DE69535846D1 - Plasmakonzentrat und verbindungen zur abdichtung von gewebe - Google Patents

Plasmakonzentrat und verbindungen zur abdichtung von gewebe

Info

Publication number
DE69535846D1
DE69535846D1 DE69535846T DE69535846T DE69535846D1 DE 69535846 D1 DE69535846 D1 DE 69535846D1 DE 69535846 T DE69535846 T DE 69535846T DE 69535846 T DE69535846 T DE 69535846T DE 69535846 D1 DE69535846 D1 DE 69535846D1
Authority
DE
Germany
Prior art keywords
tissue sealant
patient
blood
sealant
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69535846T
Other languages
English (en)
Inventor
Richard D Antanavich
Randel Dorian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PlasmaSeal LLC
Original Assignee
PlasmaSeal LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23379205&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69535846(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PlasmaSeal LLC filed Critical PlasmaSeal LLC
Application granted granted Critical
Publication of DE69535846D1 publication Critical patent/DE69535846D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D67/00Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081After-treatment of organic or inorganic membranes
    • B01D67/0093Chemical modification
    • B01D67/00933Chemical modification by addition of a layer chemically bonded to the membrane
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D67/00Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081After-treatment of organic or inorganic membranes
    • B01D67/0093Chemical modification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/106Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/18Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D63/00Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/16Rotary, reciprocated or vibrated modules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2323/00Details relating to membrane preparation
    • B01D2323/30Cross-linking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0478Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with filters in the separation chamber
DE69535846T 1994-12-07 1995-12-07 Plasmakonzentrat und verbindungen zur abdichtung von gewebe Expired - Lifetime DE69535846D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/351,010 US5585007A (en) 1994-12-07 1994-12-07 Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
PCT/US1995/015171 WO1996017871A1 (en) 1994-12-07 1995-12-07 Plasma concentrate and tissue sealant compositions

Publications (1)

Publication Number Publication Date
DE69535846D1 true DE69535846D1 (de) 2008-10-30

Family

ID=23379205

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535846T Expired - Lifetime DE69535846D1 (de) 1994-12-07 1995-12-07 Plasmakonzentrat und verbindungen zur abdichtung von gewebe

Country Status (11)

Country Link
US (4) US5585007A (de)
EP (1) EP0743957B1 (de)
JP (1) JP4911807B2 (de)
KR (1) KR100411438B1 (de)
AT (1) ATE408446T1 (de)
AU (1) AU696278B2 (de)
BR (1) BR9506744A (de)
DE (1) DE69535846D1 (de)
MX (1) MX9603285A (de)
NZ (1) NZ297652A (de)
WO (1) WO1996017871A1 (de)

Families Citing this family (242)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733446A (en) * 1994-12-02 1998-03-31 Bristol-Myers Squibb Company Centrifuge with annular filter
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5643192A (en) * 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
CA2222506C (en) * 1995-06-06 2007-07-24 Quantic Biomedical Partners Device and method for concentrating plasma
WO1996039212A2 (en) * 1995-06-06 1996-12-12 Quantic Biomedical Partners Wound sealant preparation and application device and method
SE505274C2 (sv) * 1995-10-24 1997-07-28 Sten Andersson Användning av en hydrofob zeolit för avlägsnande av för injektionslösningar i läkemedelssammanhang använda konserveringsmedel från en proteinlösning
WO1997040864A1 (en) * 1996-04-30 1997-11-06 Medtronic, Inc. Method for making autologous fibrin sealant
WO2000062828A1 (en) * 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
AU4648697A (en) * 1996-09-23 1998-04-14 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US5899873A (en) * 1997-03-24 1999-05-04 Quest Medical, Inc. Biological fluid delivery system
ATE495786T1 (de) 1997-04-14 2011-02-15 Baxter Int Austragevorrichtung für flüssigkeiten welches abgemessene mengen unter anwendung eines kontrollierten soges abgibt
US6733472B1 (en) 1997-04-14 2004-05-11 Baxter International Inc. Sealant applicator tip and application method
US6770050B2 (en) 1997-04-14 2004-08-03 Baxter International Inc. Multipurpose fluid applicator and method, with surgical uses
US6331172B1 (en) 1997-04-14 2001-12-18 Baxter International Inc. Applicator for dispensing measured quantities with use of controlled suction
GB9711927D0 (en) * 1997-06-09 1997-08-06 Bristol Myers Squibb Co Compositions useful as fibrin sealants
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US7745106B2 (en) * 1997-06-24 2010-06-29 Cascade Medical Enterprises, Llc Methods and devices for separating liquid components
IT1292410B1 (it) * 1997-06-24 1999-02-08 Roberto Beretta Contenitore di pronto impiego per ottenere colla di fibrina autologa
DE19733899A1 (de) * 1997-08-05 1999-02-11 Ingo Flesch Verfahren und Vorrichtung zur Herstellung autologer, thrombozytärer Wachstumsfaktoren sowie System als Bestandteil einer Vorrichtung zur Herstellung autologer, thrombozytärer Wachtstumsfaktoren
JP2001520198A (ja) * 1997-10-17 2001-10-30 ハーベスト・テクノロジーズ・コーポレイション 血小板富有血漿からの成長因子富有化フィブリノーゲン濃縮物の調製
US20040092451A1 (en) * 1997-10-17 2004-05-13 Lou Blasetti Precipitation of growth-factor-enriched fibrinogen concentrate from platelet rich plasma
US6482223B1 (en) 1997-12-16 2002-11-19 Closys Corporation Clotting cascade initiating apparatus and methods of use
US6159232A (en) 1997-12-16 2000-12-12 Closys Corporation Clotting cascade initiating apparatus and methods of use and methods of closing wounds
US6478808B2 (en) 1997-12-17 2002-11-12 Closys Corporation Clotting cascade initiating apparatus and methods of use and methods of closing wounds
JP4493857B2 (ja) * 1998-04-20 2010-06-30 メドトロニック,インコーポレイテッド 自家移植フィブリンシーラント及び同種を作成する方法
US6461361B1 (en) 1998-05-01 2002-10-08 Baxter International Inc. Gas-driven spraying of mixed sealant agents
JP2002515309A (ja) * 1998-05-21 2002-05-28 バクスター・インターナショナル・インコーポレイテッド シーラントアプリケータおよび衝撃洗浄を使用する方法
US6475183B1 (en) 1998-06-03 2002-11-05 Baxter International Inc. Direct dual filling device for sealing agents
CA2301794C (en) * 1998-06-22 2004-05-18 Autologous Wound Therapy, Inc. Improved enriched platelet wound healant
AU2763099A (en) 1998-06-22 2000-01-10 Charles E. Worden Enriched platelet wound healant
US6083383A (en) * 1998-06-25 2000-07-04 Huang; Xun Yang Apparatus for production of fibrin ogen or fibrin glue
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
WO2000009181A2 (en) 1998-08-13 2000-02-24 Baxter International Inc. Multipurpose fluid applicator and method, with surgical uses
CA2336645C (en) 1998-08-18 2008-08-05 Baxter International Inc. Sealant applicator tip and application method
EP1140312B1 (de) * 1998-09-21 2009-07-22 Howard E. Purdum Verfahren und vorrichtung zur behandlung von blutplasma oder blutplasmakonzentrat
JP2003517997A (ja) * 1998-11-12 2003-06-03 ポリマー・バイオサイエンシス,インコーポレイテッド 急速な血液凝集及び止血に有用な止血ポリマー
US6516953B1 (en) 1998-12-05 2003-02-11 Becton, Dickinson And Company Device for separating components of a fluid sample
US6479298B1 (en) 1998-12-05 2002-11-12 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6406671B1 (en) * 1998-12-05 2002-06-18 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6280400B1 (en) * 1998-12-05 2001-08-28 Becton Dickinson And Company Device and method for separating component of a liquid sample
US20030069601A1 (en) * 1998-12-15 2003-04-10 Closys Corporation Clotting cascade initiating apparatus and methods of use
US6310036B1 (en) 1999-01-09 2001-10-30 Last Chance Tissue Adhesives Corporation High strength, Bio-compatible tissue adhesive and methods for treating vigorously bleeding surfaces
US6629919B2 (en) * 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
EP1057534A1 (de) * 1999-06-03 2000-12-06 Haemonetics Corporation Zentrifugentrommel mit Filterkern
US6472162B1 (en) * 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
US6716187B1 (en) * 1999-07-08 2004-04-06 Implant Innovations, Inc. Platelet concentration syringe kit
US6709413B1 (en) * 1999-09-02 2004-03-23 Riverview Hospital Platelet gel manufacturer for use in a closed corporeal circuit
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
JP3253290B2 (ja) * 1999-10-29 2002-02-04 照明 伊藤 検体処理システム
US6537503B1 (en) 1999-12-03 2003-03-25 Becton Dickinson And Company Device and method for separating components of a fluid sample
US6471069B2 (en) 1999-12-03 2002-10-29 Becton Dickinson And Company Device for separating components of a fluid sample
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
US6803022B2 (en) 1999-12-06 2004-10-12 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6575205B2 (en) 2000-12-07 2003-06-10 Baxter International Direct dual filling device for sealing agents
WO2001041650A1 (en) 1999-12-08 2001-06-14 Baxter International Inc. Direct dual filling device for sealing agents
ITAL990010U1 (it) * 1999-12-14 2001-06-14 Maria Cristina Sacchi Nuova metodica di laboratorio per preparare gel e membrane piastriniche ottenute dal concentrato piastrinico.
DE19960504A1 (de) * 1999-12-15 2001-08-16 Curasan Ag Regenerationsmittel
DE19960490A1 (de) * 1999-12-15 2001-07-12 Curasan Ag Regenerationsmittel
US20030095993A1 (en) * 2000-01-28 2003-05-22 Hanne Bentz Gel-infused sponges for tissue repair and augmentation
US6465256B1 (en) 2000-08-26 2002-10-15 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US20060094112A1 (en) * 2001-03-07 2006-05-04 Omotunde Babalola Biological scaffold
US6835316B2 (en) 2001-04-09 2004-12-28 Medtronic, Inc. Clam shell blood reservoir holder with index line
US6582350B2 (en) 2001-04-09 2003-06-24 Medtronic, Inc. Centrifuge container having curved linear shape
US6579219B2 (en) * 2001-04-09 2003-06-17 Medtronic, Inc. Centrifuge bag and methods of use
US6942880B1 (en) * 2001-04-09 2005-09-13 Medtronic, Inc. Autologous platelet gel having beneficial geometric shapes and methods of making the same
WO2002087662A1 (en) * 2001-04-27 2002-11-07 Nexell Therapeutics Inc. Cell processing and fluid transfer apparatus and method of use
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
US20030152639A1 (en) * 2001-07-03 2003-08-14 Calvin Britton Novel wound healing composition not containing bovine-derived activating reagents
US20040241146A1 (en) * 2001-08-27 2004-12-02 Biscup Robert S. Compositions, methods and apparatus for surgical procedures
US6589153B2 (en) 2001-09-24 2003-07-08 Medtronic, Inc. Blood centrifuge with exterior mounted, self-balancing collection chambers
US6649072B2 (en) 2001-11-16 2003-11-18 Robert Brandt Method for producing autologous platelet-rich plasma
US7101862B2 (en) 2001-12-31 2006-09-05 Area Laboratories, Llc Hemostatic compositions and methods for controlling bleeding
US8293530B2 (en) * 2006-10-17 2012-10-23 Carnegie Mellon University Method and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US8529956B2 (en) * 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US7608258B2 (en) * 2002-04-13 2009-10-27 Allan Mishra Method for treatment of tendinosis using platelet rich plasma
US6644365B1 (en) 2002-04-19 2003-11-11 Baxter International, Inc. Tilting direct dual filling device
JP2005523128A (ja) * 2002-04-24 2005-08-04 インターポア・オルソペディックス 血液分離及び濃縮システム
US6905612B2 (en) * 2003-03-21 2005-06-14 Hanuman Llc Plasma concentrate apparatus and method
US20030205538A1 (en) * 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20040182795A1 (en) * 2003-03-21 2004-09-23 Randel Dorian Apparatus and method for concentration of plasma from whole blood
US7179391B2 (en) * 2002-05-24 2007-02-20 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
EP1507543A4 (de) 2002-05-09 2006-07-26 Cambridgemed Inc Pharmazeutische zusammensetzung zur behandlung von wunden mit blutplasma oder serum
US20060278588A1 (en) * 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US6982038B2 (en) 2002-06-14 2006-01-03 Medtronic, Inc. Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma
US7297272B2 (en) 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
US20040120942A1 (en) * 2002-12-23 2004-06-24 Mcginnis Daniel Device and process for the preparation of autologous thrombin serum
US20040197319A1 (en) * 2003-03-24 2004-10-07 Paul Harch Wound healing composition derived from low platelet concentration plasma
ES2403357T3 (es) 2003-12-11 2013-05-17 Isto Technologies Inc. Sistema de cartílago particulado
US20070122906A1 (en) * 2003-12-29 2007-05-31 Allan Mishra Method of culturing cells
WO2005065269A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Compositions and method for decreasing the appearance of skin wrinkles
WO2005065242A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Method of treating cancer using platelet releasate
US7354515B2 (en) * 2004-02-23 2008-04-08 Millennium Medical Technologies, Inc. Fluid concentrator
US7837708B2 (en) * 2004-04-22 2010-11-23 Arthrex, Inc. Accelerated healing with intraoperative combination of suture and autogenous blood components
US8206448B2 (en) 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
US7597687B2 (en) 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
US20070286881A1 (en) * 2005-07-14 2007-12-13 Brian Burkinshsw Method, composition and kit for treating degenerated disc disease and discogenic pain
US8124075B2 (en) * 2004-07-16 2012-02-28 Spinal Restoration, Inc. Enhanced biological autologous tissue adhesive composition and methods of preparation and use
US7462268B2 (en) 2004-08-20 2008-12-09 Allan Mishra Particle/cell separation device and compositions
US20060094865A1 (en) * 2004-10-29 2006-05-04 Kapur Terri A Intraoperative method for isolating and concentrating autologous growth factors and for forming residual autologous growth factor compositions
EP1833452A1 (de) 2004-11-23 2007-09-19 Smith and Nephew, Inc. Kompositionsmischer
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
JP4510898B2 (ja) * 2005-02-07 2010-07-28 ハヌマン リミテッド ライアビリティ カンパニー 血漿濃縮装置
US7708152B2 (en) 2005-02-07 2010-05-04 Hanuman Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
JP4961354B2 (ja) 2005-02-07 2012-06-27 ハヌマン リミテッド ライアビリティ カンパニー 多血小板血漿濃縮装置および方法
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
EP2323774B1 (de) * 2005-04-20 2019-08-21 SpineSmith Holdings, LLC Fluidkonzentrator
US7694828B2 (en) 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
US8696662B2 (en) 2005-05-12 2014-04-15 Aesculap Ag Electrocautery method and apparatus
US9339323B2 (en) 2005-05-12 2016-05-17 Aesculap Ag Electrocautery method and apparatus
US7862565B2 (en) 2005-05-12 2011-01-04 Aragon Surgical, Inc. Method for tissue cauterization
US8728072B2 (en) 2005-05-12 2014-05-20 Aesculap Ag Electrocautery method and apparatus
WO2007005820A1 (en) * 2005-06-30 2007-01-11 Cytomedix, Inc. Method for treating wounds with enriched platelet wound healant
US8048297B2 (en) 2005-08-23 2011-11-01 Biomet Biologics, Llc Method and apparatus for collecting biological materials
US7771590B2 (en) * 2005-08-23 2010-08-10 Biomet Manufacturing Corp. Method and apparatus for collecting biological materials
EP1916964A4 (de) 2005-08-26 2015-11-04 Zimmer Inc Implantate und verfahren zur behebung, ersetzung und behandlung von gelenkkrankheiten
DE102006002258B4 (de) * 2006-01-17 2008-08-21 Siemens Ag Modul zur Aufbereitung einer biologischen Probe, Biochip-Satz und Verwendung des Moduls
US20070248653A1 (en) * 2006-04-20 2007-10-25 Cochrum Kent C Hemostatic compositions and methods for controlling bleeding
US9096839B2 (en) * 2006-04-26 2015-08-04 Arteriocyte Medical Systems, Inc. Compositions and methods of preparation thereof
US8574229B2 (en) 2006-05-02 2013-11-05 Aesculap Ag Surgical tool
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
JP5258765B2 (ja) * 2006-07-31 2013-08-07 ハヌマン リミテッド ライアビリティ カンパニー 血小板富化血漿およびこれらの濃縮物を調製する装置および方法
US20080045964A1 (en) 2006-08-16 2008-02-21 Allan Mishra Device for cartilage repair
US8623842B2 (en) 2006-09-27 2014-01-07 Hemostasis, Llc Hemostatic agent and method
US8529958B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US8163549B2 (en) * 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
AU2008207828B2 (en) * 2007-01-25 2013-09-19 Hyperbranch Medical Technology, Inc. Applicators for multiple component formulations and the like, and methods of use thereof
US8034014B2 (en) 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth
KR101284154B1 (ko) 2007-03-07 2013-07-10 가부시끼가이샤 제이엠에스 혈청조제방법 및 혈청조제장치
JP5479319B2 (ja) 2007-04-12 2014-04-23 バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー ブイ式懸濁液分画システム
US20090012629A1 (en) 2007-04-12 2009-01-08 Isto Technologies, Inc. Compositions and methods for tissue repair
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US20080269762A1 (en) * 2007-04-25 2008-10-30 Biomet Manufacturing Corp. Method and device for repair of cartilage defects
US7901344B2 (en) * 2007-05-11 2011-03-08 Biomet Biologics, Llc Methods of reducing surgical complications in cancer patients
WO2009002849A2 (en) * 2007-06-22 2008-12-31 Millennium Medical Technologies, Inc. Fluid concentrator, autologous concentrated body fluids, and uses thereof
US20090011043A1 (en) * 2007-07-03 2009-01-08 Hua Xie Tissue sealant made from whole blood
WO2009049318A2 (en) * 2007-10-12 2009-04-16 Bakaltcheva Irina B Freeze-dried plasma formats for the trauma care field
US8961448B2 (en) * 2008-01-28 2015-02-24 Peter Forsell Implantable drainage device
US20090192528A1 (en) * 2008-01-29 2009-07-30 Biomet Biologics, Inc. Method and device for hernia repair
US8870867B2 (en) 2008-02-06 2014-10-28 Aesculap Ag Articulable electrosurgical instrument with a stabilizable articulation actuator
US8075468B2 (en) 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
US8753690B2 (en) 2008-02-27 2014-06-17 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
EP2567692B1 (de) * 2008-02-27 2016-04-06 Biomet Biologics, LLC Verwendung einer Vorrichtung zur Erzeugung Interleukin-1-rezeptorantagonistreicher Lösungen
WO2009111338A1 (en) * 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
US9061087B2 (en) * 2008-03-04 2015-06-23 Hemostasis, Llc Method of making a hemostatic sponge wound dressing comprising subjecting the sponge to water vapor
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US8702637B2 (en) 2008-04-14 2014-04-22 Haemonetics Corporation System and method for optimized apheresis draw and return
US8454548B2 (en) 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US8628489B2 (en) 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US8999001B2 (en) * 2008-04-21 2015-04-07 Ao Technology Ag Biocompatible implant
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
WO2010042658A1 (en) 2008-10-07 2010-04-15 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
EP2337793A4 (de) * 2008-10-08 2013-04-10 Thrombodyne Inc Verfahren zur herstellung von konzentriertem fibrinogen und plättchenhaltigen zusammensetzungen
EP2337617A4 (de) * 2008-10-09 2013-06-12 Bioparadox Llc Plättchenreiche plasmaformulierungen für herzbehandlungen
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8834402B2 (en) 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US20100233282A1 (en) * 2009-03-13 2010-09-16 Allan Mishra Device and methods for delivery of bioactive materials to the right side of the heart
KR20090033859A (ko) 2009-03-17 2009-04-06 윤근진 혈장 가온기
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9433700B2 (en) 2009-04-27 2016-09-06 Medibeacon Inc. Tissue sealant compositions, vascular closure devices, and uses thereof
US8540078B2 (en) * 2009-06-16 2013-09-24 Biomet Biologics, Llc Liquid separation from adipose tissue
US8790519B2 (en) * 2009-06-16 2014-07-29 Biomet Biologics, Llc Liquid separation from adipose tissue
US8734854B2 (en) * 2009-07-09 2014-05-27 Orogen Biosciences Inc. Process for removing growth factors from platelets
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8454907B2 (en) 2009-08-12 2013-06-04 Orogen Holdings, Llc Growth factor extractor
US9763875B2 (en) 2009-08-27 2017-09-19 Biomet Biologics, Llc Implantable device for production of interleukin-1 receptor antagonist
US20110052561A1 (en) * 2009-08-27 2011-03-03 Biomet Biologics,LLC Osteolysis treatment
US20110052663A1 (en) * 2009-09-01 2011-03-03 Hemostasis, Llc Hemostatic Sponge with Enzyme and Method of Manufacture
WO2011028733A1 (en) 2009-09-04 2011-03-10 Allan Mishra Compositions and minimally invasive methods for treating cancer
KR101080295B1 (ko) 2010-01-22 2011-11-04 은형일 자가혈 필러 조성물
WO2011097469A2 (en) 2010-02-04 2011-08-11 Aragon Surgical, Inc. Laparoscopic radiofrequency surgical device
US8419727B2 (en) 2010-03-26 2013-04-16 Aesculap Ag Impedance mediated power delivery for electrosurgery
US8827992B2 (en) 2010-03-26 2014-09-09 Aesculap Ag Impedance mediated control of power delivery for electrosurgery
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US10231721B2 (en) 2010-06-24 2019-03-19 St. Croix Surgical Systems, Llc Failsafe percutaneous wound barrier
EP2611456A2 (de) 2010-09-03 2013-07-10 Biomet Biologics, LLC Verfahren und zusammensetzungen zur herstellung von interleukin-1-rezeptor-antagonisten
US20120065600A1 (en) * 2010-09-10 2012-03-15 E. I. Du Pont De Nemours And Company. Device for dispensing microliter quantities of a material into a longitudinally extending wound site
US9173698B2 (en) 2010-09-17 2015-11-03 Aesculap Ag Electrosurgical tissue sealing augmented with a seal-enhancing composition
US9555171B2 (en) 2010-09-30 2017-01-31 Depuy Mitek, Llc Methods and devices for collecting separate components of whole blood
CN103221078B (zh) 2010-11-05 2015-09-16 赫摩耐提克斯公司 用于自动化血小板洗涤的系统和方法
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US9011684B2 (en) 2011-03-07 2015-04-21 Spinesmith Holdings, Llc Fluid concentrator with removable cartridge
US9011846B2 (en) 2011-05-02 2015-04-21 Biomet Biologics, Llc Thrombin isolated from blood and blood fractions
WO2019226654A1 (en) 2018-05-21 2019-11-28 Fenwal, Inc. Systems and methods for optimization of plasma collection volumes
US11386993B2 (en) 2011-05-18 2022-07-12 Fenwal, Inc. Plasma collection with remote programming
US9339327B2 (en) 2011-06-28 2016-05-17 Aesculap Ag Electrosurgical tissue dissecting device
DE102011122227A1 (de) 2011-12-23 2013-06-27 Medizinische Hochschule Hannover Verfahren und Vorrichtung zur Herstellung eines bioartifiziellen Gewebekonstrukts
WO2013111130A1 (en) 2012-01-23 2013-08-01 Estar Technologies Ltd A system and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma(prp)
US20130202656A1 (en) 2012-02-03 2013-08-08 Dynasil Biomedical Corporation Systems and kits for the fabrication of tissue patches
EP2628484B9 (de) 2012-02-17 2016-08-17 Opko Lab Europe Sl. Thrombozytenreiche Plasmazusammensetzung
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
AU2013323621B2 (en) 2012-09-25 2016-04-14 Stem Cell Partners Llc Method and apparatus for preparing single donor thrombin serum
KR102174907B1 (ko) 2012-09-26 2020-11-05 아에스쿨랍 아게 조직을 커팅 및 봉합하기 위한 장치
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9878011B2 (en) 2013-03-15 2018-01-30 Biomet Biologics, Llc Treatment of inflammatory respiratory disease using biological solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9758806B2 (en) 2013-03-15 2017-09-12 Biomet Biologics, Llc Acellular compositions for treating inflammatory disorders
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
US9757330B2 (en) 2013-10-18 2017-09-12 Industrial Technology Research Institute Recipe for in-situ gel, and implant, drug delivery system formed thereby
EP3074507B1 (de) 2013-11-26 2022-01-05 Biomet Biologics, LLC Verfahren zur vermittlung von makrophagenphänotypen
WO2015117007A1 (en) 2014-01-31 2015-08-06 Dsm Ip Assets B.V. Adipose tissue centrifuge and method of use
US9550028B2 (en) 2014-05-06 2017-01-24 Biomet Biologics, LLC. Single step desiccating bead-in-syringe concentrating device
US10441635B2 (en) 2014-11-10 2019-10-15 Biomet Biologics, Llc Methods of treating pain using protein solutions
US9763800B2 (en) 2015-03-18 2017-09-19 Biomet C. V. Implant configured for hammertoe and small bone fixation
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
EP3331577A4 (de) 2015-08-07 2019-07-17 Xcede Technologies, Inc. Klebstoffzusammensetzungen und zugehörige verfahren
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
DE102015216241A1 (de) * 2015-08-25 2017-03-02 Bbi-Biotech Gmbh Behälter und Verfahren zur Filtration einer Suspension
US10501715B1 (en) 2015-09-11 2019-12-10 Mark H. Widick System for the formation of fibrin foam
US11629323B1 (en) * 2015-09-11 2023-04-18 Fibrin, Llc System for the formation of fibrin foam
ITUB20154668A1 (it) * 2015-10-14 2017-04-14 Mario Goisis Dispositivo per la filtrazione del grasso estratto con procedure chirurgiche di liposuzione
WO2017070758A1 (pt) * 2015-10-27 2017-05-04 Silva Junior Hélio Nogueira Da Dispositivo para preparo de curativo biológico de fibrina autóloga
WO2018132594A1 (en) 2017-01-11 2018-07-19 Spinalcyte, Llc Methods of enhancing fibroblast therapeutic activity
US11202848B2 (en) 2017-03-08 2021-12-21 Baxter International Inc. Surgical adhesive able to glue in wet conditions
US10912859B2 (en) 2017-03-08 2021-02-09 Baxter International Inc. Additive able to provide underwater adhesion
US10758652B2 (en) 2017-05-30 2020-09-01 Haemonetics Corporation System and method for collecting plasma
US10792416B2 (en) 2017-05-30 2020-10-06 Haemonetics Corporation System and method for collecting plasma
WO2019074886A1 (en) 2017-10-09 2019-04-18 Terumo Bct Biotechnologies, Llc LYOPHILIZATION CONTAINER AND METHOD OF USE
US11065376B2 (en) 2018-03-26 2021-07-20 Haemonetics Corporation Plasmapheresis centrifuge bowl
US11412967B2 (en) 2018-05-21 2022-08-16 Fenwal, Inc. Systems and methods for plasma collection
EP3801286A4 (de) * 2018-06-07 2022-03-16 University of Cincinnati Verfahren und vorrichtungen zur vorbehandlung von proben auf hydrogel- und aerogelbasis
JP2021531059A (ja) 2018-07-09 2021-11-18 ハヌマン ペリカン,インコーポレイテッド 血液を処理するための装置および方法
WO2020060809A1 (en) 2018-09-17 2020-03-26 Rejuvablast LLC Combination grafts for tissue repair or regeneration applications
US20220088589A1 (en) 2019-01-21 2022-03-24 Eclipse Medcorp, Llc Methods, Systems and Apparatus for Separating Components of a Biological Sample
CA3224729A1 (en) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system

Family Cites Families (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE56103C (de) * A. SCHLEE in Altona, Blücherstrafse 24 Löschrolle
DD56103A (de) *
US32089A (en) * 1861-04-16 Carpet-fastener
US2553004A (en) * 1949-03-11 1951-05-15 Rabatine Michael Dividing protractor
SE169293C1 (de) * 1958-03-13 1959-11-10
SE358894B (de) * 1961-10-25 1973-08-13 Pharmacia Ab
DK113248B (da) * 1963-09-02 1969-03-03 Pharmacia Ab Fremgangsmåde til fremstilling af med en eller flere mono- eller dihydroxyalkylgrupper substitueret dekstran.
US3441143A (en) * 1967-02-10 1969-04-29 Marvel Eng Co Plural element filter assembly
USRE32089E (en) 1970-08-25 1986-03-04 Amicon Corporation Blood fractionating process and apparatus for carrying out same
SE452109B (sv) * 1973-01-29 1987-11-16 Pharmacia Ab Rengoringsmedel for vetskande utvertes sarytor
US4537767A (en) * 1973-01-29 1985-08-27 Pharmacia Aktiebolag Method for cleansing fluid discharging skin surfaces, wounds and mucous membranes and means for carrying out the method
US3894952A (en) * 1974-02-27 1975-07-15 Becton Dickinson Co Serum/plasma separator assembly having interface-seeking piston
US4059108A (en) * 1974-08-15 1977-11-22 Haemonetics Corporation Process for pheresis procedure and disposable pheresis bowl therefor
US4204537A (en) * 1974-08-15 1980-05-27 Haemonetics Corporation Process for pheresis procedure and disposable plasma
US3972812A (en) * 1975-05-08 1976-08-03 Becton, Dickinson And Company Blood serum separation filter disc
US5217426A (en) * 1977-08-12 1993-06-08 Baxter International Inc. Combination disposable plastic blood receiving container and blood component centrifuge
US4303193A (en) * 1979-01-22 1981-12-01 Haemonetics Corporation Apparatus for separating blood into components thereof
AT359652B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
AT359653B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
US4314823A (en) * 1979-03-05 1982-02-09 Dionex Corporation Combination apparatus and method for chromatographic separation and quantitative analysis of multiple ionic species
JPS5917386B2 (ja) * 1979-03-23 1984-04-20 テルモ株式会社 血液分離方法および装置
US4300717A (en) * 1979-04-02 1981-11-17 Haemonetics Corporation Rotary centrifuge seal
DE3165646D1 (en) * 1980-05-08 1984-09-27 Terumo Corp Apparatus for separating blood
US4424132A (en) * 1981-02-05 1984-01-03 Asahi Kasei Kogyo Kabushiki Kaisha Apparatus and method for separating blood components
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
US4322298A (en) * 1981-06-01 1982-03-30 Advanced Blood Component Technology, Inc. Centrifugal cell separator, and method of use thereof
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
ATE20824T1 (de) * 1981-06-25 1986-08-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung.
DE3175003D1 (en) * 1981-06-25 1986-08-28 Serapharm Gmbh & Co Kg Enriched plasma derivative for promoting wound sealing and wound healing
US4735726A (en) * 1981-07-22 1988-04-05 E. I. Du Pont De Nemours And Company Plasmapheresis by reciprocatory pulsatile filtration
GB2104401B (en) * 1981-08-25 1985-03-20 Krauss Maffei Ag Support plate for centrifuges
DE3203775A1 (de) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
DE3212412C2 (de) * 1982-04-02 1986-01-02 Dr. Ruhland Nachf. GmbH, 8425 Neustadt Gewebeverklebbare kollagene Wundauflage
JPS5928766A (ja) * 1982-08-10 1984-02-15 Sony Corp 遅延回路
US4680025A (en) * 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods
JPS59501538A (ja) * 1982-08-24 1984-08-30 バクスタ−、インタ−ナショナル、インコ−ポレイテッド 血液成分採取セット
EP0109374A1 (de) * 1982-10-08 1984-05-23 Antoon Soetens Vorrichtung zum Auffangen von Sonnenenergie auf einem Dach oder ähnlichem
US5034135A (en) * 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US4755301A (en) * 1983-08-15 1988-07-05 W. R. Grace & Co. Apparatus and method for centrifugal recovery of retentate
US4632761A (en) * 1983-08-15 1986-12-30 W. R. Grace & Co. Centrifugal microconcentrator and methods for its use
US4672969A (en) * 1983-10-06 1987-06-16 Sonomo Corporation Laser healing method
CH665565A5 (de) * 1983-10-22 1988-05-31 Mitsui Toatsu Chemicals Verfahren zur steuerung der konzentration einer eine makromolekulare verbindung enthaltenden waessrigen loesung oder emulsion.
JPS60250014A (ja) * 1984-05-28 1985-12-10 Mitsui Toatsu Chem Inc 濃縮用樹脂
AT379311B (de) * 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
JPS6144825A (ja) * 1984-08-09 1986-03-04 Unitika Ltd 止血剤
US4627879A (en) * 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
US4928603A (en) * 1984-09-07 1990-05-29 The Trustees Of Columbia University In The City Of New York Method of preparing a cryoprecipitated suspension and use thereof
JPH0720873B2 (ja) * 1984-11-29 1995-03-08 キュラテック・インコ−ポレ−テッド 創傷治癒剤
US4639316A (en) * 1984-12-14 1987-01-27 Becton, Dickinson And Company Automatic liquid component separator
AT382783B (de) * 1985-06-20 1987-04-10 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
US4871462A (en) * 1985-12-23 1989-10-03 Haemonetics Corporation Enhanced separation of blood components
US4755300A (en) * 1985-12-23 1988-07-05 Haemonetics Corporation Couette membrane filtration apparatus for separating suspended components in a fluid medium using high shear
AU578554B2 (en) * 1986-01-24 1988-10-27 Japanese Red Cross Society Centrifugal method of separating blood components
US5112490A (en) * 1986-02-19 1992-05-12 Jon Turpen Sample filtration, separation and dispensing device
DE3622642A1 (de) * 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
US4943273A (en) * 1986-07-22 1990-07-24 Haemonetics Corporation Disposable centrifuge bowl for blood processing
US4983158A (en) * 1986-07-22 1991-01-08 Haemonetics Corporation Plasmapheresis centrifuge bowl
US4714457A (en) * 1986-09-15 1987-12-22 Robert Alterbaum Method and apparatus for use in preparation of fibrinogen from a patient's blood
DK475386D0 (da) * 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
CH673117A5 (de) * 1986-12-10 1990-02-15 Ajinomoto Kk
US5104526A (en) * 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US5370802A (en) * 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US4832851A (en) * 1987-02-02 1989-05-23 W. R. Grace & Co. Centrifugal force-enhanced filtration of fluids
US4983157A (en) * 1987-03-23 1991-01-08 Ceramics Process Systems Corp. Centrifugation system using static layer
IT1203461B (it) * 1987-04-08 1989-02-15 Dideco Spa Cella per la centrifugazione del sangue
US5260420A (en) * 1987-07-30 1993-11-09 Centre Regional De Transfusion Sanguine De Lille Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
US4957638A (en) * 1987-10-23 1990-09-18 Becton Dickinson And Company Method for separating the cellular components of blood samples
US5290552A (en) * 1988-05-02 1994-03-01 Matrix Pharmaceutical, Inc./Project Hear Surgical adhesive material
ES2064439T3 (es) * 1988-05-02 1995-02-01 Project Hear Material adhesivo quirurgico.
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
AU617265B2 (en) * 1988-06-23 1991-11-21 Asahi Medical Co. Ltd. Method for separating blood into blood components, and blood components separator unit
US4874368A (en) * 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4902281A (en) * 1988-08-16 1990-02-20 Corus Medical Corporation Fibrinogen dispensing kit
JPH02129224A (ja) * 1988-11-10 1990-05-17 Terumo Corp フィブリンの製造法
US5002571A (en) * 1989-02-06 1991-03-26 Donnell Jr Francis E O Intraocular lens implant and method of locating and adhering within the posterior chamber
SE8900586L (sv) * 1989-02-21 1990-08-22 Pharmacia Ab Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader
EP0394510A1 (de) * 1989-04-24 1990-10-31 Mochida Pharmaceutical Co., Ltd. Verfahren zur Bestimmung eines tumorassozierten Antigens in winzigen Mengen von Brustwarzen-Ausfluss und Vorrichtung für eine solche Bestimmung
US5226877A (en) * 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
US5000970A (en) * 1989-06-30 1991-03-19 Horizons International Foods, Inc. Process for preparing reheatable french fried potatoes
US5316674A (en) * 1989-09-12 1994-05-31 Pall Corporation Device for processing blood for human transfusion
US5258126A (en) * 1989-09-12 1993-11-02 Pall Corporation Method for obtaining platelets
US5100564A (en) * 1990-11-06 1992-03-31 Pall Corporation Blood collection and processing system
US5152905A (en) * 1989-09-12 1992-10-06 Pall Corporation Method for processing blood for human transfusion
US5104375A (en) * 1989-10-16 1992-04-14 Johnson & Johnson Medical, Inc. Locking holder for a pair of syringes and method of use
US5030215A (en) * 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
US5219328A (en) * 1990-01-03 1993-06-15 Cryolife, Inc. Fibrin sealant delivery method
NL9000090A (nl) * 1990-01-15 1991-08-01 Harimex Ligos Bv Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat.
US5185001A (en) * 1990-01-18 1993-02-09 The Research Foundation Of State University Of New York Method of preparing autologous plasma fibrin and application apparatus therefor
US5045048A (en) * 1990-03-29 1991-09-03 Haemonetics Corporation Rotary centrifuge bowl and seal for blood processing
US5204537A (en) * 1990-03-30 1993-04-20 Recognition Equipment Incorporated Thickness sensor comprising a leaf spring means, and a light sensor
US5420250A (en) * 1990-08-06 1995-05-30 Fibrin Corporation Phase transfer process for producing native plasma protein concentrates
US5173295A (en) * 1990-10-05 1992-12-22 Advance Biofactures Of Curacao, N.V. Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor
US5112484A (en) * 1990-10-11 1992-05-12 Zuk, Inc. Filtration apparatus
US5217627A (en) * 1990-11-06 1993-06-08 Pall Corporation System and method for processing biological fluid
US5137832A (en) * 1991-01-02 1992-08-11 Becton Dickinson & Company Quantification of fibrinogen in whole blood samples contained in a tube using a float to separate materials
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5156613A (en) * 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
SE9101853D0 (sv) * 1991-06-17 1991-06-17 Jonas Wadstroem Improved tissue ashesive
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.
DE4126341C1 (de) * 1991-08-09 1993-01-28 Fresenius Ag, 6380 Bad Homburg, De
BR9103724A (pt) * 1991-08-29 1993-03-30 Univ Estadual Paulista Julio D Cola de fibrina derivada de veneno de cobra e processo para sua preparacao
WO1993005067A1 (en) * 1991-09-05 1993-03-18 Baxter International, Inc. Topical fibrinogen complex
DE4129516C2 (de) * 1991-09-06 2000-03-09 Fresenius Ag Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile
EP0534178B1 (de) * 1991-09-27 2001-04-18 Omrix Biopharmaceuticals S.A. Verbesserter Gewebekleber, zubereitet aus Kryopräzipitat
US5190057A (en) * 1991-12-13 1993-03-02 Faezeh Sarfarazi Sarfarazi method of closing a corneal incision
DE4202667C1 (de) * 1992-01-29 1993-05-13 Behringwerke Ag, 3550 Marburg, De
US5298016A (en) * 1992-03-02 1994-03-29 Advanced Haemotechnologies Apparatus for separating plasma and other wastes from blood
US5403272A (en) * 1992-05-29 1995-04-04 Baxter International Inc. Apparatus and methods for generating leukocyte free platelet concentrate
DK83092D0 (da) * 1992-06-24 1992-06-24 Unes As Fremgangsmaade til udvinding af thrombin
US5443481A (en) * 1992-07-27 1995-08-22 Lee; Benjamin I. Methods and device for percutaneous sealing of arterial puncture sites
AU4926193A (en) * 1992-09-21 1994-04-12 Vitaphore Corporation Embolization plugs for blood vessels
FR2696095B1 (fr) * 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
CN1074709A (zh) * 1992-11-26 1993-07-28 刘高东 一种凝血酶的制做方法
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
US5290918A (en) * 1993-02-23 1994-03-01 Haemacure Biotech Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by acidic precipitation
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
US5411885A (en) * 1993-12-17 1995-05-02 New York Blood Center, Inc. Methods for tissue embedding and tissue culturing
US5733446A (en) * 1994-12-02 1998-03-31 Bristol-Myers Squibb Company Centrifuge with annular filter
US5510102A (en) * 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives

