DE69524175D1 - Vermittler, geeignet für die elektrochemische Regenerierung von NADH, NADPH oder deren Analogen - Google Patents

Vermittler, geeignet für die elektrochemische Regenerierung von NADH, NADPH oder deren Analogen

Info

Publication number
DE69524175D1
DE69524175D1 DE69524175T DE69524175T DE69524175D1 DE 69524175 D1 DE69524175 D1 DE 69524175D1 DE 69524175 T DE69524175 T DE 69524175T DE 69524175 T DE69524175 T DE 69524175T DE 69524175 D1 DE69524175 D1 DE 69524175D1
Authority
DE
Germany
Prior art keywords
nadh
nadph
analogs
electrochemical regeneration
electrochemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69524175T
Other languages
English (en)
Other versions
DE69524175T2 (de
Inventor
Paul F Corey
Matthew K Musho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69524175D1 publication Critical patent/DE69524175D1/de
Publication of DE69524175T2 publication Critical patent/DE69524175T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode
DE69524175T 1994-09-29 1995-09-18 Vermittler, geeignet für die elektrochemische Regenerierung von NADH, NADPH oder deren Analogen Expired - Lifetime DE69524175T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/314,718 US5498542A (en) 1994-09-29 1994-09-29 Electrode mediators for regeneration of NADH and NADPH

Publications (2)

Publication Number Publication Date
DE69524175D1 true DE69524175D1 (de) 2002-01-10
DE69524175T2 DE69524175T2 (de) 2002-05-02

Family

ID=23221146

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524175T Expired - Lifetime DE69524175T2 (de) 1994-09-29 1995-09-18 Vermittler, geeignet für die elektrochemische Regenerierung von NADH, NADPH oder deren Analogen

Country Status (6)

Country Link
US (1) US5498542A (de)
EP (1) EP0704535B1 (de)
JP (1) JP3814314B2 (de)
AU (1) AU689630B2 (de)
CA (1) CA2152410C (de)
DE (1) DE69524175T2 (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498542A (en) * 1994-09-29 1996-03-12 Bayer Corporation Electrode mediators for regeneration of NADH and NADPH
US5866353A (en) * 1996-12-09 1999-02-02 Bayer Corporation Electro chemical biosensor containing diazacyanine mediator for co-enzyme regeneration
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6500571B2 (en) 1998-08-19 2002-12-31 Powerzyme, Inc. Enzymatic fuel cell
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
ES2357887T3 (es) 2001-06-12 2011-05-03 Pelikan Technologies Inc. Aparato para mejorar la tasa de éxito de obtención de sangre a partir de una punción capilar.
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
EP1404232B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Gerät und verfahren zur entnahme von blutproben
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
WO2002100843A1 (fr) * 2001-06-13 2002-12-19 Jianqing Lu Composes phenoxazines, preparations les contenant et leurs utilisations medicinales
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7648468B2 (en) * 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7265881B2 (en) * 2002-12-20 2007-09-04 Hewlett-Packard Development Company, L.P. Method and apparatus for measuring assembly and alignment errors in sensor assemblies
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
ES2347248T3 (es) 2003-05-30 2010-10-27 Pelikan Technologies Inc. Procedimiento y aparato para la inyeccion de fluido.
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
US9775553B2 (en) * 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
JP5395665B2 (ja) 2006-09-22 2014-01-22 バイエル・ヘルスケア・エルエルシー 改善された安定性およびヘマトクリット性能（ｐｅｒｆｏｒｍａｎｃｅ）を有するバイオセンサー系
EP2679150B1 (de) * 2006-10-24 2020-07-22 Ascensia Diabetes Care Holdings AG Nachwirkungsstrommessung
BRPI0817189A2 (pt) * 2007-09-24 2015-03-17 Bayer Healthcare Llc Sensores de teste de multi-região e de potencial, métodos, e sistemas
BRPI0820585A2 (pt) 2007-12-10 2015-06-16 Bayer Healthcare Llc Processo de tomada 3-phenylimino-3h-fenotiazina ou 3- phenylimino-3h-phenoxazine mediador
BRPI0820721A2 (pt) 2007-12-10 2015-06-16 Bayer Healthcare Llc Reagentes e métodos para detectar analitos
ES2664574T3 (es) * 2007-12-10 2018-04-20 Ascensia Diabetes Care Holdings Ag Composiciones reactivas de partículas porosas, dispositivos y métodos para biosensores
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
EP3435077A1 (de) 2008-07-10 2019-01-30 Ascensia Diabetes Care Holdings AG Systeme und verfahren mit amperometrischem und voltametrische arbeitszyklen
RU2546862C2 (ru) 2008-12-08 2015-04-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Биосенсорная система и тестовые сенсоры для определения концентрации анализируемого вещества (варианты)
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8283347B2 (en) * 2009-06-01 2012-10-09 Bayer Healthcare Llc Redox molecules and methods of making the same
CN102597759B (zh) 2009-11-10 2016-01-13 拜尔健康护理有限责任公司 用于生物传感器的未足量识别系统
US20120252046A1 (en) 2009-12-17 2012-10-04 Bayer Healthcare Llc Transdermal systems, devices, and methods for biological analysis
US9354226B2 (en) 2009-12-17 2016-05-31 Ascensia Diabetes Care Holdings Ag Transdermal systems, devices, and methods to optically analyze an analyte
US9233788B2 (en) 2010-01-22 2016-01-12 Bayer Healthcare Llc Biosensor desiccant system having enhanced measurement performance
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8742063B2 (en) 2010-05-28 2014-06-03 Bayer Healthcare Llc Polymer bonded redox molecules and methods of making the same
TWI565943B (zh) 2011-07-22 2017-01-11 拜耳保健公司 具有增進測量性能之生物感測器乾燥劑系統
WO2014114810A1 (en) 2013-01-28 2014-07-31 Roche Diagnostics Gmbh Novel glucose oxidases derived from aspergillus niger
JP6659669B2 (ja) * 2014-08-22 2020-03-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ レドックス指示薬
CN110642845B (zh) * 2019-09-30 2021-01-05 中国人民解放军军事科学院军事医学研究院 一种喹啉衍生物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982003729A1 (en) * 1981-04-08 1982-10-28 Lo Gorton Electrode for the electrochemical regeneration of co-enzyme,a method of making said electrode,and the use thereof
GB8424709D0 (en) * 1984-10-01 1984-11-07 Minnesota Mining & Mfg Azine redox dyes and leuco azine dyes
IL102930A (en) * 1992-08-25 1997-03-18 Yissum Res Dev Co Electrobiochemical analytical method and electrodes
US5393615A (en) * 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
US5498542A (en) * 1994-09-29 1996-03-12 Bayer Corporation Electrode mediators for regeneration of NADH and NADPH
JPH08304329A (ja) * 1995-05-09 1996-11-22 Kdk Corp 多孔性膜を使用したバイオセンサー、および該多孔性膜の 製造方法

