DE69521328T2 - Kaffein-formulierung mit verzögerter freisetzung - Google Patents

Kaffein-formulierung mit verzögerter freisetzung

Info

Publication number
DE69521328T2
DE69521328T2 DE69521328T DE69521328T DE69521328T2 DE 69521328 T2 DE69521328 T2 DE 69521328T2 DE 69521328 T DE69521328 T DE 69521328T DE 69521328 T DE69521328 T DE 69521328T DE 69521328 T2 DE69521328 T2 DE 69521328T2
Authority
DE
Germany
Prior art keywords
delayed release
caffeine formulation
caffeine
formulation
delayed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69521328T
Other languages
English (en)
Other versions
DE69521328D1 (de
Inventor
Francoise Chauffard
Marc Y A Enslen
Pierre Tachon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe des Produits Nestle SA, Nestle SA filed Critical Societe des Produits Nestle SA
Application granted granted Critical
Publication of DE69521328D1 publication Critical patent/DE69521328D1/de
Publication of DE69521328T2 publication Critical patent/DE69521328T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
DE69521328T 1994-12-16 1995-11-27 Kaffein-formulierung mit verzögerter freisetzung Expired - Lifetime DE69521328T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/357,689 US5744164A (en) 1994-12-16 1994-12-16 Sustained release microparticulate caffeine formulation
PCT/IB1995/001056 WO1996018389A1 (en) 1994-12-16 1995-11-27 Sustained release caffeine formulation

Publications (2)

Publication Number Publication Date
DE69521328D1 DE69521328D1 (de) 2001-07-19
DE69521328T2 true DE69521328T2 (de) 2002-01-17

Family

ID=23406640

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521328T Expired - Lifetime DE69521328T2 (de) 1994-12-16 1995-11-27 Kaffein-formulierung mit verzögerter freisetzung

Country Status (21)

Country Link
US (2) US5744164A (de)
EP (2) EP0716853A1 (de)
JP (1) JPH10510529A (de)
AR (1) AR002947A1 (de)
AT (1) ATE201986T1 (de)
AU (1) AU694810B2 (de)
CA (1) CA2208149C (de)
CO (1) CO4600671A1 (de)
DE (1) DE69521328T2 (de)
DK (1) DK0789562T3 (de)
ES (1) ES2158956T3 (de)
GR (1) GR3036501T3 (de)
HK (1) HK1000878A1 (de)
IL (1) IL116066A (de)
NZ (1) NZ295245A (de)
PE (1) PE55396A1 (de)
PT (1) PT789562E (de)
RU (1) RU2144353C1 (de)
TR (1) TR199501560A2 (de)
WO (1) WO1996018389A1 (de)
ZA (1) ZA9510687B (de)

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US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
US6586023B1 (en) 1998-12-15 2003-07-01 Wm. Wrigley Jr. Company Process for controlling release of active agents from a chewing gum coating and product thereof
US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US7935362B2 (en) * 1999-04-06 2011-05-03 Wm. Wrigley Jr. Company Over-coated product including consumable center and medicament
US6322806B1 (en) 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
US20020159956A1 (en) * 1999-04-06 2002-10-31 Ream Ronald L. Over-coated chewing gum formulations
US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US9253991B2 (en) 1999-09-20 2016-02-09 Jack Barreca Chewing gum with B vitamins
US6491540B1 (en) * 1999-09-20 2002-12-10 Jack Barreca Center-filled supplement gum
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
US8178150B2 (en) 2000-02-22 2012-05-15 Suzanne Jaffe Stillman Water containing soluble fiber
US7115297B2 (en) 2000-02-22 2006-10-03 Suzanne Jaffe Stillman Nutritionally fortified liquid composition with added value delivery systems/elements/additives
US7892586B2 (en) 2001-02-22 2011-02-22 Suzanne Jaffe Stillman Water containing soluble fiber
US7115288B2 (en) * 2000-06-09 2006-10-03 Wm. Wrigley Jr. Company Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
US6444241B1 (en) 2000-08-30 2002-09-03 Wm. Wrigley Jr. Company Caffeine coated chewing gum product and process of making
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
US7897141B2 (en) * 2002-04-01 2011-03-01 Drexel University Echogenic polymer microcapsules and nanocapsules and methods for production and use thereof
US20030220351A1 (en) * 2002-05-24 2003-11-27 Gilbert Gonzales Enteric coated caffeine tablet
AU2003292110A1 (en) * 2002-11-25 2004-06-18 Phares Pharmaceutical Research N.V. Confectionery composition
US20050181044A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements, green coffee extract
US20050220875A1 (en) * 2004-03-31 2005-10-06 Agency For Science, Technology And Research Sustained-release tablet formulation
FR2883179B1 (fr) 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US8486452B2 (en) 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US7985728B1 (en) 2007-09-20 2011-07-26 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
US9173890B2 (en) * 2007-09-20 2015-11-03 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
US8101565B2 (en) * 2007-09-20 2012-01-24 Abbott Cardiovascular Systems Inc. Sustained release of Apo A-I mimetic peptides and methods of treatment
US7985727B1 (en) 2007-09-20 2011-07-26 Abbott Cardiovascular Systems Inc. Apo A-I mimetic peptides and methods of treatment
US8044021B2 (en) * 2007-09-20 2011-10-25 Abbott Cardiovascular Systems Inc. Sustained release of apo A-I mimetic peptides and methods of treatment
RU2571067C2 (ru) * 2009-01-22 2015-12-20 Эбботт Хелткеа Прайвит Лимитед Хронотерапевтическая фармацевтическая композиция
US8545892B2 (en) 2009-06-26 2013-10-01 Nano Pharmaceutical Laboratories, Llc Sustained release beads and suspensions including the same for sustained delivery of active ingredients
US8992898B2 (en) 2010-04-17 2015-03-31 Shannon Elizabeth Klingman Antiperspirants and deodorants
US20160128943A1 (en) * 2013-06-04 2016-05-12 KVK-Tech, Inc. Controlled release caffeine dosage forms
CA2978593A1 (en) 2015-01-12 2016-07-21 Nano Pharmaceutical Laboratories Llc Layered sustained-release microbeads and methods of making the same
KR101644154B1 (ko) * 2015-09-08 2016-07-29 주식회사 스킨앤테크 수용성 카페인 및 그 제조방법
US10582716B1 (en) 2019-06-14 2020-03-10 Lennham Pharmaceuticals, Inc. Deuterated caffeine and uses thereof
US20220288083A1 (en) * 2021-03-09 2022-09-15 Lennham Pharmaceuticals, Inc. D9-caffeine compositions and uses thereof
CN117750947A (zh) * 2021-07-30 2024-03-22 宝龄富锦生技股份有限公司 控制释放口服制剂及其制备方法

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US3265629A (en) * 1958-12-22 1966-08-09 Ncr Co Coating by phase separation
DE1249219B (de) * 1958-12-22 1967-09-07 The National Cash Register Company, Dayton, Ohio (V. St. A.) Herstellen von Mikrokapseln, die eine Emulsion aus Öl in hydrophiler Flüssigkeit enthalten
DE2010416B2 (de) * 1970-03-05 1979-03-29 Hoechst Ag, 6000 Frankfurt Oral anwendbare Arzneiform mit Retardwirkung
US4001480A (en) * 1974-08-16 1977-01-04 Swift & Company Encapsulation process utilizing microorganisms and products produced thereby
IE55745B1 (en) * 1983-04-06 1991-01-02 Elan Corp Plc Sustained absorption pharmaceutical composition
NZ207813A (en) * 1983-06-24 1986-12-05 Dridrinks Nv Effervescent mixture:component(s)coated with water-soluble polysaccharide composition
DE3474099D1 (en) * 1983-06-24 1988-10-27 Dridrinks Nv Treatment of acids as compounds of water-soluble, powdery compositions intended for preparing beverages with lasting gaseous delivery.
NZ210785A (en) * 1984-01-13 1987-11-27 Battelle Development Corp Liquid dispersions of layered controlled release dosage forms
DE3403329A1 (de) * 1984-02-01 1985-08-01 Horst Dr. 4019 Monheim Zerbe Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
DE3586600T2 (de) * 1984-02-10 1993-02-18 Benzon Pharma As Dosierungsform eine vielzahl mit einer diffusionshuelle ueberzogener einheiten enthaltend.
NL8500724A (nl) * 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
DE3537770A1 (de) * 1985-10-24 1987-04-30 Basf Ag Salze mehrwertiger kationen von polymerisaten von konjugierten dienen
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US5026709A (en) * 1986-04-07 1991-06-25 Rorer Pharmaceutical Corporation Method for the preparation of a theophylline sustained release pharmaceutical composition and the composition prepared thereby
AU7280387A (en) * 1986-04-07 1987-11-09 Rorer International (Overseas) Inc. Method for the preparation of a sustained release pharmaceutical composition and the compostion prepared thereby
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US5200193A (en) * 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
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US5330766A (en) * 1989-01-06 1994-07-19 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
CA2007181C (en) * 1989-01-06 1998-11-24 Angelo Mario Morella Sustained release pharmaceutical composition
JPH06316517A (ja) * 1993-02-22 1994-11-15 Grelan Pharmaceut Co Ltd 放出制御製剤

Also Published As

Publication number Publication date
AR002947A1 (es) 1998-05-27
HK1000878A1 (en) 2001-10-26
ATE201986T1 (de) 2001-06-15
WO1996018389A1 (en) 1996-06-20
US5744164A (en) 1998-04-28
ZA9510687B (en) 1996-07-03
IL116066A0 (en) 1996-01-31
DK0789562T3 (da) 2001-09-03
US5700484A (en) 1997-12-23
NZ295245A (en) 1999-01-28
GR3036501T3 (en) 2001-11-30
IL116066A (en) 2000-10-31
CO4600671A1 (es) 1998-05-08
PT789562E (pt) 2001-10-30
RU2144353C1 (ru) 2000-01-20
JPH10510529A (ja) 1998-10-13
CA2208149A1 (en) 1996-06-20
EP0789562B1 (de) 2001-06-13
AU694810B2 (en) 1998-07-30
ES2158956T3 (es) 2001-09-16
PE55396A1 (es) 1996-12-24
AU3854295A (en) 1996-07-03
EP0716853A1 (de) 1996-06-19
DE69521328D1 (de) 2001-07-19
CA2208149C (en) 2007-03-27
TR199501560A2 (tr) 1996-07-21
EP0789562A1 (de) 1997-08-20

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Legal Events

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8364 No opposition during term of opposition