DE69601637T2 - Nichttrennender chemilumineszenzassay durch spezifische bindung - Google Patents

Nichttrennender chemilumineszenzassay durch spezifische bindung

Info

Publication number
DE69601637T2
DE69601637T2 DE69601637T DE69601637T DE69601637T2 DE 69601637 T2 DE69601637 T2 DE 69601637T2 DE 69601637 T DE69601637 T DE 69601637T DE 69601637 T DE69601637 T DE 69601637T DE 69601637 T2 DE69601637 T2 DE 69601637T2
Authority
DE
Germany
Prior art keywords
solid phase
tracer
specific binding
analyte
bound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69601637T
Other languages
English (en)
Other versions
DE69601637D1 (de
Inventor
Eve Barlow
Eddie Carroll
Joseph Connolly
Michael Lee
Richard Martinelli
John Unger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Chiron Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Diagnostics Corp filed Critical Chiron Diagnostics Corp
Publication of DE69601637D1 publication Critical patent/DE69601637D1/de
Application granted granted Critical
Publication of DE69601637T2 publication Critical patent/DE69601637T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
DE69601637T 1995-06-29 1996-06-27 Nichttrennender chemilumineszenzassay durch spezifische bindung Expired - Fee Related DE69601637T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/496,549 US5783453A (en) 1995-06-29 1995-06-29 Non-separation specific binding chemiluminescent assay
PCT/IB1996/000617 WO1997001763A1 (en) 1995-06-29 1996-06-27 Non-separation specific binding chemiluminescent assay

Publications (2)

Publication Number Publication Date
DE69601637D1 DE69601637D1 (de) 1999-04-08
DE69601637T2 true DE69601637T2 (de) 1999-09-16

Family

ID=23973125

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69601637T Expired - Fee Related DE69601637T2 (de) 1995-06-29 1996-06-27 Nichttrennender chemilumineszenzassay durch spezifische bindung

Country Status (11)

Country Link
US (1) US5783453A (de)
EP (1) EP0835451B1 (de)
JP (1) JPH11508682A (de)
KR (1) KR19990028561A (de)
AT (1) ATE177208T1 (de)
AU (1) AU700057B2 (de)
BR (1) BR9609390A (de)
CA (1) CA2224825A1 (de)
DE (1) DE69601637T2 (de)
PL (1) PL324312A1 (de)
WO (1) WO1997001763A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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US6087088A (en) * 1997-01-31 2000-07-11 Bayer Corporation Binding assays using more than one label for determining analyte in the presence of interfering factors
US6146836A (en) * 1997-05-19 2000-11-14 Bayer Corporation Immunoassays using anti-allotypic monoclonal antibodies
US6056923A (en) * 1997-06-25 2000-05-02 Clmp, Inc. Dual injector for chemiluminescence immunoanalyzing system
US6355803B1 (en) * 1998-08-11 2002-03-12 Bayer Corporation Near infrared chemiluminescent acridinium compounds and uses thereof
GB2359625B (en) 1999-12-10 2004-10-20 Molecular Light Tech Res Ltd Monitoring oligonucleotide binding process using chemiluminescence quenching
AU2001293232A1 (en) * 2000-08-29 2002-03-13 The Rockefeller University Methods employing fluorescence quenching by metal surfaces
US6723851B2 (en) 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
US20090196852A1 (en) * 2008-02-04 2009-08-06 Watkinson D Tobin Compositions and methods for diagnosing and treating immune disorders
EP2274613B1 (de) * 2008-04-02 2014-06-04 Abbott Point Of Care, Inc. Verfahren für serologische agglutinierungsverfahren welche in einer dünnfilm-flüssigkeitsprobe durchgeführt werden
CN107478824A (zh) * 2017-08-11 2017-12-15 太原瑞盛生物科技有限公司 一种莱克多巴胺的磁微粒化学发光检测试剂盒及制备方法
CN107478827A (zh) * 2017-08-23 2017-12-15 太原瑞盛生物科技有限公司 一种伏马毒素的化学发光检测试剂盒及其制备方法
CN107356746A (zh) * 2017-08-23 2017-11-17 太原瑞盛生物科技有限公司 一种特布他林的磁微粒化学发光检测试剂盒及制备方法

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US3352791A (en) * 1965-01-22 1967-11-14 American Cyanamid Co Generation of light by the reaction of peroxide with heterocyclic derivatives
US3689391A (en) * 1970-05-13 1972-09-05 Synvar Ass Method for chemically initiating photochemical reactions
US4277437A (en) * 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4576912A (en) * 1978-11-30 1986-03-18 Technicon Instruments Corporation Fluoroimmunoassaying
IL64574A (en) * 1981-04-27 1986-01-31 Syva Co Method for determining the presence of an analyte by determination of the amount of fluorescence in competitive protein binding assays
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
EP0103469B1 (de) * 1982-09-10 1989-02-08 The Welsh National School of Medicine Immunologisches Verfahren zur Bestimmung von Stoffen
DE3310337A1 (de) * 1983-03-22 1984-09-27 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur durchfuehrung von hybridisierungsreaktionen
US4628037A (en) * 1983-05-12 1986-12-09 Advanced Magnetics, Inc. Binding assays employing magnetic particles
US4698302A (en) * 1983-05-12 1987-10-06 Advanced Magnetics, Inc. Enzymatic reactions using magnetic particles
US4695393A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4695392A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
JPS61217766A (ja) * 1985-03-23 1986-09-27 Tadashi Hara 蛋白質の定量方法および定量装置
US5017473A (en) * 1987-05-26 1991-05-21 Becton, Dickinson And Company Homogeneous chemiluminescence immunoassay using a light absorbing material
US4927769A (en) * 1987-07-08 1990-05-22 Ciba Corning Diagnostics Corp. Method for enhancement of chemiluminescence
JP3787352B2 (ja) * 1987-09-21 2006-06-21 ジェン−プローブ・インコーポレイテッド ハイブリダイゼーション保護検定
PT88665B (pt) * 1987-10-05 1992-12-31 Ml Tecnology Ventures Lp Metodo para a marcacao com ester de acridinio e purificacao de sondas nucleotidicas
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof
US5093270A (en) * 1989-05-24 1992-03-03 Ciba Corning Diagnostics Corp. Method for enhancing signal release from liposomes using water-miscible alcohols
CA2028012A1 (en) * 1989-10-23 1991-04-24 Randall Dimond Hybridization assay for campylobacter rrna
DE69125992T2 (de) * 1990-09-14 1997-08-21 Tosoh Corp Verfahren und Kit für Immunoassay
CA2046713A1 (en) * 1990-10-16 1992-04-17 Richard M. Martinelli Amplification of midivariant dna templates
ATE208039T1 (de) * 1991-05-22 2001-11-15 Dade Behring Marburg Gmbh Bestimmungsmethoden unter verwendung von induzierter lumineszenz
JP3053112B2 (ja) * 1991-07-10 2000-06-19 イゲン，インコーポレーテッド 粒子濃縮と化学発光検出を利用する改良発光検定のための方法ならびに装置
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays

Also Published As

Publication number Publication date
DE69601637D1 (de) 1999-04-08
KR19990028561A (ko) 1999-04-15
WO1997001763A1 (en) 1997-01-16
MX9710410A (es) 1998-07-31
AU700057B2 (en) 1998-12-17
BR9609390A (pt) 1999-05-18
EP0835451A1 (de) 1998-04-15
US5783453A (en) 1998-07-21
CA2224825A1 (en) 1997-01-16
JPH11508682A (ja) 1999-07-27
PL324312A1 (en) 1998-05-25
ATE177208T1 (de) 1999-03-15
AU6013396A (en) 1997-01-30
EP0835451B1 (de) 1999-03-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee