DE69534080D1 - Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren - Google Patents

Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren

Info

Publication number
DE69534080D1
DE69534080D1 DE69534080T DE69534080T DE69534080D1 DE 69534080 D1 DE69534080 D1 DE 69534080D1 DE 69534080 T DE69534080 T DE 69534080T DE 69534080 T DE69534080 T DE 69534080T DE 69534080 D1 DE69534080 D1 DE 69534080D1
Authority
DE
Germany
Prior art keywords
reservoirs
biodegradable
devices
agent
solid tumors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69534080T
Other languages
English (en)
Other versions
DE69534080T2 (de
Inventor
Henry Brem
J Langer
J Domb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Massachusetts Institute of Technology
Original Assignee
Johns Hopkins University
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23089835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69534080(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Johns Hopkins University, Massachusetts Institute of Technology filed Critical Johns Hopkins University
Publication of DE69534080D1 publication Critical patent/DE69534080D1/de
Application granted granted Critical
Publication of DE69534080T2 publication Critical patent/DE69534080T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE69534080T 1994-08-02 1995-08-02 Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren Revoked DE69534080T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/284,341 US5626862A (en) 1994-08-02 1994-08-02 Controlled local delivery of chemotherapeutic agents for treating solid tumors
PCT/US1995/009805 WO1996003984A1 (en) 1994-08-02 1995-08-02 Controlled local delivery of chemotherapeutic agents for treating solid tumors
US284341 2002-10-31

Publications (2)

Publication Number Publication Date
DE69534080D1 true DE69534080D1 (de) 2005-04-21
DE69534080T2 DE69534080T2 (de) 2006-04-13

Family

ID=23089835

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534080T Revoked DE69534080T2 (de) 1994-08-02 1995-08-02 Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren

Country Status (9)

Country Link
US (4) US5626862A (de)
EP (1) EP0774964B1 (de)
JP (1) JPH10505587A (de)
AT (1) ATE290860T1 (de)
CA (1) CA2196304C (de)
DE (1) DE69534080T2 (de)
ES (1) ES2243940T3 (de)
PT (1) PT774964E (de)
WO (1) WO1996003984A1 (de)

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ATE290860T1 (de) 2005-04-15
CA2196304C (en) 2011-02-15
WO1996003984A1 (en) 1996-02-15
EP0774964B1 (de) 2005-03-16
ES2243940T3 (es) 2005-12-01
US5846565A (en) 1998-12-08
US5651986A (en) 1997-07-29
DE69534080T2 (de) 2006-04-13
EP0774964A1 (de) 1997-05-28
US5626862A (en) 1997-05-06
CA2196304A1 (en) 1996-02-15
PT774964E (pt) 2005-08-31
USRE37410E1 (en) 2001-10-16

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