649342B1
(ko)
|
2000-10-30 |
2006-11-27 |
시쿼넘, 인코포레이티드 |
기판 상으로 서브마이크로리터 볼륨들을 전달하기 위한 방법 및 장치
|
AR031640A1
(es)
*
|
2000-12-08 |
2003-09-24 |
Applied Research Systems |
Amplificacion isotermica de acidos nucleicos en un soporte solido
|
AU2002246978A1
(en)
*
|
2001-01-10 |
2002-07-24 |
Symyx Technologies, Inc. |
Polymer brushes for immobilizing molecules to a surface
|
US7202392B2
(en)
*
|
2001-01-31 |
2007-04-10 |
The General Hospital Corporation |
In vivo screening array
|
EP1430150B1
(de)
|
2001-09-24 |
2015-08-19 |
One Lambda, Inc. |
Diagnostisches sondennachweissystem
|
AU2003213107A1
(en)
|
2002-02-15 |
2003-09-09 |
Exact Sciences Corporation |
Methods for analysis of molecular events
|
US6713262B2
(en)
*
|
2002-06-25 |
2004-03-30 |
Agilent Technologies, Inc. |
Methods and compositions for high throughput identification of protein/nucleic acid binding pairs
|
AU2003298733B2
(en)
*
|
2002-11-27 |
2009-06-18 |
Agena Bioscience, Inc. |
Fragmentation-based methods and systems for sequence variation detection and discovery
|
CA2523490A1
(en)
*
|
2003-04-25 |
2004-11-11 |
Sequenom, Inc. |
Fragmentation-based methods and systems for de novo sequencing
|
US9394565B2
(en)
*
|
2003-09-05 |
2016-07-19 |
Agena Bioscience, Inc. |
Allele-specific sequence variation analysis
|
US7964344B2
(en)
*
|
2003-09-17 |
2011-06-21 |
Canon Kabushiki Kaisha |
Stable hybrid
|
JP4339062B2
(ja)
*
|
2003-09-30 |
2009-10-07 |
富士フイルム株式会社 |
ミスマッチ領域検出方法
|
JP4801445B2
(ja)
|
2003-12-24 |
2011-10-26 |
信一郎 礒部 |
生体分子の検出方法及びそれに用いる標識色素並びに標識キット
|
US20050191636A1
(en)
*
|
2004-03-01 |
2005-09-01 |
Biocept, Inc. |
Detection of STRP, such as fragile X syndrome
|
CN101233240A
(zh)
*
|
2004-03-26 |
2008-07-30 |
斯昆诺有限公司 |
与质量分析结合的甲基化特异性扩增产物的碱基特异性切割
|
US20080241827A1
(en)
*
|
2004-05-10 |
2008-10-02 |
Exact Sciences Corporation |
Methods For Detecting A Mutant Nucleic Acid
|
US20060008823A1
(en)
*
|
2004-05-12 |
2006-01-12 |
Kemp Jennifer T |
DNA profiling and SNP detection utilizing microarrays
|
BR122016013290B1
(pt)
*
|
2004-05-13 |
2021-04-20 |
Anita Goel |
dispositivo para amplificação de moléculas de ácido nucleico, dispositivo microfluídico para aplicação de tensão às moléculas de ácido nucléico e kits para processamento de molécula de ácido nucléico
|
WO2006026654A2
(en)
*
|
2004-08-27 |
2006-03-09 |
Exact Sciences Corporation |
Method for detecting a recombinant event
|
JP2008512129A
(ja)
*
|
2004-09-10 |
2008-04-24 |
セクエノム,インコーポレイティド |
核酸の広範囲配列分析法
|
US7501253B2
(en)
*
|
2004-09-21 |
2009-03-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
DNA fingerprinting using a branch migration assay
|
US7238486B2
(en)
*
|
2004-09-21 |
2007-07-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
DNA fingerprinting using a branch migration assay
|
WO2006047787A2
(en)
|
2004-10-27 |
2006-05-04 |
Exact Sciences Corporation |
Method for monitoring disease progression or recurrence
|
US9777314B2
(en)
*
|
2005-04-21 |
2017-10-03 |
Esoterix Genetic Laboratories, Llc |
Analysis of heterogeneous nucleic acid samples
|
GB0522310D0
(en)
|
2005-11-01 |
2005-12-07 |
Solexa Ltd |
Methods of preparing libraries of template polynucleotides
|
GB0524069D0
(en)
*
|
2005-11-25 |
2006-01-04 |
Solexa Ltd |
Preparation of templates for solid phase amplification
|
EP1963528A4
(de)
*
|
2005-12-20 |
2009-11-25 |
Ming-Sheng Lee |
Vorrichtung, verfahren und produkte zur erkennung einer genetischen mutation
|
US20080009420A1
(en)
*
|
2006-03-17 |
2008-01-10 |
Schroth Gary P |
Isothermal methods for creating clonal single molecule arrays
|
EP2016415B1
(de)
|
2006-04-21 |
2013-08-14 |
Nanobiosym, Inc. |
Einzelmolekülplattform für wirkstoffentdeckung: verfahren für wirkstoffentdeckung, einschliesslich der entdeckung von krebsmitteln und viruziden
|
US20080076121A1
(en)
*
|
2006-09-22 |
2008-03-27 |
Paul Kenneth Wolber |
Microarray nuclease protection assay
|
TWI412593B
(zh)
*
|
2006-12-20 |
2013-10-21 |
Ming-Sheng Lee |
基因變異檢體的檢測方法及用具組
|
US7888069B2
(en)
*
|
2006-12-22 |
2011-02-15 |
Dow Agrosciences Llc |
Plant-made west nile virus (WNV) vaccines, vectors and plant codon optimized sequences
|
EP2121983A2
(de)
|
2007-02-02 |
2009-11-25 |
Illumina Cambridge Limited |
Verfahren zur kennzeichnung von proben und sequenzierung mehrerer nukleotidmatrizen
|
US7947446B2
(en)
*
|
2007-05-29 |
2011-05-24 |
Ming-Sheng Lee |
High throughput mutation screening methods and kits using a universalized approach—differential sequence fill-in (DSF)-enabled sequential adapter ligation and amplification
|
US20090180931A1
(en)
|
2007-09-17 |
2009-07-16 |
Sequenom, Inc. |
Integrated robotic sample transfer device
|
US8728764B2
(en)
|
2008-10-02 |
2014-05-20 |
Illumina Cambridge Limited |
Nucleic acid sample enrichment for sequencing applications
|
US8182994B2
(en)
|
2009-09-15 |
2012-05-22 |
Illumina Cambridge Limited |
Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing
|
US20130183666A1
(en)
|
2012-01-18 |
2013-07-18 |
Marc N. Feiglin |
Partial genotyping by differential hybridization
|
AU2013236174A1
(en)
*
|
2012-03-22 |
2014-10-16 |
Kanagawa Prefectural Hospital Organization |
Method for detecting DNA having microsatellite region
|
CN104603290B
(zh)
|
2012-06-29 |
2019-02-01 |
Htg分子诊断有限公司 |
用于检测核苷酸变异的核酸酶保护方法
|
US10933417B2
(en)
|
2013-03-15 |
2021-03-02 |
Nanobiosym, Inc. |
Systems and methods for mobile device analysis of nucleic acids and proteins
|
JP6904910B2
(ja)
*
|
2016-02-10 |
2021-07-21 |
日本電気株式会社 |
Dna検査用チップ、dna検査方法、dna検査システム、及びdna検査チップ制御装置
|