Also Published As

Publication number Publication date
EP0743957B1 (de) 2008-09-17
US6063297A (en) 2000-05-16
US5585007A (en) 1996-12-17
WO1996017871A1 (en) 1996-06-13
US5788662A (en) 1998-08-04
MX9603285A (es) 1997-07-31
AU696278B2 (en) 1998-09-03
EP0743957A4 (de) 2000-11-15
ATE408446T1 (de) 2008-10-15
EP0743957A1 (de) 1996-11-27
AU4286396A (en) 1996-06-26
BR9506744A (pt) 1997-09-16
JPH09509432A (ja) 1997-09-22
US6214338B1 (en) 2001-04-10
JP4911807B2 (ja) 2012-04-04
NZ297652A (en) 1997-05-26
KR100411438B1 (ko) 2004-04-21

Similar Documents

Publication Publication Date Title
DE69535846D1 (de) Plasmakonzentrat und verbindungen zur abdichtung von gewebe
CA2182862A1 (en) Plasma concentrate and tissue sealant compositions
DE69939871D1 (de) Gerät und verfahren zur herstellung von stabilem langzeitigem thrombin aus plasma sowie so hergestelltes thrombin
Carless et al. Fibrin sealant use for minimising peri‐operative allogeneic blood transfusion
Oliver et al. A prospective, randomized, double-blind trial of the use of fibrin sealant for face lifts
EP1397167B1 (de) Wundverschlusssystem und verfahren
Hellstern et al. Manufacture and in vitro characterization of a solvent/detergent-treated human plasma
CA1119516A (en) Tissue adhesive
HK1046241A1 (en) Autologous thrombin
DePalma et al. The preparation of fibrinogen concentrate for use as fibrin glue by four different methods
DK158282B (da) Fremgangsmaade til fremstilling af et fast fibrinogenpraeparat
DE68918155D1 (de) Chirurgisches Klebstoffmaterial.
Burnouf-Radosevich et al. Biochemical and physical properties of a solvent-detergent-treated fibrin glue
EP1023017A1 (de) Fibrinkleber ohne fibrinogen sowie "bio-verschliessende" mittel und methoden
DE69132563D1 (de) Ausgabeverfahren für fibrindichtungsmittel
BR9812228A (pt) Esponja de fibrina, processo para a preparação da mesma, uso de uma esponja de fibrina, e, kit.
Kjaergard et al. Preparation of autologous fibrin glue from pericardial blood
JP2668762B2 (ja) 寒冷沈降物を用いて製造した改良組織接着剤
Buchta et al. Fibrin sealant produced by the CryoSeal® FS system: product chemistry, material properties and possible preparation in the autologous preoperative setting
JPH02129224A (ja) フィブリンの製造法
EP1190724B8 (de) Verwendung von Antifibrinolytika für die Präparation und Herstellung von Tupfern, Kompressen oder Pflaster
Burnouf et al. Blood‐derived biomaterials: fibrin sealant, platelet gel and platelet fibrin glue
Park et al. Biochemical aspects of autologous fibrin glue derived from ammonium sulfate precipitation
Suwannuraks et al. The use of fibrin glue as an operative sealant in dental extraction in bleeding disorder patients
US6613324B1 (en) Adhesive for the gluing of biological tissues

Legal Events

Date Code Title Description
8364 No opposition during term of opposition