Also Published As

Publication number Publication date
CA2152410A1 (en) 1996-03-30
DE69524175T2 (de) 2002-05-02
AU689630B2 (en) 1998-04-02
EP0704535A3 (de) 1997-07-16
CA2152410C (en) 2004-02-17
EP0704535B1 (de) 2001-11-28
JPH08100284A (ja) 1996-04-16
JP3814314B2 (ja) 2006-08-30
US5498542A (en) 1996-03-12
AU3293695A (en) 1996-04-18
EP0704535A2 (de) 1996-04-03

Similar Documents

Publication Publication Date Title
DE69524175T2 (de) Vermittler, geeignet für die elektrochemische Regenerierung von NADH, NADPH oder deren Analogen
DE69622936D1 (de) Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen
ATE206466T1 (de) Vermittler, geeignet für die elektrochemische regenerierung von nadh, nadph oder deren analoga
BR8502432A (pt) Mancal para motor,de duas camaras,com amortecimento hidraulico
DE3582953D1 (de) Faserhaltige, teilchenfoermige elastomerzusammensetzung.
DE3787883D1 (de) Geschichtetes Verbundbauteil für glatte Oberflächen.
NO854639L (no) Formgitte hydrogelgjenstander.
DE3576082D1 (de) Verbundelektrode, verfahren zu ihrer herstellung und ihre anwendung.
AT385900B (de) Einsatzfahrzeug, insbesondere feuerwehrfahrzeug
DE3750899T2 (de) Polymer für Toner, dessen Herstellungsverfahren und Tonerzusammensetzung.
ES545110A0 (es) Proceso para la formacion de laminados fibrosos impregnados.
FI842115A0 (fi) Pressparti med separata pressnyp i en pappersmaskin.
DE69206555T2 (de) Anode für elektrochemische Fluorzelle.
DE3484531D1 (de) Tetrahydrobenzotriazole, deren herstellung und verwendung.
DE69105398T2 (de) Separatoren für elektrochemische Zellen.
DK164117C (da) Fortyknet, vandig rensemiddelkomposition
DK545484D0 (da) 2,5 -diketo-d-gluconsyrereduktase
DE68908098T2 (de) Anodenzusammenstellung für die selektive Galvanisierung von Innenoberflächen von Kontaktelementen.
PT84706B (pt) Processo para a funcionalizacao de iodo-polifluoroalcanos mediante reducao electroquimica
ES285188Y (es) Conjunto de elementos para la realizacion de cubiertas lige-ras, en especial marquesinas
DE3587988D1 (de) Behandlungsverfahren für depressionen bei wirbeltieren.
ES545447A0 (es) Procedimiento para la utilizacion de agentes decapantes,par-ticularmente para el decapado de piezas de trabajo
DE69213367T2 (de) Dichtungsanordnung, insbesondere für Wälzlager
DE3577869D1 (de) Neue metallkomplexe, verfahren zu deren herstellung und verwendung.
ES278419Y (es) Estructura metalica para la fijacion de paneles, en la construccion de unidades prefabricadas.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition